Mario van der Stelt
Hoogleraar Moleculaire fysiologie
- Naam
- Prof.dr. M. van der Stelt
- Telefoon
- +31 71 527 4768
- m.van.der.stelt@chem.leidenuniv.nl
- ORCID iD
- 0000-0002-1029-5717
Meer informatie op de Engelstalige profielpagina
Meer informatie over Mario van der Stelt
Promovendi
Nieuws
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Van druppeltjes in de vriezer tot het begin van een krachtig nieuw antibioticum -
Speuren in de hersenen naar oorzaken psychiatrische ziekten -
Zwaartekracht-subsidies voor vijf projecten met Leidse onderzoekers -
Nieuw potentieel geneesmiddel onderdrukt door chemotherapie veroorzaakte neuropathische pijn -
Oncode Accelerator van start: patiënt centraal bij innovatieve ontwikkeling kankermedicijnen -
De moleculaire geheimen van medicinale cannabis -
Hoe Oncode-PACT met 325 miljoen Groeifonds-geld nieuwe kankergeneesmiddelen dichterbij brengt -
Het Nationaal Groeifonds investeert vele miljoenen in snellere en duurzamere (kanker)medicijnontwikkeling -
Samenwerking van instituten tegen TBC in het Leidsch Dagblad -
Leidse onderzoekers slaan handen ineen tegen tuberculose -
Medical Delta AI for Computational Life Sciences -
De Erasmus+ beurs opent deuren -
Nieuwe techniek geeft chemici ongekende controle in medicijnonderzoek -
Verschillende media berichten over de rol van lichaamseigen marihuana -
Lichaamseigen marihuana zorgt dat je angstherinneringen vergeet -
Samen tegen kanker: Mario van der Stelt sluit zich aan bij Oncode Institute -
Lichaamseigen marihuana als inspiratie voor geneesmiddelenonderzoek -
Profileringsprogramma over lichaamseigen marihuana brengt instituten bij elkaar -
VICI voor Mario van der Stelt
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Drie VICI’s voor Leidse wetenschappers -
Mario van der Stelt benoemd tot hoogleraar Moleculaire Fysiologie -
Leidse wetenschappers in de prijzen tijdens Dutch Medicines Days -
Op zoek naar betere medicijnen en behandelingen voor kanker -
Diverse media over medicijnonderzoek Mario van der Stelt -
Experimenteel geneesmiddel BIA 10-2474 schakelt meerdere eiwitten uit in menselijke zenuwcellen
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Marc Baggelaar promoveert cum laude op lichaamseigen marihuana -
High-vrije wiet in trek bij NOS op 3 -
Pijnstilling zonder high te zijn
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Nieuwe stoffen remmen ontsteking in het brein -
Wetenschappers vinden achterdeur voor medicijnen -
Medicijnontwikkeling, hoe kan het efficiënter? -
Nieuwe meetmethode versnelt geneesmiddelenonderzoek -
TA-premies voor onderzoek naar nieuwe geneesmiddelen voor kanker en allergieën -
Europese ‘stoffenbibliotheek’ voor ontwikkeling van nieuwe medicijnen
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Ruim een miljoen voor Leids excellent onderzoek chemie -
Nieuwe sensor ziet hoe eiwitten in hersenen betrokken zijn bij obesitas -
Vier grote subsidies voor excellente Leidse onderzoekers in de chemie -
Europese ‘stoffenbibliotheek’ voor ontwikkeling van nieuwe medicijnen
Op 19 oktober 2018 sprak Mario van der Stelt zijn oratie uit, getiteld 'Lichaamseigen marihuana: inspiratie voor geneesmiddelenonderzoek'.
Hij is lid van het interdisciplinaire onderzoeksprogramma Society, Artificial Intelligence and Life Sciences (SAILS). Meer informatie op de Engelstalige profielpagina.
