Sylvestre Bonnet
Hoogleraar Bioanorganische chemie
- Naam
- Prof.dr. S.A. Bonnet
- Telefoon
- +31 71 527 4260
- bonnet@chem.leidenuniv.nl
- ORCID iD
- 0000-0002-5810-3657
Meer informatie is beschikbaar op de Engelse profielpagina.
Promovendi
Nieuws
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Van bellenblaas tot brandstof: maakt dit bijzondere zeeplaagje binnenkort kunstmatige fotosynthese mogelijk? -
Zware metalen hebben slechte reputatie, maar genezen ook kanker -
Chemotherapie zonder bijwerkingen? Het kan, met licht -
Verlichting door licht: dit kankermedicijn vormt zelf nanodeeltjes -
Doorbraak kunstmatige fotosynthese dichterbij -
Drie nieuwe hoogleraren Leids Instituut voor Chemisch Onderzoek -
Nanodeeltjes en licht gaan de strijd aan met kanker -
De heilzame werking van licht -
Sylvestre Bonnet ontvangt ERC-subsidie voor chemotherapie geactiveerd door licht -
Met metalen en licht kankercellen doden -
Gaan zeep en zonlicht het energieprobleem oplossen? -
Vici voor Sylvestre Bonnet: nieuw licht op kankertherapie -
Zeven Leidse wetenschappers ontvangen Vici-beurs van 1,5 miljoen euro -
Ziektes detecteren met moleculen in het lichaam -
Op zoek naar betere medicijnen en behandelingen voor kanker -
Leiden viert tien jaar ERC -
Tien jaar ERC: Sylvestre Bonnet bestrijdt kanker met licht -
Medicijnen aanzetten met licht en vitamine C -
Leidse chemicus Bonnet over Nobelprijs scheikunde -
Sylvestre Bonnet lid van de Young Academy of Europe
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Twee promoties, één huwelijk, één dag en één onderzoeksgebied
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Leidse chemici ontvangen financiering voor onderzoek naar CO2-neutrale brandstoffen -
Leidse wetenschappers pakken kanker aan de basis aan -
Leids chemicus gaat kanker bestrijden met chemo en licht -
Zeven Vidi’s voor Leidse onderzoekers, waarvan drie voor onze faculteit
Hoogleraar Bioanorganische chemie
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Energy & Sustainability
- LIC/ES/Metal in Cat. Biom. & Inorg. Mat.
- Bretin L.R., Husiev Y., Vadde R., Zhang L., Hakkennes M.L.A., Abyar S., Johns A.C., Le Dévédec S.E., Betancourt T., Kornienko A. & Bonnet S.A. (2024), Red‐light activation of a microtubule polymerization inhibitor via amide functionalization of the ruthenium photocage, Angewandte Chemie (International Edition) 63(5): e202316425.
- Zhou X., Abyar S., Carbo-Bague I., Wang L., Türck S., Siegler M.A., Basu U., Ott I., Liu R., IJzerman A.P. & Bonnet S.A. (2024), Multitarget thiol-activated tetrapyridyl gold(III) complexes for hypoxic cancer therapy, CCS Chemistry 63(3): 783-797.
- Polanco Rivas E.A., Opdam L.V., Passerini L., Huber M.I., Bonnet S.A. & Pandit A. (2024), An artificial metalloenzyme that can oxidize water photocatalytically: design, synthesis, and characterization, Chemical Science 15(10): 3596-3609.
- Verbeet W., Husiev Y. & Bonnet S.A. (2024), Simple and efficient method for mono‐ and di‐amination of polypyridine N‐oxides, European Journal of Organic Chemistry 27(14): e202400054.
- Abyar S., Huang L., Husiev Y., Bretin L.R., Chau B., Vadde R., Wildeman J.H., Belfor K., Wijyay L.S., Noord V.E. van der, Harms A.C., Siegler M.A., Le Dévédec S.E. & Bonnet S.A. (2024), Oxygen-dependent interactions between the ruthenium cage and the photoreleased inhibitor in NAMPT-targeted photoactivated chemotherapy, Journal of Medicinal Chemistry 67(13): 11086–11102.
- Vadde R., Wijaya L.S., Beztsinna N., Griend C.J. van de, Water B. van de, Bonnet S.A. & Le Dévédec S.E. (2024), Cell viability imaging in tumor spheroids via DNA binding of a ruthenium(ii) light-switch complex, Chemical Communications 60(49): 6308-6311.
- Kaul N., Bergamasco L., Song H., Varkevisser T., Amati A., Falciani G., Rijn C.J.M. van, Chiavazzo E., Sen I., Bonnet S.A. & Hammarström L. (2024), Realizing symmetry-breaking architectures in soap films, Physical Review Letters 132(2): 028201.
- Andreeva V.D., Regeni I., Yang T., Elmanova A., Presselt M., Dietzek-Ivansic B. & Bonnet S.A. (2024), Red-to-blue triplet: triplet annihilation upconversion for calcium sensing, Journal of Physical Chemistry Letters 15: 7430-7435.
- Fiala J., Roach T., Holzinger A., Husiev Y., Delueg L., Hammerle F., Sanchez Armengolm E., Schöbel H., Bonnet S.A., Laffleur F., Kranner I., Lackner M. & Siewert B. (2024), The light-activated effect of natural anthraquinone parietin against candida auris and other fungal priority pathogens, Planta Medica 90(07/08): 588-594.
- Zhou X., Wang P., Vadde R., Zhang L., Jiang S., Li X., Abyar S., Papadopoulou P., Shao Y., Bretin L.R., Siegler M.A., Buda F., Kros A., Fan J., Peng X., Sun W. & Bonnet S.A. (2023), In vivo metallophilic self-assembly of a light-activated anticancer drug, Nature Chemistry 15: 980-987 (980-987).
