Ewa Snaar-Jagalska
Emeritus hoogleraar Cellulaire tumor biologie
- Naam
- Prof.dr. B.E. Snaar-Jagalska
- Telefoon
- +31 71 527 2727
- b.e.snaar-jagalska@biology.leidenuniv.nl
- ORCID iD
- 0000-0002-3772-047x
Voor meer informatie, zie de Engelse versie.
Postdocs
Nieuws
-
Met twee beurzen hard in de aanval om de hersentumor glioblastoom aan te pakken -
Chemotherapie zonder bijwerkingen? Het kan, met licht -
Zoektocht naar fundamentele inzichten en medicijnen tegen kanker -
Ewa Snaar-Jagalska benoemd tot hoogleraar Cellulaire tumorbiologie -
Biologiestudent Jannica Swieringa wint Unilever Researchprijs -
Agressiviteit kankercellen gestopt -
NWO TOP subsidie voor interdisciplinair project -
12 miljoen voor oogheelkundig onderzoek LUMC en partners
-
Leidse wetenschappers pakken kanker aan de basis aan
Oud-promovendi
Emeritus hoogleraar Cellulaire tumor biologie
- Wiskunde en Natuurwetenschappen
- Instituut Biologie Leiden
- IBL Animal Sciences
- Yin J., Forn Cuní G., Surendran A.M., Lopes Bastos B.M., Pouliopoulou N., Jager M.J., Le Dévédec S.E., Chen Q. & Snaar B.E. (2024), Lactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts, Angiogenesis 27: 703-717.
- Zhang L., Zhao G., Dalrymple T., Husiev Y., Bronkhorst H., Fom-Cuni G., Lopes-Bastos B.M., Snaar-Jagalska B.E. & Bonnet S.A: (2024), Cyclic ruthenium-peptide prodrugs penetrate the blood–brain barrier and attack glioblastoma upon light activation in orthotopic zebrafish tumor models, ACS Central Science 10(12): 2294-2311.
- Zhao G., Forn Cuní G., Scheers M., Lindenberg P.P., Yin J., Loosen Q. van, Passarini L., Chen L. & Snaar-Jagalska B.E. (2024), Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer, Cancer Letters 587: 216657.
- Groenewoud A., Yin J., Gelmi M.C., Alsafadi S., Nemati F., Decaudin D., Roman-Roman S., Kalirai H., Coupland S.E., Jochemsen A.G., Jager M.J. & Snaar B.E. (2023), Patient derived zebrafish xenograft models reveal ferroptosis as a fatal and druggable weakness in metastatic uveal melanoma, Cell Death Discovery 9: 183.
- Chen Q., Cuello-Garibo J.A., Bretin L.R., Zhang L., Ramu V., Aydar Y., Batsiun Y., Bronkhorst S., Husiev Y., Beztsinna N., Chen L., Zhou X.Q., Schmidt C., Ott I., Jager M.J., Brouwer A.M., Snaar-Jagalska B.E. & Bonnet S.A. (2022), Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model, Chemical Science 13(23): 6899-6919.
- Glinkina K., Groenewoud A., Teunisse A.F.A.S., Snaar-Jagalska B.E. & Jochemsen A.G. (2022), Novel treatments of uveal melanoma identified with a synthetic lethal CRISPR/Cas9 screen, Cancers 14(13): 3186.
- Groenewoud A., Forn-Cuní G., Engel B. & Snaar-Jagalska B.E. (2022), XePhIR: the zebrafish xenograft phenotype interactive repository, Database 2022: baac028.
- Li C., Ma J., Groenewoud A., Ren J., Liu S., Snaar-Jagalska B.E. & Dijke P. ten (2022), Establishment of embryonic zebrafish xenograft assays to investigate TGF-β family signaling in human breast cancer progression. In: Zi Z. & Liu X. (red.), TGF-Beta signaling. Methods in Molecular Biology nr. 2488. New York: Humana. 67-80.
- Groenewoud A., Yin J. & Snaar-Jagalska B.E. (2021), Ortho- and ectopic zebrafish xeno-engraftment of ocular melanoma to recapitulate primary tumor and experimental metastasis development, Journal of visualized experiments 175: e62356.
- Kong L., Chen Q., Campbell F., Snaar‐Jagalska E. & Kros A. (2020), Light‐triggered cancer cell specific targeting and liposomal drug delivery in a zebrafish xenograft model, Advanced Healthcare Materials 9(6): 1901489.
- Chen Q.C., Ramu V., Aydar Y., Groenewoud A., Zhou X.Q., Jager M.J., Cole H., Cameron C.G., McFarland S.A., Bonnet S. & Snaar-Jagalska B.E. (2020), TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models, Cancers 12(3): 587.