Hoogleraar Moleculaire fysiologie
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Molecular Physiology
- Butini S., Grether U., Jung K.-M., Ligresti A., Allara M., Postmus A.G.J., Maramai S., Brogi S., Papa A., Carullo G., Sykes D., Veprintsev D., Federico S., Grillo A., Di Guglielmo B., Ramunno A., Stevens A.F., Heer D., Lamponi S., Gemma S., Benz J., Di Marzo V., Stelt M. van der, Piomelli D. & Campiani G. (2024), Development of potent and selective monoacylglycerol lipase inhibitors: SARs, structural analysis, and biological characterization, Journal of Medicinal Chemistry 67(3): 1758-1782.
- Paus L.V. de, Yu A., Janssen A.P.A., Berg R.J.B.H.N. van den, Heitman L.H. & Stelt M. van der (2024), Discovery of a photoaffinity probe that captures the active conformation of the cannabinoid CB2 receptor, ChemBioChem 25(7): e202300785.
- Bakker A.T., Kotsogianni I., Avalos Garcia M., Punt J.M., Liu B., Piermarini D., Gagestein B., Slingerland C.J., Zhang L., Willemse J.J., Ghimire L.B., Berg Richard J.H.B.N. van den, Janssen A.P.A., Ottenhoff T.H.M., Boeckel C.A.A. van, Wezel G.P. van, Ghilarov D., Martin N.I. & Stelt M. van der (2024), Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria, Nature Chemistry 16: 1462-1472.
- Berger N., Wel T. van der, Hirschmugl B., Baernthaler T., Gindlhuber J., Fawzy N., Eichmann T., Birner-Gruenberger R., Zimmermann R., Stelt M. van der & Wadsack C. (2023), Inhibition of diacylglycerol lipase beta modulates lipid and endocannabinoid levels in the ex vivo human placenta, Frontiers in Endocrinology 14: 1092024.
- Zhu N., Janssen A.P.A. & Stelt M. van der (2023), Understanding and targeting the endocannabinoid system with activity-based protein profiling, Israel Journal of Chemistry 63(3-4): e202200115.
- Petrie G.N., Balsevich G., Fuzesi T., Aukema R.J., Driever W.P.F., Stelt M. van der, Bains J.S. & Hill M.N. (2023), Disruption of tonic endocannabinoid signalling triggers cellular, behavioural and neuroendocrine responses consistent with a stress response, British Journal of Pharmacology 180(24): 3146-3159.
- Bouma, J., Broekhuis J.D., Horst C. van der, Kumar P., Ligresti A., Stelt M. van der & Heitman L.H. (2023), Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor, Biochemical Pharmacology 218: 115924.
- Krift F. van der, Zijlmans D.W., Shukla R., Javed A., Koukos P.I., Schwarz L.L., Timmermans-Sprang E.P., Maas P.E., Gahtory D., Nieuwboer M. van den, Mol J.A., Strous G.J., Bonvin A.M., Stelt M. van der, Veldhuizen E.J., Weingarth M., Vermeulen M., Klumperman J. & Maurice M.M. (2023), A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance, Life Science Alliance 6(11): e202302058.
- Fellner M., Walsh A., Dela Ahator S., Aftab N., Sutherland B., Tan E.W., Bakker A.T., Martin N.I., Stelt M. van der & Lentz C.S. (2023), Biochemical and cellular characterization of the function of fluorophosphonate-binding hydrolase H (FphH) in staphylococcus aureus support a role in bacterial stress response, ACS infectious diseases 9(11): 2119-2132.
- Maccarrone M., Marzo V. Di, Gertsch J., Grether U., Howlett A.C., Hua T., Makriyannis A., Piomelli D., Ueda N. & Stelt M. van der (2023), Goods and bads of the endocannabinoid system as a therapeutic target: lessons learned after 30 years, Pharmacological Reviews 75(5): 885-958.
- Jiang M., Huizenga M.C.W., Wirth J.L., Paloczi J., Amedi A., Berg R.J.B.H.N. van den, Benz J., Collin L., Deng H., Di X., Driver W.F., Florea B.I., Grether U., Janssen A.P.A., Hankemeier T., Heitman L.H., Lam T.W., Mohr F., Pavlovic A., Ruf I., Hurk H. van den, Stevens A.F., Vliet D. van der, Wel T. van der, Wittwer M.B., Boeckel C.A.A. van, Pacher P., Hohmann A.G. & Stelt M. van der (2023), A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence, Nature Communications 14(1): 8039.
