Thomas Huizinga
Hoogleraar Reumatologie
- Naam
- Prof.dr. T.W.J. Huizinga
- Telefoon
- +31 71 526 3595
- t.w.j.huizinga@lumc.nl
- ORCID iD
- 0000-0001-7033-7520
Tom W.J. Huizinga is hoogleraar reumatologie, afdelingshoofd van de afdeling reumatologie en plaatsvervangend opleider reumatologie. Hij is voorzitter van de stichting Meteor waarin ziekteactiviteit en medicatiegegevens geregistreerd worden van Reumatoïde artritis-patiënten uit meer dan 20 landen en van de Nascholings Commissie Reumatologie van de NVR/Boerhaave. Hij is PI/coordinator van de ERC-Synergy grant Glycanswitch 2023-2029
Meer informatie over Thomas Huizinga
Tom W.J. Huizinga is hoogleraar reumatologie, afdelingshoofd van de afdeling reumatologie en plaatsvervangend opleider reumatologie. Hij is voorzitter van de stichting Meteor waarin ziekteactiviteit en medicatiegegevens geregistreerd worden van Reumatoïde artritis-patiënten uit meer dan 20 landen en van de Nascholings Commissie Reumatologie van de NVR/Boerhaave. Hij is PI/coordinator van de ERC-Synergy grant Glycanswitch 2023-2029
Reumatologie
Reumatologie bestudeert de ziektes van het bewegingsapparaat waarbij het normale functioneren belemmerd wordt door ontsteking van de gewrichten. Huizinga is met name geïnteresseerd in het begrijpen van de pathogenese waardoor de herkenning en behandeling van patiënten verbeterd. Zijn meest directe betrokkenheid is bij de ziektes Reumatoïde artritis (RA) en Systemische lupus erythematosus (SLE)
Wetenschappelijke carrière
Tom W.J. Huizinga heeft zijn opleiding geneeskunde en promotie gedaan aan de Universiteit van Amsterdam. De titel van zijn proefschrift (1989, cum laude) luidt 'Neutrophil Fc-gamma receptors'. Vervolgens deed hij onderzoek in Dartmouth Medical School, New Hampshire, USA en specialiseerde hij zich in Leiden tot reumatoloog. Hij werd in 2000 benoemd tot hoogleraar reumatologie aan het Leids Universitair Medisch Centrum. De titel van zijn oratie is Experimentele Reumatologie.
Al meer dan 30 jaar doet Huizinga onderzoek naar de pathogenese, diagnostiek en behandeling van reumatologische ziekten. Hij heeft meer dan 750 wetenschappelijke publikaties en meer dan 20 boekhoofdstukken op zijn naam staan. Zijn H-index 8-2-18 is 90. Hij bekleedde een aantal nationale en internationale functies bij wetenschappelijke organisaties. Huizinga is actief in de redactieraad van Plos Medicine, Annals of Rheumatic Diseases, Arthritis Rheumatism, Joint Bone Spine Revue du Rheumatism, European Journal for Clinical Investigation, Journal of Clinical Rheumatology and Musculoskeletal Medicine, Autoimmunity Highlights and Current Rheumatology Review.
Huizinga schreef onder andere mee aan de nieuwe 2010 criteria voor RA en aan de EULAR guidelines voor de behandeling van RA.
Prijzen en eervolle benoemingen
Tom W.J. Huizinga won meerdere prijzen waaronder de Boerhaave-prijs 1994 'for young scientists because of outstanding contributions to Immunology', in 1996 de 'European League against Rheumatism (EULAR) young investigator award', in 1997 de Amerikaanse 'Howard and Martha Holley Award', in 2009 de 'Willy van Heuman-award for generation of in-vitro models as alternatives for animal-models' and in 2011 de 'Eurolife Distuinguished Faculty Lecture Medal' uitgereikt door het Karolinska Instituut in Stockholm Zweden.
Hoogleraar Reumatologie
- Faculteit Geneeskunde
- Divisie 2
- Reumatologie
- del-Pino, R.A.; Monahan, R.C.; Huizinga, T.W.J.; Eikenboom, J. & Steup-Beekman, G.M. (2024), Risk factors for antiphospholipid antibodies and antiphospholipid syndrome, Seminars in Thrombosis and Hemostasis.
- Ouwerkerk, L. van; Bergstra, S.A.; Maarseveen, T.D.; Huizinga, T.W.J.; Knevel, R. & Allaart, C.F. (2024), Is glucocorticoid bridging therapy associated with later use of glucocorticoids and biological DMARDs during the disease course of patients with rheumatoid arthritis in daily practice?, Seminars in Arthritis and Rheumatism 64.
- Manaï, M.; Middendorp, H. van; Pol, J.A. van der; Allaart, C.F.; Dusseldorp, E.; Veldhuijzen, D.S.; Huizinga, T.W.J. & Evers, A.W.M. (2024), Can pharmacological conditioning as an add-on treatment optimize standard pharmacological treatment in patients with recent-onset rheumatoid arthritis? , Pharmaceuticals 17(1).
- Ciaffi, J.; Liem, S.I.E.; Cannegieter, S.; Ahmed, S.; Hoekstra, E.M.; Wiland, P.; Atsumi, T.; Szücs, G.; Gurman, A.B.; Czirják, L.; Zanatta, E.; Koetter, I.; Henes, J.C.; Matucci-Cerinic, M.; Airò, P.; Ursini, F.; Huizinga, T.W.J.; Vries-Bouwstra, J. de & Eustar Collaborators (2024), Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort, RMD Open: Rheumatic and Musculoskeletal Diseases 10(2).
- Hoekstra, E.M.; Liem, S.I.E.; Ahmed, S.; Levarht, N.; Fehres, C.M.; Giuca, A.; Marsan, N.A.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2024), Troponin I levels in systemic sclerosis patients with myocardial involvement, Journal of Scleroderma and Related Disorders.
- Pol, J.A. van der; Allaart, C.F.; Lems, W.; Kooij, S.M. van der; Huizinga, T.W.J. & Bergstra, S.A. (2024), Prednisone use, disease activity and the occurrence of hyperglycaemia and diabetes in patients with early rheumatoid arthritis, RMD Open: Rheumatic and Musculoskeletal Diseases 10(2).
- Stork, E.M.; Rijswijck, D.M.H. van; Schie, K.A. van; Hoek, M.; Kissel, T.; Scherer, H.U.; Huizinga, T.W.J.; Heck, A.J.R.; Toes, R.E.M. & Bondt, A. (2024), Antigen-specific Fab profiling achieves molecular-resolution analysis of human autoantibody repertoires in rheumatoid arthritis, Nature Communications 15(1).
- Ciaffi, J.; Liem, S.I.E.; Cannegieter, S.C.; Ahmed, S.; Hoekstra, E.; Huizinga, T. & Vries-Bouwstra, J. de (2024), Does a history of smoking increase the risk of developing systemic sclerosis? , Rheumatology Advances in Practice 8(2).
- Cope, A.P.; Jasenecova, M.; Vasconcelos, J.C.; Filer, A.; Raza, K.; Qureshi, S.; D'Agostino, M.A.; Mcinnes, I.B.; Isaacs, J.; Pratt, A.G.; Fisher, B.A.; Buckley, C.; Emery, P.; Ho, P.L.E.; Buch, M.H.; Ciurtin, C.; Schaardenburg, D. van; Huizinga, T.; Toes, R.; Georgiou, E.; Kelly, J.; Murphy, C.; Prevost, A.T. & APIPPRA study investigators (2024), Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA), The Lancet 403(10429): 838-849.
- Volkov, M.; Kampstra, A.S.B.; Schie, K.A.J. van; Mourik, A.G. van; Kwekkeboom, J.C.; Ru, A. de; Veelen, P.A. van; Huizinga, T.W.J.; Toes, R.E.M. & Woude, D. van der (2024), Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response, RMD Open: Rheumatic and Musculoskeletal Diseases 10(3).
- Neppelenbroek, S.; Blomberg, N.J.; Kampstra, A.S.B.; Hem, J.G.K. van der; Huizinga, T.W.J. & Scherer, H.U. (2024), Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis, Journal of Autoimmunity 149.
- Marges, E.R.; Sar, I.G. van der; Vries-Bouwstra, J.K. de; Huizinga, T.W.J.; Daele, P.L.A. van; Wijsenbeek, M.S.; Moor, C.C. & Geelhoed, J.J.M. (2024), Detection of Systemic Sclerosis-associated Interstitial Lung Disease by Exhaled Breath Analysis Using Electronic Nose Technology, American Journal of Respiratory and Critical Care Medicine 210(4): 512-514.
- Huizinga, T.W.J.; Dipasquale, V.; Zabransky, M.; Heyn, J. & Romano, C. (2024), Infliximab biosimilar GP1111: a review of 5 years' post-approval experience, Expert Opinion on Biological Therapy 24(7): 615-625.
- Taylor, P.C.; Schett, G.; Huizinga, T.W.; Wang, Q.M.; Ibrahim, F.; Zhou, B.; Liva, S.G.; Shaik, J.S.B.; Xiong, Y.; Leu, J.H.; Panchakshari, R.A.; Loza, M.J.; Ma, K.Y.; Dhatt, H.; Cella, R.R.; Karyekar, C.S.; Cuff, C.A.; Gao, S. & Fei, K.Y. (2024), Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy, RMD Open: Rheumatic and Musculoskeletal Diseases 10(2).
- Pol, J.A. van der; Allaart, C.F.; Huizinga, T.W.J. & Bergstra, S.A. (2024), Are poor prognostic factors a realistic basis for treatment decisions in patients with rheumatoid arthritis? Lessons from the IMPROVED study, RMD Open: Rheumatic and Musculoskeletal Diseases 10(2).
- Heckert, S.L.; Maassen, J.M.; Nevins, I.; Baudoin, P.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Bergstra, S.A. & Allaart, C.F. (2024), Long-term clinical outcomes in early rheumatoid arthritis that was treated-to-target in the BeSt and IMPROVED studies, Rheumatology.
- Oostveen, W.M. van; Huizinga, T.W.J. & Fehres, C.M. (2024), Pathogenic role of anti-nuclear autoantibodies in systemic sclerosis, Immunological Reviews.
- Arriens, C.; Teng, Y.K.O.; Ginzler, E.M.; Parikh, S.V.; Askanase, A.D.; Saxena, A.; Gibson, K.; Caster, D.J.; Atsumi, T.; Lisk, L.; Randhawa, S.; Gluck, R.; Solomons, N. & Huizinga, R.B. (2023), Update on the efficacy and safety profile of voclosporin, Arthritis Care & Research.
- Heckert, S.L.; Hissink-Muller, P.C.E.; Berg, J.M. van den; Schonenberg-Meinema, D.; Suijlekom-Smit, L.W.A. van; Rossum, M.A.J. van; Koopman, Y.; Cate, R. ten; Brinkman, D.M.C.; Huizinga, T.W.J.; Allaart, C.F. & Bergstra, S.A. (2023), Patterns of clinical joint inflammation in juvenile idiopathic arthritis, RMD Open 9(1).
- Emery, P.; Tanaka, Y.; Bykerk, V.P.; Huizinga, T.W.J.; Citera, G.; Bingham, C.O.; Banerjee, S.; Soule, B.P.; Nys, M.; Connolly, S.E.; Lozenski, K.L.; Zhuo, J.; Wong, R.; Huang, K.H.G. & Fleischmann, R. (2023), Sustained remission and outcomes with abatacept plus methotrexate following stepwise dose de-escalation in patients with early rheumatoid arthritis, Rheumatology and Therapy 10(3): 707-727.
- Ciaffi, J.; Liem, S.I.E.; Leeuwen, N.M. van; Allaart, C.F.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2023), Comment on, Rheumatology.
- Holborough-Kerkvliet, M.D.; Mucignato, G.; Moons, S.J.; Psomiadou, V.; Konada, R.S.R.; Pedowitz, N.J.; Pratt, M.R.; Kissel, T.; Koeleman, C.A.M.; Tjokrodirijo, R.T.N.; Veelen, P.A. van; Huizinga, T.; Schie, K.A.J. van; Wuhrer, M.; Kohler, J.J.; Bonger, K.M.; Boltje, T.J. & Toes, R.E.M. (2023), A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners, Glycobiology 33(9): 732-744.
- Winchow, L.L.; Tikly, M.; Musenge, E.; Chopra, A.; Huizinga, T.W.J.; Salomon-Escoto, K.; Tavares-Costa, J. & Govind, N. (2023), Changes in physical function using three methods of scoring the Health Assessment Questionnaire in established active rheumatoid arthritis, Indian Journal of Rheumatology 18(SUPPL 1): S76-+.
- Heckert, S.L.; Maassen, J.M.; Cessie, S. le; Goekoop-Ruiterman, Y.P.M.; Güler-Yüksel, M.; Lems, W.; Huizinga, T.W.; Bergstra, S.A. & Allaart, C.F. (2023), Long-term mortality in treated-to-target RA and UA, Annals of the Rheumatic Diseases 83.
- Monahan, R.C.; Voorde, L.J.J. van de; Fronczek, R.; Bresser, J. de; Eikenboom, J.; Kloppenburg, M.; Middelkoop, H.A.M.; Terwindt, G.M.; Wee, N.J.A. van der; Huizinga, T.W.J. & Steup-Beekman, G.M. (2023), Clinical outcome in patients with suspected inflammatory neuropsychiatric lupus treated with immunosuppression, Lupus Science & Medicine 10(1).
- Nevins, I.; Allaart, C.; Vega-Morales, D.; Winchow, L.L.; Chopra, A.; Rodrigues, A.M.; Huizinga, T.; Boers, M. & Bergstra, S.A. (2023), THE RATIO BETWEEN BIOLOGICAL AND GLUCOCORTICOID USE IN VARIOUS COUNTRIES WORLDWIDE: RESULTS FROM THE METEOR REGISTRY, Annals of the Rheumatic Diseases 82: 552-553.
- Beukel, M.D. van den; Wesemael, T.J. van; Hoogslag, A.T.W.; Borggreven, N.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Toes, R.E.M.; Woude, D. van der & Trouw, L.A. (2023), Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association, RMD Open 9(4).
- Maurits, M.P.; Wouters, F.; Niemantsverdriet, E.; Huizinga, T.W.J.; Akker, E.B. van den; Cessie, S. le; Mil, A.H.M.V. & Knevel, R. (2023), The role of genetics in clinically suspect arthralgia and rheumatoid arthritis development, Arthritis & Rheumatology 75(2): 178-186.
- Ciaffi, J.; Ruscitti, P.; Cola, I. di; Pavlych, V.; Italiano, N.; Gentile, M.; Huizinga, T.; Vries-Bouwstra, J.K. de; Ursini, F. & Cipriani, P. (2023), Whole body insulin sensitivity is increased in systemic sclerosis, PLoS ONE 18(3).
- Liem, S.I.E.; Hoekstra, E.M.; Bonte-Mineur, F.; Checa, C.M.; Schouffoer, A.; Allaart, C.F.; Huizinga, T.W.J.; Bergstra, S.A. & Vries-Bouwstra, J.K. de (2023), The effect of silver fibre gloves on Raynaud's phenomenon in patients with systemic sclerosis, Rheumatology 62(S1): SI74-SI81.
- Nevins, I.; Courvoisier, D.; Finckh, A.; Fritsch-Stork, R.; Nordström, D.; Rodrigues, A.M.; Dinescu, S.C.; Martos, A.G.; Oztas, M.; Rotar, Z.; Solomon-Escoto, K.; Chopra, A.; Vega-Morales, D.; Buck, P.D. de; Choquette, D.; Conway, R.; Iannone, F.; Allaart, C.; Huizinga, T.; Lauper, K. & Bergstra, S.A. (2023), CROSS COUNTRY DIFFERENCES IN B/TSDMARD PRESCRIPTION BEHAVIOR: ASSOCIATIONS BETWEEN SOCIOECONOMICS, REAL WORLD B/ TSDMARD USE AND DISEASE OUTCOMES, Annals of the Rheumatic Diseases 82: 2035-2036.
- Heckert, S.L.; Muller, P.C.E.H.; Berg, J.M. van den; Schonenberg-Meinema, D.; Suijlekom-Smit, L.W.A. van; Rossum, M. van; Koopman-Keemink, Y.; Cate, R. ten; Brinkman, D.M.C.; Huizinga, T.; Allaart, C. & Bergstra, S.A. (2023), PATTERNS OF CLINICAL JOINT INFLAMMATION IN JUVENILE IDIOPATHIC ARTHRITIS, Annals of the Rheumatic Diseases 82: 107-107.
- Ciaffi, J.; Liem, S.; Leeuwen, N. van; Allaart, C.; Huizinga, T. & Vries-Bouwstra, J. de (2023), TREATMENT TAPERING IN SYSTEMIC SCLEROSIS: A 10-YEAR FOLLOW-UP STUDY, Annals of the Rheumatic Diseases 82: 966-967.
- Winthrop, K.L.; Isaacs, J.D.; Mease, P.J.; Boumpas, D.T.; Baraliakos, X.; Gottenberg, J.E.; Siebert, S.; Mosca, M.; Basu, N.; Orange, D.; Lories, R.; Aletaha, D.; McInnes, I.B.; Huizinga, T.W.J.; Voll, R.E.; Gravallese, E.M.; Breedveld, F.C. & Smolen, J.S. (2023), Unmet need in rheumatology, Annals of the Rheumatic Diseases 82(5).
- Heckert, S.L.; Bergstra, S.A.; Goekoop-Ruiterman, Y.P.M.; Gueler-Yueksel, M.; Lems, W.F.; Matthijssen, X.M.E.; Oosterhout, M. van; Huizinga, T.W.J. & Allaart, C.F. (2023), Frequency of joint inflammation is associated with local joint damage progression in rheumatoid arthritis despite long-term targeted treatment, RMD Open 9(1).
- Liem, S.I.E.; Bergstra, S.A.; Ciaffi, J.; Meulen, C. van der; Ueckert, D.A.; Schriemer, M.R.; Huizinga, T.W.J.; Vlieland, T.P.M.V. & Vries-Bouwstra, J.K. de (2023), The long-term course of the Health Assessment Questionnaire in patients with systemic sclerosis, Journal of Scleroderma and Related Disorders.
- Liem, S.I.E.; Neppelenbroek, S.; Fehres, C.M.; Wevers, B.A.; Toes, R.E.M.; Allaart, C.F.; Huizinga, T.W.J.; Scherer, H.U. & Vries-Bouwstra, J.K. de (2023), Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies, RMD Open 9(1).
- Winthrop, K.L.; Mease, P.; Kerschbaumer, A.; Voll, R.E.; Breedveld, F.C.; Smolen, J.S.; Gottenberg, J.E.; Baraliakos, X.; Kiener, H.P.; Aletaha, D.; Isaacs, J.D.; Buch, M.H.; Crow, M.K.; Kay, J.; Crofford, L.; Vollenhoven, R.F. van; Ospelt, C.; Siebert, S.; Kloppenburg, M.; Mcinnes, I.B.; Huizinga, T.W.J. & Gravallese, E.M. (2023), Unmet need in rheumatology, Annals of the Rheumatic Diseases.
- Ciaffi, J.; Liem, S.; Wiland, P.; Atsumi, T.; Szücs, G.; Pellerito, R.; Balbir-Gurman, A.; Czirják, L.; Zanatta, E.; Koetter, I.; Shah, A.; Henes, J.; Matucci-Cerinic, M.; Airò, P.; Ursini, F.; Huizinga, T. & Vries-Bouwstra, J. de (2023), SMOKING INFLUENCE ON AUTOANTIBODY PROFILE AND DISEASE PROGRESSION IN SYSTEMIC SCLEROSIS: AN EUSTAR DATABASE ANALYSIS, Annals of the Rheumatic Diseases 82: 975-975.
- Ciaffi, J.; Liem, S.; Huizinga, T. & Vries-Bouwstra, J. de (2023), SMOKING DOES NOT REPRESENT A SUSCEPTIBILITY FACTOR FOR THE DEVELOPMENT OF SYSTEMIC SCLEROSIS: AN ANALYSIS OF THE LEIDEN CCISS COHORT, Annals of the Rheumatic Diseases 82: 1660-1661.
- Bitoun, S.; Hässler, S.; Ternant, D.; Szely, N.; Gleizes, A.; Bey, S.H.; Richez, C.; Soubrier, M.; Avouac, J.; Brocq, O.; Sellam, J.; Vries, N. de; Huizinga, T.; Jury, E.; Manson, J.; Mauri, C.; Matucci, A.; Mulleman, D.; Pallardy, M.; Bröet, P. & Mariette, X. (2023), ANTIDRUG ANTIBODIES ARE NEGATIVELY ASSOCIATED WITH RESPONSE TO BIOLOGICAL DRUGS IN PATIENTS WITH RHEUMATOID ARTHRITIS: RESULTS OF THE ABIRISK STUDY, Annals of the Rheumatic Diseases 82: 590-590.
- Cope, A.; Jasenecova, M.; Vasconcelos, J.; Filer, A.; Raza, K.; Qureshi, S.; D'agostino, M.A.; Mcinnes, I.; Isaacs, J.; Pratt, A.; Fisher, B.; Buckley, C.D.; Emery, P.; Ho, P.; Buch, M.H.; Ciurtin, C.; Huizinga, T.; Schaardenburg, D. van; Murphy, C. & Prevost, T. (2023), ABATACEPT IN INDIVIDUALS AT RISK OF DEVELOPING RHEUMATOID ARTHRITIS: RESULTS FROM THE ARTHRITIS PREVENTION IN THE PRECLINICAL PHASE OF RA WITH ABATACEPT (APIPPRA) TRIAL, Annals of the Rheumatic Diseases 82: 86-86.
- Blomberg, N.; Kwekkeboom, J.; Böhringer, S.; Huizinga, T.; Toes, R. & Scherer, H.U. (2023), ABATACEPT TO SILENCE ANTI-CITRULLINATED PROTEIN ANTIBODY-EXPRESSING B CELLS IN RHEUMATOID ARTHRITIS: THE ASCARA TRIAL, Annals of the Rheumatic Diseases 82: 11-11.
- Heckert, S.L.; Maarseveen, T.; Marges, E.R.; Chopra, A.; Vega-Morales, D.; Toit, R. du; Winchow, L.L.; Gutierrez, C.E.T.; Knevel, R.; Helm-van Mil, A. van der; Huizinga, T.; Allaart, C. & Bergstra, S.A. (2023), RHEUMATOID ARTHRITIS ASSOCIATED INTERSTITIAL LUNG DISEASE ACROSS CONTINENTS, Annals of the Rheumatic Diseases 82: 844-845.
- Khidir, S.J.H.; Boonstra, M.; Bergstra, S.A.; Boerrigter, G.W.M.; Voog-van der Harst, E.M.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der & Vries-Bouwstra, J.K. de (2023), Mouth opening in systemic sclerosis, Journal of Scleroderma and Related Disorders 8(1): 64-71.
- D'Onofrio, B.; Helm-van Mil, A. van der; Huizinga, T.W.J. & Mulligen, E. van (2023), Inducibility or predestination? Queries and concepts around drug-free remission in rheumatoid arthritis, Expert Review of Clinical Immunology 19(2): 217-225.
- Liem, S.I.E.; Ciaffi, J.; Leeuwen, N.M. van; Boonstra, M.; Ahmed, S.; Voorde, L.J.J. van de; Corsel, A.; Dhondai, T.; Ninaber, M.K.; Geelhoed-Veltman, J.J.M.; Heuvers, M.E.; Tushuizen, M.E.; Marsan, N.A.; Kies, P.; Schouffoer, A.A.; Huizinga, T.W.J.; Allaart, C.F. & Vries-Bouwstra, J. de (2023), Step forward in early recognition of systemic sclerosis, RMD Open 9(2).
- Pol, J.A. van der; Akdemir, G.; Broek, M. van den; Dirven, L.; Kerstens, P.J.S.M.; Lems, W.F.; Markusse, I.M.; Huizinga, T.W.J. & Allaart, C.F. (2023), Repair of joint damage in patients with rheumatoid arthritis does not relate to previous suppression of inflammation, RMD Open 9(2).
- Ouwerkerk, L. van; Verschueren, P.; Boers, M.; Emery, P.; Jong, P.H.P. de; Landewé, R.B.M.; Lems, W.; Smolen, J.S.; Huizinga, T.W.; Allaart, C.F. & Bergstra, S.A. (2023), Initial glucocorticoid bridging in rheumatoid arthritis, Annals of the Rheumatic Diseases 83.
- Liem, S.I.E.; Neppelenbroek, S.; Fehres, C.M.; Wortel, C.; Toes, R.E.M.; Huizinga, T.W.J.; Scherer, H.U. & Vries-Bouwstra, J.K.D. (2023), Autoreactive B cell responses targeting nuclear antigens in systemic sclerosis, Seminars in Arthritis and Rheumatism 58.
- Wortel, C.M.; Liem, S.I.; Leeuwen, N.M. van; Boonstra, M.; Fehres, C.M.; Stoeger, L.; Huizinga, T.W.; Toes, R.E.M.; Vries-Bouwstra, J. de & Scherer, H.U. (2023), Anti-topoisomerase, but not anti-centromere B cell responses in systemic sclerosis display active, Ig-secreting cells associated with lung fibrosis, RMD Open 9(3).
- Liem, S.I.E.; Hoekstra, E.M.; Levarht, E.W.N.; Dorjee, A.L.; Scherer, H.U.; Toes, R.E.M.; Huizinga, T.W.J.; Vries-Bouwstra, J.K. de & Fehres, C.M. (2023), Anti-carbamylated protein antibodies in systemic sclerosis, Arthritis Research and Therapy 25(1).
- Huizinga, T.; Choy, E.; Praestgaard, A.; Hoogstraten, H. van; LaFontaine, P.R.; Guyot, P.; Aletaha, D.; Müller-Ladner, U.; Tanaka, Y.; Curtis, J.R. & Fleischmann, R. (2023), Clinical efficacy of sarilumab versus upadacitinib over 12 weeks, Rheumatology and Therapy 10(3): 539-550.
- Koers, J.; Sciarrillo, R.; Derksen, N.I.L.; Vletter, E.M.; Fillie-Grijpma, Y.E.; Raveling-Eelsing, E.; Graca, N.A.G.; Leijser, T.; Pas, H.H.; Nijen-Vos, L.L. van; Braham, M.V.J.; Buisman, A.M.; Jong, J. de; Schriek, A.I.; Tio-Gillen, A.P.; Teng, Y.K.O.; Steenhuis, M.; Swaneveld, F.H.; Taeye, S.W. de; Gils, M.J. van; Verschuuren, J.J.G.M.; Rutgers, B.; Heeringa, P.; Horvath, B.; Jacobs, B.C.; Leeuw, K. de; Franssen, C.F.M.; Veyradier, A.; Coppo, P.; Gelderman, K.A.; Ham, D.H.S.M. van; Els, C.A.C.M. van; Woude, D. van der; Huizinga, R.; Huijbers, M.G.; Kuijpers, T.W.; Toes, R.E.M.; Bos, N.A.; Rispens, T. & T2B Consortium (2023), Differences in IgG autoantibody Fab glycosylation across autoimmune diseases, Journal of Allergy and Clinical Immunology 151(6): 1646-1654.
- Moel, E.C. de; Trouw, L.A.; Terao, C.; Govind, N.; Tikly, M.; El-Gabalawy, H.; Smolik, I.; Bang, H.; Huizinga, T.W.J.; Toes, R.E.M. & Woude, D. van der (2023), Geo-epidemiology of autoantibodies in rheumatoid arthritis, Arthritis Research and Therapy 25(1).
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- Monahan, R.; Beukel, M. van; Borggreven, N.; Kloppenburg, M.; Huizinga, T.W.J.; Steup-Beekman, G. & Trouw, L. (2021), Malondialdehyde-acetaldehyde Antibodies Occur in Systemic Lupus Erythematosus and Associate Specifically with Neuropsychiatric Involvement, Arthritis and Rheumatology 73: 3107-3108.
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- Kissel, T.; Wesemael, T.J. van; Lundquist, A.; Kokkonen, H.; Kawakami, A.; Tamai, M.; Schaardenburg, D. van; Wuhrer, M.; Huizinga, T.W.J.; Scherer, H.U.; Woude, D. van der; Rantapaa-Dahlqvist, S. & Toes, R.E.M. (2021), Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA, Annals of the Rheumatic Diseases.
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- Heckert, S.; Bergstra, S.A.; Matthijssen, X.; Goekoop-Ruiterman, Y.; Fodili, F.; Allaart, C. & Huizinga, T. (2021), Joint inflammation tends to recur in the same joints during the rheumatoid arthritis disease course, Annals of the Rheumatic Diseases 80: 259-259.
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- Monahan, R.; Inglese, F.; Middelkoop, H.; Buchem, M. van; Huizinga, T.; Kloppenburg, M.; Ronen, I.; Steup-Beekman, G.M. & Bresser, J. de (2021), White matter hyperintensities lead to reduced psychomotor speed in patients with systemic lupus erythematosus and neuropsychiatric symptoms, Annals of the Rheumatic Diseases 80(Suppl 1): 606-607.
- Monahan, R.; Blonk, A.; Middelkoop, H.; Kloppenburg, M.; Huizinga, T.; Wee, N. van der & Steup-Beekman, G.M. (2021), Psychiatric disorders in patients with different phenotypes of neuropsychiatric systemic lupus erythematosus (NPSLE), Annals of the Rheumatic Diseases 80(Suppl 1): 603-604.
- Monahan, R.; Blonk, A.; Middelkoop, H.; Kloppenburg, M.; Huizinga, T.; Wee, N. van der & Steup-Beekman, G.M. (2021), Lupus fog is not dissociative fog, Annals of the Rheumatic Diseases 80: 604-604.
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- Karakaya, B.; Moorsel, C.H.M. van; Veltkamp, M.; Roodenburg-Benschop, C.; Kazemier, K.M.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Grutters, J.C. & Rijkers, G.T. (2021), A polymorphism in C-C Chemokine Receptor 5 (CCR5) associates with Lofgren's syndrome and alters receptor expression as well as functional response, Cells 10(8).
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- Inglese, F.; Kant, I.M.J.; Monahan, R.C.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Buchem, M.A. van; Magro-Checa, C.; Ronen, I. & Bresser, J. de (2021), Different phenotypes of neuropsychiatric systemic lupus erythematosus are related to a distinct pattern of structural changes on brain MRI, European Radiology 31.
- Monahan, R.C.; Beaart-van de Voorde, L.J.J.; Eikenboom, J.; Fronczek, R.; Kloppenburg, M.; Middelkoop, H.A.M.; Terwindt, G.M.; Wee, N.J.A. van der; Huizinga, T.W.J. & Steup-Beekman, G.M. (2021), Fatigue in patients with systemic lupus erythematosus and neuropsychiatric symptoms is associated with anxiety and depression rather than inflammatory disease activity, Lupus 30(7).
- Slot, L.M.; Vergroesen, R.D.; Kerkman, P.F.; Staudinger, E.; Reijm, S.; Dooren, H.J. van; Voort, E.I.H. van der; Huizinga, T.W.J.; Toes, R.E.M. & Scherer, H.U. (2021), Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis, PLoS ONE 16(3).
- Curtis, J.R.; Weinblatt, M.E.; Shadick, N.A.; Brahe, C.H.; Ostergaard, M.; Hetland, M.L.; Saevarsdottir, S.; Horton, M.; Mabey, B.; Flake, D.D.; Ben-Shachar, R.; Sasso, E.H. & Huizinga, T.W. (2021), Validation of the adjusted multi-biomarker disease activity score as a prognostic test for radiographic progression in rheumatoid arthritis, Arthritis Research and Therapy 23(1).
- Habers, G.E.A.; Helm-van Mil, A.H.M. van der; Veldhuijzen, D.S.; Allaart, C.F.; Vreugdenhil, E.; Starreveld, D.E.J.; Huizinga, T.W.J. & Evers, A.W.M. (2021), Earlier chronotype in patients with rheumatoid arthritis (Jan, 10.1007/s10067-020-05546-x, 2021), Clinical Rheumatology 40: 0-0.
- Habers, G.E.A.; Helm-van Mil, A.H.M. van der; Veldhuijzen, D.S.; Allaart, C.F.; Vreugdenhil, E.; Starreveld, D.E.J.; Huizinga, T.W.J. & Evers, A.W.M. (2021), Earlier chronotype in patients with rheumatoid arthritis, Clinical Rheumatology 40.
- Wind, M.; Hendriks, M.; Brussel, B.T.J. van; Eikenboom, J.; Allaart, C.F.; Lamb, H.J.; Siebelink, H.M.J.; Ninaber, M.K.; Geloven, N. van; Lith, J.M.M. van; Huizinga, T.W.J.; Rabelink, T.J.; Sueters, M. & Teng, Y.K.O. (2021), Effectiveness of a multidisciplinary clinical pathway for women with systemic lupus erythematosus and/or antiphospholipid syndrome, Lupus Science & Medicine 8(1).
- Leeuwen, N.M. van; Ciaffi, J.; Schoones, J.W.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2021), Contribution of sex and autoantibodies to microangiopathy assessed by nailfold videocapillaroscopy in systemic sclerosis, Arthritis Care and Research 73(5).
- Huizinga, T.W.J.; Torii, Y. & Muniz, R. (2020), Adalimumab biosimilars in the treatment of rheumatoid arthritis, Rheumatology and Therapy 8.
- Leeuwen, N.M. van; Boonstra, M.; Huizinga, T.W.J.; Kaptein, A.A. & Vries-Bouwstra, J.K. de (2020), Illness perceptions, risk perceptions and worries in patients with early systemic sclerosis, Musculoskeletal Care 18(2).
- Ciaffi, J.; Leeuwen, N.M. van; Liem, S.I.E.; Ninaber, M.K.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2020), Lung function is associated with minimal EQ-5D changes over time in patients with systemic sclerosis, Clinical Rheumatology 39.
- Maarseveen, T.D.; Meinderink, T.; Reinders, M.J.T.; Knitza, J.; Huizinga, T.W.J.; Kleyer, A.; Simon, D.; Akker, E.B. van den & Knevel, R. (2020), Machine learning electronic health record identification of patients with rheumatoid arthritis, JMIR Medical Informatics 8(11).
- Durez, P.; Hoekema, A.; Huizinga, T.; Gazin, M.; Present, E.; Veelaert, D.; Wigerinck, P. & Westhovens, R. (2020), Treatment innovation for patients, Acta Clinica Belgica 77(1).
- Bijnen, S. van; Vries-Bouwstra, J. de; Ende, C.H. van den; Boonstra, M.; Kroft, L.; Geurts, B.; Snoeren, M.; Schouffoer, A.; Spierings, J.; Laar, J.M. van; Huizinga, T.W.J.; Voskuyl, A.; Marijt, E.; Velden, W. van der; Hoogen, F.H.J. van den & Vonk, M.C. (2020), Predictive factors for treatment-related mortality and major adverse events after autologous haematopoietic stem cell transplantation for systemic sclerosis: results of a long-term follow-up multicentre study, Annals of the Rheumatic Diseases 79(8): 1084-1089.
- Huizinga, T.W.J. & Knevel, R. (2020), Interpreting big-data analysis of retrospective observational data, The Lancet Rheumatology 2(11): E652-E653.
- Matthijssen, X.M.E.; Niemantsverdriet, E.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2020), Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and -negative rheumatoid arthritis patients over 25 years, PLoS Medicine 17(9).
- Matthijssen, X.M.E.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2020), Increasing incidence of autoantibody-negative RA is replicated and is partly explained by an aging population, Annals of the Rheumatic Diseases 81(5).
- Matthijssen, X.M.E.; Huizinga, T.W.J.; Niemantsverdriet, E. & Helm-van Mil, A.H.M. van der (2020), Early intensive treatment normalises excess mortality in ACPA-negative RA but not in ACPA-positive RA.
- Kay, J.; Harigai, M.; Rancourt, J.; Dickson, C.; Melby, T.; Issa, M.; Torre, I. de la; Isaka, Y.; Cardoso, A.; Saifan, C.; Keystone, E.C.; Vollenhoven, R.F. van; Giles, J.T.; Huizinga, T.W.J. & Kremer, J.M. (2020), Changes in selected haematological parameters associated with JAK1/JAK2 inhibition observed in patients with rheumatoid arthritis treated with baricitinib, RMD Open 6(3).
- Boonstra, M.; Bakker, J.A.; Grummels, A.; Ninaber, M.K.; Marsan, N.A.; Wortel, C.M.; Huizinga, T.W.J.; Jordan, S.; Hoffman-Vold, A.M.; Distler, O.; Toes, R.E.M.; Scherer, H.U. & Vries-Bouwstra, J.K. de (2020), Association of anti-topoisomerase I antibodies of the IgM isotype with disease progression in anti-topoisomerase I-positive systemic sclerosis, Arthritis and Rheumatology 72(11): 1897-1904.
- Dijk, B.T. van; Trouw, L.A.; Helm-van Mil, A.H.M. van der & Huizinga, T.W.J. (2020), Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al., Arthritis Research and Therapy 22.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.; Terwindt, G.; Wee, N. van der; Rosendaal, F.; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, M. (2020), Mortality in patients with systemic lupus erythematosus and neuropsychiatric involvement: A retrospective analysis from a tertiary referral center in the Netherlands, Lupus 29(14): 1892-1901.
- Dos-Santos, R.; Bergstra, S.A.; Maassen, J.M.; Huizinga, T. & Allaart, C.F. (2020), Is It Realistic to Stop Prednisone in Early Rheumatoid Arthritis? A Subanalysis from the BeSt and IMPROVED Studies, Arthritis and Rheumatology 72.
- Monahan, R.C.; Beaart, H.J.L.; Fronczek, R.; Terwindt, G.M.; Beaart-van de Voorde, L.J.J.; Bresser, J. de; Kloppenburg, M.; Wee, N.J.A. van der; Huizinga, T.W.J. & Steup-Beekman, G.M. (2020), Suspected transverse myelitis with normal MRI and CSF findings in a patient with Lupus: what to do? A case series and systematic review, Neuropsychiatric Disease and Treatment 16: 3173-3186.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.J.J.; Terwindt, G.; Wee, N. van der; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, G.M. (2020), Extreme fatigue in patients with systemic Lupus erythematosus and neuropsychiatric symptoms , Annals of the Rheumatic Diseases 79: 1487-1488.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.; Terwindt, G.; Wee, N. van der; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, M. (2020), Extreme Fatigue in Patients with Systemic Lupus Erythematosus and Neuropsychiatric Symptoms, Arthritis and Rheumatology 72.
- Wesemael, T. van; Salioska, N.; Dorjee, A.; Huizinga, T.; Helm-van Mil, A. van der; Toes, R. & Woude, D. van der (2020), Anti-acetylated Protein Antibodies in Rheumatoid Arthritis (RA): Clues for the Starting Point of Autoantibody Responses in RA, Arthritis and Rheumatology 72.
- Emery, P.; Tanaka, Y.; Bykerk, V.; Bingham, C.; Huizinga, T.; Citera, G.; Huang, K.H.G.; Connolly, S.; Elbez, Y.; Wong, R.; Lozenski, K. & Fleischmann, R. (2020), Clinical Responses and Patient Flow over 2 Years of Treatment with Abatacept, Including Dose De-Escalation, in Patients with Early, MTX-Naive, ACPA plus RA: Results from a Phase IIIb Study, Arthritis and Rheumatology 72.
- Leeuwen, N. van; Ciaffi, J.; Liem, S.; Huizinga, T. & Vries-Bouwstra, J. de (2020), Determinants of Health-related Quality of Life in Systemic Sclerosis, Arthritis and Rheumatology 72.
- Leeuwen, N. van; Maurits, M.; Liem, S.; Ciaffi, J.; Marsan, N.A.; Ninaber, M.; Huizinga, T. & Vries-Bouwstra, J. de (2020), Machine Learning Assisted Prediction of Progression in Systemic Sclerosis Patients: An Approach to Concise, Tailored Model Construction Using Outpatient Clinical Data, Arthritis and Rheumatology 72.
- Kissel, T.; Ge, C.R.; Hafkenscheid, L.; Slot, L.; Cavallari, M.; Kwekkeboom, J.; Wuhrer, M.; Huizinga, T.; Scherer, H.; Reth, M.; Holmdahl, R. & Toes, R. (2020), N-linked Glycosylation of the Immunoglobulin Variable Domain Affects Antigen Binding and Autoreactive B Cell Activation, Arthritis and Rheumatology 72.
- Burmester, G.; Bykerk, V.; Buch, M.; Tanaka, Y.; Kameda, H.; Praestgaard, A.; Hoogstraten, H. van; Fernandez-Nebro, A. & Huizinga, T. (2020), Similar Efficacy of Sarilumab Monotherapy (MONARCH) vs Sarilumab and Methotrexate Combination Therapy (MOBILITY B) in Patients with Rheumatoid Arthritis, Arthritis and Rheumatology 72.
- Dijk, B.T. van; Trouw, L.A.; Helm-van Mil, A.H.M. van der & Huizinga, T.W.J. (2020), Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al.
- Gegenava, T.; Gegenava, M.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Bax, J.J.; Delgado, V. & Marsan, N.A. (2020), Left ventricular systolic function in patients with systemic lupus erythematosus and its association with cardiovascular events, Journal of The American Society of Echocardiography 33(9): 1116-1122.
- Knevel, R.; Cessie, S. le; Terao, C.C.; Slowikowski, K.; Cui, J.; Huizinga, T.W.J.; Costenbader, K.H.; Liao, K.P.; Karlson, E.W. & Raychaudhuri, S. (2020), Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis, Science Translational Medicine 12(545).
- Huizinga, T.; Weinblatt, M.E.; Shadick, N.; Brahe, C.H.; Ostergaard, M.; Hetland, M.L.; Saevarsdottir, S.; Horton, M.; Mabey, B.; Flake, D.; Ben-Shachar, R.; Sasso, E.; Gutin, A.; Hitraya, E.; Lanchbury, J. & Curtis, J. (2020), Training and validation of a multivariate predictor of risk of radiographic progression for patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 79: 1909-1909.
- Ciaffi, J.; Leeuwen, N.M. van; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2020), Smoking and systemic sclerosis: influence on microangiopathy and expression of anti-topoisomerase I antibodies in a monocentric cohort, Clinical and Experimental Rheumatology 38(3): S25-S28.
- Ciaffi, J.; Leeuwen, N.M. van; Schoones, J.W.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2020), Sex hormones and sex hormone-targeting therapies in systemic sclerosis: a systematic literature review, Seminars in Arthritis and Rheumatism 50(1): 140-148.
- Manai, M.; Middendorp, H. van; Veldhuijzen, D.S.; Pol, J.A. van der; Huizinga, T.W.J. & Evers, A.W.M. (2020), Pharmacological conditioning in the treatment of recent-onset rheumatoid arthritis, Trials 21(1).
- Silvagni, E.; Giollo, A.; Sakellariou, G.; Ughi, N.; D'Amico, M.E.; Scire, C.A. & Huizinga, T.W.J. (2020), One year in review 2020: novelties in the treatment of rheumatoid arthritis, Clinical and Experimental Rheumatology 38(2): 181-194.
- Emery, P.; Tanaka, Y.; Bykerk, V.; Huizinga, T.; Citera, G.; Bingham, C.; Banerjee, S.; Connolly, S.; Zhuo, J.; Wong, R.; Huang, K.H.G.; Lozenski, K.; Elbez, Y. & Fleischmann, R. (2020), Maintenance of SDAI remission and patient-reported outcomes (PROS) following dose de-escalation of abatacept in MTX-naive, anti-citrullinated protein antibody (ACPa) plus patients with early Ra: results from avert-2, a randomised phase IIIB study, Annals of the Rheumatic Diseases 79: 981-982.
- Emery, P.; Tanaka, Y.; Bykerk, V.; Bingham, C.; Huizinga, T.; Citera, G.; Huang, K.H.G.; Connolly, S.; Elbez, Y.; Wong, R.; Lozenski, K. & Fleischmann, R. (2020), Maintenance of clinical response with abatacept in combination with MTX in individual patients with early Ra who are MTX-naive and anti-citrullinated protein antibody (ACPA) plus : results from the induction period of avert-2, a randomised phase IIIB study, Annals of the Rheumatic Diseases 79: 619-619.
- Pachai, C.; Connolly, S.; Landis, J.; Tanaka, Y.; Bykerk, V.; Huizinga, T.; Citera, G.; Bingham, C.; Wong, R.; Huang, K.H.G.; , S. du; Hayes, W.; Wu, C.; Fleischmann, R. & Emery, P. (2020), IMPACT OF BASELINE EROSION SCORE ON RESPONSE TO TREATMENT AND FUTURE RADIOLOGICAL DAMAGE IN AVERT-2, A RANDOMISED PHASE IIIB STUDY OF ABATACEPT IN MTX-NAIVE, ANTI-CITRULLINATED PROTEIN ANTIBODY-POSITIVE (ACPA plus ) PATIENTS WITH EARLY RA, Annals of the Rheumatic Diseases 79: 257-257.
- Maurits, M.; Huizinga, T.; Reinders, M.; Raychaudhuri, S.; Karlson, E.; Akker, E. van den & Knevel, R. (2020), High-throughput methodology for EMR-based identification of clinical sub-phenotypes in complex patient populations, Annals of the Rheumatic Diseases 79: 893-893.
- Maarseveen, T.; Maurits, M.; Niemantsverdriet, E.; Huizinga, T.; Helm-van Mil, A. van der & Knevel, R. (2020), Handwork vs machine: a comparison of rheumatoid arthritis patient populations as identified by machine-learning and criteria-based chart review, Annals of the Rheumatic Diseases 79: 1842-1843.
- Moel, E.C. de; Derksen, V.; Trouw, L.A.; Terao, C.; Tikly, M.; El-Gabalawy, H.; Bang, H.; Huizinga, T.; Toes, R. & Woude, D. van der (2020), Geo-epidemiology of autoantibobies in Ra: different prevalences in four ethnically diverse Ra populations , Annals of the Rheumatic Diseases 79: 1247-1248.
- Leeuwen, N. van; Fretheim, H.; Molberg, O.; Huizinga, T.; Vries-Bouwstra, J. de & Hoffmann-Vold, A.M. (2020), Effect of immunosuppressive medication on gastro-intestinal involvement in systemic sclerosis patients stratified for disease duration, Annals of the Rheumatic Diseases 79: 389-390.
- Bergstra, S.A.; VanDer Pol, J.A.; Riyazi, N.; Goekoop-Ruiterman, Y.P.M.; Kerstens, P.J.S.M.; Lems, W.; Huizinga, T.W.J. & Allaart, C.F. (2020), Earlier is better when treating rheumatoid arthritis, RMD Open 6(1).
- Huizinga, T.W.J.; Holers, V.M.; Anolik, J.; Brenner, M.B.; Buckley, C.D.; Bykerk, V.; Connolly, S.E.; Deane, K.D.; Guo, J.P.; Hodge, M.; Hoffmann, S.; Nestle, F.; Pitzalis, C.; Raychaudhuri, S.; Yamamoto, K.; Li, Z.G. & Klareskog, L. (2020), Disruptive innovation in rheumatology, Annals of the Rheumatic Diseases 79(5).
- Wortel, C.; Leeuwen, N. van; Boonstra, M.; Toes, R.; Huizinga, T.; Vries-Bouwstra, J. de & Scherer, H.U. (2020), Differential phenotypes of disease-specific auto-reactive B cell responses in patients with systemic sclerosis , Annals of the Rheumatic Diseases 79: 1089-1090.
- Bergstra, S.A.; Allaart, C.F.; Vega-Morales, D.; Buck, M. de; Murphy, E.; Escoto, K.S. & Huizinga, T.W.J. (2020), Body mass index and treatment survival in patients with RA starting treatment with TNF alpha-inhibitors, RMD Open 6(2).
- Bergstra, S.A.; Vega-Morales, D.; Murphy, E.; Buck, M. de; Solomon-Escoto, K.; Huizinga, T. & Allaart, C. (2020), BMI and treatment survival in ra patients starting treatment with TNF- a-inhibitors: long term follow-up in the real life meteor registry , Annals of the Rheumatic Diseases 79: 978-979.
