Gijs van der Marel
Emeritus hoogleraar Synthetische organische chemie
- Naam
- Prof.dr. G.A. van der Marel
- Telefoon
- +31 71 527 2727
- marel_g@chem.leidenuniv.nl
- ORCID iD
- 0000-0001-8917-3458
Meer informatie is beschikbaar op de Engelse profielpagina.
Promovendi
Nieuws
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Europese samenwerking werpt licht op het ontdekken van industriële enzymen -
Kistemaker promoveert cum laude op productie baanbrekende moleculen -
TOP-PUNT subsidie voor chemicus Gijs van der Marel -
Slimme medicijnen stap dichterbij -
Vier grote subsidies voor excellente Leidse onderzoekers in de chemie -
Leiden Institute of Chemistry sleept vier NWO ECHO subsidies binnen
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In memoriam Professor dr. Jan Cornelisse
Emeritus hoogleraar Synthetische organische chemie
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Bio-organic Synthesis
- Minnee H., Rack J.G.M., Marel G.A. van der, Overkleeft H.S., Codée J.D.C., Ahel I. & Filippov D.V. (2024), Solid-phase synthesis and biological evaluation of peptides ADP-Ribosylated at histidine, Angewandte Chemie (International Edition) 63(4): e202313317.
- Remmerswaal W.A., Elferink H., Houthuijs K.J., Hansen T., Braak F. ter, Berden G., Vorm S. van der, Martens J., Oomens J., Marel G.A. van der, Boltje T.J. & Codee J.D.C. (2024), Anomeric triflates versus dioxanium ions: different product-forming intermediates from 3-Acyl benzylidene mannosyl and glucosyl donors, Journal of Organic Chemistry (JOC) 89(3): 1618-1625.
- Remmerswaal W.A., Hoogers D., Hoopman M.J., Marel G.A. van der & Codee J.D.C. (2024), The influence of acceptor acidity on hydrogen bond mediated aglycone delivery (HAD) through the picoloyl protecting group, European Journal of Organic Chemistry 27(7): e202301063.
- Ofman T.P., Heming J.J.A., Nin-Hill A., Küllmer F., Moran E., Bennett M., Steneker R., Klein A.M., Ruijgrok G., Kok K., Armstrong Z.W.B., Aerts J.M.F.G., Marel G.A. van der, Rovira C., Davies G.J., Artola M.E., Codée J.D.C. & Overkleeft H.S. Rovira Carme Davies Gideon J. Artola Marta Codée Jeroen D. C. Overkleeft Herman S. (2024), Conformational and electronic variations in 1,2‐ and 1,5a‐Cyclophellitols and their impact on retaining α‐glucosidase inhibition, Chemistry: a European Journal 30(31): e202400723.
- Artola Perez de Azanza M.E., Aerts J.M.F.G., Marel G.A. van der, Rovira C., Codee J.D.C., Davies G.J. & Overkleeft H.S. (2024), From mechanism-based retaining glycosidase inhibitors to activity-based glycosidase profiling, Journal of the American Chemical Society 146(36): 24729-24741.
- Ofman T.P., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2023), Design and synthesis of exocyclic cyclitol aziridines as potential mechanism-based glycosidase inactivators, European Journal of Organic Chemistry 26(16): e202300186.
- Minnee H., Chung H.W., Rack J.G.M., Marel G.A. van der, Overkleeft H.S., Codee J.D.C., Ahel I. & Filippov D.V. (2023), Four of a kind: a complete collection of ADP-ribosylated histidine isosteres using Cu(I)- and Ru(II)-catalyzed click chemistry, Journal of Organic Chemistry (JOC) 88(15): 10801-10809.
- Kuo C.L., Su Q., Nieuwendijk A.M.C.H. van den, Beenakker T.J.M., Offen W.A., Willems L.I., Boot R.G., Sarris A.J.C., Rosa Alcalde Marques A.R.A., Codée J.D.C., Marel G.A. van der, Florea B.I., Davies G.J., Overkleeft H.S. & Aerts J.M.F.G. (2023), The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe, Organic and Biomolecular Chemistry 21(38): 7813-7820.
- Wang Z., Poveda A., Zhang Q., Unione L., Overkleeft H.S., Marel G.A. van der, Jesus J.B. & Codee J.D.C. (2023), Total synthesis and structural studies of zwitterionic Bacteroides fragilis polysaccharide A1 fragments, Journal of the American Chemical Society 145(25): 14052-14063.
- Madern J.M., Voorneveld J., Rack J.G.M., Kistemaker H.A.V., Ahel I., Marel G.A. van der, Codee J.D.C. & Filippov D.V. (2023), 4-thioribose analogues of adenosine diphosphate ribose (ADPr) peptides, Organic Letters 25(27): 4980-4984.
- Hengst J.M.A. van, Hellemons R.J.C., Remmerswaal W.A., Vrande K.N.A. van de, Hansen T., Vorm S. van der, Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2023), Mapping the effect of configuration and protecting group pattern on glycosyl acceptor reactivity, Chemical Science 14(6): 1532-1542.
- Ishizuka S., Dijk J.H.M. van, Kawakita T., Miyamoto Y., Maeda Y., Goto M., Le Calvez G., Groot L.M., Witte M.D., Minnaard A.J., Marel G.A. van der, Ato M., Nagae M., Codee J.D.C. & Yamasaki S. (2023), PGL-III, a rare intermediate of Mycobacterium leprae phenolic glycolipid biosynthesis, is a potent Mincle ligand, ACS Central Science 9(7): 1388-1399.
- Gelder M.A., Zanden S.Y. van der, Vriends M.B.L., Wagensveld R.A., Marel G.A. van der, Codee J.D.C., Overkleeft H.S., Wander D.P.A. & Neefjes J.J.C. (2023), Re-exploring the anthracycline chemical space for better anti-cancer compounds, Journal of Medicinal Chemistry 66(16): 11390–11398.
- Males A., Kok K., Nin-Hill A., Koster N. de, Beukel S. van den, Beenakker T.J.M., Marel G.A. van der, Codée J.D.C., Aerts J.M.F.G., Overkleeft H.S., Rovira C., Davies G. & Artola Perez de Azanza M.E. (2023), Trans-cyclosulfamidate mannose-configured cyclitol allows isoform-dependent inhibition of GH47 α-d-mannosidases through a bump–hole strategy, Chemical Science 14(46): 13581-13586.
- Wang Z., Gimeno A., Lete M.G., Overkleeft H.S., Marel G.A., Chiodo F., Jiménez-Barbero J. & Codée J.D.C. (2023), Synthetic zwitterionic streptococcus pneumoniae Type 1 oligosaccharides carrying labile O-acetyl esters, Angewandte Chemie (International Edition) 62(1): e202211940.
- Kok K., Kuo C.L., Katzy R.E., Lelieveld L.T., Wu L., Roig-Zamboni V., Marel G.A. van der, Codee J.D.C., Sulzenbacher G., Davies G.J., Overkleeft H.S., Aerts J.M.F.G. & Artola Perez de Azanza M.E. (2022), 1,6-epi-Cyclophellitol cyclosulfamidate is a bona fide lysosomal α-glucosidase stabilizer for the treatment of Pompe disease, Journal of the American Chemical Society 144(32): 14819-14827.
- Zhang Y., Wang L., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2022), Assembly of a library of pel-oligosaccharides featuring α-glucosamine and α-galactosamine linkages, Frontiers in Chemistry 10: 842238.
- Tondini E., Reintjens N.R.M., Castello G., Arakelian T., Isendoorn M.M.E., Camps M., Vree J., Marel G.A. van der, Filippov D.V., Codee J.D.C. & Ossendorp F. (2022), Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control, npj Vaccines 7: 64.
- Minnee H., Rack J.G.M., Marel G.A. van der, Overkleeft H.S., Codee J.D.C., Ahel I. & Filippov D.V. (2022), Mimetics of ADP-ribosylated histidine through copper(I)-catalyzed click chemistry, Organic Letters 24(21): 3776-3780.
- Remmerswaal W.A., Houthuijs K.J., Ven R. van de, Elferink H., Hansen T., Berden G., Overkleeft H.S., Marel G.A. van der, Rutjes F., Filippov D.V., Boltje T.J., Martens J., Oomens J. & Codee J.D.C. (2022), Stabilization of glucosyl dioxolenium Ions by "dual participation" of the 2,2-dimethyl-2-(ortho-nitrophenyl)acetyl (DMNPA) protection group for 1,2-cis-glucosylation, Journal of Organic Chemistry (JOC) 87(14): 9139-9147.
- Peterse E., Meeuwenoord N.J., Elst H. van den, Marel G.A. van der, Overkleeft H.S. & Filippov D.V. (2022), Solid-phase synthesis of macrocyclic peptides via side-chain anchoring of the ornithine delta-amine, European Journal of Organic Chemistry 2022(11): e202101341.
- Demkiw K.M., Remmerswaal W.A., Hansen T., Marel G.A. van der, Codee J.D.C. & Woerpel K.A. (2022), Halogen atom participation in guiding the stereochemical outcomes of acetal substitution reactions, Angewandte Chemie 134(42): e202209401.
- Voorneveld J., Kloet M.S., Wijngaarden S., Kim R.Q., Moutsiopoulou A., Verdegaal M., Misra M., Dikic I., Marel G.A. van der, Overkleeft H.S., Filippov D.V. & Noort G.J.V. van (2022), Arginine ADP-ribosylation: chemical synthesis of post-translationally modified ubiquitin proteins, Journal of the American Chemical Society 144(45): 20582-20589.
- Speetjens F.M., Welters M.J.P., Slingerland M., Poelgeest M.I.E. van, Steenwijk P.J.D. van, Roozen I., Boekestijn S., Loof N.M., Zom G.G., Valentijn A.R.P.M., Krebber W.J., Meeuwenoord N.J., Janssen C.A.H., Melief C.J.M., Marel G.A. van der, Filippov D.V., Burg S.H. van der, Gelderblom H. & Ossendorp F. (2022), Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions, Journal for ImmunoTherapy of Cancer 10(10): e005016.
- Wang Z., Enotarpi J., Buffi G., Pezzicoli A., Gstöttner C.J., Nicolardi S., Balducci E., Fabbrini M., Romano M.R., Marel G.A. van der, Del Bino L., Adamo R. & Codée J.D.C. (2022), Chemical Synthesis and Immunological Evaluation of Fragments of the Multiantennary Group-Specific Polysaccharide of Group B Streptococcus, JACS Au 2(7): 1724-1735.
- Ende T.C. van den, Heuts J.M.M., Gential G.P.P., Visser M., Graaff M.J. van de, Ho N.I., Jiskoot W., Valentijn A.R.P.M., Meeuwenoord N.J., Overkleeft H.S., Codée J.D.C., Burg S.H. van der, Verdegaal E.M.E., Marel G.A. van der, Ossendorp F. & Filippov D.V. (2021), Simplified monopalmitoyl toll-like receptor 2 ligand mini-UPam for self-adjuvanting neoantigen-based synthetic cancer vaccines, ChemBioChem 22(7): 1215-1222.
- Dijk J.H.M. van, Hooij A. van, Groot L.M., Geboers J., Moretti R., Verhard-Seymonsbergen E., Jong D. de, Marel G.A. van der, Corstjens P.L.A.M., Codée J.D.C. & Geluk A. (2021), Synthetic Phenolic Glycolipids for application in diagnostic tests for leprosy, ChemBioChem 22(8): 1487-1493.
- Doelman W., Marqvorsen M.H.S., Chiodo F., Bruijns S.C.M., Marel G.A. van der, Kooyk Y. van, Kasteren S.I. van & Araman C. (2021), Synthesis of asparagine derivatives harboring a Lewis X type DC-SIGN ligand and evaluation of their impact on immunomodulation in multiple sclerosis, Chemistry: a European Journal 27(8): 2742-2752.
- Chen Y., Armstrong Z., Artola M., Florea B.I., Kuo C.L., Boer C. de, Rasmussen M.S., Abou Hachem M., Marel G.A. van der, Codee J.D.C., Aerts J.M.F.G., Davies G.J. & Overkleeft H.S. (2021), Activity-based protein profiling of retaining alpha-amylases in complex biological samples, Journal of the American Chemical Society 143(5): 2423-2432.
- McGregor N.G.S., Coines J., Borlandelli V.B., Amaki S., Artola M., Nin-Hill A., Linzel D., Yamada C., Arakawa T., Ishiwata A., Ito Y., Marel G.A. van der, Codee J.D.C., Fushinobu S., Overkleeft H.S., Rovira C. & Davies G.J. (2021), Cysteine nucleophiles in glycosidase catalysis: application of a covalent β‐l‐arabinofuranosidase inhibitor, Angewandte Chemie (International Edition) 60(11): 5754-5758.
- Hansen T., Vermeeren P., Yoshisada R., Filippov D.V., Marel G.A. van der, Codee J.D.C. & Hamlin T.A. (2021), How Lewis acids catalyze ring-openings of cyclohexene oxide, Journal of Organic Chemistry (JOC) 86(4): 3565-3573.
- Hendriks A., Dalen R. van, Ali S., Gerlach D., Marel G.A. van der, Fuchsberger F.F., Aerts P.C., Haas C.J.C. de, Peschel A., Rademacher C., Strijp J.A.G., Codée J.D.C. & Sorge N.M. van (2021), Impact of glycan linkage to staphylococcus aureus wall teichoic acid on langerin recognition and langerhans cell activation, ACS infectious diseases 7(3): 624-635.
- Wander D.P.A., Zanden S.Y. van der, Vriends M.B.L. Veen B.C. van, Vlaming J.G.C., Bruyning T., Hansen T., Marel G.A. van der, Overkleeft H.S., Neefjes J.J.C. & Codée J.D.C. (2021), Synthetic (N,N-dimethyl)doxorubicin glycosyl diastereomers to dissect modes of action of anthracycline anticancer drugs, Journal of Organic Chemistry (JOC) 86(8): 5757-5770.
- Ali S., Hendriks A., Dalen R. van, Bruyning T., Meeuwenoord N., Overkleeft H.S., Filippov D.V., Marel G.A. van der Sorge N.M. van & Codee J.D.C. (2021), (Automated) synthesis of well-defined staphylococcus aureus wall teichoic acid fragments, Chemistry: a European Journal 27(40): 10461-10469.
- Berni F., Wang L., Kalfopoulou E., Nguyen D.L., Es D. van der, Hübner J., Overkleeft H.S., Hokke C.H., Marel G.A. van der, Diepen A. van & Codée J.D.C. (2021), Generation of glucosylated sn-1-glycerolphosphate teichoic acids: glycerol stereochemistry affects synthesis and antibody interaction, RSC Chemical Biology 2(1): 187-191.
- Voorneveld J., Rack J.G.M., Gijlswijk L.M. van, Meeuwenoord N.J., Liu Q., Overkleeft H.S., Marel G.A. van der, Ahel I. & Filippov D.V. (2021), Molecular tools for the study of ADP-Ribosylation: a unified and versatile method to synthesise native mono-ADP-ribosylated peptides, Chemistry: a European Journal 27(41): 10621-10627.
- Schroder S.P., Offen W.A., Males A., Jin Y., Boer C. de, Enotarpi J., Marino L., Marel G.A. van der, Florea B.I., Codee J.D.C., Overkleeft H.S. & Davies G.J. (2021), Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases, Chemistry: a European Journal 27(37): 9519-9523.
- Liu Q., Knobloch G., Voorneveld J., Meeuwenoord N.J., Overkleeft H.S., Marel G.A. van der, Ladurner A.G. & Filippov D.V. (2021), Chemical synthesis of linear ADP-ribose oligomers up to pentamer and their binding to the oncogenic helicase ALC1, Chemical Science 12(37): 12468-12475.
- Berni F., Kalfopoulou E., Gimeno Cardells A.M., Carboni F., Es D. van der, Romero-Saavedra F., Laverde D., Miklic K., Malic S., Rovis T.L., Jonjic S., Ali S., Overkleeft H.S., Hokke C.H., Diepen A. van, Adamo R., Jiménez-Barbero J., Marel G.A. van der, Huebner J. & Codée J.D.C. (2021), Epitope recognition of a monoclonal antibody raised against a synthetic glycerol phosphate based teichoic acid, ACS Chemical Biology 16(8): 1344-1349.
- Reijneveld J.F., Marino L., Cao T.P., Cheng T.Y., Dam D., Shahine A., Witte M.D., Filippov D.V., Suliman S., Marel G.A. van der, Moody D.B., Minnaard A.J., Rossjohn J., Codee J.D.C. & Rhijn I. van (2021), Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells, Journal of Biological Chemistry 297(4): 101197.
- Harvey M.R., Chiodo F., Noest W., Hokke C.H., Marel G.A. & Codee J.D.C. (2021), Synthesis and antibody binding studies of schistosome-derived oligo-alpha-(1-2)-l-fucosides, Molecules 26(8): 2246.
- Rack J.G.M., Liu Q., Zorzini V., Voorneveld J., Ariza A., Ebrahimi K.H., Reber J.M., Krassnig S.C., Ahel D., Marel G.A. van der, Mangerich A., McCullagh J.S.O., Filippov D.V. & Ahel I. (2021), Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal, Nature Communications 12: 4581.
- Dijk H.J.M. van, Marel G.A. van der & Codée J.D.C. (2021), Developments in the synthesis of mycobacterial phenolic glycolipids, Chemical Record 21(11): 3295-3312.
- Ofman T.P., Küllmer F., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2021), An orthogonally protected cyclitol for the construction of nigerose- and dextran-mimetic cyclophellitols, Organic Letters 23(24): 9516-9519.
- Boer C. de, McGregor N.G.S., Peterse E., Schröder S.P., Florea B.I., Jiang J., Reijngoud J., Ram A.F.J., Wezel G.P. van, Marel G.A. van der, Codee J.D.C., Overkleeft H.S. & Davies G.J. (2021), Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases, RSC Chemical Biology 2(6): 1701.
- Li S., Wang Z., Marel G.A. van der & Codee J.D.C. (2021), Synthesis of uronic acid containing oligosaccharides. In: Barchi J.J. Jr. (red.), Comprehensive glycoscience . Comprehensive Glycoscience nr. 2: Elsevier. 200-227.
- Overkleeft H.S., Xin B.T., Espinal C.G.A., Bruin G. de, Filippov D.V., Marel G.A. van der & Florea B.I. (2020), Two-step bioorthogonal activity-based protein profiling of individual human proteasome catalytic sites, ChemBioChem 21(1-2): 248-255.