- Bakker A.T., Kotsogianni A.I., Mirenda L., Straub V.M., Avalos Garcia M., Berg R.J.B.H.N. van den, Florea B.I., Wezel G.P. van, Janssen A.P.A., Martin N.I. & Stelt M. van der (2023), Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA, Journal of the American Chemical Society 145(2): 1136-1143.
- Colangeli R., Morena M., Werner A., Thompson R.J., Stelt M. van der, Pittman Q.J., Hill M.N. & Teskey G.C. (2023), 2-AG-mediated control of GABAergic signaling is impaired in a model of epilepsy, Journal of Neuroscience 43(4): 571-583.
- Mock E.D., Gagestein B. & Stelt M. van der (2023), Anandamide and other N-acylethanolamines: a class of signaling lipids with therapeutic opportunities, Progress in Lipid Research 89: 101194.
- Zadelhoff G. van & Stelt M. van der (2023), Oxygenation of anandamide by lipoxygenases. In: Maccarrone M. (red.), Endocannabinoid signaling. Methods in Molecular Biology nr. 2576. New York: Humana. 307-316.
- Mock E.D., Driever W.P.F. & Stelt M. van der (2023), Fluorescence-based NAPE-PLD activity assay. In: Maccarrone M. (red.), Endocannabinoid signaling. Methods in Molecular Biology nr. 2576. New York: Humana. 233-240.
- Auberson Y.P., Arimondo P.B., Duca M., Essig S., Grether U., Rufer A.C, Sbardella G., Schopfer U., Torrens A., Stelt M. van der, Vauzeilles B., Vázquez O. & Zhang A.X. (2023), EFMC : trends that link medicinal chemistry and chemical biology to translational drug discovery, ChemBioChem 24(7): e202200690.
- Li X., Chang H., Bouma J., Paus L.V. de, Mukhopadhyay P., Paloczi J., Mustafa M., Horst C. van der, Kumar S.S., Wu L., Yu Y., Berg R.J.B.H.N. van den, Janssen A.P.A., Lichtman A., Liu Z.J., Pacher P., Stelt M. van der, Heitman L.H. & Hua T. (2023), Structural basis of selective cannabinoid CB2 receptor activation, Nature Communications 14(1): 1447.
- Al Ayed U.K., Ballantine R.D., Hoekstra M., Bann S.J., Wesseling C.M.J., Bakker A.T., Zhong Z., Li Y.X., Brüchle N.C., Stelt M. van der, Cochrane S.A. & Martin N.I. (2022), Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy, Chemical Science 13(12): 3563-3570.
- Gagestein B., Stevens A.F., Fazio D., Florea B.I., Wel T. van der, Bakker A.T., Fezza F., Dulk J. den, Overkleeft H.S., Maccarrone M. & Stelt M. van der (2022), Chemical proteomics reveals off-targets of the anandamide reuptake inhibitor WOBE437, ACS Chemical Biology 17(5): 1174-1183.
- Gazzi T., Brennecke B., Atz K., Korn C., Sykes D., Forn-Cuni G., Pfaff P., Sarott R.C., Westphal M.V., Mostinski Y., Mach L., Wasinska-Kalwa M., Weise M., Hoare B.L., Miljuš T., Mexi M., Roth N., Koers E.J., Guba W., Alker A., Rufer A.C., Kusznir E.A., Huber S., Raposo C., Zirwes E.A., Osterwald A., Pavlovic A., Moes S., Beck J., Nettekoven M., Benito-Cuesta I., Grande T., Drawnel F., Widmer G., Holzer D., Wel T. van der, Mandhair H., Honer M., Fingerle J., Scheffel J., Broichhagen J., Gawrisch K., Romero J., Hillard C.J., Varga Z.V., Stelt M. van der, Pacher P., Gertsch J., Ullmer C., McCormick P.J., Oddi S., Spaink H.P., Maccarrone M., Veprintsev D.B., Carreira E.M., Grether U. & Nazaré M. (2022), Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe, Chemical Science 13(19): 5539-5545.