- Hakkennes M.L.A., Meijer M.S., Menzel J.P., Goetz A.C., Duijn R. van, Siegler M.A., Buda F. & Bonnet S.A. (2023), Ligand rigidity steers the selectivity and efficiency of the photosubstitution reaction of strained ruthenium polypyridyl complexes, Journal of the American Chemical Society 145(24): 13420-13434.
- Zhang L., Wang P., Zhou X.Q., Bretin L.R., Zeng X., Husiev Y., Polanco Rivas E.A., Zhao G., Wijaya L.S., Biver T., Le Dévédec S.E., Sun W. & Bonnet S. (2023), Cyclic ruthenium-peptide conjugates as integrin-targeting phototherapeutic prodrugs for the treatment of brain tumors, Journal of the American Chemical Society 145(27): 14963-14980.
- Hammerle F., Fiala J., Höck A., Huymann L., Vrabl P., Husiev Y., Bonnet S., Peintner U. & Siewert B. (2023), Fungal anthraquinone photoantimicrobials challenge the dogma of Cationic photosensitizers, Journal of Natural Products 86(10): 2247-2257.
- Hakkennes M.L.A., Buda F. & Bonnet S.A. (2023), MetalDock: An Open Access Docking Tool for Easy and Reproducible Docking of Metal Complexes, Journal of Chemical Information and Modeling 63(24): 7816-7825.
- Andreeva V., Ehlers H., Reena Chandrababu A.K., Presselt M., Broek J. van den & Bonnet S.A. (2023), Combining nitric oxide and calcium sensing for the detection of endothelial dysfunction, Communications Chemistry 6(1): 179.
- Falciani G., Bergamasco L., Amati A., Verdoes G., Sen I., Bonnet S.A. & Chiavazzo E. (2023), Design and testing of a device for the characterization of gas transfer through soap films and measurement protocol based on color matching, International Communications in Heat and Mass Transfer 149: 107161.
- Bonnet S.A. (2023), Ruthenium-based photoactivated chemotherapy, Journal of the American Chemical Society 145(43): 23397-23415.
- Geest E.P. van, Götzfried S. K., Klein D. M., Salitra N., Popal S., Husiev Y., Griend C.J. van der, Zhou X., Siegler M. A., Schneider G.F. & Bonnet S.A. (2023), A Lock-and-Kill anticancer photoactivated chemotherapy agent: this article is part of a Special Issue celebrating the 50thAnniversary of the American Society for Photobiology, Photochemistry and Photobiology 99(2): 777-786.
- Binacchi F., Cassandra E., Cirri D., Griend C.J. van de, Zhou X., Messori L., Bonnet S.A., Pratesi A. & Biver T. (2023), A biophysical study of the interactions of palladium(II), platinum(II) and gold(III) complexes of aminopyridyl-2,2′-bipyridine ligands with RNAs and other nucleic acid structures, Dalton Transactions 52(3): 598-608.
- Timounay Y., Pannwitz A., Klein D.M., Biance A.L., Hoefnagel M.E., Sen I., Cagna A., Merrer M. le & Bonnet S.A. (2022), Interfacial characterization of ruthenium-based amphiphilic photosensitizers, Langmuir 38(31): 9697-9707.
- Flitsch S., Duboc C. & Bonnet S. (2022), New chemical tools for diagnosis and treatment of cancer, Journal of the American Chemical Society 2(5): 1018-1019.
- Chen Q., Cuello-Garibo J.A., Bretin L.R., Zhang L., Ramu V., Aydar Y., Batsiun Y., Bronkhorst S., Husiev Y., Beztsinna N., Chen L., Zhou X.Q., Schmidt C., Ott I., Jager M.J., Brouwer A.M., Snaar-Jagalska B.E. & Bonnet S.A. (2022), Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model, Chemical Science 13(23): 6899-6919.
- Rodríguez-Jiménez S., Song H., Lam E., Wright D., Pannwitz A., Bonke S.A., Baumberg J.J., Bonnet S.A., Hammarström L. & Reisner E. (2022), Self-assembled liposomes enhance electron transfer for efficient photocatalytic CO2 reduction, Journal of the American Chemical Society 144(21): 9399-9412.
- Griend C. van de, Vijver J.J.. van de, Siegler M.A. & Dame R.T. Bonnet S. (2022), Ruthenium-Locked Helical Chirality: A Barrier of Inversion and Formation of an Asymmetric Macrocycle, Inorganic Chemistry 61(40): 16045–16054.
- Klein D.M., Passerini L., Huber M.I. & Bonnet S.A. (2022), A stable alkylated cobalt catalyst for photocatalytic H2 generation in liposomes, ChemCatChem 14(20): e202200484.
- Song H., Amati A., Pannwitz A., Bonnet S. & Hammarström L. (2022), Mechanistic insights into the charge transfer dynamics of photocatalytic water oxidation at the lipid bilayer: water interface, Journal of the American Chemical Society 144(42): 19353-19364.
- Meijer M.S., Carlos R.S., Baptista M.S. & Bonnet S.A. (2022), Photomedicine with inorganic complexes: a bright future. In: Bahnemann D.W. & Patrocinio A.O.T. (red.), Springer handbook of inorganic photochemistry. Switzerland : Springer Nature . 1015-1033.
- Opdam L.V., Polanco Rivas E.A., Regt B. de, Lambertina N., Bakker C., Bonnet S.A. & Pandit A. (2022), A screening method for binding synthetic metallo-complexes to haem proteins, Analytical Biochemistry 653: 114788.