- Hogervorst T.P., Li R.J.E., Marino L., Bruijns S.C.M., Meeuwenoord N.J., Filippov D.V., Overkleeft H.S., Marel G.A. van der, Vliet S.J. van, Kooyk Y. van & Codée J.D.C. (2020), C-Mannosyl Lysine for Solid Phase Assembly of Mannosylated Peptide Conjugate Cancer Vaccines, ACS Chemical Biology 15(3): 728-739.
- McGregor N.G.S., Artola M., Nin-Hill A., Linzel D., Haon M., Reijngoud J., Ram A., Rosso M.N., Marel G.A. van der, Codée J.D.C., Wezel G.P. van, Berrin J.G., Rovira C., Overkleeft H.S. & Davies G.J. (2020), Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases, Journal of the American Chemical Society 142(10): 4648-4662.
- Laverde D., Romero-Saavedra F., Argunov D.A., Enotarpi J., Krylov V.B., Kalfopoulou E., Martini C., Torelli R., Marel G.A. van der, Sanguinetti M., Codée J.D.C., Nifantiev N.E. & Huebner J. (2020), Synthetic oligomers mimicking capsular polysaccharide diheteroglycan are potential vaccine candidates against encapsulated Enterococcal infections, ACS infectious diseases 6(7): 1816-1826.
- Wang L., Zhang Y., Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2020), Reagent controlled glycosylations for the assembly of well-defined Pel oligosaccharides, Journal of Organic Chemistry (JOC) 85(24): 15872-15884.
- Anoniem (2020), Reagent controlled stereoselective synthesis of teichoic acid α-(1,2)-glucans [Glycovax] (vertaling Wang L., Berni F., Enotarpi J., Overkleeft H.S., Marel G.A. van der & Codée J.D.C.), Organic and Biomolecular Chemistry 18(11): 2038-2050.
- Codée J.D.C., Zhang Y., Gómez-Redondo M., Jiménez-Osés G., Arda A., Overkleeft H.S., Marel G.A. van der & Jiménez-Barbero J. (2020), Synthesis and structural analysis of Aspergillus fumigatus galactosaminogalactans featuring α-galactose, α-galactosamine and α-N-acetyl galactosamine linkages, Angewandte Chemie (International Edition) 59(31): 12746-12750.
- Mechelen J. van, Voorneveld J., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Synthesis of orthogonally protected and functionalized bacillosamines, Organic and Biomolecular Chemistry 18(15): 2834-2837.
- Hansen T. Elferink H. Hengst J.M.A. van Houthuijs K.J. Remmerswaal W.A. Kromm A. Berden G. Vorm S. van der Rijs A.M. Overkleeft H.S. Filippov D.V. Rutjes F.P.J.T. Marel G.A. van der Martens J. Oomens J. Codée J.D.C. Boltje T.J. (2020), Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions, Nature Communications 11(1): 2664.
- Armstrong Z., Kuo C.L., Lahav D., Liu B., Johnson R., Beenakker T.J.M., Boer C. de, Wong C.S., Rijssel E.R. van, Debets M.F., Florea B.I., Hissink C., Boot R.G., Geurink P.P., Ovaa H., Stelt M. van der, Marel G.A. van der, Codée J.D.C., Aerts J.M.F.G., Wu L., Overkleeft H.S. & Davies G.J. (2020), Manno-epi-cyclophellitols enable activity-based protein profiling of human α-mannosidases and discovery of new golgi mannosidase II inhibitors, Journal of the American Chemical Society 142(30): 13021-13029.
- Enotarpi J.Tontini M. Balocchi C. Es D. van der Auberger L. Balducci E. Carboni F. Proietti D. Casini D. Filippov D.V. Overkleeft H.S. Marel G.A. van der Colombo C. Romano M.R. Berti F. Costantino P. Codeé J.D.C. Lay L. Adamo R. (2020), A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A, Nature Communications 11: 4434.
- Reintjens N.R.M., Tondini E., Vis C., McGlinn T., Meeuwenoord N.J., Hogervorst T.P., Overkleeft H.S., Filippov D.V., Marel G.A. van der, Ossendorp F.A. & Codée J.D.C. (2020), Multivalent, stabilized mannose-6-phosphates for the targeted delivery of toll-like receptor ligands and peptide antigens, ChemBioChem 22(2): 434-440.
- Hansen T., Ofman T.P., Vlaming J.G.C., Gagarinov I.A., Beek J. van, Goté T.A., Tichem J.M., Ruijgrok G., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Reactivity-stereoselectivity mapping for the assembly of Mycobacterium marinum lipooligosaccharides, Angewandte Chemie (International Edition) 60(2): 937-945.
- Reintjens N.R.M., Koemans T.S., Zilverschoon N., Castelli R., Cordfunke R.A., Drijfhout J.W., Meeuwenoord N.J., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Synthesis of C-Glycosyl Amino Acid Building Blocks Suitable for the Solid-Phase Synthesis of Multivalent Glycopeptide Mimics, European Journal of Organic Chemistry 2020(32): 5126-5139.
- Li R.J.E., Hogervorst T.P., Achilli S., Bruijns S.C.M., Spiekstra S., Vives C., Thepaut M., Filippov D.V., Marel G.A. van der, Vliet S.J. van, Fieschi F., Codee J.D.C. & Kooyk Y. van (2020), Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens, Frontiers in Cell and Developmental Biology 8: 556.
- Wander D.P.A., Zanden S.Y. van der, Marel G.A. van der, Overkleeft H.S., Neefjes J.J.C. & Codee J.D.C. (2020), Doxorubicin and aclarubicin: shuffling anthracycline glycans for improved anticancer agents, Journal of Medicinal Chemistry 63(21): 12814-12829.
- Enotarpi J., Tontini M., Balocchi C., Es D. van der, Auberger L.C., Balducci E., Carboni F., Proietti D., Casini D., Filippov D.V., Overkleeft H.S., Marel G.A. van der, Colombo C., Romano M.R., Berti F., Costantino P., Codeé J.D.C., Lay L. & Adamo R. (2020), Publisher correction: a stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A, Nature Communications 11(1): 6155.
- Reintjens N.R.M., Tondini E., Jong A.R. de, Meeuwenoord N.J., Chiodo F., Peterse E., Overkleeft H.S., Filippov D.V., Marel G.A. van der, Ossendorp F.A. & Codée J.D.C. (2020), Self-adjuvanting cancer vaccines from conjugation-ready lipid A analogues and synthetic long peptides, Journal of Medicinal Chemistry 63(20): 11691-11706.
- Boer C. de, McGregor N.G.S., Peterse E., Schröder S.P., Florea B.I., Jiang J., Reijngoud J., Ram A.F.J., Wezel G.P. van, Marel G.A. van der, Codée J.D.C., Overkleeft H.S. & Davies G.J. (2020), Glycosylated cyclophellitol-derived activity-based probes and inhibitors for cellulases, RSC Chemical Biology 1(3): 148-155.
- Berni F., Enotarpi J., Voskuilen T., Li S., Marel G.A. van der & Codée J.D.C. (2020), Synthetic carbohydrate-based cell wall components from Staphylococcus aureus, Drug Discovery Today: Technologies 38: 35-43.
- Artola M., Kuo C.L., Lelieveld L.T., Rowland R.J., Marel G.A. van der, Codée J.D.C., Boot R.G., Davies G.J., Aerts J.M.F.G. & Overkleeft H.S. (2019), Functionalized cyclophellitols are selective glucocerebrosidase inhibitors and induce a bona fide neuropathic Gaucher model in zebrafish, Journal of the American Chemical Society 141(10): 4214-4218.
- Madern J.M., Hansen T., Rijssel E.R. van, Kistemaker H.A.V., Vorm S. van der, Overkleeft H.S., Marel G.A. van der, Filippov D.V. & Codee J.D.C. (2019), Synthesis, Reactivity, and Stereoselectivity of 4-Thiofuranosides, Journal of Organic Chemistry (JOC) 84(3): 1218-1227.
- Zom G.G., Willems M.M.J.H.P., Meeuwenoord N., Reintjens N.R.M., Tondini E., Khan S., Overkleeft H.S., Marel G.A. van der, Codée J.D.C., Ossendorp F. & Filippov D.V. (2019), Dual Synthetic Peptide Conjugate Vaccine Simultaneously Triggers TLR2 and NOD2 and Activates Human Dendritic Cells, Bioconjugate Chemistry 30(4): 1150-1161.
- Vorm S. van der, Hansen T., Rijssel E.R. van, Dekkers R., Madern J.M., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2019), Furanosyl oxocarbenium ion Conformational Energy Landscape maps as a tool to study the glycosylation stereoselectivity of 2-azidofuranoses, 2-fluorofuranoses and methyl furanosyl uronates, Chemistry: a European Journal 25(29): 7149-7157.
- Gential G.P.P., Hogervorst T.P., Tondini E., Graaff M.J. van de, Overkleeft H.S., Codée J.D.C., Marel G.A. van der, Ossendorp F. & Filippov D.V. (2019), Peptides conjugated to 2-alkoxy-8-oxo-adenine as potential synthetic vaccines triggering TLR7, Bioorganic and Medicinal Chemistry Letters 29(11): 1340-1344.
- Wang L., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2019), Reagent Controlled Stereoselective Assembly of alpha-(1,3)-Glucans, European Journal of Organic Chemistry 2019(10): 1994-2003.
- Hansen T., Lebedel L., Remmerswaal W.A., Vorm S. van der, Wander D.P.A., Somers M., Overkleeft H.S., Filippov D.V., Désiré J., Mingot A., Bleriot Y., Marel G.A. van der, Thibaudeau S. & Codée J.D.C. (2019), Defining the SN1 Side of Glycosylation Reactions: Stereoselectivity of Glycopyranosyl Cations, ACS Central Science 5(5): 781-788.
- Schröder S.P., Boer C. de, McGregor N.G.S., Rowland R.J., Moroz O., Blagova E., Reijngoud J., Arentshorst M., Osborn D., Morant M.D., Abbate E., Stringer M.A., Krogh K.B.R.M., Raich L., Rovira C., Wezel G.P. van, Berrin J.G., Florea B.I., Ram A.F.J., Codée J.D.C., Marel G.A. van der, Wu L., Wilson K.S., Overkleeft H.S. & Davies G.J. (2019), Dynamic and functional profiling of Xylan-degrading enzymes in aspergillus secretomes using activity-based probes, ACS Central Science 5(6): 1067-1078.
- Vorm S. van der, Hansen T., Hengst J.M.A. van, Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2019), Acceptor reactivity in glycosylation reactions, Chemical Society Reviews 48(17): 4688-4706.
- Zhang Q., Gimeno A., Santana D., Wang Z., Valdés-Balbin Y., Rodríguez-Noda L.M., Hansen T., Kong L., Shen M., Overkleeft H.S., Vérez-Bencomo V., Marel G.A. van der, Jiménez-Barbero J., Chiodo F. & Codée J.D.C. (2019), Synthetic, Zwitterionic Sp1 Oligosaccharides Adopt a Helical Structure Crucial for Antibody Interaction, ACS Central Science 5(8): 1407-1416.
- Hendrikse S.I.S., Su L., Hogervorst T.P., Lafleur R.P.M., Lou X., Marel G.A. van der, Codee J.D.C. & Meijer E.W. (2019), Elucidating the Ordering in Self-Assembled Glycocalyx Mimicking Supramolecular Copolymers in Water, Journal of the American Chemical Society 141(35): 13877-13886.
- Liu Q., Marel G.A. van der & Filippov D.V. (2019), Chemical ADP-ribosylation: mono-ADPr-peptides and oligo-ADP-ribose, Organic and Biomolecular Chemistry 17(22): 5460-5474.
- Li R.E., Hogervorst T.P., Achilli S., Bruijns S.C., Arnoldus T., Vivès C., Wong C.C., Thépaut M., Meeuwenoord N.J., Elst H Van den, Overkleeft H.S., Marel G.A. van der, Filippov D.V., Vliet S.J. van, Fieschi F., Codee J.D.C. & Kooyk Y. van (2019), Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen, Frontiers in Chemistry 7: 650.
- Artola M., Hedberg C., Rowland R.J., Raich L., Kytidou K., Wu L., Schaaf A., Ferraz M.J., Marel G.A. van der, Codee J.D.C., Rovira C., Aerts J.M.F.G., Davies G.J. & Overkleeft H.S. (2019), Alpha-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal alpha-galactosidase A in Fabry disease, Chemical Science 10(40): 9233-9243.
- Liu B., Mechelen J. van, Berg R.J.B.H.N. van den, Nieuwendijk A.M.C.H. van den, Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2019), Synthesis of glycosylated 1-deoxynojirimycins starting from natural and synthetic disaccharides, European Journal of Organic Chemistry 2019(1): 118-129.
- Artola Perez de Azanza M.E., Wouters S., Schröder S.P., Boer C. de, Chen Y., Petracca R., Nieuwendijk A.M.C.H. van den, Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2019), Direct Stereoselective Aziridination of Cyclohexenols with 3-Amino-2-(trifluoromethyl)quinazolin-4(3H)-one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors, European Journal of Organic Chemistry 2019(6): 1397-1404.
- Xin B.T., Huber E.M., Bruin G. de, Heinemeyer W., Maurits E., Espinal C., Du Y., Janssens M., Weyburne E.S., Kisselev A.F., Florea B.I., Driessen C., Marel G.A., Groll M. & Overkleeft H.S. (2019), Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits, Journal of Medicinal Chemistry 62(3): 1626-1642.
- Volbeda A.G., Marel G.A. van der & Codée J.D.C. (2018), Protecting Group Strategies in Carbohydrate Chemistry. In: Vidal S. (red.), Protecting Groups in Carbohydrate Chemistry and Applications: Wiley. 1-27.
- Liu Q., Kistemaker H.A.V., Bhogaraju S., Dikic I., Overkleeft H.S., Marel G.A. van der, Ovaa H., Heden van Noort G.J. van der & Filippov D.V. (2018), A General Approach Towards Triazole-Linked Adenosine Diphosphate Ribosylated Peptides and Proteins, Angewandte Chemie (International Edition) 57(6): 1659-1662.
- Mangsbo S.M., Fletcher E.A.K., Maren W.W.C. van, Redeker A., Cordfunke R.A., Dillmann I., Dinkelaar J., Ouchaou K., Codee J.D.C., Marel G.A. van der, Hoogerhout P., Melief C.J.M., Ossendorp F. & Drijfhout J.W. (2018), Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses, Molecular Immunology 93: 115-124.
- Schröder S.P., Wu L., Artola Perez de Azanza M.E., Hansen T., Offen W.A., Guimaraes da Lomba Ferraz M.J., Li K.-Y., Aerts J.M.F.G., Marel G.A. van der, Codee J.D.C., Davies G.J. & Overkleeft H.S. (2018), Gluco-1H-imidazole: A New Class of Azole-Type beta-Glucosidase Inhibitor, Journal of the American Chemical Society 140(15): 5045-5048.
- Schröder S.P., Kallemeijn W.W., Debets M.F., Hansen T., Sobala L.F., Hakki Z., Williams S.J., Beenakker T.J.M., Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C., Davies G.J. & Overkleeft H.S. (2018), Spiro-epoxyglycosides as activity-based probes for glycoside hydrolase family 99 endomannosidase/endomannanase, Chemistry: a European Journal 24(39): 9983-9992.
- Wang L., Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2018), Reagent Controlled Stereoselective assembly of alpha-(1-3)-Glucans, Journal of the American Chemical Society 140(13): 4632–4638.
- Vorm S. van der, Hengst J.M.A. van, Bakker M.H.E., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2018), Mapping the Relationship between Glycosyl Acceptor Reactivity and Glycosylation Stereoselectivity, Angewandte Chemie (International Edition) 57(27): 8240-8244.
- Engelsma S.B., Ende T.C. van den, Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2018), Reaction Rates of Various N-Acylenamines in the Inverse-Electron-Demand Diels-Alder Reaction, European Journal of Organic Chemistry (20-21): 2587-2591.
- Es D. van der, Berni F., Hogendorf W.F.J., Meeuwenoord N., Laverde D., Diepen A. van, Overkleeft H.S., Filippov D.V., Hokke C.H., Huebner J., Marel G.A. van der & Codée J.D.C. (2018), Streamlined Synthesis and Evaluation of Teichoic Acid Fragments, Chemistry: a European Journal 24(16): 4014-4018.
- Beenakker T.J.M., Wander D.P.A., Codée J.D.C., Aerts J.M.F.G., Marel G.A. van der & Overkleeft H.S. (2018), Synthesis of Carba-Cyclophellitols: a New Class of Carbohydrate Mimetics, European Journal of Organic Chemistry 2018(20-21): 2504-2517.
- Voorneveld J., Rack J.G.M., Ahel I., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2018), Synthetic alpha- and beta-Ser-ADP-ribosylated Peptides Reveal alpha-Ser-ADPr as the Native Epimer, Organic Letters 20(13): 4140-4143.
- Artola M., Kuo C.L., McMahon S.A., Oehler V., Hansen T., Lienden M.J.C. van der, He X., Elst H. van den, Florea B.I., Kermode A.R., Marel G.A. van der, Gloster T.M., Codée J.D.C., Overkleeft H.S. & Aerts J.M.F.G. (2018), New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes, Chemistry: a European Journal 24(71): 19081-19088.
- Fletcher E.A.K., Maren W. van, Cordfunke R., Dinkelaar J., Codee J.D.C., Marel G.A. van der, Melief C.J.M., Ossendorp F., Drijfhout J.W. & Mangsbo S.M. (2018), Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System, Journal of Immunology 201(1): 87-97.
- Zom G.G., Willems M.M.J.H.P., Khan S., Sluis T.C. van der, Kleinovink J.W., Camps M.G.M., Marel G.A. van der, Filippov D.V., Melief C.J.M. & Ossendorp F.A. (2018), Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication, Journal for ImmunoTherapy of Cancer 6(1): 146.
- Hagen B., Vorm S. van der, Hansen T., Marel G.A. van der & Codée J.D.C. (2017), Stereoselective glycosylations - Additions to oxocarbenium ions. In: Bennett C. (red.), Selective Glycosylations – Synthetic Methods and Catalysts: Wiley.
- Es D. van der, Hogendorf W.F.J., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), Teichoic Acids: Synthesis and Applications, Chemical Society Reviews 46: 1464-1482.
