Tim Ofman
Onderzoeker
- Naam
- Dr. T.P. Ofman
- Telefoon
- +31 71 527 4481
- t.p.ofman@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-1687-2191
Onderzoeker
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Bio-organic Synthesis
- Ofman T.P. (28 maart 2024), Design and synthesis of next generation carbohydrate-mimetic cyclitols : towards deactivators of inverting glycosidases and glycosyl transferases (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Promotor(en): Overkleeft H.S. & Codée J.D.C.
- Ofman T.P., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2023), Design and synthesis of exocyclic cyclitol aziridines as potential mechanism-based glycosidase inactivators, European Journal of Organic Chemistry 26(16): e202300186.
- Ofman T.P., Küllmer F., Marel G.A. van der, Codée J.D.C. & Overkleeft H.S. (2021), An orthogonally protected cyclitol for the construction of nigerose- and dextran-mimetic cyclophellitols, Organic Letters 23(24): 9516-9519.
- Hansen T., Ofman T.P., Vlaming J.G.C., Gagarinov I.A., Beek J. van, Goté T.A., Tichem J.M., Ruijgrok G., Overkleeft H.S., Filippov D.V., Marel G.A. van der & Codée J.D.C. (2020), Reactivity-stereoselectivity mapping for the assembly of Mycobacterium marinum lipooligosaccharides, Angewandte Chemie (International Edition) 60(2): 937-945.
- Zhou J., Mock E.D., Al Ayed K., Di X., Kantae V., Burggraaff L., Stevens A.F., Martella A., Mohr F., Jiang M., Wel T. van der, Wendel T.J., Ofman T.P., Tran Y., Koster N. de, Westen G.J.P. van, Hankemeier T. & Stelt M. van der (2020), Structure-Activity Relationship Studies of α-Ketoamides as Inhibitors of the Phospholipase A and Acyltransferase Enzyme Family, Journal of Medicinal Chemistry 63(17): 9340-9359.