- Genovese, M.C.; Burmester, G.R.; Gossec, L.; Hoogstraten, H. van; Praestgaard, A.; St John, G.; Huizinga, T.; Aletaha, D. & Fleischmann, R. (2020), ASSOCIATIONS BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND PATIENT-REPORTED OUTCOMES IN SARILUMAB CLINICAL TRIALS, Annals of the Rheumatic Diseases 79: 295-296.
- Kawashiri, S.Y.; Endo, Y.; Nishino, A.; Shimizu, T.; Ueki, Y.; Eiraku, N.; Okada, A.; Matsuoka, N.; Yoshitama, T.; Nakamura, H.; Tamai, M.; Origuchi, T.; Toes, R.; Huizinga, T. & Kawakami, A. (2020), Association between the serologic status of isotype-specific autoantibodies and therapeutic efficacy in rheumatoid arthritis patients treated with abatacept: a prospective ultrasound cohort study in Japan, Annals of the Rheumatic Diseases 79: 624-624.
- Leeuwen, N. van; Bakker, J.; Grummels, A.; Wortel, C.; Jordan, S.; Liem, S.; Distler, O.; Hoffmann-Vold, A.M.; Melsens, K.; Smith, V.; Truchetet, M.E.; Scherer, H.U.; Toes, R.; Huizinga, T. & Vries-Bouwstra, J. de (2020), Anti-centromere antibody isotype levels as biomarker for disease progression in subjects at risk to develop systemic sclerosis, Annals of the Rheumatic Diseases 79: 1096-1096.
- Kissel, T.; Reijm, S.; Slot, L.M.; Cavallari, M.; Wortel, C.M.; Vergroesen, R.D.; Stoeken-Rijsbergen, G.; Kwekkeboom, J.C.; Kampstra, A.S.B.; Levarht, E.W.N.; Drijfhout, J.W.; Bang, H.; Bonger, K.M.; Janssen, G.M.C.; Veelen, P.A. van; Huizinga, T.W.J.; Scherer, H.U.; Reth, M. & Toes, R.E.M. (2020), Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications, Annals of the Rheumatic Diseases 79(4): 472-480.
- Delft, M.A.M. van & Huizinga, T.W.J. (2020), An overview of autoantibodies in rheumatoid arthritis, Journal of Autoimmunity 110.
- Kristyanto, H.; Blomberg, N.J.; Slot, L.M.; Voort, E.I.H. van der; Kerkman, P.F.; Bakker, A.; Burgers, L.E.; Brinck, R.M. ten; Helm-van Mil, A.H.M. van der; Spits, H.; Baeten, D.L.; Huizinga, T.W.J.; Toes, R.E.M. & Scherer, H.U. (2020), Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis, Science Translational Medicine 12(570).
- Monahan, R.C.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.A.M.; Beaart-van de Voorde, L.J.J.; Terwindt, G.M.; Wee, N.J.A. van der; Rosendaal, F.R.; Huizinga, T.W.J.; Kloppenburg, M. & Steup-Beekman, G.M. (2020), Mortality in patients with systemic lupus erythematosus and neuropsychiatric involvement: A retrospective analysis from a tertiary referral center in the Netherlands, Lupus 29(14): 1892-1901.
- Hassler, S.; Bachelet, D.; Duhaze, J.; Szely, N.; Gleizes, A.; Abina, S.H.B.; Aktas, O.; Auer, M.; Avouac, J.; Birchler, M.; Bouhnik, Y.; Brocq, O.; Buck-Martin, D.; Cadiot, G.; Carbonnel, F.; Chowers, Y.; Comabella, M.; Derfuss, T.; Vries, N. de; Donnellan, N.; Doukani, A.; Guger, M.; Hartung, H.P.; Havrdova, E.K.; Hemmer, B.; Huizinga, T.; Ingenhoven, K.; Hyldgaard-Jensen, P.E.; Jury, E.C.; Khalil, M.; Kieseier, B.; Lauren, A.; Lindberg, R.; Loercher, A.; Maggi, E.; Manson, J.; Mauri, C.; Oumoussa, B.M.; Montalban, X.; Nachury, M.; Nytrova, P.; Richez, C.; Ryner, M.; Sellebjerg, F.; Sievers, C.; Sikkema, D.; Soubrier, M.; Tourdot, S.; Trang, C.; Vultaggio, A.; Warnke, C.; Spindeldreher, S.; Donnes, P.; Hickling, T.P.; Mery, A.H.; Allez, M.; Deisenhammer, F.; Fogdell-Hahn, A.; Mariette, X.; Pallardy, M.; Broet, P. & ABIRISK Consortium (2020), Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease, PLoS Medicine 17(10).
- Brouwers, H.; Jonasdottir, H.S.; Kuipers, M.E.; Kwekkeboom, J.C.; Auger, J.L.; Gonzalez-Torres, M.; Lopez-Vicario, C.; Claria, J.; Freysdottir, J.; Hardardottir, I.; Garrido-Mesa, J.; Norling, L.V.; Perretti, M.; Huizinga, T.W.J.; Kloppenburg, M.; Toes, R.E.M.; Binstadt, B.; Giera, M. & Ioan-Facsinay, A. (2020), Anti-inflammatory and proresolving effects of the omega-6 polyunsaturated fatty acid adrenic acid, Journal of Immunology 205(10): 2840-2849.
- Beenakker, K.G.M.; Westendorp, R.G.J.; Craen, A.J.M. de; Chen, S.J.; Raz, Y.; Ballieux, B.E.P.B.; Nelissen, R.G.H.H.; Later, A.F.L.; Huizinga, T.W.; Slagboom, P.E.; Boomsma, D.I. & Maier, A.B. (2020), Men have a stronger monocyte-derived cytokine production response upon stimulation with the gram-negative stimulus lipopolysaccharide than women, Journal of Innate Immunity 12(2): 142-153.
- Kraaij, T.; Arends, E.J.; Dam, L.S. van; Kamerling, S.W.A.; Daele, P.L.A. van; Bredewold, O.W.; Ray, A.; Bakker, J.A.; Scherer, H.U.; Huizinga, T.J.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2020), Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus: 2-year results, Nephrology Dialysis Transplantation 36(8).
- Knevel, R. & Huizinga, T.W.J. (2020), On using machine learning algorithms to define clinically meaningful patient subgroups.
- Gegenava T, Gegenava M, Steup-Beekman M, Huizinga T, Bax J, Delgado V & Ajmone-Marsan N (2019), Assessment of left atrial function in patients with systemic lupus erythematosus with and without neuropsychiatric manifestations: association with cardiovascular events, European Heart Journal 40: 2669-2669.
- van Leeuwen N, Bakker J, Grummels A, Wortel C, Jordan S, Distler O, Fretheim H, Mann-Vold AMH, Scherer HU, Toes R, Huizinga T & de Vries-Bouwstra J (2019), Anticentromere Antibody Levels and Isotypes Associate with Disease Severity in Systemic Sclerosis, Arthritis and Rheumatology 71.
- Winchow LL, Govind N, Musenge E, Chopra A, Huizinga T & Tikly M (2019), A Comparison of Convergent Validity and Sensitivity to Change of the Conventional Scoring Method to Alternative Scoring Methods of the Health Assessment Questionnaire in Rheumatoid Arthritis, Arthritis and Rheumatology 71.
- Mo, Y.Q.; Yang, Z.H.; Wang, J.W.; Li, Q.H.; , X.Y. du; Huizinga, T.W.; Matthijssen, X.M.E.; Shi, G.Z.; Shen, J. & Dai, L. (2019), The value of MRI examination on bilateral hands including proximal interphalangeal joints for disease assessment in patients with early rheumatoid arthritis: a cross-sectional cohort study, Arthritis Research and Therapy 21(1).
- Matthijssen XME, Niemantsverdriet E, Huizinga T & van der Helm-van Mil A (2019), Advances in Treatment of Rheumatoid Arthritis: ACPA-positive Patients Benefited More Than ACPA-negative Patients; 25 Year Results of a Longitudinal Cohort Study, Arthritis and Rheumatology 71.
- Moel, E.C. de; Rech, J.; Mahler, M.; Roth, J.; Vogl, T.; Schouffoer, A.; Goekoop, R.J.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M.; Schett, G. & Woude, D. van der (2019), Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs, Arthritis Research and Therapy 21(1).
- de Moel E, Teeuwisse W, Huizinga T, Toes R, Webb A & van der Woude D (2019), Increased Sodium Accumulation Detected by(23)Na-Magnetic Resonance Imaging in Inflamed Knees of Patients with Autoimmune Joint Disease, Arthritis and Rheumatology 71.
- Maurits M.P., Yuminaga H, Huizinga T.W.J & Knevel R (2019), Mobile health applications in rheumatology: Could they improve our care and research?, International Journal of Clinical Rheumatology.
- Gonzalez-Alvaro, I.; Castrejon, I.; Carmona, L.; Dougados, M.; Huizinga, T.; Abu Shakra, M.; Alberts, A.; Lopez, M.A.; Amital, H.; Aringer, M.; Aslanidis, S.; Berenbaum, F.; Bijlsma, H.; Garcia, F.J.B.; Bliddal, H.; Borofsky, M.; Brocq, O.; Buldakov, S.; Cantini, F.; Perez, L.C.; Chahade, W.; Ciconelli, R.; Codreanu, C.; Dahlqvist, S.R.; Damjanov, N.; Diamantopoulos, A.; Dimdina, L.; Dimic, A.; Dorokhov, A.; Dubikov, A.; Fadienko, G.; Fano, N.; Ferreira, G.; Gabrielli, A.; Gaffney, K.; Gaudin, P.; Gerlag, D.M.; Gerli, R.; Goncalves, C.R.; Hansen, M.S.; Hanvivadhanakul, P.; Hoili, C.; Hou, A.; Hunter, J.; Ilic, T.; Ionescu, R.; Kaine, J.; Kakurina, N.; Kamalova, R.; Kelly, T.; Knyazeva, L.; Krumina, L.; Kurthen, R.; Lagrone, R.P.; Lapadula, G.; Lavrentjevs, V.; Lawson, J.G.; Lazic, Z.; Lejnieks, A.; Levy, Y.; Lexberg, A.; Mader, R.; Mariette, X.; Markovits, D.; Mola, E.M.; Maugars, Y.; Guarch, J.M.; Mazurov, V.I.; Mikkelsen, K.; Vergles, J.M.; Nabizadeh, S.; Nanagara, R.; Nasonov, E.L.; Sarabia, F.N.; Neumann, T.; Novak, S.; Olech, E.; Oza, M.; Paran, D.; Parsik, E.; Pegram, S.; Suarez, M.P.; Popova, T.; Puechal, X.; Raja, N.; Ridley, D.; Rosner, I.; Rubbert-Roth, A.; Rudin, A.; Saraux, A.; Saulite-Kandevica, D.; Settas, L.; Sfikakis, P.; Sheeran, T.; Sizikov, A.; Stamenkovic, D.; Stefanovic, D.; Stolow, J.B.; Tan, A.L.; Tebib, J.; Tishler, M.; Tony, H.P.; Troum, O.M.; Uaratanawong, S.; Angulo, E.U.; Valenzuela, G.; Laken, K. van der; Laar, J. van; Riel, P.L.C.M. van; Vasilopoulos, D.; Veldi, T.; Vinogradova, I.; Vosse, D.; Wassenberg, S.; Weidmann, C.; Weitz, M.; Wollenhaupt, J.; Xavier, R.; Yakupova, S.; Zagar, I.; Zavgorodnaja, T.; Zemerova, E.; Zisman, D.; Zonova, E.; Camona, L.; Alcazar, L.A.; Miguel, C.A. de; Sanchez, J.L.A.; Diez, A.A.; Criado, A.B.; Gualda, E.B.; Serrano, M.A.B.; Audera, J.B.; Fabregat, J.B.; Hernan, G.B.; Fernandez, N.C.; Casado, E.; Mendez, L.C.; Coro, M.C.; Diaz, J.L.C.; Cuesta, E.; Areste, J.F.; Gonzalez, M.F.; Izquierdo, M.G.; Meijide, J.A.G.; Gomez, M.C.G.; Ubeda, E.G.; Centeno, E.G.; Vaquero, C.G.; Fernandez, M.J.G.; Gomez, M.L.G.; Hernandez, T.G.; Gonzalez-Alvaro, I.; Gomez, C.G.M.; Delgado, Y.G.; Masmitja, J.G.; Rio, A.H. del; Instxaurbe, A.R.; Oyarzabal, M.V.I.; Palop, J.; Mas, A.J.; Navarro, E.J.; Padro, M.L.; Longo, F.J.L.; Santamaria, E.L.; Manzano, J.M.; Ruiz, F.J.M.; Bernardo, I.M.; Gonzalez, L.M.; Mazzucheli, R.; San Idelfonso, M.M.; Hernandez, A.N.; Espanol, A.P.; Callizo, E.P.; Donate, J.Q.; Lopez, P.R.; Redondo, J.R.; Gomez, M.R.; Lopez, M.R.; Pardo, R.R.; Alvarez, J.S.; Sala, R.S.; Rey, J.S.R.; Marsa, X.T.; Martin, M.T.; Martin, M.C.T.; Garnica, I.U.; Diego, J.P.V. de; Valls, M.; Garcia, V.V.; Montejo, P.Z.; Tabernero, J.Z.; Balsa, A.; Sanmarti, R.; Cabezas, J.A.; Cantalejo, M.; Chamizo, E.; Ciruelo, E.; Corrales, A.; Cruz, A.; Diaz, C.; Fiter, J.; Freire, M.M.; Galindo, M.; Vicuna, M.R.G. de; Gelman, S.M.; Crespo, R.G.; Fernandez, C.G.; Fernandez, M.J.G.; Hernandez, T.G.; Gracia, A.; Granados, J.; Guzman, M.A.; Irigoyen, M.V.; Juan, A.; Juanola, X.; Laiz, A.; Manero, F.J.; Martinez, A.; Martinez, F.; Mata, C.; Maymo, J.; Navarro, F.J.; Peiro, E.; Perez, F.; Perez, G.; Perez, M.; Pujol, M.; Quiros, J.; Ribas, B.; Riera, M.; Rivera, J.; Rodriguez, J.M.; Gomez, M.R.; Rosello, R.; Tenorio, M.; Toyos, F.J.; ACT-RAY Study Grp; PROAR Study Grp & EMECAR Study Grp (2019), The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity, PLoS ONE 14(4).
- Wijngaarden, S.E. van; Said-Bouyeri, S. ben; Ninaber, M.K.; Huizinga, T.W.J.; Schalij, M.J.; Bax, J.J.; Delgado, V.; Vries-Bouwstra, J.K. de & Marsan, N.A. (2019), Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study, Journal of Rheumatology 46(4): 405-415.
- Curtis, J.R.; Brahe, C.H.; Ostergaard, M.; Hetland, M.L.; Hambardzumyan, K.; Saevarsdottir, S.; Wang, X.B.; Flake, D.D.; Sasso, E.H. & Huizinga, T.W. (2019), Predicting risk for radiographic damage in rheumatoid arthritis: comparative analysis of the multi-biomarker disease activity score and conventional measures of disease activity in multiple studies, Current Medical Research and Opinion.
- Chadli, L.; Sotthewes, B.; Li, K.J.; Andersen, S.N.; Cahir-McFarland, E.; Cheung, M.; Cullen, P.; Dorjee, A.; Vries-Bouwstra, J.K. de; Huizinga, T.W.J.; Fischer, D.F.; DeGroot, J.; Viney, J.L.; Zheng, T.S.; Aarbiou, J. & Gardet, A. (2019), Identification of regulators of the myofibroblast phenotype of primary dermal fibroblasts from early diffuse systemic sclerosis patients, Scientific Reports 9.
- Dekkers, J.S.; Bergstra, S.A.; Chopra, A.; Tikly, M.; Fonseca, J.E.; Salomon-Escoto, K.; Huizinga, T.W.J. & Woude, D. van der (2019), Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis, Rheumatology 58(1): 149-153.
- Hafkenscheid, L.; Moel, E. de; Smolik, I.; Tanner, S.; Meng, X.B.; Jansen, B.C.; Bondt, A.; Wuhrer, M.; Huizinga, T.W.J.; Toes, R.E.M.; El-Gabalawy, H. & Scherer, H.U. (2019), N-Linked Glycans in the Variable Domain of IgG Anti-Citrullinated Protein Antibodies Predict the Development of Rheumatoid Arthritis, Arthritis and Rheumatology.
- Curtis Jeffrey R., Lin Yong, Thangavelu Karthinathan, Stanislav Marina, St John Gregory, Gomez-Centeno Antonio, Selmi Carlo, Huizinga Thomas, Antonio Maldonado-Cocco Jose, Bukhari Marwan & Buttgereit Frank (2019), WITHDRAWAL OF CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS IN THE SARILUMAB OPEN-LABEL EXTEND STUDY: EFFICACY AND SAFETY ANALYSIS, Annals of the Rheumatic Diseases 78: 702-703.
- Curtis Jeffrey R., Weinblatt Michael E., Shadick Nancy, Brahe Cecilie Heegaard, Ostergaard Mikkel, Hetland Merete L., Saevarsdottir Saedis, Horton Megan, Mabey Brent, Flake Darl, Sasso Eric H. & Huizinga Thomas (2019), VALIDATION OF THE ADJUSTED MULTI-BIOMARKER DISEASE ACTIVITY SCORE FOR PREDICTING RISK OF RADIOGRAPHIC PROGRESSION FOR PATIENTS WITH RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 78: 300-301.
- Hem-van Mil, A.H.M. van der; Huizinga, T.W.J. & Bloem, J.L. (2019), Treat-to-Target Strategies in Rheumatoid Arthritis, Journal of the American Medical Association 322(1): 83-83.
- Ciaffi Jacopo, van Leeuwen Nina, de Vries-Bouwstra Jeska & Huizinga Thomas (2019), THE IMPACT OF SMOKING ON NAILFOLD MICROANGIOPATHY AND AUTOANTIBODY STATUS IN MALE AND FEMALE PATIENTS WITH SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 78: 1211-1211.
- Kristyanto Hendy, van der Voort Ellen, Kerkman Priscilla, Burgers Leonie, Ten Brinck Robin, van der Helm-van Mil Annette, Baeten Dominique, Huizinga Thomas, Toes Rene & Scherer Hans Ulrich (2019), THE IMMUNE-PATHOGENIC CHARACTERISTICS OF AUTOREACTIVE B CELLS AGAINST CITRULLINATED ANTIGENS IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 78: 1079-1079.
- Curtis Jeffrey R., St John Gregory, Pannucci Michael, Lin Yong, Maldonado-Cocco Jose A., Huizinga Thomas, Stanislav Marina, Wilson Elaine & Emery Paul (2019), REDUCTIONS IN ABSOLUTE NEUTROPHIL COUNT WITH SARILUMAB RESULTING IN DOSE DELAYS OR DOSE DECREASES: EFFECTS ON EFFICACY AND SAFETY, Rheumatology 58: 73-73.
- Boonstra, M.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J.; Scherer, H.U. & Vries-Bouwstra, J.K. de (2019), Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria, Rheumatology 58(4): 730-732.
- Bijnen, S. van; Boonstra, M.; Enden, C. van den; Spierings, J.; Schouffoer, A.; Laar, J.M. van; Huizinga, T.; Voskuyl, A.; Velden, W. van der; Hoogen, F. van den; Vries, J. de & Vonk, M. (2019), PREDICTIVE FACTORS FOR TREATMENT RELATED MORTALITY AND MAJOR ADVERSE EVENTS AFTER AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR SYSTEMIC SCLEROSIS: RESULTS OF A LONG TERM FOLLOW-UP MULTI-CENTRE STUDY, Annals of the Rheumatic Diseases 78: 1206-1206.
- Gegenava, M.; Beaart, H.J.L.; Monahan, R.C.; Brilman, E.; Beaart-van de Voorde, L.J.J.; Magro-Checa, C.; Huizinga, T.W.J. & Steup-Beekman, G.M. (2019), Performance of the proposed ACR-EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms, RMD Open 5(1).
- Takata, M.; Pachera, E.; Frank-Bertoncelj, M.; Kozlova, A.; Jungel, A.; Whitfield, M.L.; Assassi, S.; Calcagni, M.; Vries-Bouwstra, J. de; Huizinga, T.W.; Kurreeman, F.; Kania, G. & Distler, O. (2019), OTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis, Frontiers in Immunology 10.
- Bykerk, V.P.; Burmester, G.R.; Combe, B.G.; Furst, D.E.; Huizinga, T.W.J.; Ahmad, H.A. & Emery, P. (2019), On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis (vol 38, pg 2225, 2018), Rheumatology International 39(5): 945-945.
- Hafkenscheid Lise, de Moel Emma C., Smolik Irene, Meng Xiaobo, Tanner Stacy, Jansen Bas C., Bondt Albert, Wuhrer Manfred, Huizinga Thomas, Toes Rene, El-Gabalawy Hani & Scherer Hans Ulrich (2019), N-LINKED GLYCANS IN THE VARIABLE DOMAIN OF ACPA-IGG IN THE DEVELOPMENT OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 78: 228-229.
- Monahan Rory, Beaart H. J. L., Gegeneva Maka, Brilman E. G., Beaart-van de Voorde L. J. J., Checa Cesar Magro, Huizinga Thomas & Steup-Beekman G. M. (2019), LOW SPECIFICITY OF THE PROPOSED 2017 ACR-EULAR CLASSIFICATION CRITERIA FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) COMPARED TO PREVIOUS CRITERIA IN SLE PATIENTS WITH NEUROPSYCHIATRIC SYMPTOMS, Annals of the Rheumatic Diseases 78: 399-400.
- van Hoogstraten Hubert, St John Gregory, Thangavelu Karthinathan, Jose Gomez-Reino Juan, Antonio Maldonado-Cocco Jose, Carlos Salazar Juan, Huizinga Thomas, Wilson Elaine & Burmester Gerd R. (2019), LONG-TERM TREATMENT WITH SARILUMAB PLUS CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS (CSDMARDS): POOLED SAFETY AND EFFICACY WITH OVER 4 YEARS' TREATMENT, Rheumatology 58: 74-75.
- Kraaij Tineke, Arends E. J., van Dam Laura, Kamerling Sylvia, van Daele Paul L. A., Bredewold Obbo Winne, Ray Argho, Bakker Jaap, Bajema Ingeborg, Scherer Hans Ulrich, Huizinga Thomas, Rabelink Ton, van Kooten Cees & Teng Y. K. Onno (2019), LONG-TERM EFFECTS OF SYNERGETIC B CELL IMMUNOMODULATION WITH RITUXIMAB AND BELIMUMAB COMBINATION TREATMENT IN SEVERE, REFRACTORY SLE: TWO YEAR RESULTS, Annals of the Rheumatic Diseases 78: 91-92.
- Quistrebert, J.; Hassler, S.; Bachelet, D.; Mbogning, C.; Musters, A.; Tak, P.P.; Wijbrandts, C.A.; Herenius, M.; Bergstra, S.A.; Akdemir, G.; Johannesson, M.; Combe, B.; Fautrel, B.; Chollet-Martin, S.; Gleizes, A.; Donnellan, N.; Deisenhammer, F.; Davidson, J.; Hincelin-Mery, A.; Donnes, P.; Fogdell-Hahn, A.; Vries, N. de; Huizinga, T.; Abugessaisa, I.; Saevarsdottir, S.; Hacein-Bey-Abina, S.; Pallardy, M.; Broet, P.; Mariette, X. & ABIRISK Consortium (2019), Incidence and risk factors for adalimumab and infliximab anti-drug antibodies in rheumatoid arthritis: A European retrospective multicohort analysis, Seminars in Arthritis and Rheumatism 48(6): 967-975.
- Bergstra Sytske Anne, Couto Maura, Govind Nimmisha, Chopra Arvind, Solomon-Escoto Karen, Murphy Elizabeth, Huizinga Thomas & Allaart Cornelia (2019), IMPACT OF THE COMBINED PRESENCE OF EROSIONS AND ACPA ON 6 AND 12 MONTHS CLINICAL OUTCOMES OF RHEUMATOID ARTHRITIS : RESULTS FROM THE METEOR REGISTRY, Annals of the Rheumatic Diseases 78: 1102-1103.
- Burgers, L.E.; Pol, J.A. van der; Huizinga, T.W.J.; Allaart, C.F. & Helm-van Mil, A.H.M. van der (2019), Does treatment strategy influence the ability to achieve and sustain DMARD-free remission in patients with RA? Results of an observational study comparing an intensified DAS-steered treatment strategy with treat to target in routine care, Arthritis Research and Therapy 21.
- Kampstra, A.S.B.; Dekkers, J.S.; Volkov, M.; Dorjee, A.L.; Hafkenscheid, L.; Kempers, A.C.; Delft, M. van; Kissel, T.; Reijm, S.; Janssen, G.M.C.; Veelen, P.A. van; Bang, H.; Huizinga, T.W.J.; Trouw, L.A.; Woude, D. van der & Toes, R.E.M. (2019), Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification, Annals of the Rheumatic Diseases 78(7): 908-916.
- Lubbers, R.; Beaart-van De Voorde, L.J.J.; Leeuwen, K. van; Boer, M. de; Gelderman, K.A.; Berg, M.J. van den; Ketel, A.G.; Simon, A.; Ree, J. de; Huizinga, T.W.J.; Steup-Beekman, G.M. & Trouw, L.A. (2019), Complex medical history of a patient with a compound heterozygous mutation in C1QC, Lupus.
- Wortel, C.M.; Leeuwen, N.M. van; Boonstra, M.; Bakker, J.A.; Toes, R.E.; Huizinga, T.W.; Vries-Bouwstra, J.K. de & Scherer, H.U. (2019), CHARACTERIZATION OF THE ANTI-CENTROMERE ANTIBODY RESPONSE IN SYSTEMIC SCLEROSIS PATIENTS SUGGESTS A BROAD AND ACTIVE B CELL RESPONSE, Annals of the Rheumatic Diseases 78: A22-A22.
- Torrente-Segarra Vicenc, Huizinga Thomas, Solomon-Escoto Karen, Da Silva Jose Antonio P., Veale Douglas, Al Emadi Samar & Bergstra Sytske Anne (2019), BIOLOGICAL THERAPIES SURVIVAL IN RHEUMATOID ARTHRITIS PATIENTSIN CLINICAL PRACTICE: RESULTS FROM THE METEOR REGISTRY, Annals of the Rheumatic Diseases 78: 730-730.
- Maarseveen Tjardo, Huizinga Thomas, van den Akker Erik & Knevel Rachel (2019), A VALIDATED TEXT-MINING ALGORITHM TO EXTRACT RA MEDICATION CONTAINED IN FORMAT-FREE FIELDS OF EMRS, Annals of the Rheumatic Diseases 78: 1387-1388.
- Maarseveen Tjardo, Huizinga Thomas, Reinders Marcel, van den Akker Erik & Knevel Rachel (2019), AUTOMATED DIAGNOSIS EXTRACTION FROM ELECTRONIC MEDICAL RECORDS WITH MACHINE LEARNINGCLASSIFIERS, Annals of the Rheumatic Diseases 78: 1388-1389.
- van Leeuwen Nina, Bakker Jaap, Wortel Corrie, Scherer Hans Ulrich, Toes Rene, Huizinga Thomas & de Vries-Bouwstra Jeska (2019), ASSOCIATION BETWEEN CENTROMERE AND TOPOISOMERASE SPECIFIC IMMUNE RESPONSES AND THE DEGREE OF MICROANGIOPATHY IN SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 78: 1568-1568.
- Al-Laith, M.; Jasenecova, M.; Abraham, S.; Bosworth, A.; Bruce, I.N.; Buckley, C.D.; Ciurtin, C.; D'Agostino, M.A.; Emery, P.; Gaston, H.; Isaacs, J.D.; Filer, A.; Fisher, B.A.; Huizinga, T.W.J.; Ho, P.; Jacklin, C.; Lempp, H.; McInnes, I.B.; Pratt, A.G.; Ostor, A.; Raza, K.; Taylor, P.C.; Schaardenburg, D. van; Shivapatham, D.; Wright, A.J.; Vasconcelos, J.C.; Kelly, J.; Murphy, C.; Prevost, A.T. & Cope, A.P. (2019), Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol, Trials 20.
- Leeuwen, N. van; Boonstra, M.; Bakker, J.; Wortel, C.; Scherer, H.U.; Toes, R.; Huizinga, T. & Vries-Bouwstra, J. de (2019), AN ONGOING ANTICENTROMERE ANTIBODY RESPONSE ASSOCIATES WITH PROGRESSION TOWARDS SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 78: 2111-2111.
- Matthijssen Xanthe, Niemantsverdriet Ellis, Huizinga Thomas & van der Helm-van Mil Annette (2019), ACPA-POSITIVE RHEUMATOID ARTHRITIS PATIENTS BENEFITED MORE FROM ADVANCED TREATMENT STRATEGIES THAN ACPA-NEGATIVE RHEUMATOID ARTHRITISPATIENTS: 25-YEAR RESULTS OF A LONGITUDINAL COHORT STUDY, Annals of the Rheumatic Diseases 78: 79-80.
- Boeters, D.M.; Burgers, L.E.; Sasso, E.H.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2019), ACPA-negative RA consists of subgroups: patients with high likelihood of achieving sustained DMARD-free remission can be identified by serological markers at disease presentation, Arthritis Research and Therapy 21.
- Maurits Marc, Huizinga Thomas, Raychaudhuri Soumya, Reinders Marcel, Karlson Elizabeth, van den Akker Erik & Knevel Rachel (2019), A BIG-DATA APPROACH TO ELECTRONIC HEALTH RECORD DATA - USING DIMENSIONALITY REDUCTION AND CLUSTERING TECHNIQUES TO STUDY LONGITUDINAL RELATIONSHIPS BETWEEN DISEASES, Annals of the Rheumatic Diseases 78: 2102-2102.
- Al-Laith, M.; Jasenecova, M.; Abraham, S.; Bosworth, A.; Bruce, I.N.; Buckley, C.D.; Ciurtin, C.; D'Agostino, M.A.; Emery, P.; Gaston, H.; Isaacs, J.D.; Filer, A.; Fisher, B.A.; Huizinga, T.W.J.; Ho, P.; Jacklin, C.; Lempp, H.; McInnes, I.B.; Pratt, A.G.; Ostor, A.; Raza, K.; Taylor, P.C.; Schaardenburg, D. van; Shivapatham, D.; Wright, A.J.; Vasconcelos, J.C.; Kelly, J.; Murphy, C.; Prevost, A.T. & Cope, A.P. (2019), Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol, Trials 20.
- Leeuwen, N.M. van; Boonstra, M.; Marsan, N.A.; Ninaber, M.K.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2019), Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening.
- Kissel, T.; Schie, K.A. van; Hafkenscheid, L.; Lundquist, A.; Kokkonen, H.; Wuhrer, M.; Huizinga, T.W.J.; Scherer, H.U.; Toes, R. & Rantapaa-Dahlqvist, S. (2019), On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis, Annals of the Rheumatic Diseases 78(12): 1616-1620.
- Moel, E.C. de; Rozeman, E.A.; Kapiteijn, E.H.; Verdegaal, E.M.E.; Grummels, A.; Bakker, J.A.; Huizinga, T.W.J.; Haanen, J.B.; Toes, R.E.M. & Woude, D. van der (2019), Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors, Cancer Immunology Research 7(1): 6-11.
- Magro-Checa, C.; Kumar, S.; Ramiro, S.; Beaart-van de Voorde, L.J.; Eikenboom, J.; Ronen, I.; Bresser, J. de; Buchem, M.A. van; Huizinga, T.W. & Steup-Beekman, G.M. (2019), Are serum autoantibodies associated with brain changes in systemic lupus erythematosus? MRI data from the Leiden NP-SLE cohort, Lupus 28(1): 94-103.
- Wijngaarden, S.E. van; Said-Bouyeri, S. ben; Ninaber, M.K.; Huizinga, T.W.J.; Schalij, M.J.; Bax, J.J.; Delgado, V.; Vries-Bouwstra, J.K. de & Marsan, N.A. (2019), Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study, Journal of Rheumatology 46(4): 405-415.
- Spiliopoulou, A.; Colombo, M.; Plant, D.; Nair, N.; Cui, J.; Coenen, M.J.H.; Ikari, K.; Yamanaka, H.; Saevarsdottir, S.; Padyukov, L.; Bridges, S.L.; Kimberly, R.P.; Okada, Y.; Riel, P.L.C.M. van; Wolbink, G.; Horst-Bruinsma, I.E. van der; Vries, N. de; Tak, P.P.; Ohmura, K.; Canhao, H.; Guchelaar, H.J.; Huizinga, T.W.J.; Criswell, L.A.; Raychaudhuri, S.; Weinblatt, M.E.; Wilson, A.G.; Mariette, X.; Isaacs, J.D.; Morgan, A.W.; Pitzalis, C.; Barton, A. & McKeigue, P. (2019), Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39, Annals of the Rheumatic Diseases 78(8): 1055-1061.
- Ciaffi, J.; Leeuwen, N.M. van; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2019), Cumulative endogenous estrogen exposure is not associated with severity of peripheral microangiopathy in patients with systemic sclerosis, Clinical and Experimental Rheumatology 37(4): S82-S87.
- Leeuwen, N.M. van; Boonstra, M.; Marsan, N.A.; Ninaber, M.K.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2019), Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening, The Journal of Rheumatology 46(9): 1244-1245.
- Bergstra, S.A.; Couto, M.C.; Govind, N.; Chopra, A.; Escoto, K.S.; Murphy, E.; Huizinga, T.W.J. & Allaart, C.F. (2019), Impact of the combined presence of erosions and ACPA on rheumatoid arthritis disease activity over time: results from the METEOR registry, RMD Open 5(2).
- Emery, P.; Burmester, G.R.; Bykerk, V.P.; Combe, B.G.; Furst, D.E.; Maldonado, M.A. & Huizinga, T.W.J. (2019), Re-treatment with abatacept plus methotrexate for disease flare after complete treatment withdrawal in patients with early rheumatoid arthritis: 2-year results from the AVERT study, RMD Open 5(1).
- Boonstra, M.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J.; Scherer, H.U. & Vries-Bouwstra, J.K. de (2019), Prognostic properties of anti-topoisomerase antibodies in patients identified by the ACR/EULAR 2013 systemic sclerosis criteria.
- Boer, A.C.; Huizinga, T.W.J. & Helm-van Mil van der (2019), Depression and anxiety associate with less remission after 1 year in rheumatoid arthritis, Annals of the Rheumatic Diseases 78(1).
- Emery P, Tanaka Y, Bykerk V, Bingham C, Huizinga T, Citera G, Connolly S, Huang KHG, Elbez Y, Mukherjee S & Fleischmann R (2019), Reduction in CD4 TEMRA Cells and Its Association with DAS28 (CRP) < 2.6 Treatment Response with Abatacept in Patients with Early, ACPA plus , DMARD-Naive RA, Arthritis and Rheumatology 71.
- Bijnen, S. van; Boonstra, M.; Ende, E. van den; Kroft, L.; Geurts, B.; Snoeren, M.; Oer, A.S.; Spierings, J.; Laar, J. van; Huizinga, T.; Voskuyl, A.; Velden, W. van der; Hoogen, F. van den; Vries-Bouwstra, J. de & Vonk, M. (2019), Predictive Factors for Treatment Related Mortality and Event-Free Survival After Autologous Hematopoietic Stem Cell Transplantation for Systemic Sclerosis: Results of a Long Term Follow-up Multi-centre Study, Arthritis and Rheumatology 71.
- Moel, E.C. de; Derksen, V.F.A.M.; Trouw, L.A.; Bang, H.; Collee, G.; Lard, L.R.; Ramiro, S.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2019), In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response, Arthritis Research and Therapy 21.
- Emery P, Tanaka Y, Bykerk V, Bingham C, Huizinga T, Citera G, Zhuo J, Huang KHG, Wong R, Connolly S, Elbez Y & Fleischmann R (2019), Patient-Reported Outcomes of Abatacept in Combination with MTX in Early, MTX-Naive, ACPA Positive Patients with RA: 1-Year Results from a Phase IIIb Study, Arthritis and Rheumatology 71.
- Emery P, Tanaka Y, Bykerk V, Huizinga TWJ, Citera G, Bingham C, Banerjee S, Soule B, Nys M, Connolly S, Wong R, Huang KHG & Fleischmann R (2019), Maintenance of Remission Following Dose De-Escalation of Abatacept in Early, MTX-Naive, ACPA-Positive Patients with RA: Results from a Randomized Phase IIIb Study, Arthritis and Rheumatology 71.
- Kissel, T.; Schie, K.A. van; Hafkenscheid, L.; Lundquist, A.; Kokkonen, H.; Wuhrer, M.; Huizinga, T.W.J.; Scherer, H.U.; Toes, R. & Rantapaa-Dahlqvist, S. (2019), On the presence of HLA-SE alleles and ACPA-IgG variable domain glycosylation in the phase preceding the development of rheumatoid arthritis, Annals of the Rheumatic Diseases 78(12): 1616-1620.
- Huizinga T, Toes R, Weinblatt M, Schiff M, Fleischmann R, Elbez Y, Connolly S, Maldonado M & Gao S (2019), Effect of ACPA IgM Serostatus on Efficacy Outcomes Following Treatment with Abatacept or Adalimumab: A Post Hoc Analysis of a Phase III Head-to-Head Trial, Arthritis and Rheumatology 71.
- Emery P, Tanaka Y, Bykerk V, Bingham C, Huizinga T, Citera G, Huang KHG, Connolly S, Elbez Y, Lozenski K & Fleischmann R (2019), Baseline Characteristics Associated with Sustained SDAI Remission Following Treatment with Abatacept in Combination with MTX Compared with Abatacept Placebo in Combination with MTX in ACPA Positive Patients with Early RA, Arthritis and Rheumatology 71.
- van Leeuwen N, Fretheim H, Molberg O, Huizinga T, de Vries-Bouwstra J & Hoffmann-Vold AM (2019), Severity and Evolution over Time of Gastro-Intestinal Involvement in Patients with Systemic Sclerosis in Two Large and Independent Cohorts, Arthritis and Rheumatology 71.
- de Moel E, Rech J, Mahler M, Roth J, Schouffoer A, Ronday K, Huizinga T, Allaart CF, Toes R, Schett G & van der Woude D (2019), Serum Calprotectin Is a Prognostic Marker for Drug-Free Remission in RA, Arthritis and Rheumatology 71.
- Magro-Checa, C.; Kumar, S.; Ramiro, S.; Beaart-van de Voorde, L.J.; Eikenboom, J.; Ronen, I.; Bresser, J. de; Buchem, M.A. van; Huizinga, T.W. & Steup-Beekman, G.M. (2019), Are serum autoantibodies associated with brain changes in systemic lupus erythematosus? MRI data from the Leiden NP-SLE cohort, Lupus 28(1): 94-103.
- Maassen JM, Goekoop YPM, van Groenendael JHLM, Lems WF, Kerstens PJSM, Huizinga T & Allaart CF (2019), Mortality of Rheumatoid Arthritis Patients, Treated to Target at Low Disease Activity: 17-years Follow-up of the BeSt Cohort, Arthritis and Rheumatology 71.
- Ciaffi, J.; Leeuwen, N. van; Boonstra, M.; Kroft, L.; Schouffoer, A.; Ninaber, M.; Huizinga, T. & Vries-Bouwstra, J. de (2019), Evolution of Systemic Sclerosis-Related Interstitial Lung Disease After Autologous Hematopoietic Stem Cell Transplantation, Arthritis and Rheumatology 71.
- Toes R, Lehman T, Bryson J, Kim AM, Balachandar S, Mukherjee S, Maldonado M, Connolly S & Huizinga T (2019), Change in Rheumatoid Arthritis (RA)-Related Autoantibody Profile and Risk of Disease Flare After Withdrawal of Therapy in Patients with Early RA Treated with Abatacept and MTX, Arthritis and Rheumatology 71.
- Maarseveen T, Huizinga T, Reinders MJT, van den Akker E & Knevel R (2019), A Validated Text-mining Algorithm to Extract Rheumatoid Arthritis Medication Contained in Format-free Fields of Electronic Medical Records, Arthritis and Rheumatology 71.
- Akdemir, G.; Markusse, I.M.; Bergstra, S.A.; Goekoop, R.J.; Molenaar, E.T.; Groenendael, J.H.L.M. van; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2018), Comparison between low disease activity or DAS remission as treatment target in patients with early active rheumatoid arthritis, RMD Open: Rheumatic and Musculoskeletal Diseases 4(1).
- Jansen, D.T.S.L.; Emery, P.; Smolen, J.S.; Westhovens, R.; Bars, M. le; Connolly, S.E.; Ye, J.; Toes, R.E.M. & Huizinga, T.W.J. (2018), Conversion to seronegative status after abatacept treatment in patients with early and poor prognostic rheumatoid arthritis is associated with better radiographic outcomes and sustained remission: post hoc analysis of the AGREE study, RMD Open: Rheumatic and Musculoskeletal Diseases 4(1).
- Knevel, R.; Terao, C.; Cui, J.; Slowikowski, K.; Huizinga, T.; Karlson, B.; Liao, K.; Cessie, S. le & Raychaudhuri, S. (2018), OPTIMISINGPRECISION MEDICINE BY USING GENETICS TO ASSIGN DIAGNOSTIC PRIOR PROBABILITIES TO PATIENTS WITH SYNOVITIS - PROOF OF PRINCIPLE, Annals of the Rheumatic Diseases 77: 226-227.
- Kloppenburg, M.; Ramonda, R.; Bobacz, K.; Kwok, W.Y.; Elewaut, D.; Huizinga, T.W.J.; Kroon, F.P.B.; Punzi, L.; Smolen, J.S.; Cruyssen, B.V.; Wolterbeek, R.; Verbruggen, G. & Wittoek, R. (2018), Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial, Annals of the Rheumatic Diseases 77(12): 1757-1764.
- Volkov, M.; Dekkers, J.; Loos, B.G.; Bizzarro, S.; Huizinga, T.W.J.; Praetorius, H.A.; Toes, R.E.M. & Woude, D. van der (2018), Comment on "Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis", Science Translational Medicine 10(433).
- Edwards, C.J.; Fautrel, B.; Schulze-Koops, H.; Huizinga, T.W.J. & Kruger, K. (2018), Dosing down with biologic therapies: a systematic review and clinicians' perspective (vol 56, pg 1847, 2017), Rheumatology 57(3): 589-589.
- Brouwers H., von Hegedus J. H., Toes R. E. M., Huizinga T. W. J., Giera M. A., Kloppenburg M. & Ioan-Facsinay A. (2018), THE IMPORTANCE OF PROPER HANDLING OF HUMAN SYNOVIAL FLUID FOR ARTHRITIS RESEARCH, Annals of the Rheumatic Diseases 77: 880-880.
- Kempers, A.C.; Hafkenscheid, L.; Dorjee, A.L.; Moutousidou, E.; Bovenkamp, F.S. van de; Rispens, T.; Trouw, L.A.; Oosterhout, M. van; Huizinga, T.W.J.; Toes, R. & Scherer, H.U. (2018), The extensive glycosylation of the ACPA variable domain observed for ACPA-IgG is absent from ACPA-IgM, Annals of the Rheumatic Diseases 77(7): 1087-+.
- Delft, M.A.M. van; Verheul, M.K.; Burgers, L.E.; Rantapaa-Dahlqvist, S.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2018), The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching, Rheumatology 57(9): 1583-1591.
- Curtis Jeffrey R., St John Gregory, Pannucci Michael, Lin Yong, Maldonado-Cocco Jose A., Huizinga Tom W. J., Stanislav Marina & Emery Paul (2018), Reductions in Absolute Neutrophil Count (ANC) with Sarilumab Resulting in Dose Delays or Dose Decreases: Effects on Efficacy and Safety, Arthritis and Rheumatology 70.
- Danilin S., Schordan E., Coq M., Abbinazi S. Ait, Mehdi M., Firat H., Arber N., Breuil V., Demoux A. -L., Gul A., Gottenberg J. -E., Hatemi G., Huizinga T., Inanc N., Vencovsky J. & Jorgensen C. (2018), RABIOPRED, AN INNOVATIVE THERANOSTIC TOOL TO ASSIST CLINICIANS SELECT AN OPTIMAL ANTI-TNF ALPHA BIOLOGICAL THERAPY FOR RHEUMATOID ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 77: 857-857.
- Bykerk, V.P.; Burmester, G.R.; Combe, B.G.; Furst, D.E.; Huizinga, T.W.J.; Ahmad, H.A. & Emery, P. (2018), On-drug and drug-free remission by baseline symptom duration: abatacept with methotrexate in patients with early rheumatoid arthritis, Rheumatology International 38(12): 2225-2231.
- Boonstra, M.; Noordhoek, D.C.; Beaart-van de Voorde, L.J.; Huizinga, T.W. & Vries-Bouwstra, J.K. de (2018), NORMALISATION OF NAILFOLD MICROVASCULATURE AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION IN SEVERE SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 77: 421-421.
- Vergroesen R. D., Slot L. M., van de Bovenkamp F. S., Koning M. T., Huizinga T. W., Rispens T., Toes R. E. M. & Scherer H. U. (2018), MOLECULAR ANALYSIS OF ANTI-CITRULLINATED PROTEIN ANTIBODY VARIABLE REGIONS INDICATES ABERRANT SELECTION PROCESSES DURING ACPA B-CELL DEVELOPMENT, Annals of the Rheumatic Diseases 77: 203-203.
- Genovese Mark C., van Hoogstraten Hubert, St John Gregory, Dong Qunming, Jose Gomez-Reino Juan, Maldonado-Cocco Jose A., Carlos Salazar Juan, Huizinga Tom W. J. & Burmester Gerd R. (2018), Long-Term Treatment with Sarilumab Plus Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs): Pooled Safety and Efficacy with over 4 Years' Treatment, Arthritis and Rheumatology 70.
- Boonstra, M.; Ninaber, M.K.; Marsan, N.A.; Scherer, H.U.; Huizinga, T.W.J. & Vries-Bouwstra, J. de (2018), Longitudinal Follow-up of Anti-Topoisomerase I Positive Patients within the Leiden Systemic Sclerosis Cohort - Prognosis Infaust?, Arthritis and Rheumatology 70.
- Magro-Checa, C.; Steup-Beekman, G.M.; Huizinga, T.W.; Buchem, M.A. van & Ronen, I. (2018), Laboratory and Neuroimaging Biomarkers in Neuropsychiatric Systemic Lupus Erythematosus: Where Do We Stand, Where To Go?, Frontiers in Medicine 5.
- Torrente-Segarra, V.; Bergstra, S.A.; Solomon-Escoto, K.; Silva, J.A.P.; Veale, D.J.; Al-Emadi, S. & Huizinga, T.W.J. (2018), Is current smoking status and its relationship to anti-cyclic citrullinated peptide antibodies a predictor of worse response to biological therapies in rheumatoid arthritis patients?, Scandinavian Journal of Rheumatology 47(5): 360-363.
- Moel, E.C. de; Derksen, V.F.A.M.; Stoeken, G.; Trouw, L.A.; Bang, H.; Goekoop, R.J.; Speyer, I.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2018), Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes, Arthritis Research and Therapy 20.
- Moel, E.C. de; Derksen, V.F.; Trouw, L.A.; Bang, H.; Goekoop-Ruiterman, Y.P.; Steup-Beekman, G.M.; Huizinga, T.W.; Allaart, C.F.; Toes, R.E. & Woude, D. van der (2018), IN RA, BECOMING SERONEGATIVE OVER THE 1ST YEAR OF DMARD TREATMENT DOES NOT TRANSLATE TO BETTER CHANCES OF DRUG-FREE REMISSION IN THE LONG-TERM, Annals of the Rheumatic Diseases 77: A16-A17.
- Huizinga Thomas W., Kay Jonathan, Harigai Masayoshi, Keystone Edward, Srnolen Josef, Rosase Jose, Emery Paul, Hall Stephen, van den Bosch Filip, Schienberg Morton, Dudler Jean, Liao Ran, Meszaros Gabriella, Barry Jane & Kremer Joel (2018), EFFECTS OF BARICITINIB ON HAEMATOLOGICAL LABORATORY PARAMETERS IN PATIENTS WITH RHEUMATOID ARTHRITIS, Rheumatology 57.