- Hagen B., Ali S., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), Mapping the reactivity and selectivity of 2-azidofucosyl donors for the efficient assembly of N-acetyl fucosamine containing bacterial oligosaccharides, Journal of Organic Chemistry (JOC) 82(2): 848–868.
- Vorm S. van der, Hansen T., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), The Influence of Acceptor Nucleophilicity on the Glycosylation Reaction Mechanism, Chemical Science 2017(8): 1867-1875.
- Mirzaian M., Wisse P., Guimaraes da Lomba Ferraz M.J., Marques A.R.A., Gaspar P., Oussoren S.V., Kytidou K., Codée J.D.C., Marel G.A. van der, Overkleeft H.S. & Aerts J.M.F.G. (2017), Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical C-13-encoded internal standards, Clinica Chimica Acta 466: 178-184.
- Rijssel E.R. van, Janssen A.P.A., Males A., Davies G.J., Marel G.A. van der, Overkleeft H.S. & Codee J.D.C. (2017), Conformational behaviour of Azasugars based on mannuronic acid, ChemBioChem 18(13): 1297-1304.
- Lahav D., Liu B., Berg R.J.B.H.N. van den, Nieuwendijk A.M.C.H. van den, Wennekes T., Ghisaidoobe A.T., Breen I., Ferraz M.J., Kuo C.L., Wu L., Geurink P.P., Ovaa H., Marel G.A. van der, Stelt M. van der, Boot R.G., Davies G.J., Aerts J.M.F.G. & Overkleeft H.S. (2017), A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase, Journal of the American Chemical Society 138(40): 14192-14197.
- Narhe B.D., Breman A.C., Padwal J., Vandenput D.A.L., Scheidt J.M., Benningshof J.C.J., Marel G.A. van der, Overkleeft H.S., Stelt M. van der & Filippov D.V. (2017), Piperidine and octahydropyrano[3,4-c] pyridine scaffolds for drug-like molecular libraries of the European Lead Factory, Bioorganic & Medicinal Chemistry 25(19): 5160-5170.
- Artola Perez de Azanza M.E., Wu L., Guimaraes da Lomba Ferraz M.J., Kuo C.L., Raich L., Breen I.Z., Offen W.A., Codee J.D.C., Marel G.A. van der, Rovira C., Aerts J.M.F.G., Davies G.J. & Overkleeft H.S. (2017), 1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor, ACS Central Science 3(7): 784-793.
- Wu L., Jiang J., Jin Y., Kallemeijn W.W., Kuo C.-L., Artola M., Dai W., Elk C. van, Eijk M. van, Marel G.A. van der, Codee J.D.C., Florea B.I., Aerts J.M.F.G., Overkleeft H.S. & Davies G.J. (2017), Activity-based probes for functional interrogation of retaining beta-glucuronidases, Nature Chemical Biology 13(8): 867-873.
- Beenakker T.J.M., Wander D.P.A., Offen W.A., Artola Perez de Azanza M.E., Raich L., Guimaraes da Lomba Ferraz M.J., Li K.Y., Houben J.H.P.M., Rijssel E.R. van, Hansen T., Marel G.A. van der, Codee J.D.C., Aerts J.M.F.G., Rovira C., Davies G.J. & Overkleeft H.S. (2017), Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors, Journal of the American Chemical Society 139(19): 6534-6537.
- Jiang J., Kuo C.L., Wu L., Franke C., Kallemeijn W.W., Florea B.I., Meel H.M.M. van, Marel G.A. van der, Codee J.D.C., Boot R.G., Davies G.J., Overkleeft H.S. & Aerts J.M.F.G. (2017), Correction to "Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes", ACS Central Science 3(6): 673.
- Schröder S.P., Sande J.W. van de, Kallemeijn W.W., Kuo C.L., Artola Perez de Azanza M.E., Rooden E.J. van, Jiang J., Beenakker T.J.M., Florea B.I., Offen W.A., Davies G.J., Minnaard A.J., Aerts J.M.F.G., Codee J.D.C., Marel G.A. van der & Overkleeft H.S. (2017), Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines, Chemical Communications 53(93): 12528-12531.
- Zhang Q., Howell P.L., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codee J.D.C. (2017), Chemical synthesis of guanosine diphosphate mannuronic acid (GDPManA) and its C-4-O-methyl and C-4-deoxy congeners, Carbohydrate Research 450: 12-18.
- Volbeda A.G., Mechelen J. van, Meeuwenoord N., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), Cyanopivaloyl Ester in the Automated Solid-Phase Synthesis of Oligorhamnans, Journal of Organic Chemistry (JOC) 82(24): 12992-13002.
- Liu Q., Kistemaker H.A.V., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2017), Synthesis of ribosyl-ribosyl-adenosine-5 ',5 '',5'''(triphosphate)-the naturally occurring branched fragment of poly(ADP ribose), Chemical Communications 53(74): 10255-10258.
- Hagen B., Dijk J.H.M. van, Zhang Q., Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), Synthesis of the Staphylococcus aureus Strain M Capsular Polysaccharide Repeating Unit, Organic Letters 19(10): 2514-2517.
- Zhang Qingju, Overkleeft Herman S., Van der Marel Gijsbert A. & Codee Jeroen D.C. (2017), Synthetic zwitterionic polysaccharides, Current Opinion in Chemical Biology 40: 95-101.
- Engelsma S.B., Meeuwenoord N.J., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2017), Combined Phosphoramidite-Phosphodiester Reagents for the Synthesis of Methylene Bisphosphonates, Angewandte Chemie (International Edition) 56(11): 2955-2959.
- Vorm S. van der, Overkleeft H.S., Marel G.A. van der & Codee J.D.C. (2017), Stereoselectivity of Conformationally Restricted Glucosazide Donors, Journal of Organic Chemistry (JOC) 82(9): 4793-4811.
- Stolze S.C., Liu N., Wijdeven R.H., Tuin A.W., Nieuwendijk A.M. van den, Florea B.I., Stelt M. van der, Marel G.A. van der, Neefjes J.J. & Overkleeft H.S. (2016), Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes, Molecular Biosystems 12(6): 1809-1817.
- Xin B.T., Bruin G. de, Huber E.M., Besse A., Florea B.I., Filippov D.V., Marel G.A. van der, Kisselev A.F., Stelt M. van der, Driessen C., Groll M. & Overkleeft H.S. (2016), Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes, Journal of Medicinal Chemistry 59(15): 7177-7187.
- Willems M.M.J.H.P., Zom G.G., Meeuwenoord N.J., Khan S., Ossendorp F.A., Overkleeft H.S., Marel G.A. van der, Filippov D.V. & Codée J.D.C. (2016), Lipophilic muramyl dipeptide-antigen conjugates as immunostimulating agents, ChemMedChem 11(2): 190-198.
- Bruin G. de, Xin B.T., Kraus M., Stelt M. van der, Marel G.A. van der, Kisselev A.F., Driessen C., Florea B.I. & Overkleeft H.S. (2016), A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities, Angewandte Chemie (International Edition) 55(13): 4199-4203.
- Xin B.T., Bruin G. de, Plomp J.W., Florea B.I., Marel G.A. van der & Overkleeft H.S. (2016), Incorporation of the Constrained Peptidomimetic, 5-Methylpyridin-2-one into Peptide Vinyl Sulfones and Peptide Epoxy Ketones is Detrimental for Proteasome Inhibition, European Journal of Organic Chemistry (6): 1132-1144.
- Bruin G. de, Mock E.D., Hoogendoorn S., Nieuwendijk A.M.C.H. van den, Mazurek J., Marel G.A. van der, Florea B.I. & Overkleeft H.S. (2016), Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib, Chemical Communications 52(21): 4064-4067.
- Xin B.T., Schimmack G., Du Y., Florea B.I., Marel G.A. van der, Driessen C., Krappmann D. & Overkleeft H.S. (2016), Development of new Malt1 inhibitors and probes, Bioorganic & Medicinal Chemistry 24(15): 3312-3329.
- Mirzaian M., Wisse P., Ferraz M.J., Marques A.R., Gabriel T.L., Roomen C.P. van, Ottenhoff R., Eijk M. van, Codée J.D., Marel G.A. van der, Overkleeft H.S. & Aerts J.M. (2016), Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard, Clinica Chimica Acta 459: 36-44.
- Jiang J., Artola Perez de Azanza M.E., Beenakker T.J.M., Schröder S.P., Petracca R., Boer C. de, Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2016), The synthesis of cyclophellitol-aziridine and its configurational and functional isomers, European Journal of Organic Chemistry 2016(22): 3671-3678.
- Gential G.P., Ho N.I., Chiodo F., Meeuwenoord N., Ossendorp F., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2016), Synthesis and evaluation of fluorescent Pam3Cys peptide conjugates, Bioorganic and Medicinal Chemistry Letters 26(15): 3641-5.
- Es D. van der, Groenia N.A., Laverde D., Overkleeft H.S., Huebner J., Marel G.A. van der & Codee J.D.C. (2016), Synthesis of E. faecium wall teichoic acid fragments, Bioorganic & Medicinal Chemistry 24(17): 3893-3907.
- Zom G.G., Welters M.J., Loof N.M., Goedemans R., Lougheed S., Valentijn R.R., Zandvliet M.L., Meeuwenoord N.J., Melief C.J., Gruijl T.D. de, Marel G.A. van der, Filippov D.V., Ossendorp F. & Burg S.H. van der (2016), TLR2 ligand-synthetic long peptide conjugates effectively stimulate tumor-draining lymph node T cells of cervical cancer patients, OncoTarget : .
- Kistemaker H.A., Nardozza A.P., Overkleeft H.S., Marel G.A. van der, Ladurner A.G. & Filippov D.V. (2016), Synthesis and macrodomain binding of mono-ADP-ribosylated peptides, Angewandte Chemie (International Edition) 55(36): 10634-8.
- Zhang Q., Rijssel E.R. van, Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2016), On the Reactivity of Gulose and Guluronic Acid Building Blocks in the Context of Alginate Assembly, European Journal of Organic Chemistry 2016(14): 2393-2397.
- Schroder S., Petracca R., Minnee H., Artola M., Aerts J.M.F.G., Codée J.D.C., Marel G.A. van der & Overkleeft H.S. (2016), A Divergent Synthesis of L-arabino- and D-xylo-configured Cyclophellitol Epoxides and Aziridines, European Journal of Organic Chemistry : .
- Volbeda A.G., Reintjens N.R.M., Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2016), The Cyanopivaloyl Ester: A Protecting Group in the Assembly of Oligorhamnans, European Journal of Organic Chemistry 2016(31): 5282-5293.
- Jiang J., Kuo C.L., Wu L., Franke C., Kallemeijn W.W., Florea B.I., Meel H.M.M. van, Marel G.A. van der, Codée J.D.C., Boot R.G., Davies G.J., Overkleeft H.S. & Aerts J.M.F.G. (2016), Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes, ACS Central Science 2(5): 351-358.
- Zhang Q., Rijssel E.R. van, Walvoort M.T.C., Overkleeft H.S., Marel G.A. van der & Codée J.D.C. (2015), Acceptor reactivity in the total synthesis of alginate fragments containing α-L-guluronic acid and β-D-mannuronic acid, Angewandte Chemie (International Edition) 54(26): 7670-7673.
- Wisse P., Geus M.A.R. de, Cross G., Nieuwendijk A.M.C.H. van den, Rooden E.J. van, Berg R.J.B.H.N. van den, Aerts J.M.F.G., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2015), Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy, Journal of Organic Chemistry (JOC) 80(14): 7258-65.
- Ouairy C.M.J., Ferraz M.J., Boot R.G., Baggelaar M.P., Stelt M. van der, Appelman M., Marel G.A. van der, Florea B.I., Aerts J.M.F.G. & Overkleeft H.S. (2015), Development of an acid ceramidase activity-based probe, Chemical Communications 51(28): 6161-6163.
- Liu N., Hoogendoorn S., Kar B. van de, Kaptein A., Barf T., Driessen C., Filippov D.V., Marel G.A. van der, Stelt M. van der & Overkleeft H.S. (2015), Direct and two-step bioorthogonal probes for Bruton's tyrosine kinase based on ibrutinib: a comparative study, Organic and Biomolecular Chemistry 13(18): 5147-5157.
- Padwal J.D., Filippov D.V., Narhe B.D., Aertssen S., Beuving R.J., Benningshof J.C.J., Marel G.A. van der, Overkleeft H.S. & Van der Stelt M. (2015), Cyclopentitol as a scaffold for a natural product-like compound library for drug discovery, Bioorganic & Medicinal Chemistry 23(11): 2650-2655.
- Hoogendoorn S., Mock E.D., Strijland A., Donker-Koopman W.E., Elst H. van den, Berg R.J.B.H.N. van den, Aerts J.M.F.G., Marel G.A. van der & Overkleeft H.S. (2015), Ortho-Carborane-modified N-substituted Deoxynojirimycins, European Journal of Organic Chemistry 2015(20): 4437-4446.
- Jiang J., Beenakker T.J.M., Kallemeijn W.W., Marel G.A. van der, Elst H. van der, Codee J.D.C., Aerts J.M.F.G. & Overkleeft H.S. (2015), Comparing Cyclophellitol N-Alkyl and N-Acyl Cyclophellitol Aziridines as Activity-Based Glycosidase Probes, Chemistry: a European Journal 21(30): 10861-10869.
- Volbeda A.G., Kistemaker H.A.V., Overkleeft H.S., Marel G.A. van der, Filippov D.V. & Codee J.D.C. (2015), Chemoselective cleavage of p-methoxybenzyl and 2-naphthylmethyl ethers using a catalytic amount of HCl in hexafluoro-2-propanol, Journal of Organic Chemistry (JOC) 80(17): 8796-8806.
- Wong C.S., Hoogendoorn S., Marel G.A. van der, Overkleeft H.S. & Codee J.D.C. (2015), Targeted Delivery of Fluorescent High-Mannose-Type Oligosaccharide Cathepsin Inhibitor Conjugates, ChemPlusChem 80(6): 928-937.
- Ouchaou K., Maire F., Salo O., Ali H., Hankemeier T., Marel G.A. van der, Filippov D.V., Bovenberg R.A.L., Vreeken R.J., Driessen A.J.M. & Overkleeft H.S. (2015), A Mutasynthesis Approach with a Penicillium chrysogenum Delta roqA Strain Yields New Roquefortine D Analogues, ChemBioChem 16(6): 915-923.
- Kistemaker H.A.V., Lameijer L.N., Meeuwenoord N.J., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2015), Synthesis of Well-Defined Adenosine Diphosphate Ribose Oligomers, Angewandte Chemie (International Edition) 54(16): 4915-4918.
- Jiang J., Kallemeijn W.W., Wright D.W., Nieuwendijk A.M.C.H. van den, Coco Rohde V., Folch E.C., Elst H. van den, Florea B.I., Scheij S., Donker-Koopman W.E., Verhoek M., Li N., Schürmann M., Mink D., Boot R.G., Codée J.D.C., Marel G.A. van der, Davies G.J., Aerts J.M.F.G. & Overkleeft H.S. (2015), In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 alpha-L-fucosidases, Chemical Science 6(5): 2782-2789.
- Kistemaker H.A.V., Meeuwenoord N.J., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2015), On the synthesis of oligonucleotides interconnected through pyrophosphate linkages, European Journal of Organic Chemistry 2015(27): 6084-6091.
- Rijssel E.R. van, Delft P. van, Marle D.V. van, Bijvoets S.M., Lodder G., Overkleeft H.S., Marel G.A. van der, Filippov D.V. & Codee J.D.C. (2015), Stereoselectivity in the Lewis Acid Mediated Reduction of Ketofuranoses, Journal of Organic Chemistry (JOC) 80(9): 4553-4565.
- Kistemaker H.A.V., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2015), Branching of poly(ADP-ribose): Synthesis of the Core Motif, Organic Letters 17(17): 4328-4331.
- Berg R.J.B.H.N. van der, Rijssel E.R. van, Ferraz M.J., Houben J., Strijland A., Donker-Koopman W.E., Wennekes T., Bonger K.M., Ghisaidoobe A.B.T., Hoogendoorn S., Marel G.A. van der, Codee J.D.C., Overkleeft H.S. & Aerts J.M.F.G. (2015), Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors, ChemMedChem 10(12): 2042-2062.
- Wisse P., Gold H., Mirzaian M., Guimaraes Da Lomba Ferraz M.J., Lutteke G., Berg R.J.B.H.N. van den, Elst H. van den, Lugtenburg J., Marel G.A. van der, Aerts J.M.F.G., Codee J.D.C. & Overkleeft H.S. (2015), Synthesis of a panel of carbon-13-labelled (glyco)sphingolipids, European Journal of Organic Chemistry 2015(12): 2661-2677.
- Kallemeijn W.W., Witte M.D., Voorn-Brouwer T.M., Walvoort M.T.C., Li K.Y., Codee J.D.C., Marel G.A. van der, Boot R.G., Overkleeft H.S. & Aerts J.M.F.G. (2014), A Sensitive Gel-Based Method Combining Distinct Cyclophellitol-Based Probes for the Identification of Acid/Base Residues in Human Retaining Beta-Glucosidases, Journal of Biological Chemistry 289(51): 35351-35362.
- Duivenvoorden B.A., Ghauharali K., Scheij S., Boot R.G., Aerts J.M.F.G., Marel G.A. van der, Overkleeft H.S. & Codee J.D.C. (2014), Design and synthesis of 4 '-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates, Carbohydrate Research 399: 26-37.
- Li K.Y., Jiang J., Witte M.D., Kallemeijn W.W., Donker-Koopman W.E., Boot R.G., Aerts J.M.F.G., Codee J.D.C., Marel G.A. van der & Overkleeft H.S. (2014), Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors, 12(39): 7786-7791.
- Willems L.I., Beenakker T.J.M., Murray B., Scheij S., Kallemeijn W.W., Boot R.G., Verhoek M., Donker-Koopman W.E., Guimaraes da Lomba Ferraz M.J., Rijssel E.R. van, Florea B.I., Codee J.D.C., Marel G.A. van der, Aerts J.M.F.G. & Overkleeft H.S. (2014), Potent and Selective Activity-Based Probes for GH27 Human Retaining alpha-Galactosidases, Journal of the American Chemical Society 136(33): 11622-11625.
- Zom G.G., Filippov D.V., Marel G.A. van der, Overkleeft H.S., Melief C.J. & Ossendorp F.A. (2014), Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule, OncoImmunology 3(7): e947892.