- Pannwitz A., Saaring H., Beztsinna N., Li X.M., Siegler M.A. & Bonnet S.A. (2021), Mimicking photosystem I with a transmembrane light harvester and energy transfer-induced photoreduction in phospholipid bilayers, Chemistry: a European Journal 27(9): 3013-3018.
- Zhou X.Q., Mytiliniou M., Hilgendorf J., Zeng Y., Papadopoulou P., Shao Y., Dominguez Maximilian P., Zhang L., Hesselberth M.B.S., Bos E., Siegler M.A., Buda F., Brouwer A.M., Kros A., Koning R.I., Heinrich D. & Bonnet S. (2021), Intracellular dynamic assembly of deep‐red emitting supramolecular nanostructures based on the Pt…Pt metallophilic interaction, Advanced Materials 33(37): 2008613.
- Liu C., Bos D. van den, Hartog B. den, Meij D. van der, Ramakrishnan A. & Bonnet S. (2021), Ligand controls the activity of light‐driven water oxidation catalyzed by nickel(II) porphyrin complexes in neutral homogeneous aqueous solutions, Angewandte Chemie - International Edition in English 60(24): 13463-13469.
- Busemann A., Flaspohler I., Zhou X.Q., Schmidt C., Götzfried S.K., Rixel V.H.S. van, Ott I., Siegler M.A. & Bonnet S.A. (2021), Ruthenium-based PACT agents based on bisquinoline chelates: synthesis, photochemistry, and cytotoxicity, Journal of Biological Inorganic Chemistry 26(6): 667-674.
- Dixon I.M., Bonnet S.A., Alary F. & Cuny J. (2021), Photoinduced ligand exchange dynamics of a polypyridyl ruthenium complex in aqueous solution, Journal of Physical Chemistry Letters 12(30): 7278-7284.
- Klein D.M., Rodriguez-Jimenez S., Hoefnagel M.E., Pannwitz A., Prabhakaran A., Siegler M.A., Keyes T.E., Reisner E., Brouwer A.M. & Bonnet S.A. (2021), Shorter alkyl chains enhance molecular diffusion and electron transfer kinetics between photosensitisers and catalysts in CO2-reducing photocatalytic liposomes, Chemistry: a European Journal 27(68): 17203-17212.
- Zhang J.D., Ramu V., Zhou X., Frias C., Ruiz-Molina D., Bonnet S.A., Roscini C. & Novio F. (2021), Photoactivable ruthenium-based coordination polymer nanoparticles for light-induced chemotherapy, Nanomaterials 11(11): 3089.
- Pannwitz A., Klein D.M., Rodriguez-Jimenez S., Casadevall C., Song H.W., Reisner E., Hammarstrom L. & Bonnet S.A. (2021), Roadmap towards solar fuel synthesis at the water interface of liposome membranes, Chemical Society Reviews 50(8): 4833-4855.
- Zhou X., Carbo-Bague I., Siegler M.A., Hilgendorf J., Basu U., Ott I., Liu R., Zhang L., Vadde R., IJzerman A.P. & Bonnet S.A. (2021), Rollover cyclometalation vs nitrogen coordination in Tetrapyridyl Anticancer Gold(III) complexes: effect on protein interaction and toxicity, JACS Au 1(4): 380-395.
- Klein D.M., Poortinga A., Verhoeven F.M., Bonn D., Bonnet S.A. & Rijn C.J.M. van (2021), Degradation of lipid based drug delivery formulations during nebulization, Chemical Physics 547: 111192.
- Vroegindeweij L.H.P., Wielopolski P.A., Boon A.J.W., Wilson J.H.P., Verdijk R.M., Zheng S.P., Bonnet S.A., Bossoni L., Weerd L. van der, Hernandez-Tamames J.A. & Langendonk J.G. (2021), MR imaging for the quantitative assessment of brain iron in aceruloplasminemia: a postmortem validation study, NeuroImage 245: 118752.
- Hammerle F., Steger L.M., Zhou X., Bonnet S.A., Huymann L., Peintner U. & Siewert B. (2021), Optimized isolation of 7,7′-biphyscion starting from Cortinarius rubrophyllus, a chemically unexplored fungal species rich in photosensitizers, Photochemical & Photobiological Sciences : .
- Kozsup M., Zhou X., Farkas E., Benyei A.C., Bonnet S.A., Patonay T., Konya K. & Buglyo P. (2021), Synthesis, characterization and cytotoxicity studies of Co(III)-flavonolato complexes, Journal of Inorganic Biochemistry 217: 111382.
- Zheng S., Spa S., Geest E.P. van, Ruitenbeek J.M. van & Bonnet S.A. (2021), Highly ordered, self-assembled monolayers of a spin-crossover complex with in-plane interactions, European Journal of Inorganic Chemistry 2021(28): 2814-2821.
- Geus M.A.R. de, Maurits E., Sarris A.J.C., Hansen T., Kloet M.S., Kamphorst K., Hoeve W. ten, Robillard M.S., Pannwitz A., Bonnet S.A., Codée J.D.C., Filippov D.V., Overkleeft H.S. & Kasteren S.I. van (2020), Fluorogenic Bifunctional Trans-cyclooctenes as Efficient Tools for Investigating Click-to-Release Kinetics, Chemistry: a European Journal 26(44): 9900-9904.
- Busemann A. Araman M.C. Flaspohler I. Pratesi A. Zhou X.Q. Rixel V.H.S. van Siegler M.A. Messori L. Kasteren S.I. van Bonnet S.A. (2020), Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies, Journal of Inorganic Chemistry 59(11): 7710-7720.
- Arias-Alpizar G., Kong L., Vlieg R.C., Rabe A., Papadopoulou P., Meijer M.S., Bonnet S., Vogel S., Noort J. van, Kros A. & Campbell F. (2020), Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo, Nature Communications 11: 3638.