- Berning P., Hennemann C., Tulotta C., Schaefer C., Lechtape B., Hotfilder M., El Gourari Y., Jürgens H., Snaar-Jagalska B.E., Hempel G., Dirksen U. & Potratz J. (2020), The receptor tyrosine kinase RON and its isoforms as therapeutic targets in Ewing sarcoma, Cancers 12(4): 904.
- Kong L., Chen Q., Campbell F., Snaar‐Jagalska E. & Kros A. (2020), LighttTriggered cancer cell specific targeting and liposomal drug delivery in a zebrafish xenograft model, Advanced Healthcare Materials 9(6): 1901489.
- Chen L., De Menna M., Groenewoud A., Thalmann G.N., Kruithof-de Julio M. & Snaar-Jagalska B.E. (2019), A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis, Oncogene : .
- Kiener M., Chen L., Krebs M., Grosjean J., Klima I., Kalogirou Ch., Riedmiller H., Kneitz B., Thalmann G.N., Snaar-Jagalska B.E., Spahn M., Kruithof-de Julio M. & Zoni E. (2019), miR-221-5p regulates proliferation and migration in human prostate cancer cells and reduces tumor growth in vivo, BMC Cancer 19: 627.
- Heitzer E., Groenewoud A., Meditz K., Lohberger B., Liegl-Atzwanger B., Prokesch A., Kashofer K., Behrens D., Haybaeck J., Kolb-Lenz D., Koefeler H., Riedl S., Schaider H., Fischer C., Snaar-Jagalska B.E., Jong D. de, Szuhai K., Zweytick D. & Rinner B. (2019), Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization, Scientific Reports 9: 4096.
- Henderson F., Johnston H., Badrock A., Jones E., Forster D., Nagaraju R., Evangelou C., Kamarashev J., Green M., Fairclough M., Barinaga-Rementeria Ramirez I., He S., Snaar-Jagalska B.E., Hollywood K., Dunn W., Spaink H.P., Smith M., Lorigan P., Claude E., Williams K., McMahon A. & Hurlstone A. (2019), Enhanced fatty acid scavenging and glycerophospholipid metabolism accompany melanocyte neoplasia progression in zebrafish, Cancer Research 79(9): 2136-2151.
- Zoni E., Astrologo L., Ng Ch.K.Y., Piscuoglio S., Melsen J., Grosjean J., Klima I., Chen L., Snaar-Jagalska B.E., Flanagan K., Pluijm G. van der, Kloen P., Cecchini M., Kruithof-de-Julio M. & Thalmann G. (2019), Therapeutic targeting of CD146/MCAM reduces bone metastasis in prostate cancer, Molecular Cancer Research 17(5): 1013.
- Olszewski M.B., Pruszko M., Snaar-Jagalska B.E., Zylicz A. & Zylicz M. (2019), Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness, International Journal of Oncology 54(4): 1168-1182.
- Tulotta C., Groenewoud A., Snaar-Jagalska B.E. & Ottewell P. (2019), Animal models of breast cancer bone metastasis. In: Idris A.I. (red.), Bone Research Protocols. Methods in Molecular Biology nr. 1914. New York, NY, U.S.A.: Humana Press. 309-330.
- Gennaro A. di, Damiano V., Brisotto G., Armellin M., Perin T., Zucchetto A., Guardascione M., Spaink H.P., Doglioni C., Snaar-Jagalska B.E., Santarosa M. & Maestro R. (2019), Correction to: A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness, Cell Death & Differentiation 26: 2493.
- Tulotta C. & Snaar-Jagalska B.E. (2019), CXCR4 signalling, metastasis and immunotherapy: zebrafish xenograft model as translational tool for anti-cancer discovery, Journal of Cancer Metastasis and Treatment 5: 74.
- Tulotta C., Stefanescu C., Chen Q., Torraca V., Meijer A.M. & Snaar-Jagalska B.E. (2019), CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells, Scientific Reports 9: 2399.
- Gennaro A. di, Damiano V., Brisotto G., Armellin M., Perin T., Zucchetto A., Guardascione M., Spaink H.P., Doglioni C., Snaar-Jagalska B.E., Santarosa M. & Maestro R. (2018), A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness, Cell Death & Differentiation 25(12): 2165-2180.
- Karkampouna S., Helm D. van der, Gray P.C., Chen L., Klima I., Grosjean J., Burgmans M.C., Farina-Sarasqueta A., Snaar-Jagalska B.E., Stroka D.M., Terracciano L., Hoek B. van, Schaapherder A.F., Osanto S., Thalmann G.N., Verspaget H.W., Coenraad M.J. & Kruithof-de Julio M. (2018), CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma, Journal of Pathology 245(3): 297-310.