- Jong A.R. de, Hagen B., Sheerin K., Codée J.D.C. & Marel G.A. van der (2014), Hydrolysis of Thioglycosides using Anhydrous NIS and TFA. In: Marel G.A. van der & Codee J.D.C. (red.), Carbohydrate Chemistry: Proven Synthetic Methods nr. 2: CRC Press. 71-76.
- Marel G.A. van der & Codee J. (2014), Carbohydrate Chemistry: Proven Synthetic Methods nr. 2: CRC Press.
- Delft P. van, Witte W.E.A. de, Meeuwenoord N.J., Noort G.J. van der Heden van, Versluis F., Olsthoorn R.R.C.L., Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2014), Design of a ribosyltriazole-annulated cyclooctyne for oligonucleotide labeling by strain-promoted alkyne-azide cycloaddition, European Journal of Organic Chemistry 2014(34): 7566-7571.
- Willems Lianne I., Beenakker Thomas J.M., Murray Benjamin, Gagestein Berend, Van den Elst Hans, Van Rijssel Erwin R., Codee Jeroen D.C., Kallemeijn Wouter W., Aerts Johannes M.F.G., Van der Marel Gijsbert A. & Overkleeft Herman S. (2014), Synthesis of alpha- and beta-Galactopyranose-Configured Isomers of Cyclophellitol and Cyclophellitol Aziridine, (27): 6044-6056.
- Willems Lianne I., Jiang Jianbing, Li Kah-Yee, Witte Martin D., Kallemeijn Wouter W., Beenakker Thomas J.N., Schroeder Sybrin P., Aerts Johannes M.F.G., Van der Marel Gijsbert A., Codee Jeroen D.C. & Overkleeft Hermen S. (2014), From Covalent Glycosidase Inhibitors to Activity-Based Glycosidase Probes, Chemistry: a European Journal 20(35): 10864-10872.
- Hoogendoorn S., Puijvelde G.H.M. van, Kuiper J., Marel G.A. van der & Overkleeft H.S. (2014), A Multivalent Ligand for the Mannose-6-Phosphate Receptor for Endolysosomal Targeting of an Activity-Based Probe, Angewandte Chemie (International Edition) 53(41): 10975-10978.
- Ghisaidoobe Amar T., Van den Berg Richard J.B.H.N., Butt Saleem S., Strijland Anneke, Donker-Koopman Wilma E., Scheij Saskia, Van den Nieuwendijk Adrianus M.C.H., Koomen Gerrit-Jan, Van Loevezijn Arnold, Leemhuis Mark, Wennekes Tom, Van der Stelt Mario, Van der Marel Gijsbert A., Van Boeckel Constant A.A., Aerts Johannes M.F.G. & Overkleeft Herman S. (2014), Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors, Journal of Medicinal Chemistry 57(21): 9096-9104.
- Willems Marian M.J.H.P., Zom Gijs G., Khan Selina, Meeuwenoord Nico, Melief Cornelis J.M., Van der Stelt Mario, Overkleeft Herman S., Codee Jeroen D.C., Van der Marel Gijsbert A., Ossendorp Ferry & Filippov Dmitri V. (2014), N-Tetradecylcarbamyl Lipopeptides as Novel Agonists for Toll-like Receptor 2, Journal of Medicinal Chemistry 57(15): 6873-6878.
- Willems M.M.J.H.P., Zom G.G., Meeuwenoord N., Ossendorp F.A., Overkleeft H.S., Van der Marel G.A., Codee J.D.C. & Filippov D.V. (2014), Design, automated synthesis and immunological evaluation of NOD2-ligand-antigen conjugates, Beilstein Journal of Organic Chemistry 10: 1445-1453.
- Engelsma Sander B., Willems Lianne I., Van Paaschen Claudia E., Van Kasteren Sander I., Van der Marel Gijsbert A., Overkleeft Herman S. & Filippov Dmitri V. (2014), Acylazetine as a Dienophile in Bioorthogonal Inverse Electron-Demand Diels-Alder Ligation, 16(10): 2744-2747.
- Castelli Riccardo, Schindler Severin, Walter Sebastian M., Kniep Florian, Overkleeft Herman S., Van der Marel Gijsbert A., Huber Stefan M. & Codee Jeroen D.C. (2014), Activation of Glycosyl Halides by Halogen Bonding, Chemistry - An Asian Journal 9(8): 2095-2098.
- Laverde D., Wobser D., Romero-Saavedra F., Hogendorf W., Marel G.A. van der, Berthold M., Kropec A., Codee J.D.C. & Huebner J. (2014), Synthetic Teichoic Acid Conjugate Vaccine against Nosocomial Gram-Positive Bacteria, PLoS ONE 9(11): e110953.
- Xin Bo-Tao, De Bruin Gerjan, Verdoes Martijn, Filippov Dmitri V., Van der Marel Gijs A. & Overkleeft Herman S. (2014), Exploring dual electrophiles in peptide-based proteasome inhibitors: carbonyls and epoxides, 12(30): 5710-5718.
- Li Kah-Yee, Jiang Jianbing, Witte Martin D., Kallemeijn Wouter W., Van den Elst Hans, Wong Chung-Sing, Chander Sharina D., Hoogendoorn Sascha, Beenakker Thomas J.M., Codee Jeroen D.C., Aerts Johannes M.F.G., Van der Marel Gijs A. & Overkleeft Herman S. (2014), Synthesis of Cyclophellitol, Cyclophellitol Aziridine, and Their Tagged Derivatives, (27): 6030-6043.
- De Bruin Gerjan, Huber Eva M., Xin Bo-Tao, Van Rooden Eva J., Al-Ayed Karol, Kim Kyung-Bo, Kisselev Alexei F., Driessen Christoph, Van der Stelt Mario, Van der Marel Gijsbert A., Groll Michael & Overkleeft Herman S. (2014), Structure-Based Design of beta 1i or beta 5i Specific Inhibitors of Human Immunoproteasomes, Journal of Medicinal Chemistry 57(14): 6197-6209.
- Zom Gijs G., Khan Selina, Britten Cedrik M., Sommandas Vinod, Camps Marcel G. M., Loof Nikki M., Budden Christina F., Meeuwenoord Nico J., Filippov Dmitri V., Van der Marel Gijsbert A., Overkleeft Hermen S., Melief Cornelis J.M. & Ossendorp Ferry (2014), Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates, Cancer Immunology Research 2(8): 756-764.
- Van Rijssel Erwin R., Van Delft Pieter, Lodder Gerrit, Overkleeft Herman S., Van der Marel Gijsbert A., Filippov Dmitri V. & Codee Jeroen D.C. (2014), Furanosyl Oxocarbenium Ion Stability and Stereoselectivity, 53(39): 10381-10385.
- Guisado-Barrios Gregorio, Munoz Bianca K., Kamer Paul C.J., Lastdrager Bas, Van der Marel Gijs, Overhand Mark, Vega-Vazquez Marino & Martin-Pastor Manuel (2013), Cyclic decapeptide gramicidin S derivatives containing phosphines: novel ligands for asymmetric catalysis, Dalton Transactions 42(6): 1973-1978.
- Kistemaker Hans A.V., Noort Gerbrand J. van der Heden, Overkleeft Herman S., Van der Marel Gijsbert A. & Filippov Dmitri V. (2013), Stereoselective Ribosylation of Amino Acids, 15(9): 2306-2309.
- Frihed Tobias Gylling, Walvoort Marthe T.C., Codee Jeroen D.C., Van der Marel Gijs A., Bols Mikael & Pedersen Christian Marcus (2013), Influence of O6 in Mannosylations Using Benzylidene Protected Donors: Stereoelectronic or Conformational Effects?, Journal of Organic Chemistry (JOC) 78(6): 2191-2205.
- Castelli Riccardo, Overkleeft Herman S., Van der Marel Gijsbert A. & Codee Jeroen D.C. (2013), 2,2-Dimethyl-4-(4-methoxy-phenoxy) butanoate and 2,2-Dimethyl-4-azido Butanoate: Two New Pivaloate-ester-like Protecting Groups, 15(9): 2270-2273.
- Van Rijssel Erwin R., Goumans Theodorus P.M., Lodder Gerrit, Overkleeft Herman S., Van der Marel Gijsbert A. & Codee Jeroen D.C. (2013), Chiral Pyrroline-Based Ugi-Three-Component Reactions Are under Kinetic Control, 15(12): 3026-3029.
- Van Noort Gerbrand, Heden J. van der, Schein Catherine H., Overkleeft Herman S., Van der Marel Gijsbert A. & Filippov Dmitri V. (2013), A general synthetic method toward uridylylated picornavirus VPg proteins, 19(6): 333-336.
- Ronnols Jerk, Walvoort Marthe T.C., Van der Marel Gijsbert A., Codee Jeroen D.C. & Widmalm Goran (2013), Chair interconversion and reactivity of mannuronic acid esters, 11(46): 8127-8134.
- De Jong Ana R., Volbeda Anne G., Hagen Bas, Van den Elst Hans, Overkleeft Herman S., Van der Marel Gijsbert A. & Codee Jeroen D.C. (2013), A Second-Generation Tandem Ring-Closing Metathesis Cleavable Linker for Solid-Phase Oligosaccharide Synthesis, European Journal of Organic Chemistry 2013(29): 6644-6655.
- Otero Jose M., van der Knaap Matthijs, Llamas-Saiz Antonio L., Van Raaij Mark J., Amorin Manuel, Granja Juan R., Filippov Dmitri V., Van der Marel Gijsbert A., Overkleeft Herman S. & Overhand Mark (2013), Design, Synthesis, and Structural Analysis of Turn Modified cyclo-(alpha beta(3)alpha beta(2)alpha)(2) Peptide Derivatives toward Crystalline Hexagon-Shaped Cationic Nanochannel Assemblies, Crystal Growth & Design 13(10): 4355-4367.
- Walvoort Marthe T.C., Van der Marel Gijsbert A., Overkleeft Herman S. & Codee Jeroen D.C. (2013), On the reactivity and selectivity of donor glycosides in glycochemistry and glycobiology: trapped covalent intermediates, Chemical Science 4(3): 897-906.
- Geurink Paul P., Van der Linden Wouter A., Mirabella Anne C., Gallastegui Nerea, De Bruin Gerjan, Blom Annet E.M., Voges Mathias J., Mock Elliot D., Florea Bogdan I., Van der Marel Gijs A., Driessen Christoph, Van der Stelt Mario, Groll Michael, Overkleeft Herman S. & Kisselev Alexei F. (2013), Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites, Journal of Medicinal Chemistry 56(3): 1262-1275.
- Baggelaar M.P., Janssen F.J., Esbroeck A.C.M. van, Dulk J. den, Allara M., Hoogendoorn S., McGuire R., Florea B.I., Meeuwenoord N.J., Elst H. van den, Marel G.A. van der, Brouwer J., Marzo V. di, Overkleeft H.S. & Stelt M. van der (2013), Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-alpha in Brain, Angewandte Chemie (International Edition) 52(46): 12081-12085.
- Christina A.E., Marel G.A. van der & Codeé J.D.C. (2013), Recent developments in the construction of cis-glycosidic linkages. In: Werz D.B. & Vidal S. (red.), Modern Synthetic Methods in Carbohydrate Chemistry. From Monosaccharides to Complex Glycoconjugates: Wiley.
- Gold H., Mirzaian M., Dekker N., Joao Ferraz M., Lugtenburg J., Codee J.D.C., Marel G.A. van der, Overkleeft H.S., Linthorst G.E., Groener J.E.M., Aerts J.M.F.G. & Poorthuis B.J.H.M. (2013), Quantification of Globotriaosylsphingosine in Plasma and Urine of Fabry Patients by Stable Isotope Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry, Clinical Chemistry 59(3): 547-556.
- Gold H., Mirzaian M., Dekker N., Joao Ferraz M., Lugtenburg J., Codée J.D., Van der Marel G.A., Overkleeft H.S., Linthorst G.E., Groener J.E.M., Aerts J.M. & Poorthuis B.J.H.M. (2012), Quantification of globotriaosylsphingosine in plasma and urine of Fabry patients by stable isotope ultraperformance liquid chromatography-tandem mass spectrometry, Clinical Chemistry 59(3): 547–556.
- Nieuwendijk A.M.C.H. van den, Berg R.J.B.H.N. van den, Ruben M., Witte M.D., Brussee J., Boot R.G., Marel G.A. van der, Aerts J.M.F.G. & Overkleeft H.S. (2012), Synthesis of Eight 1-Deoxynojirimycin Isomers from a Single Chiral Cyanohydrin, European Journal of Organic Chemistry 2012(18): 3437-3446.
- Hogendorf W.F.J., Lameijer L.N., Beenakker T.J.M., Overkleeft H.S., Filippov D.V., Codee J.D.C. & Van der Marel G.A. (2012), Fluorous Linker Facilitated Synthesis of Teichoic Acid Fragments, 14(3): .
- Wennekes T., Bonger K.M., Vogel K., Van den Berg R.J.B.H.N., Strijland A., Donker-Koopman W.E., Aerts J.M.F.G., Van der Marel G.A. & Overkleeft H.S. (2012), The Development of an Aza-C-Glycoside Library Based on a Tandem Staudinger/Aza-Wittig/Ugi Three-Component Reaction, European Journal of Organic Chemistry (32): .
- Van der Heden Van Noort G.J., Van Delft P., Meeuwenoord N.J., Overkleeft H.S., Van der Marel G.A. & Filippov D.V. (2012), Fully automated sequential solid phase approach towards viral RNA-nucleopeptides, Chemical Communications 48(65): 8093-8095.
- Kallemeijn W.W., Li K.Y., Witte M.D., Marques A.R.A., Aten J., Scheij S., Jiang J., Willems L.I., Voorn-Brouwer T.M., Roomen C.P.A.A. van, Ottenhoff R., Boot R.G., Elst H. van den, Walvoort M.T.C., Florea B.I., Codee J.D.C., Marel G.A. van der, Aerts J.M.F.G. & Overkleeft H.S. (2012), Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining beta-Exoglucosidases In Situ and In Vivo, Angewandte Chemie (International Edition) 51(50): 12529-12533.
- Li J., Girard G., Florea B.I., Geurink P.P., Li N., Marel G.A. van der, Overhand M., Overkleeft H.S. & Wezel G.P. van (2012), Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach, Organic and Biomolecular Chemistry 10(43): 8677-8683.
- Walvoort M.T.C., De Witte W., Van Dijk J., Dinkelaar J., Lodder G., Overkleeft H.S., Codee J.D.C. & Van der Marel G.A. (2011), Mannopyranosyl Uronic Acid Donor Reactivity, Organic Letters 13(16): 4360-4363.
- Witte M.D., Walvoort M.T.C., Li K.Y., Kallemeijn W.W., Donker-Koopman W.E., Boot R.G., Aerts J.M.F.G., Codee J.D.C., Marel G.A. van der & Overkleeft H.S. (2011), Activity-Based Profiling of Retaining beta-Glucosidases: A Comparative Study, ChemBioChem 12(8): 1263-1269.
- Ghisaidoobe A., Bikker P., Bruijn A.C.J. de, Godschalk F.D., Rogaar E., Guijt M.C., Hagens P., Halma J.M., Hart S.M. van 't, Luitjens S.B., Rixel V.H.S. van, Wijzenbroek M., Zweegers T., Donker-Koopman W.E., Strijland A., Boot R.G., Marel G.A. van der, Overkleeft H.S., Aerts J.M.F.G. & Berg R.J.B.H.N. van den (2011), Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated Iminosugars, ACS Medicinal Chemistry Letters 2(2): 119-123.
- Gold H., Munneke S., Dinkelaar J., Overkleeft H.S., Aerts J.M.F.G., Codee J.D.C. & Van der Marel G.A. (2011), A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates, Carbohydrate Research 346(12): .
- Berg R.J.B.H.N. van den., Elst H. van den., Korevaar C.G.N., Aerts J.M.F.G., Marel G.A. van der. & Overkleeft H.S. (2011), A Rapid and Efficient Synthesis of D-erythro-Sphingosine from D-ribo-Phytosphingosine, European Journal of Organic Chemistry 2011(33): 6685-6689.
- Berg R.J.B.H.N. van den, Wennekes T., Ghisaidoobe A., Donker-Koopman W.E., Strijland A., Boot R.G., Marel G.A. van der, Aerts J.M.F.G. & Overkleeft H.S. (2011), Assessment of Partially Deoxygenated Deoxynojirimycin Derivatives as Glucosylceramide Synthase Inhibitors, ACS Medicinal Chemistry Letters 2(7): 519-522.
- Aerts J.M.F.G., Kallemeijn W.W., Wegdam W., Joao Ferraz M., Van Breemen M.J., Dekker N., Kramer G., Poorthuis B.J., Groener J.E.M., Cox-Brinkman J., Rombach S.M., Hollak C.E.M., Linthorst G.E., Witte M.D., Gold H., Marel G.A. van der, Overkleeft H.S. & Boot R.G. (2011), Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies, Journal of Inherited Metabolic Disease 34(3): 605-619.
- Gold H., Boot R.G., Aerts J.M.F.G., Overkleeft H.S., Codee J.D.C. & Marel G.A. van der (2011), A Concise Synthesis of Globotriaosylsphingosine, European Journal of Organic Chemistry (9): 1652-1663.
- Hoogendoorn S., Habets K.L., Passemard S., Kuiper J., Marel G.A. van der, Florea B.I. & Overkleeft H.S. (2011), Targeted pH-dependent fluorescent activity-based cathepsin probes, Chemical Communications 47(33): .
- Codeé J.D.C., Christina A.E., Walvoort M.T.C., Overkleeft H.S. & Marel G.A. van der (2011), Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis. In: Fraser-Reid B. & Cristóbal-López J. (red.), Reactivity Tuning in Oligosaccharide Assembly nr. 301: Springer-Verlag Berlin Heidelberg. 253-289.
- Gold H., Descroix K., Codeé J.D.C. & Marel G.A. van der (2011), Synthesis of Sugar Nucleotides: A Phosphoramidite Approach. In: Kováč P. (red.), Carbohydrate Chemistry: Proven Synthetic Methods nr. 1: CRC Press. 107-113.
- Walvoort M.T.C., Sail D., Codée J.D.C. & Marel G.A. van der (2011), Synthesis of Methyl Glycuronates by Chemo- and Regioselective TEMPO/BAIB-Oxidation. In: Kováč P. (red.), Carbohydrate Chemistry: Proven Synthetic Methods nr. 1: CRC Press. 99-106.