- Geest E.P. van, Shakouri K., Fu W.Y., Robert V., Tudor V., Bonnet S.A. & Schneider G.F. (2020), Contactless spin switch sensing by chemo-electric gating of graphene, Advanced Materials 32(10): 1903575.
- Zhou X.Q., Xiao M., Ramu V., Hilgendorf J., Li X. Z., Papadopoulou P., Siegler M.A., Kros A., Sun W. & Bonnet S. (2020), The Self-Assembly of a Cyclometalated Palladium Photosensitizer into Protein-Stabilized Nanorods Triggers Drug Uptake In Vitro and In Vivo, Journal of the American Chemical Society 142(23): 10383-10399.
- Meijer M.S., Natile M.M. & Bonnet S.A. (2020), 796 nm Activation of a photocleavable ruthenium(II) complex conjugated to an upconverting nanoparticle through two phosphonate groups, Inorganic Chemistry 59(20): 14807-14818.
- Chen Q.C., Ramu V., Aydar Y., Groenewoud A., Zhou X.Q., Jager M.J., Cole H., Cameron C.G., McFarland S.A., Bonnet S. & Snaar-Jagalska B.E. (2020), TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models, Cancers 12(3): 587.
- Rixel V.H.S. van, Busemann A., Wissingh M.F., Hopkins S.L., Siewert B., Griend C.J. van de, Siegler M.A., Marzo T., Papi F., Ferraroni M., Gratteri P., Bazzicalupi C., Messori L. & Bonnet S.A. (2019), Induction of a Four‐Way Junction Structure in the DNA Palindromic Hexanucleotide 5′‐d(CGTACG)‐3′ by a Mononuclear Platinum Complex, Angewandte Chemie 131(28): 9478-9482.
- Cuello-Garibo J.A., James C.C., Siegler M.A., Hopkins S.L. & Bonnet S.A. (2019), Selective Preparation of a Heteroleptic Cyclometallated Ruthenium Complex Capable of Undergoing Photosubstitution of a Bidentate Ligand, Chemistry: a European Journal 25(5): 1260-1268.
- Lameijer L.N., Griend C.J. van de, Hopkins S.L., Volbeda A.G., Askes S.H.C., Siegler M.A. & Bonnet S.A. (2019), Photochemical Resolution of a Thermally Inert Cyclometalated Ru(phbpy)(N–N)(Sulfoxide)+ Complex, Journal of the American Chemical Society 141(1): 352-362.
- Ramu V., Reddy G., Liu J., Hoffmann P., Sollapur R., Wyrwa R., Kupfer S., Spielmann C., Bonnet S.A., Neugebauer U. & Schiller A. (2019), Two‐Photon‐Induced CO‐Releasing Molecules as Molecular Logic Systems in Solution, Polymers, and Cells, Chemistry: a European Journal 25(36): 8453-8458.
- Zhou X.-Q., Busemann A., Meijer M.S., Siegler M.A. & Bonnet S.A. (2019), The two isomers of a cyclometallated palladium sensitizer show different photodynamic properties in cancer cells, Chemical Communications 55(32): 4695-4698.
- Meijer M.S., Saez Talens V., Hilbers M.F., Kieltyka R.E., Brouwer A.M., Natile M.M. & Bonnet S.A. (2019), NIR-Light-Driven Generation of Reactive Oxygen Species Using Ru(II)-Decorated Lipid-Encapsulated Upconverting Nanoparticles, Langmuir 35(37): 12079−12090.
- Badiani V., Bajada M., Beller M., Bocarsly A.B., Bonnet S.A., Bozal-Ginesta C., Brueggeller P., Butt J.N., Cassiola F., Grätzel M., Hammarström L., Hatzell M.C., Jeuken L.J.C., König B., Kuehnel M.F., Lawrence J., Lee C.Y., Maneiro M., Minteer S.D., Moore E.E., Piper S.E.H., Plumeré N., Reek J.N.H., Reisner E., Roy S., Shears J., Shylin S.I., Soo H.S., Wagner A., Wielend D., Zhang J. & Zwijnenburg M. (2019), Biological approaches to artificial photosynthesis: general discussion, Faraday Discussions 215: 66-83.
- Meijer M.S. & Bonnet S.A. (2019), Diastereoselective Synthesis and Two-Step Photocleavage of Ruthenium Polypyridyl Complexes Bearing a Bis(thioether) Ligand, Inorganic Chemistry 58(17): 11689-11698.
- Rixel V.H.S. van, Ramu V., Auyeung A.B., Beztsinna N., Leger D.Y., Lameijer L.N., Hilt S.T., Le Devedec S.E., Yildiz T., Betancourt T., Gildner M.B., Hudnall T.W., Sol V., Liagre B., Kornienko A. & Bonnet S. (2019), Photo-Uncaging of a Microtubule-Targeted Rigidin Analogue in Hypoxic Cancer Cells and in a Xenograft Mouse Model, Journal of the American Chemical Society 141(46): 18444-18454.
- Rixel V.H.S. van, Busemann A., Wissingh M.F., Hopkins S.L., Siewert B., Griend C. van de, Siegler M.A., Marzo T., Papi F., Ferraroni M., Gratteri P., Bazzicalupi C., Messori L. & Bonnet S.A. (2019), Induction of a four-way junction structure in the DNA palindromic hexanucleotide 5 '-d(CGTACG)-3 ' by a mononuclear platinum complex, Angewandte Chemie (International Edition) 58(28): 9378-9382.
- Siewert B., Hammerle F., Bingger I., Peintner U., Pannwitz A., Bonnet S.A. & Stuppner H. (2019), Mushrooms - an unrevealed source for promising photopharmaceuticals, Planta Medica 85(18): 1418.