- Huizinga T., Kay J., Harigai M., Keystone E., Smolen J., Rosas J., Emery P., Hall S., van den Bosch F., Scheinberg M., Dudler J., Liao R., Meszaros G., Barry J. & Kremer J. (2018), EFFECTS OF BARICITINIB ON HAEMATOLOGICAL LABORATORY PARAMETERS IN PATIENTS WITH RHEUMATOID ARTHRITIS, Internal Medicine Journal 48: 42-42.
- Genovese M. C., Mangan E. K., Kimura T., Iglesias-Rodriguez M., van Hoogstraten H. & Huizinga T. W. J. (2018), DURATION OF RESPONSE IN A PHASE 3 STUDY OF SARILUMAB PLUS METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS (RA), Internal Medicine Journal 48: 20-21.
- Moel, E.C. de; Derksen, V.F.; Trouw, L.A.; Bang, H.; Goekoop, R.J.; Speyer, I.; Huizinga, T.W.; Allaart, C.F.; Toes, R.E. & Woude, D. van der (2018), BASELINE AUTOANTIBODY PROFILE IN RHEUMATOID ARTHRITIS ASSOCIATES WITH EARLY TREATMENT RESPONSE BUT NOT LONG-TERM OUTCOMES, Annals of the Rheumatic Diseases 77: A25-A25.
- Messemaker, T.C.; Chadli, L.; Cai, G.S.; Goelela, V.S.; Boonstra, M.; Dorjee, A.L.; Andersen, S.N.; Mikkers, H.M.M.; Van't Hof, P.; Mei, H.L.; Distler, O.; Draisma, H.H.M.; Johnson, M.E.; Orzechowski, N.M.; Simms, R.W.; Toes, R.E.M.; Aarbiou, J.; Huizinga, T.W.; Whitfield, M.L.; DeGroot, J.; Vries-Bouwstra, J. de & Kurreeman, F. (2018), Antisense Long Non-Coding RNAs Are Deregulated in Skin Tissue of Patients with Systemic Sclerosis, Journal of Investigative Dermatology 138(4): 826-835.
- Scherer, H.U.; Huizinga, T.W.J.; Kronke, G.; Schett, G. & Toes, R.E.M. (2018), The B cell response to citrullinated antigens in the development of rheumatoid arthritis, Nature Reviews Rheumatology 14(3): 157-169.
- Moel, E. de; Derksen, V.; Trouw, L.A.; Bang, H.; Collee, G.; Lard, L.R.; Huizinga, T.W.J.; Allaart, C.E.; Toes, R.E.M. & Woude, D. van der (2018), In Rheumatoid Arthritis, Changes in Autoantibody Levels Do Not Associate with Treatment Response, but Are a Reflection of Treatment Intensity, Arthritis and Rheumatology 70.
- Moel, E.C. de; Derksen, V.F.A.M.; Trouw, L.A.; Bang, H.; Goekoop-Ruiterman, Y.P.M.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2018), In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission, Annals of the Rheumatic Diseases 77(12): 1836-+.
- Moel, E.C. de; Derksen, V.F.A.M.; Trouw, L.A.; Bang, H.; Goekoop-Ruiterman, Y.P.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2018), IN RA, BECOMING SERONEGATIVE OVER THE 1ST YEAR OF DMARD TREATMENT DOES NOT TRANSLATE TO BETTER CHANCES OF SUSTAINED DRUG-FREE REMISSION IN THE LONG-TERM, Annals of the Rheumatic Diseases 77: 258-259.
- Stamm, T.A.; Machold, K.P.; Aletaha, D.; Alasti, F.; Lipsky, P.; Pisetsky, D.; Landewe, R.; Heijde, D. van der; Sepriano, A.; Aringer, M.; Boumpas, D.; Burmester, G.; Cutolo, M.; Ebner, W.; Graninger, W.; Huizinga, T.; Schett, G.; Schulze-Koops, H.; Tak, P.P.; Martin-Mola, E.; Breedveld, F. & Smolen, J. (2018), Induction of sustained remission in early inflammatory arthritis with the combination of infliximab plus methotrexate: the DINORA trial, Arthritis Research and Therapy 20.
- Boer, A.C.; Huizinga, T.W.J. & Helm-van Mil van der (2018), Depression and anxiety associate with less remission after 1 year in rheumatoid arthritis.
- Boeters D. M., Burgers L. E., Huizinga T. W. & van der Helm-van Mil A. H. (2018), A COMBINATION OF PROTEINS AS MEASURED WITHIN THE MULTI-BIOMARKER DISEASE ACTIVITY SCORE AT PRESENTATION OF RA IDENTIFIES A GROUP OF ACPA-NEGATIVE RA PATIENTS WITH HIGH LIKELIHOOD OF DEVELOPING DMARD-FREE SUSTAINED REMISSION, Annals of the Rheumatic Diseases 77: 135-135.
- Chopra Arvind, Saluja Manjit, Bergstra Sytske Anne, Kainifard Toktam, Venugopalan Anuradha & Huizinga Tom W. J. (2018), A Decade Earlier- Onset of Symptoms of RA in the Indian (Asian) Cohort Compared to Dutch Cohort: Based on Meteor, a Global Database, Arthritis and Rheumatology 70.
- Vergroesen, R.D.; Slot, L.M.; Hafkenscheid, L.; Koning, M.T.; Voort, E.I.H. van der; Grooff, C.A.; Zervakis, G.; Veelken, H.; Huizinga, T.W.J.; Rispens, T.; Scherer, H.U. & Toes, R.E.M. (2018), B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation, Annals of the Rheumatic Diseases 77(6): 955-+.
- Bergstra Sytske Anne, Couto Maura, Govind Nimmisha, Chopra Arvind, Salomon-Escoto Karen, Murphy Elizabeth, Huizinga Tom W. J. & Allaart Cornelia F. (2018), Impact of the Joint Presence of Erosions and ACPA on Rheumatoid Arthritis Disease Activity over Time: Results from the Meteor Registry, Arthritis and Rheumatology 70.
- Westra, H.J.; Martinez-Bonet, M.; Onengut-Gumuscu, S.; Lee, A.; Luol, Y.; Teslovich, N.; Worthington, J.; Martin, J.; Huizinga, T.; Klareskog, L.; Rantapaa-Dahlqvist, S.; Chen, W.M.; Quinlan, A.; Todd, J.A.; Eyre, S.; Nigrovic, P.A.; Regersen, P.K.G.; Rich, S.S. & Raychaudhuri, S. (2018), Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes, Nature Genetics 50(10): 1366-+.
- Bergstra Sytske Anne, van der Pol Joy A., Riyazi Nagmeh, Goekoop-Ruiterman Yvonne P., Chopra Arvind, da Silva Jose Antonio P., Kerstens Pit J. S. M., Lems Willem F., Tsonaka S., Huizinga Tom W. J. & Allaart Cornelia F. (2018), Window or No Window? Earlier Is Better When Treating Rheumatoid Arthritis, Arthritis and Rheumatology 70.
- van der Pol J. A., Bergstra S. A., Riyazi N., Goekoop-Ruiterman Y. P., Chopra A., Kerstens P., Lems W. F., Tsonaka R., Huizinga T. W. & Allaart C. F. (2018), WINDOW OR NO WINDOW: EARLIER IS BETTER WHEN TREATING RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 77: 910-911.
- Kempers, A.C.; Nejadnik, M.R.; Rombouts, Y.; Ioan-Facsinay, A.; Oosterhout, M. van; Jiskoot, W.; Huizinga, T.W.J.; Toes, R.E.M. & Scherer, H.U. (2018), Fc gamma receptor binding profile of anti-citrullinated protein antibodies in immune complexes suggests a role for Fc gamma RI in the pathogenesis of synovial inflammation, Clinical and Experimental Rheumatology 36(2): 284-293.
- Burmestert Gerd R., Hagino Owen, Dong Qunming, Stanislav Marina, Gomez-Centeno Antonio, Selmi Carlo, Huizinga Tom W. J., Mangan Erin, Gabay Cem & Genovese Mark C. (2018), Unique Changes in Hemoglobin with Sarilumab Versus Adalimumab Are Independent of Better Disease Control in Patients with Rheumatoid Arthritis (RA), Arthritis and Rheumatology 70.
- Ahmad H. A., Baker J. F., Ostergaard M., Emery P., Huizinga T., Elbez Y., Banerjee S. & Conaghan P. G. (2018), EXCEEDING PREDEFINED THRESHOLDS FOR MRI BONE OEDEMA AND EROSION AND HAQ-DI CAN PREDICT RELAPSE AFTER WITHDRAWAL OF ALL TREATMENT IN MTX-NAIVE PATIENTS WITH RA IN REMISSION AFTER 12 MONTHS OF ABATACEPT THERAPY IN THE AVERT TRIAL, Annals of the Rheumatic Diseases 77: 568-569.
- Teng, Y.K.O.; Bredewold, E.O.W.; Rabelink, T.J.; Huizinga, T.W.J.; Eikenboom, H.C.J.; Limper, M.; Fritsch-Stork, R.D.E.; Bloemenkamp, K.W.M. & Sueters, M. (2018), An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus, Rheumatology 57(10): 1707-1720.
- Derksen, V.F.A.M.; Westerlind, H.; Saevarsdottir, S.; Ajeganova, S.; Trouw, L.A.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Knevel, R. & Woude, D. van der (2018), Anti-Carbamylated Protein Antibodies and Higher Baseline Disease Activity in Rheumatoid Arthritis-A Replication Study in Three Cohorts: Comment on the Article by Truchetet et al, Arthritis and Rheumatology 70(12): 2096-2097.
- Baecklund, E.; Backlin, C.; Ronnelid, J.; Toes, R.; Huizinga, T.W.J.; Ahlin, E.; Askling, J.; Hochberg, F.H.; Klareskog, L.; Kay, J. & Smedby, K.E. (2018), Anti-cyclic citrullinated peptide antibodies, other common autoantibodies, and smoking as risk factors for lymphoma in patients with rheumatoid arthritis, Scandinavian Journal of Rheumatology 47(4): 270-275.
- de Moel Emma, Amkreutz Josephine, Heimans Lotte, Allaart Cornelia F., Huizinga Tom W. J. & van der Woude Diane (2018), Are ACPA Associated with More Bone Loss over Time in Patients with RA?, Arthritis and Rheumatology 70.
- Amkreutz J. A. M. P., de Moel E. C., Heimans L., Allaart C. F., Huizinga T. W. J. & van der Woude D. (2018), ARE ACPA ASSOCIATED WITH MORE BONE LOSS OVER TIME IN PATIENTS WITH RA?, Annals of the Rheumatic Diseases 77: 1307-1307.
- Shaukat Amara, Gosling Anna, Bixley Matthew, Phipps-Green Amanda, Major Tanya J., Cadzow Murray, Dalbeth Nicola, Stamp Lisa K., Matisoo-Smith Elizabeth, Hindmarsh Jennie Harre, Joosten Leo A. B., Jansen Tim, Janssen Matthijs, Tausche Anne-Kathrin, Riches Philip, So Alexander, Andres Mariano, McCarthy Geraldine M., Perez-Ruiz Fernando, Doherty Michael, Torres Rosa, Huizinga Tom W. J., Knevel Rachel, Kurreeman Fina & Merriman Tony R. (2018), Evaluating a Causal Role of Mitochondrial Variation in the Development of Gout, Arthritis and Rheumatology 70.
- Dekkerst J. S., Bergstra S. A., Chopra A., Tikly M., Fonseca J. E., Salomon-Escoto K., Huizinga T. & van der Woude D. (2018), AUTOANTIBODY STATUS IS NOT ASSOCIATED WITH EARLY TREATMENT RESPONSE TO FIRST-LINE METHOTREXATE IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 77: 843-844.
- Habers G. Esther A., Veldhuijzen D. S., Allaart C. F., van der Helm A. H. M., Vreugdenhil E., Huizinga T. W. J. & Evers A. W. M. (2018), Bright Light Therapy in Rheumatoid Arthritis to Improve Symptoms of Fatigue and Other Disease Outcomes: A Randomized Controlled Pilot Trial, Neuropsychobiology 76(1): 18-18.
- Genovese, M.C.; Adelsberg, J. van; Fan, C.P.; Graham, N.M.H.; Hoogstraten, H. van; Parrino, J.; Mangan, E.K.; Spindler, A.; Huizinga, T.W.J.; Heijde, D. van der & EXTEND Study Investigators (2018), Two years of sarilumab in patients with rheumatoid arthritis and an inadequate response to MTX: safety, efficacy and radiographic outcomes, Rheumatology 57(8): 1423-1431.
- Verheul, M.K.; Bohringer, S.; Delft, M.A.M. van; Jones, J.D.; Rigby, W.F.C.; Gan, R.W.; Holers, V.M.; Edison, J.D.; Deane, K.D.; Janssen, K.M.J.; Westra, J.; Brink, M.; Rantapaa-Dahlqvist, S.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Woude, D. van der; Toes, R.E.M. & Trouw, L.A. (2018), Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis: Implications for Very Early Identification of At-Risk Individuals, Arthritis and Rheumatology 70(11): 1721-1731.
- Boonstra, M.; Bakker, J.A.; Grummels, A.; Ninaber, M.K.; Marsan, N.A.; Scherer, H.U.; Toes, R.E.; Huizinga, T.W. & Vries-Bouwstra, J.K. de (2018), CONTINUOUS PRESENCE OF IGM ANTI-TOPOISOMERASE I ANTIBODIES INDICATES AN ONGOING IMMUNE RESPONSE IN SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 77: 755-755.
- de Moel Emma, Rozeman Elisa, Kapiteijn Ellen, Verdegaal Els, Grummels Annette, Bakker Jaap A., Huizinga Tom W. J., Haanen John, Toes Rene E. M. & van der Woude Diane (2018), Treatment with Immune Checkpoint Inhibitors and the Development of Autoantibodies, Arthritis and Rheumatology 70.
- de Moel E. G., Rozeman L., Grummels A., Verdegaal E. M. E., Bakker J. A., Kapiteijn E. H., Huizinga T. W. J., Haanen J. B., Toes R. E. M. & van der Woude D. (2018), TREATMENT WITH IMMUNE CHECKPOINT INHIBITORS AND THE BREAK OF B-CELL TOLERANCE TO AUTOANTIGENS, Annals of the Rheumatic Diseases 77: 240-240.
- Boonstra, M.; Mertens, B.J.A.; Bakker, J.A.; Ninaber, M.K.; Marsan, N.A.; Helm-van Mil, A.H.M. van der; Scherer, H.U.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2018), To what extent do autoantibodies help to identify high-risk patients in systemic sclerosis?, Clinical and Experimental Rheumatology 36(4): S109-S117.
- Kraaij, T.; Kamerling, S.W.A.; Rooij, E.N.M. de; Daele, P.L.A. van; Bredewold, O.W.; Bakker, J.A.; Bajema, I.M.; Scherer, H.U.; Toes, R.E.M.; Huizinga, T.J.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2018), The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus, Journal of Autoimmunity 91: 45-54.
- Rochelle D. Vergroesen, Linda M. Slot, Lise Hafkenscheid, Theresa Kissel, Fleur S. van de Bovenkamp, Marvyn T. Koning, Tom W.J. Huizinga, Theo Rispens, Hans U. Scherer & René E.M. Toes (2018), Introduction of N-glycosylation sites in B-cell receptors of anti-citrullinated protein antibody (ACPA-) expressing B cells indicate selective advantages in B-cell development.
- Brilman Elisabeth G., van der Pol Joy A., de Jong Pascal H. P., Weel Angelique E. A. M., Hazes J. M. W., Huizinga Tom W. J. & Allaart Cornelia F. (2018), Corticosteroid Bridging Strategies with Methotrexate Monotherapy in Early Rheumatoid and Undifferentiated Arthritis; A Comparison of Efficacy and Toxicity in 2 Clinical Trials, Arthritis and Rheumatology 70.
- van der Pol J. A., Brilman E. G., de Jong P. H., Weel A. E., Hazes J. M., Huizinga T. W. & Allaart C. F. (2018), CORTICOSTEROID BRIDGING STRATEGIES WITH METHOTREXATE MONOTHERAPY IN EARLY RHEUMATOID AND UNDIFFERENTIATED ARTHRITIS; A COMPARISON OF EFFICACY AND TOXICITY IN THE TREACH AND IMPROVED STUDIES, Annals of the Rheumatic Diseases 77: 65-65.
- Burgers L. E., van der Pol J. A., Huizinga T. W. J., Allaart C. F. & van der Helm-van Mil A. H. M. (2018), DOES TREATMENT STRATEGY INFLUENCE THE ABILITY TO ACHIEVE AND SUSTAIN DMARD-FREE REMISSION IN RA?; RESULTS OF A LONGITUDINAL STUDY COMPARING AN INTENSIVE DAS-STEERED TREATMENT STRATEGY WITH TREAT-TO-TARGET IN ROUTINE CARE, Annals of the Rheumatic Diseases 77: 72-72.
- Boonstra, M.; Stoop, D.F.; Huizinga, T.W.; Vlieland, T.P.V. & Vries-Bouwstra, J.K. de (2018), DON'T FORGET THE CAREGIVERS OF PATIENTS WITH SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 77: 1512-1512.
- Emery Paul, Tanaka Yoshiya, Bykerk Vivian P., Huizinga Tom W. J., Citera Gustavo, Nys Marleen, Connolly Sean E., Johnsen Alyssa & Fleischmann Roy (2018), Efficacy and Safety of Abatacept in Combination with MTX in Early, MTX-Naive, Anti-Citrullinated Protein Antibody-Positive Patients with RA: Primary and 1-Year Results from a Phase IIIb Study, Arthritis and Rheumatology 70.
- Akdemir, G.; Heimans, L.; Bergstra, S.A.; Goekoop, R.J.; Oosterhout, M. van; Groenendael, J.H.L.M. van; Peeters, A.J.; Steup-Beekman, G.M.; Lard, L.R.; Sonnaville, P.B.J. de; Grillet, B.A.M.; Huizinga, T.W.J. & Allaart, C.F. (2018), Clinical and radiological outcomes of 5-year drug-free remission-steered treatment in patients with early arthritis: IMPROVED study, Annals of the Rheumatic Diseases 77(1): 111-118.
- Brinck, R.M. ten; Moel, E.C. de; Pol, J.A. van der; Beest, S. van; Koning, A. de & Huizinga, T.W.J. (2018), Is optimising gout treatment the key to closing the mortality gap in gout patients?, Annals of the Rheumatic Diseases 77(1).
- Steenbergen, H.W. van; Silva, J.A.P. da; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2018), Preventing progression from arthralgia to arthritis: targeting the right patients, Nature Reviews Rheumatology 14(1): 32-41.
- Hermans M.P.J., Velden D. van der, Montero Cabezas J.M., Putter H., Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2017), Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies, International Journal of Cardiology 240: 20-24.
- Hermans M.P.J., Volkov M., Velden D. van der, Montero Cabezas J.M., Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2017), Anti-citrullinated protein antibodies: a marker of cardiovascular disease and mortality in patients without rheumatoid arthritis, Annals of the Rheumatic Diseases 76: A82-A82.
- Bergstra, S.A.; Chopra, A.; Saluja, M.; Vega-Morales, D.; Govind, N.; Huizinga, T.W.J. & Helm-van Mil, A. van der (2017), Evaluation of the joint distribution at disease presentation of patients with rheumatoid arthritis: a large study across continents, RMD Open 3(2).
- Brinck, R.M. ten; Steenbergen, H.W. van; Mangnus, L.; Burgers, L.E.; Reijnierse, M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2017), Functional limitations in the phase of clinically suspect arthralgia are as serious as in early clinical arthritis; a longitudinal study, RMD Open.
- Dekkers, J.S.; Verheul, M.K.; Stoop, J.N.; Liu, B.S.; Ioan-Facsinay, A.; Veelen, P.A. van; Ru, A.H. de; Janssen, G.M.C.; Hegen, M.; Rapecki, S.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2017), Breach of autoreactive B-cell tolerance by post-translationally modified foreign proteins, Annals of the Rheumatic Diseases.
- Boonstra, M.; Bakker, J.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2017), To What Extend Do Auto-Antibodies Help to Identify High-Risk Patients in Systemic Sclerosis?, Arthritis and Rheumatology 69.
- Rochelle D. Vergroesen, Linda M. Slot, Lise Hafkenscheid, Marvyn T. Koning, Ellen I.H. van der Voort, Christine A. Grooff, George Zervakis, Hendrik Veelken, Tom W.J. Huizinga, Theo Rispens, Hans U. Scherer & René E.M. Toes (2017), Introduction of N-glycosylation sites in ACPA-IgG B cells.
- Cui, J.; Diogo, D.; Stahl, E.A.; Canhao, H.; Mariette, X.; Greenberg, J.D.; Okada, Y.; Pappas, D.A.; Fulton, R.S.; Tak, P.P.; Nurmohamed, M.T.; Lee, A.; Larson, D.E.; Kurreeman, F.; Deluca, T.L.; O'Laughlin, M.; Fronick, C.C.; Fulton, L.L.; Mardis, E.R.; Horst-Bruinsma, I.E. van der; Wolbink, G.J.; Gregersen, P.K.; Kremer, J.M.; Crusius, J.B.A.; Vries, N. de; Huizinga, T.W.J.; Fonseca, J.E.; Miceli-Richard, C.; Karlson, E.W.; Coenen, M.J.H.; Barton, A.; Plenge, R.M. & Raychaudhuri, S. (2017), The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis, Arthritis and Rheumatology 69(4): 735-741.
- Derksen, V.F.A.M.; Huizinga, T.W.J. & Woude, D. van der (2017), The role of autoantibodies in the pathophysiology of rheumatoid arthritis, Seminars in Immunopathology 39(4): 437-446.
- Boeters, D.M.; Mangnus, L.; Ajeganova, S.; Lindqvist, E.; Svensson, B.; Toes, R.E.M.; Trouw, L.A.; Huizinga, T.W.J.; Berenbaum, F.; Morel, J.; Rantapaa-Dahlqvist, S. & Helm-van Mil, A.H.M. van der (2017), The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical, Arthritis Research and Therapy 19.
- Jonasdottir, H.S.; Brouwers, H.; Kwekkeboom, J.C.; Linden, H.M.J. van der; Huizinga, T.; Kloppenburg, M.; Toes, R.E.M.; Giera, M. & Ioan-Facsinay, A. (2017), Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans, Osteoarthritis and Cartilage 25(7): 1150-1160.
- Derksen, V.F.A.M.; Ajeganova, S.; Trouw, L.A.; Helm-van Mil, A.H.M. van der; Hafstrom, I.; Huizinga, T.W.J.; Toes, R.E.M.; Svensson, B. & Woude, D. van der (2017), Rheumatoid arthritis phenotype at presentation differs depending on the number of autoantibodies present, Annals of the Rheumatic Diseases 76(4).
- Meulen, P.M. van der; Barendregt, A.M.; Cuadrado, E.; Magro-Checa, C.; Steup-Beekman, G.M.; Schonenberg-Meinema, D.; Berg, J.M. van den; Li, Q.Z.; Baars, P.A.; Wouters, D.; Voskuyl, A.E.; Berge, I.R.J.M. ten; Huizinga, T.W.J. & Kuijpers, T.W. (2017), Protein array autoantibody profiles to determine diagnostic markers for neuropsychiatric systemic lupus erythematosus, Rheumatology 56(8): 1407-1416.
- Zanten, A. van; Arends, S.; Roozendaal, C.; Limburg, P.C.; Maas, F.; Trouw, L.A.; Toes, R.E.M.; Huizinga, T.W.J.; Bootsma, H. & Brouwer, E. (2017), Presence of anticitrullinated protein antibodies in a large population-based cohort from the Netherlands, Annals of the Rheumatic Diseases 76(7): 1184-1190.
- Markusse, I.M.; Meijs, J.; Boer, B. de; Bakker, J.A.; Schippers, H.P.C.; Schouffoer, A.A.; Marsan, N.A.; Kroft, L.J.M.; Ninaber, M.K.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2017), Predicting cardiopulmonary involvement in patients with systemic sclerosis: complementary value of nailfold videocapillaroscopy patterns and disease-specific autoantibodies, Rheumatology 56(7): 1081-1088.
- Huizinga, T.W.J.; Batalov, A.; Stoilov, R.; Lloyd, E.; Wagner, T.; Saurigny, D.; Souberbielle, B. & Esfandiari, E. (2017), Phase 1b randomized, double-blind study of namilumab, an anti-granulocyte macrophage colony-stimulating factor monoclonal antibody, in mild-to-moderate rheumatoid arthritis, Arthritis Research and Therapy 19.
- Eektimmerman, F.; Swen, J.J.; Bohringer, S.; Huizinga, T.W.J.; Kooloos, W.M.; Allaart, C.F. & Guchelaar, H.J. (2017), Pathway analysis to identify genetic variants associated with efficacy of adalimumab in rheumatoid arthritis, Pharmacogenomics 18(10): 945-953.
- Magro-Checa, C.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.M.; Dane, M.L.; Wee, N.J. van der; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Outcomes of neuropsychiatric events in systemic lupus erythematosus based on clinical phenotypes; prospective data from the Leiden NP SLE cohort, Lupus 26(5): 543-551.
- Hermans, M.P.J.; Velden, D. van der; Cabezas, J.M.M.; Putter, H.; Huizinga, T.W.J.; Kuiper, J.; Toes, R.E.M.; Schalij, M.J.; Jukema, J.W. & Woude, D. van der (2017), Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies, International Journal of Cardiology 240: 20-24.
- Hooge, M. de; Bruin, F. de; Beer, L. de; Bakker, P.; Berg, R. van den; Ramiro, S.; Gaalen, F. van; Fagerli, K.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Bloem, H.; Reijnierse, M. & Heijde, D. van der (2017), Is the Site of Back Pain Related to the Location of Magnetic Resonance Imaging Lesions in Patients With Chronic Back Pain? Results From the Spondyloarthritis Caught Early Cohort.
- Nieuwenhuis, W.P.; Steenbergen, H.W. van; Mangnus, L.; Newsum, E.C.; Bloem, J.L.; Huizinga, T.W.J.; Cessie, S. le; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2017), Evaluation of the diagnostic accuracy of hand and foot MRI for early Rheumatoid Arthritis, Rheumatology 56(8): 1367-1377.
- Burgers, L.E.; Allaart, C.F.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2017), Clinical Trials Aiming to Prevent Rheumatoid Arthritis Cannot Detect Prevention Without Adequate Risk Stratification: A Trial of Methotrexate Versus Placebo in Undifferentiated Arthritis as an Example, Arthritis and Rheumatology 69(5): 926-931.
- Emery, P.; Hoogstraten, H. van; Mangan, E.; Kivitz, A.; Pinheiro, G. & Huizinga, T. (2017), CLINICAL RESPONSES OF SARILUMAB BASED ON RHEUMATOID FACTOR AND ANTI- CYCLIC CITRULLINATED PEPTIDE AUTOANTIBODY STATUS IN PATIENTS WITH RHEUMATOID ARTHRITIS, Internal Medicine Journal 47: 29-30.
- Erp, S. van; Ercan, E.; Breedveld, P.; Brakenhoff, L.; Ghariq, E.; Schmid, S.; Osch, M. van; Buchem, M. van; Emmer, B.; Grond, J. van der; Wolterbeek, R.; Hommes, D.; Fidder, H.; Wee, N. van der; Huizinga, T.; Heijde, D. van der; Middelkoop, H.; Ronen, I. & Meulen-de Jong, A. van der (2017), Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue, World Journal of Gastroenterology 23(6): 1018-1029.
- Dekkers, J.S.; Verheul, M.K.; Stoop, J.N.; Liu, B.S.; Ioan-Facsinay, A.; Veelen, P.A. van; Ru, A.H. de; Janssen, G.M.C.; Hegen, M.; Rapecki, S.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2017), Breach of autoreactive B cell tolerance by post-translationally modified proteins, Annals of the Rheumatic Diseases 76(8): 1449-1457.
- Vos, I.; Mol, C. van; Trouw, L.A.; Mahler, M.; Bakker, J.A.; Offel, J.; Clerck, L. de & Huizinga, T.W. (2017), Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays, Clinical Rheumatology 36(7): 1487-1492.
- Hafkenscheid, L.; Bondt, A.; Scherer, H.U.; Huizinga, T.W.J.; Wuhrer, M.; Toes, R.E.M. & Rombouts, Y. (2017), Structural Analysis of Variable Domain Glycosylation of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Reveals the Presence of Highly Sialylated Glycans, Molecular and Cellular Proteomics 16(2): 278-287.
- Cohen, D.; Rijnink, E.C.; Nabuurs, R.J.A.; Steup-Beekman, G.M.; Versluis, M.J.; Emmer, B.J.; Zandbergen, M.; Buchem, M.A. van; Allaart, C.F.; Wolterbeek, R.; Bruijn, J.A.; Duinen, S.G. van; Huizinga, T.W.J. & Bajema, I.M. (2017), Brain histopathology in patients with systemic lupus erythematosus: identification of lesions associated with clinical neuropsychiatric lupus syndromes and the role of complement, Rheumatology 56(1): 77-86.
- Akdemir, G.; Markusse, I.M.; Goekoop-Ruiterman, Y.P.M.; Steup-Beekman, G.M.; Grillet, B.A.M.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2017), Rheumatologists' adherence to a disease activity score steered treatment protocol in early arthritis patients is less if the target is remission, Clinical Rheumatology 36(2): 317-326.
- Stomp, W.; Krabben, A.; Heijde, D. van der; Huizinga, T.W.J.; Bloem, J.L.; Helm-van Mil, A.H.M. van der & Reijnierse, M. (2017), Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema? (vol 24, pg 2614, 2014 ), European Radiology 27(3): 1331-1332.
- Magro-Checa, C.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.M.; Dane, M.L.; Wee, N.J. van der; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Outcomes of neuropsychiatric events in systemic lupus erythematosus based on clinical phenotypes; prospective data from the Leiden NP SLE cohort, Lupus.
- Magro-Checa, C.; Zirkzee, E.J.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.; Wee, N.J. van der; Huisman, M.V.; Eikenboom, J.; Kruyt, N.D.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort, Rheumatology.
- Dekkers, J.S.; Schoones, J.W.; Huizinga, T.W.; Toes, R.E. & Helm-van Mil, A.H. van der (2017), Possibilities for preventive treatment in rheumatoid arthritis? Lessons from experimental animal models of arthritis: a systematic literature review and meta-analysis, Annals of the Rheumatic Diseases 76(2): 458-467.
- Ajeganova, S.; Steenbergen, H.W. van; Verheul, M.K.; Forslind, K.; Hafstrom, I.; Toes, R.E.M.; Huizinga, T.W.J.; Svensson, B.; Trouw, L.A. & Helm-van Mil, A.H.M. van der (2017), The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis: a study exploring replication and the added value to ACPA and rheumatoid factor, Annals of the Rheumatic Diseases 76(1): 112-118.
- Merriman, T.R.; Cadzow, M.; Merriman, M.E.; Phipps-Green, A.; Topless, R.; Abhishek, A.; Andres, M.; Bradbury, L.A.; Buchanan, R.; Cremin, K.; Guzman, E. de; Zoysa, J. de; Doherty, M.; Hill, C.; Huizinga, T.W.J.; Jansen, T.; Janssen, M.; Joosten, L.A.B.; Kurreeman, F.; Lester, S.; Liote, F.; Macartney-Coxson, D.; Matsuo, H.; McCarthy, G.M.; McCormick, S.; Murphy, R.; Pavelka, K.; Perez-Ruiz, F.; Puig, J.; Radstake, T.R.D.J.; Riches, P.; Rischmueller, M.; Roddy, E.; Smith, M.; Stahl, E.A.; Stiburkova, B.; Stubbs, R.; Tausche, A.K.; Torres, R.; Walker, R.; Yamamoto, K.; Brown, M.A.; Choi, H.K.; Dalbeth, N.; Miner, J.N.; So, A.; Stamp, L.K. & Major, T. (2017), A Genome-Wide Association Study of Gout in People of European Ancestry, Arthritis and Rheumatology 69.
- Merriman, T.R.; Cadzow, M.; Merriman, M.; Phipps-Green, A.; Topless, R.; Abhishek, A.; Andres, M.; Bradbury, L.; Buchanan, R.; Cremin, K.; Guzman, E. de; Zoysa, J. de; Doherty, M.; Hill, C.; Huizinga, T.; Jansen, T.; Janssen, M.; Joosten, L.; Kurreeman, F.; Lester, S.; Liote, F.; Macartney-Coxson, D.; Matsuo, H.; McCarthy, G.; McCormick, S.; Murphy, R.; Pavelka, K.; Perez-Ruiz, F.; Puig, J.; Radstake, T.; Riches, P.; Rischmueller, M.; Roddy, E.; Smith, M.; Stahl, E.; Stiburkova, B.; Stubbs, R.; Tausche, A.K.; Torres, R.; Walker, R.; Yamamoto, K.; Brown, M.; Choi, H.; Dalbeth, N.; So, A.; Stamp, L. & Flynn, T. (2017), A GENOME-WIDE ASSOCIATION STUDY OF GOUT IN PEOPLE OF EUROPEAN ANCESTRY, Annals of the Rheumatic Diseases 76: 383-383.
- Kremer, J.; Huizinga, T.W.J.; Chen, L.; Saifan, C.G.; Issa, M.; Witt, S.L.; Walls, C.D. & Torre, I. de la (2017), ANALYSIS OF NEUTROPHILS, LYMPHOCYTES, AND PLATELETS IN POOLED PHASE 2 AND PHASE 3 STUDIES OF BARICITINIB FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 76: 512-512.
- Moller, B.; Scholz, G.; Dougados, M.; Huizinga, T.; Villiger, P.M. & Finckh, A. (2017), ANEMIA IS A BETTER PREDICTOR FOR RADIOGRAPHIC DAMAGE IN RHEUMATOID ARTHRITIS THAN DAS28 WHEN DETERMINED BEFORE START OF TOCILIZUMAB-TREATMENT - A SECONDARY ANALYSIS FROM THE ACT-RAY TRIAL, Annals of the Rheumatic Diseases 76: 569-569.
- Hermans, M.P.J.; Volkov, M.; Velden, D. van der; Cabezas, J.M.M.; Huizinga, T.W.J.; Kuiper, J.; Toes, R.E.M.; Schalij, M.J.; Jukema, J.W. & Woude, D. van der (2017), ANTI-CITRULLINATED PROTEIN ANTIBODIES: A MARKER OF CARDIOVASCULAR DISEASE AND MORTALITY IN PATIENTS WITHOUT RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 76: A82-A82.
- Takata, M.; Pachera, E.; Kozlova, A.; Jungel, A.; Messemaker, T.; Vries-Bouwstra, J. de; Huizinga, T.W.J.; Kurreeman, F. & Distler, O. (2017), Antisense Long Noncoding RNA HAND2-AS1 and OTUD6B-AS1 Have Important Roles in the Pathogenesis of Systemic Sclerosis, Arthritis and Rheumatology 69.
- Messemaker, T.; Chadli, L.; Cal, G.; Goelela, V.; Boonstra, M.; Dorjee, A.; Andersen, S.; Mikkers, H.; Huizinga, T.; Li, Z.; Distler, O.; Whitfield, M.; Toes, R.; Aarbiou, J.; Groot, J. de; Vries-Bouwstra, J. de & Kurreeman, F. (2017), ANTISENSE LONG NONCODING RNAS ARE DEREGULATED IN SKIN TISSUE OF SSC PATIENTS, Annals of the Rheumatic Diseases 76: 621-621.
- Messemaker, T.; Chadli, L.; Goelela, V.; Boonstra, M.; Dorjee, A.; Andersen, S.; Mikkers, H.; Distler, O.; Huizinga, T.; Li, Z.H.; Cai, G.S.; Whitfield, M.; Toes, R.; Aarbiou, J.; Groot, J. de; Vries-Bouwstra, J. de & Kurreeman, F. (2017), ANTISENSE LONG NONCODING RNAS ARE DEREGULATED IN SKIN TISSUE OF SSC PATIENTS, Annals of the Rheumatic Diseases 76: A56-A56.
- Genovese, M.C.; Hoogstraten, H. van; Kampman, W.; Jayawardena, S. & Huizinga, T.W. (2017), ASSOCIATION BETWEEN CLINICAL AND RADIOGRAPHIC RESPONSES, AND PHYSICAL FUNCTION IN A PHASE 3 STUDY OF SARILUMAB PLUS METHOTREXATE IN PATIENTS WITH ACTIVE, MODERATE-TO-SEVERE RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 76: 576-577.
- Jansen, D.; Emery, P.; Smolen, J.; Westhovens, R.; Bars, M. le; Connolly, S.; Ye, J.; Toes, R. & Huizinga, T. (2017), ASSOCIATION BETWEEN CONVERSION TO ACPA/RF SERONEGATIVE STATUS AND CLINICAL OUTCOMES FOLLOWING TREATMENT WITH ABATACEPT IN COMBINATION WITH METHOTREXATE COMPARED WITH METHOTREXATE ALONE IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS AND POOR PROGNOSTIC INDICATORS, Annals of the Rheumatic Diseases 76: 566-566.
- Segurado, R.; Shields, D.; Knevel, R.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J. & Wilson, A.G. (2017), Association of a Non-Synonymous, Loss-of-Function, Variant in NOD2 with Reduced Tissue Damage in ACPA plus Ve RA, Arthritis and Rheumatology 69.
- Hegedus, J.H. von; Heijink, M.; Huizinga, T.; Kloppenburg, M.; Giera, M.; Toes, R. & Ioan-Facsinay, A. (2017), A TEMPORAL SWITCH TOWARDS A MORE RESOLVINGCHRONIC TOLL-LIKE RECEPTOR SIGNALLING INDUCES LIPID PROFILE IN MONOCYTE-DERIVED MACROPHAGES RECEPTOR SIGNALLING INDUCES A TEMPORAL SWITCH TOWARDS A MORE RESOLVING LIPID PROFILE IN MONOCYTE-DERIVED MACROPHAGES, Osteoarthritis and Cartilage 25: S170-S171.
- Boonstra, M.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2017), Auto-antibodies and cancer in systemic sclerosis, Autoimmunity Reviews 16(8): 883-884.
- Vergroesen, R.D.; Slot, L.; Hafkenscheid, L.; Koning, M.T.; Voort, E.I.H. van der; Grooff, C.A.; Zervakis, G.; Huizinga, T.W.J.; Rispens, T.; Veelken, H.; Toes, R.E.M. & Scherer, H.U. (2017), B Cell Receptor Sequencing of Anti-Citrullinated Protein Antibody Expressing B Cells Indicates a Selective Advantage for the Introduction of N-Glycosylation Sites during Somatic Hypermutation, Arthritis and Rheumatology 69.
- Ahmad, H.; Baker, J.; Ostergaard, M.; Emery, P.; Huizinga, T.; Ye, J.; Banerjee, S. & Conaghan, P. (2017), BOTH MRI AND HAQ-DI CAN PREDICT RELAPSES FOLLOWING ALL TREATMENT WITHDRAWAL IN MTX-NAIVE PATIENTS WITH RA IN REMISSION AFTER 12 MONTHS OF ABATACEPT THERAPY IN THE AVERT TRIAL, Annals of the Rheumatic Diseases 76: 240-240.
- Dekkers, J.; Verheul, M.; Stoop, J.; Liu, B.; Ioan-Facsinay, A.; Veelen, P. van; Ru, A. de; Janssen, G.; Hegen, M.; Rapecki, S.; Huizinga, T.; Trouw, L. & Toes, R. (2017), BREACH OF AUTOREACTIVE B-CELL TOLERANCE BY, Annals of the Rheumatic Diseases 76: 778-779.
- Derksen, V.F.A.M.; Moel, E.C. de; Trouw, L.A.; Goekoop, R.J.; Speyer, I.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2017), BREADTH OF BASELINE AUTOANTIBODY PROFILE AND TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 76: 1076-1076.
- Hegedus, J.H. von; Madari, Q.S.R.; Muller, P.C.E.H.; Kloppenburg, M.; Toes, R.E.M.; Giera, M.; Huizinga, T.W.J.; Cate, R. ten & Ioan-Facsinay, A. (2017), Characterisation of Lipid Mediator Profile and Immune Cells in Synovial Fluid of Juvenile Idiopathic Arthritis, Arthritis and Rheumatology 69.
- Emery, P.; Hoogstraten, H. van; Mangan, E.K.; Adelsberg, J. van; Fan, C.P.; Kivitz, A.; Pinheiro, G.D.C. & Huizinga, T.W. (2017), CLINICAL RESPONSES OF SARILUMAB BASED ON RHEUMATOID FACTOR AND ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY STATUS IN PATIENTS WITH RHEUMATOID ARTHRITIS, Rheumatology 56: 140-141.
- Burgers, L.E.; Steenbergen, H.W. van; Brinck, R.M. ten; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2017), Differences in the symptomatic phase preceding ACPA-positive and ACPA-negative RA: a longitudinal study in arthralgia during progression to clinical arthritis, Annals of the Rheumatic Diseases 76(10): 1751-1754.
- Damman, W.; Liu, R.N.; Kroon, F.P.B.; Reijnierse, M.; Huizinga, T.W.J.; Rosendaal, F.R. & Kloppenburg, M. (2017), Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort, Journal of Rheumatology 44(11): 1659-1666.
- Boonstra, M.; Bakker, J.A.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W. & Vries-Bouwstra, J.K. de (2017), DOES A SYSTEMIC SCLEROSIS PATIENT'S CLINICAL PHENOTYPE DEMONSTRATE HIS AUTOANTIBODY STATUS?, Annals of the Rheumatic Diseases 76: 903-904.
- Edwards, C.J.; Fautrel, B.; Schulze-Koops, H.; Huizinga, T.W.J. & Kruger, K. (2017), Dosing down with biologic therapies: a systematic review and clinicians' perspective, Rheumatology 56(11): 1847-1856.
- Genovese, M.C.; Mangan, E.K.; Kimura, T.; Iglesias-Rodriguez, M. & Huizinga, T.W.J. (2017), Duration of Response in a Phase 3 Study of Sarilumab Plus Methotrexate in Patients with Active, Moderate-to-Severe Rheumatoid Arthritis, Arthritis and Rheumatology 69.
- Kroon, F.P.; Wittoek, R.; Verbruggen, G.; Haugen, I.K.; Huizinga, T.W. & Kloppenburg, M. (2017), EFFECT OF ETANERCEPT ON SYNOVITIS AND BONE MARROW LESIONS IN EROSIVE HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 25: S39-S40.
- Genovese, M.C.; Fleischmann, R.; Mangan, E.K.; Adelsberg, J. van; Iglesias-Rodriguez, M.; Fan, C.P. & Huizinga, T.W. (2017), EFFICACY AND SAFETY OF SARILUMAB IN SUBGROUPS OF PATIENTS WITH RHEUMATOID ARTHRITIS FROM 2 PHASE 3 STUDIES, Rheumatology 56: 137-138.
- Smolen, J.S.; Landewe, R.; Bijlsma, J.; Burmester, G.; Chatzidionysiou, K.; Dougados, M.; Nam, J.; Ramiro, S.; Voshaar, M.; Vollenhoven, R. van; Aletaha, D.; Aringer, M.; Boers, M.; Buckley, C.D.; Buttgereit, F.; Bykerk, V.; Cardiel, M.; Combe, B.; Cutolo, M.; Eijk-Hustings, Y. van; Emery, P.; Finckh, A.; Gabay, C.; Gomez-Reino, J.; Gossec, L.; Gottenberg, J.E.; Hazes, J.M.W.; Huizinga, T.; Jani, M.; Karateev, D.; Kouloumas, M.; Kvien, T.; Li, Z.G.; Mariette, X.; McInnes, I.; Mysler, E.; Nash, P.; Pavelka, K.; Poor, G.; Richez, C.; Riel, P. van; Rubbert-Roth, A.; Saag, K.; Silva, J. da; Stamm, T.; Takeuchi, T.; Westhovens, R.; Wit, M. de & Heijde, D. van der (2017), EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update, Annals of the Rheumatic Diseases 76(6): 960-977.
- Boer, A.C.; Burgers, L.E.; Mangnus, L.; Brinck, R.M. ten; Nieuwenhuis, W.P.; Steenbergen, H.W. van; Reijnierse, M.; Huizinga, T.W. & Mil, A.H.V. van (2017), EVALUATION OF THE ACCURACY OF HAND AND FOOT MRI IN THE EARLY IDENTIFICATION OF RA: USING THE PREVALENCE OF LOW-GRADED INFLAMMATION IN THE SYMPTOM-FREE POPULATION AS REFERENCE REDUCES FALSE-POSITIVE MRI RESULTS, Annals of the Rheumatic Diseases 76: 473-474.
- Westra, H.J.; Martinez-Bonet, M.; Onengut, S.; Lee, A.; Luo, Y.; Teslovich, N.; Worthington, J.; Martin, J.; Huizinga, T.W.J.; Klareskog, L.; Dahlqvist, S.R.; Chen, W.M.; Quinlan, A.; Todd, J.; Eyre, S.; Nigrovic, P.; Gregersen, P.; Rich, S. & Raychaudhuri, S. (2017), Fine-Mapping Identifies Causal Variants for RA and T1D in DNASE1L3, Sirpg, MEG3, TNFAIP3 and CD28/CTLA4 Loc, Arthritis and Rheumatology 69.
- Knevel, R.; Huizinga, T.W.J. & Kurreeman, F. (2017), Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis, Rheumatic Disease Clinics of North America 43(3): 347-+.
- Curtis, J.R.; Brahe, C.H.; Ostergaard, M.; Hetland, M.L.; Hambardzumyan, K.; Saevarsdottir, S.; Wang, X.B.; Sasso, E.H. & Huizinga, T.W.J. (2017), High Multi-Biomarker Disease Activity Score Is Associated with High Risk of Radiographic Progression in Six Cohorts, Arthritis and Rheumatology 69.
- Curtis, J.R.; Brahe, C.H.; Ostergaard, M.; Hetland, M.L.; Hambardzumyan, K.; Saevarsdottir, S.; Wang, X.; Sasso, E.H. & Huizinga, T.W. (2017), HIGH MULTI-BIOMARKER DISEASE ACTIVITY SCORE IS ASSOCIATED WITH HIGH RISK OF RADIOGRAPHIC PROGRESSION IN SIX STUDIES, Annals of the Rheumatic Diseases 76: 234-235.
- Stamm, T.A.; Machold, K.; Aletaha, D.; Alasti, F.; Lipsky, P.; Pisetsky, D.; Landewe, R.; Heijde, D. van der; Sepriano, A.; Aringer, M.; Boumpas, D.; Burmester, G.; Cutolo, M.; Ebener, W.; Graninger, W.; Huizinga, T.; Schett, G.; Schulze-Koops, H.; Tak, P.P.; Breedveld, F. & Smolen, J. (2017), INDUCTION OF SUSTAINED REMISSION IN EARLY INFLAMMATORY ARTHRITIS WITH THE COMBINATION OF INFLIXIMAB PLUS METHOTREXATE, METHOTREXATE ALONE OR PLACEBO: THE DINORA TRIAL, Annals of the Rheumatic Diseases 76: 560-560.
- Messemaker, T.; Mikkers, H.M.M.; Huizinga, T.W.; Toes, R.E.M.; Helm-van Mil, A.H.M. van der & Kurreeman, F. (2017), Inflammatory genes TNF alpha and IL6 display no signs of increased H3K4me3 in circulating monocytes from untreated rheumatoid arthritis patients, Genes and Immunity 18(3): 191-196.
- Moel, E. de; Derksen, V.; Trouw, L.A.; Bang, H.; Goekoop-Ruiterman, Y.P.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2017), In RA, Becoming Seronegative over the 1st Year of DMARD Treatment Does Not Improve Chances of Drug-Free Remission in the Long-Term, Arthritis and Rheumatology 69.