- Codée J.D.C., Boltje T.J. & Marel G.A. van der (2011), Diphenylsulfoxide-Trifluoromethanesulfonic Anhydride: a Potent Activator for Thioglycosides. In: Kováč P. (red.), Carbohydrate Chemistry: Proven Synthetic Methods nr. 1: CRC Press. 67-72.
- Bonger K.M., Hoogendoorn S., Van Koppen C.J., Timmers C.M., Van der Marel G.A. & Overkleeft H.S. (2011), Development of Selective LH Receptor Agonists by Heterodimerization with a FSH Receptor Antagonist, ACS Medicinal Chemistry Letters 2(1): .
- Wennekes T., Meijer A.J., Groen A.K., Boot R.G., Groener J.E., Eijk M.C. van, Ottenhoff R., Bijl N., Ghauharali K., Song H., O'Shea T.J., Liu H., Yew N., Copeland D., Berg R.J.B.H.N. van den, Marel G.A. van der, Overkleeft H.S. & Aerts J.M.F.G. (2010), Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation, Journal of Medicinal Chemistry 53(2): 689-698.
- Witte M.D., Kallemeijn W.W., Aten J., Li K.Y., Strijland A., Donker-Koopman W.E., Nieuwendijk A.M.C.H. van den, Bleijlevens B., Kramer G., Florea B.I., Hooibrink B., Hollak C.E.M., Ottenhoff R., Boot R.G., Marel G.A. van der, Overkleeft H.S. & Aerts J.M.F.G. (2010), Ultrasensitive in situ visualization of active glucocerebrosidase molecules, Nature Chemical Biology 6(12): 907-913.
- Wennekes T., Van den Berg R.J.B.H.N., Boltje T.J., Donker-Koopman W.E., Kuijper B., Van der Marel G.A., Strijland A., Verhagen C.P., Aerts J.M.F.G. & Overkleeft H.S. (2010), Synthesis and Evaluation of Lipophilic Aza-C-glycosides as Inhibitors of Glucosylceramide Metabolism, European Journal of Organic Chemistry (7): 1258-1283.
- Geurink P.P., Liu N., Spaans M.P., Downey S.L., Nieuwendijk A.M.C.H. van der, Marel G.A. van der, Kisselev A.F., Florea B.I. & Overkleeft H.S. (2010), Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome's Chymotrypsin-like Sites, Journal of Medicinal Chemistry 53(5): 2319-2323.
- Dinkelaar J., Duivenvoorden B.A., Wennekes T., Overkleeft H.S., Boot R.G., Aerts J.M.F.G., Codee J.D.C. & Van der Marel G.A. (2010), A Preparative Synthesis of Human Chitinase Fluorogenic Substrate (4'-Deoxychitobiosyl)-4-methylumbelliferone, European Journal of Organic Chemistry (13): 2565-2570.
- Nieuwendijk A.M.C.H. van, Ruben M., Engelsma S.E., Risseeuw M.D.P., Berg R.J.B.H.N. van den, Boot R.G., Aerts J.M.F.G., Brussee J., Marel G.A. van der & Overkleeft H.S. (2010), Synthesis of L-altro-1-Deoxynoprimycin, D-allo-1-Deoxynoprimycin, and D-galacto-1-Deoxynojirimycin from a Single Chiral Cyanohydrin, 12(17): 3957-3959.
- Bonger K.M., Kapoerchan V.V., Grotenbreg G.M., Van Koppen C.J., Timmers C.M., Van der Marel G.A. & Overkleeft H.S. (2010), Oligoproline helices as structurally defined scaffolds for oligomeric G protein-coupled receptor ligands, Organic and Biomolecular Chemistry 8(8): .
- Geurink P.P., Florea B.I., Van der Marel G.A., Kessler BM & Overkleeft H.S. (2010), Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates, Chemical Communications (46): 9052-9054.
- Risseeuw M.D., Florea B.I., Van der Marel G.A., Overkleeft H.S. & Overhand M. (2010), Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors, Bioorg Chem 38(5): 202-209.
- Willems L.I., Verdoes M., Florea B.I., Van der Marel G.A. & Overkleeft H.S. (2010), Two-step labeling of endogenous enzymatic activities by Diels-Alder ligation, ChemBioChem 11(12): 1769–1781.
- Hogendorf W.F., Bos L.J. van den, Overkleeft H.S., Codee J.D. & Marel G.A. van der (2010), Synthesis of an alpha-kojibiosyl substituted glycerol teichoic acid hexamer, Bioorganic & Medicinal Chemistry : .
- Walvoort M.T.C., Lodder G., Mazurek J., Overkleeft H.S., Codee J.D.C. & Marel G.A. van der (2009), Equatorial Anomeric Triflates from Mannuronic Acid Esters, Journal of the American Chemical Society 131(34): 12080-+.
- Bonger K.M., Hoogendoorn S., Van Koppen C.J., Timmers C., Overkleeft H.S. & Van der Marel G.A. (2009), Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists, ChemMedChem 4(12): 2098-2102.
- Ali A., Berg R.J.B.H.N. van den, Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codee J.D.C. (2009), Methylsulfonylethoxycarbonyl (Msc) and fluorous propylsulfonylethoxycarbonyl (FPsc) as hydroxy-protecting groups in carbohydrate chemistry, Tetrahedron Letters 50(19): 2185-2188.
- Bonger K.M., Van den Berg R., Knijnenburg A.D., Heitman L.H., Van Koppen C.J., Timmers C., Overkleeft H.S. & Marel G.A. van der (2009), Discovery of Selective Luteinizing Hormone Receptor Agonists Using the Bivalent Ligand Method, ChemMedChem 4(7): 1189-1195.
- Verdoes M., Florea B.I., Marel G.A. van der & Overkleeft H.S. (2009), Chemical Tools To Study the Proteasome, European Journal of Organic Chemistry (20): 3301-3313.
- Wennekes T., Berg R.J.B.H.N. van den, Boot R.G., Marel G.A. van der, Overkleeft H.S. & Aerts J.M.F.G. (2009), Glycosphingolipids-Nature, Function, and Pharmacological Modulation, Angewandte Chemie (International Edition) 48(47): 8848-8869.
- Codee J.D.C., Bos L.J. van den, Jong A.R. de, Dinkelaar J., Lodder G., Overkleeft H.S. & Marel G.A. van der (2009), The Stereodirecting Effect of the Glycosyl C5-Carboxylate Ester: Stereoselective Synthesis of beta-Mannuronic Acid Alginates, Journal of Organic Chemistry (JOC) 74(1): 38-47.
- Dinkelaar J., Gold H., Overkleeft H.S., Codee J.D.C. & Marel G.A. van der (2009), Synthesis of Hyaluronic Acid Oligomers using Chemoselective and One-Pot Strategies, Journal of Organic Chemistry (JOC) 74(11): 4208-4216.
- Dinkelaar J., Jong A.R. de, Meer R. van, Somers M., Lodder G., Overkleeft H.S., Codee J.D.C. & Marel G.A. van der (2009), Stereodirecting Effect of the Pyranosyl C-5 Substituent in Glycosylation Reactions, Journal of Organic Chemistry (JOC) 74(14): 4982-4991.
- Codee J.D.C., Jong A.R. de, Dinkelaar J., Overkleeft H.S. & Marel G.A. van der (2009), Stereo selectivity of glycosylations of conformationally restricted mannuronate esters, Tetrahedron 65(18): 3780-3788.
- Weterings J.J., Khan S., Heden Noort G.J. van der, Melief C.J.M., Overkleeft H.S., Burg S.H. van der, Ossendorp F., Marel G.A. van der & Filippov D.V. (2009), 2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation, Bioorganic and Medicinal Chemistry Letters 19(8): 2249-2251.
- Tuin A.W., Mol M.A.E., Van den Berg R., Fidder A., Marel G.A. van der, Overkleeft H.S. & Noort D. (2009), Activity-Based Protein Profiling Reveals Broad Reactivity of the Nerve Agent Sarin, Chemical Research in Toxicology 22(4): 683-689.
- Wennekes T., Van den Berg R., Bonger K.M., Donker-Koopman W.E., Ghisaidoobe A., Van der Marel G.A., Strijland A., Aerts J. & Overkleeft H.S. (2009), Synthesis and evaluation of dimeric lipophilic iminosugars as inhibitors of glucosylceramide metabolism, Tetrahedron Asymmetry 20(6-8): 836-846.
- Ghisaidoobe A.B.T., Koning M.C. de, Duynstee H.I., Kortenaar P.B.W., Overkleeft H.S., Filippov D.V. & Marel G.A. van der (2008), A two-step sulfurization for efficient solution-phase synthesis of phosphorothioate oligonucleotides, Tetrahedron Letters 49: 3129-3132.
- Jawalekar A.M., Meeuwenoord N.J., Cremers J.G.O., Overkleeft H.S., Marel G.A. van der, Rutjes F.P.J.T. & Delft F. van (2008), Conjugation of Nucleosides and Oligonucleotides by [3+2] Cycloaddition, Journal of Organic Chemistry (JOC) 73(1): 287-290.
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2008), Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with Celiac disease, Bioorganic & Medicinal Chemistry 16: 2053.
- Wennekes B., Lang M., Leeman M., Marel G.A. van der, Smits E., Weber M., Wiltenburg J. van, Wolberg M., Aerts J.M.F.G. & Overkleeft H.S. (2008), -scale synthesis of the glucosylceramide synthase inhibitor N-950adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin, Organic Process Research & Development : .
- Verdoes M., Florea B.I., Hillaert U., Willems L.M., Linden W.A. van der, Sae-Heng M., Filippov D.V., Kisselev A.F., Marel G.A. van der & Overkleeft H.S. (2008), Azido-BODIPY acid reveals quantitative Staudinger-Bertozzi ligation in two-step activity based proteasome profiling, ChemBioChem 9: 1735-1738.
- Heden G.J., Noort C.P. van, Verhagen C.P., Horst M.G. van der, Overkleeft H.S., Marel G.A. van der & Filippov D.V. (2008), A versatile one-pot procedure to phosphate monoesters and pyrophosphates using di(p-methoxybenzyl)-N,N-diisopropylphosphoramidite, 10: 4461-4464.
- Khan S., Weterings J.J., Britten C.M., Jong A.R. de, Graafland D., Melief C.J.M., Burg S.H. van der, Marel G.A. van der, Overkleeft H.S., Filippov D.V. & Ossendorp F.A. (2008), Chirality of TLR-2 ligand Pam(3)CysSK(4) in fully synthetic peptide conjugates critically influences the induction of specific CD8(+) T-cells, Molecular Immunology : .
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2008), Conjugation of nucleosides and oligonucleotides by [3+2] cycloaddition, Bioorganic & Medicinal Chemistry 16(4): 2053-2062.
- Dinkelaar J., Bos L.J. van den, Hogendorf W.F.J., Lodder G., Overkleeft H.S., Codee J.D.C. & Marel G.A. van der (2008), Stereoselective Synthesis of L-Guluronic Acid Alginates, Chemistry: a European Journal 14: 9400-9411.
- Gold H., Delft P. van, Meeuwenoord N.J., Codee J.D.C., Filippov D.V., Eggink G., Overkleeft H.S. & Marel G.A. van der (2008), Synthesis of Sugar Nucleotides by Application of Phosphoramidites, Journal of Organic Chemistry (JOC) 73: 9458-9460.
- Malta E., Verhagen C.P., Moolenaar G.F., Filippov D.V., Marel G.A. van der & Goosen N. (2008), Functions of base flipping in E. coli nucleotide excision repair, DNA Repair 7: 1647-1658.
- Bonger K.M., Berg R.J.B.H.N. van den, Knijnenburg A.D., Heitman L.H., IJzerman A.P., Oosterom J., Timmers C.M., Overkleeft H.S. & Marel G.A. van der (2008), Synthesis and evaluation of homodimeric GnRHR antagonists having a rigid bis-propargylated benzene core, Bioorganic & Medicinal Chemistry 16(7): 3744-3758.
- Geurink P.P., Klein T., Leeuwenburgh M.A., Marel G.A. van der, Kauffman H., Bischoff R. & Overkleeft H.S. (2008), A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity- based metalloproteinase profiling protocol, ORGANIC & BIOMOLECULAR CHEMISTRY 6: 1244.
- Bonger K.M., Wennekes T., Filippov D.V., Lodder G., Marel G.A. van der & Overkleeft H.S. (2008), The effect of Lewis acids on the stereochemistry in the Ugi three-component reaction with D-lyxo pyrroline, European Journal of Organic Chemistry : 3678-3688.
- Wennekes T., Lang B., Leeman M., Marel G.A. van der, Smits E., Weber M., Wiltenburg J. van, Wolberg M., Aerts J.M.F.G. & Overkleeft H.S. (2008), Large-scale synthesis of the glucosylceramide synthase inhibitor N[5-(adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin, Organic Process Research & Development 12(3): 414-423.
- Abello N., Geurink P.P., Toorn M. van der, Oosterhout A.J.M. van, Lugtenburg J., Marel G.A. van der, Kerstjens H.A.M., Postma D.S., Overkleeft H.S. & Bischoff R. (2008), Poly(ethylene glycol)-based stable isotope labeling reagents for the quantitative analysis of low molecular weight metabolites by LC-MS, Analytical Chemistry 80(23): 9171-9180.
- Kapoerchan V., Wiesner M., Overhand M., Marel G.A. van der, Koning F. & Overkleeft H.S. (2007), Design of azidoproline containing gluten peptides to suppress, Bioorganic & Medicinal Chemistry : .
- Bussink A.P., Swieten P.F. van, Ghauharali K., Scheij S., Eijk M.C. van, Wennekes T., Marel G.A. van der, Boot R.G., Aerts J.M.F.G. & Overkleeft H.S. (2007), N-Azidoacetylmannosamine-mediated chemical tagging of gangliosides, Journal of Lipid Research 48(6): 1417-1421.
- Kuijl C., Savage N.D.L., Marsman M., Tuin A.W., Janssen L., Egan D.A., Ketema M., Nieuwendijk A.M.C.H. van den, Eeden S.J.F. van den, Geluk A., Poot A., Marel G.A. van der, Beijersbergen R.L., Overkleeft H.S., Ottenhoff T.H.M. & Neefjes J.J. (2007), Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1, Nature 450: 725-730.
- Verdoes M., Florea B.I., Linden W.A. van der, Renou D., Nieuwendijk A.M.C.H. van den, Marel G.A. van der & Overkleeft H.S. (2007), Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors, Organic and Biomolecular Chemistry 5(9): 1416-1426.
- Swieten P.F. van, Samuel E., Hernandez R.O., Nieuwendijk A.M.C.H. van den, Leeuwenburgh M.A., Marel G.A. van der, Kessler B.M., Overkleeft H.S. & Kisselev A.F. (2007), A cell-permeable inhilbitor and activity-based probe for the caspase-like activity of the proteasome, Bioorganic and Medicinal Chemistry Letters 17(12): 3402-3405.
- Wennekes T., Berg R.J.B.H.N. van den, Donker W., Marel G.A. van der, Donker W., Marel G.A. van der, Strijland A., Aerts J.M.F.G. & Overkleeft H.S. (2007), Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man, Journal of Organic Chemistry (JOC) 72(4): 1088-1097.
- Litjens R.E.J.N., Bos L.J. van den, Codee J.D.C., Overkleeft H.S. & Marel G.A. van der (2007), The use of cyclic bifunctional protecting groups in oligosaccharide synthesis - an overview, Carbohydrate Research 342(3-4): 419-429.
- Marel G.A. van der, Bos L.J. van den, Overkleeft H.S., Litjens R.E.J.N. & Codee J.D.C. (2007), Sequential Glycosylation Strategies: A Focus on Thioglycosides as Donors and Acceptors, FRONTIERS IN MODERN CARBOHYDRATE CHEMISTRY 960: 190-208.
- Bonger K.M., Berg R.J.B.H.N. van den, Heitman L.H., IJzerman A.P., Oosterom J., Timmers C.M., Overkleeft H.S. & Marel G.A. van der (2007), Synthesis and evaluation of homo-bivalent GnRHR ligands, Bioorganic & Medicinal Chemistry 15(14): 4841-4856.
- Khan S., Bijker M.S., Weterings J.J., Tanke H.J., Adema G.J., Hall T. van, Drijfhout J.W., Melief C.J.M., Overkleeft H.S., Marel G.A. van der, Filippov D.V., Burg M.J.M. van der & Ossendorp F. (2007), Distinct Uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells, Journal of Biological Chemistry 282(29): 21145-21159.
- Bos L.J. van den, Codee J.D.C., Litjens R.E.J.N., Dinkelaar J., Overkleeft H.S. & Marel G.A. van der (2007), Uronic acids in oligosaccharide synthesis, European Journal of Organic Chemistry 24: 3963-3976.
- Yu H., Sliedregt-Bol K.M., Overkleeft H.S., Marel G.A. van der, Berkel T.J.C. van & Biessen E.A.L. (2007), Therapeutic potential of a synthetic peptide inhibitor of nuclear factor of activated T cells as antirestenotic agent, Arteriosclerosis, Thrombosis, and Vascular Biology 26(7): 1531-1537.
- Leeuwenburgh M.A., Geurink P.P., Klein T., Kauffman H.F., Marel G.A. van der, Bischoff R. & Overkleeft H.S. (2006), Solid-phase synthesis of succinylhydroxamate peptides: functionalized matrix metalloproteinase inhibitors, 8: 1705-1708.
- Weterings J.J., Khan S., Heden G.J., Drijfhout J.W., Melief C.J.M., Overkleeft H.S., Burg S.H. van der, Ossendorp F.A., Marel G.A. van der & Filippov D.V. (2006), Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: towards synthetic epitope-based vaccines, Bioorganic and Medicinal Chemistry Letters 16(12): 3258-3261.
- Dinkelaar J., Witte M.D., Bos L.J. van den, Overkleeft H.S. & Marel G.A. van der (2006), NIS/TFA: a general method for hydrolyzing thioglycosides, Carbohydrate Research 341: 1723-1729.
- Bonger K.M., Wennekes T., Lavoir S.V.P., Esposito D., Berg R.J.B.H.N. van den, Litjens R.E.J.N., Marel G.A. van der & Overkleeft H.S. (2006), Transformation of carbohydrate derived 4-azidopentanals into highly functionalized pyrrolidines via a tandem Staudinger/aza-Wittig/Ugi multicomponent reaction, QSAR & Combinatorial Science 25: 491-503.