- Anton-Garcia D., Apfel U.-P., Andrei V., Aitchison C.M., Badiani V., Beller M., Bocarsly A.B., Bonnet S.A., Brüggeller P., Caputo C.A., Cassiola F., Clausing S., Cooper A.I., Creissen C.E., Pena O'Shea V.A. de la, Domcke W., Durrant J.R., Grätzel M., Hammarström L., Hankin A., Hatzell M.C., Karadas F., König B., Kuehnel M.F., Lamaison S., Lin C.-Y., Maneiro M., Minteer S.D., Paris A.R., Pastor E., Pornrungroj C., Reek J.N.H., Reiser E., Roy S., Sahm C., Sankar R., Shaw W., Shylin S.I., Smith W.A., Sokol K., Soo H., Sprick R.S., Viertl W., Vogel A., Wagner A., Wakerley D, Wang Q., Wielend D. & Zwijnenburg M.A. (2019), Synthetic approaches to artificial photosynthesis: general discussion, Faraday Discussions 215: 242-281.
- Lameijer L.N., Brevé T.G., Rixel V.H.S. van, Askes S.H.C., Siegler M.A. & Bonnet S.A. (2018), Effects of the Bidentate Ligand on the Photophysical Properties, Cellular Uptake, and (Photo)cytotoxicity of Glycoconjugates Based on the [Ru(tpy)(NN)(L)]2+ Scaffold, Chemistry: a European Journal 24(11): 2709-2717.
- Rixel V.H.S. van, Moolenaar G.F., Siegler M.A., Messori L. & Bonnet S. (2018), Controlling with light the interaction between trans-tetrapyridyl ruthenium complexes and an oligonucleotide, Dalton Transactions 47(2): 507-516.
- Askes S.H.C., Bossert N., Bussmann J., Talens V.S., Meijer M.S., Kieltyka R.E., Kros A., Bonnet S.A. & Heinrich D.M. (2018), Dynamics of dual-fluorescent polymersomes with durable integrity in living cancer cells and zebrafish embryos, Biomaterials 168: 54-63.
- Lameijer L.N., Roy J.L. le, Vorm S. van der & Bonnet S.A. (2018), Synthesis of O-1-O-6 Substituted Positional Isomers of D-Glucose-Thioether Ligands and Their Ruthenium Polypyridyl Conjugates, Journal of Organic Chemistry (JOC) 83(21): 12985-12997.
- Siewert B., Langerman M., Pannwitz A. & Bonnet S.A. (2018), Synthesis and Avidin Binding of Ruthenium Complexes Functionalized with a Light-Cleavable Free Biotin Moiety, European Journal of Inorganic Chemistry 2018(37): 4117-4124.
- Sun W., Wen Y., Thiramanas R., Chen M., Han J., Gong N., Wagner M., Jiang S., Meijer M.S., Bonnet S., Butt H.J., Mailaender V., Liang X.J. & Wu S. (2018), Red-Light-Controlled Release of Drug-Ru Complex Conjugates from Metallopolymer Micelles for Phototherapy in Hypoxic Tumor Environments, Advanced Functional Materials 28(39): 1804227.
- Meijer M.S., Rojas-Gutierrez P.A., Busko D., Howard I.A., Frenze F., Wuerth C., Resch-Genger U., Richards B.S., Turshatov A., Capobianco J.A. & Bonnet S. (2018), Absolute upconversion quantum yields of blue- emitting LiYF4: Yb3+, Tm3+upconverting nanoparticles, Physical Chemistry Chemical Physics 20(35): 22556-22562.
- Lopez Mora N.L., Gao Y., Gutierrez M.G., Peruzzi J., Bakker I., Peters R.J.R.W., Siewert B., Bonnet S.A., Kieltyka R.E., Hest J.C.M. van, Malmstadt N. & Kros A. (2017), Evaluation of dextran(ethylene glycol) hydrogel films for giant unilamellar lipid vesicle production and their application for the encapsulation of polymersomes, SOFT MATTER 13(33): 5580-5588.
- Siewert B., Langerman M., Hontani Y., Kennis J.T.M., Rixel V.H.S. van, Limburg B., Siegler M.A., Saez Talens V., Kieltyka R.E. & Bonnet S.A. (2017), Turning on the red phosphorescence of a [Ru(tpy)(bpy)(Cl)]Cl complex by amide substitution: self- aggregation, toxicity, and cellular localization of an emissive ruthenium-based amphiphile, Chemical Communications 53: 11126-11129.
- Askes S.H.C., Leeuwenburgh V.C., Pomp W., Arjmandi-Tash H., Tanase S., Schmidt T. & Bonnet S.A. (2017), Water-Dispersible Silica-Coated Upconverting Liposomes: Can a Thin Silica Layer Protect TTA-UC against Oxygen Quenching?, ACS Biomaterials Science and Engineering 3(3): 322-334.
- Askes S.H.C., Reddy G.U., Wyrwa R., Bonnet S.A. & Schiller A. (2017), Red Light-Triggered CO Release from Mn-2(CO)10 Using Triplet Sensitization in Polymer Nonwoven Fabrics, Journal of the American Chemical Society 139(43): 15292-15295.
- Lameijer L.N., Ernst D., Hopkins S.L., Meijer M.S., Askes S.H.C., Le Dévédec S.E. & Bonnet S.A. (2017), A Red-Light-Activated Ruthenium-Caged NAMPT Inhibitor Remains Phototoxic in Hypoxic Cancer Cells, Angewandte Chemie (International Edition) 56(38): 11549-11553.
- Askes S.H.C., Brodie P., Bruylants G. & Bonnet S.A. (2017), Temperature Dependence of Triplet-Triplet Annihilation Upconversion in Phospholipid Membranes, The Journal of Physical Chemistry B 121(4): 780-786.