- Boeters, D.; Mangnus, L.; Ajeganova, S.; Lindqvist, E.; Svensson, B.; Toes, R.; Trouw, L.; Huizinga, T.; Berenbaum, F.; Morel, J.; Rantapaa-Dahlqvist, S. & Helm-van Mil, A. van der (2017), IN THE ELDERLY ACPA-NEGATIVE RA IS MORE PREVALENT THAN ACPA-POSITIVE RA WHILE THE COMPOSITION OF THE ACPA-RESPONSE APPEARS IDENTICAL, Annals of the Rheumatic Diseases 76: 1050-1051.
- Volkov, M.; Dekkers, J.; Loos, B.G.; Bizzarro, S.; Huizinga, T.W.J.; Praetorius, H.A.; Toes, R.E.M. & Woude, D. van der (2017), Is Leukotoxin_A Produced By Aggregatibacter Actynomycetemcomitans Important for Initiating Autoimmune Responses Underlying Rheumatoid Arthritis?, Arthritis & Rheumatology 69.
- Messemaker, T.; Suurmond, J.; Habets, K.L.; Heijink, M.; Schonkeren, J.J.; Dorjee, A.; Giera, M.; Huizinga, T.W.; Toes, R.E. & Kurreeman, F. (2017), MAST CELLS ARE REPROGRAMMED THROUGH REPEATED TRIGGERING, Annals of the Rheumatic Diseases 76: A37-A38.
- Messemaker, T.; Suurmond, J.; Habets, K.; Heijink, M.; Schonkeren, J.; Dorjee, A.; Giera, M.; Huizinga, T.; Toes, R. & Kurreeman, F. (2017), MAST CELLS SHOW A REPROGRAMMED TRANSCRIPTIONAL SIGNATURE FOLLOWING REPEATED IGG STIMULATIONS, Annals of the Rheumatic Diseases 76: 202-203.
- Scally, S.W.; Law, S.C.; Ting, Y.T.; Heemst, J. van; Sokolove, J.; Deutsch, A.J.; Clemens, E.B.; Moustakas, A.K.; Papadopoulos, G.K.; Woude, D. van der; Smolik, I.; Hitchon, C.A.; Robinson, D.B.; Ferucci, E.D.; Bernstein, C.N.; Meng, X.B.; Anaparti, V.; Huizinga, T.; Kedzierska, K.; Reid, H.H.; Raychaudhuri, S.; Toes, R.E.; Rossjohn, J.; El-Gabalawy, H. & Thomas, R. (2017), Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis, Annals of the Rheumatic Diseases 76(11): 1915-1923.
- Monahan, R.C.; Beaart-van de Voorde, L.J.J.; Steup-Beekman, G.M.; Magro-Checa, C.; Huizinga, T.W.J.; Hoekman, J. & Kaptein, A.A. (2017), Neuropsychiatric symptoms in systemic lupus erythematosus: impact on quality of life, Lupus 26(12): 1252-1259.
- Knevel, R.; Terao, C.; Cui, J.; Slowikowski, K.; Huizinga, T.W.J.; Karlson, E. & Raychaudhuri, S. (2017), Optimizing Precision Medicine By Using Genetics to Assign Diagnostic Prior Probabilities to Patients with Synovitis, Arthritis and Rheumatology 69.
- Knevel, R.; Raychaudhuri, S.; Liao, K. & Huizinga, T.W. (2017), PRECISE AND SIMPLE ALGORITHM TO IDENTIFY RA CASES IN ELECTRONIC MEDICAL RECORDS, Annals of the Rheumatic Diseases 76: 445-446.
- Schordan, E.; Mehdi, M.; Danilin, S.; Coq, M.; Schumacher, M.; Huizinga, T. & Firat, H. (2017), RABIOPRED, AN INNOVATIVE THERAGNOSTIC TOOL FOR PRECISION MEDICINE IN RHEUMATOID ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 76: 1463-1463.
- Kloppenburg, M.; Ramonda, R.; Kwok, W.Y.; Bobacz, K.; Elewaut, D.; Frallonardo, P.; Huizinga, T.W.; Kroon, F.P.; Smolen, J.; Cruyssen, B.V.; Wolterbeek, R.; Punzi, L.; Verbruggen, G. & Wittoek, R. (2017), RANDOMISED, PLACEBO-CONTROLLED TRIAL TO EVALUATE CLINICAL EFFICACY AND STRUCTURE MODIFYING PROPERTIES OF SUBCUTANEOUS ETANERCEPT IN PATIENTS WITH EROSIVE INFLAMMATORY HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 25: S8-S8.
- Pol, J.A. van der; Akdemir, G.; Broek, M. van den; Dirven, L.; Kerstens, P.; Lems, W.F.; Markusse, I.M.; Huizinga, T.W. & Allaart, C.F. (2017), REPAIR OF JOINT DAMAGE IN NEWLY DIAGNOSED RHEUMATOID ARTHRITIS PATIENTS OCCURS BUT DOES NOT RELATE TO PREVIOUS SUPPRESSION OF INFLAMMATION; AN 8-YEARS SUB ANALYSIS IN THE BEST-COHORT, Annals of the Rheumatic Diseases 76: 516-516.
- Pol, J.A. van der; Akdemir, G.; Broek, M. van den; Dirven, L.; Kerstens, P.J.S.M.; Lems, W.F.; Markusse, I.M.; Allaart, C.F. & Huizinga, T.W.J. (2017), Repair of Joint Damage Is Rare in Newly Diagnosed Rheumatoid Arthritis Patients and Appears Not to Relate to Previous Suppression of Inflammation, Arthritis and Rheumatology 69.
- Bergstra, S.A.; Landewe, R.B.M.; Huizinga, T.W.J. & Allaart, C.F. (2017), Rheumatoid arthritis patients with continued low disease activity have similar outcomes over 10 years, regardless of initial therapy, Rheumatology 56(10): 1721-1728.
- Bergstra, S.A.; Landewe, R.B.; Huizinga, T.W. & Allaart, C.F. (2017), RHEUMATOID ARTHRITIS PATIENTS WITH CONTINUED LOW DISEASE ACTIVITY HAVE SIMILAR OUTCOMES OVER 10 YEARS, REGARDLESS OF INITIAL THERAPY, Annals of the Rheumatic Diseases 76: 160-160.
- Kraaij, T.; Kamerling, S.W.; Bakker, J.A.; Huizinga, T.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K. (2017), SIGNIFICANT REDUCTIONS OF PATHOGENIC AUTOANTIBODIES BY SYNERGETIC RITUXIMAB AND BELIMUMAB TREATMENT EFFECTIVELY INHIBITS NEUTROPHIL EXTRACELLULAR TRAPS IN SEVERE, REFRACTORY SLE - THE SYNBIOSE STUDY, Annals of the Rheumatic Diseases 76: 181-181.
- Bergstra, S.A.; Allaart, C.F.; Berg, R. van den; Chopra, A.; Govind, N.; Huizinga, T.W.J. & Landewe, R.B.M. (2017), Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis, Arthritis Research and Therapy 19.
- Ajeganova, S. & Huizinga, T. (2017), Sustained remission in rheumatoid arthritis: latest evidence and clinical considerations, Therapeutic Advances in Musculoskeletal Disease 9(10): 249-262.
- Kraaij, T.; Kamerling, S.W.A.; Rooij, E.N.M. de; Daele, P.L. van; Bredewold, O.W.; Bakker, J.A.; Bajema, I.; Scherer, H.U.; Toes, R.E.M.; Huizinga, T.W.J.; Rabelink, T.; Kooten, C. van & Teng, Y.K.O. (2017), Synergetic B-Cell Immunomodulation with Rituximab and Belimumab Combination Treatment in Severe, Refractory SLE, Arthritis and Rheumatology 69.
- Kraaij, T.; Kamerling, S.W.; Rooij, E. de; Daele, P.L. van; Bajema, I.; Bredewold, O.W.; Huizinga, T.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K. (2017), SYNERGETIC B-CELL IMMUNOMODULATION WITH RITUXIMAB AND BELIMUMAB IS CLINICALLY EFFECTIVE IN SEVERE AND REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS - THE SYNBIOSE PROOF-OF-CONCEPT STUDY, Annals of the Rheumatic Diseases 76: 871-871.
- Khidir, S.J.H.; Boonstra, M.; Boerrigter, G.W.M.; Voogt-van der Harst, E.M.; Bergstra, S.A.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2017), THE COURSE OF MOUTH OPENING AND ITS RELATIONSHIP WITH DISEASE CHARACTERISTICS, GLOBAL FUNCTIONING, HEALTH-RELATED QUALITY OF LIFE AND MOUTH HANDICAP IN PATIENTS WITH SYSTEMIC SCLEROSIS, Annals of the Rheumatic Diseases 76: 907-907.
- Trouw, L.; Connolly, S.; Johnsen, A.; Ye, J.; Maldonado, M.; Toes, R. & Huizinga, T. (2017), THE IMPACT OF THERAPY ON ANTI-CARBAMYLATED PROTEIN ANTIBODY ISOTYPES AND SEROSTATUS IN PATIENTS WITH EARLY RA TREATED WITH ABATACEPT AND METHOTREXATE, Annals of the Rheumatic Diseases 76: 1135-1135.
- Trouw, L.A.; Connolly, S.E.; Johnsen, A.; Ye, J.; Maldonado, M.A.; Toes, R.E.M. & Huizinga, T.W.J. (2017), The Impact of Therapy on Anti-Carbamylated Protein Antibody Isotypes and Serostatus in Patients with Early RA Treated with Abatacept and MTX, Arthritis and Rheumatology 69.
- Delft, M.A.M. van; Verheul, M.K.; Burgers, L.E.; Derksen, V.F.A.M.; Helm-van Mil, A.H.M. van der; Woude, D. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2017), The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients, Arthritis Research and Therapy 19.
- Moel, E. de; Derksen, V.; Trouw, L.A.; Bang, H.; Goekoop, R.J.; Speyer, I.; Huizinga, T.W.J.; Allaart, C.F.; Toes, R.E.M. & Woude, D. van der (2017), The Presence of a Large Number of Autoantibodies at Baseline Is Favourable for Early Treatment Response but Unfavourable for Drug-Free Remission in RA Patients, Arthritis and Rheumatology 69.
- Boonstra, M.; Bakker, J.; Ninaber, M.K.; Marsan, N.A.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2017), To What Extend Do Auto-Antibodies Help to Identify High-Risk Patients in Systemic Sclerosis?, Arthritis and Rheumatology 69.
- Boer, A.C.; Burgers, L.E.; Mangnus, L.; Brinck, R.M. ten; Nieuwenhuis, W.P.; Steenbergen, H.W. van; Reijnierse, M.; Huizinga, T.W.J. & Mil, A.H.M.V. van (2017), Using a reference when defining an abnormal MRI reduces false-positive MRI results-a longitudinal study in two cohorts at risk for rheumatoid arthritis, Rheumatology 56(10): 1700-1706.
- Bergstra, S.A.; Allaart, C.F.; Berg, R. van den; Chopra, A.; Govind, N.; Huizinga, T.W.; Landewe, R.B. & METEOR Working Grp (2017), SIMILAR SHORT TERM CLINICAL RESPONSE TO INITIAL TREATMENT WITH HIGH VERSUS LOW DOSE METHOTREXATE IN MONO- AND COMBINATION THERAPY IN EARLY RHEUMATOID ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 76: 146-146.
- Magro-Checa, C.; Zirkzee, E.J.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.; Wee, N.J. van der; Huisman, M.V.; Eikenboom, J.; Kruyt, N.D.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort, Rheumatology 56(10): 1676-1683.
- (2017), Inflammatory genes TNFα and IL6 display no signs of increased H3K4me3 in circulating monocytes from untreated rheumatoid arthritis patients, Genes and Immunity.
- Velden D. van der, Lagraauw H.M., Wezel A., Launay P., Kuiper J., Huizinga T.W.J., Toes R.E.M., Bot I. & Stoop J.N. (2016), Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile, Arthritis Research & Therapy 18(1): 138.
- Hermans M., Velden D. van der, Huizinga T.W.J., Kuiper J., Toes R.E.M., Schalij M.J., Jukema J.W. & Woude D. van der (2016), Association Between Presence of a Cardiac Intensivist and Mortality in an Adult Cardiac Care Unit, Journal of the American College of Cardiology 67(13): 2322-2322.
- Woude D. van der, Hermans M.P., Velden D. van der, Trouw L.A., Huizinga T.W.J., Kuiper J., Schalij M.J., Jukema J.W. & Toes R.E. (2016), Anti-Citrullinated Protein Antibodies in Patients with Cardiovascular Disease without RA, Annals of the Rheumatic Diseases 75: 926-926.
- Bergstra, S.A.; Machado, P.M.; Berg, R. van den; Landewe, R.B.M. & Huizinga, T.W.J. (2016), Ten years of METEOR (an international rheumatoid arthritis registry): development, research opportunities and future perspectives, Clinical and Experimental Rheumatology 34(5): S87-S90.
- Bergstra, S.A.; Machado, P.M.; Berg, R. van den; Landewe, R.B.M. & Huizinga, T.W.J. (2016), Ten years of METEOR (an international rheumatoid arthritis registry): development, research opportunities and future perspectives, Clinical and Experimental Rheumatology 34 suupl 101(5).
- Bergstra, S.A.; Berg, R. van den; Chopra, A.; Silva, J.A.P. da; Vega-Morales, D.; Govind, N.; Huizinga, T.W.J. & Landewe, R.B.M. (2016), Differences Between Patient and Physician Global Assessment on Rheumatoid Arthritis Disease Activity Status in High and Lower Income Countries Contribute to Inequity, Arthritis and Rheumatology 68.
- Gvozdenovic, E.; Wolterbeek, R.; Heijde, D. van der; Huizinga, T.; Allaart, C. & Landewe, R. (2016), DAS steered therapy in clinical practice; cross-sectional results from the METEOR database, BMC Musculoskeletal Disorders 17.
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- de Jong AJ, de Lange-Brokaar BJ, Klein-Wieringa IR, Heijink M, Hoekstra A, Everts B, Kwekkeboom JC, Berkers CR, Giera M, Huizinga TW, Kloppenburg M, Toes RE & Ioan-Facsinay A (2016), SYNOVIAL CD4+T CELLS ASSOCIATE WITH PAIN IN OSTEOARTHRITIS: IS THERE A ROLE FOR FATTY ACIDS?, Osteoarthritis and Cartilage 24: S321-S321.
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- Akdemir, G.; Markusse, I.M.; Goekoop-Ruiterman, Y.P.; Harbers, J.B.; Oosterhout, M. van; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2016), Assessment of Two Different DAS Treatment Targets in Early Active Rheumatoid Arthritis Patients, Arthritis and Rheumatology 68.
- Hafkenscheid, L.; Scherer, H.U.; Huizinga, T.W.J.; Wuhrer, M.; Rombouts, Y. & Toes, R.E.M. (2016), Extensive glycosylation of Anti-Citrullinated Protein Antibodies variable domains in rheumatoid arthritis, Glycobiology 26(12): 1481-1482.
- Schaarenburg, R.A. van; Magro-Checa, C.; Bakker, J.A.; Teng, Y.K.O.; Bajema, I.M.; Huizinga, T.W.; Steup-Beekman, G.M. & Trouw, L.A. (2016), C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus, Frontiers in Immunology 7.
- César Magro-Checa, Rosanne A Schaarenburg, Hannelore J L Beaart, Tom W J Huizinga, Gerda M Steup-Beekman & Leendert A Trouw (2016), Complement levels and anti-C1q autoantibodies in patients with neuropsychiatric systemic lupus erythematosus, Lupus.
- Ercan, E.; Magro-Checa, C.; Valabregue, R.; Branzoli, F.; Wood, E.T.; Steup-Beekman, G.M.; Webb, A.G.; Huizinga, T.W.J.; Buchem, M.A. van & Ronen, I. (2016), Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites, Brain.
- Jonasdottir, H.; Brouwers, H.; Attur, M.; Kwekkeboom, J.; Samuels, J.; Strauss, E.; Linden-van der Zwaag, E. van der; Huizinga, T.W.J.; Kloppenburg, M.; Toes, R.E.M.; Giera, M.; Abramson, S.B. & Ioan-Facsinay, A. (2016), Targeted Lipidomics Reveals Incomplete Activation of Resolution Pathways in Knee Osteoarthritis, Arthritis and Rheumatology 68.
- Kroon, F.; Wittoek, R.; Kwok, W.Y.; Bobacz, K.; Elewaut, D.; Favero, M.; Huizinga, T.; Smolen, J.; Vander Cruyssen, B.; Wolterbeek, R.; Punzi, L.; Verbruggen, G.; Kloppenburg, M. & Ramonda, R. (2016), Effect of Etanercept on Several Soluble Biomarkers in a Randomized Controlled Trial of Patients with Erosive Hand Osteoarthritis, Arthritis and Rheumatology 68.
- Heimans, L.; Akdemir, G.; Wevers-de Boer, K.V.C.; Goekoop-Ruiterman, Y.P.; Molenaar, E.T.; Groenendael, J.H.L.M. van; Peeters, A.J.; Steup-Beekman, G.M.; Lard, L.R.; Sonnaville, P.B.J. de; Grillet, B.A.M.; Huizinga, T.W.J. & Allaart, C.F. (2016), Two-year results of disease activity score (DAS)-remission-steered treatment strategies aiming at drug-free remission in early arthritis patients (the IMPROVED-study).
- S. Ajeganova, H.W. van Steenbergen, M.K. Verheul, K. Forslind, I. Hafstrom, R.E.M. Toes, T.W.J. Huizinga, B. Svensson, L.A. Trouw & A.H.M. van der Helm-van Mil (2016), The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis; a study exploring replication and clinical usefulness, Annals of the Rheumatic Diseases.
- Bergstra, S.; Berg, R. van den; Bijkerk, C.; Gerards, A.; Goekoop, R.; Kerstens, P.; Lems, W.; Huizinga, T.; Landewe, R. & Allaart, C. (2015), EROSIONS IN THE FOOT AT BASELINE ARE PREDICTIVE OF ORTHOPEDIC SHOES USE AFTER 10 YEARS OF TREAT TO TARGET THERAPY - RESULTS FROM THE BEST STUDY, Annals of the Rheumatic Diseases 74: 438-439.
- Derksen, V.; Helm-van Mil, A. van der; Huizinga, T.; Toes, R. & Woude, D. van der (2015), THE NUMBER OF DIFFERENT AUTOANTIBODIES IS ASSOCIATED WITH PHENOTYPIC CHARACTERISTICS AT PRESENTATION IN PATIENTS WITH RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 74: 689-690.
- Rivellese, F.; Suurmond, J.; Habets, K.; Dorjee, A.L.; Paulis, A. de; Marone, G.; Pitzalis, C.; Huizinga, T.W. & Toes, R.E. (2015), HUMAN MAST CELLS STIMULATED WITH IL-33 AND IMMUNE COMPLEXES DOWN-REGULATE MONOCYTE ACTIVATION IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 74: 201-201.
- Bakker, P.; Ez-Zaitouni, Z.; Lunteren, M. van; Berg, R. van den; Hooge, M. de; Berg, I.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Reijnierse, M.; Gaalen, F. van & Heijde, D. van der (2015), YOUNG PATIENTS WITH BACK PAIN AND MAXIMALLY 1 SPONDYLOARTHRITIS FEATURE: IS IT NECESSARY TO TEST HLA-B27 OR IMAGE THE SACROILIAC JOINTS?, Annals of the Rheumatic Diseases 74: 628-628.
- Lunteren, M. van; Bakker, P.; Berg, R. van den; Ez-Zaitouni, Z.; Hooge, M. de; Vijver, J. van der; Landewe, R.; Oosterhout, M. van; Lorenzin, M.; Huizinga, T.; Gaalen, F. van & Heijde, D. van der (2015), PERSISTENT WORK PRODUCTIVITY LOSS OVER ONE YEAR IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS AND OTHER FORMS OF CHRONIC BACK PAIN FROM THE SPACE-COHORT, Annals of the Rheumatic Diseases 74: 506-506.
- Bakker, P.; Berg, R. van den; Ez-Zaitouni, Z.; Lunteren, M. van; Hooge, M. de; Fagerli, K.; Turina, M.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Reijnierse, M.; Gaalen, F. van & Heijde, D. van der (2015), REPLACING RADIOGRAPHIC SACROILIITIS BY STRUCTURAL LESIONS ON MRI OF THE SACROILIAC JOINTS: IMPACT ON THE CLASSIFICATION OF PATIENTS ACCORDING TO THE ASAS AXIAL SPA CRITERIA, Annals of the Rheumatic Diseases 74: 874-875.
- Ez-Zaitouni, Z.; Bakker, P.; Hooge, M. de; Berg, R. van den; Lunteren, M. van; Fagerli, K.; Landew,, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Reijnierse, M.; Gaalen, F. van & Heijde, D. van der (2015), LOCAL RADIOLOGISTS SCORE MORE ABNORMALITIES IN COMPARISON TO CENTRAL READERS LEADING TO MORE PATIENTS FULFILLING THE CLASSIFICATION CRITERIA OF AXIAL SPA: DATA FROM THE SPACE-COHORT, Annals of the Rheumatic Diseases 74: 1267-1267.
- Lunteren, M. van; Roeterink, A.; Bakker, P.; Berg, R. van den; Ez-Zaitouni, Z.; Hooge, M. de; Turina, M.; Oosterhout, M. van; Lorenzin, M.; Huizinga, T.; Gaalen, F. van & Heijde, D. van der (2015), HEALTH-RELATED QUALITY OF LIFE IS SUBSTANTIALLY AFFECTED AT BASELINE AND AFTER ONE YEAR IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS AND OTHER FORMS OF CHRONIC BACK PAIN PARTICIPATING IN THE SPACE-COHORT, Annals of the Rheumatic Diseases 74: 1160-1160.
- Bakker, P.; Lunteren, M. van; Ez-Zaitouni, Z.; Berg, R. van den; Hooge, M. de; Berg, I.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Reijnierse, M.; Gaalen, F. van & Heijde, D. van der (2015), SHOULD IMAGING OF THE SI JOINTS BE REPEATED AFTER 1 YEAR? IMPACT ON THE CLASSIFICATION OF PATIENTS ACCORDING TO THE ASAS AXIAL SPA CRITERIA, Annals of the Rheumatic Diseases 74: 753-754.
- Dougados, M.; Huizinga, T.W.J.; Choy, E.H.; Bingham, C.O.; Aassi, M. & Bernasconi, C. (2015), Evaluation of the Disease Activity Score in Twenty-Eight Joints-Based Flare Definitions in Rheumatoid Arthritis: Data From a Three-Year Clinical Trial, ARTHRITIS CARE & RESEARCH 67(12): 1762-1766.
- Messemaker, T.C.; Huizinga, T.W. & Kurreeman, F. (2015), Immunogenetics of rheumatoid arthritis: Understanding functional implications, Journal of Autoimmunity 64: 74-81.
- Emery, P.; Burmester, G.R.; Bykerk, V.P.; Combe, B.G.; Furst, D.E.; Karyekar, C.S.; Wong, D.A. & Huizinga, T.W.J. (2015), PREDICTORS OF DRUG-FREE REMISSION FOLLOWING TREATMENT WITH ABATACEPT (IN COMBINATION WITH METHOTREXATE OR AS MONOTHERAPY) IN EARLY RHEUMATOID ARTHRITIS, Rheumatology 54: 28-29.
- Suurmond, J.; Dorjee, A.L.; Boon, M.R.; Knol, E.F.; Huizinga, T.W.J.; Toes, R.E.M. & Schuerwegh, A.J.M. (2015), Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium (Retraction of vol 12, R150, 2011).
- Peterfy, C.; Burmester, G.R.; Bykerk, V.P.; Combe, B.G.; DiCarlo, J.C.; Furst, D.E.; Huizinga, T.W.J.; Karyekar, C.S.; Wong, D.A.; Conaghan, P. & Emery, P. (2015), SUSTAINED IMPROVEMENTS IN MAGNETIC RESONANCE IMAGING OUTCOMES WITH ABATACEPT FOLLOWING THE WITHDRAWAL OF ALL TREATMENT IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS, Rheumatology 54: 73-74.
- Weinblatt, M.E.; Fleischmann, R.; Vollenhoven, R.F. van; Emery, P.; Huizinga, T.W.J.; Cutolo, M.; Heijde, D. van der; Duncan, B.; Davies, O.; Luijtens, K. & Dougados, M. (2015), Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population.
- Reinards, T.H.C.M.; Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Hoppenreijs, E.P.A.H.; Saurenmann, R.K.; Hinks, A.; Ellis, J.A.; Bakker, E.; Verduijn, W.; Slagboom, P.; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Cate, R. ten & Schilham, M.W. (2015), CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 74(12): 2193-2198.
- Shi, J.; Steenbergen, H.W. van; Nies, J.A.B. van; Levarht, E.W.N.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Toes, R.E.M. & Trouw, L.A. (2015), The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.
- Ajeganova, S. & Huizinga, T.W.J. (2015), Seronegative and seropositive RA: alike but different?, Nature Reviews Rheumatology 11(1): 9-10.
- Nieuwenhuis, W.P.; Newsum, E.C.; Steenbergen, H.W. van; Mangnus, L.; Huizinga, T.W.J.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2015), Is MRI of Use in Identifying Which Undifferentiated Arthritis Patients Will Develop RA?, Arthritis and Rheumatology 67.
- Akdemir, G.; Bijl, A.E. van der; Lange-Brokaar, B.J.E. de; Huizinga, T.W.J.; Allaart, C.F. & Kloppenburg, M. (2015), Inflammation Signs on Magnetic Resonance Imaging in Chronic or Recurrent Gonarthritis Treated with Intra-Articular Infliximab or Corticosteroids, Arthritis and Rheumatology 67.
- Rombouts, Y.; Ewing, E.; Stadt, L.A. van de; Selman, M.H.J.; Trouw, L.A.; Deelder, A.M.; Huizinga, T.W.J.; Wuhrer, M.; Schaardenburg, D. van; Toes, R.E.M. & Scherer, H.U. (2015), Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis, Annals of the Rheumatic Diseases 74(1): 234-241.
- Huizinga, T.W.J.; Conaghan, P.G.; Martin-Mola, E.; Schett, G.; Amital, H.; Xavier, R.M.; Troum, O.; Aassi, M.; Bernasconi, C. & Dougados, M. (2015), Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study, Annals of the Rheumatic Diseases 74(1): 35-43.
- Emery, P.; Burmester, G.R.; Bykerk, V.P.; Combe, B.G.; Furst, D.E.; Barre, E.; Karyekar, C.S.; Wong, D.A. & Huizinga, T.W.J. (2015), Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period, Annals of the Rheumatic Diseases 74(1): 19-26.
- Heimans, L.; Wevers-de Boer, K.V.C.; Ronday, H.K.; Collee, G.; Sonnaville, P.B.J. de; Grillet, B.A.M.; Huizinga, T.W.J. & Allaart, C.F. (2015), Can we prevent rapid radiological progression in patients with early rheumatoid arthritis?, Clinical Rheumatology 34(1): 163-166.
- Wevers-de Boer, K.V.C.; Heimans, L.; Visser, K.; Kalvesten, J.; Goekoop, R.J.; Oosterhout, M. van; Harbers, J.B.; Bijkerk, C.; Steup-Beekman, M.; Buck, M.P.D.M. de; Sonnaville, P.B.J. de; Huizinga, T.W.J. & Allaart, C.F. (2015), Four-month metacarpal bone mineral density loss predicts radiological joint damage progression after 1 year in patients with early rheumatoid arthritis: exploratory analyses from the IMPROVED study, Annals of the Rheumatic Diseases 74(2): 341-346.
- Ercan, E.; Ingo, C.; Tritanon, O.; Magro-Checa, C.; Smith, A.; Smith, S.; Huizinga, T.; Buchem, M.A. van & Ronen, I. (2015), A multimodal MRI approach to identify and characterize microstructural brain changes in neuropsychiatric systemic lupus erythematosus, NeuroImage: Clinical 8: 337-344.
- Heemst, J. van; Hensvold, A.H.; Jiang, X.; Steenbergen, H. van; Klareskog, L.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Catrina, A.I.; Toes, R.E.M.; Lundberg, K. & Woude, D. van der (2015), The Protective Effect of HLA-DRB1*13 Alleles during Specific Phases in the Development of ACPA-Positive RA, Arthritis and Rheumatology 67.
- Nieuwenhuis, W.P.; Steenbergen, H.W. van; Stomp, W.; Stijnen, T.; Huizinga, T.W.J.; Bloem, J.L.; Heijde, D. van der; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2015), The Course of Bone Marrow Edema in Early Undifferentiated and Rheumatoid Arthritis; A Longitudinal MRI Study on Bone Level, Arthritis and Rheumatology 67.
- Steenbergen, H.W. van; Mangnus, L.; Reijnierse, M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2015), Clinical Factors, Anti-Citrullinated Peptide Antibodies and MRI-Detected Subclinical Inflammation in Relation to Progression from Clinically Suspect Arthralgia to Arthritis, Arthritis and Rheumatology 67.
- Brouwers, H.; Jonasdottir, H.; Kwekkeboom, J.; Huizinga, T.; Kloppenburg, M.; Toes, R.; Giera, M. & Ioan-Facsinay, A. (2015), SPECIALIZED PRO-RESOLVING LIPID MEDIATORS IN OSTEOARTHRITIS PATIENTS: EVIDENCE FOR AN ANTI-INFLAMMATORY ROLE, Osteoarthritis and Cartilage 23: A261-A262.
- Gvozdenovic, E.; Wolterbeek, R.; Allaart, C.F.; Brenol, C.; Dougados, M.; Emery, P.; Ferraccioli, G.; Heijde, D. van der; Huizinga, T.W.J.; Kay, J.; Mola, E.M.; Moots, R.J.; Silva, J.A.P. da; Smolen, J.; Veale, D. & Landewe, R.B.M. (2015), Assessment of Global Disease Activity in Rheumatoid Arthritis by Patients and Physicians: Differences Across Countries in the METEOR Database, JCR: Journal of Clinical Rheumatology 21(7): 349-354.
- Krabben, A.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2015), Biomarkers for Radiographic Progression in Rheumatoid Arthritis, Current Pharmaceutical Design 21(2): 147-169.
- Navarro-Compan, V.; Smolen, J.S.; Huizinga, T.W.J.; Landewe, R.; Ferraccioli, G.; Silva, J.A.P. da; Moots, R.J.; Kay, J. & Heijde, D. van der (2015), Quality indicators in rheumatoid arthritis: results from the METEOR database, Rheumatology 54(9): 1630-1639.
- Lenz, T.L.; Deutsch, A.J.; Han, B.; Hu, X.L.; Okada, Y.; Eyre, S.; Knapp, M.; Zhernakova, A.; Huizinga, T.W.J.; Abecasis, G.; Becker, J.; Boeckxstaens, G.E.; Chen, W.M.; Franke, A.; Gladman, D.D.; Gockel, I.; Gutierrez-Achury, J.; Martin, J.; Nair, R.P.; Nothen, M.M.; Onengut-Gumuscu, S.; Rahman, P.; Rantapaa-Dahlqvist, S.; Stuart, P.E.; Tsoi, L.C.; Heel, D.A. van; Worthington, J.; Wouters, M.M.; Klareskog, L.; Elder, J.T.; Gregersen, P.K.; Schumacher, J.; Rich, S.S.; Wijmenga, C.; Sunyaev, S.R.; Bakker, P.I.W. & Raychaudhuri, S. (2015), Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases, Nature Genetics 47(9): 1085-+.
- Mangnus, L.; Steenbergen, H.W. van; Lindqvist, E.; Brouwer, E.; Reijnierse, M.; Huizinga, T.W.J.; Gregersen, P.K.; Berglin, E.; Rantapaa-Dahlqvist, S.; Heijde, D. van der & Helm-van Mil, A.H.M. van der (2015), Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis.
- Heemst, J. van; Trouw, L.A.; Nogueira, L.; Steenbergen, H.W. van; Helm-van Mil, A.H.M. van der; Allaart, C.F.; Serre, G.; Holmdahl, R.; Huizinga, T.W.J.; Toes, R.E.M. & Woude, D. van der (2015), An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.
- Verheul, M.K.; Shiozawa, K.; Levarht, E.W.N.; Huizinga, T.W.J.; Toes, R.E.M.; Trouw, L.A. & Shiozawa, S. (2015), Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent, Rheumatology 54(10): 1930-1932.
- Berg, R. van den; Hooge, M. de; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2015), Percentage of patients with spondyloarthritis in patients referred because of chronic back pain and performance of classification criteria: experience from the Spondyloarthritis Caught Early (SPACE) cohort (vol 52, pg 1492, 2013), Rheumatology 54(7): 1336-1336.
- Steenbergen, H.W. van; Tsonaka, R.; Huizinga, T.W.J.; Cessie, S. le & Helm-van Mil, A.H.M. van der (2015), Predicting the severity of joint damage in rheumatoid arthritis; the contribution of genetic factors, Annals of the Rheumatic Diseases 74(5): 876-882.
- Rooy, D.P.C. de; Tsonaka, R.; Andersson, M.L.E.; Forslind, K.; Zhernakova, A.; Frank-Bertoncelj, M.; Kovel, C.G.F. de; Koeleman, B.P.C.; Heijde, D.M.F.M. van der; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Ospelt, C.; Svensson, B. & Helm-van Mil, A.H.M. van der (2015), Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study, Journal of Rheumatology 42(8): 1383-1391.
- Heemst, J. van; Huizinga, T.J.W.; Woude, D. van der & Toes, R.E.M. (2015), Fine-mapping the human leukocyte antigen locus in rheumatoid arthritis and other rheumatic diseases: identifying causal amino acid variants?, Current Opinion in Rheumatology 27(3): 256-261.
- Fajardo Cristina Lucia Davila, van der Straaten Tahar, Baak Rene, Caballero Catalina Medarde, Barrera Jose Cabeza, Fuentes Salvador Ruiz, Huizinga Tom, Guchelaar Henk-Jan & Swen Jesse (2015), FcGR genetic polymorphisms are related with the response to adalimumab in rheumatoid arthritis patients, International Journal of Clinical Pharmacy 37(1): 183-183.
- Davila-Fajardo, C.L.; Straaten, T. van der; Baak-Pablo, R.; Caballero, C.M.; Barrera, J.C.; Huizinga, T.W.; Guchelaar, H.J. & Swen, J.J. (2015), FcGR genetic polymorphisms and the response to adalimumab in patients with rheumatoid arthritis, Pharmacogenomics 16(4): 373-381.
- Nieuwenhuis, W.P.; Krabben, A.; Stomp, W.; Huizinga, T.W.J.; Heijde, D. van der; Bloem, J.L.; Helm-van Mil, A.H.M. van der & Reijnierse, M. (2015), Evaluation of Magnetic Resonance Imaging-Detected Tenosynovitis in the Hand and Wrist in Early Arthritis, Arthritis and Rheumatology 67(4): 869-876.
- Markusse, I.M.; Dirven, L.; Gerards, A.H.; Groenendael, J.H.L.M. van; Ronday, H.K.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2015), Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study.
- Suurmond, J.; Dorjee, A.L.; Knol, E.F.; Huizinga, T.W.J. & Toes, R.E.M. (2015), Differential TLR-induced cytokine production by human mast cells is amplified by Fc epsilon RI triggering, Clinical and Experimental Allergy 45(4): 788-796.
- Wevers-De Boer, K.V.C.; Heimans, L.; Visser, K.; Schouffoer, A.A.; Molenaar, E.T.H.; Groenendael, J.H.L.M. van; Peeters, A.J.; Speyer, I.; Collee, G.; Huizinga, T.W.J. & Allaart, C.F. (2015), Determinants of reaching drug-free remission in patients with early rheumatoid or undifferentiated arthritis after one year of remission-steered treatment, Rheumatology 54(8): 1380-1384.
- Heemst, J. van; Jansen, D.T.S.L.; Polydorides, S.; Moustakas, A.K.; Bax, M.; Feitsma, A.L.; Bontrop-Elferink, D.G.; Baarse, M.; Woude, D. van der; Wolbink, G.J.; Rispens, T.; Koning, F.; Vries, R.R.P. de; Papadopoulos, G.K.; Archontis, G.; Huizinga, T.W. & Toes, R.E. (2015), Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis, Nature Communications 6.
- Markusse, I.M.; Dirven, L.; Han, K.H.; Ronday, H.K.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2015), Continued Participation in a Ten-Year Tight Control Treat-to-Target Study in Rheumatoid Arthritis: Why Keep Patients Doing their Best?, ARTHRITIS CARE & RESEARCH 67(6): 739-745.
- Krabben, A.; Stomp, W.; Huizinga, T.W.J.; Heijde, D. van der; Bloem, J.L.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2015), Concordance between inflammation at physical examination and on MRI in patients with early arthritis, Annals of the Rheumatic Diseases 74(3): 506-512.
- Steenbergen, H.W. van; Nies, J.A.B. van; Huizinga, T.W.J.; Bloem, J.L.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2015), Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI, Annals of the Rheumatic Diseases 74(6): 1225-1232.
- Steenbergen, H.W. van; Raychaudhuri, S.; Rodriguez-Rodriguez, L.; Rantapaa-Dahlqvist, S.; Berglin, E.; Toes, R.E.M.; Huizinga, T.W.J.; Fernandez-Gutierrez, B.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2015), Association of Valine and Leucine at HLA-DRB1 Position 11 With Radiographic Progression in Rheumatoid Arthritis, Independent of the Shared Epitope Alleles but Not Independent of Anti-Citrullinated Protein Antibodies, Arthritis and Rheumatology 67(4): 877-886.
- Schaarenburg, R.A. van; Daha, N.A.; Schonkeren, J.J.M.; Levarht, E.W.N.; Gijlswijk-Janssen, D.J. van; Kurreeman, F.A.S.; Roos, A.; Kooten, C. van; Koelman, C.A.; Ernst-Kruis, M.R.; Toes, R.E.M.; Huizinga, T.W.J.; Lankester, A.C. & Trouw, L.A. (2015), Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections, Immunobiology 220(3): 422-427.
- Jansen, D.T.S.L.; Hameetman, M.; Bergen, J. van; Huizinga, T.W.J.; Heijde, D. van der; Toes, R.E.M. & Gaalen, F.A. van (2015), IL-17-producing CD4(+) T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities, Rheumatology 54(4): 728-735.
- Steenbergen, H.W. van; Nies, J.A.B. van; Ruyssen-Witrand, A.; Huizinga, T.W.J.; Cantagrel, A.; Berenbaum, F. & Helm-van Mil, A.H.M. van der (2015), IL2RA is associated with persistence of rheumatoid arthritis.
- Schaarenburg, R.A. van; Schejbel, L.; Truedsson, L.; Topaloglu, R.; Al-Mayouf, S.M.; Riordan, A.; Simon, A.; Kallel-Sellami, M.; Arkwright, P.D.; Ahlin, A.; Hagelberg, S.; Nielsen, S.; Shayesteh, A.; Morales, A.; Tam, S.; Genel, F.; Berg, S.; Ketel, A.G.; Berg, J.M. van den; Kuijpers, T.W.; Olsson, R.F.; Huizinga, T.W.J.; Lankester, A.C. & Trouw, L.A. (2015), Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency, Journal of Autoimmunity 62: 39-44.
- Behrens, F.; Tak, P.P.; Ostergaard, M.; Stoilov, R.; Wiland, P.; Huizinga, T.W.; Berenfus, V.Y.; Vladeva, S.; Rech, J.; Rubbert-Roth, A.; Korkosz, M.; Rekalov, D.; Zupanets, I.A.; Ejbjerg, B.J.; Geiseler, J.; Fresenius, J.; Korolkiewicz, R.P.; Schottelius, A.J. & Burkhardt, H. (2015), MOR103, a human monoclonal antibody to granulocyte-macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial, Annals of the Rheumatic Diseases 74(6): 1058-1064.
- Huizinga, T.W.J. (2015), Personalized medicine in rheumatoid arthritis: is the glass half full or half empty?, Journal of Internal Medicine 277(2): 178-187.
- Nies, J.A.B. van; Alves, C.; Radix-Bloemen, A.L.S.; Gaujoux-Viala, C.; Huizinga, T.W.J.; Hazes, J.M.W.; Brouwer, E.; Fautrel, B. & Helm-van Mil, A.H.M. van der (2015), Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis: results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH.
- Markusse, I.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2015), Response to 'Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis' - authors' reply.
- Genovese, M.C.; Fleischmann, R.; Kivitz, A.J.; Rell-Bakalarska, M.; Martincova, R.; Fiore, S.; Rohane, P.; Hoogstraten, H. van; Garg, A.; Fan, C.P.; Adelsberg, J. van; Weinstein, S.P.; Graham, N.M.H.; Stahl, N.; Yancopoulos, G.D.; Huizinga, T.W.J. & Heijde, D. van der (2015), Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate Results of a Phase III Study, Arthritis and Rheumatology 67(6): 1424-1437.
- Bosch, W.B. van den; Mangnus, L.; Reijnierse, M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2015), The diagnostic accuracy of the squeeze test to identify arthritis: a cross-sectional cohort study, Annals of the Rheumatic Diseases 74(10): 1886-1889.
- Schaarenburg, R. van; Suurmond, J.; Huizinga, T.; Toes, R. & Trouw, L. (2015), The production and secretion of complement factor C1q by human mast cells, Molecular Immunology 67(1): 191-191.
- Suurmond, J.; Rivellese, F.; Dorjee, A.L.; Bakker, A.M.; Rombouts, Y.J.P.C.; Rispens, T.; Wolbink, G.; Zaldumbide, A.; Hoeben, R.C.; Huizinga, T.W.J. & Toes, R.E.M. (2015), Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies, Annals of the Rheumatic Diseases 74(10): 1915-1923.
- Toes, R.E.M. & Huizinga, T.J.W. (2015), Update on autoantibodies to modified proteins, Current Opinion in Rheumatology 27(3): 262-267.
- Gan, R.W.; Trouw, L.A.; Shi, J.; Toes, R.E.M.; Huizinga, T.W.J.; Demoruelle, M.K.; Kolfenbach, J.R.; Zerbe, G.O.; Deane, K.D.; Edison, J.D.; Gilliland, W.R.; Norris, J.M. & Holers, V.M. (2015), Anti-carbamylated Protein Antibodies Are Present Prior to Rheumatoid Arthritis and Are Associated with Its Future Diagnosis, Journal of Rheumatology 42(4): 572-579.
- Stoop, J.N.; Fischer, A.; Hayer, S.; Hegen, M.; Huizinga, T.W.J.; Steiner, G.; Trouw, L.A. & Toes, R.E.M. (2015), Anticarbamylated protein antibodies can be detected in animal models of arthritis that require active involvement of the adaptive immune system, Annals of the Rheumatic Diseases 74(5): 949-950.
- Habets, K.L.L.; Trouw, L.A.; Levarht, E.W.N.; Korporaal, S.J.A.; Habets, P.A.M.; Groot, P. de; Huizinga, T.W.J. & Toes, R.E.M. (2015), Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.
- Lange-Brokaar, B.J.E. de; Ioan-Facsinay, A.; Yusuf, E.; Visser, A.W.; Kroon, H.M.; Osch, G.J.V.M. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Bloem, J.L.; Nelissen, R.G.H.H.; Huizinga, T.W. & Kloppenburg, M. (2015), Association of Pain in Knee Osteoarthritis With Distinct Patterns of Synovitis, Arthritis and Rheumatology 67(3): 733-740.
- Kooij, S.M. van der; Buchem, M.A. van; Overbeek, O.M.; Dijkman, G. & Huizinga, T.W.J. (2015), Susac syndrome: a report of four cases and a review of the literature, Netherlands Journal of Medicine 73(1): 10-16.
- Steenbergen, H.W. van; Rodriguez-Rodriguez, L.; Berglin, E.; Zhernakova, A.; Knevel, R.; Ivorra-Cortes, J.; Huizinga, T.W.J.; Fernandez-Gutierrez, B.; Gregersen, P.K.; Rantapaa-Dahlqvist, S. & Helm-van Mil, A.H.M. van der (2015), A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis.
- Rivellese, F.; Suurmond, J.; Habets, K.; Dorjee, A.L.; Ramamoorthi, N.; Townsend, M.J.; Paulis, A. de; Marone, G.; Huizinga, T.W.J.; Pitzalis, C. & Toes, R.E.M. (2015), Ability of Interleukin-33-and Immune Complex-Triggered Activation of Human Mast Cells to Down-Regulate Monocyte-Mediated Immune Responses, Arthritis and Rheumatology 67(9): 2343-2353.
- Jansen, D.T.S.L.; Bannoudi, H. el; Arens, R.; Habets, K.L.L.; Hameetman, M.; Huizinga, T.W.J.; Stoop, J.N. & Toes, R.E.M. (2015), Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.
- Huizinga, T. & Knevel, R. (2015), 2014 treat-to-target RA recommendations-strategy is key, Nature Reviews Rheumatology 11(9): 509-511.
- Stomp, W.; Krabben, A.; Heijde, D. van der; Huizinga, T.W.J.; Bloem, J.L.; Ostergaard, M.; Helm-van Mil, A.H.M. van der & Reijnierse, M. (2015), Aiming for a simpler early arthritis MRI protocol: can Gd contrast administration be eliminated?, European Radiology 25(5): 1520-1527.
- Bossini-Castillo, L.; Kovel, C. de; Kallberg, H.; Slot, R. van 't; Italiaander, A.; Coenen, M.; Tak, P.P.; Posthumus, M.D.; Wijmenga, C.; Huizinga, T.; Helm-van Mil, A.H.M. van der; Stoeken-Rijsbergen, G.; Rodriguez-Rodriguez, L.; Balsa, A.; Gonzalez-Alvaro, I.; Gonzalez-Gay, M.A.; Gomez-Vaquero, C.; Franke, B.; Vermeulen, S.; Horst-Bruinsma, I.E. van der; Dijkmans, B.A.C.; Wolbink, G.J.; Ophoff, R.A.; Maehlen, M.T.; Riel, P. van; Merriman, M.; Klareskog, L.; Lie, B.A.; Merriman, T.; Crusius, J.B.A.; Brouwer, E.; Martin, J.; Vries, N. de; Toes, R.; Padyukov, L.; Koeleman, B.P.C. & LifeLines Cohort Study (2015), A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides, Annals of the Rheumatic Diseases 74(3).
- Derksen, V.F.A.M.; Ajeganova, S.; va der Helm-van Mil, A.H.M.; Hafstrom, I.; Huizinga, T.W.J.; Toes, R.E.M.; Trouw, L.A.; Svensson, B. & Woude, D. van der (2015), Rheumatoid Arthritis Patients with Many Autoantibodies Have Different Characteristics at Presentation Compared to Patients with Few Autoantibodies, Arthritis and Rheumatology 67.
- Messemaker, T.C.; Huizinga, T.W. & Kurreeman, F. (2015), Immunogenetics of rheumatoid arthritis: Understanding functional implications, Journal of Autoimmunity.
- Markusse, I.; Dirven, L.; vd Broek, M.; Akdemir, G.; Goekoop-Ruiterman, Y.; Han, H.; Kerstens, P.; Lems, W.; Huizinga, T. & Allaart, C. (2014), 10 YEARS OF TREAT-TO-TARGET THERAPY IN RHEUMATOID ARTHRITIS PATIENTS (THE BEST STUDY): CLINICAL AND RADIOGRAPHIC OUTCOMES, Annals of the Rheumatic Diseases 73: 272-273.
- Schiff, M.; Combe, B.; Dorner, T.; Kremer, J.M.; Huizinga, T.W.; Veenhuizen, M.; Gill, A.; Zou, H.; Komocsar, W.; Berclaz, P.Y.; Ortmann, R. & Lee, C. (2014), EFFICACY AND SAFETY OF TABALUMAB, AN ANTI-B CELL ACTIVATING FACTOR MONOCLONAL ANTIBODY, IN PATIENTS WITH RHEUMATOID ARTHRITIS WHO HAD AN INADEQUATE RESPONSE TO TNF-ALPHA INHIBITORS: RESULTS FROM A PHASE 3 MULTICENTER, RANDOMIZED, DOUBLE-BLIND STUDY, Annals of the Rheumatic Diseases 73: 952-953.