- Cao J., Pontes K.C.S., Heijkants R.C., Brouwer N.J., Groenewoud A., Jordanova E.S., Marinkovic M., Duinen S. van, Teunisse A.F.A.S., Verdijk R.M., Snaar-Jagalska B.E., Jochemsen A.G. & Jager M.J. (2018), Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target, Journal of Pathology 245(4): 433-444.
- Hill D., Chen L., Snaar-Jagalska B.E. & Chaudhry B. (2018), Embryonic zebrafish xenograft assay of human cancer metastasis, F1000Research 7: 1682.
- Paauwe M., Schoonderwoerd M.J.A., Helderman R.F.C.P., Harryvan T.J., Groenewoud A., Pelt G.W. van, Bor R., Hemmer D.M., Versteeg H.H., Snaar-Jagalska B.E., Theuer C.P., Hardwick J.C.H., Sier C.F.M., Dijke P. ten & Hawinkels L.J.A.C. (2018), Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis, Clinical Cancer Research 24(24): 6331-6344.
- Helm D. van der, Groenewoud A., Jonge-Muller E.S.M. de, Barnhoorn M.C., Schoonderwoerd M.J.A., Coenraad M.J., Hawinkels L.J.A.C., Snaar-Jagalska B.E., Hoek B. van & Verspaget H.W. (2018), Mesenchymal stromal cells prevent progression of liver fibrosis in a novel zebrafish embryo model, Scientific Reports 8(1): 16005.
- Franzetti G.A., Laud-Duval K., Ent W. van der, Brisac A., Irondelle M., Aubert S., Dirksen U., Bouvier C., Pinieux G. de, Snaar-Jagalska B.E., Chavrier P. & Delattre O. (2017), Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells, Oncogene 36: 3505-3514.
- Chen L., Groenewoud A., Tulotta C., Zoni E., Kruithof-de Julio M., Horst G. van der, Pluijm G. van der & Snaar-Jagalska B.E. (2017), A Zebrafish Xenograft Model for Studying Human Cancer Stem Cells in distant metastasis and therapy response, Methods in Cell Biology 138: 471-494.
- Liverani C., La Manna F., Groenewoud A., Mercatali L., Pluijm G. van der, Pieri F., Cavaliere D., Vita A. de, Spadazzi C., Miserocchi G., Bongiovanni A., Recine F., Riva D., Amadori D., Snaar-Jagalska B.E. & Ibrahim T. (2017), Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model, Biology Open 6: 133-140.
- Zoni E., Chen L., Karkampouna S., Granchi Z., Verhoef E.I., La Manna F., Kelber J., Pelger R.C.M., Henry M.D., Snaar-Jagalska B.E., Leenders G.J.L.H. van, Beimers L., Kloen P., Gray P.C., Pluijm G. van der & Kruithof-de Julio M. (2017), CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer, Oncogene 36: 4739-4749.
- Torraca V., Tulotta C., Snaar-Jagalska B.E. & Meijer A.H. (2017), The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme, Scientific Reports 7: 45061.
- Drabsch Y., Snaar-Jagalska B.E. & Dijke P. ten (2017), Fish Tales: The Use of Zebrafish Xenograft Human Cancer Cell Models, Histology and Histopathology 32: 673-686.
- Sousa Pontes K.C. de, Groenewoud A., Cao J., Ataide L.M.S., Snaar-Jagalska B.E. & Jager M.J. (2017), Evaluation of (fli:GFP) Casper Zebrafish Embryos as a Model for Human Conjunctival Melanoma, Investigative Ophthalmology & Visual Science 58(14): 6065-6071.
- Tulotta C., He S., Chen L., Groenewoud A., Ent W. van der, Meijer A.H., Spaink H.P. & Snaar-Jagalska B.E. (2016), Imaging of human cancer cell proliferation, invasion, and micrometastasis in a zebrafish xenogeneic engraftment model. In: Kawakami K., Patton E.E. & Orger M. (red.), Zebrafish. Methods in Molecular Biology nr. 1451. New York: Springer. 155-169.
- Yang J., Shimada Y., Olsthoorn R.R.C.L., Snaar-Jagalska B.E., Spaink H.P. & Kros A. (2016), Application of Coiled Coil Peptides in Liposomal Anti-Cancer Drug Delivery Using a Zebrafish Xenograft Model, ACS Nano 10(8): 7428-7435.
- Chen L., Groenewoud A., Pluijm G. van der & Snaar-Jagalska B.E. (2016), A zebrafish xenograft model for studying human cancer stem cells in distant metastasis and therapy response, Methods in Cell Biology 138: 471–496.