- Bertheussen K., Plassche M.A.T. van de, Bakkum T., Gagestein B., Ttofi I., Sarris A.J.C., Overkleeft H.S., Stelt M. van der & Kasteren S.I. van (2022), Live-cell imaging of sterculic acid - a naturally occurring 1,2-cyclopropene fatty acid - by bioorthogonal reaction with turn-on tetrazine-fluorophore conjugates, Angewandte Chemie (International Edition) 61(38): e202207640.
- Ortiz-Alvarez L., Xu H., Di X., Kohler I., Osuna-Prieto F.J., Acosta F.M., Vilchez-Vargas R., Link A., Plaza-Díaz J., Stelt M. van der, Hankemeier T., Clemente-Postigo M., Tinahones F.J., Gil A., Rensen P.C.N., Ruiz J.R. & Martinez-Tellez B. (2022), Plasma levels of endocannabinoids and their analogues are related to specific fecal bacterial genera in young adults: role in gut barrier integrity, Nutrients 14(10): 2143.
- Bouma J., Soethoudt M., Gils N. van, Xia L., Stelt M van der & Heitman L.H. (2022), Cellular assay to study β-arrestin recruitment by the cannabinoid receptors 1 and 2. In: Maccarrone M. (red.), Endocannabinoid Signaling. Methods in Molecular Biology nr. 2576. New York, U.S.A.: Humana. 189-199.
- Punt J.M., Vliet D. van der & Stelt M. van der (2022), Chemical Probes to Control and Visualize Lipid Metabolism in the Brain, Accounts of Chemical Research 55(22): 3205-3217.
- Gagestein B., von Hegedus J.H., Kwekkeboom J.C., Heijink M., Blomberg N., Wel T. van der, Florea B.I., Elst H. van der, Wals K., Overkleeft H.S., Giera M., Toes R.E.M., Ioan-Facsinay A. & Stelt M. van der (2022), Comparative photoaffinity profiling of omega-3 signaling lipid probes reveals prostaglandin reductase 1 as a metabolic hub in human macrophages, Journal of the American Chemical Society 144(41): 18938–18947.
- He Y.F., Grether U., Taddio M.F., Meier C., Keller C., Edelmann M.R., Honer M., Huber S., Wittwer M.B., Heer D., Richter H., Collin L., Hug M.N., Hilbert M., Postmus A.G.J., Stevens A.F., Stelt M. van der, Kramer S.D., Schibli R., Mu L.J. & Gobbi L.C. (2022), Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain, European Journal of Medicinal Chemistry 243: 114750.
- Bakker A.T., Kotsogianni A.I., Mirenda L., Straub V.M., Avalos Garcia M., Berg R.J.B.H.N. van den, Florea B.I., Wezel G.P. van, Janssen A.P.A., Martin N.I. & Stelt M. van der (2022), Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA, Journal of the American Chemical Society 145(2): 1136-1143.
- Mock E.D., Kotsogianni I., Driever W.P.F., Fonseca C.S., Vooijs J.M., Dulk H. den, Boeckel C.A.A. van & Stelt M. van der (2021), Structure–activity relationship studies of pyrimidine-4-carboxamides as inhibitors of N-acylphosphatidylethanolamine phospholipase D, Journal of Medicinal Chemistry 64(1): 481-515.
- Egmond N. van, Straub V.M. & Stelt M. van der (2021), Targeting endocannabinoid signaling: FAAH and MAG lipase inhibitors, Annual Review of Pharmacology and Toxicology 61: 441-463.
- Eenige R. van, Ying Z., Tambyrajah L, Pronk A.C.M., Blomberg N., Giera M., Wang Y., Coskun T., Stelt M. van der, Rensen P.C.N. & Kooijman S. (2021), Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice, Journal of Lipid Research 62: 100070.
- Chatterjee S.D. Zhou J. Dasgupta R. Cramer-Blok A.J. Timmer M. Stelt M. van der Ubbink M. (2021), Protein dynamics influence the enzymatic activity of phospholipase a/acyltransferases 3 and 4, Biochemistry 60(15): 1178-1190.