- Steenbergen, H.W. van; Nies, J.A. van; Huizinga, T.W.; Reijnierse, M. & Helm-van Mil, A.H. van der (2014), SUBCLINICAL INFLAMMATION ON MRI OF HAND AND FOOT OF ACPA-NEGATIVE ARTHRALGIA PATIENTS AT RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 73: 469-469.
- Nieuwenhuis, W.P.; Krabben, A.; Stomp, W.; Bloem, J.L.; Huizinga, T.W.J.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2014), EVALUATING MRI-DETECTED TENOSYNOVITIS IN EARLY ARTHRITIS, Annals of the Rheumatic Diseases 73: 670-670.
- Abawi, O.; vd Berg, R.; vd Heijde, D.; Hooge, M. de; Bakker, P.; Reijnierse, M.; Huizinga, T. & Gaalen, F. van (2014), EVALUATION OF THE TWO-STEP REFERRAL STRATEGY FOR AXIAL SPONDYLOARTHRITIS IN THE SPONDYLOARTHRITIS CAUGHT EARLY COHORT, Annals of the Rheumatic Diseases 73: 425-426.
- Nies, J.A. van; Alves, C.; Gaujoux-Viala, C.; Radix-Bloemen, A.L.; Huizinga, T.W.; Hazes, J.M.; Brouwer, E.; Fautrel, B. & Helm-van Mil, A.H. van der (2014), REAPPRAISAL OF THE DIAGNOSTIC AND PROGNOSTIC VALUE OF MORNING STIFFNESS IN ARTHRALGIA, EARLY ARTHRITIS AND EARLY RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 73: 339-339.
- Nies, J.A. van; Steenbergen, H.W. van; Krabben, A.; Stomp, W.; Huizinga, T.W.; Reijnierse, M. & Helm-van Mil, A.H. van der (2014), EXPLORING SYMPTOM DURATION, AUTO ANTIBODIES AND INFLAMMATION IN ORDER TO EXPLAIN THE PREDICTIVE VALUE OF BASELINE EROSIONS FOR FUTURE STRUCTURAL DAMAGE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 73: 513-513.
- Steenbergen, H.W. van; Rodriguez-Rodriguez, L.; Rantapaa-Dahlqvist, S.; Berglin, E.; Huizinga, T.W.; Fernandez-Gutierrez, B.; Gregersen, P.K. & Helm-van Mil, A.H. van der (2014), GENETIC VARIANTS IN IL-6, IL-10, C5-TRAF1 AND FCRL3 AND PROGRESSION OF JOINT DAMAGE IN RHEUMATOID ARTHRITIS; A STUDY ON SIX COHORTS, Annals of the Rheumatic Diseases 73: 345-345.
- Markusse, I.; Dirven, L.; Han, H.; Ronday, K.; Kerstens, P.; Lems, W.; Huizinga, T. & Allaart, C. (2014), GOOD ADHERENCE OF RHEUMATOLOGISTS TO A 10 YEAR TREAT-TO-TARGET PROTOCOL FOR PATIENTS WITH RECENT-ONSET RHEUMATOID ARTHRITIS (THE BEST STUDY), Annals of the Rheumatic Diseases 73: 401-401.
- Bakker, P.; Hooge, M. de; Berg, R. van den; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2014), IMPACT OF REPEATING IMAGING OF THE SACRO-ILIAC JOINTS OVER ONE YEAR ON THE CLASSIFICATION ACCORDING THE ASAS AXIAL SPA CRITERIA OF PATIENTS, Annals of the Rheumatic Diseases 73: 426-427.
- Emery, P.; Burmester, G.; Bykerk, V.; Combe, B.; Furst, D.E.; Barre, E.; Karyekar, C.S.; Wong, D. & Huizinga, T.W. (2014), INDUCTION OF CLINICAL REMISSION FOLLOWED BY DRUG-FREE WITHDRAWAL WITH ABATACEPT COMBINATION AND MONOTHERAPY IN EARLY RA: RESULTS FROM THE AVERT STUDY OVER 18 MONTHS, Annals of the Rheumatic Diseases 73: 69-69.
- Genovese, M.; Fleischmann, R.M.; Kivitz, A.J.; Rell-Bakalarska, M.; Martincova, R.; Fiore, S.; Rohane, P.; Hoogstraten, H. van; Fan, C.; Adelsberg, J. van; Weinstein, S.; Graham, N.; Stahl, N.; Yancopoulos, G.; Huizinga, T.W. & Heijde, D. van der (2014), EFFECTS OF SARILUMAB PLUS MTX ON CLINICAL, RADIOGRAPHIC, AND FUNCTIONAL ENDPOINTS IN PATIENTS WITH MODERATE-TO-SEVERE RHEUMATOID ARTHRITIS: RESULTS OF A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, INTERNATIONAL STUDY, Annals of the Rheumatic Diseases 73: 70-70.
- Bakker, P.; Berg, R. van den; Hooge, M. de; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2014), DO BONE MARROW EDEMA LESIONS IN THE SACROILIAC JOINT CHANGE INTO FATTY LESIONS OVER A 1-YEAR PERIOD IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS OR POSSIBLE SPONDYLOARTHRITIS, Annals of the Rheumatic Diseases 73: 663-664.
- Steenbergen, H.W. van; Luijk, R.; Heijmans, B.T.; Huizinga, T.W.; Shoemaker, R. & Helm-van Mil, A.H. van der (2014), DNA METHYLATION IN RELATION TO ARTHRITIS PERSISTENCY: AN EPIGENOME WIDE-STUDY, Annals of the Rheumatic Diseases 73: 135-136.
- Roeterink, A.; Hooge, M. de; vd Vijver, J.; vd Berg, R.; Dagfinrud, H.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; vd Heijde, D. & Gaalen, F. van (2014), DISEASE ACTIVITY IS STRONGLY ASSOCIATED WITH WORK PRODUCTIVITY AND PHYSICAL HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS IN THE SPACE-COHORT, Annals of the Rheumatic Diseases 73: 421-421.
- Pellegrom, S.; Hooge, M. de; Huizinga, T.; Heijde, D. van der & Gaalen, F. van (2014), PERFORMANCE OF REFERRAL PARAMETERS OF PATIENTS WITH CHRONIC BACK PAIN INCLUDED IN THE SPONDYLOARTHRITIS CAUGHT EARLY COHORT (SPACE), Annals of the Rheumatic Diseases 73: 1041-1041.
- Peterfy, C.; Burmester, G.; Bykerk, V.; Combe, B.; Furst, D.E.; Huizinga, T.W.; Karyekar, C.S.; Wong, D.; Conaghan, P. & Emery, P. (2014), MRI RESULTS FROM THE AVERT STUDY: A RANDOMIZED, ACTIVE-CONTROLLED TRIAL TO EVALUATE INDUCTION OF REMISSION AND MAINTENANCE OF DRUG-FREE REMISSION USING ABATACEPT IN COMBINATION WITH METHOTREXATE OR AS MONOTHERAPY IN PATIENTS WITH EARLY RA, Annals of the Rheumatic Diseases 73: 71-71.
- Huizinga, T. (2014), NEURO-PSYCHIATRIC COMPLICATIONS OF SLE, Rheumatology 53: 10-10.
- Steenbergen, H.W. van; Tsonaka, R.; Huizinga, T.W. & Helm-van Mil, A.H. van der (2014), THE COURSE OF FATIGUE IN RHEUMATOID ARTHRITIS; A 10 YEAR LONGITUDINAL COHORT STUDY, Annals of the Rheumatic Diseases 73: 447-448.
- Buckley, F.; Finckh, A.; Huizinga, T.W.J.; Dejonckheere, F. & Jansen, J.P. (2014), COMPARATIVE EFFICACY OF NOVEL DISEASE-MODIFYING ANTIRHEUMATIC DRUGS AS MONOTHERAPY AND IN COMBINATION WITH METHOTREXATE IN RHEUMATOID ARTHRITIS PATIENTS WITH AN INADEQUATE RESPONSE TO TRADITIONAL DMARDS: A NETWORK META-ANALYSIS, Rheumatology 53: 88-89.
- Checa, C.M.; Zirkzee, E.J.M.; Beaart, H.J.L.; Sohrabian, A.; Ronnelid, J.; Trouw, L.A.; Huizinga, T.W.J. & Steup-Beekman, G.M. (2014), CLUSTER ANALYSIS OF AN ARRAY OF AUTOANTIBODIES IN NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS (NPSLE), Annals of the Rheumatic Diseases 73: 532-533.
- Huizinga, T.W.; Conaghan, P.G.; Martin-Mola, E.; Schett, G.; Amital, H.; Xavier, R.M.; Troum, O.; Aassi, M.; Bernasconi, C. & Dougados, M. (2014), CLINICAL AND RADIOGRAPHIC OUTCOMES AT 2 YEARS AND THE EFFECT OF TOCILIZUMAB DISCONTINUATION FOLLOWING SUSTAINED REMISSION IN THE SECOND AND THIRD YEAR OF THE ACT-RAY STUDY, Annals of the Rheumatic Diseases 73: 685-685.
- Steenbergen, H.W. van; Nies, J.A. van; Huizinga, T.W.; Bloem, J.L.; Reijnierse, M. & Helm-van Mil, A.H. van der (2014), CHARACTERISING ARTHRALGIA IN THE PRECLINICAL PHASE OF RHEUMATOID ARTHRITIS USING MAGNETIC RESONANCE IMAGING, Annals of the Rheumatic Diseases 73: 127-127.
- Roeterink, A.; Hooge, M. de; Vijver, J. van der; Berg, R. van der; Dagfinrud, H.; Turina, M.; Oosterhout, M. van; Ramonda, R.; Huizinga, T.; Heijde, D. van der & Gaalen, F. van (2014), A SUBSTANTIAL DECREASE IN WORK PRODUCTIVITY AND PHYSICAL HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH CHRONIC BACK PAIN IN THE SPACE-COHORT, Annals of the Rheumatic Diseases 73: 198-198.
- Gvozdenovic, E.; Allaart, C.; Wolterbeek, R.; Brenol, C.; Chopra, A.; Dougados, M.; Emery, P.; Ferraccioli, G.; Heijde, D. van der; Huizinga, T.; Kay, J.; Mola, E.; Moots, R.; Silva, J. da; Smolen, J.; Veale, D. & Landewe, R. (2014), ASSESSMENT OF GLOBAL DISEASE ACTIVITY IN RA BY PATIENTS AND PHYSICIANS: CULTURAL DIFFERENCES ACROSS COUNTRIES IN THE METEOR DATABASE, Annals of the Rheumatic Diseases 73: 336-336.
- Shi, J.; Stadt, L. van de; Levarht, N.; Huizinga, T.; Hamann, D.; Schaardenburg, D. van; Toes, R. & Trouw, L. (2014), ANTI-CARBAMYLATED PROTEIN ANTIBODIES (ANTI-CARP) PRECEDE THE ONSET OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 73: 385-386.
- Koppejan, H.; Hitchon, C.; Trouw, L.; Sokolove, J.; Huizinga, T.W.; Toes, R. & El-Gabalawy, H. (2014), ANTI-CARBAMYLATED ANTIBODIES IN CANADIAN FIRST NATION RA PATIENTS, FIRST DEGREE RELATIVES AND CONTROLS IN RELATION TO ACPA AND RF PRESENCE AND ACPA EPITOPE SPREAD, Annals of the Rheumatic Diseases 73: 127-128.
- Akdemir, G.; Markusse, I.; Dirven, L.; Broek, M. van den; Molenaar, E.; Schouffoer, A.; Kerstens, P.; Lems, W.; Huizinga, T. & Allaart, C. (2014), ACPA-NEGATIVE RA PATIENTS BENEFIT FROM INITIAL COMBINATION THERAPY WITH EARLY CLINICAL IMPROVEMENT - A SUB-ANALYSIS OF THE BEST STUDY, Annals of the Rheumatic Diseases 73: 271-272.
- Nies, J.A. van; Gaujoux-Viala, C.; Tsonaka, R.; Huizinga, T.W.; Fautrel, B. & Helm-Van Mil, A.H. van der (2014), WHEN DOES THE THERAPEUTIC WINDOW OF OPPORTUNITY IN RHEUMATOID ARTHRITIS CLOSE? A STUDY IN TWO EARLY RA COHORTS, Annals of the Rheumatic Diseases 73: 73-73.
- Rivellese, F.; Suurmond, J.; Paulis, A. de; Marone, G.; Huizinga, T.W.J. & Toes, R.E.M. (2014), IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation, European Journal of Immunology 44(10): 3045-3055.
- Shi, J.; Stadt, L.A. van de; Verheul, M.; Levarht, E.W.N.; Huizinga, T.W.J.; Hamann, D.; Schaardenburg, D. van; Toes, R.E.M. & Trouw, L.A. (2014), ANTI-CARBAMYLATED PROTEIN ANTIBODIES (ANTI-CARP) PRECEDE THE ONSET OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 73: A21-A21.
- Jiang, X.; Trouw, L.A.; Wesemael, T.J. van; Shi, J.; Kallberg, H.; Malmstrom, V.; Israelsson, L.; Hreggvidsdottir, H.; Verduijn, W.; Klareskog, L.; Alfredsson, L.; Huizinga, T.W.J.; Toes, R.E.M.; Lundberg, K. & Woude, D. van der (2014), ANTI-CARP ANTIBODIES IN TWO LARGE COHORTS OF PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR RELATIONSHIP TO GENETIC RISK FACTORS AND SMOKING, Annals of the Rheumatic Diseases 73: A11-A12.
- Verheul, M.K.; Stoop, J.N.; Liu, B.S.; Shi, J.; Jansen, D.T.S.L.; Hegen, M.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2014), DEVELOPMENT OF ANTIBODIES SPECIFIC FOR CARBAMYLATED PROTEIN PRECEDES DISEASE ONSET IN MICE WITH COLLAGEN-INDUCED ARTHRITIS, Annals of the Rheumatic Diseases 73: A23-A24.
- Zirkzee, E.J.M.; Steup-Beekman, G.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2014), Health care in systemic lupus erythematosus (SLE): the patient's perspective, Clinical Rheumatology 33(9): 1279-1287.
- Muhammad, A.; Wesemael, T. van; Kochi, Y.; Mjaavatten, M.D.; Wevers-de Boer, K.; Allaart, C.F.; Trouw, L.A.; Suzuki, A.; Yamamoto, K.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Woude, D. van der (2014), IN RHEUMATOID ARTHRITIS, SMOKING IS NOT PRIMARILY ASSOCIATED WITH ANTI-CITRULLINAGED PROTEIN ANTIBODIES, BUT WITH THE PRESENCE OF SEVERAL AUTOANTIBODIES, Annals of the Rheumatic Diseases 73: A12-A12.
- Rooy, D.P.C. de; Nies, J.A.B. van; Kapetanovic, M.C.; Kristjansdottir, H.; Andersson, M.L.E.; Forslind, K.; Heijde, D.M.F.M. van der; Gregersen, P.K.; Lindqvist, E.; Huizinga, T.W.J.; Grondal, G.; Svensson, B. & Helm-van Mil, A.H.M. van der (2014), Smoking as a risk factor for the radiological severity of rheumatoid arthritis: a study on six cohorts, Annals of the Rheumatic Diseases 73(7): 1384-1387.
- Liu, B.S.; Cao, Y.H.; Huizinga, T.W.; Hafler, D.A. & Toes, R.E.M. (2014), TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells, European Journal of Immunology 44(7): 2121-2129.
- Diamantopoulos, A.; Finckh, A.; Huizinga, T.; Sungher, D.K.; Sawyer, L.; Neto, D. & Dejonckheere, F. (2014), Tocilizumab in the Treatment of Rheumatoid Arthritis: A Cost-Effectiveness Analysis in the UK, PharmacoEconomics 32(8): 775-787.
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- Burmester, G.; Furst, D.E.; Combe, B.G.; Huizinga, T.W.J.; Bykerk, V.P.; Wong, D.; Karyekar, C.S. & Emery, P. (2014), Stringent Criteria for Low Disease Activity and Remission after 12 Months of Treatment, and after Treatment Withdrawal, with Abatacept Monotherapy, Abatacept with Methotrexate or Methotrexate Alone in Early Rheumatoid Arthritis., Arthritis and Rheumatology 66: S1076-S1076.
- Peterfy, C.; Burmester, G.; DiCarlo, V.P.B.B.G.C.J.C.; Combe, B.G.; DiCarlo, J.C.; Furst, D.E.; Huizinga, T.W.J.; Karyekar, C.S.; Wong, D.; Conaghan, P.G. & Emery, P. (2014), Sustained Improvements in Magnetic Resonance Imaging Outcomes with Abatacept Following the Withdrawal of All Treatment in Patients with Early Rheumatoid Arthritis., Arthritis and Rheumatology 66: S669-S669.
- Markusse, I.M.; Meijs, J.; Boer, B. de; Schouffoer, A.A.; Marsan, N.A.; Kroft, L.J.M.; Ninaber, M.K.; Huizinga, T.W.J. & Vries-Bouwstra, J.K. de (2014), The Additive Value of Nailfold Videocapillaroscopy Patterns to Disease-Specific Autoantibodies in Discrimination of Patients with Systemic Sclerosis at Risk for Severe Organ Involvement., Arthritis and Rheumatology 66: S745-S746.
- Huizinga, T.W.J.; Connolly, S.E.; Furst, D.E.; Bykerk, V.P.; Burmester, G.; Combe, B.G.; Karyekar, C.S.; Wong, D.; Trouw, L.; Toes, R.E.M. & Emery, P. (2014), The Impact on Anti-Citrullinated Protein Antibody Isotypes and Epitope Fine Specificity in Patients with Early RA Treated with Abatacept and Methotrexate., Arthritis and Rheumatology 66: S666-S666.
- Shi, J.; Steenbergen, H.W. van; Nies, J.A.B. van; Levarht, E.W.N.; Helm-van Mil, A.H.M.V. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2014), The Specificity of Anti-Carbamylated Protein Antibodies for Rheumatoid Arthritis in a Setting of Early Arthritis., Arthritis and Rheumatology 66: S194-S194.
- Scherer, H.U.; Rombouts, Y.; Willemze, A.; Beers, J. van; Shi, J.; Kerkman, P.; Janssen, G.; Veelen, P. van; Zaldumbide, A.; Hoeben, R.; Pruijn, G.; Deelder, A.; Wolbink, G.J.; Rispens, T.; Huizinga, T.W.; Wuhrer, M.; Trouw, L. & Toes, R. (2014), A HIGH FREQUENCY OF N-GLYCANS IN THE ACPA-IGG VARIABLE DOMAIN MODULATES REACTIVITY TO CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 73: 129-129.
- Suwannalai, P.; Britsemmer, K.; Knevel, R.; Scherer, H.U.; Levarht, E.W.N.; Helm-van Mil, A.H. van der; Schaardenburg, D. van; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2014), Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis, Annals of the Rheumatic Diseases 73(1): 270-276.
- Huizinga, T.W.J.; Fleischmann, R.M.; Jasson, M.; Radin, A.R.; Adelsberg, J. van; Fiore, S.; Huang, X.H.; Yancopoulos, G.D.; Stahl, N. & Genovese, M.C. (2014), Sarilumab, a fully human monoclonal antibody against IL-6R alpha in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial, Annals of the Rheumatic Diseases 73(9): 1626-1634.
- Knevel, R.; Klein, K.; Somers, K.; Ospelt, C.; Houwing-Duistermaat, J.J.; Nies, J.A.B. van; Rooy, D.P.C. de; Bock, L. de; Kurreeman, F.A.S.; Schonkeren, J.; Stoeken-Rijsbergen, G.; Helmer, Q.; Linden, M.P.M. van der; Kern, M.; Manjarrez-Orduno, N.; Rodriguez-Rodriquez, L.; Stinissen, P.; Huizinga, T.W.J.; Toes, R.E.M.; Gay, S.; Gregersen, P.K.; Somers, V. & Helm-van Mil, A.H.M. van der (2014), Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis., Annals of the Rheumatic Diseases 73(11): 2038-46.
- Nies, J.A.B. van; Krabben, A.; Schoones, J.W.; Huizinga, T.W.J.; Kloppenburg, M. & Helm-van Mil, A.H.M. van der (2014), What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review, Annals of the Rheumatic Diseases 73(5): 861-870.
- Boer, B. de; Meijs, J.; Aken, J. van; Huizinga, T.W.J.; Schouffoer, A.A. & Vries-Bouwstra, J.K. de (2014), The Value of Repeated Nailfold Capillaroscopy in Raynaud's Phenomenon in Daily Practice: A Follow-up Study in the Netherlands., Arthritis and Rheumatology 66: S849-S850.
- Meijs, J.; Zirkzee, E.J.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Stijnen, T.; Huizinga, T.W.J.; Schuerwegh, A.J.M. & Vlieland, T.P.M.V. (2014), Health-care utilization in Dutch systemic sclerosis patients, Clinical Rheumatology 33(6): 825-832.
- Markusse, I.M.; Vries-Bouwstra, J.K. de; Han, K.H.; Lubbe, P.A.H.M. van der; Schouffoer, A.A.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2014), Feasibility of tailored treatment based on risk stratification in patients with early rheumatoid arthritis.
- Nies, J.A.B. van; Steenbergen, H.W. van; Krabben, A.; Stomp, W.; Huizinga, T.W.J.; Reijnierse, M. & Helm-van Mill, A.H.M. van der (2014), Evaluating processes underlying the predictive value of baseline erosions for future radiological damage in early rheumatoid arthritis, Annals of the Rheumatic Diseases 74(5): 883-889.
- Jiang, X.; Trouw, L.A.; Wesemael, T.J. van; Shi, J.; Bengtsson, C.; Kallberg, H.; Malmstrom, V.; Israelsson, L.; Hreggvidsdottir, H.; Verduijn, W.; Klareskog, L.; Alfredsson, L.; Huizinga, T.W.J.; Toes, R.E.M.; Lundberg, K. & Woude, D. van der (2014), Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies., Annals of the Rheumatic Diseases 73(10): 1761-8.
- Stomp, W.; Krabben, A.; Heijde, D. van der; Huizinga, T.W.J.; Bloem, J.L.; Helm-van Mil, A.H.M. van der & Reijnierse, M. (2014), Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema?, European Radiology 24(10): 2614-22.
- Yarwood, A.; Huizinga, T.W.J. & Worthington, J. (2014), The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA., Rheumatology.
- Huizinga, T.W.J.; Fleischmann, R.M.; Jasson, M.; Radin, A.R.; Adelsberg, J. van; Fiore, S.; Huang, X.H.; Yancopoulos, G.D.; Stahl, N. & Genovese, M.C. (2014), Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial., Annals of the Rheumatic Diseases 73(9): 1626-34.
- Krabben, A.; Stomp, W.; Nies, J.A.B. van; Huizinga, T.W.J.; Heijde, D. van der; Bloem, J.L.; Reijnierse, M. & Helm-Van Mil, A.H.M. van der (2014), MRI-detected subclinical joint inflammation is associated with radiographic progression., Annals of the Rheumatic Diseases.
- Karakaya, B.; Moorsel, C.H.M. van; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Ruven, H.J.T.; Vis, J.J. van der & Grutters, J.C. (2014), Macrophage migration inhibitory factor (MIF) -173 polymorphism is associated with clinical erythema nodosum in Löfgren's syndrome.
- Gaalen, F. van; Berg, R. van den; Verhoog, I.; Schonkeren, J.; Helm-van Mil, A. van der; Huizinga, T. & Heijde, D.M. van der (2014), Is HLA-B27 Increased in Patients Diagnosed with Undifferentiated Arthritis? Results from the Leiden Early Arthritis Cohort., Journal of Rheumatology.
- Rivellese, F.; Suurmond, J.; Paulis, A. de; Marone, G.; Huizinga, T.W.J. & Toes, R.E.M. (2014), IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation., European Journal of Immunology.
- Heemst, J. van; Woude, D. van der; Huizinga, T.W. & Toes, R.E. (2014), HLA and rheumatoid arthritis: how do they connect?
- Zirkzee, E.J.M.; Steup-Beekman, G.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2014), Health care in systemic lupus erythematosus (SLE): the patient's perspective.
- Berg, M.H. van den; Dulmen-den Broeder, E. van; Overbeek, A.; Ronckers, C.M.; Dorp, W. van; Kremer, L.C.; Heuvel-Eibrink, M.M. van den; Huizinga, G.A.; Loonen, J.J.; Versluys, A.B.; Bresters, D.; Lambalk, C.B.; Kaspers, G.J.L. & Leeuwen, F.E. van (2014), Fertility studies in female childhood cancer survivors: selecting appropriate comparison groups.
- Markusse, I.M.; Akdemir, G.; Huizinga, T.W.J. & Allaart, C.F. (2014), Drug-free holiday in patients with rheumatoid arthritis: a qualitative study to explore patients' opinion.
- Huizinga, T.W.J.; Conaghan, P.G.; Martin-Mola, E.; Schett, G.; Amital, H.; Xavier, R.M.; Troum, O.; Aassi, M.; Bernasconi, C. & Dougados, M. (2014), Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study., Annals of the Rheumatic Diseases.
- Reinards, T.H.C.M.; Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Rossum, M.A.J. van; Girschick, H.J.; Wouters, C.; Hoppenreijs, E.P.A.H.; Saurenmann, R.K.; Hinks, A.; Ellis, J.A.; Bakker, E.; Verduijn, W.; Slagboom, P.; Huizinga, T.W.J.; Toes, R.E.M.; Houwing-Duistermaat, J.J.; Cate, R. ten & Schilham, M.W. (2014), CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis., Annals of the Rheumatic Diseases.
- Krabben, A.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2014), Biomarkers for radiographic progression in rheumatoid arthritis., Current Pharmaceutical Design.
- Kraaij, T.; Huizinga, T.W.J.; Rabelink, T.J. & Teng, Y.K.O. (2014), Belimumab after rituximab as maintenance therapy in lupus nephritis., Rheumatology.
- Stomp, W.; Krabben, A.; Heijde, D. van der; Huizinga, T.W.J.; Bloem, J.L.; Helm-van Mil, A.H.M. van der & Reijnierse, M. (2014), Are rheumatoid arthritis patients discernible from other early arthritis patients using 1.5T extremity magnetic resonance imaging? A large cross-sectional study., Journal of Rheumatology 41(8): 1630-7.
- Markusse, I.M.; Dirven, L.; Broek, M. van den; Bijkerk, C.; Han, K.H.; Ronday, H.K.; Bolce, R.; Sasso, E.H.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2014), A Multibiomarker Disease Activity Score for Rheumatoid Arthritis Predicts Radiographic Joint Damage in the BeSt Study., Journal of Rheumatology.
- Gaalen, F.A. van; Verduijn, W.; Roelen, D.L.; Huizinga, T.W.J.; Heijde, D. van der & Toes, R.E.M. (2014), HLA-B60 and the HLA-B27/HLA-B60 genotype are not risk factors for acute anterior uveitis, Annals of the Rheumatic Diseases 73(3): 633-634.
- Kortekaas, M.C.; Kwok, W.Y.; Reijnierse, M.; Huizinga, T.W.J. & Kloppenburg, M. (2014), Follow-up study of inflammatory ultrasound features in hand osteoarthritis over a period of 3 months: variable as well as constant, Osteoarthritis and Cartilage 22(1): 40-43.
- Bijsterbosch, J.; Meulenbelt, I.; Watt, I.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2014), Clustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee, Annals of the Rheumatic Diseases 73(3): 567-572.
- Shi, J.; Veelen, P.A. van; Mahler, M.; Janssen, G.M.C.; Drijfhout, J.W.; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2014), Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies, Autoimmunity Reviews 13(3): 225-230.
- Zirkzee, E.J.M.; Huizinga, T.W.J.; Bollen, E.L.E.M.; Buchem, M.A. van; Middelkoop, H.A.M.; Wee, N.J.A. van der; Cessie, S. le & Steup-Beekman, G.M. (2014), Mortality in neuropsychiatric systemic lupus erythematosus (NPSLE), Lupus 23(1): 31-38.
- Meijs, J.; Vries, J. de; Ajmone, N.; Ninaber, M.; Huizinga, T. & Schouffoer, A. (2014), MINIMAL CLINICALLY IMPORTANT INVESTIGATIONS IN SYSTEMIC SCLEROSIS, Clinical and Experimental Rheumatology 32(2): S79-S79.
- Rombouts, Y.; Willemze, A.; Beers, J.J.B.C. van; Shi, J.; Kerkman, P.F.; Janssen, G.M.C.; Veelen, P.A. van; Zaldumbide, A.; Hoeben, R.C.; Pruijn, G.J.; Deelder, A.M.; Wolbink, G.; Rispens, T.; Garcia-Vallejo, J.J.; Kooyk, Y. van; Huizinga, T.W.J.; Wuhrer, M.; Trouw, L.A.; Scherer, H.U. & Toes, R.E.M. (2014), HYPERGLYCOSYLATION OF ACPA-IGG VARIABLE DOMAINS MODULATES REACTIVITY TO CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 73: A19-A19.
- Wang, J.; Balog, C.I.; Stavenhagen, K.; Koeleman, C.A.; Selman, M.H.; Deelder, A.M.; Huizinga, T.W.; Toes, R.E.; Wuhrer, M. & Scherer, H.U. (2013), MODULATING FC-LINKED GLYCOSYLATION PATTERNS OF HUMAN IGG1, Annals of the Rheumatic Diseases 71: 312-312.
- Rooy, D. de; Yeremenko, N.; Knevel, R.; Brouwer, E.; Wilson, G.; Lindqvist, E.; Saxne, T.; Krabben, A.; Leijsma, M.; Tsonaka, R.; Daha, N.; Zhernakova, S.; Houwing-Duistermaat, J.; Huizinga, T.; Baeten, D.; Toes, R. & Helm-van Mil, A. van der (2013), GENETIC STUDIES ON DICKKOPF-1, SCLEROSTIN AND THE SEVERITY OF JOINT DESTRUCTION IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: 83-83.
- Knevel, R.; Rooy, D. de; Zhernakova, S.; Grondal, G.; Krabben, A.; Steinsson, K.; Cavet, G.; Toes, R.; Huizinga, T.; Gregersen, P. & Helm-van Mil, A. van der (2013), GENETIC VARIANCE IN IL2RA ASSOCIATES WITH PROGRESSION OF JOINT DESTRUCTION AND CIRCULATING SIL-2RA LEVELS IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: 126-126.
- Kwok, K.Y.; Knevel, R.; Rooy, D.P. de; Posthumus, M.D.; Huizinga, T.W.; Brouwer, E. & Helm-van Mil, A.H. van der (2013), RADIOGRAPHING ONE HAND, ONE FOOT OR BOTH HANDS AND FEET IN RHEUMATOID ARTHRITIS, DOES IT MAKE A DIFFERENCE?, Annals of the Rheumatic Diseases 71: 337-337.
- Krabben, A.; Knevel, R.; Huizinga, T.W.J.; Cavet, G. & Helm-van Mil, A.H.M. van der (2013), SERUM PYRIDINOLINE LEVELS PREDICT THE SEVERITY OF FUTURE JOINT DESTRUCTION IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: 160-160.
- Rooy, D. de; Andersson, M.; Knevel, R.; Huizinga, T.; Svensson, B. & Helm-van Mil, A. van der (2013), DOES THE SEASON OF SYMPTOM ONSET INFLUENCE THE SEVERITY OF RADIOGRAPHIC JOINT DESTRUCTION IN RHEUMATOID ARTHRITIS?, Annals of the Rheumatic Diseases 71: 499-499.
- Hirata, S.; Dirven, L.; Shen, Y.J.; Centola, M.; Cavet, G.; Lems, W.F.; Tanaka, Y.; Huizinga, T.W.J. & Allaart, C.F. (2013), A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study, Rheumatology 52(7): 1202-1207.
- Heimans, L.; Broek, M. van den; Cessie, S. le; Siegerink, B.; Riyazi, N.; Han, K.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2013), Association of High Body Mass Index With Decreased Treatment Response to Combination Therapy in Recent-Onset Rheumatoid Arthritis Patients.
- Kerkman, P.F.; Rombouts, Y.; Voort, E.I.H. van der; Trouw, L.A.; Huizinga, T.W.J.; Toes, R.E.M. & Scherer, H.U. (2013), SPONTANEOUS PRODUCTION OF ANTI-CITRULLINATED PROTEIN ANTIBODIES IN CULTURES OF PERIPHERAL BLOOD MONONUCLEAR CELLS AND SYNOVIAL FLUID MONONUCLEAR CELLS ISOLATED FROM PATIENTS WITH RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 72: A41-A41.
- Helm-van Mil, A. van der & Huizinga, T. (2013), Prediction of Disease Outcome in Early Arthritis, Aktuelle Rheumatologie 38(1): 30-36.
- Woude, D. van der; Scherer, H.U.; Huizinga, T.W.J. & Toes, R.E.M. (2013), Pathogenic relevance of anti-citrullinated vimentin antibodies: comment on the article by Montes et al, Arthritis and Rheumatism 65(2): 541-542.
- Wevers-De Boer, K.V.C.; Heimans, L.; Huizinga, T. & Allaart, C. (2013), Drug therapy in undifferentiated arthritis: a systematic literature review, Annals of the Rheumatic Diseases 72(9): 1436-1444.
- Mirkov, M.U.; Cui, J.; Vermeulen, S.H.; Stahl, E.A.; Toonen, E.J.M.; Makkinje, R.R.; Lee, A.T.; Huizinga, T.W.J.; Allaart, R.; Barton, A.; Mariette, X.; Miceli, C.R.; Criswell, L.A.; Tak, P.P.; Vries, N. de; Saevarsdottir, S.; Padyukov, L.; Bridges, S.L.; Schaardenburg, D.J. van; Jansen, T.L.; Dutmer, E.A.J.; Laar, M.A.F.J.V. de; Barrera, P.; Radstake, T.R.D.J.; Riel, P.L.C.M. van; Scheffer, H.; Franke, B.; Brunner, H.G.; Plenge, R.M.; Gregersen, P.K.; Guchelaar, H.J. & Coenen, M.J.H. (2013), Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 72(8): 1375-1381.
- Broek, M. van den; Visser, K.; Allaart, C.F. & Huizinga, T.W.J. (2013), Personalized medicine: predicting responses to therapy in patients with RA, Current Opinion in Pharmacology 13(3): 463-469.
- Helm-van Mil, A.H.M. van der; Knevel, R.; Cavet, G.; Huizinga, T.W.J. & Haney, D.J. (2013), An evaluation of molecular and clinical remission in rheumatoid arthritis by assessing radiographic progression, Rheumatology 52(5): 839-846.
- Knevel, R.; Krabben, A.; Wilson, A.G.; Brouwer, E.; Leijsma, M.K.; Lindqvist, E.; Rooy, D.P.C. de; Daha, N.A.; Linden, M.P.M. van der; Tsonaka, S.; Zhernakova, A.; Westra, H.J.; Franke, L.; Houwing-Duistermaat, J.J.; Toes, R.E.M.; Huizinga, T.W.J.; Saxne, T. & Helm-van Mil, A.H.M. van der (2013), A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis, Arthritis and Rheumatism 65(3): 582-589.
- Bijsterbosch, J.; Kloppenburg, M.; Reijnierse, M.; Rosendaal, F.R.; Huizinga, T.W.J.; Slagboom, P.E. & Meulenbelt, I. (2013), Association study of candidate genes for the progression of hand osteoarthritis, Osteoarthritis and Cartilage 21(4): 565-569.
- Krabben, A.; Stomp, W.; Heijde, D.M.F.M. van der; Nies, J. van; Bloem, J.L.; Huizinga, T.W.J.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2013), MAGNETIC RESONANCE IMAGING OF HAND AND FOOT JOINTS OF PATIENTS WITH ACPA POSITIVE ARTHRALGIA WITHOUT CLINICAL ARTHRITIS, Annals of the Rheumatic Diseases 72: A3-A3.
- Markusse, I.M.; Akdemir, G.; Broek, M. van den; Dirven, L.; Goekoop, R.J.; Han, K.H.; Oosterhout, M. van; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Allaart, C.F. (2013), 10 Years Of Treat-To-Target Therapy In Rheumatoid Arthritis Patients (the BeSt study): Clinical and Radiological Outcomes, Arthritis and Rheumatism 65: S620-S620.
- Ioan-Facsinay, A.; Kwekkeboom, J.C.; Westhoff, S.; Giera, M.; Rombouts, Y.; Harmelen, V. van; Huizinga, T.W.J.; Deelder, A.; Kloppenburg, M. & Toes, R.E.M. (2013), Adipocyte-derived lipids modulate CD4(+) T-cell function, European Journal of Immunology 43(6): 1578-1587.
- Klein-Wieringa, I.R.; Andersen, S.N.; Kwekkeboom, J.C.; Giera, M.; Lange-Brokaar, B.J.E. de; Osch, G.J.V.M. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Nelissen, R.G.H.H.; Pijl, H.; Huizinga, T.W.J.; Kloppenburg, M.; Toes, R.E.M. & Ioan-Facsinay, A. (2013), Adipocytes Modulate the Phenotype of Human Macrophages through Secreted Lipids, Journal of Immunology 191(3): 1356-1363.
- Bossini-Castillo, L.; Kovel, C. de; Kallberg, H.; Coenen, M.J.H.; Tak, P.P.; Posthumus, M.D.; Wijmenga, C.; Huizinga, T.W.J.; Helm-van Mil,AHM van der; Rodriguez-Rodriguez, L.; Gonzalez-Alvaro, I.; Gonzalez-Gay, M.A.; Horst-Bruinsma, I.E. van der; Dijkmans, B.A.C.; Wolbink, G.J.; Ophoff, R.A.; Riel, P.L.C.M. van; Klareskog, L.; Crusius, J.B.A.; Brouwer, E.; Martin, J.; Vries, N. de; Toes, R.E.M.; Padyukov, L. & Koeleman, B.P.C. (2013), A Genome Wide Association Study Of Rheumatoid Arthritis Without Antibodies Against Citrullinated Peptides, Arthritis and Rheumatism 65: S343-S343.
- Teare, M.D.; Knevel, R.; Morgan, M.D.; Kleszcz, A.; Emery, P.; Moore, D.J.; Conaghan, P.; Huizinga, T.W.J.; Morgan, A.W.; Helm-van Mil, A.H.M. van der & Wilson, A.G. (2013), Allele-Dose Association of the C5orf30 rs26232 Variant With Joint Damage in Rheumatoid Arthritis, Arthritis and Rheumatism 65(10): 2555-2561.
- Markusse, I.M.; Dirven, L.; Broek, M. van den; Han, K.H.; Lieshout, M.F. van; Riyazi, N.; Bolce, R.J.; Sasso, E.H.; Kerstens, P.J.S.M.; Lems, W.F.; Huizinga, T.W.J. & Bolce, R.J. (2013), A Multi-Biomarker Disease Activity Score For Rheumatoid Arthritis Predicts Radiographic Damage In The BeSt Study, Arthritis and Rheumatism 65: S569-S569.
- Berg, R. van den; Hooge, M. de; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2013), Percentage of patients with spondyloarthritis in patients referred because of chronic back pain and performance of classification criteria: experience from the Spondyloarthritis Caught Early (SPACE) cohort, Rheumatology 52(8): 1492-1499.
- Hooge, M. de; Berg, R. van den; Navarro-Compan, V.; Gaalen, F. van; Heijde, D. van der; Huizinga, T. & Reijnierse, M. (2013), Magnetic resonance imaging of the sacroiliac joints in the early detection of spondyloarthritis: no added value of gadolinium compared with short tau inversion recovery sequence, Rheumatology 52(7): 1220-1224.
- Beekhuizen, M.; Gierman, L.M.; Spil, W.E. van; Osch, G.J.V.M. van; Huizinga, T.W.J.; Saris, D.B.F.; Creemers, L.B. & Zuurmond, A.M. (2013), An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid, Osteoarthritis and Cartilage 21(7): 918-922.
- Dougados, M.; Kissel, K.; Sheeran, T.; Tak, P.P.; Conaghan, P.G.; Mola, E.M.; Schett, G.; Amital, H.; Navarro-Sarabia, F.; Hou, A.; Bernasconi, C. & Huizinga, T.W.J. (2013), Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY), Annals of the Rheumatic Diseases 72(1): 43-50.
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- Klein-Wieringa, I.R.; Andersen, S.N.; Kwekkeboom, J.C.; Herb-van Toorn, L.; Helm-van Mil, A. van der; Meulenbelt, I.; Huizinga, T.J.; Kloppenburg, M.; Toes, R.E. & Ioan-Facsinay, A. (2013), DO HIGH MOLECULAR WEIGHT ADIPONECTIN LEVELS ASSOCIATE WITH RADIOGRAPHIC PROGRESSION IN EARLY RHEUMATIOD ARTHRITIS AND HAND OSTEOARTHRITIS?, Osteoarthritis and Cartilage 21: S136-S136.
- Plenge, R.M.; Greenberg, J.D.; Mangravite, L.M.; Derry, J.M.J.; Stahl, E.A.; Coenen, M.J.H.; Barton, A.; Padyukov, L.; Klareskog, L.; Gregersen, P.K.; Mariette, X.; Moreland, L.W.; Bridges, S.L.; Vries, N. de; Huizinga, T.W.J.; Guchelaar, H.J.; Friend, S.H.; Stolovitzky, G. & Int Rheumatoid Arthritis (2013), Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge, Nature Genetics 45(5): 468-469.
- Shi, J.; Stadt, L.A. van de; Levarht, E.W.N.; Huizinga, T.W.J.; Toes, R.E.M.; Trouw, L.A. & Schaardenburg, D. van (2013), Brief Report: AntiCarbamylated Protein Antibodies Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis, Arthritis and Rheumatism 65(4): 911-915.
- Koevoets, R.; Glas, N.A. de; Bourlout, C. le; Huizinga, T.W.J.; Allaart, C.F.; Dougados, M. & Gossec, L. (2013), Autonomous online health assessment questionnaire registry in daily clinical practice, Rheumatology 52(5): 883-887.
- Rooy, D.P.C. de; Zhernakova, A.; Tsonaka, R.; Willemze, A.; Kurreeman, B.A.S.; Toes, R.E.M.; Huizinga, T.W.J.; Houwing-Duistermaat, J.J.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2013), A GENETIC VARIANT IN THE REGION OF MMP-9 IS ASSOCIATED WITH SERUM LEVELS AND PROGRESSION OF JOINT DAMAGE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 72: A48-A48.
- Lange-Brokaar, B. de; Ioan-Facsinay, A.; Yusuf, E.; Visser, W.; Kroon, H.; Osch, G. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Bloem, J.; Nelissen, R.; Huizinga, T. & Kloppenburg, M. (2013), DIFFERENT PATTERNS OF SYNOVITIS AS SEEN ON CE-MRI IN PATIENTS WITH KNEE OSTEOARTHRITIS, Osteoarthritis and Cartilage 21: S16-S16.
- Ioan-Facsinay, A.; Kwekkeboom, J.C.; Westhoff, S.; Giera, M.; Rombouts, Y.; Huizinga, T.W.J.; Deelder, A.; Kloppenburg, M. & Toes, R.E.M. (2013), ADIPOCYTES MODULATE T CELL FUNCTION THROUGH RELEASE OF LIPIDS, Annals of the Rheumatic Diseases 72: A24-A24.
- Klein-Wieringa, I.R.; Andersen, S.N.; Kwekkeboom, J.C.; Giera, M.; Lange-Brokaar, B.J.E. de; Osch, G.J.V.M. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Nelissen, R.G.H.H.; Huizinga, T.W.J.; Kloppenburg, M.; Toes, R.E.M. & Ioan-Facsinay, A. (2013), Adipocytes Modulate the Phenotype of Macrophages Through Secreted Lipids, Annals of the Rheumatic Diseases 72: A24-A24.
- Berg, R. van den; Hooge, M. de; Reijnierse, M.; Compan, V.N.; Fagerli, K.; Turina, M.; Oosterhout, M. van; Ramonda, R.; Gaalen, F. van; Huizinga, T. & Heijde, D. van der (2013), INFLAMMATION IN THE POSTERIOR ELEMENTS OF THE SPINE IS INFREQUENT IN PATIENTS WITH RECENT ONSET AXIAL SPONDYLOARTHRITIS, ESPECIALLY IF NO INFLAMMATION IN THE VERTEBRAL BODIES IS OBSERVED, Annals of the Rheumatic Diseases 72: 663-664.
- Hooge, M. de; Berg, R. van den; Compan, M.V.N.; Reijnierse, M.; Gaalen, F. van; Fagerli, K.M.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T. & Heijde, D. van der (2013), DO BONE MARROW EDEMA (BME) LESIONS IN THE SACROILIAC JOINT (SW) CHANGE INTO FATTY LESIONS OVER A 3-MONTH PERIOD IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS (AXSPA)?, Annals of the Rheumatic Diseases 72: 656-657.
- Brakenhoff, L.; Berg, R. van den; Gaalen, F. van; Meulen-de Jong, A. van der; Huizinga, T.; Hommes, D.; Heijde, D. van der & Fidder, H. (2013), BACK PAIN AND PERIPHERAL JOINT COMPLAINTS IN INFLAMMATORY BOWEL DISEASE PATIENTS, Annals of the Rheumatic Diseases 72: 532-533.
- Checa, C.M.; Cohen, D.; Bollen, E.L.E.M.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2013), Demyelinating disease in SLE: Is it multiple sclerosis or lupus?, Best Practice and Research: Clinical Rheumatology 27(3).
- Boumans, M.; Teng, O.; Thurlings, R.; Bijlsma, J.; Gerlag, D.; Huizinga, T.; Vos, K.; Stapel, S.; Wolbink, G.; Tekstra, J.; Laar, J. van & Tak, P.P. (2013), Progression of structural damage is not related to rituximab serum levels in rheumatoid arthritis patients, Rheumatology 52(8): 1462-1466.
- Liu, B.S.; Stoop, J.N.; Huizinga, T.W. & Toes, R.E.M. (2013), IL-21 Enhances the Activity of the TLR-MyD88-STAT3 Pathway but Not the Classical TLR-MyD88-NF-kappa B Pathway in Human B Cells To Boost Antibody Production, Journal of Immunology 191(8): 4086-4094.
- Gierman, L.M.; Kuhnast, S.; Koudijs, A.; Pieterman, E.J.; Kloppenburg, M.; Osch, G.J. van; Stojanovic-Susulic, V.; Huizinga, T.W.; Princen, H.M. & Zuurmond, A.M. (2013), OSTEOARTHRITIS DEVELOPMENT IS INDUCED BY INCREASED DIETARY CHOLESTEROL IN APOE*3LEIDEN.CETP MICE, A TRANSLATIONAL MODEL FOR ATHEROSCLEROSIS, AND CAN BE INHIBITED BY ATORVASTATIN, Osteoarthritis and Cartilage 21: S65-S66.
- Berg, R. van den; Hooge, M. de; Gaalen, F. van; Compan, V.N.; Reijnierse, M.; Fagerli, K.; Landewe, R.; Oosterhout, M. van; Punzi, L.; Huizinga, T. & Heijde, D. van der (2013), INFLUENCE OF TAKING STRUCTURAL LESIONS INTO ACCOUNT IN ADDITION TO INFLAMMATORY LESIONS ON MRI OF THE SACROILIAC JOINTS ON THE CLASSIFICATION OF PATIENTS WITH POSSIBLE AXIAL SPONDYLOARTHRITIS, Annals of the Rheumatic Diseases 72: 664-664.
- Heimans, L.; Wevers-de Boer, K.V.C.; Koudijs, K.K.M.; Visser, K.; Goekoop-Ruiterman, Y.P.; Harbers, J.B.; Steup-Beekman, G.M.; Lard, L.R.; Grillet, B.A.M.; Huizinga, T.W.J. & Allaart, C.F. (2013), Health-related quality of life and functional ability in patients with early arthritis during remission steered treatment: results of the IMPROVED study.
- Checa, C.M.; Cohen, D.; Bollen, E.L.E.M.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2013), Demyelinating disease in SLE: Is it multiple sclerosis or lupus?, Best Practice and Research: Clinical Rheumatology 27(3): 405-424.