- Kovar H., Amatruda J., Brunet E., Burdach S., Cidre-Aranaz F., Alava E. de, Dirksen U., Ent W. van der, Grohar P., Grünewald T.G., Helman L., Houghton P., Iljin K., Korsching E., Ladanyi M., Lawlor E., Lessnick S., Ludwig J., Meltzer P., Metzler M., Mora J., Moriggl R., Nakamura T., Papamarkou T., Radic Sarikas B., Rédini F., Richter G.H., Rossig C., Schadler K., Schäfer B.W., Scotlandi K., Sheffield N.C., Shelat A., Snaar B.E., Sorensen P., Stegmaier K., Stewart E., Sweet-Cordero A., Szuhai K., Tirado O.M., Tirode F., Toretsky J., Tsafou K., Üren A., Zinovyev A. & Delattre O. (2016), The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease, OncoTarget 7(8): 8613-8624.
- Mercatali L., La Manna F., Groenewoud A., Casadei R., Recine F., Miserocchi G., Pieri F., Liverani C., Bongiovanni A., Spadazzi C., Vita A. de, Pluijm G. van der, Giorgini A., Biagini R., Amadori D., Ibrahim T. & Snaar-Jagalska B.E. (2016), Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model, International Journal of Molecular Sciences 17(8): 1375.
- Beletkaia E., Fenz S.A., Pomp W., Snaar-Jagalska B.E., Hogendoorn P.W.C. & Schmidt T. (2016), CXCR4 signaling is controlled by immobilization at the plasma membrane, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863(4): 607–616.
- Ent W. van der, Veneman W.J., Groenewoud A., Chen L., Tulotta C., Hogendoorn P.C., Spaink H.P. & Snaar-Jagalska B.E. (2016), Automation of Technology for Cancer Research. In: Langenau D. (red.), Cancer and Zebrafish. Advances in Experimental Medicine and Biology nr. 916. Cham: Springer. 315-332.
- Tulotta C., He S., Ent W. van der, Chen L., Groenewoud A., Spaink H.P. & Snaar-Jalaska B.E. (2016), Imaging Cancer Angiogenesis and Metastasis in a Zebrafish Embryo Model. In: Langenau D. (red.), Cancer and Zebrafish. Advances in Experimental Medicine and Biology nr. 916. Cham: Springer. 239-263.
- Tulotta C., Stefanescu C., Beletkaia E., Bussmann J., Tarbashevich K., Schmidt T. & Snaar-Jagalska B.E. (2016), Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model, Disease Models & Mechanisms 9(2): 141-153.
- Dhomen N., Marais R., Jager M.J., Snaar-Jagalska B.E., Coupland S., Romanowska-Dixon B., Mione M.C., Valente A., Ryll B., Ruijtenbeek R., Prestat A., Vinolo E. & Roman-Roman S. (2016), UM Cure 2020-A consortium of European experts in uveal melanoma to identify new therapies for patients with metastatic disease. European Journal of Cancer. 24th Biennial Congress of the European Association for Cancer Research, Manchester. 9 juli 2016 - 12 juli 2019. [conferentie poster].
- Evensen L., Johansen P.L., Koster G., Zhu K., Hefindal L., Speth M., Fenaroli F., Hildahl J., Bagherifam S., Tulota C., Prasmickaite L., Malandsmo G., Snaar-Jagalska B.E. & Griffiths G. (2015), Zebrafish as a model system for characterization of nanoparticles against cancer, Nanoscale 8(2): 862-877.
- Sand L.G.L., Scotlandi K., Berghuis D., Snaar-Jagalska B.E., Picci P., Schmidt T., Szuhai K. & Hogendoorn P.C.W. (2015), CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients, European Journal of Cancer 51(17): 2624–2633.
- Zoni E., Horst G. van der, Merbel A.F. van de, Chen L., Rane J.K., Pelger R.C.M., Collins A.T., Visakorpi T., Snaar-Jagalska B.E., Maitland N.J. & Pluijm G. van der (2015), miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of v- and 6-Integrin Expression, Cancer Research 75(11): 2326-2336.
- Ent W. van der, Burrello C., Lange M.J. de, Velden P.A. van der, Jochemsen A.G., Jager M.J. & Snaar-Jagalska B.E. (2015), Embryonic Zebrafish: Different Phenotypes after Injection of Human Uveal Melanoma Cells, Ocular Oncology and Pathology 1(3): 170-181.
- Ghotra V.P.S., He S., Horst G. van der, Nijhoff S., Bont H. de, Lekkerkerker A., Janssen R., Jenster G., Leenders G.J.L.H. van, Hoogland A., Marije M., Verhoef Esther I., Baranski Madrigal Z., Xiong J., Water B. van de, Pluijm G. van den, Snaar-Jagalska B.E. & Danen E.H.J. (2015), SYK is a candidate kinase target for the treatment of advanced prostate cancer, Cancer Research 75(1): 230-240.