- Bos A.V., Erkelens M.N., Koenders S.T.A., Stelt M. van der, Egmond M. van & Mebius R.E. (2021), Clickable Vitamins as a New Tool to Track Vitamin A and Retinoic Acid in Immune Cells, Frontiers in Immunology 12: 671283.
- Duca M., Gillingham D., Olsen C.A., Sbardella G., Skaanderup P.R., Stelt M. van der, Vauzeilles B., Vázquez O. & Auberson Y.P. (2021), The chemical biology-medicinal chemistry continuum: EFMC's vision, ChemBioChem 22(19): 2823-2825.
- Alexander S.P., Fabbro D., Kelly E., Mathie A., Peters J.A., Veale E.L., Armstrong J.F., Faccenda E., Harding S.D., Pawson A.J., Southan C., Davies J.A., Boison D., Burns K.E., Dessauer C., Gertsch J., Helsby N.A., Izzo A.A., Koesling D., Ostrom R., Pyne N.J., Pyne S., Russwurm M., Seifert R., Stasch J.P., Stelt M. van der, Vliet A. van der, Watts V. & Wong S.S. (2021), The concise guide to pharmacology 2021/2: enzymes, British Journal of Pharmacology 178(S1): S313-S411.
- Jones P.S., Boucharens S., McElroy S.P., Morrison A., Honarnejad S., Boeckel S. van, Hurk H. van den, Basting D., Hüser J., Jaroch S., Ottow E., Benningshof J., Folmer R.H.A., Leemhuis F., Kramer-Verhulst P.M., Nies V.J.M., Orrling K.M., Rijnders T., Pfander C., Engkvist O., Pairaudeau G., Simpson P.B., Ortholand J.Y., Roche D., Dömling A., Kühnert S.M., Roevens P.W.M., Vlijmen H. van, Wanrooij E.J.A. van, Verbruggen C., Nussbaumer P., Ovaa H., Stelt M. van der, Simonsen K.B., Tagmose L., Waldmann H., Duffy J., Finsinger D., Jurzak M., Burgess-Brown N.A., Lee W.H., Rutjes F.P.J.T., Haag H., Kallus C., Mors H., Dorval T., Lesur B., Ramon Olayo F., Hamza D., Jones G., Pearce C., Piechot A., Tzalis D., Clausen M.H., Davis J., Derouane D., Vermeiren C., Kaiser M., Stockman R.A., Barrault D.V., Swedlow J.R., Nelson A.S., Orru R.V.A., Ruijter E., Helden S.P. van, Li V.M., Vries T. & Vlieger J.S.B. de (2021), IMI European Lead Factory : democratizing access to high-throughput screening, Nature Reviews Drug Discovery 20(2): 85-90.
- Prokop S., Ábrányi-Balogh P., Barti B., Vámosi M., Zöldi M., Barna L., Urbán G.M., Tóth A.D., Dudok B., Egyed A., Deng H., Leggio G.M., Hunyady L., Stelt M. van der, Keserű G.M. & Katona I. (2021), PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells, Nature Communications 12: 6505.
- Gianessi C.A., Groman S.M., Thompson S.L., Jiang M., Stelt M. van der & Taylor J.R. (2020), Endocannabinoid contributions to alcohol habits and motivation: Relevance to treatment, Addiction Biology 25(3): e12768.
- Yasmin F., Colangeli R., Morena M., Filipski S., Stelt M. van der, Pittman Q.J., Hillard C.J., Teskey G.C., McEwen B.S., Hill M.N. & Chattarji S. (2020), Stress-induced modulation of endocannabinoid signaling leads to delayed strengthening of synaptic connectivity in the amygdala, Proceedings of the National Academy of Sciences 117(1): 650-655.
- Zhang H., Lapointe B.T., Anthony N., Azevedo R., Cals J., Correll C.C., Daniels M., Deshmukh S., Eenenaam H. van, Ferguson H., Hegde L.G., Karstens W.J., Maclean J., Miller J.R., Moy L.Y., Simov V., Nagpal S., Oubrie A., Palte R.L., Parthasarathy G., Sciammetta N., Stelt M. van der, Woodhouse J.D., Trotter B.W. & Barr K. (2020), Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases, ACS Medicinal Chemistry Letters 11(2): 114-119.