- Buckley, F.; Finckh, A.; Huizinga, T.W.; Dejonckheere, F. & Jansen, J.P. (2013), COMPARATIVE EFFICACY OF BIOLOGICS AS MONOTHERAPY AND IN COMBINATION WITH METHOTREXATE IN RHEUMATOID ARTHRITIS PATIENTS WITH AN INADEQUATE RESPONSE TO CONVENTIONAL DMARDS: A NETWORK META-ANALYSIS, Rheumatology 52: 93-93.
- Steenbergen, H.W. van; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2013), The Preclinical Phase of Rheumatoid Arthritis: What Is Acknowledged and What Needs to be Assessed?, Arthritis and Rheumatism 65(9): 2219-2232.
- Krabben, A.; Stomp, W.; Nies, J.A.B. van; Huizinga, T.W.J.; Heijde, D. van der; Bloem, J.L.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2013), Radiological Outcome Of Joints With MRI Detected Subclinical Inflammation In Early Arthritis Patients, Arthritis and Rheumatism 65: S1200-S1200.
- Habets, K.L.L.; Huizinga, T.W.J. & Toes, R.E.M. (2013), Platelets and autoimmunity, European Journal of Clinical Investigation 43(7): 746-757.
- Gierman, L.M.; Wopereis, S.; , B. van el; Verheij, E.R.; Werff-van der Vat, B.J.C.; Bastiaansen-Jenniskens, Y.M.; Osch, G.J.V.M. van; Kloppenburg, M.; Stojanovic-Susulic, V.; Huizinga, T.W.J. & Zuurmond, A.M. (2013), Metabolic Profiling Reveals Differences in Concentrations of Oxylipins and Fatty Acids Secreted by the Infrapatellar Fat Pad of Donors With End-Stage Osteoarthritis and Normal Donors, Arthritis and Rheumatism 65(10): 2606-2614.
- Huizinga, T.W.J.; Conaghan, P.G.; Martin-Mola, E.; Schett, G.; Amital, H.; Xavier, R.M.; Troum, O.; Aassi, M.; Bernasconi, C. & Dougados, M. (2013), Clinical and Radiographic Outcomes At Two Years and The Effect Of Tocilizumab Discontinuation Following Sustained Remission In The Second Year Of The ACT-RAY Study., Arthritis and Rheumatism 65: S609-S609.
- Knevel, R.; Tsonaka, R.; Cessie, S. le; Linden, M.P.M. van der; Huizinga, T.W.J.; Heijde, D.M.F.M. van der; Houwing-Duistermaat, J.J. & Helm-van Mil, A.H.M. van der (2013), Comparison of methodologies for analysing the progression of joint destruction in rheumatoid arthritis, Scandinavian Journal of Rheumatology 42(3): 182-189.
- Trouw, L.A.; Huizinga, T.W.J. & Toes, R.E.M. (2013), Autoimmunity in rheumatoid arthritis: different antigens-common principles, Annals of the Rheumatic Diseases 72: 132-136.
- Steup-Beekman, G.M.; Zirkzee, E.J.M.; Cohen, D.; Gahrmann, B.M.A.; Emmer, B.J.; Steens, S.C.A.; Bollen, E.L.E.M.; Buchem, M.A. van & Huizinga, T.W.J. (2013), Neuropsychiatric manifestations in patients with systemic lupus erythematosus: epidemiology and radiology pointing to an immune-mediated cause, Annals of the Rheumatic Diseases 72: 76-79.
- Daleboudt, G.M.N.; Reinders, M.E.J.; Hartigh, J. den; Huizinga, T.W.J.; Rabelink, A.J.; Fijter, J.W. de & Berger, S.P. (2013), Concentration-controlled treatment of lupus nephritis with mycophenolate mofetil, Lupus 22(2): 171-179.
- Suurmond, J.; Heemst, J. van; Heiningen, J. van; Dorjee, A.L.; Schilham, M.W.; Beek, F.B. van der; Huizinga, T.W.J.; Schuerwegh, A.J.M. & Toes, R.E.M. (2013), Communication between human mast cells and CD4(+) T cells through antigen-dependent interactions, European Journal of Immunology 43(7): 1758-1768.
- Vries-Bouwstra, J.K. de; Burgel, N.D. van; Vreeswijk, T.; Kroes, A.C.M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2013), Prevalence and Clinical Presentation Of Lyme Arthritis In a Large Cohort Of Patients With Recent-Onset Arthritis, Arthritis and Rheumatism 65: S1202-S1203.
- Emery, P.; Sebba, A. & Huizinga, T.W.J. (2013), Biologic and oral disease-modifying antirheumatic drug monotherapy in rheumatoid arthritis, Annals of the Rheumatic Diseases 72(12): 1897-1904.
- Muller, P.C.E.H.; Anink, J.; Shi, J.; Levarht, E.W.N.; Reinards, T.H.C.M.; Otten, M.H.; Tol, M.J.D. van; Jol-van der Zijde, C.M.; Brinkman, D.M.C.; Allaart, C.F.; Hoppenreijs, E.P.; Koopman-Keemink, Y.; Kamphuis, S.S.M.; Dolman, K.; Berg, J.M. van den; Rossum, M.A.J. van; Suijlekom-Smit, L.W.A. van; Schilham, M.W.; Huizinga, T.W.J.; Toes, R.E.M.; Cate, R. ten & Trouw, L.A. (2013), Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients, Annals of the Rheumatic Diseases 72(12): 2053-2055.
- Berg, R. van den; Hooge, M. de; Compan, V.N.; Reijnierse, M.; Gaalen, F. van; Fagerli, K.; Landewe, R.; Oosterhout, M. van; Ramonda, R.; Huizinga, T. & Heijde, D. van der (2013), VOLATILITY OF THE SITE AND TYPE OF LESIONS IN THE SPINE IN PATIENTS WITH RECENT ONSET SPONDYLOARTHRITIS AND POSSIBLE SPONDYLOARTHRITIS OVER A 3-MONTH PERIOD, Annals of the Rheumatic Diseases 72: 663-663.
- Liu, B.; Huizinga, T. & Toes, R. (2013), TLR7/8 agonists and type I IFN induce the differentiation of human IL-10-producing B cells into antibody-producing B cells via the TLR-MyD88-STAT(3) pathway, Immunology 140: 61-61.
- Liu, B.; Stoop, J.N.; Huizinga, T.W. & Toes, R. (2013), IL-21 synergistically enhances TLR-MyD88-STAT3 pathway but not the conventional TLR-MyD88-NF-kappa B pathway in human B cells, resulted in increased antibody production, Immunology 140: 63-63.
- Heimans, L.; Wevers-de Boer, K.; Visser, K.; Ronday, H.K.; Steup-Beekman, G.M.; Oosterhout, M. van; Huizinga, T.W.J.; Giltay, E.J.; Mast, R.C. van der & Allaart, C.F. (2013), The relationship between disease activity and depressive symptoms severity and optimism-results from the IMPROVED study, Clinical Rheumatology 32(12): 1751-1757.
- Krabben, A.; Wilson, A.G.; Rooy, D.P.C. de; Zhernakova, A.; Brouwer, E.; Lindqvist, E.; Saxne, T.; Stoeken, G.; Nies, J.A.B. van; Knevel, R.; Huizinga, T.W.J.; Toes, R.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2013), Association of Genetic Variants in the IL4 and IL4R Genes With the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts, Arthritis and Rheumatism 65(12): 3051-3057.
- Hooge, M. de; Berg, R. van den; Gaalen, F. van; Compan, M.V.N.; Reijnierse, M.; Fagerli, K.M.; Turina, M.; Oosterhout, M. van; Lorenzin, M.; Huizinga, T. & Heijde, D. van der (2013), IS SITE OF BACK PAIN RELATED TO LOCATION OF INFLAMMATORY LESIONS ON MRI IN PATIENTS WITH CHRONIC BACK PAIN?, Annals of the Rheumatic Diseases 72: 127-127.
- Li, W.; Helm-van Mil, A. van der; Knevel, R.; Cavet, G.; Huizinga, T. & Haney, D. (2013), BIOMARKER-BASED ESTIMATES OF RISK OF RADIOGRAPHIC PROGRESSION IN THE LEIDEN EARLY ARTHRITIS COHORT, Annals of the Rheumatic Diseases 72: 403-403.
- Huizinga, T.W.J.; Donka, T.; Conaghan, P.G.; Martin-Mola, E.; Schett, G.; Amital, H.; Xavier, R.M.; Troum, O.; Bernasconi, C. & Dougados, M. (2013), CLINICAL AND RADIOGRAPHIC OUTCOMES AT TWO YEARS AND THE EFFECT OF TOCILIZUMAB (TCZ) DISCONTINUATION FOLLOWING SUSTAINED REMISSION IN THE SECOND YEAR OF THE ACT-RAY STUDY, Annals of the Rheumatic Diseases 72: 63-63.
- Krabben, A.; Stomp, W.; Huizinga, T.W.J.; Heijde, D.M.F.M. van der; Bloem, H.L.; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2013), CONCORDANCE BETWEEN JOINT SWELLING OR TENDERNESS AT PHYSICAL EXAMINATION AND INFLAMMATION ON MRI IN EARLY ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 72: 111-111.
- Lange-Brokaar, B.J.E. de; Ioan-Facsinay, A.; Yusuf, E.; Visser, A.W.; Kroon, H.M.; Osch, G.J.V.M. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Bloem, J.L.; Nelissen, R.G.H.H.; Huizinga, T.W.J. & Kloppenburg, M. (2013), DIFFERENT PATTERNS OF SYNOVITIS PRESENT IN OA PATIENTS ASSOCIATE DIFFERENTIALLY WITH PAIN, Annals of the Rheumatic Diseases 72: 56-56.
- Klein-Wieringa, I.; Andersen, S.; Herb-van Toorn, L.; Kwekkeboom, J.; Helm-van Mil, A.; Meulenbelt, I.; Huizinga, T.; Kloppenburg, M.; Toes, R. & Loan-Facsinay, A. (2013), DO HIGH MOLECULAR WEIGHT ADIPONECTIN LEVELS ASSOCIATE WITH RADIOGRAPHIC PROGRESSION IN RHEUMATOID ARTHRITIS AND HAND OSTEOARTHRITIS?, Annals of the Rheumatic Diseases 72: 202-203.
- Wevers-De Boer, K.V.C.; Heimans, L.; Visser, K.; Schouffoer, A.; Oosterhout, M. van; Groenendaal, H. van; Speyer, I.; Huizinga, T. & Allaart, C. (2013), DRUG FREE REMISSION AFTER ONE YEAR OF TREATMENT IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS: ALSO POSSIBLE FOR ACPA POSITIVE PATIENTS?, Annals of the Rheumatic Diseases 72: 114-114.
- Wevers-De Boer, K.V.C.; Heimans, L.; Visser, K.; Kalvesten, J.; Goekoop, R.; Molenaar, E.; Buck, M. de; Huizinga, T. & Allaart, C. (2013), EARLY METACARPAL BONE MINERAL DENSITY LOSS IS PREDICTIVE FOR RADIOLOGIC JOINT DAMAGE PROGRESSION AFTER 1 YEAR IN PATIENTS WITH EARLY ARTHRITIS, Annals of the Rheumatic Diseases 72: 549-549.
- Rooy, D. de; Tsonaka, R.; Andersson, M.; Forslind, K.; Zhernakova, A.; Kovel, C. de; Koeleman, B.; Heijde, D. van der; Huizinga, T.; Toes, R.; Houwing-Duistermaat, J.; Svensson, B. & Helm-van Mil, A. van der (2013), GENETIC FACTORS FOR THE SEVERITY OF ACPA-NEGATIVE RHEUMATOID ARTHRITIS IN TWO COHORTS OF EARLY DISEASE: A GENOME-WIDE STUDY, Annals of the Rheumatic Diseases 72: 55-55.
- Visser, W.; Heijer, M. den; Spoelman, W.; Rosendaal, F.R.; Huizinga, T.W. & Kloppenburg, M. (2013), GLUCOSE AND INSULIN CONCENTRATIONS IN ASSOCIATION WITH HAND OSTEOARTHRITIS: THE NEO STUDY, Annals of the Rheumatic Diseases 72: 702-702.
- Ferraccioli, G.; Lapadula, G.; Dougados, M.; Veale, D.J.; Huizinga, T.W.; Allaart, C.F.; Landewe, R.B.; Silva, J.A.P. da; Mola, E.M.; Moots, R.J.; Kay, J.; Salomon-Escoto, K.I. & Heijde, D. van der (2013), HAQ BASELINE VALUES IN AN INTERNATIONAL REGISTRY OF RA PATIENTS DURING THE ERA OF BIOLOGIC TERAPIES: THE 2013 METEOR DATABASE., Annals of the Rheumatic Diseases 72: 402-402.
- Meijs, J.; Zirkzee, E.; Schouffoer, A.; Henquet, S.; Caljouw, M.; Stijnen, T.; Huizinga, T.; Schuerwegh, A. & Vliet-Vlieland, T. (2013), HEALTH CARE UTILIZATION IN DUTCH SYSTEMIC SCLEROSIS PATIENTS, Annals of the Rheumatic Diseases 72: 1026-1026.
- Liu, R.; Huizinga, T.W. & Kloppenburg, M. (2013), MORTALITY IN OSTEOARTHRITIS : A SYSTEMATIC REVIEW, Annals of the Rheumatic Diseases 72: 699-699.
- Vollenhoven, R.F. van; Mild, M.; Dorner, T.; Gremese, E.; Houssiau, F.; Huizinga, T.; Isenberg, D.A.; Kovacs, L.; Ruiz-Irastorza, G.; Squatrito, D.; Emmi, L.; Voskuyl, A.; Mosca, M.; Castro, A.; Iuliano, A.; Inanc, M.; Szucs, G.; Doria, A.; Jacobsen, S. & IRBIS-EMA Study Grp (2013), OFF-LABEL USE OF RITUXIMAB FOR SLE IN EUROPE: A COMPARISON TO PATIENTS TREATED WITH CONVENTIONAL IMMUNOSUPPRESSIVE MEDICATIONS, Annals of the Rheumatic Diseases 72: 254-254.
- Heimans, L.; Wevers-de Boer, K.V.; Visser, K.; Goekoop-Ruiterman, Y.P.; Molenaar, T.H.; Harbers, J.B.; Bijkerk, C.; Speyer, I.; Buck, P.D. de; Sonnaville, P.B. de; Grillet, B.A.; Huizinga, T.W. & Allaart, C.F. (2013), OUTCOMES OF TWO YEARS OF REMISSION STEERED TREATMENT IN EARLY ARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 72: 401-401.
- Berg, R. van den; Hooge, M. de; Compan, V.N.; Reijnierse, M.; Gaalen, F. van; Fagerli, K.; Landewe, R.; Oosterhout, M. van; Lorenzin, M.; Huizinga, T. & Heijde, D. van der (2013), PERFORMANCE OF MRI COMPARED TO CONVENTIONAL RADIOGRAPHS IN THE DETECTION OF STRUCTURAL LESIONS IN THE SACROILIAC JOINTS IN PATIENTS WITH RECENT ONSET AXIAL SPONDYLOARTHRITIS, Annals of the Rheumatic Diseases 72: 658-658.
- Hooge, M. de; Berg, R. van den; Reijnierse, M.; Compan, M.V.N.; Gaalen, F. van; Fagerli, K.M.; Turina, M.; Oosterhout, M. van; Ramonda, R.; Huizinga, T. & Heijde, D. van der (2013), PREVALENCE OF INFLAMMATORY LESIONS MRI-SPINE IN PATIENTS WITH CHRONIC BACK PAIN OF < 2 YEARS DURATION INCLUDED IN THE SPACE-COHORT, Annals of the Rheumatic Diseases 72: 660-661.
- Hooge, M. de; Berg, R. van den; Compan, V.N.; Reijnierse, M.; Gaalen, F. van; Fagerli, K.M.; Turina, M.; Oosterhout, M. van; Lorenzin, M.; Huizinga, T. & Heijde, D. van der (2013), PREVALENCE OF STRUCTURAL LESIONS MRI-SPINE IN PATIENTS WITH (POSSIBLE)AXIAL SPONDYLOARTHRITIS (AXSPA) INCLUDED IN THE SPACE-COHORT, Annals of the Rheumatic Diseases 72: 145-145.
- Berg, R. van den; Hooge, M. de; Compan, V.N.; Reijnierse, M.; Gaalen, F. van; Fagerli, K.; Turina, M.; Oosterhout, M. van; Punzi, L.; Huizinga, T. & Heijde, D. van der (2013), PREVALENCE OF STRUCTURAL LESIONS ON MRI OF THE SACROILIAC JOINTS IN PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS AND PATIENTS WITH BACK PAIN, Annals of the Rheumatic Diseases 72: 144-145.
- Hooge, M. de; Berg, R. van den; Gaalen, F. van; Reijnierse, M.; Compan, M.V.N.; Fagerli, K.M.; Turina, M.; Oosterhout, M. van; Punzi, L.; Huizinga, T. & Heijde, D. van der (2013), PREVALENCE OF SYNDESMOPHYTES IN PATIENTS WITH CHRONIC BACK PAIN SUSPECTED OF AXIAL SPONDYLOARTHRITIS (AXSPA) NOT FULFILLING THE MODIFIED NEW YORK (MNY) CRITERIA, Annals of the Rheumatic Diseases 72: 661-661.
- Navarro-Compan, V.; Smolen, J.; Huizinga, T.; Landewe, R. & Heijde, D. van der (2013), QUALITY INDICATORS (QIS) IN RHEUMATOID ARTHRITIS (RA) IN CLINICAL PRACTICE: RESULTS FROM MEASUREMENT OF EFFICACY OF TREATMENT IN THE ERA OF OUTCOME IN RHEUMATOLOGY (METEOR) DATABASE, Annals of the Rheumatic Diseases 72: 589-590.
- Broek, M. van den; Allaart, C.F.; Brines, M.; Cerami, A. & Huizinga, T.W. (2013), SAFETY AND EFFICACY OF ARA290, A NON-HEMATOPOIETIC ERYTHROPOIETIN DERIVED PEPTIDE, IN A 4 WEEKS PHASE II OPEN LABEL TRIAL IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 72: 620-620.
- Rooy, D. de; Nies, J. van; Andersson, M.; Forslind, K.; Heijde, D. van der; Huizinga, T.; Gregersen, P.; Svensson, B. & Helm-van Mil, A. van der (2013), SMOKING AS A RISK FACTOR FOR THE SEVERITY OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 72: 113-113.
- Muhammad, A.; Wesemael, T. van; Kochi, Y.; Mjaavatten, M.; Wevers-de Boer, K.; Allaart, C.; Trouw, L.; Suzuki, A.; Yamamoto, K.; Huizinga, T.; Toes, R. & Woude, D. van der (2013), SMOKING IS NOT PRIMARILY ASSOCIATED WITH ACPA, BUT WITH THE PRESENCE OF MULTIPLE AUTOANTIBODIES IN RA, Annals of the Rheumatic Diseases 72: 117-117.
- Huizinga, T.W.J.; Fleischmann, R.; Vollenhoven, R. van; Gruben, D.; Wilkinson, B.; Koncz, T.; Bradley, J.; Zwillich, S.H. & Benda, B. (2013), TOFACITINIB MONOTHERAPY IS EFFECTIVE IN METHOTREXATE-NAIVE PATIENTS WITH DISEASE DURATION LESS THAN 6 MONTHS: A POST-HOC ANALYSIS OF EARLY RHEUMATOID ARTHRITIS SUBJECTS IN A PHASE 3 TRIAL, Annals of the Rheumatic Diseases 72: 241-241.
- Shi, J.; Willemze, A.; Janssen, G.M.C.; Veelen, P.A. van; Drijfhout, J.W.; Cerami, A.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E. (2013), Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method, Annals of the Rheumatic Diseases 72(1): 148-150.
- Kwok, W.Y.; Plevier, J.W.M.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2013), Risk Factors for Progression in Hand Osteoarthritis: A Systematic Review.
- Huidekoper, A.L.; Woude, D. van der; Knevel, R.; Helm-van Mil, A.H.M. van der; Cannegieter, S.C.; Rosendaal, F.R.; Kloppenburg, M. & Huizinga, T.W.J. (2013), Patients with early arthritis consume less alcohol than controls, regardless of the type of arthritis, Rheumatology 52(9): 1701-1707.
- Scherer, H.U.; Rombouts, Y.; Ewing, E.; Stadt, L.A. van de; Selman, M.H.; Deelder, A.M.; Huizinga, T.W.; Wuhrer, M.; Schaardenburg, D. van & Toes, R.E. (2013), ANTI-CITRULLINATED PROTEIN ANTIBODY SPECIFIC FC GLYCOSYLATION PATTERNS IN PATIENTS WITH ARTHRALGIA, Annals of the Rheumatic Diseases 72: 116-117.
- Vries-Bouwstra, J.K. de; Huizinga, T.W.J.; Willems, L.N. & Helm-van Mil, A.H.M. van der (2012), Diagnostic value of performing chest x-rays in patients presenting with recent-onset arthritis, Annals of the Rheumatic Diseases 71(4): 627-U195.
- Bergen, J. van; Gaalen, F.A. van; Dongen, H. van; Huizinga, T.W.J.; Feltkamp, M.C.W.; Toes, R.E.M. & Koning, F. (2012), Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: Comment on the article by Pierer et al, Arthritis and Rheumatism 64(8): 2803-2804.
- Hooge, M. de; Berg, R. van den; Reijnierse, M.; Navarro-Compan, V.; Gaalen, F. van; Huizinga, T. & Heijde, D. van der (2012), Localisation of Bone Marrow Edema in Sacroiliac Joints in Spondyloarthritis Patients: Does the Site of Lesions Change Over a 3-Month Period?, Arthritis and Rheumatism 64(10): S1106-S1107.
- Hooge, M. de; Berg, R. van den; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), Almost 40% of Patients with Chronic Back Pain Starting Before the Age of 45 Fulfill the ASAS Axial Spondyloarthritis Criteria., Arthritis and Rheumatism 64(10): S245-S246.
- Berg, R. van den; Hooge, M. de; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), PATIENTS FULFILLING THE IMAGING-ARM AND PATIENTS FULFILLING THE HLA-B27-ARM OF THE ASAS AXIAL SPONDYLOARTHRITIS CLASSIFICATION CRITERIA: ARE THEY SIMILAR?, Clinical and Experimental Rheumatology 30(4): 612-612.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), HOW USEFUL IS IMAGING OF THE SI-JOINTS (MRI AND/OR X-RAY) IN PATIENTS WITH POSSIBLE SPONDYLOARTHRITIS IN THE DIAGNOSTIC WORK-UP?, Clinical and Experimental Rheumatology 30(4): 611-612.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), HOW MUCH DOES THE SPARCC-SCORE OF THE SI-JOINTS CHANGE OVER A 3-MONTH PERIOD IN PATIENTS ON NON-BIOLOGICAL TREATMENT?, Clinical and Experimental Rheumatology 30(4): 626-626.
- Hooge, M. de; Berg, R. van den; Navarro-Compan, V.; Gaalen, F. van; Heijde, D. van der; Huizinga, T. & Reijnierse, M. (2012), ASSESSING ACTIVE INFLAMMATION IN SACROILIAC JOINTS IN SPONDYLOARTHRITIS PATIENTS: NO ADDED VALUE OF GADOLINIUM COMPARED TO STIR SEQUENCE, Clinical and Experimental Rheumatology 30(4): 627-627.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Reijnierse, M.; Gaalen, F. van; Huizinga, T. & Heijde, D. van der (2012), A SPARCC-SCORE CUT-OFF >= 3 AS BEST MATCH FOR THE ASAS DEFINITION OF A POSITIVE MRI OF THE SACROILIAC JOINTS, Clinical and Experimental Rheumatology 30(4): 626-626.
- Jansen, D.T.S.L.; Daha, N.; Kurreeman, F.A.S.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W.; Toes, R.E.M. & Trouw, L.A. (2012), GENETIC VARIANTS OF C1Q ARE A RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 71: A54-A54.
- Willemze, A.; Bohringer, S.; Knevel, R.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2012), The ACPA recognition profile and subgrouping of ACPA-positive RA patients, Annals of the Rheumatic Diseases 71(2): 268-274.
- Weinblatt, M.E.; Fleischmann, R.; Huizinga, T.W.J.; Emery, P.; Pope, J.; Massarotti, E.M.; Vollenhoven, R.F. van; Wollenhaupt, J.; Bingham, C.O.; Duncan, B.; Goel, N.; Davies, O.R. & Dougados, M. (2012), Efficacy and safety of certolizumab pegol in a broad population of patients with active rheumatoid arthritis: results from the REALISTIC phase IIIb study, Rheumatology 51(12): 2204-2214.
- Behrens, F.; Ostergaard, M.; Stoilov, R.; Wiland, P.; Huizinga, T.W.; Berenfus, V.Y.; Tak, P.P.; Vladeva, S.; Rech, J.; Rubbert-Roth, A.; Korkosz, M.; Rekalov, D.; Zupanets, I.A.; Ejbjerg, B.J.; Geiseler, J.; Fresenius, J.; Korolkiewicz, R.P.; Schottelius, A.J. & Burkhardt, H. (2012), First in Patient Study of Anti-GM-CSF Monoclonal Antibody (MOR103) in Active Rheumatoid Arthritis: Results of a Phase 1b/2a Randomized, Double-Blind, Placebo-Controlled Trial., Arthritis and Rheumatism 64(12): 4171-4172.
- Beekhuizen, M.; Gierman, L.; Creemers, L.B.; Dhert, W.J.; Huizinga, T.W.; Osch, G.J. van & Zuurmond, A.M. (2012), A DESCRIPTIVE STUDY OF SYNOVIAL FLUID CHANGES IN CYTOKINE, CHEMOKINE AND GROWTH FACTOR LEVELS BETWEEN OSTEOARTHRITIS PATIENTS AND HEALTHY DONORS, Osteoarthritis and Cartilage 20: S79-S80.
- Lange-Brokaar, B.J. de; Ioan-Facsinay, A.; Visser, A.W.; Andersen, S.N.; Toorn, L. van; Osch, G.J. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Reijnierse, M.; Nelissen, R.G.; Huizinga, T.W. & Kloppenburg, M. (2012), DEGREE OF SYNOVITIS ON MRI IS CORRELATED WITH HISTOLOGICAL AND MACROSCOPIC FEATURES OF SYNOVIAL TISSUE INFLAMMATION IN KNEE OSTEOARTHRITIS, Annals of the Rheumatic Diseases 71: A90-A90.
- Zirkzee, E.J.M.; Steup-Beekman, G.M.; Mast, R.C. van der; Bollen, E.L.E.M.; Wee, N.J.A. van der; Baptist, E.; Slee, T.M.; Huisman, M.V.; Middelkoop, H.A.M.; Luyendijk, J.; Buchem, M.A. van & Huizinga, T.W.J. (2012), Prospective Study of Clinical Phenotypes in Neuropsychiatric Systemic Lupus Erythematosus; Multidisciplinary Approach to Diagnosis and Therapy.
- Koevoets, R.; Dirven, L.; Klarenbeek, N.B.; Krugten, M.V. van; Ronday, H.K.; Heijde, D.M.F.M. van der; Huizinga, T.W.J.; Kerstens, P.S.J.M.; Lems, W.F. & Allaart, C.F. (2012), 'Insights in the relationship of joint space narrowing versus erosive joint damage and physical functioning of patients with RA', Annals of the Rheumatic Diseases.
- Nies, J.A.B. van; Brouwer, E.; Gaalen, F.A. van; Allaart, C.F.; Huizinga, T.W.J.; Posthumus, M.D. & Helm-van Mil, A.H.M. van der (2012), Improved early identification of arthritis: evaluating the efficacy of Early Arthritis Recognition Clinics., Annals of the Rheumatic Diseases.
- Dirven, L.; Broek, M. van den; Kroon, H.M.; Grillet, B.A.M.; Han, K.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2012), Large-joint damage in patients with early rheumatoid arthritis and its association with treatment strategy and damage of the small joints., Rheumatology.
- Dirven, L.; Huizinga, T.W.J. & Allaart, C.F. (2012), Risk factors for reported influenza and influenza-like symptoms in patients with rheumatoid arthritis., Scandinavian Journal of Rheumatology 41(5): 359-65.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Reijnierse, M.; Gaalen, F. van; Huizinga, T. & Heijde, D. van der (2012), A Spondyloarthritis Research Consortium of Canada Score Cut-off >= 3 As Best Match for the Assessment of Spondyloarthritis International Society Definition of a Positive MRI of the Sacroiliac Joints., Arthritis and Rheumatism 64(10): S595-S595.
- Halff, E.F.; Diebolder, C.A.; Versteeg, M.; Schouten, A.; Brondijk, T.H.C. & Huizinga, E.G. (2012), Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin, Journal of Biological Chemistry 287(46): 38460-38472.
- Willemze, A.; Toes, R.E.M.; Huizinga, T.W.J. & Trouw, L.A. (2012), New biomarkers in rheumatoid arthritis.
- Curtis, J.R.; Mil, A.H.V. van; Knevel, R.; Huizinga, T.W.; Haney, D.J.; Shen, Y.J.; Ramanujan, S.; Cavet, G.; Centola, M.; Hesterberg, L.K.; Chernoff, D.; Ford, K.; Shadick, N.A.; Hamburger, M.; Fleischmann, R.; Keystone, E. & Weinblatt, M.E. (2012), Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity.
- Lange-Brokaar, B.J.E. de; Ioan-Facsinay, A.; Osch, G.J.V.M. van; Zuurmond, A.M.; Schoones, J.; Toes, R.E.M.; Huizinga, T.W.J. & Kloppenburg, M. (2012), Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review, Osteoarthritis and Cartilage 20(12): 1484-1499.
- Genovese, M.C.; Fleischmann, R.M.; Jasson, M.; Radin, A.R.; Hamilton, J. & Huizinga, T.W.J. (2012), Sarilumab, a Subcutaneously-Administered, Fully-Human Monoclonal Antibody Inhibitor of the IL-6 Receptor: Effects On Hemoglobin Levels in a Clinical Trial for the Treatment of Moderate-to-Severe Rheumatoid Arthritis, Arthritis and Rheumatism 64(10): S568-S568.
- Dirven, L.; Huizinga, T.W.J. & Allaart, C.F. (2012), Risk factors for reported influenza and influenza-like symptoms in patients with rheumatoid arthritis, Scandinavian Journal of Rheumatology 41(5): 359-365.
- Wevers-de Boer, K.V.C.; Heimans, L.; Visser, K.; Schouffoer, A.A.; Molenaar, T.H.E.; Harbers, J.B.; Bijkerk, C.; Speyer, I.; Buck, M. de; Sonnaville, P.B. de; Grillet, B.A.; Huizinga, T. & Allaart, C.F. (2012), Remission After One Year in ACPA Positive and ACPA Negative Patients with Early Arthritis, Arthritis and Rheumatism 64(10): S172-S172.
- Dirven, L.; Broek, M. van den; Groenendael, J.H.L.M. van; Beus, W.M. de; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Allaart, C.F. & Lems, W.F. (2012), Prevalence of vertebral fractures in a disease activity steered cohort of patients with early active rheumatoid arthritis, BMC Musculoskeletal Disorders 13: -.
- Heimans, L.; Wevers-de Boer, K.V.C.; Visser, K.; Goekoop, R.; Molenaar, T.H.E.; Grillet, B.A.; Huizinga, T. & Allaart, C.F. (2012), Patient Reported Outcomes in Early Arthritis Patients, Arthritis and Rheumatism 64(10): S1103-S1104.
- Rooy, D.P.C. de; Zhernakova, A.; Tsonaka, R.; Kurreeman, F.; Toes, R.E.M.; Huizinga, T.W.J.; Houwing-Duistermaat, J.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2012), New Genetic Risk Loci for the Radiographic Severity of Rheumatoid Arthritis, Arthritis and Rheumatism 64(10): S421-S422.
- Shi, J.; Janssen, G.; Veelen, P. van; Drijfhout, J.; Cerami, A.; Huizinga, T.; Trouw, L.A. & Toes, R.E.M. (2012), Recognition of Citrullinated and Carbamylated Proteins by Human Antibodies: Specificity, Cross-Reactivity and the "AMC-Senshu" Method., Arthritis and Rheumatism 64(10): S757-S757.
- Eyre, S.; Bowes, J.; Diogo, D.; Lee, A.; Barton, A.; Martin, P.; Zhernakova, A.; Stahl, E.; Viatte, S.; McAllister, K.; Amos, C.I.; Padyukov, L.; Toes, R.E.M.; Huizinga, T.W.J.; Wijmenga, C.; Trynka, G.; Franke, L.; Westra, H.J.; Alfredsson, L.; Hu, X.L.; Sandor, C.; Bakker, P.I.W. de; Davila, S.; Khor, C.C.; Heng, K.K.; Andrews, R.; Edkins, S.; Hunt, S.E.; Langford, C.; Symmons, D.; Concannon, P.; Onengut-Gumuscu, S.; Rich, S.S.; Deloukas, P.; Gonzalez-Gay, M.A.; Rodriguez-Rodriguez, L.; Arlsetig, L.; Martin, J.; Rantapaa-Dahlqvist, S.; Plenge, R.M.; Raychaudhuri, S.; Klareskog, L.; Gregersen, P.K.; Worthington, J.; Biol Rheumatoid Arthrit Genetics G & Wellcome Trust Case Control Consor (2012), High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis, Nature Genetics 44(12): 1336-1340.
- Broek, M. van den; Heimans, L.; Cessie, S. le; Siegerink, B.; Ronday, H.K.; Han, K.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2012), High Body Mass Index Is Associated with Decreased Response to Initial Combination Therapy in Recent Onset RA Patients., Arthritis and Rheumatism 64(10): S573-S573.
- Krabben, A.; Wilson, A.G.; Knevel, R.; Zhernakova, A.; Brouwer, E.; Lindqvist, E.; Saxne, T.; Stoeken-Rijsbergen, G.; Nies, J.A.B. van; Rooy, D.P.C. de; Huizinga, T.W.J.; Koeleman, B.P.C.; Toes, R.E.M.; Gregersen, P.K. & Helm-van Mil, A.H.M. van der (2012), Genetic Variants in the IL-4 and IL-4 Receptor Genes in Association with the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts, Arthritis and Rheumatism 64(10): S389-S389.
- Dirven, L.; Broek, M. van den; Peeters, A.J.; Riyazi, N.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Allaart, C.F. & Lems, W.F. (2012), Five Years of Treatment to Target in Early Active Rheumatoid Arthritis: Prevalence and Predictors of Vertebral Fractures, Arthritis and Rheumatism 64(10): S840-S840.
- Rooy, D.P.C. de; Andersson, M.L.E.; Knevel, R.; Huizinga, T.W.J.; Svensson, B. & Helm-van Mil, A.H.M. van der (2012), Does the season at symptom onset influence the long-term severity of radiographic joint destruction in rheumatoid arthritis?, Annals of the Rheumatic Diseases 71(12): 2055-U1.
- Buckley, F.; Finckh, A.; Huizinga, T.W.J.; Dejonckheere, F. & Jansen, J.P. (2012), Comparative Efficacy of Biologics As Monotherapy and in Combination with Methotrexate in Rheumatoid Arthritis Patients with an Inadequate Response to Conventional Dmards: A Network Meta-Analysis, Arthritis and Rheumatism 64(10): S918-S919.
- Heimans, L.; Wevers-de Boer, K.V.C.; Visser, K.; Ronday, H.K.; Oosterhout, M. van; Groenendael, J.H.L.M. van; Peeters, A.J.; Steup-Beekman, G.; Collee, G.; Sonnaville, P.B.J.; Grillet, B.A.; Huizinga, T. & Allaart, C.F. (2012), Clinical and Radiological Outcomes After One Year of Remission Steered Combination Treatment in Patients with Early Rheumatoid and Undifferentiated Arthritis., Arthritis and Rheumatism 64(10): S680-S680.
- Kerkman, P.; Voort, E.I.H. van der; Trouw, L.A.; Huizinga, T.W.J.; Toes, R.E.M. & Scherer, H.U. (2012), Circulating Plasmablasts As a Source of Anti-Citrullinated Protein Antibodies in Patients with Rheumatoid Arthritis, Arthritis and Rheumatism 64(10): S756-S756.
- Gvozdenovic, E.; Koevoets, R.; Wolterbeek, R.; Heijde, D. van der; Huizinga, T.W.J.; Allaart, C.F. & Landewe, R.B.M. (2012), Assessment of Global Disease Activity in Rheumatoid Arthritis Patients Monitored in the Measurement of Efficacy of Treatment in the Era of Rheumatology Database: The patient's Versus the rheumatologist's Opinion, Arthritis and Rheumatism 64(10): S173-S174.
- Shi, J.; Stadt, L.V. de; Levarht, N.; Huizinga, T.W.J.; Toes, R.E.M.; Trouw, L.A. & Schaardenburg, D. van (2012), Anti Carbamylated Protein Antibodies (Anti-CarP) Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis., Arthritis and Rheumatism 64(10): S757-S757.
- Hooge, M. de; Berg, R. van den; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), Almost 40% of Patients with Chronic Back Pain Starting Before the Age of 45 Fulfill the ASAS Axial Spondyloarthritis Criteria., Arthritis and Rheumatism 64(10): S245-S246.
- Liu, R.; Beaart-van de Voorde, L.J.J.; Huizinga, T.W.J. & Kloppenburg, M. (2012), Aesthetic Dissatisfaction in Hand Osteoarthritis Patients, Its Impact and Risk Factors, Arthritis and Rheumatism 64(10): S487-S488.
- Berg, R. van den; Hooge, M. de; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), Patients Fulfilling the Imaging-Arm and Patients Fulfilling the HLA-B27+Arm of the Assessment of Spondyloarthritis International Society Axial Spondyloarthritis Classification Criteria: Are They Similar?, Arthritis and Rheumatism 64(10): S933-S933.
- Hooge, M. de; Berg, R. van den; Reijnierse, M.; Navarro-Compan, V.; Gaalen, F. van; Huizinga, T. & Heijde, D. van der (2012), Localisation of Bone Marrow Edema in Sacroiliac Joints in Spondyloarthritis Patients: Does the Site of Lesions Change Over a 3-Month Period?, Arthritis and Rheumatism 64(10): S1106-S1107.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), Is It Useful to Repeat an MRI of the Sacroiliac Joints in the Diagnostic Work-up for Spondyloarthritis?, Arthritis and Rheumatism 64(10): S935-S935.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), How Useful Is Imaging of the Sacroiliac Joints (MRI and/or X-ray) in Patients with Possible Spondyloarthritis in the Diagnostic Work-up?, Arthritis and Rheumatism 64(10): S933-S933.
- Berg, R. van den; Hooge, M. de; Navarro-Compan, V.; Gaalen, F. van; Reijnierse, M.; Huizinga, T. & Heijde, D. van der (2012), How Much Does the Spondyloarthritis Research Consortium of Canada Score of the Sacroiliac Joints Change Over a 3-Month Period in Patients On Non-Biological Treatment?, Arthritis and Rheumatism 64(10): S935-S936.
- Krabben, A.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2012), Undifferentiated arthritis characteristics and outcomes when applying the 2010 and 1987 criteria for rheumatoid arthritis, Annals of the Rheumatic Diseases 71(2): 238-241.
- Knevel, R.; Grondal, G.; Huizinga, T.W.J.; Visser, A.W.; Jonsson, H.; Vikingsson, A.; Geirsson, A.J.; Steinsson, K. & Helm-van Mil, A.H.M. van der (2012), GENETIC PREDISPOSITION OF THE SEVERITY OF JOINT DESTRUCTION IN RHEUMATOID ARTHRITIS; A POPULATION BASED STUDY, Annals of the Rheumatic Diseases 71: -.
- Knevel, R.; Rooy, D.P. de; Gregersen, P.K.; Lindqvist, E.; Wilson, A.G.; Grondal, G.; Zhernakova, A.; Nies, J.A. van; Toes, R.E.; Tsonaka, R.; Houwing-Duistermaat, J.J.; Steinsson, K.; Huizinga, T.W.; Saxne, T. & Helm-van Mil, A.H. van der (2012), Studying associations between variants in TRAF1-C5 and TNFAIP3-OLIG3 and the progression of joint destruction in rheumatoid arthritis in multiple cohorts, Annals of the Rheumatic Diseases 71(10): 1753-U226.
- Wavers-de Boer, K.; Visser, K.; Heimans, L.; Ronday, H.K.; Molenaar, E.; Groenendael, J.H.L.M.; Peeters, A.J.; Westedt, M.L.; Collee, G.; Sonnaville, P.B.J. de; Grillet, B.A.M.; Huizinga, T.W.J. & Allaart, C.F. (2012), Remission induction therapy with methotrexate and prednisone in patients with early rheumatoid and undifferentiated arthritis (the IMPROVED study), Annals of the Rheumatic Diseases 71(9): 1472-1477.
- Broek, M. van den; Dirven, L.; Vries-Bouwstra, J.K. de; Dehpoor, A.J.; Goekoop-Ruiterman, Y.P.M.; Gerards, A.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2012), Rapid radiological progression in the first year of early rheumatoid arthritis is predictive of disability and joint damage progression during 8 years of follow-up, Annals of the Rheumatic Diseases 71(9): 1530-1533.
- Berg, R. van den; Gaalen, F. van; Helm-van Mil, A. van der; Huizinga, T. & Heijde, D. van der (2012), Performance of classification criteria for peripheral spondyloarthritis and psoriatic arthritis in the Leiden early arthritis cohort, Annals of the Rheumatic Diseases 71(8): 1366-1369.
- Luczak, A.; Knevel, R.; Huizinga, T.W.J.; Nies, J.A.B. van; Helm-van Mil, A. van der & Vries-Bouwstra, J.K. de (2012), No impact of serum uric acid on the outcome of recent-onset arthritis, Annals of the Rheumatic Diseases 71(8): 1424-1425.
- Knevel, R.; Krabben, A.; Brouwer, E.; Posthumus, M.D.; Wilson, A.G.; Lindqvist, E.; Saxne, T.; Rooy, D. de; Daha, N.; Linden, M.P.M. van der; Stoeken, G.; Toorn, L. van; Koeleman, B.; Tsonaka, R.; Zhernakoza, A.; Houwing-Duistermaat, J.J.; Toes, R.; Huizinga, T.W.J. & Helm-van Mil, A. van der (2012), Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: a multicohort study, Annals of the Rheumatic Diseases 71(10): 1651-1657.
- Gaalen, F. van; Verduijn, W.; Roelen, D.; Bohringer, S.; Huizinga, T.; Heijde, D. van der & Toes, R. (2012), EPISTASIS BETWEEN TWO HLA ANTIGENS DEFINES A SUBSET OF INDIVIDUALS AT A VERY HIGH RISK FOR ANKYLOSING SPONDYLITIS, Clinical and Experimental Rheumatology 30(4): 625-625.
- Stoop, J.N.; Shi, J.; Jansen, D.T.S.L.; Huizinga, T.W.; Trouw, L.A. & Toes, R.E. (2012), Anti-carbamylated protein antibodies are present in mice with collagen induced arthritis, Immunology 137: 572-572.
- Suurmond, J.; Bakker, A.M.; Knol, E.F.; Huizinga, T.W.J.; Toes, R.E.M. & Schuerwegh, A.J.M. (2012), TOLL-LIKE RECEPTOR TRIGGERING CAN SYNERGISE WITH IGE-MEDIATED ACTIVATION IN ACPA plus RA, Annals of the Rheumatic Diseases 71: -.
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- Rooy, D.P.C. de; Willemze, A.; Mertens, B.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Can Anti-Cyclic Citrullinated Peptide Antibody Negative Rheumatoid Arthritis Be Subdivided in Clinical Subphenotypes?, Arthritis and Rheumatism 63(10): S135-S135.
- Wyk, L. van; Marel, J. van der; Schuerwegh, A.J.M.; Schouffoer, A.A.; Voskuyl, A.E.; Huizinga, T.W.J.; Bianchi, D.W. & Scherjon, S.A. (2011), Increased incidence of pregnancy complications in women who later develop scleroderma: a case control study., Arthritis Research and Therapy 13(6): R183.
- Zirkzee, E.; Steup-Beekman, G.; Middelkoop, H.; Bollen, E.; Wee, N. van der; Baptist, E.; Mast, R. van der; Huisman, M.; Luyendijk, J.; Buchem, M. van & Huizinga, T. (2011), The Leiden Neuropsychiatric Systemic Lupus Erythematosus Clinic; Establishing Clinical Phenotypes, Arthritis and Rheumatism 63(10): S556-S556.
- Zirkzee, E.J.M.; Steup-Beekman, G.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2011), Health care usage in Dutch systemic lupus erythematosus (SLE) patients., Lupus.
- Bijsterbosch, J.; Haugen, I.K.; Malines, C.; Maheu, E.; Rosendaal, F.R.; Watt, I.; Berenbaum, F.; Kvien, T.K.; Heijde, D.M. van der; Huizinga, T.W.J. & Kloppenburg, M. (2011), Reliability, sensitivity to change and feasibility of three radiographic scoring methods for hand osteoarthritis, Annals of the Rheumatic Diseases 70(8): 1465-1467.
- Berg, R. van den; Reijnierse, M.; Huizinga, T.W.J. & Heijde, D.M.F.M. van der (2011), Proposal for An Adaptation of the Berlin Algorithm for Diagnosing Spa: Results of the SPondyloArthritis Caught Early (SPACE)-Cohort, Arthritis and Rheumatism 63(10): S506-S507.
- Kortekaas, M.C.; Kwok, W.Y.; Reijnierse, M.; Huizinga, T.W.J. & Kloppenburg, M. (2011), More Inflammatory Signs on Ultrasound in Interphalangeal Joints in Erosive Hand Osteoarthritis., Arthritis and Rheumatism 63(10): S417-S417.
- Berg, R. van den; Reijnierse, M.; Huizinga, T.W.J. & Heijde, D.M.F.M. van der (2011), Difference in Clinical Presentation of Patients with Spondyloarthritis with a Positive MRI of the SI Joints and/or HLA-B27 Positivity, Arthritis and Rheumatism 63(10): S198-S198.
- Dervieux, T.; Wessels, J.; Kremer, J.M.; Huizinga, T.W.J. & Guchelaar, H.J. (2011), Gene-Gene Interactions in Folate Pathway Contribute to Methotrexate Adverse Events in Rheumatoid Arthritis, Arthritis and Rheumatism 63(10): S331-S331.
- Dervieux T, Wessels J, Kremer JM, Padyukov L, Seddighzadeh M, Saevarsdottir S, van Vollenhoven RF, Klareskog L, Huizinga T & Guchelaar HJ (2011), Patterns of Interaction Between Genetic and Non-Genetic Attributes and Methotrexate Efficacy in Rheumatoid Arthritis, Arthritis and Rheumatism 63(10): S331-S332.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Kroon, H.M.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Association between Several Clinical and Radiological Determinants with Long-Term Clinical Progression and Good Prognosis of Lower Limb Osteoarthritis, PLoS ONE 6(10): -.
- Suwannalai, P.; Willemze, A.; Toorn, L. van; Stoeken-Rijsbergen, G.; Levarht, N.; Drijfhout, J.W.; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA, Arthritis Research and Therapy 13(6).
- Daha, N.A.; Kurreeman, F.A.S.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W.; Toes, R.E.M. & Trouw, L.A. (2011), Genetic variants of C1q are a risk for rheumatoid arthritis, Molecular Immunology 48(14): 1667-1667.
- Wheater, G.; Hogan, V.E.; Teng, Y.K.O.; Tekstra, J.; Lafeber, F.P.; Huizinga, T.W.J.; Bijlsma, J.W.J.; Francis, R.M.; Tuck, S.P.; Datta, H.K. & Laar, J.M. van (2011), Suppression of bone turnover by B-cell depletion in patients with rheumatoid arthritis.