- Truong H.H., Xiong J., Ghotra V.P.S., Nirmala E., Haazen L., Le Dévédec S.E., Balcioglu H.E., He S., Snaar-Jagalska B.E., Vreugdenhil E., Meerman J.H.N., Water B. van de & Danen E.H.J. (2014), beta(1) Integrin Inhibition Elicits a Prometastatic Switch Through the TGF beta-miR-200-ZEB Network in E-Cadherin-Positive Triple-Negative Breast Cancer, Science Signaling 7(312): ra15.
- Truong H.H., Xiong J., Ghotra V.P, Nirmala .E, Haazen L.C.J.M., Dévédec S.E. le, Balcioğlu H.E., He S., Snaar-Jagalska B.E., Vreugdenhil E., Meerman J.H.N., Water B. van de & Danen E.H. (2014), β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer, Science Signaling 7(312): ra15.
- Ent W. van der, Jochemsen A.G., Teunisse A.F., Krens S.G., Szuhai K., Spaink H.P., Hogendoorn P.C. & Snaar-Jagalska B.E. (2014), Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53, Journal of Pathology 223(4): 415-424.
- Ent W. van der, Burrello C., Teunisse A.F.A.S., Ksander B.R., Velden P.A. van der, Jager M.J., Jochemsen A.G. & Snaar-Jagalska B.E. (2014), Modeling of Human Uveal Melanoma in Zebrafish Xenograft Embryos, Investigative Ophthalmology & Visual Science 55(10): 6612-6622.
- Ban J., Aryee D.N., Fourtouna A., Ent W. van der, Kauer M., Niedan S., Machado I., Rodriguez-Galindo C., Tirado O.M., Schwentner R., Picci P., Flanagan A.M., Berg V., Strauss S.J., Scotlandi K., Snaar-Jagalska B.E., Lawlor E.R., Kovar H. & Llombart-Bosch A. (2014), Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma, Cancer Research 74(22): 6578-6588.
- Naber H.P., Drabsch Y.S., Snaar-Jagalska B.E., Dijke P. ten & Laar T. van (2013), Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion, Biochemical and Biophysical Research Communications 435(1): 58-63.
- Drabsch Y.S., He S., Zhang L., Snaar-Jagalska B.E. & Dijke P. ten (2013), Transforming growth factor-ß signalling controls human breast cancer metastasis in a zebrafish xenograft model, Breast Cancer Research 15: R106.
- Snaar-Jagalska B.E., Cambi A., Schmidt T. & Keijzer S. de (2013), Single molecule imaging techniques to study the dynamic regulation of GPCR function in the plasma membrane, Methods in Enzymology 521: 47-67.
- Spaink H.P., Cui C., Wiweger M.I., Jansen H.J., Veneman W.J., Marin-Juez R., Sonneville J. de, Ordas A.K., Torraca V., Ent W. van der, Leenders W.P., Meijer A.H., Snaar-Jagalska B.E. & Dirks R.P.H. (2013), Robotic injection of zebrafish embryos for high-throughput screening in disease models, Methods 62(3): 246-254.
- Rian H., Krens S.F.G., Spaink H.P. & Snaar-Jagalska B.E. (2013), Generation of Constitutive Active ERK Mutants as Tools for Cancer Research in Zebrafish, ISRN Cell Biology 2013: 867613.
- He S., Lamers G.E.M., Beenakker J.W.M., Cui C., Ghotra V.P., Danen E.H.J., Meijer A.H., Spaink H.P. & Snaar-Jagalska B.E. (2012), Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model, Journal of Pathology 227(4): 431-452.
- Camus S., Quevedo S., Menendez S., Paramonov I., Janssen R.A., Rueb S., He S., Snaar-Jagalska B.E., Laricchia-Robbio L. & Izpisua Belmonte I.C. (2012), Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angioooogenesis compounds in zebrafish, Oncogene 31: 4333-4342.
- Ghotra V.P., He S., Bont H.J.G.M. de, Ent W. van der, Spaink H.P., Water B. van de, Snaar-Jagalska B.E. & Danen E.H.J. (2012), Automated whole animal bio-imaging assay for human cancer dissemination, 7(2): e31281.
- Zhang L., Zhou F., Drabsch Y., Gao R., Snaar-Jagalska B.E., Mickanin C., Huang H., Sheppard K.A., Porter J.A. & Dijke P. ten (2012), USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor, Nature Cell Biology 14(7): 717-726.
- Serge A., Keijzer S. de, Hemert F. van, Hickman M., Hereld D., Spaink H.P., Schmidt T. & Snaar B.E. (2011), Quantification of GPCR internalization by single-molecule microscopy in living cells, Integrative Biology 3(6): 675-683.