- Lameijer L.N., Hopkins S.L., Brevé T.G., Askes S.H.C. & Bonnet S.A. (2016), d- Versus l-Glucose Conjugation: Mitochondrial Targeting of a Light-Activated Dual-Mode-of-Action Ruthenium-Based Anticancer Prodrug, Chemistry: a European Journal 22: .
- Kong L., Askes S.H.C., Bonnet S.A., Kros A. & Campbell F. (2016), Temporal Control of Membrane Fusion through photolabile PEGylation of liposome membranes, Angewandte Chemie (International Edition) 55(4): 1396-1400.
- Zheng S., Reintjens N.R.M., Siegler M.A., Roubeau O., Bouwman E., Rudavskyi A., Havenith R.W.A. & Bonnet S. (2016), Stabilization of the Low-Spin State in a Mononuclear Iron(II) Complex and High-Temperature Cooperative Spin Crossover Mediated by Hydrogen Bonding, Chemistry: a European Journal 22(1): 331-339.
- Rixel V.H.S. van, Siewert B., Hopkins S.L., Askes S.H.C., Busemann A., Siegler M.A. & Bonnet S.A. (2016), Green light-induced apoptosis in cancer cells by a tetrapyridyl ruthenium prodrug offering two trans coordination sites, Chemical Science 7(8): 4922-4929.
- Gottle A.J., Alary F., Boggio-Pasqua M., Dixon I.M., Heully J.-L., Bahreman A., Askes S.H.C. & Bonnet S.A. (2016), Pivotal Role of a Pentacoordinate (MC)-M-3 State on the Photocleavage Efficiency of a Thioether Ligand in Ruthenium(II) Complexes: A Theoretical Mechanistic Study, Inorganic Chemistry 55(9): 4448-4456.
- Hernandez E., Zheng S., Shepherd H., Yufit D., Ridier K., Bedoui S., Nicolazzi W., Velazquez V., Bonnet S., Molnár G. & Bousseksou A. (2016), Spatially resolved investigation and control of the bistability in single crystals of the [Fe(bbpya)(NCS)2] spin crossover complex, The Journal of Physical Chemistry Part C 120(48): 27608.
- Askes S.H.C., Meijer M.S., Bouwens T., Landman I. & Bonnet S.A. (2016), Red light activation of Ru(II) polypyridyl prodrugs via triplet-triplet annihilation upconversion: feasibility in air and through meat, Molecules 21: 1460.
- Hopkins S.L., Siewert B., Askes S.H.C., Veldhuizen P., Zwier R., Heger M. & Bonnet S.A. (2016), An in vitro cell irradiation protocol for testing photopharmaceuticals and the effect of blue, green, and red light on human cancer cell lines, Photochemical & Photobiological Sciences 15(5): 644-653.
- Limburg B., Bouwman E. & Bonnet S.A. (2016), Effect of Liposomes on the Kinetics and Mechanism of the Photocatalytic Reduction of Methyl Viologen, The Journal of Physical Chemistry B 120(28): 6969-6975.
- Limburg B., Wermink J., Nielen S.S. van, Kortlever R., Koper M.T.M., Bouwman E. & Bonnet S. (2016), Kinetics of photocatalytic water oxidation at liposomes: membrane anchoring stabilizes the photosensitizer, ACS Catalysis 6(9): 5968-5977.
- Limburg B., Bouwman E. & Bonnet S.A. (2016), Rate and stability of photocatalytic water oxidation using [Ru(bpy)(3)](2+) as photosensitizer, ACS Catalysis 6(8): 5273-5284.
- Askes S.H.C., Pomp W., Hopkins S.L., Kros A., Wu S., Schmidt T. & Bonnet S.A. (2016), Imaging upconverting polymersomes in cancer cells: biocompatible anti-oxidants brighten triplet-triplet annihilation upconversion, Small 12(40): 5579-5590.
- Siewert B., Rixel V.H.S. van, Rooden E.J. van, Hopkins S.L., Moester M.J.B., Ariese F., Siegler M.A. & Bonnet S.A. (2016), Chemical Swarming: Depending on Concentration, an Amphiphilic Ruthenium Polypyridyl Complex Induces Cell Death via Two Different Mechanisms, Chemistry: a European Journal 22(31): 10960-10968.
- Limburg B., Bouwman E. & Bonnet S.A. (2015), Catalytic photoinduced electron transport across a lipid bilayer mediated by a membrane-soluble electron relay, Chemical Communications 51(96): 17128-17131.
- Rixel V.H.S. van, Busemann A., Gottle A.J. & Bonnet S.A. (2015), Preparation, stability, and photoreactivity of thiolato ruthenium polypyridyl complexes: Can cysteine derivatives protect ruthenium-based anticancer complexes?, Journal of Inorganic Biochemistry 150: 174-181.
- Bedoui S., Nicolazzi W., Zheng S., Bonnet S., Molnar G. & Bousseksou A. (2015), Impact of single crystal properties on nucleation and growth mechanisms of a spin transition, Polyhedron 87: 411-416.
- Askes S.H.C., López Mora N., Harkes R., Koning R.I., Koster B., Schmidt T., Kros A. & Bonnet S.A. (2015), Imaging the lipid bilayer of giant unilamellar vesicles using red-to-blue light upconversion, Chemical Communications 51(44): 9137-9140.
- Bonnet S.A. (2015), Shifting the Light Activation of Metallodrugs to the Red and Near-Infrared Region in Anticancer Phototherapy, Comments on Inorganic Chemistry 35(4): 179-213.