- Genovese, M.C.; Kivitz, A.J.; Campos, J.A.S.; Rell-Bakalarska, M.; Fleischmann, R.M.; Jasson, M.; Radin, A.R.; Huang, X.H. & Huizinga, T.W.J. (2011), Sarilumab for the Treatment of Moderate-to-Severe Rheumatoid Arthritis: Results of a Phase 2, Randomized, Double-Blind, Placebo-Controlled, International Study, Arthritis and Rheumatism 63(12): 4041-4042.
- Wevers-de Boer, K.V.C.; Heimans, L.; Visser, K.; Ronday, H.K.; Molenaar, T.H.E.; Seys, P.E.H.; Bijkerk, C.; Westedt, M.L.; Beus, W. de; Sonnaville, P.B. de; Huizinga, T. & Allaart, C.F. (2011), Remission Induction Therapy with Methotrexate and Prednisone in Patients with Early Rheumatoid and Undifferentiated Arthritis., Arthritis and Rheumatism 63(10): S167-S168.
- Plenge, R.M.; Bridges, S.L.; Huizinga, T.W.J.; Criswell, L.A. & Gregersen, P.K. (2011), Recommendations for Publication of Genetic Association Studies in Arthritis & Rheumatism, Arthritis and Rheumatism 63(10): 2839-2847.
- Huizinga, T.W.J.; Emery, P.; Westhovens, R.; Bars, M. le; Gaillez, C.; Poncet, C.; Elegbe, A. & Smolen, J.S. (2011), Rate of Anti-Cyclic Citrullinated Peptide Antibody and Rheumatoid Factor Seroconversion in Patients with Undifferentiated Arthritis or Early Rheumatoid Arthritis Treated with Abatacept., Arthritis and Rheumatism 63(10): S872-S873.
- Broek, M. van den; Dirven, L.; Dehpoor, A.J.; Vries-Bouwstra, J.K. de; Goekoop-Ruiterman, Y.P.; Peeters, A.J.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2011), Rapid Radiological Progression in the First Year of Rheumatoid Arthritis Predicts Both Disability and Radiological Joint Damage Progression Over 8 Years of Targeted Treatment., Arthritis and Rheumatism 63(10): S157-S158.
- Knevel, R.; Krabben, A.; Brouwer, E.; Posthumus, M.D.; Saxne, T.; Lindqvist, E.; Wilson, A.G.; Rooy, D.P.C. de; Daha, N.; Linden, M.P.M. van der; Toes, R.E.M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Polymorfisms In IL15 Associate with Progression of Joint Destruction In Rheumatoid Arthritis; A Multi Cohort Study, Arthritis and Rheumatism 63(10): S132-S132.
- Knevel, R.; Grondal, G.; Huizinga, T.W.J.; Visser, A.W.; Jonsson, H.; Vikingsson, A.; Geirsson, A.J.; Steinsson, K. & Helm-van Mil, A.H.M. van der (2011), Genetic Predisposition of the Severity of Joint Destruction in Rheumatoid Arthritis; A Population Based Study, Arthritis and Rheumatism 63(10): S831-S831.
- Helm-van Mil, A.H.M. van der; Knevel, R.; Qureshi, F.; Manning, W.C.; Cavet, G.; Huizinga, T.W.J. & Haney, D.J. (2011), Evaluation of Definitions of Rheumatoid Arthritis Remission by Assessing Radiographic Progression in the Leiden Early Arthritis Cohort., Arthritis and Rheumatism 63(10): S121-S121.
- Dirven, L.; Broek, M. van den; Klarenbeek, N.B.; Han, K.H.; Ronday, H.K.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2011), Eight Year Results of Disease Activity Steered Treatment in a Large Recent Rheumatoid Arthritis Cohort: Clinical and Radiological Outcomes, Arthritis and Rheumatism 63(10): S858-S858.
- Weinblatt, M.; Fleischmann, R.M.; Vollenhoven, R.F. van; Emery, P.; Huizinga, T.W.J.; Cutolo, M.; Goldermann, R.; Duncan, B.; Davies, O. & Dougados, M. (2011), Efficacy and Safety of Certolizumab Pegol in a Broad Population of Patients with Active Rheumatoid Arthritis: Week 28 Results From a Phase IIIb Randomized Controlled Study, Arthritis and Rheumatism 63(10): S490-S491.
- Dougados, M.; Kissel, K.; Amital, H.; Conaghan, P.G.; Martin-Mola, E.; Nasonov, E.L.; Schett, G.; Troum, O.M.; Veldi, T.; Bernasconi, C. & Huizinga, T.W.J. (2011), Double-Blind Study of Tocilizumab Plus Methotrexate Vs Tocilizumab Plus Placebo in Patients with Active Rheumatoid Arthritis Despite Prior Methotrexate: Progression of Structural Damage, Quality of Life, and Physical Function At 24 Weeks., Arthritis and Rheumatism 63(10): S1032-S1033.
- Helm-van Mil, A.H.M. van der; Knevel, R.; Manning, W.C.; Hesterberg, L.K.; Cavet, G.; Huizinga, T.W.J. & Shen, Y.J. (2011), Development of a Multi-Biomarker Structural Damage Score in Rheumatoid Arthritis to Predict Radiographic Progression in the Leiden Early Arthritis Cohort, Arthritis and Rheumatism 63(10): S330-S330.
- Knevel, R.; Heijde, D. van der; Huizinga, T.W.J.; Lukas, C.; Combe, B.G. & Helm-Van Mil, A.H.M. van der (2011), Defining Erosive DISEASE Typical of RA In the LIGHT of the 2010 ACR/EULAR Criteria for Rheumatoid Arthritis-PHASE, Arthritis and Rheumatism 63(10): S957-S958.
- Heimans, L.; Broek, M. van den; Dirven, L.; Schouffoer, A.A.; Speyer, I.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2011), Body Mass Index Is Associated with Decreased Response to Initial and Delayed Treatment with Dose Escalated Infliximab in Patients with Recent Onset Rheumatoid Arthritis., Arthritis and Rheumatism 63(10): S156-S157.
- Hirata, S.; Dirven, L.; Cavet, G.; Shen, Y.J.; Centola, M.; Lems, W.F.; Huizinga, T.W.J.; Allaart, C.F. & Tanaka, Y. (2011), A Novel Multi-Biomarker Disease Activity Score (Vectra (TM) DA algorithm score) Reflects Clinical Disease Activity Score and Health Assessment Questionnaire for Rheumatoid Arthritis in the BeSt Study, Arthritis and Rheumatism 63(10): S132-S132.
- Dirven, L.; Guler-Yuksel, M.; Beus, W.M. de; Ronday, H.K.; Speyer, I.; Huizinga, T.W.J.; Dijkmans, B.A.C.; Allaart, C.F. & Lems, W.F. (2011), Changes in hand bone mineral density and the association with the level of disease activity in patients with rheumatoid arthritis: Bone mineral density measurements in a multicenter randomized clinical trial.
- Broek, M. van den; Dirven, L.; Kroon, H.M.; Oosterhout, M. van; Han, K.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Lems, W.F. & Allaart, C.F. (2011), Local Swelling and Prolonged Local Pain in a Large Joint Are Independent Predictors of Damage in That Joint in Recent Onset Rheumatoid Arthritis Patients, Arthritis and Rheumatism 63(10): S133-S133.
- Suwannalai, P.; Stadt, L.A. van de; Radner, H.; Steiner, G.; El-Gabalawy, H.S.; Jol-van der Zijde, C.M.; Tol, M.J. van; Schaardenburg, D. van; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), Avidity maturation of ACPA in rheumatoid arthritis., Arthritis and Rheumatism.
- Linden, M.P.M. van der; Batstra, M.R.; Bakker-Jonges, L.E.; Detert, J.; Bastian, H.; Scherer, H.U.; Toes, R.E.M.; Burmester, G.R.; Mjaavatten, M.D.; Kvien, T.K.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der & Fdn Quality Med Lab (2011), Toward a data-driven evaluation of the 2010 American College of Rheumatology/European League Against Rheumatism criteria for rheumatoid arthritis: is it sensible to look at levels of rheumatoid factor?, Arthritis and Rheumatism 63(5): 1190-9.
- Trouw, L.A.; Bohringer, S.; Daha, N.A.; Stahl, E.A.; Raychaudhuri, S.; Kurreeman, F.A.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W. & Toes, R.E. (2011), The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)., Clinical and Experimental Immunology 166(3): 333-7.
- Broek, M. van den; Dirven, L.; Klarenbeek, N.B.; Molenaar, T.H.E.; Han, K.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2011), The association of treatment response and joint damage with ACPA-status in recent-onset RA: a subanalysis of the 8-year follow-up of the BeSt study., Annals of the Rheumatic Diseases.
- Helm-van Mil, A.H.M. van der; Huizinga, T.W.J. & Cessie, S. le (2011), The additive value of MRI bone edema in predicting rheumatoid arthritis development in early undifferentiated arthritis. Comment on the manuscript of Duer-Jensen et al., Arthritis and Rheumatism.
- Willemze, A.; Bohringer, S.; Knevel, R.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Helm-van Mil, A.H.M. van der; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), The ACPA recognition profile and subgrouping of ACPA-positive RA patients., Annals of the Rheumatic Diseases.
- Vries-Bouwstra, J.K. de; Huizinga, T.W.J.; Willems, L.N. & Helm-van Mil, A.H.M. van der (2011), Diagnostic value of performing chest x-rays in patients presenting with recent-onset arthritis., Annals of the Rheumatic Diseases.
- Willemze, A.; Linden, M.P.M. van der; Cessie, S. le; Trouw, L.A.; Toes, R.E.M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics, Annals of the Rheumatic Diseases 70(9): 1697U401.
- Willemze, A.; Woude, D. van der; Ghidey, W.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Verduyn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2011), The Interaction Between HLA Shared Epitope Alleles and Smoking and Its Contribution to Autoimmunity Against Several Citrullinated Antigens, Arthritis and Rheumatism 63(7): 1823-1832.
- Klarenbeek, N.B.; Guler-Yuksel, M.; Kooij, S.M. van der; Han, K.H.; Ronday, H.K.; Kerstens, P.J.S.M.; Seys, P.E.H.; Huizinga, T.W.J.; Dijkmans, B.C. & Allaart, C.F. (2011), The impact of four dynamic, goal-steered treatment strategies on the 5-year outcomes of rheumatoid arthritis patients in the BeSt study, Annals of the Rheumatic Diseases 70(6): 1039-1046.
- Mosca, M.; Govoni, M.; Tomietto, P.; Aringer, M.; Boumpas, D.; Cervera, R.; Conti, F.; D'Cruz, D.; Doria, A.; Fuente, D. de la; Galeazzi, M.; Houssiau, F.; Huizinga, T.W.J.; Khamashta, M.A.; Ines, L.; Duarte, C.; Couto, M.; Meroni, P.; Montecucco, C.; Norkuviene, E.; Riemekasten, G.; Rios, V.; Schneider, M.; Shoenfeld, Y.; Steup-Beekman, G.M.; Szmyrka-Kaczmarek, M.; Tani, C.; Tincani, A.; Tzioufas, A.G.; Voll, R.; Bencivelli, W.; Salaffi, F. & Bombardieri, S. (2011), The development of a simple questionnaire to screen patients with SLE for the presence of neuropsychiatric symptoms in routine clinical practice, Lupus 20(5): 485-492.
- Schouffoer, A.A.; Ninaber, M.K.; Beaart-van de Voorde, L.J.J.; Giesen, F.J. van der; Jong, Z. de; Stolk, J.; Voskuyl, A.E.; Scherptong, R.W.C.; Laar, J.M. van; Schuerwegh, A.J.M.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2011), Randomized Comparison of a Multidisciplinary Team Care Program With Usual Care in Patients With Systemic Sclerosis, ARTHRITIS CARE & RESEARCH 63(6): 909-917.
- Meeuwisse, C.M.; Linden, M.P. van der; Rullmann, T.A.; Allaart, C.F.; Nelissen, R.; Huizinga, T.W.; Garritsen, A.; Toes, R.E.; Schaik, R. van & Helm-van Mil, A.H. van der (2011), Identification of CXCL13 as a Marker for Rheumatoid Arthritis Outcome Using an In Silico Model of the Rheumatic Joint, Arthritis and Rheumatism 63(5): 1265-1273.
- Bax, M.; Heemst, J. van; Huizinga, T.W.J. & Toes, R.E.M. (2011), Genetics of rheumatoid arthritis: what have we learned?, Immunogenetics 63(8): 459-466.
- Scherer, H.U.; Woude, D. van der; Willemze, A.; Trouw, L.A.; Knevel, R.; Syversen, S.W.; Linden, M.P.M. van der; Lie, B.; Huizinga, T.W.J.; Heijde, D.M.F.M. van der; Helm-van Mil, A.H.M. van der; Kvien, T.K. & Toes, R.E.M. (2011), Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis, Annals of the Rheumatic Diseases 70(8): 1461-1464.
- Broek, M. van den; Klarenbeek, N.B.; Dirven, L.; Schaardenburg, D. van; Hulsmans, H.M.J.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2011), Discontinuation of infliximab and potential predictors of persistent low disease activity in patients with early rheumatoid arthritis and disease activity score-steered therapy: subanalysis of the BeSt study, Annals of the Rheumatic Diseases 70(8): 1389-1394.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis, Osteoarthritis and Cartilage 19(9): 1117-1122.
- Allaart, C.F. & Huizinga, T.W.J. (2011), Treatment strategies in recent onset rheumatoid arthritis, Current Opinion in Rheumatology 23(3): 241-244.
- Shi, J.; Bohringer, S.; Stahl, E.A.; Raychaudhuri, S.; Kurreeman, F.A.; Houwing-Duistermaat, J.J.; Huizinga, T.W.; Toes, R.E. & Trouw, L.A. (2011), THE MAJOR RISK ALLELES OF AGE RELATED MACULAR DEGENERATION IN CFH, DO NOT PLAY A MAJOR ROLE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70.
- Wheater, G.; Hogan, V.E.; Teng, Y.K.O.; Tekstra, J.; Tuck, S.P.; Lafeber, F.P.; Huizinga, T.W.; Bijlsma, J.W.; Francis, R.M.; Datta, H.K. & Laar, J. van (2011), SUPPRESSION OF BONE TURNOVER BY B-CELL DEPLETION IN PATIENTS WITH RHEUMATOID ARTHRITIS, Rheumatology 50: 101-101.
- Kochi, Y.; Thabet, M.M.; Suzuki, A.; Okada, Y.; Daha, N.A.; Toes, R.E.M.; Huizinga, T.W.J.; Myouzen, K.; Kubo, M.; Yamada, R.; Nakamura, Y. & Yamamoto, K. (2011), PADI4 polymorphism predisposes male smokers to rheumatoid arthritis, Annals of the Rheumatic Diseases 70(3): 512-515.
- Luyendijk, J.; Steens, S.C.A.; Ouwendijk, W.J.N.; Steup-Beekman, G.M.; Bollen, E.L.E.M.; Grond, J. van der; Huizinga, T.W.J.; Emmer, B.J. & Buchem, M.A. van (2011), Neuropsychiatric Systemic Lupus Erythematosus Lessons Learned From Magnetic Resonance Imaging, Arthritis and Rheumatism 63(3): 722-732.
- Zhernakova, A.; Stahl, E.A.; Trynka, G.; Raychaudhuri, S.; Festen, E.; Franke, L.; Fehrmann, R.S.N.; Kurreeman, F.A.S.; Thomson, B.; Gupta, N.; Romanos, J.; McManus, R.; Ryan, A.W.; Turner, G.; Remmers, E.F.; Greco, L.; Toes, R.; Grandone, E.; Mazzilli, M.C.; Rybak, A.; Cukrowska, B.; Li, Y.H.; Bakker, P.I.W. de; Gregersen, P.K.; Worthington, J.; Siminovitch, K.A.; Klareskog, L.; Huizinga, T.W.J.; Wijmenga, C. & Plenge, R.M. (2011), META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IN CELIAC DISEASE AND RHEUMATOID ARTHRITIS IDENTIFIES FOURTEEN NON-HLA SHARED LOCI, Annals of the Rheumatic Diseases 70: A21A21.
- Zhernakova, A.; Stahl, E.A.; Trynka, G.; Raychaudhuri, S.; Festen, E.A.; Franke, L.; Westra, H.J.; Fehrmann, R.S.N.; Kurreeman, F.A.S.; Thomson, B.; Gupta, N.; Romanos, J.; McManus, R.; Ryan, A.W.; Turner, G.; Brouwer, E.; Posthumus, M.D.; Remmers, E.F.; Tucci, F.; Toes, R.; Grandone, E.; Mazzilli, M.C.; Rybak, A.; Cukrowska, B.; Coenen, M.J.H.; Radstake, T.R.D.J.; Riel, P.L.C.M. van; Li, Y.H.; Bakker, P.I.W. de; Gregersen, P.K.; Worthington, J.; Siminovitch, K.A.; Klareskog, L.; Huizinga, T.W.J.; Wijmenga, C. & Plenge, R.M. (2011), Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci, PLoS Genetics 7(2).
- Suurmond, J.; Dorjee, A.L.; Boon, M.R.; Knol, E.F.; Huizinga, T.W.J.; Toes, R.E.M. & Schuerwegh, A.J.M. (2011), MAST CELLS ARE THE MAIN IL-17 PRODUCING CELLS IN SYNOVIUM OF ANTI-CITRULLINATED PROTEIN ANTIBODY-POSITIVE AND -NEGATIVE RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS PATIENTS, Annals of the Rheumatic Diseases 70: A37A37.
- Huizinga, T. (2011), INFLAMMATORY ARTHRITIS: PROSPECTS FOR NEXT DECADE, Rheumatology 50: 11-11.
- Trouw, L.A.; Kurreeman, F.A.S.; Daha, N.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W. & Toes, R.E. (2011), GENETIC VARIANTS OF C1Q ARE A RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A17A17.
- Daha, N.A.; Willemze, A.; Robinson, D.B.; Oen, K.G.; Smolik, I.; Hart, D.; Ghidey, W.; Houwing-Duistermaat, J.J.; Siminovitch, K.A.; Huizinga, T.W.J.; El-Gabalawy, H.S. & Toes, R.E.M. (2011), GENETIC INTERACTION IN THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A84A84.
- Broek, M. van den; Huizinga, T.W.J.; Dijkmans, B.C. & Allaart, C.F. (2011), Drug-free remission: is it already possible?, Current Opinion in Rheumatology 23(3): 266-272.
- Scherer, H.U.; Woude, D. van der; Willemze, A.; Trouw, L.A.; Knevel, R.; Syversen, S.W.; Linden, M.P.M. van der; Lie, B.; Huizinga, T.W.J.; Heijde, D.M.F.M. van der; Helm-van Mil, A.H.M. van der; Kvien, T.K. & Toes, R.E.M. (2011), DISTINCT ACPA FINE-SPECIFICITIES, FORMED UNDER THE INFLUENCE OF HLA SHARED EPITOPE ALLELES, HAVE NO EFFECT ON RADIOGRAPHIC JOINT DAMAGE IN RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A5A5.
- Klein-Wieringa, I.R.; Linden, M.P.M. van der; Kwekkeboom, J.C.; Beelen, E. van; Helm-van Mil, A. van der; Kloppenburg, M.; Huizinga, T.W.J.; Toes, R.E.M. & Ioan-Facsinay, A. (2011), ADIPONECTIN IS A PREDICTOR FOR RADIOGRAPHIC PROGRESSION IN EARLY RA PATIENTS, INDEPENDENTLY OF ANTI-CCP ANTIBODIES, Annals of the Rheumatic Diseases 70.
- Bijsterbosch, J.; Bemmel, J.M. van; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Systemic and local factors are involved in the evolution of erosions in hand osteoarthritis, Annals of the Rheumatic Diseases 70(2): 326-330.
- Goekoop, R.J.; Kloppenburg, M.; Kroon, H.M.; Dirkse, L.E.V.; Huizinga, T.W.J.; Westendorp, R.G.J. & Gussekloo, J. (2011), Determinants of absence of osteoarthritis in old age, Scandinavian Journal of Rheumatology 40(1): 68-73.
- Luyendijk, J.; Steens, S.C.A.; Ouwendijk, W.J.N.; Steup-Beekman, G.M.; Bollen, E.L.E.M.; Grond, J. van der; Huizinga, T.W.J.; Emmer, B.J. & Buchem, M.A. van (2011), Neuropsychiatric systemic lupus erythematosus: Lessons learned from magnetic resonance imaging., Arthritis and Rheumatism 63(3): 722-32.
- Bijsterbosch, J.; Bemmel, J.M. van; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Systemic and local factors are involved in the evolution of erosions in hand osteoarthritis., Annals of the Rheumatic Diseases 70(2): 326-30.
- Rooy, D.P.C. de; Linden, M.P.M. van der; Knevel, R.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?, Rheumatology 50(1): 93-100.
- Yusuf, E.; Kortekaas, M.C.; Watt, I.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review., Annals of the Rheumatic Diseases 70(1): 60-7.
- Linden, M.P.M. van der; Knevel, R.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Classification of rheumatoid arthritis: comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European League Against Rheumatism criteria., Arthritis and Rheumatism 63(1): 37-42.
- Schouffoer, A.A.; Ninaber, M.K.; Beaart-van de Voorde, L.J.J.; Giesen, F.J. van der; Jong, Z. de; Stolk, J.; Voskuyl, A.E.; Scherptong, R.W.C.; Laar, J.M. van; Schuerwegh, A.J.M.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2011), A randomised comparison of a multidisciplinary team care program with usual care in patients with systemic sclerosis., Arthritis Care and Research.
- Suwannalai, P.; Scherer, H.U.; Woude, D. van der; Ioan-Facsinay, A.; Jol-van der Zijde, C.M.; Tol, M.J.D. van; Drijfhout, J.W.; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens., Annals of the Rheumatic Diseases 70(2): 373-9.
- Wang, J.; Bax, M.; Balog, C.I.A.; Stavenhagen, K.; Koeleman, C.A.M.; Scherer, H.U.; Deelder, A.M.; Huizinga, T.W.J.; Toes, R.E.M. & Wuhrer, M. (2011), FC-GLYCOSYLATION OF IGG1 IS MODULATED BY B CELL STIMULI, Annals of the Rheumatic Diseases 70.
- Rooy, D.P.C. de; Linden, M.P.M. van der; Knevel, R.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Predicting arthritis outcomes-what can be learned from the Leiden Early Arthritis Clinic?, Rheumatology 50(1): 93-100.
- Heron, M.; Moorsel, C.H.M. van; Grutters, J.C.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der; Nagtegaal, M.M.; Ruven, H.J.T. & Bosch, J.M.M. van den (2011), Genetic variation in GREM1 is a risk factor for fibrosis in pulmonary sarcoidosis, Tissue Antigens 77(2): 112-117.
- Linden, M.P.M. van der; Knevel, R.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Classification of Rheumatoid Arthritis Comparison of the 1987 American College of Rheumatology Criteria and the 2010 American College of Rheumatology/European League Against Rheumatism Criteria, Arthritis and Rheumatism 63(1): 37-42.
- Yusuf, E.; Kortekaas, M.C.; Watt, I.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review, Annals of the Rheumatic Diseases 70(1): 60-67.
- Bijsterbosch, J.; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2011), Clinical and radiographic disease course of hand osteoarthritis and determinants of outcome after 6 years, Annals of the Rheumatic Diseases 70(1): 68-73.
- Nitiham, J.; Taylor, K.E.; Aulchenko, Y.S.; Oostra, B.; Plenge, R.M.; Huizinga, T.W.J.; Gregersen, P.K.; Duijn, C.M. van & Criswell, L.A. (2011), Genome-Wide Association Study and Comparison of Risk Alleles for Rheumatoid Arthritis in An Isolated Dutch Population, Arthritis and Rheumatism 63(10): S842-S843.
- Allaart, C.F.; Dirven, L.; Hirata, S.; Kerstens, P.J.S.M.; Dijkmans, B.A.C.; Chernoff, D.; Cavet, G.; Centola, M.; Hesterberg, L.K.; Tanaka, Y.; Huizinga, T.W.J. & Shen, Y.J. (2011), A Multi-Biomarker Disease Activity (Vectra DA) Algorithm Score for Rheumatoid Arthritis Predicts Radiographic Progression in the BeSt Study, Arthritis and Rheumatism 63(10): S630-S630.
- Heimans, L.; Wevers-de Boer, K.V.C.; Visser, K.; Huizinga, T.W.J.; Ronday, H.K.; Westedt, M.L.; Molenaar, T.H.E.; Mast, R.C. van der & Allaart, C.F. (2011), Optimism and Depressive Scores in Early Arthritis Patients Before and After Treatment with Methotrexate and a Tapered High Dose of Prednisone in the IMPROVED Study, Arthritis and Rheumatism 63(10): S861-S861.
- Zirkzee, E.J.M.; Steup-Beekman, G.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Huizinga, T.W.J. & Vlieland, T.P.M.V. (2011), Health care usage in Dutch systemic lupus erythematosus patients, Lupus 20(11): 1147-1154.
- Rooy, D.P.C. de; Willemze, A.; Mertens, B.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2011), Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?, Arthritis Research and Therapy 13(5): R180.
- Dirven, L.; Visser, K.; Klarenbeek, N.B.; Ewals, J.A.P.M.; Han, K.H.; Peeters, A.J.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2011), Towards personalized treatment: predictors of short-term HAQ response in recent-onset active rheumatoid arthritis are different from predictors of rapid radiological progression., Scandinavian Journal of Rheumatology.
- Suwannalai, P.; Trouw, L.A.; Toes, R.E.M. & Huizinga, T.W.J. (2011), Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.
- Koevoets, R.; Klarenbeek, N.B.; Guler-Yuksel, M.; Oosterhout, M. van; Krugten, M.V. van; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C.; Heijde, D.M.F.M. van der & Allaart, C.F. (2011), Simplified versions of the original disease activity score: validation in the BeSt trial, Annals of the Rheumatic Diseases 70(8): 1471-1474.
- Suwannalai, P.; Scherer, H.U.; Ioan-Facsinay, A.; Jol-van der Zijde; Tol, M.J.D. van; Helm-van Mil, A.H. van der; Knevel, R.; Huizinga, T.W.J.; Toes, R.E.M. & Trouw, L.A. (2011), Low avidity anti-citrullinated protein antibodies (ACPA) are associated with high radiographic progression in Rheumatoid Arthritis, Annals of the Rheumatic Diseases 70: A60A60.
- Klarenbeek, N.B.; Guler-Yuksel, M.; Heijde, D.M.F.M. van der; Kerstens, P.J.S.M.; Mallee, C.; Westedt, M.L.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2011), A comparison between the simplified erosion and narrowing score and the Sharp-van der Heijde score: post hoc analysis from the BeSt study, Annals of the Rheumatic Diseases 70(4): 714U214.
- Ioan-Facsinay, A.; El-Bannoudi, H.; Scherer, H.U.; Woude, D. van der; Menard, H.A.; Lora, M.; Trouw, L.A.; Huizinga, T.W.J. & Toes, R.E.M. (2011), Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities, Annals of the Rheumatic Diseases 70(1): 188-193.
- Willemze, A.; Woude, D. van der; Alemayehu, W.G.; Levarht, E.W.N.; Stoeken-Rijsbergen, G.; Verduyn, W.; Vries, R.R.P. de; Houwing, J.; Huizinga, T.W.J.; Trouw, L.A. & Toes, R.E.M. (2011), THE INTERACTION BETWEEN HLA SE ALLELES AND SMOKING AND ITS CONTRIBUTION TO AUTOIMMUNITY AGAINST SEVERAL CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 70: A1A1.
- Wang J., Han W.G., Foks A.C., Huizinga T.W.J. & Toes R.E.M. (2010), Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains, Molecular Immunology 48(1-3): 137-146.
- Bijsterbosch, J.; Bemmel, J.M. van; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W. & Kloppenburg, M. (2010), CARTILAGE LOSS AND PAIN ARE INDEPENDENT RISK FACTORS IN THE EVOLUTION OF EROSIVE HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S126S126.
- Bijsterbosch, J.; Visser, W. & Kroon, H.M. (2010), Thumb base involvement in symptomatic hand osteoarthritis is associated with more pain and functional disability., Annals of the Rheumatic Diseases.
- Bijsterbosch, J.; Visser, W.; Kroon, H.M.; Stamm, T.; Meulenbelt, I.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Thumb base involvement in symptomatic hand osteoarthritis is associated with more pain and functional disability., Annals of the Rheumatic Diseases.
- Yusuf, E.; Bijsterbosch, J.; Slagboom, P.E.; Kroon, H.; Rosendaal, F.R.; Huizinga, T.W. & Kloppenburg, M. (2010), DETERMINANTS OF CLINICAL PROGRESSION OF LOWER EXTREMITY OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S159S159.
- Bijsterbosch, J.; Visser, W.; Kroon, H.M.; Stamm, T.; Meulenbelt, I.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Thumb base involvement in symptomatic hand osteoarthritis is associated with more pain and functional disability, Annals of the Rheumatic Diseases 69(3): 585-587.
- Emmer, B.J.; Osch, M.J. van; Wu, O.; Steup-Beekman, G.M.; Steens, S.C.; Huizinga, T.W.; Buchem, M.A. van & Grond, J. van der (2010), Perfusion MRI in Neuro-Psychiatric Systemic Lupus Erthemathosus, Journal of Magnetic Resonance Imaging 32(2): 283-288.
- Luyendijk, J.; Steens, S.C.A.; Ouwendijk, W.J.N.; Steup-Beekman, G.M.; Bollen, E.L.E.M.; Grond, J. van der; Huizinga, T.W.J.; Emmer, B.J. & Buchem, M.A. van (2010), Neuropsychiatric SLE: Lessons learned from MRI., Arthritis and Rheumatism.
- Woude, D. van der; Alemayehu, W.G.; Daha, N.A.; Verduyn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J. & Toes, R.E.M. (2010), A GENE - ENVIRONMENT INTERACTION BETWEEN HLA SE ALLELES AND SMOKING AFFECTS THE REACTIVITY OF ACPA TO VARIOUS CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 69.
- Woude, D. van der; Alemayehu, W.G.; Verduijn, W.; Vries, R.R.P. de; Houwing-Duistermaat, J.J.; Huizinga, T.W.J. & Toes, R.E.M. (2010), Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis, Nature Genetics 42(10): 814-816.
- Marques, R.B.; Thabet, M.M.; White, S.J.; Houwing-Duistermaat, J.J.; Bakker, A.M.; Hendriks, G.J.; Zhernakova, A.; Huizinga, T.W.; Helm-van Mil, A.H. van der & Toes, R.E. (2010), Genetic Variation of the Fc Gamma Receptor 3B Gene and Association with Rheumatoid Arthritis, PLoS ONE 5(10).
- Woude, D. van der; Lie, B.A.; Lundstrom, E.; Balsa, A.; Feitsma, A.L.; Houwing-Duistermaat, J.J.; Verduijn, W.; Nordang, G.B.N.; Alfredsson, L.; Klareskog, L.; Pascual-Salcedo, D.; Gonzalez-Gay, M.A.; Lopez-Nevot, M.A.; Valero, F.; Roep, B.O.; Huizinga, T.W.J.; Kvien, T.K.; Martin, J.; Padyukov, L.; Vries, R.R.P. de & Toes, R.E.M. (2010), Protection Against Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis Is Predominantly Associated With HLA-DRB1*1301 A Meta-Analysis of HLA-DRB1 Associations With Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis in Four European Populations, Arthritis and Rheumatism 62(5): 1236-1245.
- Nies, J.A.B. van; Knevel, R.; Daha, N.; Linden, M.P.M. van der; Gregersen, P.K.; Kern, M.; Cessie, S.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Toes, R.E.M. & Helm-van Mil, A.H.M. van der (2010), The PTPN22 susceptibility risk variant is not associated with the rate of joint destruction in anti-citrullinated protein antibody-positive rheumatoid arthritis, Annals of the Rheumatic Diseases 69(9): 1730U24.
- Kurreeman, F.A.S.; Goulielmos, G.N.; Alizadeh, B.Z.; Rueda, B.; Houwing-Duistermaat, J.; Sanchez, E.; Bevova, M.; Radstake, T.R.; Vonk, M.C.; Galanakis, E.; Ortego, N.; Verduyn, W.; Zervou, M.I.; Roep, B.O.; Dema, B.; Espino, L.; Urcelay, E.; Boumpas, D.T.; Berg, L.H. van den; Wijmenga, C.; Koeleman, B.P.C.; Huizinga, T.W.J.; Toes, R.E.M.; Martin, J.; AADEA Grp & SLEGEN Consortium (2010), The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases, Annals of the Rheumatic Diseases 69(4): 696-699.
- Bijsterbosch, J.; Watt, I.; Meulenbelt, I.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Clinical burden of erosive hand osteoarthritis and its relationship to nodes, Annals of the Rheumatic Diseases 69(10): 1784-1788.
- Guler-Yuksel, M.; Klarenbeek, N.B.; Goekoop-Ruiterman, Y.P.M.; Vries-Bouwstra, J.K. de; Kooij, S.M. van der; Gerards, A.H.; Ronday, H.K.; Huizinga, T.W.J.; Dijkmans, B.A.C.; Allaart, C.F. & Lems, W.F. (2010), Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis, Arthritis Research and Therapy 12(3).
- Goekoop-Ruiterman, Y.P.M. & Huizinga, T.W.J. (2010), RHEUMATOID ARTHRITIS Can we achieve true drug-free remission in patients with RA?, Nature Reviews Rheumatology 6(2): 68-70.
- Yusuf, E.; Ioan-Facsinay, A.; Bijsterbosch, J.; Kwekkeboom, J.C.; Slagboom, P.E.; Huizinga, T.W. & Kloppenburg, M. (2010), ASSOCIATION BETWEEN ADIPOKINES AND PROGRESSION OF HAND OSTEOARTHRITIS, Osteoarthritis and Cartilage 18: S58S59.
- Kortekaas, M.C.; Kwok, W.Y.; Reijnierse, M.; Watt, I.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Pain in hand osteoarthritis is associated with inflammation: the value of ultrasound, Annals of the Rheumatic Diseases 69(7): 1367-1369.
- Brakenhoff, L.K.P.M.; Heijde, D.M. van der; Hommes, D.W.; Huizinga, T.W.J. & Fidder, H.H. (2010), The joint-gut axis in inflammatory bowel diseases, Journal of Crohn's and Colitis 4(3): 257-268.
- Kooloos, W.M.; Huizinga, T.W.J.; Guchelaar, H.J. & Wessels, J.A.M. (2010), Pharmacogenetics in Treatment of Rheumatoid Arthritis, Current Pharmaceutical Design 16(2): 164-175.
- Wheater, G.; Hogan, V.E.; Teng, Y.K.O.; Tekstra, J.; Tuck, S.P.; Lafeber, F.P.; Huizinga, T.W.J.; Bijlsma, J.W.J.; Francis, R.M.; Datta, H.K. & Laar, J.M. van (2010), (PREMIER POSTER-AWARD CANDIDATE) SUPPRESSION OF BONE TURNOVER BY B-CELL DEPLETION IN PATIENTS WITH RHEUMATOID ARTHRITIS, Osteoporosis International 21: S463S463.
- Wang, J.; Han, W.G.H.; Foks, A.C.; Huizinga, T.W.J. & Toes, R.E.M. (2010), Neutralization of IL-4 reverses the nonresponsiveness of CD4(+) T cells to regulatory T-cell induction in non-responder mouse strains, Molecular Immunology 48(1-3): 137-146.
- Visser, K.; Allaart, C.F. & Huizinga, T.W.J. (2010), Use of methotrexate in undifferentiated arthritis., Clinical and Experimental Rheumatology 28(5 Suppl 61): S117-21.
- Guler-Yuksel, M.; Allaart, C.F.; Watt, I.; Goekoop-Ruiterman, Y.P.M.; Vries-Bouwstra, J.K. de; Schaardenburg, D. van; Krugten, M.V. van; Dijkmans, B.A.C.; Huizinga, T.W.J.; Lems, W.F. & Kloppenburg, M. (2010), Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis., Osteoarthritis and Cartilage 18(10): 1256-62.
- Linden, M.P.M. van der; Batstra, M.R.; Bakker-Jonges, L.E.; Detert, J.; Bastian, H.; Scherer, H.U.; Toes, R.E.M.; Burmester, G.R.; Mjaavatten, M.D.; Kvien, T.K.; Huizinga, T.W.J.; Helm-van Mil, A.H.M. van der & Fdn Quality Med Lab (2010), Towards a data-driven evaluation of the 2010 ACR/EULAR criteria for rheumatoid arthritis: Is it sensible to look at levels of rheumatoid factor?, Arthritis and Rheumatism.
- Brakenhoff, L.K.P.M.; Heijde, D.M. van der; Hommes, D.W.; Huizinga, T.W.J. & Fidder, H.H. (2010), The joint-gut axis in inflammatory bowel diseases.
- Wang, J.; Han, W.G.H.; Foks, A.C.; Huizinga, T.W.J. & Toes, R.E.M. (2010), Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains.
- Helm-van Mil, A.H.M. van der; Knevel, R.; Heijde, D. van der & Huizinga, T.W.J. (2010), How to avoid phenotypic misclassification in using joint destruction as an outcome measure for rheumatoid arthritis?, Rheumatology 49(8): 1429-35.
- Han, W.G.H.; Voort, E.I.H. van der; Bannoudi, H. el; Louis-Plence, P.; Huizinga, T.W.J. & Toes, R.E.M. (2010), DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4., European Journal of Immunology 40(10): 2731-40.
- Fransen, J.; Visser, K.; Dongen, H. van; Huizinga, T.; Riel, P.L.C.M. van & Heijde, D.M. van der (2010), Validity of the Disease Activity Score in Undifferentiated Arthritis, ARTHRITIS CARE & RESEARCH 62(10): 1392-1398.
- Machold, K.P.; Landewe, R.; Smolen, J.S.; Stamm, T.A.; Heijde, D.M. van der; Verpoort, K.N.; Brickmann, K.; Vazquez-Mellado, J.; Karateev, D.E.; Breedveld, F.C.; Emery, P. & Huizinga, T.W.J. (2010), The Stop Arthritis Very Early (SAVE) trial, an international multicentre, randomised, double-blind, placebo-controlled trial on glucocorticoids in very early arthritis, Annals of the Rheumatic Diseases 69(3): 495-502.
- Neogi, T.; Aletaha, D.; Silman, A.J.; Naden, R.L.; Felson, D.T.; Aggarwal, R.; Bingham, C.O.; Birnbaum, N.S.; Burmester, G.R.; Bykerk, V.P.; Cohen, M.D.; Combe, B.; Costenbader, K.H.; Dougados, M.; Emery, P.; Ferraccioli, G.; Hazes, J.M.W.; Hobbs, K.; Huizinga, T.W.J.; Kavanaugh, A.; Kay, J.; Khanna, D.; Kvien, T.K.; Laing, T.; Liao, K.; Mease, P.; Menard, H.A.; Moreland, L.W.; Nair, R.; Pincus, T.; Ringold, S.; Smolen, J.S.; Stanislawska-Biernat, E.; Symmons, D.; Tak, P.P.; Upchurch, K.S.; Vencovsky, J.; Wolfe, F. & Hawker, G. (2010), The 2010 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Rheumatoid Arthritis Phase 2 Methodological Report, Arthritis and Rheumatism 62(9): 2582-2591.
- Funovits, J.; Aletaha, D.; Bykerk, V.; Combe, B.; Dougados, M.; Emery, P.; Felson, D.; Hawker, G.; Hazes, J.M.; Huizinga, T.; Kay, J.; Kvien, T.K.; Smolen, J.S.; Symmons, D.; Tak, P.P. & Silman, A. (2010), The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Methodological Report Phase I, Annals of the Rheumatic Diseases 69(9): 1589-1595.
- Tuyl, L.H.D. van; Boers, M.; Lems, W.F.; Landewe, R.B.; Han, H.; Linden, S. van der; Laar, M. van de; Westhovens, R.; Denderen, J.C. van; Westedt, M.L.; Peeters, A.J.; Jacobs, P.; Huizinga, T.W.J.; Brink, H. van de; Dijkmans, B.A.C. & Voskuyl, A.E. (2010), Survival, comorbidities and joint damage 11 years after the COBRA combination therapy trial in early rheumatoid arthritis, Annals of the Rheumatic Diseases 69(5): 807-812.
- Scott, D.L.; Wolfe, F. & Huizinga, T.W.J. (2010), Rheumatoid arthritis, Lancet 376(9746): 1094-1108.
- Linden, M.P.M. van der; Boja, R.; Klarenbeek, N.B.; Huizinga, T.W.J.; Heijde, D.M. van der & Helm-van Mil, A.H.M. van der (2010), Repair of joint erosions in rheumatoid arthritis: prevalence and patient characteristics in a large inception cohort, Annals of the Rheumatic Diseases 69(4): 727-729.
- Martin-Trujillo, A.; Rietschoten, J.G.I. van; Timmer, T.C.G.; Rodriguez, F.M.; Huizinga, T.W.J.; Tak, P.P.; Marsal, S.; Ibrahim, S.M.; Dijkmans, B.A.C.; Kraan, T.C.T.M.V. & Verweij, C.L. (2010), Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis, Annals of the Rheumatic Diseases 69(6): 1239-1242.
- Lard, L.R. & Huizinga, T.W.J. (2010), Just Another Case of Sjogren's Syndrome?, Journal of Rheumatology 37(6): 1363-1364.
- Nies, J.A.B. van; Jong, Z. de; Helm-van Mil, A.H.M. van der; Knevel, R.; Cessie, S. le & Huizinga, T.W.J. (2010), Improved treatment strategies reduce the increased mortality risk in early RA patients, Rheumatology 49(11): 2210-2216.
- Helm-van Mil, A.H.M. van der; Knevel, R.; Heijde, D. van der & Huizinga, T.W.J. (2010), How to avoid phenotypic misclassification in using joint destruction as an outcome measure for rheumatoid arthritis?, Rheumatology 49(8): 1429-1435.
- Schoels, M.; Knevel, R.; Aletaha, D.; Bijlsma, J.W.J.; Breedveld, F.C.; Boumpas, D.T.; Burmester, G.; Combe, B.; Cutolo, M.; Dougados, M.; Emery, P.; Heijde, D. van der; Huizinga, T.W.J.; Kalden, J.; Keystone, E.C.; Kvien, T.K.; Martin-Mola, E.; Montecucco, C.; Wit, M. de & Smolen, J.S. (2010), Evidence for treating rheumatoid arthritis to target: results of a systematic literature search, Annals of the Rheumatic Diseases 69(4): 638-643.
- Knevel, R.; Schoels, M.; Huizinga, T.W.J.; Aletaha, D.; Burmester, G.R.; Combe, B.; Landewe, R.B.; Smolen, J.S.; Sokka, T. & Heijde, D.M.F.M. van der (2010), Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis, Annals of the Rheumatic Diseases 69(6): 987-994.
- Aletaha, D.; Neogi, T.; Silman, A.J.; Funovits, J.; Felson, D.T.; Bingham, C.O.; Birnbaum, N.S.; Burmester, G.R.; Bykerk, V.P.; Cohen, M.D.; Combe, B.; Costenbader, K.H.; Dougados, M.; Emery, P.; Ferraccioli, G.; Hazes, J.M.W.; Hobbs, K.; Huizinga, T.W.J.; Kavanaugh, A.; Kay, J.; Kvien, T.K.; Laing, T.; Mease, P.; Menard, H.A.; Moreland, L.W.; Naden, R.L.; Pincus, T.; Smolen, J.S.; Stanislawska-Biernat, E.; Symmons, D.; Tak, P.P.; Upchurch, K.S.; Vencovsky, J.; Wolfe, F. & Hawker, G. (2010), 2010 Rheumatoid Arthritis Classification Criteria An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative, Arthritis and Rheumatism 62(9): 2569-2581.
- Aletaha, D.; Neogi, T.; Silman, A.J.; Funovits, J.; Felson, D.T.; Bingham, C.O.; Birnbaum, N.S.; Burmester, G.R.; Bykerk, V.P.; Cohen, M.D.; Combe, B.; Costenbader, K.H.; Dougados, M.; Emery, P.; Ferraccioli, G.; Hazes, J.M.W.; Hobbs, K.; Huizinga, T.W.J.; Kavanaugh, A.; Kay, J.; Kvien, T.K.; Laing, T.; Mease, P.; Menard, H.A.; Moreland, L.W.; Naden, R.L.; Pincus, T.; Smolen, J.S.; Stanislawska-Biernat, E.; Symmons, D.; Tak, P.P.; Upchurch, K.S.; Vencovsky, J.; Wolfe, F. & Hawker, G. (2010), 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative, Annals of the Rheumatic Diseases 69(9): 1580-1588.
- Visser, K.; Allaart, C.F. & Huizinga, T.W.J. (2010), Use of methotrexate in undifferentiated arthritis, Clinical and Experimental Rheumatology 28(5): S117S121.
- Klarenbeek, N.B.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2010), Recent advances in the management of rheumatoid arthritis, British medical journal 341.
- Koevoets, R.; Allaart, C.F.; Heijde, D.M.F.M. van der & Huizinga, T.W.J. (2010), Disease Activity Monitoring in Rheumatoid Arthritis in Daily Practice: Experiences with METEOR, a Free Online Tool, Journal of Rheumatology 37(12): 2632-2633.
- Klarenbeek, N.B.; Guler-Yuksel, M.; Heijde, D.M.F.M. van der; Hulsmans, H.M.J.; Kerstens, P.J.S.M.; Molenaar, T.H.E.; Sonnaville, P.B.J. de; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2010), Clinical synovitis in a particular joint is associated with progression of erosions and joint space narrowing in that same joint, but not in patients initially treated with infliximab, Annals of the Rheumatic Diseases 69(12): 2107-2113.
- Nies, J.A.B. van; Marques, R.B.; Trompet, S.; Jong, Z. de; Kurreeman, F.A.S.; Toes, R.E.M.; Jukema, J.W.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2010), TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies, Arthritis Research and Therapy 12(2).
- Woude, D. van der; Syversen, S.W.; Voort, E.I.H. van der; Verpoort, K.N.; Goll, G.L.; Linden, M.P.M. van der; Helm-van Mil, A.H.M. van der; Heijde, D.M.F.M. van der; Huizinga, T.W.J.; Kvien, T.K. & Toes, R.E.M. (2010), The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis, Annals of the Rheumatic Diseases 69(6): 1110-1116.
- Feitsma, A.L.; Voort, E.I.H. van der; Franken, K.L.M.C.; Bannoudi, H. el; Elferink, B.G.; Drijfhout, J.W.; Huizinga, T.W.J.; Vries, R.R.P. de; Toes, R.E.M. & Ioan-Facsinay, A. (2010), Identification of Citrullinated Vimentin Peptides as T Cell Epitopes in HLA-DR4-Positive Patients With Rheumatoid Arthritis, Arthritis and Rheumatism 62(1): 117-125.
- Stahl, E.A.; Raychaudhuri, S.; Remmers, E.F.; Xie, G.; Eyre, S.; Thomson, B.P.; Li, Y.H.; Kurreeman, F.A.S.; Zhernakova, A.; Hinks, A.; Guiducci, C.; Chen, R.; Alfredsson, L.; Amos, C.I.; Ardlie, K.G.; Barton, A.; Bowes, J.; Brouwer, E.; Burtt, N.P.; Catanese, J.J.; Coblyn, J.; Coenen, M.J.H.; Costenbader, K.H.; Criswell, L.A.; Crusius, J.B.A.; Cui, J.; Bakker, P.I.W. de; Jager, P.L. de; Ding, B.; Emery, P.; Flynn, E.; Harrison, P.; Hocking, L.J.; Huizinga, T.W.J.; Kastner, D.L.; Ke, X.Y.; Lee, A.T.; Liu, X.D.; Martin, P.; Morgan, A.W.; Padyukov, L.; Posthumus, M.D.; Radstake, T.R.D.J.; Reid, D.M.; Seielstad, M.; Seldin, M.F.; Shadick, N.A.; Steer, S.; Tak, P.P.; Thomson, W.; Helm-van Mil, A.H.M. van der; Horst-Bruinsma, I.E. van der; Schoot, C.E. van der; Riel, P.L.C.M. van; Weinblatt, M.E.; Wilson, A.G.; Wolbink, G.J.; Wordsworth, B.P.; Wijmenga, C.; Karlson, E.W.; Toes, R.E.M.; Vries, N. de; Begovich, A.B.; Worthington, J.; Siminovitch, K.A.; Gregersen, P.K.; Klareskog, L.; Plenge, R.M.; BIRAC Consortium & YEAR Consortium (2010), Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci, Nature Genetics 42(6): 508U56.