- He S., Krens S.F.G., Zhan H., Gong Z., Hogendoorn P.C.W., Spaink H.P. & Snaar-Jagalska B.E. (2011), A deltaRaf1-ER inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures, Journal of Pathology 225(1): 19-28.
- Hemert F. van, Lazova M., Snaar-Jagalska B.E. & Schmidt T. (2010), Mobility of G proteins is heterogeneous and polarized during chemotaxis, Journal of Cell Science 123: 2922-2930.
- Kabli S., He S.N., Spaink H.P., Hurlstone A., Snaar-Jagalska B.E., Groot H.J.M. de & Alia A. (2010), In vivo magnetic resonance imaging to detect malignant melanoma in adult zebrafish, Zebrafish 7(2): 143-148.
- Schaaf M.J.M., Koopmans W., Meckel T.M., Noort S.J.T. van, Snaar B.E., Schmidt T. & Spaink H.P. (2009), Single-molecule microscopy reveals membrane microdomain organization of cells in a living vertebrate, Biophysical Journal 97(4): 1206-1214.
- Mione M., Meijer A.H., Snaar-Jagalska B.E., Spaink H.P. & Trede N.S. (2009), Disease modeling in zebrafish: cancer and immune responses. second international workshop on Zebrafish Models of Cancer and the Immune Response 20 juli 2009 - 22 juli 2009. Zebrafish 445-451.
- Snaar-Jagalska B.E. (2009), ZF-CANCER: Developing High-Throughput Bioassays for Human Cancers in Zebrafish, Zebrafish 6(4): 441-443.
- Keijzer S. de, Snaar-Jagalska B.E., Spaink H.P. & Schmidt T. (2008), Single molecule imaging of cellular signaling. In: Rigler R. & Vogel H. (red.), Single Molecules and Nanotechnology. Biophysics nr. 12. Berlin, Heidelberg: Springer-Verlag. 107-129.
- Krens S.F.G., Corredor-Adámez M., He S., Snaar-Jagalska B.E. & Spaink H.P. (2008), ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis, BMC Genomics 9: 196.
- Keijzer S. de, Sergé A., Hemert F. van, Lommerse P., Lamers G.E.M., Spaink H.P., Schmidt T. & Snaar-Jagalska B.E. (2008), A spatially restricted increase in receptor mobility is involved in directional sensing during Dictyostelium discoideum chemotaxis, Journal of Cell Science 121(10): 1750-1757.
- Krens S.F.G., He S., Lamers G.E.M., Meijer A.H., Bakkers J., Schmidt T., Spaink H.P. & Snaar-Jagalska B.E. (2008), Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation, Developmental Biology 319(2): 370-383.
- Trede N., Meijer A.H., Snaar-Jagalska B.E. & Spaink H.P. (2007), Model systems for infectious disease and cancer in zebrafish, EMBO workshop. EMBO Workshop 16 juli 2007 - 18 juli 2007. Zebrafish 287-292.
- Haupt B.J., Osbourn M., Spanhoff R., Keijzer S. de, Müller-Taubenberger A., Snaar-Jagalska B.E. & Schmidt T. (2007), Asymmetric elastic properties of Dictyostelium discoideum in relation to chemotaxis, Langmuir 23(18): 9352-9357.
- Krens S.F.G., He S., Spaink H.P. & Snaar-Jagalska B.E. (2006), Characterization and expression patterns of the MAPK family in zebrafish, Gene Expression Patterns 6(8): 1019-1026.
- Spaink H.P., Snaar-Jagalska B.E. & Meijer A.H. (2006), The innate immune system of vertebrates: challenges for future research. In: Sanchez F., Quinto C., Lopez-Lara I.M. & Geiger O. (red.), Biology of Plant-Microbe Interactions. St.Paul: I.S. for Molecular Plant-Microbe Interactions. 674-680.
- Krens S.F.G., Spaink H.P. & Snaar-Jagalska B.E. (2006), Functions of the MAPK family in vertebrate development, FEBS Letters 580(21): 4984-4990.
- He S., Salas-Vidal E., Rueb S., Krens S.F.G., Meijer A.H., Snaar-Jagalska B.E. & Spaink H.P. (2006), Genetic and transcriptome characterization of model zebrafish cell lines, Zebrafish 3(4): 441-453.
- Lommerse P.H., Snaar-Jagalska B.E., Spaink H.P. & Schmidt T. (2005), Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation, Journal of Cell Science 118(9): 1799-1809.
- Lommerse P.H., Blab G.A., Cognet L., Harms G.S., Snaar B.E., Spaink H.P. & Schmidt T. (2004), Single-molecule imaging of the h-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane, Biophysical Journal 86(1): 609-616.