- Armstrong Z., Kuo C.L., Lahav D., Liu B., Johnson R., Beenakker T.J.M., Boer C. de, Wong C.S., Rijssel E.R. van, Debets M.F., Florea B.I., Hissink C., Boot R.G., Geurink P.P., Ovaa H., Stelt M. van der, Marel G.A. van der, Codée J.D.C., Aerts J.M.F.G., Wu L., Overkleeft H.S. & Davies G.J. (2020), Manno-epi-cyclophellitols enable activity-based protein profiling of human α-mannosidases and discovery of new golgi mannosidase II inhibitors, Journal of the American Chemical Society 142(30): 13021-13029.
- Wel T. van der Hilhorst R Dulk H. den Hooven T. van den Prins N.M. Wijnakker J.A.P.M. Florea B.I. Lenselink E.B. Westen G.J.P. van Ruijtenbeek R. Overkleeft H.S. Kaptein A. Barf T. Stelt M. van der (2020), Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis, Nature Communications 11(1): 3216.
- Mock E.D., Mustafa M., Gunduz-Cinar O., Cinar R., Petrie G.N., Kantae V., Di X., Ogasawara D., Varga Z.V., Paloczi J., Miliano C., Donvito G., Esbroeck A.C.M. van, Gracht A.M.F. van der, Kotsogianni I., Park J.K., Martella A., Wel T. van der, Soethoudt M., Jiang M., Wendel T.J., Janssen A.P.A., Bakker A.T., Donovan C.M., Castillo L.I., Florea B.I., Wat J., Hurk H. van den, Wittwer M., Grether U., Holmes A., Boeckel C.A.A. van, Hankemeier T., Cravatt B.F., Buczynski M.W., Hill M.N., Pacher P., Lichtman A.H. & Stelt M. van der (2020), Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nature Chemical Biology 16(6): 667-675.
- Voorneveld J., Florea B.I., Bakkum T., Mendowicz R.J., Veer M.S. van der, Gagestein B., Kasteren S.I. van, Stelt M. van der, Overkleeft H.S. & Filippov D.V. (2020), Olaparib-Based Photoaffinity Probes for PARP-1 Detection in Living Cells, ChemBioChem 21: 1-5.
- Koenders S.T.A., Rooden E.J. van, Elst H. van den, Florea B.I., Overkleeft H.S. & Stelt M. van der (2020), STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe, ChemBioChem 21: 1911-1917.
- Zhou J., Mock E.D., Al Ayed K., Di X., Kantae V., Burggraaff L., Stevens A.F., Martella A., Mohr F., Jiang M., Wel T. van der, Wendel T.J., Ofman T.P., Tran Y., Koster N. de, Westen G.J.P. van, Hankemeier T. & Stelt M. van der (2020), Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family, Journal of Medicinal Chemistry 63(17): 9340-9359.
- Sarott R.C., Westphal M.V., Pfaff P., Korn C., Sykes D.A., Gazzi T., Brennecke B., Atz K., Weise M., Mostinski Y., Hompluem P., Koers E., Miljuš T., Roth N.J., Asmelash H., Vong M.C., Piovesan J., Guba W., Rufer A.C., Kusznir E.A., Huber S., Raposo C., Zirwes E.A., Osterwald A., Pavlovic A., Moes S., Beck J., Benito-Cuesta I., Grande T., Ruiz de Martin Esteban S., Yeliseev A., Drawnel F., Widmer G., Holzer D., Wel T. van der, Mandhair H., Yuan C.Y., Drobyski W.R., Saroz Y., Grimsey N., Honer M., Fingerle J., Gawrisch K., Romero J., Hillard C.J., Varga Z.V., Stelt M. van der, Pacher P., Gertsch J., McCormick P.J., Ullmer C., Oddi S., Maccarrone M., Veprintsev D.B., Nazaré M., Grether U. & Carreira E.M. (2020), Development of high-specificity fluorescent probes to enable cannabinoid type 2 receptor studies in living cells, Journal of the American Chemical Society 142(40): 16953-16964.