- Askes S.H.C., Kloz M., Bruylants G., Kennis J.T.M. & Bonnet S.A. (2015), Triplet-triplet annihilation upconversion followed by FRET for the red light activation of a photodissociative ruthenium complex in liposomes, Physical Chemistry Chemical Physics 17: 27380-27390.
- Askes S.H.C. & Bonnet S. (30 april 2015), Upconverting vesicles and uses (octrooi nr. WO 2015/059180 A2). Universiteit Leiden. [octrooi].
- Zheng S., Siegler M.A., Roubeau O. & Bonnet S. (2014), Influence of Selenocyanate Ligands on the Transition Temperature and Cooperativity of bapbpy-Based Fe(II) Spin-Crossover Compounds, Inorganic Chemistry 53(24): 13162-13173.
- Ording-Wenker E.C.M., Plas M. van der, Siegler M.A., Bonnet S.A., Bickelhaupt F.M., Guerra C.F. & Bouwman E. (2014), Thermodynamics of the Cu-II mu-Thiolate and Cu-I Disulfide Equilibrium: A Combined Experimental and Theoretical Study, Inorganic Chemistry 53(16): 8494-8504.
- Siewert B., Rixel V.H.S. van, Bahreman A., Higgins S.L.H., Heger M., Askes S.H.C. & Bonnet S.A. (2014), Biological evaluation of light-activatable ruthenium-based anticancer prodrugs, Journal of Biological Inorganic Chemistry 19: S784-S784.
- Askes S.H.C., Bahreman A. & Bonnet S. (2014), Activation of a Photodissociative Ruthenium Complex by Triplet-Triplet Annihilation Upconversion in Liposomes, Angewandte Chemie - International Edition in English 53(4): 1029-1033.
- Limburg B., Laisne G., Bouwman E. & Bonnet S. (2014), Enhanced Photoinduced Electron Transfer at the Surface of Charged Lipid Bilayers, Chemistry: a European Journal 20(29): 8965-8972.
- Bahreman A., Cuello-Garibo J.A. & Bonnet S. (2014), Yellow-light sensitization of a ligand photosubstitution reaction in a ruthenium polypyridyl complex covalently bound to a rhodamine dye, Dalton Transactions 43(11): 4494-4505.
- Bonnet S., Askes S.H.C., Bahreman A. & Cuello-Garibo J.A. (2014), Light activation of anticancer metallodrugs with blue, yellow, and red photons, Journal of Biological Inorganic Chemistry 19: S713-S713.
- Grasso G. & Bonnet S. (2014), Metal complexes and metalloproteases: targeting conformational diseases, Metallomics 6(8): 1346-1357.
- Bahreman A., Rabe M., Kros A., Bruylants G. & Bonnet S. (2014), Binding of a Ruthenium Complex to a Thioether Ligand Embedded in a Negatively Charged Lipid Bilayer: A Two-Step Mechanism, Chemistry: a European Journal 20(24): 7429-7438.
- Schmidt Sven Olaf, Kisslinger Sandra, Wuertele Christian, Bonnet Sylvestre, Schindler Siegfried & Tuczek Felix (2013), Iron(II) Complexes Supported by a Tetradentate Ligand Providing a Strained Equatorial Coordination Environment: Geometric and Electronic-Structural Implications, Zeitschrift fuer Anorganische und Allgemeine Chemie 639(15): 2774-2778.
- Zheng S., Sieger M.A., Sanchez Costa J., Fu W.T. & Bonnet S. (2013), Effect of Metal Dilution on the Thermal Spin Transition of [FexZn1-x(bapbpy)(NCS)(2)], European Journal of Inorganic Chemistry (5-6): 1033-1042.
- Gamba I., Mutikainen I., Bouwman E., Reedijk J. & Bonnet S. (2013), Synthesis and Characterization of Copper Complexes of a Tetrapyridyl Ligand, and Their Use in the Catalytic Aerobic Oxidation of Benzyl Alcohol, European Journal of Inorganic Chemistry 2013(1): 115-123.
- Bahreman A., Limburg B., Siegler M.A., Bouwman E. & Bonnet S.A. (2013), Spontaneous Formation in the Dark, and Visible Light-Induced Cleavage, of a Ru-S Bond in Water: A Thermodynamic and Kinetic Study, Inorganic Chemistry 52(16): 9456-9469.
- Molenbroek E., Straathof N., Dueck S., Rashid Z., Van Lenthe J.H., Lutz M., Gandubert A., Klein Gebbink R.J.M., De Cola L. & Bonnet S. (2013), Zinc coordination to the bapbpy ligand in homogeneous solutions and at liposomes: zinc detection via fluorescence enhancement, Dalton Transactions 42(8): 2973-2984.
- Limburg B., Bouwman E. & Bonnet S. (2012), Molecular water oxidation catalysts based on transition metals and their decomposition pathways, Coordination Chemistry Reviews 256(15-16): .
- Bedoui S., Lopes M., Zheng S., Bonnet S., Molnar G. & Bousseksou A. (2012), Laser-Induced Artificial Defects (LIADs): Towards the Control of the Spatiotemporal Dynamics in Spin Transition Materials, Advanced Materials 24(18): .
- Pillet S., Bendeif E., Bonnet S., Shepherd H.J. & Guionneau P. (2012), Multimetastability, phototrapping, and thermal trapping of a metastable commensurate superstructure in a Fe(II) spin-crossover compound, PHYSICAL REVIEW B 86(6): 064106.
- Bedoui S., Lopes M., Nicolazzi W., Bonnet S.A., Zheng S., Molnar G. & Bousseksou A. (2012), Triggering a Phase Transition by a Spatially Localized Laser Pulse: Role of Strain, Physical Review Letters 109(13): 135702.