- Meijer A.H., Krens S.F.G., Medina Rodriguez I.A., He S., Bitter W., Snaar-Jagalska B.E. & Spaink H.P. (2004), Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish, Molecular Immunology 40(11): 773-783.
- Snaar B.E., Krens S.F.G., Robina I., Wang L.X. & Spaink H.P. (2003), Specific activation of ERK pathways by chitin oligosaccharides in embryonic zebrafish cell lines, Glycobiology 13(10): 725-732.
- Schenk P.W., Epskamp S.J.P., Knetsch M.L.W., Harten V., Lagendijk E.L., Duijn B. van & Snaar-Jagalska B.E. (2001), Lysophosphatidic acid- and G beta-dependent activation of Dictyostelium MAP kinase ERK2, Biochemical and Biophysical Research Communications 282(3): 765-772.
- Schenk P.W. & Snaar-Jagalska B.E. (1999), Signal perception and transduction: the role of protein kinases, Biochimica et Biophysica Acta 1449(1): 1-24.
- Schenk P.W., Nebl T., Fisher P.R. & Snaar-Jagalska B.E. (1999), A serpentine receptor-dependent, G beta- and Ca2+ influx-independent pathway regulates mitogen-activated protein kinase ERK2 in Dictyostelium, Biochemical and Biophysical Research Communications 260(2): 504-509.
- Knetsch M.L.W., Heusden G.P.H. van, Ennis H.L., Shaw D.R., Epskamp S.J.P. & Snaar-Jagalska B.E. (1998), Isolation of a Dictyostelium discoideum 14-3-3 homologue which can replace the essential yeast BMH1 and BMH2 genes, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1357(2): 243-248.
- Knetsch M., Wang M., Snaar-Jagalska B.E. & Heimovaara-Dijkstra S. (1996), Abscisic Acid Induces Mitogen-Activated Protein Kinase Activation in Barley Aleurone Protoplasts, The Plant Cell 8(6): 1061-1067.
- Knetsch M.L., Epskamp S.J., Schenk P.W., Wang Y., Segall J.E. & Snaar-Jagalska B.E. (1996), Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum, The EMBO Journal 15(13): 3361-3368.
- Snaar-Jagalska B.E. & Haastert P.J. van (1994), G-protein assays in Dictyostelium, Methods in Enzymology 237: 387-408.
- Wang M., Sedee N.J., Heidekamp F. & Snaar-Jagalska B.E. (1993), Detection of GTP-binding proteins in barley aleurone protoplasts, FEBS Letters 329(3): 245-248.
- Ludérus M.E., Kesbeke F., Knetsch M.L., Driel R. van, Reymond C.D. & Snaar-Jagalska B.E. (1992), Ligand-independent reduction of cAMP receptors in Dictyostelium discoideum cells over-expressing a mutated ras gene, European Journal of Biochemistry 208(2): 235-240.
- Peters D.J., Snaar-Jagalska B.E., Haastert P.J. van & Schaap P. (1992), Lithium, an inhibitor of cAMP-induced inositol 1,4,5-trisphosphate accumulation in Dictyostelium discoideum, inhibits activation of guanine-nucleotide-binding regulatory proteins, reduces activation of adenylylcyclase, but potentiates activation of guanylyl cyclase by cAMP, European Journal of Biochemistry 209(1): 299-304.
- Bominaar A.A., Kesbeke F., Snaar-Jagalska B.E., Peters D.J., Schaap P. & Haastert P.J. van (1991), Abberant chemotaxis and differentiation in Dictyostelium mutant fgdC with a defective regulation of receptor-stimulated phosphoinositidase C, Journal of Cell Science 100(4): 825-831.
- Snaar-Jagalska B.E., Es S. van, Kesbeke F. & Haastert P.J. van (1991), Activation of a pertussis-toxin-sensitive guanine-nucleotide-binding regulatory protein during desensitization of Dictyostelium discoideum cells to chemotactic signals, FEBS Journal 195(3): 715-721.
- Schenk P.W., Es S. van, Kesbeke F. & Snaar-Jagalska B.E. (1991), Involvement of cyclic AMP cell surface receptors and G-proteins in signal transduction during slug migration of Dictyostelium discoideum, Developmental Biology 145(1): 110-118.
- Peters D.J., Bominaar A.A., Snaar-Jagalska B.E., Brandt R., Haastert P.J. van, Ceccarelli A., Williams J.G. & Schaap P. (1991), Selective induction of gene expression and second-messenger accumulation in Dictyostelium discoideum by the partial chemotactic antagonist 8-p-chlorophenylthioadenosine 3',5'-cyclic monophosphate, Proceedings of the National Academy of Sciences 88(20): 9219-9223.