- Bos L.J. van den, Dinkelaar J., Overkleeft H.S. & Marel G.A. van der (2006), Stereocontrolled synthesis of beta-D-mannuronic acid esters: synthesis of an alginate trisaccharide, Journal of the American Chemical Society 128: 13066-13067.
- Verdoes M., Koning M.C. de, Ghisaidoobe A.B.T., Duynstee H.I., Kortenaar P.B.W., Filippov D.V. & Marel G.A. van der (2006), Simple and efficient solution-phase synthesis of oligonucleotides using extractive work-up, Organic Process Research & Development 10: 1238-1245.
- Kriek N.M.A.J., Meeuwenoord N.J., Elst H. van den, Heus H.A., Marel G.A. van der & Filippov D.V. (2006), Chemical synthesis of picornaviral protein primers of RNA replication, ORGANIC & BIOMOLECULAR CHEMISTRY 4: 3576-3586.
- El Oualid F., Cohen L.H., Marel G.A. van der & Overhand M. (2006), Inhibitors of protein: Geranylgeranyl transferases, Current Medicinal Chemistry 13: 2385-2427.
- Tuin A.W., Siegal G.D., Marel G.A. van der, Overkleeft H.S. & Filippov D.V. (2006), Facile synthesis and application of uniformly-13C, 15N - labeled phosphotyrosine for ligand binding studies, Bioorganic and Medicinal Chemistry Letters 16(14): 3806-3808.
- Grotenbreg G.M., Buizert A.E.M., Llamas-Saiz A.L., Spalburg E., Hooft P.A.V. van, Neeling A.J., Noort D., Raaij M.J. van, Marel G.A. van der, Overkleeft H.S. & Overhand M. (2006), Beta-Turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product, Journal of the American Chemical Society 128: 7559-7565.
- Risseeuw M.D.P., Grotenbreg G.M., Witte M.D., Tuin A.W., Leeuwenburgh M.A., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2006), The synthesis of cis- and trans-fused bicyclic sugar amino acids, European Journal of Organic Chemistry 17: 3877-3886.
- Comuzzi C., Cogoi S., Overhand M., Marel G.A. van der, Overkleeft H.S. & Xodo L. (2006), Synthesis and biological evaluation of new pentaphyrin macrocycles for photodynamic therapy, Journal of Medicinal Chemistry 49: 196-204.
- Verdoes M., Florea B.I., Menendez-Benito V., Maynard C.J., Witte M.D., Van der Linden W.A., Van den Nieuwendijk A.M., Hofmann T., Berkers C.R., Van Leeuwen F.W., Groothuis T.A., Leeuwenburgh M.A., Ovaa H., Neefjes J.J., Filippov D.V., Van der Marel G.A., Dantuma N.P. & Overkleeft H.S. (2006), A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo, Chemistry & Biology 13(11): 1217-1226.
- Berg R.J.B.H.N. van den, Boltje T.J., Verhagen C.P., Litjens R.E.J.N., Marel G.A. van der & Overkleeft H.S. (2006), An efficient synthesis of the natural tetrahydrofuran pachastrissamine starting from D-ribo-phytosphingosine, Journal of Organic Chemistry (JOC) 71: 836-839.
- Koning M.C. de, Petersen L., Weterings J.J., Overhand M., Marel G.A. van der & Filippov D.V. (2006), Synthesis of thiol-modified peptide nucleic acids designed for post-assembly conjugation reactions, Tetrahedron 62: 3248-3258.
- Filippov D.V., Welters M.J.P., Valentijn A.R.P.M., Melief C.J.M., Marel G.A. van der, Burg S.H. van der, Overkleeft H.S. & Drijfhout J.W. (2006), Chemical synthesis of the HPV16 E7 protein, Tetrahedron Letters 47(52): 9349-9352.
- Roon A.M., Aguilera B., Cuenca F., Remoortere A. van, Marel G.A. van der, Deelder A.M., Overkleeft H.S. & Hokke C.H. (2005), Synthesis and antibody-binding studies of a series of parasite fuco-oligosaccharides, Bioorganic & Medicinal Chemistry 13(10): 3553-3564.
- Codee J.D.C., Stubba B., Schiattarella M., Overkleeft H.S., Boeckel C.A.A. van, Boom J.H. van & Marel G.A. van der (2005), A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy, Journal of the American Chemical Society 127(11): 3767-3773.
- Codee J.D.C., Litjens R.E.J.N., Bos L.J. van den, Overkleeft H.S. & Marel G.A. van der (2005), Thioglycosides in sequential glycosylation strategies, Chemical Society Reviews 34(9): 769-782.
- Litjens R.E.J.N., Bos L.J. van den, Codee J.D.C., Berg R.J.B.H.N. van den, Overkleeft H.S. & Marel G.A. van der (2005), Sulfonium triflate mediated glycosidations of aryl 2-azido-2-deoxy-1-thio-D-mannosides, European Journal of Organic Chemistry (5): 918-924.
- Codee J.D.C., Litjens R.E.J.N., Bos L.J. van den, Overkleeft H.S. & Marel G.A. van der (2005), Thioglycosides in sequential glycosylation strategies, Chemical Society Reviews 34(9): 769-782.
- Litjens R.E.J.N., Hoogerhout P., Filippov D.V., Codee J.D.C., Bos L.J. van den, Berg R.J.B.H.N. van den, Overkleeft H.S. & Marel G.A. van der (2005), Synthesis of an alpha-Gal epitope alpha-D-Galp-(1 -> 3)-beta-D-Galp-(1 -> 4)-beta-D-Glcp NAc-lipid conjugate, Journal of Carbohydrate Chemistry 24(7): 755-769.
- Litjens R.E.J.N., Bos L.J. van den, Codee J.D.C., Berg R.J.B.H.N. van den, Overkleeft H.S. & Marel G.A. van der (2005), Sulfonium triflate mediated glycosidations of aryl 2-azido-2-deoxy-1-thio-D-mannosides, European Journal of Organic Chemistry (5): 918-924.
- Timmer M.S.M., Risseeuw M.D.P., Verdoes M., Filippov D.V., Palisier J.R., Marel G.A. van der, Overkleeft H.S. & Boom J.H. van (2005), Synthesis of functionalized heterocycles via a tandem Staudinger/aza-Wittig/Ugi multicomponent reaction, Tetrahedron Asymmetry 16: 177-185.
- Codée J.D.C., Litjens R.E.J.N., Bos L.J. van den, Overkleeft H.S. & Marel G.A. van der (2005), Thioglycosides in sequential glycolysation strategies, Chemical Society Reviews 34: 769-782.
- Ayres L., Grotenbreg G.M., Marel G.A. van der, Overkleeft H.S., Overhand M. & Hest J.C.M. van (2005), Synthesis and controlled polymerisation of a novel Gramicidin S analogue, Macromolecular Rapid Communications 26: 1336-1340.
- Timmer M.S.M., Viciano Chumillas M., Donker-Koopman W.E., Aerts J.M.F.G., Marel G.A. van der, Overkleeft H.S. & Boom J.H. van (2005), Selective cross-metathesis of C-allyl-glycosides, Journal of Carbohydrate Chemistry 24: 335-351.
- Codée J.D.C., Stuba B., Schiatterella M., Overkleeft H.S., Boeckel C.A.A. van, Boom J.H. van & Marel G.A. van der (2005), A modular strategy towards the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy, Journal of the American Chemical Society 127: 3767-3773.
- El Oualid F., Elst H. van den, Leroy I.M., Pieterman E., Cohen L.H., Burm B.E.A., Overkleeft H.S., Marel G.A. van der & Overhand M. (2005), A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein:geranylgeranyl transferase-1, Journal Of Combinatorial Chemistry 7: 703-713.
- Lastdrager B., Timmer M.S.M., Marel G.A. van der & Overkleeft H.S. (2005), Claisen self-condensation/decarboxylation as the key steps in the synthesis of C2-symmetrical 1,7-dioxaspiro[5.5]undecanes, Tetrahedron Letters 46: 6195-6198.
- Zutphen S.M. van, Stone E.A., Rijt S. van, Robillard M.S., Marel G.A. van der, Overkleeft H.S., Dulk H. den, Brouwer J. & Reedijk J. (2005), Combinatorial discovery of new asymmetric cis platinum anticancer complexes is made possible with solid-phase synthetic methods, Journal of Inorganic Biochemistry 99(10): 2032-2038.
- Robillard M.S., Alphen S. van, Meeuwenoord N.J., Jansen B.A.J., Marel G.A. van der, Boom J.H. van & Reedijk J. (2005), Solid-phase synthesis of peptide-platinum complexes using platinum-chelating building blocks derived from amino acids, New Journal of Chemistry 29(1): 220-225.
- Zutphen S.M. van, Kraus M., Driessen C., Marel G.A. van der, Overkleeft H.S. & Reedijk J. (2005), Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity, Journal of Inorganic Biochemistry 99(6): 1384-1389.
- Voerman G., Cavalli S., Marel G.A. van der, Pfleiderer W., Boom J.H. van & Filippov D.V. (2005), Dimethyllumazine derivatives from Limnatis nilotica, 68: 938-941.
- El Oualid F., Baktawar J., Leroy I.M., Elst H. van den, Cohen L.H., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2005), Synthesis and biological evaluation of lipophilic Ca1a2L analogues as potential bisubstrate inhibitors of protein: geranylgeranyl transferase-1, Bioorganic & Medicinal Chemistry 13: 1463-1475.
- Litjens R.E.J.N., Heeten R. den, Timmer M.S.M., Overkleeft H.S. & Marel G.A. van der (2005), An expedient synthesis of the repeating unit of the acidic polysaccharide of the bacteriolytic complex of lysoamidase, Chemistry: a European Journal 11: 1010-1016.
- Litjens R.E.J.N., Bos L.J. van den, Codée J.D.C., Berg R.J.B.H.N. van den, Overkleeft H.S. & Marel G.A. van der (2005), Sulfonium triflate mediated glycosidations of aryl 2-azido-2-deoxy-1-thio-D-mannosides, European Journal of Organic Chemistry : 918-924.
- Grotenbreg G.M., Witte M.D., Hooft P.A.V. van, Spalburg E., Reiß P., Noort D., Neeling A.J., Koert U., Marel G.A. van der, Overkleeft H.S. & Overhand M. (2005), Synthesis and biological evaluation of gramicidin S dimmers, ORGANIC & BIOMOLECULAR CHEMISTRY 3: 233-238.
- Bos L.J. van den, Litjens R.E.J.N., Berg R.J.B.H.N. van den, Overkleeft H.S. & Marel G.A. van der (2005), Preparation of 1-thio uronic acid lactones and their use in oligosaccharide synthesis, 7: 2007-2010.
- Visser P.C. de, Hooft P.A.V. van, Vries A.M. de, Jong A. de, Marel G.A. van der, Overkleeft H.S. & Noort D. (2005), Biological evaluation of Tyr6 and Ser7 modified drosocin analogues, Bioorganic and Medicinal Chemistry Letters 15: 2902-2905.
- Koning M.C. de, Knaap M.S. van der, Petersen L., Elst H. van den, Marel G.A. van der, Overhand M. & Filippov D.V. (2005), Reactivity of PNA thioesters in chemical ligation reactions, SYNLETT 6: 595-598.
- Welters M.J., Filippov D.V., Eeden S.J.F. van den, Franken K.L.M.C., Nouta J., Valentijn A.R.P.M., Marel G.A. van der & Overkleeft H.S. (2004), Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV 16 E7 in the TC-1 mouse tumour model, Vaccine 23(3): 305-311.
- Swieten P.F. van, Maehr R., Nieuwendijk A.M.C.H. van den, Kessler B.M., Reich M., Wong C.S., Kalbacher H., Leeuwenburgh M.A., Driessen C., Marel G.A. van der, Ploegh H.L. & Overkleeft H.S. (2004), Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases, Bioorganic and Medicinal Chemistry Letters 14(12): 3131-3134.
- Tromp R.A., Boom S.S.G.E. van, Timmers C.M., Zutphen S. van, Marel G.A. van der, Overkleeft H.S., Boom J.H. van & Reedijk J. (2004), The beta-glucuronyl-based prodrug strategy allows for its application on beta-glucuronyl-platinum conjugates, Bioorganic and Medicinal Chemistry Letters 14(16): 4273-4276.
- Bos L.J. van den, Codee J.D.C., Toorn J.C. van der, Boltje T.J., Boom J.H. van, Overkleeft H.S. & Marel G.A. van der (2004), Thioglycuronides: Synthesis and application in the assembly of acidic oligosaccharides, 6(13): 2165-2168.
- Codee J.D.C., Bos L.J. van den, Litjens R.E.J.N., Overkleeft H.S., Boeckel C.A.A. van, Boom J.H. van & Marel G.A. van der (2004), Chemoselective glycosylations using sulfonium triflate activator systems, Tetrahedron 60(5): 1057-1064.
- Codée J.D., Overkleeft H.S., Marel G.A. van der & Boeckel C.A. van (2004), The synthesis of well-defined heparin and heparan sulfate fragments, Drug Discovery Today: Technologies 1(3): 317-26.
- Timmer M.S.M., Codee J.D.C., Overkleeft H.S., Boom J.H. van & Marel G.A. van der (2004), A tandem ring-closing metathesis cleavable linker system for solid-phase oligosaccharide synthesis, Synlett: Accounts and Rapid Communications in Chemical Synthesis (12): 2155-2158.
- Roon A.M., Pannu N.S., Vrind J.P., Marel G.A. van der, Boom J.H. van, Hokke C.H., Deelder A.M. & Abrahams J.P. (2004), Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen, Structure Fold Design 12(7): 1227-1236.
- Visser P.C. de, Helden M. van, Filippov D.V., Marel G.A. van der, Drijfhout J.W., Boom J.H. van, Noort D. & Overkleeft H.S. (2003), A novel, base-labile fluorous amine protecting group: synthesis and use as a tag in the purification of synthetic peptides, Tetrahedron Letters 44: 9013-9016.
- Kriek N.M.A.J., Kelly P., Filippov D.V., Meeuwenoord N.J., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A. & Overkleeft H.S. (2003), Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2,3-didehydroglycosides, European Journal of Organic Chemistry : 2418-2427.
- Timmer M.S.M., Verdoes M., Sliedregt L.A.J.M., Marel G.A. van der, Boom J.H. van & Overkleeft H.S. (2003), The use of a mannitol-derived fused oxacycle as a combinatorial scaffold, Journal of Organic Chemistry (JOC) 68: 9406-9411.
- Well R.M. van, Marinelli L., Erkelens K., Marel G.A. van der, Lavecchia A., Overkleeft H.S., Boom J.H. van, Kessler H. & Overhand M. (2003), Synthesis and structural analysis of cyclic oligomers consisting of furanoid and pyranoid epsilon-sugar amino acids, European Journal of Organic Chemistry : 2303-2313.
- Kriek N.M.A.J., Filippov D.V., Elst H. van den, Meeuwenoord N.J., Tesser G.I., Boom J.H. van & Marel G.A. van der (2003), Stepwise solid phasae synthesis of uridylylated viral genome-linked peptides using uridylylated amino acid building blocks, Tetrahedron 59: 1589-1597.
- Tromp R.A., Hoeven M. van der, Amore A., Brussee J., Overhand M., Marel G.A. van der & Gen A. van der (2003), Synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids from a furyl substituted chiral cyanohydrin, Tetrahedron Asymmetry 14: 1645-1652.
- Visser P.C. de, Kriek N.M.A.J., Hooft P.A.V. van, Schepdael A., Filippov D.V., Marel G.A. van der, Overkleeft H.S., Boom J.H. van & Noort D. (2003), Solid-phase synthesis of polymyxin B-1 and analogues via a safety-catch approach, JOURNAL OF PEPTIDE SCIENCE 61: 298-306.
- Leeuwenburgh M.A., Marel G.A. van der, Overkleeft H.S. & Boom J.H. van (2003), From alpha-1,2-anhydrosugars to C-glycosides: The influence of Lewis acids and nucleophiles on the stereochemistry, Journal of Carbohydrate Chemistry 22: 549-564.
- Rossenberg S.M.W. van, Sliedregt-Bol K.M., Prince P.C., Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2003), A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes, Bioconjugate Chemistry 14: 1077-1082.
- Codee J.D.C., Bos L.J. van den, Litjens R.E.J.N., Overkleeft H.S., Boom J.H. van & Marel G.A. van der (2003), Sequential one-pot glycosylations using1-hydroxyl and 1-thiodonors, 5: 1947-1950.
- Well R.M. van, Overkleeft H.S., Boom J.H. van, Coop A., Wang J.B., Wang H.Y., Marel G.A. van der & Overhand M. (2003), Synthesis of novel sugar amino acids by Curtius rearrangement, Journal of Organic Chemistry (JOC) : 1704-1710.
- Aguilera B., Ghauharali-Van der Vlugt K., Helmond M.T.J., Out J.M.M., Donker-Koopman W.E., Groener J.E.M., Boot R.G., Renkema G.H., Marel G.A. van der, Boom J.H. van, Overkleeft H.S. & Aerts J.M.F.G. (2003), Transglycosidase activity of chitotriosidase - Improved enzymatic assay for the human macrophage chitinase, Journal of Biological Chemistry 278(42): 40911-40916.
- Ovaa H., Swieten P.F. van, Kessler B.M., Leeuwenburgh M.A., Fiebiger E., Nieuwendijk A.M.C.H. van den, Galardy P.J., Marel G.A. van der, Ploegh H.L. & Overkleeft H.S. (2003), Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy, Angewandte Chemie (International Edition) 42(31): 3626-3629.
- Robillard M.S., Bacac M., Elst H. van den, Flamigni A., Marel G.A. van der, Boom J.H. van & Reedijk J. (2003), Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum (II) complexes, Journal Of Combinatorial Chemistry 5(6): 821-825.
- Zutphen S.M. van, Robillard M.S., Marel G.A. van der, Overkleeft H.S., Dulk H. den, Brouwer J. & Reedijk J. (2003), Extending solid phase methods in inorganic synthesis: the first dinuclear platinum complex synthesized via the solid phase, Chemical Communications 2003(5): 634-635.
- Robillard M.S., Davies N.P., Marel G.A. van der, Boom J.H. van, Reedijk J. & Murray V. (2003), The interaction of peptide-tethered platinum(II) complexes with DNA, Journal of Inorganic Biochemistry 86(2-3): 331-338.