- Bahreman A., Limburg B., Siegler M.A., Koning R., Koster A.J. & Bonnet S. (2012), Ruthenium Polypyridyl Complexes Hopping at Anionic Lipid Bilayers through a Supramolecular Bond Sensitive to Visible Light, Chemistry: a European Journal 18(33): .
- Kisslinger S., Kelm H., Zheng S.P., Beitat A., Wurtele C., Wortmann R., Bonnet S., Herres-Pawlis S., Kruger H.J. & Schindler S. (2012), Synthesis and Characterization of Iron(II) Thiocyanate Complexes with Derivatives of the Tris(pyridine-2-ylmethyl)amine (tmpa) Ligand, Zeitschrift fuer Anorganische und Allgemeine Chemie 638(12-13): .
- Contreras Carballada P., Mourtzis N., Felici M., Bonnet S., Nolte R.J.M., Williams R.M., Cola L. de & Feiters M.C. (2012), Variation of the viologen electron relay in cyclodextrin-based self-assembled systems for photoinduced hydrogen evolution from water, European Journal of Organic Chemistry 34(34): 6729-6736.
- Bonnet S. (26 april 2012), Light induced drug release (octrooi nr. WO 2012/052821). Verleend op 26 april 2012 door USPTO. [octrooi].
- Bonnet S., Limburg B., Meeldijk J.D., Klein Gebbink R.J.M. & Killian J.A. (2011), Ruthenium-Decorated Lipid Vesicles: Light-Induced Release of Ru(terpy)(bpy)(OH2)2+ and Thermal Back Coordination, Journal of the American Chemical Society 133(2): .
- Arcis-Castíllo Zulema, Zheng Sipeng, Siegler Maxime A., Roubeau Olivier, Bedoui Salma & Bonnet Sylvestre (2011), Tuning the Transition Temperature and Cooperativity of bapbpy-Based Mononuclear Spin-Crossover Compounds: Interplay between Molecular and Crystal Engineering, Chemistry: a European Journal 17(52): .
- Bonnet S., Van Lenthe J.H., Van Dam H.J.J., Van Koten G. & Klein Gebbink R.J.M. (2011), SO2-binding properties of cationic h6,h1-NCN-pincer arene ruthenium platinum complexes: spectroscopic and theoretical studies, Dalton Transactions 40(11): 2542-2548.
- Shepherd H.J., Bonnet S.A., Guionneau P., Bedoui S., Garbarino G., Nicolazzi W., Bousseksou A. & Molnar G. (2011), Pressure-induced two-step spin transition with structural symmetry breaking: X-ray diffraction, magnetic, and Raman studies, PHYSICAL REVIEW B 84(14): 144107.
- Goldbach R.E., Rodriguez-Garcia I., Van Lenthe J.H., Siegler M.A. & Bonnet S. (2011), N-Acetylmethionine and Biotin as Photocleavable Protective Groups for Ruthenium Polypyridyl Complexes, Chemistry: a European Journal 17(36): .
- Siegler M.A., Bonnet S., Schreurs A.M.M., Gebbink R.J.M.K., Van Koten G. & Spek A.L. (2010), On the Two Closely Related Phases of [Ru(C5Me5) (eta(6)-1,3-(Me2NCH2)(2)C6H4)](BF4) and the Reversible Solid-Solid Order-Disorder Phase Transition, Journal of Chemical Crystallography 40(9): .
- Bedoui S., Molnar G., Bonnet S., Quintero C., Shepherd H.J., Nicolazzi W., Salmon L. & Bousseksou A. (2010), Raman spectroscopic and optical imaging of high spin/low spin domains in a spin crossover complex, Chemical Physics Letters 499(1-3): .
- Kepenekian M., Costa J.S., Le Guennic B., Maldivi P., Bonnet S.A., Reedijk J., Gamez P. & Robert V. (2010), Reliability and Storage Capacity: a Compromise Illustrated in the Two-Step Spin-Crossover System [Fe(bapbpy)(NCS)(2)], Inorganic Chemistry 49(23): 11057-11061.
- Bonnet S.A., Siegler M.A., Lenthe J.H. van, Lutz M., Spek A.L., Koten G. & Klein Gebbink R.J.M. (2010), Ruthenium-to-Platinum Interactions in eta(6),eta(1) NCN-Pincer Arene Heterobimetallic Complexes: An Experimental and Theoretical Study, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY 2010(29): 4667-4677.
- Bonnet S.A., Lutz M., Spek A.L., Koten G. van & Klein Gebbink R.J.M. (2010), Bimetallic eta(6),eta(1) SCS- and PCP-pincer ruthenium palladium complexes: synthesis, structure, and catalytic activity, Organometallics 29(5): 1157-2267.
- Bonnet S., Molnar G., Costa J., Siegler M.A., Spek A., Bousseksou A., Fu W.T., Gamez P. & Reedijk J. (2009), Influence of Sample Preparation, Temperature, Light, and Pressure on the Two-Step Spin Crossover Mononuclear Compound [Fe(bapbpy)(NCS)2], Chemistry of Materials 21(6): 1123-1136.
- Bonnet S., Li J., Siegler M.A., Chrzanowski L.S. von der, Spek A.L., Koten G. van & Klein Gebbink R.J.M. (2009), Synthesis and Resolution of Planar-Chiral Ruthenium-Palladium Complexes with ECE ' Pincer Ligands, Chemistry: a European Journal 15(14): 3340-3343.
- Bonnet S., Siegler M.A., Costa J.S., Molnar G., Bousseksou A., Spek A.L., Gamez P. & Reedijk J. (2008), A two-step spin crossover mononuclear iron(II) complex with a [HS-LS-LS] intermediate phase, Chemical Communications 2008(43): 5619-5621.