- Baggelaar M.P., Dulk H. den, Florea B.I., Fazio D., Bernab Ograve N., Raspa M., Janssen A.P.A., Scavizzi F., Barboni B., Overkleeft H.S., Maccarrone M. & Stelt M. van der (2019), ABHD2 inhibitor identified by activity-based protein profiling reduces acrosome reaction, ACS Chemical Biology 14(10): 2295-2304.
- Janssen A.P.A., Hengst J.M.A. van, Béquignon O.J.M., Deng H., Westen G.J.P. van & Stelt M. van der (2019), Structure Kinetics Relationships and Molecular Dynamics Show Crucial Role for Heterocycle Leaving Group in Irreversible Diacylglycerol Lipase Inhibitors, Journal of Medicinal Chemistry 62(17): 7910-7922.
- Esbroeck A.C.M. van, Varga Z.V., Di X., Rooden E.J. van, Tóth V.E., Onódi Z., Kuśmierczyk M., Leszek P., Ferdinandy P., Hankemeier T., Stelt M. van der & Pacher P. (2019), Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system, Pharmacological Research 151: 104578.
- Koenders S.T.A., Wijaya L.S., Erkelens M.N., Bakker A.T., Noord V.E. van der, Rooden E.J. van, Burggraaff L., Putter P.C., Botter E., Wals K., Elst H. van den, Dulk H. den, Florea B.I., Water B. van de, Westen G.J.P. van, Mebius R.E., Overkleeft H.S., Le Dévédec S.E. & Stelt M. van der (2019), Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells, ACS Central Science 5(12): 1965-1974.
- Esbroeck A.C.M. van, Kantae V., Di X., Wel T. van der, Dulk J. den, Stevens A.F., Singh S., Bakker A.T., Florea B.I., Stella N., Overkleeft H.S., Hankemeier T. & Stelt M. van der (2019), Identification of alpha,beta-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells, Frontiers in Molecular Neuroscience 12: 286.
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- Marinelli S., Di Marzo V., Florenzano F., Fezza F., Viscomi M.T., Stelt M. van der, Bernardi G., Molinari M., Maccarrone Mauro & Mercuri N.B. (2007), N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors, Neuropsychopharmacology 32(2): 298-308.
- Wettschureck N., Stelt M. van der, Tsubokawa H., Krestel H., Moers A., Petrosino S., Schütz G., Di Marzo V. & Offermanns S. (2006), Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation, Molecular and Cellular Biology 26(15): 5888-5894.
- Stelt M. van der, Mazzola C., Esposito G., Matias I., Petrosino S., De Filippis D., Micale V., Steardo .L., Drago F., Iuvone T. & Di Marzo V. (2006), Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels, Cellular and Molecular Life Sciences 63(12): 1410-1424.
- Cascio M.G., Bisogno T., Palazzo E., Thomas A., Stelt M. van der, Brizzi A., De Novellis V., Marabese I., Ross R., Doelen T. van de, Brizzi V., Pertwee R., Maione S. & Di Marzo V. (2006), In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands, British Journal of Pharmacology 149(4): 431-440.
- Stelt M. van der, Fox S.H., Hill M., Crossman A.R., Petrosino S., Marzo V. di & Brotchie J.M. (2005), A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTPlesioned non-human primate models of Parkinson's disease, The FASEB Journal 19(7): 1140.
- Stelt M. van der & Marzo V. di (2005), Anandamide as an intracellular messenger regulating ion channel activity, Prostaglandins and Other Lipid Mediators 77(1-4): 111-122.
- Stelt M. van der, Trevisani M., Vellani V., Petrocellis L. de, Moriello A.S., Campi B., McNaughton P., Geppetti P. & Marzo V. di (2005), Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels, The EMBO Journal 24(17): 3026-3037.
- Stelt M. van der & Marzo V. di (2004), Endovanilloids - Putative endogenous ligands of transient receptor potential vanilloid 1 channels, European Journal of Biochemistry 271(10): 1827-1834.
- Ligresti A., Morera E., Stelt M. van der, Monory K., Lutz B., Ortar G. & Di Marzo V. (2004), Further evidence for the existence of a specific process for the membrane transport of anandamide, Biochemical Journal 380(1): 265-272.