- Robillard M.S., Lieth J.S., Marel G.A. van der, Boom J.H. van & Reedijk J. (2003), Application of gel-phase Pt-195 NMR spectroscopy in a novel solid-phase synthesis of a primary amine dichloroplatinum(II) complex, European Journal of Inorganic Chemistry 2003(8): 1529-1532.
- Heetebrij R.J., Kort M. de, Meeuwenoord N.J., Dulk H. den, Marel G.A. van der, Boom J.H. van & Reedijk J. (2003), A versatile approach towards regioselective platinated DNA sequences, Chemistry: a European Journal 9(8): 1823-1827.
- Bos L.J. van den, Codée J.D.C., Boom J.H. van, Overkleeft H.S. & Marel G.A. van der (2003), A novel strategy towards the synthesis of orthogonally functionalised 4-aminoglycosides, ORGANIC & BIOMOLECULAR CHEMISTRY 1: 4160.
- Koning M.C. de, Filippov D.V., Marel G.A. van der, Boom J.H. van & Overhand M. (2003), Synthesis of macrocyclic peptide nucleic acid derivatives via intramolecular chemical ligation, Tetrahedron Letters 44: 7597-7600.
- Ovaa H., Swieten P.F. van, Kessler B.M., Leeuwenburgh M.A., Fiebiger E., Nieuwendijk A.M.C.H. van den, Galardy P.J., Marel G.A. van der, Ploegh H.L. & Overkleeft H.S. (2003), Chemistry in living cells: Detection of active proteasomes by a two-step labeling strategy, Angewandte Chemie - International Edition in English 42: 3626-3629.
- Codee J.D.C., Litjens R.E.J.N., Heeten R. den, Overkleeft H.S., Boom J.H. van & Marel G.A. van der (2003), Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides, Organical Letters 5: 1519-1522.
- Rossenberg S.M.W. van, Sliedregt-Bol K.M., Koning G., Elst H. van den, Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2003), Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug, ChemBioChem 4: 633-639.
- Klein D.C.G., Jensenius M.T.H., Stamouli A., Clausen M., Kijne J., Diaz C., Sliedregt-Bol K., Marel G. van der Aartsma T., Frenken J.W.M. & Oosterkamp T.H. (2003), Towards submolecular resolution of Pisum sativum lectin by Atomic Force Microscopy with chemically functionalized tips, Biophysical Journal 84: 168A-168A.
- Turner J.J.C., Meeuwenoord N.J., Rood A.M.M., Borst P., Marel G.A. van der & Boom J.H. van (2003), Reinvestigation into the synthesis of oligonucleotides containing 5-(beta-D-glucopyranosyloxymethyl)-2'-deoxyuridine, European Journal of Organic Chemistry : 3832-3839.
- Grotenbreg G.M., Spalburg E., Neeling A. de, Marel G.A. van der, Overkleeft H.S., Boom J.H. van & Overhand M. (2003), Synthesis and biological evaluation of novel turn-modified gramicidin S analogues, Bioorganic & Medicinal Chemistry 11: 2835-2841.
- Well R.M. van, Meijer M.E.A., Overkleeft H.S., Boom J.H. van, Marel G.A. van der & Overhand M. (2003), Synthesis of bridged sugar amino acids: a new entry into conformationally locked delta- and epsilon-amino acids, Tetrahedron 59: 2423-2434.
- Filippov D.V., Zoelen D.J., Oldfield S.P., Marel G.A. van der, Overkleeft H.S., Drijfhout J.W. & Kluin-Nelemans J.C. (2003), Fluorophilic tagging reagents for solid phase peptide synthesis, Biopolymers 71: 191.
- Kriek N.M.A.J., Hout E. van der, Kelly P., Meijgaarden K.E. van, Geluk A., Ottenhoff T.H.M., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A.R.P.M. & Overkleeft H.S. (2003), Synthesis of novel tetrahydropyran-based dipeptide isosters by Overman rearrangement of 2, 3-didehydroglycosides, Eur.J.of Organic Chemistry : 2418-2427.
- Visser P.C. de, Helden M. van, Filippov D.V., Marel G.A. van der, Drijfhout J.W., Boom J.H. van, Noort D. & Overkleeft H.S. (2003), A novel, base-labile fluorous amine protecting group: synthesis and use as a tag in the purification of synthetic peptide, Tetrahedron Letters : 9013-9016.
- Kriek N.M.A.J., Hout E. van der, Kelly P., Meijgaarden K.E. van, Geluk A., Ottenhoff T.H.M., Marel G.A. van der, Overhand M., Boom J.H. van, Valentijn A.R.P.M. & Overkleeft H.S. (2003), Synthesis of novel tetrahydron-based dipeptide isosters by Overman rearrangement of 2, 3 didehydroglycosides, European Journal of Organic Chemistry 13: 2418-2427.
- Koning M.C. de, Marel G.A. van der & Overhand M. (2003), Synthetic developments towards PNA-peptide conjugates, Current Opinion in Chemical Biology 7: 734-740.
- Well R.M. van, Overkleeft H.S., Marel G.A. van der, Bruss D., Thibault G., Groot P.G. de, Boom J.H. van & Overhand M. (2003), Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors, Bioorganic and Medicinal Chemistry Letters 13(3): 331-334.
- Kriek N.M.A.J., Filippov D.V., Elst H. van den, Meeuwenoord N.J., Tesser G.I., Boom J.H. van & Marel G.A. van der (2003), Stepwise solid phase synthesis of uridylylated viral genome-linked peptides using uridylylated amino acid building blocks, Tetrahedron 59(9): 1589-1597.
- Carstensen E.V., Duynstee H.I., Marel G.A. van der, Boom J.H. van, Nielsen J., Overkleeft H.S. & Overhand M. (2003), Synthesis of highly functionalized piperidines via a tandem retro-Michael-2+3-cycloaddition, Journal of Carbohydrate Chemistry 22: 241-252.
- Burg D., Filippov D.V., Hermanns R.C.A., Marel G.A. van der, Boom J.H. van & Mulder G.J. (2002), Peptidomimetic glutathione analogues as novel γGT stable GST inhibitors, Bioorganic & Medicinal Chemistry 10: 195-205.
- Schmidt K.S., Boudvillain M., Schwartz A., Marel G.A. van der, Boom J.H. van, Reedijk J. & Lippert B. (2002), Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: A new generation of potential antisense drugs, Chemistry: a European Journal 8(24): 5566-5570.
- Verhelst S.H.L., Wiedenhof W., Ovaa H., Marel G.A. van der, Overkleeft H.S., Boeckel C.A.A. van & Boom J.H. van (2002), A stereoselective route towards highly functionalized 4,6-diaminocyclohexene derivatives, Tetrahedron Letters 43: 6451-6455.
- Ovaa H., Stapper C., Marel G.A. van der, Overkleeft H.S., Boom J.H. van & Blechert S. (2002), Ruthenium catalyzed ring rearrangement: a rapid entry to substituted aza- and oxacycles, Tetrahedron 58: 7503-7518.
- Ovaa H., Lastdrager B., Codee J.D.C., Marel G.A. van der, Overkleeft H.S. & Boom J.H. van (2002), A flexible synthesis of cyclopenditol derivatives based on ring-closing metathesis of carbohydrate-derived 1,6-dienes, Journal of the Chemical Society Perkin Transactions 1 21: 2370-2377.
- Rossenberg S.M.W. van, Sliedregt-Bol K.M., Meeuwenoord N.J., Berkel T.J.C. van, Boom J.H. van, Marel G.A. van der & Biessen E.A.L. (2002), Targeted lysosome disruptive elements for improvement of parenchymal liver cell-specific gene delivery, Journal of Biological Chemistry 277(48): 45803-45810.
- Koning M.C. de, Filippov D.V., Meeuwenoord N.J., Overhand M., Marel G.A. van der & Boom J.H. van (2002), An approach to the synthesis of peptide-PNA-peptide conjugates via native ligation, Tetrahedron Letters 43: 8173-8176.
- Filippov D.V., Zoelen D.J., Oldfield S.P., Marel G.A. van der, Overkleeft H.S., Drijfhout J.W. & Boom J.H. van (2002), Use of benzyloxycarbonyl (Z)-based fluorophilic tagging reagents in the purification of synthetic peptides, Tetrahedron Letters 43: 7809-7812.
- Codee J.D.C., Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (2002), Probing the heparin - Antithrombin III interaction using synthetic pentasaccharides bearing positively charged groups, European Journal of Organic Chemistry 23: 3954-3965.
- Burg D., Filippov D.V., Hermanns R.C.A., Marel G.A. van der, Boom J.H. van & Mulder G.J. (2002), Peptidomimetic glutathione analogues as novel gamma GT stable GST inhibitors, Bioorganic & Medicinal Chemistry 10: 195-205.
- Biessen E.A.L., Sliedregt-Bol K.M., Hoen P.A.C. 't, Prince P., Bilt E. van de, Valentijn A.R.P.M., Meeuwenoord N.J., Princen H., Bijsterbosch M.K., Marel G.A. van der, Boom J.H. van & Berkel T.J.C. van (2002), Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsal triglyceride transfer protein expression in hepatocytes, Bioconjugate Chemistry 13: 295-302.
- Eloualid F., Bruining L.D., Leroy I.M., Cohen L.H., Boom J.H. van, Marel G.A. van der, Overkleeft H.S. & Overhand M. (2002), Synthesis and biological evaluation of protein: geranylgeranyltransferase I inhibitors based on the CaaX box: Incorporation of sugar amino acids as dipeptide isosteres, Helvetica Chimica Acta 85: 3455-3472.
- Burg D., Hameetman L., Filippov D.V., Marel G.A. van der & Mulder G.J. (2002), Inhibition of glutathione S-transferase in rat hepatocytes by a glycine-tetrazole modified S-alkyl-GSH analogue, Bioorganic and Medicinal Chemistry Letters 12: 1579-1582.
- Berg R.J.B.H.N. van den, Noort D., Marel G.A. van der, Boom J.H. van & Benschop H.P. (2002), Synthesis of pseudo-disaccharide analogues of lipid A: haptens for the generation of antibodies with glycosidase activity towards lipid A, Journal of Carbohydrate Chemistry 21(3): 167-188.
- Rapozzi V., Burm B.E.A., Cogoi S., Marel G.A. van der, Boom J.H. van, Quadrifoglio F. & Xodo L. (2002), Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids, Nucleic Acids Research 30: 3712-3721.
- Berg R.J.B.H.N. van den, Korevaar C.G.N., Marel G.A. van der, Overkleeft H.S. & Boom J.H. van (2002), A simple and low cost synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine: glycosphingolipid precursors, Tetrahedron Letters 43: 8409-8412.
- Verhoeven E.E.A., Kesteren M.A. van, Turner J.J.C., Marel G.A. van der, Boom J.H. van, Moolenaar G.F. & Goosen N. (2002), The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system, Nucleic Acids Research 30: 2492-2500.
- Ovaa H., Marel G.A. van der & Boom J.H. van (2001), A convenient approach towards 2'-analogs of zoapatanol from D-glucose, Tetrahedron Letters 42: 5749-5752.
- Hooft P.A.V. van, Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (2001), Triisobutylaluminium mediated carbocyclisation of sugar derived spiroketals and ketosides, Tetrahedron Letters 42: 1769-1722.
- Robillard M., Alphen S. van, Hout E. van der, Valentijn A.R.P.M., Meeuwenoord N., Marel G.A. van der, Boom Jacques van & Reedijk J. (2001), Solid-phase synthesis of peptide-tethered platinum(II) complexes, Journal of Inorganic Biochemistry 86(1): 403-403.
- Turner J.J.C., Sikkema F.D., Filippov D.V., Marel G.A. van der & Boom J.H. van (2001), Synthesis of beta-lactams via ring opening of a serine derived aziridine, SYNLETT 11: 1727-1730.
- Iwata Y., Kort M. de, Challiss R.A.J., Marel G.A. van der, Boom J.H. van & Miyamoto S. (2001), Conformational analysis of cyclophostin and designed analogs in comparison with the potent IP3 receptor agonist adenophostin A, Drug Design and Discovery 17: 253-263.
- Tromp R.A., Hoeven M. van der, Amore A., Brussee J., Overhand M., Marel G.A. van der & Gen A. van der (2001), Chemoenzymatic synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids and their application in the synthesis of an alpha-hydroxylated beta-hexapeptide, Tetrahedron Asymmetry 12: 1109-1112.
- Soliva R., Monaco V., Gomez-Pinto I., Meeuwenoord N.J., Marel G.A. van der, Boom J.H. van, Gonzalez C. & Orozco M. (2001), Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety, Nucleic Acids Research 29: 2973-2985.
- Hooft P.A.V. van, Swieten P.F. van, Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (2001), Montmorillonite K-10 clay assisted transformation of vinylketoses into spirochromans and arylketoses, SYNLETT (2): 269-271.
- Kort M. de, Visser P.C. de, Kurzeck J., Meeuwenoord N.J., Marel G.A. van der, Ruger W. & Boom J.H. van (2001), Chemical and enzymatic synthesis of DNA fragments containing 5-(beta-D-glucopyranosyloxymethyl)-2'-deoxycytidine - a modified nucleoside in T4 phage DNA, European Journal of Organic Chemistry 11: 2075-2082.
- Koning M.C. de, Filippov D.V., Meeuwenoord N.J., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of a PNA-peptide conjugate by chemical ligation, SYNLETT 10: 1516-1518.
- Aguilera Diez M.B., Siegal G.D., Overkleeft H.S., Meeuwenoord N.J., Rutjes F.P.J.T., Hest J.C.M. van, Schoemaker H.E., Marel G.A. van der, Boom J.H. van & Overhand M. (2001), Synthesis and structural analysis of a b-hairpin modified peptide containing a sugar amino acid, European Journal of Organic Chemistry 2001(8): 1541-1574.
- Hooft P.A.V. van, Litjens R.E.J.N., Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (2001), Stereoselective transformations on D-glucose-derived eight-membered ring carbocycles, Organical Letters 3: 731-733.
- Turner J.J.C., Leeuwenburgh M.A., Marel G.A. van der & Boom J.H. van (2001), A convenient route to alpha-amino acids with beta-alkyne substituents from a serine derived aziridine, Tetrahedron Letters 42: 8713-8716.
- Timmer M.S.M., Filippov D.V., Marel G.A. van der & Boom J.H. van (2001), Synthesis of phosphorus mono- and bicycles by catalytic ring-closure metathesis, Tetrahedron Letters 42: 8231-8233.
- Sliedregt L.A.J.M., Rossenberg S.M.W. van, Autar R., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Piperi C., Merwe P.A. van der, Kuiper J., Berkel T.J.C. van & Biessen E.A. (2001), Design and synthesis of multivalent homing device for targeting to murine CD22, Bioorganic & Medicinal Chemistry 9(1): 85-97.
- Aguilera Diez M.B., Wolf L.B., Nieczypor P., Rutjes F.P.J.T., Overkleeft H.S., Hest J.C.M. van, Schoemaker H.E., Wang B., Mol J.C., Furstner A., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of diaminosuberic acid derivatives via ring-closing alkyne metathesis, Journal of Organic Chemistry (JOC) 66: 3584-3589.
- Litjens R.E.J.N., Leeuwenburgh M.A., Marel G.A. van der & Boom J.H. van (2001), A novel approach towards the stereoselective synthesis of 2-azido-2-deoxy-beta-D-mannosides, Tetrahedron Letters 42: 8693-8696.
- Turner J.J.C., Filippov D.V., Overhand M., Marel G.A. van der & Boom J.H. van (2001), Synthesis of novel amino acid carbohydrate hybrids via Mitsunobu glycosylation of nitrobenzenesulfonamides, Tetrahedron Letters 42: 5763-5767.
- Moolenaar G.F., Monaco V., Marel G.A. van der, Boom J.H. van, Visse R. & Goosen N. (2000), The effect of the DNA flanking the lesion on formation of the UvrB-DNA preincision complex - Mechanism for the UvrA-mediated loading of UvrB onto a DNA damaged site, Journal of Biological Chemistry 275(11): 8038-8043.
- Schmidt K., Sigel R.K.O., Filippov D.V., Marel G.A. van der, Lippert B. & Reedijk J. (2000), Hydrogen bonding between adenine and 2,4-difluorotoluene is definitely not present, as shown by concentration-dependent NMR studies, New Journal of Chemistry 24(4): 195-197.
- Schmidt K., Filippov D.V., Meeuwenoord N.J., Marel G.A. van der, Boom J.H. van, Lippert B. & Reedijk J. (2000), Solid-phase synthesis of a monofunctional trans-a(2)Pt(II) complex tethered to a single-stranded oligonucleotide, Angewandte Chemie (International Edition) 39(2): 375-377.
- Robillard M.S., Valentijn A.R.P.M., Meeuwenoord N.J., Marel G.A. van der, Boom J.H. van & Reedijk J. (2000), The first solid-phase synthesis of a peptide-tethered platinum(II) complex, Angewandte Chemie (International Edition) 39(17): 3096-3099.
- Ovaa H., Stragies R., Marel G.A. van der, Boom J.H. van & Blechert S. (2000), Asymmetric synthesis of indolizidine alkaloids by ring-closing-ring-opening metathesis, Chemical Communications : 1501-1502.
- Verheijen J.R., Deiman A.L.M., Yeheskiely E., Marel G.A. van der & Boom J.H. van (2000), Efficient hydrolysis of RNA by a PNA-diethylenetriamine adduct, Angewandte Chemie - International Edition in English 39(2): 369-372.
- Timmer M.S.M., Ovaa H., Filippov D.V., Marel G.A. van der & Boom J.H. van (2000), An expeditious route to phosphorus heterocycles based on ring-closing metathesis, Tetrahedron Letters 41: 8635-8638.
- Verheijen J.C., Marel G.A. van der, Boom J.H. van & Metzler-Nolte N. (2000), Transition metal derivatives of peptide nucleic acid (PNA) oligomers-synthesis, characterization, and DNA finding, Bioconjugate Chemistry 11: 741-743.
- Kort M. de, Regenbogen A.D., Overkleeft H.S., Challiss R.A.J., Iwata Y., Miyamoto S., Marel G.A. van der & Boom J.H. van (2000), Synthesis and biological evaluation of cyclophostin: A 5 ',6 ''-tethered analog of adenophostin A, Tetrahedron 56: 5915-5928.
- Kort M. de, Luijendijk J., Marel G.A. van der & Boom J.H. van (2000), Synthesis of photoaffinity derivatives of adenophostin A, European Journal of Organic Chemistry : 3085-3092.