- Bominaar A.A., Kaay J. van der, Kesbeke F., Snaar-Jagalska B.E. & Haastert P.J. van (1990), G-proteins and the inositol cycle in Dictyostelium discoideum, Biochemical Society Symposia 56: 71-80.
- Snaar-Jagalska B.E. & Haastert P.J. van (1990), Pertussis toxin inhibits cAMP-induced desensitization of adenylate cyclase in Dictyostelium discoideum, Molecular and Cellular Biochemistry 92(2): 177-189.
- Kesbeke F., Haastert P.J.M. van, Wit R.J.W. de & Snaar-Jagalska B.E. (1990), Chemotaxis to cyclic AMP and folic acid is mediated by different G proteins in Dictyostelium discoideum, Journal of Cell Science 96: 669-673.
- Haastert P.J.M. van, Bominaar A.A., Kaay J. van der, Drayer R., Penning L.C., Roovers E., Vries M.M. de, Vink A.A., Kesbeke F. & Snaar-Jagalska B.E. (1990), The inositolcycle of Dictyostelium discoideum. In: Konijn T.M., Houslay M.D. & Haastert P.J.M. van (red.), Activation and Desensitization of Transducing Pathways nr. NATO ASI Series H Cell Biology. Berlin, Heidelberg: Springer Verlag. 41-59.
- Bominaar A.A., Snaar-Jagalska B.E., Kesbeke F. & Haastert P.J.M. van (1989), Signal-transducing G-proteins in Dictyostelium discoideum. In: Bosch L., Kraal B. & Parmeggiani A. (red.), The Guanine Nucleotide Binding Proteins. Common Structural and Functional Properties nr. NATO ASI Series A. Boston, MA: Springer. 369-375.
- Snaar-Jagalska B.E., Jakobs K.H. & Haastert P.J. van (1988), Agonist-stimulated high-affinity GTPase in Dictyostelium membranes, FEBS Letters 236(1): 139-144.
- Snaar-Jagalska B.E. & Haastert P.J.M. van (1988), Dictyostelium discoideum mutant synag 7 with altered G-protein-adenylate cyclase interaction, Journal of Cell Science 91: 287-294.
- Snaar-Jagalska B.E., Kesbeke F.M.H.N. & Haastert P.J. van (1988), G-proteins in the signal-transduction pathways of Dictyostelium discoideum, Genesis: The Journal of Genetics and Development 9(4-5): 215-226.
- Snaar-Jagalska B.E., Kesbeke F., Pupillo M. & Haastert P.J. van (1988), Immunological detection of G-protein alpha-subunits in Dictyostelium discoideum, Biochemical and Biophysical Research Communications 156(2): 757-761.
- Snaar-Jagalska B.E., Devreotes P.N. & Haastert P.J.M. van (1988), Ligand-induced modification of a surface cAMP receptor of Dictyostelium discoideum does not require its occupancy, Journal of Biological Chemistry 263(2): 897-901.
- Snaar-Jagalska B.E., Wit R.J. de & Haastert P.J. van (1988), Pertussis toxin inhibits cAMP surface receptor-stimulated binding of [35S]GTP gamma S to Dictyostelium discoideum membranes, FEBS Letters 232(1): 148-152.
- Kesbeke F., Snaar-Jagalska B.E. & Haastert P.J. van (1988), Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein, Journal of Cell Biology 107(2): 521-528.
- Haastert P.J. van, Snaar-Jagalska B.E. & Janssens P.M. (1987), The regulation of adenylate cyclase by guanine nucleotides in Dictyostelium discoideum membranes, European Journal of Biochemistry 162(2): 251-258.
- Haastert P.J.M. van, Wit R.J.W. de, Janssens P.M.W., Kesbeke F., Snaar-Jagalska B.E., Lookeren Campagne M.M. van & Konijn T.M. (1987), Adaptation of Dictostelium discoideum cells to chemotactic signals. In: Konijn T.M., Haastert P.J.M. van, Starre H. van der, Wel H. van der & Houslay M.D. (red.), Molecular mechanisms of desensitization to signal molecules. NATO ASI Series (Series H: Cell Biology) nr. Volume 6. Heidelberg, F.R.G.: Springer Verlag. 25-42.
- Franssen J.M., Snaar-Jagalska B.E. & Hulst C.T.C. van der (1986), The development of Elisa to determine abscisic acid and indole-3-acetic acid in bulbous crops, Acta Horticulturae 177: 563-567.
- Wit R.J. de & Snaar-Jagalska B.E. (1985), Folate and cAMP modulate GTP binding to isolated membranes of Dictyostelium discoideum. Functional coupling between cell surface receptors and G-proteins, Biochemical and Biophysical Research Communications 129(1): 11-17.
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