- Stelt M. van der, Hansen H.H., Veldhuis W.B., Bär P.R., Nicolay K., Veldink G.A., Vliegenthart J.F. & Hansen H.S. (2003), Biosynthesis of endocannabinoids and their modes of action in neurodegenerative diseases, Neurotoxicity Research 5(3): 183-200.
- Stelt M. van der & Di Marzo V. (2003), The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders, European Journal of Pharmacology 480(1-3): 133-150.
- Veldhuis W.B., Stelt M. van der, Wadman M.W., Zadelhoff G. van, Maccarrone M., Fezza F., Veldink G.A., Vliegenthart J.F.G., Bar P.R., Nicolay K. & Di Marzo V. (2003), Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: Role of vanilloid receptors and lipoxygenases, Journal of Neuroscience 23(10): 4127-4133.
- Stelt M. van der, Veldhuis W.B., Wadman M.W., Zadelhoff G. van, Fezza F., Veldink G.A., Vliegenthart J.F.G., Bar P.R., Nicolay K. & Di Marzo V. (2003), Mechanisms underlying in vivo neuroprotection by the endocannabinoid anandamide and the cannabinoid/vanilloid receptor agonist, arvanil, Journal of Neurochemistry 85(s2): 6-6.
- Veldhuis W.B., Stelt M. van der, Delmas F., Gillet B., Veldink G.A., Vliegenthart J.F.G., Nicolay K. & Bar P.R. (2003), In vivo excitotoxicity induced by ouabain, a Na+/K+-ATPase inhibitor, Journal of Cerebral Blood Flow and Metabolism 23(1): 62-74.
- Marsicano G., Goodenough S., Monory K., Hermann H., Eder M., Cannich A., Azad S.C., Cascio M.G., Gutierrez S.O., Stelt M. van der, Lopez-Rodriguez M.L., Casanova E., Schutz G., Zieglgansberger W., Di Marzo V., Behl C. & Lutz B. (2003), CB1 cannabinoid receptors and on-demand defense against excitotoxicity, Science 302(5642): 84-88.
- Stelt M. van der, Kuik J.A. van, Bari M., Zadelhoff G. van, Leeflang B.R., Veldink G.A., Finazzi-Agro A., Vliegenthart J.F.G. & Maccarrone M. (2002), Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: Conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase, Journal of Medicinal Chemistry 45(17): 3709-3720.
- Stelt M. van der, Veldhuis W.B, Bar P.R., Veldink G.A, Vliegenthart J.F.G. & Nicolay K. (2001), Neuroprotection by Delta(9)-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity, Journal of Neuroscience 21(17): 6475-6479.
- Stelt M. van der, Veldhuis W.B., Haaften G.W. van, Fezza F., Bisogno T., Bar P.R., Veldink G.A., Vliegenthart J.F.G., Di Marzo V. & Nicolay K. (2001), Exogenous anandamide protects rat brain against acute neuronal injury in vivo, Journal of Neuroscience 21(22): 8765-8771.
- Stelt M. van der, Noordermeer M.A., Kiss T., Zadelhoff G. van, Merghart B., Veldink G.A. & Vliegenthart J.F.G. (2000), Formation of a new class of oxylipins from N-acyl(ethanol)amines by the lipoxygenase pathway, European Journal of Biochemistry 267(7): 2000-2007.
- Maccarrone M., Stelt M. van der, Rossi A., Veldink G.A., Vliegenthart J.F.G. & Agrio A.F. (1998), Anandamide hydrolysis by human cells in culture and brain, Journal of Biological Chemistry 273(48): 32332-32339.
- Stelt M. van der, Nieuwenhuizen W.F., Veldink G.A. & Vliegenthart J.F.G. (1997), Dioxygenation of N-linoleoyl amides by soybean lipoxygenase-1, FEBS Letters 411(2-3): 287-290.
- Stelt M. van der, Paoletti A.M., Maccarrone M., Nieuwenhuizen W.F., Bagetta G., Veldink G.A., Finazzi Agrò A. & Vliegenthart J.F.G. (1997), The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties, FEBS Letters 415(3): 313-316.
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