- Moolenaar G.F., Herron M.F.P., Monaco V., Marel G.A. van der, Boom J.H. van, Visse R. & Goosen N. (2000), The role of ATP binding and hydrolysis by UvrB during nucleotide excision repair, Journal of Biological Chemistry 275(11): 8044-8050.
- Verheijen J.C., Roon A.M.M. van, Meeuwenoord N.J., Stuivenberg H.R., Bayly S.F., Chen Ling, Marel G.A. van der, Torrence P.F. & Boom J.H. van (2000), Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improves the 3 '-exonuclease stability of 2 '-5 '-oligoadenylate-antisense conjugates, Bioorganic and Medicinal Chemistry Letters 10: 801-801.
- Leeuwenburgh M.A., Litjens R.E.J.N., Codee J.D.C., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (2000), Radical cyclization of sugar-derived beta-(alkynyloxy)acrylates: Synthesis of novel fused ethers, Organical Letters 2: 1275-1277.
- Cohen L.H., Pieterman E.J., Leeuwen R.E.W. van, Overhand M., Burm B.E.A., Marel G.A. van der & Boom J.H. van (2000), Inhibitors of prenylation of Ras and other G-proteins and their application as herapeutics, Biochemical Pharmacology 60: 1061-1068.
- Verheijen J.C., Grotenbreg G.M., Ruyter L.H. de, Klein P.A.M. van der, Marel G.A. van der & Boom J.H. van (2000), An expeditious liquid-phase synthesis of cyclic peptide nucleic acids, Tetrahedron Letters 41: 3991-3995.
- Biessen E.A.L., Valentijn A.R.P.M., De Vrueh R.L., Bilt E. van de, Sliedregt L.A.J.M., Prince P.C., Bijsterbosch M.K., Boom J.H. van, Marel G.A. van der, Mulder F.E. & Berkel T.J.C. van (2000), Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl) adenine with improved pharmokinetics and antiviral activity, The FASEB Journal 14: 1784-1792.
- Kort M. de, Correa V., Valentijn A.R.P.M., Marel G.A. van der, Potter B.V.L., Taylor C.W. & Boom J.H. van (2000), Synthesis of potent agonists of the D-myo-inositol 1,4,5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A, Journal of Medicinal Chemistry 43: 3295-3303.
- Verheijen J.C., Chen Ling, Bayly S.F., Torrence P.F., Marel G.A. van der & Boom J.H. van (2000), Synthesis and RNase L binding and activation of a 2-5A-(5')-DNA-(3')-PNA chimera, a novel potential antisense molecule, Nucleotides & Nucleic Acids 19: 1821-1830.
- Kort M. de, Regenbogen A.D., Valentijn A.R.P.M., Challiss R.A.J., Iwata Y., Miyamoto S., Marel G.A. van der & Boom J.H. van (2000), Spirophostins: Conformationally restricted analogues of adenophostin A, Chemistry: a European Journal 6: 2696-2704.
- Corgoi S., Suraci C., Terra del, Diviacco S., Marel G.A. van der, Boom J.H. van, Quodrifoglio F. & Xodo L. (2000), Down-regulation of c-Li-ras promotor activity by triplex-forming oligonucleotides endogenously generated in human 293 cells, Antisense & Nucleic Acid Drug Development 10: 283-295.
- Well R.M. van, Overkleeft H.S., Overhand M., Carstenen E.V., Marel G.A. van der & Boom J.H. van (2000), Parallel synthesis of cyclic sugar amino acid/amino acid hybrid molecules, Tetrahedron Letters 41: 9331-9335.
- Leeuwenburgh M.A., Appeldoorn C.C.M., Hooft P.A.V. van, Overkleeft H.S., Marel G.A. van der & Boom J.H. van (2000), Synthesis of highly functionalised carbohydrate-derived spiroacetals by ring-closing metathesis and Pauson-Khan reaction of ketoglycosidic enynes, European Journal of Organic Chemistry : 873-877.
- Duynstee H.I., Koning M.C. de, Marel G.A. van der & Boom J.H. van (1999), An expeditious route to the synthesis of kelampayosides A and B, Tetrahedron 55: 9881.
- Heetebrij R.J., Tromp R.A., Marel G.A. van der, Boom J.H. van & Reedijk J. (1999), A novel approach to site-specifically platinated oligonucleotides applying combinations of nucleobase protecting groups, Chemical Communications 1999(17): 1693-1694.
- Ovaa H., Codee J.D.C., Lastdrager B., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1999), A versatile approach to the synthesis of highly functionalised carbocycles, Tetrahedron 40: 5063.
- Duynstee H.I., Koning M.C. de, Ovaa H., Marel G.A. van der & Boom J.H. van (1999), Synthesis of verbascoside: A dihydroxyphenylethyl glycoside with diverse bioactivity, Eur.J.of Organic Chemistry : 2623.
- Buijsman R.C., Basten J.E.M., Dreef-Tromp C.M., Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (1999), Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains, 7: 1881.
- Turner J.J.C., Wilschut N., Overkleeft H.S., Klaffke W., Marel G.A. van der & Boom J.H. van (1999), Mitsunobu glycosylation of nitrobenzenesulfonamides: Novel route to Amadori Rearrangement Products, Tetrahedron Letters 40: 7039.
- Verheijen J.C., Bayly S.F., Player M.R., Torrence P.F., Marel G.A. van der & Boom J.H. van (1999), 2-5A-PNA complexes: A novel class of antisense compounds, Nucleosides and Nucleotides 18: 1485.
- Biessen E.A.L., Bilt E. van de, Prince P., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van & Berkel T.J.C. van (1999), Tissue specific down-regulation of microsomal triglyceride tranfer protein by glycoconjugated PNA, Circulation 100: 4305-4310.
- Monaco V., Wetering K. van de, Meeuweoord N.J., Elst H.A. van den, Stuivenberg H.R., Visse R., Kaaden J. van der, Moolenaar G.F., Verhoeven E.E.A., Goosen N., Marel G.A. van der & Boom J.H. van (1999), Synthesis and biological evaluation of modified DNA fragments for the study of nucleotide excision repair in E. coli, Nucleosides and Nucleotides 18: 1339-1341.
- Sliedregt L.A.J.M., Rensen P.C.N., Rump E.T., Santbrink P.J. van, Bijsterbosch M.K., Valentijn A.R.P.M., Marel G.A. van der, Boom J.H. van, Berkel T.J.C. van & Biessen E.A.L. (1999), Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor, Journal of Medicinal Chemistry 42: 609-618.
- Overkleeft H.S., Verhelst S.H.L., Pieterman E.J., Meeuwenoord N.J., Overhand M., Cohen L.H., Marel G.A. van der & Boom J.H. van (1999), Design and synthesis of a protein : farnesyltransferase inhibitor based on sugar amino acids, Tetrahedron Letters 40: 4103.
- Van Delft F.L., Valentijn A.R.P.M., Marel G.A. van der & Boom J.H. van (1999), Preparation of 2,5-anhydrohexitols - (Part II). Intramolecular nucleophilic substitution of cyclic sulfates, J.of Carbohydrate Chemistry 18: 191.
- Leeuwenburgh M.A., Picasso S., Overkleeft H.S., Marel G.A. van der, Vogel P. & Boom J.H. van (1999), A short and flexible route to aza-beta-(1 -> 6)-C- disaccharides: Selective alpha-glycosidase inhibitors, Eur.J.of Organic Chemistry : 1185.
- Verheijen J.C., Marel G.A. van der, Boom J.H. van, Bayly S.F., Player M.R. & Torrence P.F. (1999), 2 ',5 '-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L, 7: 449.
- McCormick J., Li Y.B., McCormick K., Duynstee H.I., Van Engen A.K., Marel G.A. van der, Ganem B., Boom J.H. van & Meinwald J. (1999), Structure and total synthesis of HF-7, a neuroactive glyconucleoside disulfate from the funnel-web spider Hololena curta, J.Am.Chem.Soc. 121: 5661.
- Verheijen J.C., Van Roon A.M.M., Van der Laan A.C., Marel G.A. van der & Boom J.H. van (1999), Synthesis of DNA-(3 ')-PNA chimeras with conformationally restricted linkers based on 4-hydroxyproline, Nucleosides and Nucleotides 18: 493.
- Leeuwenburgh M.A., Kulker C., Duynstee H.I., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1999), A convenient route to cis- and trans-fused bicyclic ethers by ruthenium mediated ring-closing metathesis of diene and enyne carbohydrate derivatives, Tetrahedron 55: 8253.
- Cohen L.H., Pieterman E.J., Van Leeuwen R.E.W., Du J.R., Negre-Aminou P., Valentijn A.R.P.M., Overhand M., Marel G.A. van der & Boom J.H. van (1999), Inhibition of Human Smooth muscle Cell Proliferation in Culture by Farnesyl Pyrophosphate Analogues, Inhibitors of in Vitro Protein : Farnesyl Transferase, Biochemical Pharmacology 57: 365.
- Van Delft F.L., Valentijn A.R.P.M., Marel G.A. van der & Boom J.H. van (1999), Preparation of 2,5-anhydrohexitols - (Part I). Silicon-directed stereocontrolled cyclization, J.of Carbohydrate Chemistry 18: 165.
- Buijsman R.C., Basten J.E.M., Van Dinther J.G., Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (1999), Design and synthesis of a novel synthetic NAPAP-pentasaccharide conjugate displaying a dual antithrombotic action, 9: 2013.
- Leeuwenburgh M.A., Kulker C., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1999), Synthesis of a trans-fused tricyclic ehter using a novel differentially protected glucal, SYNLETT (12): 1945-1947.
- Kamst E., Zegelaar-Jaarsveld K., Marel G.A. van der, Boom J.H. van, Lugtenberg E.J.J. & Spaink H.P. (1999), Chemical synthesis of N-acetylglucosamine derivatives and their use as glycosyl-acceptors by the Mesorhizobium loti chitin oligosaccharides synthase NodC, Carbohydrate Research 321(3-4): 176-189.
- Kort M. de, Ebrahimi E., Wijsman E.R., Marel G.A. van der & Boom J.H. van (1999), Synthesis of oligodeoxynucleotides containing 5-(beta-D-glycopyranosyloxymethyl)-2'-deoxyuridin, a modified nucleoside in the DNA of Tyrpanosoma Brucei, European Journal of Organic Chemistry : 2337-2344.
- Cross M., Kieft R., Sabatini R., Wilm M., Kort M. de, Marel G.A. van der, Boom J.H. van, Leeuwen F. van & Borst P. (1999), The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans, The EMBO Journal 18: 6573-6581.
- Filippov D.V., Kuyl-Yeheskiely E., Marel G.A. van der, Tesser G.I. & Boom J.H. van (1998), Synthesis of a nucleopeptide fragment from poliovirus genome, Tetrahedron Letters 19: 3597-3600.
- Ippel H.H., Elst H. van den, Marel G.A. van der, Boom J.H. van & Altona C. (1998), Structural similarities and differences between H1- and H2-family DNA minihairpin loops: NMR studies of octameric minihairpins, Biopolymers 46: 375-383.
- Duynstee H.I., Vliet M.J. van, Marel G.A. van der & Boom J.H. van (1998), An efficient synthesis of (R)-3-((R)-3-(2-O-(a-L-rhamnopyranosyl)-a-L-rhamnopyranosyl)-oxydecanoyl)oxydecanoic acid, a rhamnolipid from pseudomonas aeruginosa, European Journal of Organic Chemistry : 303-308.
- Ovaa H., Codee J.D.C., Lastdrager B., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1998), A stereoselective and efficient route to (3S,4R,5S)-(+)-4,5-dihydroxy-cyclopent-1-en-3-ylamine: The side chain of the hypermodified nucleoside Q, Tetrahedron Letters 39: 7987-7990.
- Ovaa H., Leeuwenburgh M.A., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1998), An expeditious route to the synthesis of highly functionalized chiral oxepines from monosaccharides, Tetrahedron Letters 39: 3025-3028.
- Marel G.A. van der, Heskamp B.M., Boeckel C.A.A. van, Veeneman G.H. & Boom J.H. van (1998), Design and synthesis of potential fucosyl transferase inhibitors. In: Chapleur Y. (red.), Carbohydrate Mimics Concepts and Methods. Weinheim: Wiley-VCH. 491-510.
- Timmers C.M., Wigchert S.C.M., Leeuwenburgh M.A., Marel G.A. van der & Boom J.H. van (1998), Synthesis of tetrameric arabinogalactans based on 1,2-anhydrosugars, European Journal of Organic Chemistry : 91-98.
- Filippov D.V., Timmers C.M., Roerdink A.R., Marel G.A. van der & Boom J.H. van (1998), Synthesis of the antibiotically active part of agrocin 84, Tetrahedron Letters 39: 4891-4894.
- Gao Y.G., Robinson H., Guan Y., Liaw Y.C., Boom J.H. van, Marel G.A. van der & Wang A.H. (1998), Molecular structure of two crystal forms of cyclic triadenylic acid at 1A resolution, JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 16: 69-76.
- Overhand M., Stuivenberg H.R., Pieterman E.J., Cohen L.H., Leeuwen R.E.W. van, Valentijn A.R.P.M., Overkleeft H.S., Marel G.A. van der & Boom J.H. van (1998), Inhibitors of protein:farnesyl transferase and protein: geranylgeranyl transferase I: Synthesis of homologous diphosphonate analogs of isoprenylated pyrophosphate, Bioorganic chemistry 26: 269-282.
- Leeuwen F. van, Kort M. de, Marel G.A. van der, Boom J.H. van & Borst P. (1998), The modified DNA base b-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling, Analytical Biochemistry 258: 223-229.
- Timmers C.M., Straten N.C.R. van, Marel G.A. van der & Boom J.H. van (1998), An expeditious route to streptococci and enterococci glycolipids via ring-opening of 1,2-anhydrosugars with protic acids, Journal of Carbohydrate Chemistry 17: 471-487.
- Hooft P.A.V. van, Leeuwenburgh M.A., Overkleeft H.S., Marel G.A. van der, Boeckel C.A.A. van & Boom J.H. van (1998), A novel and flexible synthesis of pyranose spiroacetal derivatives, Tetrahedron Letters 39: 6061-6064.
- Duynstee H.I., Marel G.A. van der, Boom J.H. van & Koning M.C. de (1998), Synthesis of 3,4,5-trimethoxyphenyl 5"-O-caffeoyl-b-D-erythro-apiofuranosyl- (1-6)-b-D-glucopyranoside: Kelampayoside B, Tetrahedron Letters 39: 4129-4132.
- Spaink H.P., Bakkers J., Bladergroen M., Bloemberg G.V., Dandal I., Diaz C.L., Blok-Tip L., Gisel A., Harteveld M., LopezLara I.M., Kafetzopoulos D., Kamst E., Kijne J.W., Meijer D., Lugtenberg E.J.J., Ovtsyna A.O., Potrykus I., Quaedvlieg N.E.M., Quinto C., Ritsema T., Sautter C., Schlaman H.R.M., Thomas-Oates J.E., Boom J.H. van, Drift K. van der, Marel G.A. van der, Leeuwen S. van, Veldhuis A. & Wijfjes A.H.M. (1996), The molecular basis of host specificity of rhizobia. Stacey G., Mullin B. & Gresshoff P.M. (red.), Biology of Plant-Microbe Interactions. International Symposium on Molecular Plant-Microbe Interactions 14 juli 1996 - 19 juli 1996: APS PRESS. 299-306.
- Boom S.S.G.E. van, Yang D.Z., Reedijk J. & Marel G.A. van der Wang A.H.J. (1996), Structural effect of intra-strand cisplatin-crosslink on palindromic DNA sequences, Journal of Biomolecular Structure and Dynamics 13(6): 989-998.
- Bloemberg G.V., Lagas R.M., Leeuwen S. van, Marel G.A. van der, Boom J.H. van, Lugtenberg E.J.J. & Spaink H.P. (1995), Substrate specificity and kinetic studies of nodulation protein NodL of Rhizobium leuminosarum, Biochemistry 34(39): 12712-12720.
- Veer J.L. van der, Marel G.A. van der, Elst H. van den & Reedijk J. (1987), The antitumor drug cis-diamminedichloroplatinum(II) preferentially chelating neighboring guanines in the trinucleotide-d(pGpGpG), Inorganic Chemistry 26(14): 2272-2275.
- Hartog J.H.J. den, Altona C., Marel G.A. van der & Reedijk J. (1985), A H1 and P31 NMR-study of cis-Pt(NH3)2[d(CpGpG)-N7(2),N7(3)]. The influence of a 5'-terminal cytosine, on the structure of the cis-Pt(NH3)2[d(GpG)-N7,N7] intrastrand cross-link, European Journal of Biochemistry 147(2): 371-379.
- Hartog J.H.J. den, Altona C., Boom J.H. van, Marel G.A. van der, Haasnoot C.A.G. & Reedijk J. (1985), cis-diamminedichloroplatinum(II) induced distortion of a single and double stranded deoxydecanucleosidenonaphosphate studied by nuclear magnetic resonance, Journal of Biomolecular Structure and Dynamics 2(6): 1137-1155.
- Hartog J.H.J. den, Altona C., Elst H. van den, Marel G.A. van der & Reedijk J. (1985), Unwinding in an undecamer double helical DNA fragment, after binding of cis-diamminedichloroplatinum to a d(GpTpG) sequence, Inorganic Chemistry 24(7): 983-986.
- Hartog J.H.J. den, Altona C., Boom J.H. van, Marel G.A. van der, Haasnoot C.A.G. & Reedijk J. (1984), cis-Diamminedichloroplatinum(II) induced distortion in a double-helical DNA fragment, Journal of the American Chemical Society 106(5): 1528-1530.
- Hartog J.H.J. den, Altona C., Boom J.H. van, Marcelis A.T.M. Marel G.A. van der Rinkel L.J., Wille Hazeleger G. & Reedijk J. (1983), cis-platinum induced distortions in DNA. Conformational analysis of d(GpCpG) and cis-Pt(NH3)2(d(GpCpG)), studied by 500 MHZ, European Journal of Biochemistry 134(3): 485-495.
- Marcelis A.T.M., Hartog J.H.J. den, Marel G.A. van der, Wille G. & Reedijk J. (1983), Interaction of platinum compounds with short oligodeoxynucleotides containing guanine and cytosine, European Journal of Biochemistry 135(2): 343-349.