The Faculty of Science and the Leiden Academic Centre for Drug Research (LACDR) are looking for a:

Postdoctoral candidate for chemically defined synthetic antibody development

Do you want to develop top edge novel drug modalities, embedded in a young and enthusiastic research group? With us you will combine organic synthesis, solid phase synthesis, polymerization and bioconjugation techniques to develop novel nanomaterials that mimic therapeutic antibodies in size, shape and function. Your work at the interface of chemistry and biology will prepare you for a competitive scientific career, both in academia and in the industry. Join our team in the https://pomplunlab.com at Leiden University! The project is performed as an exciting collaboration with the https://barzlab.com/ , increasing the potential for networking and learning experiences.

Project objectives

• Develop synthesis strategies for sequences defined polymers
• Develop conjugation strategies for peptide (or small molecules) onto polymers
• Develop biophysical characterization assays (binding assays, microscopy, etc.) for the nanomaterials

Selection criteria

• PhD in Chemistry, Medicinal Chemistry, Chemical Biology, Biochemistry or related with a robust chemistry training
• Research experience with organic chemistry. Expertise in solid phase synthesis and bioconjugation techniques are strong benefit. Experience with biochemical binding assays and protein handling are of advantage.
• Scientific interest, dedication to research, creative thinking, goal oriented mentality
• Proven publication track record in peer reviewed scientific journals
• Appreciation for interdisciplinarity and proactive drive to collaborate across fields
• Proficiency in English, good communication skill and social competence

What we offer:
You will work in the modern laboratories of the Leiden Academic Centre for Drug research (LACDR). State of the art equipment for the project is available (automated synthesizers, high resolution mass spectrometers, automated flash chromatography, biolayer interferometry, etc.). You will receive supportive supervision both for your project, the publication process and your future career.

Terms and conditions
We offer a full-time appointment of initially one year. After a positive evaluation of the progress of the research, teaching evaluations, personal capabilities and compatibility, the appointment will be extended for another two years. You will be appointed in accordance with the Collective Labour Agreement for Dutch Universities. The salary ranges from € 3.345 - € 5.278 gross per month, depending on experience (pay scale 10).

Leiden University has good employment conditions. For example, there is an end-of-year bonus (8.3%), holiday allowance (8%), excellent training facilities, paid parental leave and the option to choose tailor-made employment conditions via a selection model. You can find all information about this at https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions.

Candidates from outside the Netherlands may be eligible for a substantial tax break.

Diversity and inclusion
Diversity and inclusion are core values of Leiden University. Leiden University is committed to becoming an inclusive community which enables all students and staff to feel valued and respected and to develop their full potential.

Faculty
The Faculty of Science at Leiden University is a world-class faculty where staff and students work together in a dynamic international environment. It is a faculty where personal and academic development are top priorities. Our people are committed to expand fundamental knowledge by curiosity and to look beyond the borders of their own discipline; their aim is to benefit science, and to make a contribution to addressing the major societal challenges of the future.

The research carried out at the Faculty of Science is very diverse, ranging from mathematics, information science, astronomy, physics, chemistry and bio-pharmaceutical sciences to biology and environmental sciences. The research activities are organized in eight institutes. These institutes offer eight bachelors’ and twelve master’s programs. The faculty has grown strongly in recent years and now has more than 2,300 staff and over 5,000 students. We are located at the heart of Leiden’s Bio Science Park, one of Europe’s biggest science parks, where university and business life come together.

University
Leiden University is one of Europe’s leading international research universities.

Thanks to its committed and inspired employees, the university enjoys a leading role in academic research and education. Leiden also scores very well every year in prominent rankings. This means that, to maintain our position, the bar is set very high. Regardless of the work you do at our university, you are always encouraged to broaden your horizons, develop your talents and reach your full potential. Will you become our newest colleague?

Information
If you have questions about this position, please contact Dr. Sebastian Pomplun, s.j.pomplun@lacdr.leidenuniv.nl.

Applications
Are you enthusiastic about this vacancy? We are looking forward to get to know you. Please submit your application online through the blue button below. Please ensure that you upload the following additional documents:

• Applications are written in English and include a Cover Letter indicating the motivation for the project
• Curriculum vitae with publication list
• Copies of transcripts of degrees obtained
• Contact details of two references

Applications should be submitted as a single pdf file by 15th October 2024