- Helm-van Mil, A.H.M. van der; Toes, R.E.M. & Huizinga, T.W.J. (2010), Genetic variants in the prediction of rheumatoid arthritis, Annals of the Rheumatic Diseases 69(9): 1694-1696.
- Seddighzadeh, M.; Korotkova, M.; Kallberg, H.; Ding, B.; Daha, N.; Kurreeman, F.A.S.; Toes, R.E.M.; Huizinga, T.W.; Catrina, A.I.; Alfredsson, L.; Klareskog, L. & Padyukov, L. (2010), Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis, European Journal of Human Genetics 18(7): 821-826.
- Woude, D. van der; Dahlqvist, S.R.; Ioan-Facsinay, A.; Onnekink, C.; Schwarte, C.M.; Verpoort, K.N.; Drijfhout, J.W.; Huizinga, T.W.J.; Toes, R.E.M. & Pruijn, G.J.M. (2010), Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis, Annals of the Rheumatic Diseases 69(8): 1554-1561.
- Han, W.G.H.; Voort, E.I.H. van der; Bannoudi, H. el; Louis-Plence, P.; Huizinga, T.W.J. & Toes, R.E.M. (2010), DX5(+) CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4, European Journal of Immunology 40(10): 2731-2740.
- Hitchon, C.A.; Chandad, F.; Ferucci, E.D.; Willemze, A.; Ioan-Facsinay, A.; Woude, D. van der; Markland, J.; Robinson, D.; Elias, B.; Newkirk, M.; Toes, R.M.; Huizinga, T.W.J. & El-Gabalawy, H.S. (2010), Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives, Journal of Rheumatology 37(6): 1105-1112.
- Charbonnier, L.M.; Han, W.G.H.; Quentin, J.; Huizinga, T.W.J.; Zwerina, J.; Toes, R.E.M.; Jorgensen, C. & Louis-Plence, P. (2010), Adoptive transfer of IL-10-secreting CD4(+)CD49b(+) regulatory T cells suppresses ongoing arthritis, Journal of Autoimmunity 34(4): 390-399.
- Damjanovska, L.; Thabet, M.M.; Levarth, E.W.N.; Stoeken-Rijsbergen, G.; Voort, E.I. van der; Toes, R.E.M.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2010), Diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis, Annals of the Rheumatic Diseases 69(4): 730-732.
- Ioan-Facsinay, A.; El-Bannoudi, H.; Scherer, H.U.; Woude, D. van der; Menard, H.A.; Lora, M.; Trouw, L.A.; Huizinga, T.W.J. & Toes, R.E.M. (2010), ANTI-CCP ANTIBODIES ARE A COLLECTION OF ACPA THAT ARE CROSS-REACTIVE TO MULTIPLE CITRULLINATED ANTIGENS, Annals of the Rheumatic Diseases 69.
- Cui, J.; Saevarsdottir, S.; Thomson, B.; Padyukov, L.; Helm-van Mil, A.H.M. van der; Nititham, J.; Hughes, L.B.; Vries, N. de; Raychaudhuri, S.; Alfredsson, L.; Askling, J.; Wedren, S.; Ding, B.; Guiducci, C.; Wolbink, G.J.; Crusius, J.B.A.; Horst-Bruinsma, I.E. van der; Herenius, M.; Weinblatt, M.E.; Shadick, N.A.; Worthington, J.; Batliwalla, F.; Kern, M.; Morgan, A.W.; Wilson, A.G.; Isaacs, J.D.; Hyrich, K.; Seldin, M.F.; Moreland, L.W.; Behrens, T.W.; Allaart, C.F.; Criswell, L.A.; Huizinga, T.W.J.; Tak, P.P.; Bridges, S.L.; Toes, R.E.M.; Barton, A.; Klareskog, L.; Gregersen, P.K.; Karlson, E.W.; Plenge, R.M. & Biol Rheumatoid Arthrit Genet & Ge (2010), Rheumatoid Arthritis Risk Allele PTPRC Is Also Associated With Response to Anti-Tumor Necrosis Factor alpha Therapy, Arthritis and Rheumatism 62(7): 1849-1861.
- Klarenbeek, N.B.; Kooij, S.M. van der; Huizinga, T.J.W.; Goekoop-Ruiterman, Y.P.M.; Hulsmans, H.M.J.; Krugten, M.V. van; Speyer, I.; Vries-Bouwstra, J.K. de; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2010), Blood pressure changes in patients with recent-onset rheumatoid arthritis treated with four different treatment strategies: a post hoc analysis from the BeSt trial, Annals of the Rheumatic Diseases 69(7): 1342-1345.
- Visser, K.; Goekoop-Ruiterman, Y.P.M.; Vries-Bouwstra, J.K. de; Ronday, H.K.; Seys, P.E.H.; Kerstens, P.J.S.M.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2010), A matrix risk model for the prediction of rapid radiographic progression in patients with rheumatoid arthritis receiving different dynamic treatment strategies: post hoc analyses from the BeSt study, Annals of the Rheumatic Diseases 69(7): 1333-1337.
- Woude, D. van der; Lie, B.A.; Lundstrom, E.; Balsa, A.; Feitsma, A.L.; Houwing-Duistermaat, J.J.; Verduijn, W.; Nordang, G.B.N.; Alfredsson, L.; Klareskog, L.; Pascual-Salcedo, D.; Gonzalez-Gay, M.A.; Lopez-Nevot, M.A.; Valero, F.; Roep, B.O.; Huizinga, T.W.J.; Kvien, T.K.; Martin, J.; Padyukov, L.; Vries, R.R.P. de & Toes, R.E.M. (2010), Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations., Arthritis and Rheumatism 62(5): 1236-45.
- Goekoop, R.J.; Kloppenburg, M.; Kroon, H.M.; Frolich, M.; Huizinga, T.W.J.; Westendorp, R.G.J. & Gussekloo, J. (2010), Low innate production of interleukin-1beta and interleukin-6 is associated with the absence of osteoarthritis in old age., Osteoarthritis and Cartilage 18(7): 942-7.
- Emmer, B.J.; Veer, I.M.; Steup-Beekman, G.M.; Huizinga, T.W.J.; Grond, J. van der & Buchem, M.A. van (2010), Tract-Based Spatial Statistics on Diffusion Tensor Imaging in Systemic Lupus Erythematosus Reveals Localized Involvement of White Matter Tracts, Arthritis and Rheumatism 62(12): 3716-3721.
- Bertsias, G.K.; Ioannidis, J.P.A.; Aringer, M.; Bollen, E.; Bombardieri, S.; Bruce, I.N.; Cervera, R.; Dalakas, M.; Doria, A.; Hanly, J.G.; Huizinga, T.W.J.; Isenberg, D.; Kallenberg, C.; Piette, J.C.; Schneider, M.; Scolding, N.; Smolen, J.; Stara, A.; Tassiulas, I.; Tektonidou, M.; Tincani, A.; Buchem, M.A. van; Vollenhoven, R. van; Ward, M.; Gordon, C. & Boumpas, D.T. (2010), EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs, Annals of the Rheumatic Diseases 69(12): 2074-2082.
- Guler-Yuksel, M.; Allaart, C.F.; Watt, I.; Goekoop-Ruiterman, Y.P.M.; Vries-Bouwstra, J.K. de; Schaardenburg, D. van; Krugten, M.V. van; Dijkmans, B.A.C.; Huizinga, T.W.J.; Lems, W.F. & Kloppenburg, M. (2010), Treatment with TNF-alpha inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis, Osteoarthritis and Cartilage 18(10): 1256-1262.
- Yusuf, E.; Nelissen, R.G.; Ioan-Facsinay, A.; Stojanovic-Susulic, V.; DeGroot, J.; Osch, G. van; Middeldorp, S.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Association between weight or body mass index and hand osteoarthritis: a systematic review, Annals of the Rheumatic Diseases 69(4): 761-765.
- Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Suijlekom-Smit, L.W.A. van; Rossum, M.A.J. van; Hoppenreijs, E.P.A.H.; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2010), Clinical Course and Prognostic Value of Disease Activity in the First Two Years in Different Subtypes of Juvenile Idiopathic Arthritis, ARTHRITIS CARE & RESEARCH 62(2): 204-212.
- Bijsterbosch, J.; Wassenaar, M.J.E.; Cessie, S. le; Slagboom, P.E.; Rosendaal, F.R.; Huizinga, T.W.J. & Kloppenburg, M. (2010), Doyle Index is a valuable additional pain measure in osteoarthritis, Osteoarthritis and Cartilage 18(8): 1046-1050.
- Albers, H.M.; Brinkman, D.M.C.; Kamphuis, S.S.M.; Suijlekom-Smit, L.W.A. van; Rossum, M.A.J. van; Hoppenreijs, E.P.A.H.; Girschick, H.J.; Wouters, C.; Saurenmann, R.K.; Houwing-Duistermaat, J.J.; Huizinga, T.W.J.; Schilham, M.W. & Cate, R. ten (2010), Clinical course and prognostic value of disease activity in the first two years in different subtypes of juvenile idiopathic arthritis.
- Scherer, H.U.; Linden, M.P.M. van der; Kurreeman, F.A.S.; Stoeken-Rijsbergen, G.; Cessie, S. le; Huizinga, T.W.J.; Helm-van Mil, A.H. van der & Toes, R.E.M. (2010), Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis., Annals of the Rheumatic Diseases 69(3): 567-70.
- Scherer, H.U.; Woude, D. van der; Ioan-Facsinay, A.; Bannoudi, H. el; Trouw, L.A.; Wang, J.; Haupl, T.; Burmester, G.R.; Deelder, A.M.; Huizinga, T.W.J.; Wuhrer, M. & Toes, R.E.M. (2010), Glycan profiling of anti-citrullinated protein antibodies (ACPA) isolated from human serum and synovial fluid., Arthritis and Rheumatism.
- Scherer, H.U.; Linden, M.P.M. van der; Kurreeman, F.A.S.; Stoeken-Rijsbergen, G.; Cessie, S. le; Huizinga, T.W.J.; Helm-van Mil, A.H. van der & Toes, R.E.M. (2010), Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis, Annals of the Rheumatic Diseases 69(3): 567-570.
- Klarenbeek, N.B.; Guler-Yuksel, M.; Heijde, D.M.F.M. van der; Kerstens, P.J.S.M.; Mallee, C.; Westedt, M.L.; Huizinga, T.W.J.; Dijkmans, B.A.C. & Allaart, C.F. (2010), A comparison between the simplified erosion and narrowing score and the Sharp-van der Heijde score: post hoc analysis from the BeSt study., Annals of the Rheumatic Diseases.
- Smolen, J.S.; Landewe, R.; Breedveld, F.C.; Dougados, M.; Emery, P.; Gaujoux-Viala, C.; Gorter, S.; Knevel, R.; Nam, J.; Schoels, M.; Aletaha, D.; Buch, M.; Gossec, L.; Huizinga, T.; Bijlsma, J.W.J.W.; Burmester, G.; Combe, B.; Cutolo, M.; Gabay, C.; Gomez-Reino, J.; Kouloumas, M.; Kvien, T.K.; Martin-Mola, E.; McInnes, I.; Pavelka, K.; Riel, P. van; Scholte, M.; Scott, D.L.; Sokka, T.; Valesini, G.; Vollenhoven, R. van; Winthrop, K.L.; Wong, J.; Zink, A. & Heijde, D. van der (2010), EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs, Annals of the Rheumatic Diseases 69(6): 964-975.
- Scherer, H.U.; Woude, D. van der; Ioan-Facsinay, A.; Bannoudi, H. el; Trouw, L.A.; Wang, J.; Haupl, T.; Burmester, G.R.; Deelder, A.M.; Huizinga, T.W.J.; Wuhrer, M. & Toes, R.E.M. (2010), Glycan Profiling of Anti-Citrullinated Protein Antibodies Isolated From Human Serum and Synovial Fluid, Arthritis and Rheumatism 62(6): 1620-1629.
- Goekoop, R.J.; Kloppenburg, M.; Kroon, H.M.; Frolich, M.; Huizinga, T.W.J.; Westendorp, R.G.J. & Gussekloo, J. (2010), Low innate production of interleukin-1 beta and interleukin-6 is associated with the absence of osteoarthritis in old age, Osteoarthritis and Cartilage 18(7): 942-947.
- Goekoop-Ruiterman, Y.P.M. & Huizinga, T.W.J. (2010), Rheumatoid arthritis: can we achieve true drug-free remission in patients with RA?, Nature Reviews Rheumatology 6(2): 68-70.
- Klareskog, L.; Gregersen, P.K. & Huizinga, T.W.J. (2010), Prevention of autoimmune rheumatic disease: state of the art and future perspectives, Annals of the Rheumatic Diseases 69(12): 2062-2066.
- Linden, M.P.M. van der; Cessie, S. le; Raza, K.; Woude, D. van der; Knevel, R.; Huizinga, T.W.J. & Helm-van Mil, A.H.M. van der (2010), Long-Term Impact of Delay in Assessment of Patients With Early Arthritis, Arthritis and Rheumatism 62(12): 3537-3546.
- Kurreeman, F.A.S.; Goulielmos, G.N.; Alizadeh, B.Z.; Rueda, B.; Houwing-Duistermaat, J.; Sanchez, E.; Bevova, M.; Radstake, T.R.; Vonk, M.C.; Galanakis, E.; Ortego, N.; Verduyn, W.; Zervou, M.I.; Roep, B.O.; Dema, B.; Espino, L.; Urcelay, E.; Boumpas, D.T.; Berg, L.H. van den; Wijmenga, C.; Koeleman, B.P.C.; Huizinga, T.W.J.; Toes, R.E.M.; Martin, J.; AADEA Grp & SLEGEN Consortium (2010), The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases., Annals of the Rheumatic Diseases 69(4): 696-699.
- Kooloos, W.M.; Wessels, J.A.M.; Straaten, T. van der; Allaart, C.F.; Huizinga, T.W.J. & Guchelaar, H.J. (2010), Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis, Pharmacogenomics 11(2): 163-175.
- Vries, B. de; Steup-Beekman, G.M.; Haan, J.; Bollen, E.L.; Luyendijk, J.; Frants, R.R.; Terwindt, G.M.; Buchem, M.A. van; Huizinga, T.W.J.; Maagdenberg, A.M.J.M. van den & Ferrari, M.D. (2010), TREX1 gene variant in neuropsychiatric systemic lupus erythematosus, Annals of the Rheumatic Diseases 69(10): 1886-1887.
- Daha NA, Kurreeman FAS, Marques RB, Stoeken-Rijsbergen G, Verduijn W, Huizinga TWJ & Toes REM (2009), Confirmation of STAT4, IL2/IL21, and CTLA4 Polymorphisms in Rheumatoid Arthritis, Arthritis and Rheumatism 60(5): 1255-1260.
- Thabet MM, Huizinga TWJ, Marques RB, Stoeken-Rijsbergen G, Bakker AM, Kurreeman FA, White SJ, Toes REM & van der Helm-van Mil AHM (2009), Contribution of Fc gamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis, Annals of the Rheumatic Diseases 68(11): 1775-1780.
- Colzato LS, Huizinga M & Hommel B (2009), Recreational cocaine polydrug use impairs cognitive flexibility but not working memory., Psychopharmacology 207(2): 225-34.
- Albers HM, Kurreeman FAS, Stoeken-Rijsbergen G, Brinkman DMC, Kamphuis SSM, van Rossum MAJ, Girschick HJ, Wouters C, Saurenmann RK, Hoppenreijs E, Slagboom P, Houwing-Duistermaat JJ, Verduijn W, Huizinga TWJ, ten Cate R, Toes REM & Schilham MW (2009), Association of the Autoimmunity Locus 4q27 With Juvenile Idiopathic Arthritis, Arthritis and Rheumatism 60(3): 901-904.
- Emmer BJ, van der Bijl AE, Huizinga TW, Breedveld FC, Steens SC, Th Bosma GP, van Buchem MA & van der Grond J (2009), Brain involvement in rheumatoid arthritis: a magnetic resonance spectroscopy study., Arthritis and Rheumatism 60(11): 3190-5.
- Toes RE & Huizinga TW (2009), Autoimmune responses in the rheumatoid synovium.
- Thabet MM, Huizinga TW, Marques RB, Stoeken-Rijsbergen G, Bakker AM, Kurreeman FA, White SJ, Toes RE & van der Helm-van Mil AH (2009), Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis., Annals of the Rheumatic Diseases 68(11): 1775-80.
- Bijsterbosch J, Scharloo M, Visser AW, Watt I, Meulenbelt I, Huizinga TW, Kaptein AA & Kloppenburg M (2009), Illness perceptions in patients with osteoarthritis: change over time and association with disability., Arthritis and Rheumatism 61(8): 1054-61.
- de Boer IG, Peeters AJ, Ronday HK, Mertens BJA, Huizinga TWJ & Vlieland TPMV (2009), Assistive devices: usage in patients with rheumatoid arthritis, Clinical Rheumatology 28(2): 119-128.
- Toes REM & Huizinga TWJ (2009), Autoimmune Responses in the Rheumatoid Synovium, PLoS Medicine 6(1): 15-16.
- Scherer HU, Wang J, Toes REM, van der Woude D, Koeleman CAM, de Boer AR, Huizinga TWJ, Deelder AM & Wuhrer M (2009), Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum, PROTEOMICS - Clinical Applications 3(1): 106-115.
- van der Kooij SM, de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Ewals JAPM, Han KH, Hazes JMW, Kerstens PJSM, Peeters AJ, van Zeben D & Breedveld FC (2009), Patient-Reported Outcomes in a Randomized Trial Comparing Four Different Treatment Strategies in Recent-Onset Rheumatoid Arthritis, Arthritis and Rheumatism 61(1): 4-12.
- van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes RE, van der Heijde D, Huizinga TW & van der Helm-van Mil AH (2009), Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts., Arthritis and Rheumatism 60(8): 2262-71.
- Wang J, Huizinga TW & Toes RE (2009), De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid.
- Lebrec JJ, Huizinga TW, Toes RE, Houwing-Duistermaat JJ & van Houwelingen HC (2009), Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling., BMC Proceedings 3 Suppl 7: S94.
- van der Woude D, Houwing-Duistermaat JJ, Toes RE, Huizinga TW, Thomson W, Worthington J, van der Helm-van Mil AH & de Vries RR (2009), Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis., Arthritis and Rheumatism 60(4): 916-23.
- Han WG, Schuurhuis DH, Fu N, Camps M, van Duivenvoorde LM, Louis-Plence P, Franken KL, Huizinga TW, Melief CJ, Toes RE & Ossendorp F (2009), DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg., European Journal of Immunology 39(7): 1765-73.
- van der Linden MP, Feitsma AL, le Cessie S, Kern M, Olsson LM, Raychaudhuri S, Begovich AB, Chang M, Catanese JJ, Kurreeman FA, van Nies J, van der Heijde DM, Gregersen PK, Huizinga TW, Toes RE & van der Helm-Van Mil AH (2009), Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis., Arthritis and Rheumatism 60(8): 2242-7.
- Boersma C, de Groot AJ, Hovens JG, Huizinga TW, Steup-Beekman GM, van Buchem MA, van der Mast RC & van der Wee NJ (2009), [Psychiatric symptoms in systemic lupus erythematosus], Tijdschrift voor Psychiatrie 51(10): 773-7.
- Scherer HU, van der Linden MP, Kurreeman FA, Stoeken-Rijsbergen G, le Cessie S, Huizinga TW, van der Helm-van Mil AH & Toes RE. (2009), Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis., Annals of the Rheumatic Diseases.
- Jacobs JW, Huizinga TW, Bijlsma JW & Van der Helm-van Mil AH. (2009), Progress due to genetic research on rheumatoid arthritis: hype or hope?, Nederlands Tijdschrift voor Geneeskunde.
- (2009), Association between weight or Body Mass Index and hand osteoarthritis: a systematic review., Annals of the Rheumatic Diseases.
- (2009), Quality indicators in rheumatology:valid for whom?, Annals of the Rheumatic Diseases.
- van der Linden MP, Boja R, Klarenbeek NB, Huizinga TW, van der Heijde DM & van der Helm-van Mil AH (2009), Repair of joint erosions in rheumatoid arthritis: prevalence and patient characteristics in a large inception cohort., Annals of the Rheumatic Diseases.
- de Boer IG, Peeters AJ, Ronday HK, Mertens BJ, Huizinga TW & Vliet Vlieland TP (2009), Assistive devices: usage in patients with rheumatoid arthritis.
- Thabet MM, Huizinga TWJ, van der Heijde DM & van der Helm-van Mil AHM (2009), The prognostic value of baseline erosions in undifferentiated arthritis, Arthritis Research and Therapy 11(5).
- Heron M, Grutters JC, van Moorsel CHM, Ruven HJT, Huizinga TWJ, van der Helm-van Mil AHM, Claessen AME & van den Bosch JMM (2009), Variation in IL7R predisposes to sarcoid inflammation, Genes and Immunity 10(7): 647-653.
- Heron M, Grutters JC, van Moorsel CHM, Ruven HJT, Huizinga TWJ, van der Helm-van Mil AHM, Claessen AME & van den Bosch JMM (2009), Variation in IL7R predisposes to sarcoid inflammation, Genes and Immunity 10(7): 647-653.
- van der Helm-van Mil AHM & Huizinga TWJ (2009), The clinical relevance of a prediction rule for disease outcome in patients with undifferentiated arthritis: comment on the article by van der Helm-van Mil et al Reply, Arthritis and Rheumatism 60(7): 2209-2210.
- Klarenbeek NB, Allaart CF, Kerstens PJSM, Huizinga TWJ & Dijkmans BAC (2009), The BeSt story: on strategy trials in rheumatoid arthritis, Current Opinion in Rheumatology 21(3): 291-298.
- Huizinga TWJ & Grondal G (2009), Shared Symptoms in Rheumatic Diseases: a Blessing or a Curse?, Arthritis and Rheumatism 60(9): 2547-2549.
- van Bemmel JM, Huizinga TWJ & van der Helm-van Mil AHM (2009), No evidence yet to change American Heart Association recommendations for poststreptococcal reactive arthritis: comment on the article by van Bemmel et al Reply, Arthritis and Rheumatism 60(11): 3518-3519.
- Teng, Y.K.O.; Levarht, E.W.N.; Toes, R.E.M.; Huizinga, T.W.J. & Laar, J.M. van (2009), Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation, Annals of the Rheumatic Diseases 68(6): 1011-1016.
- Teng YKO, Levarht EWN, Toes REM, Huizinga TWJ & van Laar JM (2009), Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation, Annals of the Rheumatic Diseases 68(6): 1011-1016.
- Teng YKO, Levarht EWN, Toes REM, Huizinga TWJ & van Laar JM (2009), Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation, Annals of the Rheumatic Diseases 68(6): 1011-1016.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- Vlieland TPMV & Huizinga TWJ (2009), Quality indicators in rheumatology: valid for whom?, Annals of the Rheumatic Diseases 68(12): 1797-1799.
- van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes REM, van der Heijde D, Huizinga TWJ & van der Helm-van Mil AHM (2009), Prevalence of and Predictive Factors for Sustained Disease-Modifying Antirheumatic Drug-Free Remission in Rheumatoid Arthritis Results From Two Large Early Arthritis Cohorts, Arthritis and Rheumatism 60(8): 2262-2271.
- van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes REM, van der Heijde D, Huizinga TWJ & van der Helm-van Mil AHM (2009), Prevalence of and Predictive Factors for Sustained Disease-Modifying Antirheumatic Drug-Free Remission in Rheumatoid Arthritis Results From Two Large Early Arthritis Cohorts, Arthritis and Rheumatism 60(8): 2262-2271.
- van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes REM, van der Heijde D, Huizinga TWJ & van der Helm-van Mil AHM (2009), Prevalence of and Predictive Factors for Sustained Disease-Modifying Antirheumatic Drug-Free Remission in Rheumatoid Arthritis Results From Two Large Early Arthritis Cohorts, Arthritis and Rheumatism 60(8): 2262-2271.
- van der Woude D, Young A, Jayakumar K, Mertens BJ, Toes REM, van der Heijde D, Huizinga TWJ & van der Helm-van Mil AHM (2009), Prevalence of and Predictive Factors for Sustained Disease-Modifying Antirheumatic Drug-Free Remission in Rheumatoid Arthritis Results From Two Large Early Arthritis Cohorts, Arthritis and Rheumatism 60(8): 2262-2271.
- Kooloos WM, Wessels JAM, van der Kooij SM, Allaart CF, Huizinga TWJ & Guchelaar HJ (2009), Optimalisation of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A-677C alleles on probability to respond, Annals of the Rheumatic Diseases 68(8): 1371-1371.
- Kooloos WM, Wessels JAM, van der Kooij SM, Allaart CF, Huizinga TWJ & Guchelaar HJ (2009), Optimalisation of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A-677C alleles on probability to respond, Annals of the Rheumatic Diseases 68(8): 1371-1371.
- Kooloos WM, Wessels JAM, van der Kooij SM, Allaart CF, Huizinga TWJ & Guchelaar HJ (2009), Optimalisation of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A-677C alleles on probability to respond, Annals of the Rheumatic Diseases 68(8): 1371-1371.
- van Bemmel JM, Delgado V, Holman ER, Allaart CF, Huizinga TWJ, Bax JJ & van der Helm-van Mil AHM (2009), No Increased Risk of Valvular Heart Disease in Adult Poststreptococcal Reactive Arthritis, Arthritis and Rheumatism 60(4): 987-993.
- van Bemmel JM, Delgado V, Holman ER, Allaart CF, Huizinga TWJ, Bax JJ & van der Helm-van Mil AHM (2009), No Increased Risk of Valvular Heart Disease in Adult Poststreptococcal Reactive Arthritis, Arthritis and Rheumatism 60(4): 987-993.
- van Bemmel JM, Delgado V, Holman ER, Allaart CF, Huizinga TWJ, Bax JJ & van der Helm-van Mil AHM (2009), No Increased Risk of Valvular Heart Disease in Adult Poststreptococcal Reactive Arthritis, Arthritis and Rheumatism 60(4): 987-993.
- Mil AHMV, Huizinga TWJ & Raza K (2009), Mann-Whitney U test and Kruskal-Wallis test should be used for comparisons of differences in medians, not means: comment on the article by van der Helm-van Mil et al Reply, Arthritis and Rheumatism 60(5): 1565-1565.
- Mil AHMV, Huizinga TWJ & Raza K (2009), Mann-Whitney U test and Kruskal-Wallis test should be used for comparisons of differences in medians, not means: comment on the article by van der Helm-van Mil et al Reply, Arthritis and Rheumatism 60(5): 1565-1565.
- Bijsterbosch J, Scharloo M, Visser AW, Watt I, Mieulenbelt I, Huizinga TWJ, Kaptein AA & Kloppenburg M (2009), Illness Perceptions in Patients With Osteoarthritis: Change Over Time and Association With Disability, Arthritis and Rheumatism 61(8): 1054-1061.
- Bijsterbosch J, Scharloo M, Visser AW, Watt I, Mieulenbelt I, Huizinga TWJ, Kaptein AA & Kloppenburg M (2009), Illness Perceptions in Patients With Osteoarthritis: Change Over Time and Association With Disability, Arthritis and Rheumatism 61(8): 1054-1061.
- Bijsterbosch J, Scharloo M, Visser AW, Watt I, Mieulenbelt I, Huizinga TWJ, Kaptein AA & Kloppenburg M (2009), Illness Perceptions in Patients With Osteoarthritis: Change Over Time and Association With Disability, Arthritis and Rheumatism 61(8): 1054-1061.
- Trouw LA, Haisma EM, Levarht EW, van der Woude D, Ioan-Facsinay A, Daha MR, Huizinga TW & Toes RE (2009), Human anti-citrullinated protein antibodies (ACPA) not only activate the classical- but also the alternative complement pathway, Molecular Immunology 46(14): 2828-2828.
- Trouw LA, Haisma EM, Levarht EW, van der Woude D, Ioan-Facsinay A, Daha MR, Huizinga TW & Toes RE (2009), Human anti-citrullinated protein antibodies (ACPA) not only activate the classical- but also the alternative complement pathway, Molecular Immunology 46(14): 2828-2828.
- van der Laan-Baalbergen NE, Mollema SA, Kritikos H, Schoe A, Huizinga TWJ, Bax JJ, Boumpas DT & van Laar JM (2009), Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus, Netherlands Journal of Medicine 67(9): 295-301.
- van der Laan-Baalbergen NE, Mollema SA, Kritikos H, Schoe A, Huizinga TWJ, Bax JJ, Boumpas DT & van Laar JM (2009), Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus, Netherlands Journal of Medicine 67(9): 295-301.
- van der Laan-Baalbergen NE, Mollema SA, Kritikos H, Schoe A, Huizinga TWJ, Bax JJ, Boumpas DT & van Laar JM (2009), Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus, Netherlands Journal of Medicine 67(9): 295-301.
- van der Laan-Baalbergen NE, Mollema SA, Kritikos H, Schoe A, Huizinga TWJ, Bax JJ, Boumpas DT & van Laar JM (2009), Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus, Netherlands Journal of Medicine 67(9): 295-301.
- Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG, Barton A, Bowes J, Burtt NP, Chang M, Coblyn J, Costenbader KH, Criswell LA, Crusius JBA, Cui J, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TWJ, Kastner DL, Ke XY, Kurreeman FAS, Lee AT, Liu XD, Li YH, Martin P, Morgan AW, Padyukov L, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AHM, van der Horst-Bruinsma IE, Weinblatt ME, Wilson AG & Wolbink GJ (2009), Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk, Nature Genetics 41(12): 1313U76.
- van Bergen J, Kooy-Winkelaar EMC, van Dongen H, van Gaalen FA, Thompson A, Huizinga TWJ, Feltkamp MCW, Toes REM & Koning F (2009), Functional Killer Ig-Like Receptors on Human Memory CD4(+) T Cells Specific for Cytomegalovirus, Journal of Immunology 182(7): 4175-4182.
- van der Woude D & Huizinga TWJ (2009), Every shared epitope allele for itself?, Nature Reviews Rheumatology 5(9): 477-478.
- van der Woude D & Huizinga TWJ (2009), Every shared epitope allele for itself?, Nature Reviews Rheumatology 5(9): 477-478.
- Bertsias GK, Ioannidis JPA, Boletis J, Bombardieri S, Cervera R, Dostal C, Font J, Gilboe IM, Houssiau F & Huizinga T (2009), EULAR points to consider for conducting clinical trials in systemic lupus erythematosus: literature based evidence for the selection of endpoints, Annals of the Rheumatic Diseases 68(4): 477-483.
- Gordon C, Bertsias G, Ioannidis JPA, Boletis J, Bombardieri S, Cervera R, Dostal C, Font J, Gilboe IM & Houssiau F (2009), EULAR points to consider for conducting clinical trials in systemic lupus erythematosus, Annals of the Rheumatic Diseases 68(4): 470-476.
- Bijl, A.E. van der; Teng, Y.K.O.; Oosterhout, M. van; Breedveld, F.C.; Allaart, C.F. & Huizinga, T.W.J. (2009), Efficacy of Intraarticular Infliximab in Patients With Chronic or Recurrent Gonarthritis: A Clinical Randomized Trial, Arthritis and Rheumatism 61(7): 974-978.
- van der Kooij SM, Goekoop-Ruiterman YPM, de Vries-Bouwstra JK, Guler-Yuksel M, Zwinderman AH, Kerstens PJSM, van der Lubbe PAHM, de Beus WM, Grillet BAM, Ronday HK, Huizinga TWJ, Breedveld FC, Dijkmans BAC & Allaart CF (2009), Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis, Annals of the Rheumatic Diseases 68(6): 914-921.
- Wang J, Huizinga TWJ & Toes REM (2009), De Novo Generation and Enhanced Suppression of Human CD4(+)CD25(+) Regulatory T Cells by Retinoic Acid, Journal of Immunology 183(6): 4119-4126.
- Han, W.G.H.; Schuurhuis, D.H.; Fu, N.; Camps, M.; Duivenvoorde, L.M. van; Louis-Plence, P.; Franken, K.L.M.C.; Huizinga, T.W.J.; Melief, C.J.M.; Toes, R.E.M. & Ossendorp, F. (2009), DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg, European Journal of Immunology 39(7): 1765-1773.
- Kooloos WM, Wessels JAM, van der Straaten T, Huizinga TWJ & Guchelaar HJ (2009), Criteria for the selection of single nucleotide polymorphisms in pathway pharmacogenetics: TNF inhibitors as a case study, Drug Discovery Today 14(17-18): 837-844.
- Kooloos WM, Guchelaar HJ, Huizinga TWJ & Wessels JAM (2009), Comment on: Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate, Rheumatology 48(9): 1176-1177.
- Emmer BJ, van der Bijl AE, Huizinga TWJ, Breedveld FC, Steens SCA, Bosma GPT, van Buchem MA & van der Grond J (2009), Brain Involvement in Rheumatoid Arthritis A Magnetic Resonance Spectroscopy Study, Arthritis and Rheumatism 60(11): 3190-3195.
- Kurreeman FAS, Daha NA, Chang M, Catanese JJ, Begovich AB, Huizinga TWJ & Toes REM (2009), Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population, Annals of the Rheumatic Diseases 68(11): 1789-1790.
- van der Linden MPM, Feitsma AL, le Cessie S, Kern M, Olsson LM, Raychaudhuri S, Begovich AB, Chang M, Catanese JJ, Kurreeman FAS, van Nies J, van der Heijde DM, Gregersen PK, Huizinga TWJ, Toes REM & van der Helm-van Mil AHM (2009), Association of a Single-Nucleotide Polymorphism in CD40 With the Rate of Joint Destruction in Rheumatoid Arthritis, Arthritis and Rheumatism 60(8): 2242-2247.
- de Vries B, Steup-Beekman GM, Terwindt GM, Haan J, Boon EMJ, Huizinga TWJ, Frants RR, Ferrari MD & van den Maagdenberg AMJM (2009), A role of the TREX1 gene in disorders that are comorbid with migraine?, Cephalalgia 29: 82-82.
- Trouw LA, Haisma EM, Levarht EWN, van der Woude D, Ioan-Facsinay A, Daha VR, Huizinga TWJ & Toes RE (2009), Anti-Cyclic Citrullinated Peptide Antibodies From Rheumatoid Arthritis Patients Activate Complement via Both the Classical and Alternative Pathways, Arthritis and Rheumatism 60(7): 1923-1931.
- Hitchon C, Chandad F, Ferucci E, Willemze A, Ioan-Facsinay A, Peschken C, Robinson D, Elias B, Newkirk M, Huizinga T & El-Gabalawy H (2009), Antibodies to Porphyromonas Gingivalis Are Associated with Anti-citrullinated Protein Antibodies (ACPA) in RA Patients and Their Relatives, Journal of Rheumatology 36(11): 2572-2573.
- van der Helm-van Mil AHM, Huizinga TWJ & Raza K (2009), The clinical utility of a rule for predicting rheumatoid arthritis in patients with early undifferentiated arthritis: comment on the article by van der Helm-van Mil et al Reply, Arthritis and Rheumatism 60(3): 906-906.
- Albers HM, Kurreeman FA, Stoeken-Rijsbergen G, Brinkman DM, Kamphuis SS, van Rossum MA, Girschick HJ, Wouters C, Saurenmann RK, Hoppenreijs E, Slagboom P, Houwing-Duistermaat JJ, Verduijn W, Huizinga TW, Ten Cate R, Toes RE & Schilham MW (2009), Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis., Arthritis and Rheumatism 60(3): 901-4.
- van der Linden MPM, van der Woude D, Ioan-Facsinay A, Levarht EWN, Stoeken-Rijsbergen G, Huizinga TWJ, Toes REM & van der Helm-van Mil AHM (2009), Value of Anti-Modified Citrullinated Vimentin and Third-Generation Anti-Cyclic Citrullinated Peptide Compared With Second-Generation Anti-Cyclic Citrullinated Peptide and Rheumatoid Factor in Predicting Disease Outcome in Undifferentiated Arthritis and Rheumatoid Arthritis, Arthritis and Rheumatism 60(8): 2232-2241.
- Trouw LA, Haisma EM, Levarht EW, van der Woude D, Ioan-Facsinay A, Daha MR, Huizinga TW & Toes RE (2009), Human anti-citrullinated protein antibodies (ACPA) not only activate the classical- but also the alternative complement pathway, Molecular Immunology 46(14): 2828-2828.
- Laan-Baalbergen, N.E. van der; Mollema, S.A.; Kritikos, H.; Schoe, A.; Huizinga, T.W.J.; Bax, J.J.; Boumpas, D.T. & Laar, J.M. van (2009), Heart failure as presenting manifestation of cardiac involvement in systemic lupus erythematosus, Netherlands Journal of Medicine 67(9): 295-301.
- Albers HM, Wessels JAM, van der Straaten RJHM, Brinkman DMC, Suiilekom-Smit LWA, Kamphuis SSM, Girschick HJ, Wouters C, Schilham MW & le Cessie S (2009), Time to Treatment as an Important Factor for the Response to Methotrexate in Juvenile Idiopathic Arthritis, Arthritis and Rheumatism 61(1): 46-51.
- Bijsterbosch J, Visser W, Kroon H, Stamm T, Meulenbelt I, Huizinga T & Kloppenburg M (2009), PAIN AND FUNCTIONAL DISABILITY IN SYMPTOMATIC HAND OSTEOARTHRITIS DEPEND ON TYPE OF JOINT INVOLVEMENT, Osteoporosis International 20: 80-80.
- Lebrec JJP, Nishchenko I, van der Wijk HJ, Hulizinga TW & van Houwelingen HC (2009), A Polygenic Model for Integration of Linkage and Pathway Information, Genetic Epidemiology 33(3): 198-206.
- Damjanovska L, Thabet MM, Levarht EW, Stoeken-Rijsbergen G, van der Voort EI, Toes RE, Huizinga TW & van der Helm-van Mil AH. (2009), The diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis. , Annals of the Rheumatic Diseases.
- van der Woude D, Houwing-Duistermaat JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2009), Quantitative Heritability of Anti-Citrullinated Protein Antibody-Positive and Anti-Citrullinated Protein Antibody-Negative Rheumatoid Arthritis, Arthritis and Rheumatism 60(4): 916-923.
- Vlieland TPMV & Huizinga TWJ (2009), Quality indicators in rheumatology: valid for whom?, Annals of the Rheumatic Diseases 68(12): 1797-1799.
- Bertsias G, Ioannidis JPA, Boletis J, Bombardieri S, Cervera R, Dostal C, Font J, Gilboe IM, Houssiau F, Huizinga T, Isenberg D, Kallenberg CGM, Khamashta M, Piette JC, Schneider M, Smolen J, Sturfelt G, Tincani A, van Vollenhoven R, Gordon C & Boumpas DT (2008), EULAR recommendations for the management of systemic lupus erythematosus. Report of a task force of the EULAR standing committee for international clinical studies including therapeutics, Annals of the Rheumatic Diseases 67(2).
- van der Helm-van Mil AHM & Huizinga TWJ (2008), Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets, Arthritis Research and Therapy 10(2).
- Van Der Kooij SM, Wessels JAM, Huizinga TWJ & Guchelaar HJ (2008), Comment on: The pharmacogenetics of methotrexate, Rheumatology 47(4).
- Tchetverikov I, Kraan MC, van El B, Hanemaaijer R, DeGroot J & Huizinga TWJ (2008), Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with alpha(2) macroglobulin in serum of rheumatoid arthritis patients, Annals of the Rheumatic Diseases 67(1).
- Gelinck LBS, van der Bijl AE, Beyer WEP, Visser LG, Huizinga TWJ, van Hogezand RA, Rimmelzwaan GF & Kroon FP (2008), The effect of anti-tumour necrosis factor alpha treatment on the antibody response to influenza vaccination, Annals of the Rheumatic Diseases 67(5).
- Lebrec JJP, Nishchenko I, van der Wijk HJ, Huizinga TW & van Houwelingen HC (2008), A polygenic model for integration of linkage and pathway information, Annals of Human Genetics 72.
- van der Helm-van Mil AHM, van der Kooij SM, Allaart CF, Toes REM & Huizinga TWJ (2008), A high body mass index has a protective effect on the amount of joint destruction in small joints in early rheumatoid arthritis, Annals of the Rheumatic Diseases 67(6).
- Gelinck LBS, Van der Bijl AE, Visser LG, Huizinga TWJ, Van Hogezand RA, Rijkers GT & Kroon FP (2008), Synergistic immunosuppressive effect of anti-TNF combined with methotrexate on antibody responses to the 23 valent pneumococcal polysaccharide vaccine, Vaccine 26(27-28).
- Wessels JAM, van der Kooij SM, Huizinga TWJ & Guchelaar HJ (2008), Identity of single-nucleotide polymorphisms used in a clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy: comment on the article by Wessels et al - Reply, Arthritis and Rheumatism 58(4).
- Rood MJ & Huizinga TWJ (2008), Vascular compromise of a finger due to tenosynovitis, Journal of Rheumatology 35(2).
- de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Verpoort KN, Schreuder GMT, Ewals JAPM, Terwiel JP, Ronday HK, Kerstens PJSM, Toes REM, de Vries RRP, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Allaart CF (2008), Progression of joint damage in early rheumatoid arthritis, Arthritis and Rheumatism 58(5).
- Visser K, Verpoort KN, van Dongen H, van der Kooij SM, Allaart CF, Toes REM, Huizinga TWJ & Mil AHMVDHV (2008), Pretreatment serum levels of anti-cyclic citrullinated peptide antibodies are associated with the response to methotrexate in recent-onset arthritis, Annals of the Rheumatic Diseases 67(8).
- Botha-Scheepers S, Watt I, Slagboom E, de Craen AJM, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2008), Innate production of tumour necrosis factor alpha and interleukin 10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 67(8).
- Heemstra KA, Toes RE, Sepers J, Pereira AM, Corssmit EP, Huizinga TWJ, Romijn JA & Smit JW (2008), Rituximab in relapsing Graves' disease, a phase II study, European Journal of Endocrinology 159(5).
- De Poorter JJ, Hoeben RC, Hogendoorn S, Mautner V, Ellis J, Obermann WR, Huizinga TWJ & Nelissen RGHH (2008), Gene therapy and cement injection for restabilization of loosened hip prostheses, Human Gene Therapy 19(1).
- Willemze A, Ioan-Facsinay A, Robinson D, Peschken C, Markland J, Fritzler M, Newkirk M, Menard H, Elias B, Toes R, Huizinga T & El-Gabalawy H (2008), Isotype usage and fine specificity of anti-citrullunated protein antibodies and rheumatoid factor in first nations RA patients and their first degree relatives: New insights into RA onset, Journal of Rheumatology 35(6).
- van der Woude D & Huizinga TWJ (2008), Translating basic research into clinical rheumatology, Best Practice and Research: Clinical Rheumatology 22(2).
- Ioan-Facsinay A, Willemze A, Robinson DB, Peschken CA, Markland J, van der Woude D, Elias B, Menard HA, Newkirk M, Fritzler MJ, Toes REM, Huizinga TWJ & El-Gabalawy HS (2008), Marked Differences in Fine Specificity and Isotype Usage of the Anti-Citrullinated Protein Antibody in Health and Disease, Arthritis and Rheumatism 58(10).
- van Bemmel J, Delgado V, Holman E, Allaart C, Huizinga T, Bax J & Mil AHV (2008), No increased risk on valvular heart disease in adult post-streptococcal reactive arthritis, Arthritis and Rheumatism 58(9).
- van der Woude D, Visser K, Brand R, Klarenbeek NB, van der Linden MPM, Mailee C, de Beus WM, Kerstens PJSM, Dijkmans BAC, Huizinga TWJ, Mil AHMVDHV & Allaart CF (2008), Improved outcomes of drug-free remission with DAS-steered therapy compared to conventional therapy for rheumatoid arthritis, Arthritis and Rheumatism 58(9).
- Guler-Yuksel M, Klarenbeek NB, Gerards AH, van Krugten MV, Ronday HK, Huizinga TWJ, Dijkmans BAC, Allaarti CF & Lems WF (2008), Cortical hand bone mineral density (BMD) loss as predictor of progressive joint damage in recent-onset rheumatoid arthritis (RA), Arthritis and Rheumatism 58(9).
- Van der Helm-van Mil AH, Detert J, le Cessie S, Filer A, Bastian H, Burmester G, Huizinga TWJ & Raza K (2008), Towards personalized medicine in rheumatology - A prediction rule for the development of rheumatoid arthritis in patients with undifferentiated arthritis, Arthritis and Rheumatism 58(9).
- Klarenbeek NB, Guler-Yuksel M, van der Kooij SM, van der Heijde DMFM, Han KH, Hulsmans HMJ, Kerstens PJSM, Speyer I, Huizinga TWJ, Dijkmans BAC & Allaart CF (2008), Clinical and radiological outcomes in recent onset rheumatoid arthritis after 5 years of DAS-steered treatment in the BeSt-Study, Arthritis and Rheumatism 58(9).
- van der Woude D, Ioan-Facsinay A, Schwarte C, Stoeken-Rijsbergen G, Onnekink C, Drijfhout JW, Huizinga TWJ, Toes REM & Pruijn GJM (2008), Fine specificity of the anti-citrullinated protein antibody response in relationship to the disease course of rheumatoid arthritis, Arthritis and Rheumatism 58(9).
- Hurkmans EJ, Li LC, Huizinga TWJ & Vlieland TPMV (2008), Exercise therapy in rheumatoid arthritis: How confident are physical therapists regarding their knowledge and skills?, Arthritis and Rheumatism 58(9).
- Scherer HU, van der Woude D, Koeleman CA, de Boer AR, Huizinga TWJ, Deelder AM, Wuhrer M & Toes REM (2008), Glycan profiling of anti-citrullinated protein antibodies (ACPA) reveals profound differences in glycosylation between ACPA and serum, Arthritis and Rheumatism 58(9).
- Bijsterbosch J, Visser AW, Kroon HM, Huizinga TWJ & Kloppenburg M (2008), Pain and functional disability in symptomatic hand osteoarthritis depend on type of joint involvement, Arthritis and Rheumatism 58(9).
- Zan M, Shipman E, Burns C, Collins J, Teng O, Levarht N, Huizinga T, Silverman G, Laar J & Rigby W (2008), The effect of gender, rheumatoid arthritis (RA) and biologic therapy on anti-phosphorylcholine antibody (APCA) levels, Arthritis and Rheumatism 58(9).
- Albers H, Kurreeman F, Houwing-Duistermaat J, Brinkman D, Kamphuis S, Girschick H, Wouters C, van Rossum M, Verduyn W, Toes R, Huizinga T, Schilham M & ten Cate R (2008), The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis, Arthritis and Rheumatism 58(9).
- Hitchon CA, Chandad F, Ferucci E, Willemze A, Ioan-Facsinay A, Robinson D, Elias B, Newkirk M, Huizinga T & El-Gabalawy HS (2008), Antibodies to p. gingivalis are associated with anti-citrullinated protein antibodies (ACPA) in RA patients and their relatives, Arthritis and Rheumatism 58(9).
- Trujillo AM, Van Rietschoten JGI, Timmer TCG, Kraan TCTM, Huizinga TWJ, Tak PP & Verweij CL (2008), Loss of imprinting of IGF2 characterizes low inflammatory type of FLS in rheumatoid arthritis, Arthritis and Rheumatism 58(9).
- van der Woude D, Holiwing-Duistermak JJ, Toes REM, Huizinga TWJ, Thomson W, Worthington J, van der Helm-van Mil AHM & de Vries RRP (2008), Quantitative heritability and contribution of predisposing HLA Alleles to ACPA-positive and ACPA-negative rheumatoid arthritis, Arthritis and Rheumatism 58(9).
- Kurreeman FAS, Rocha D, Houwing-Duistermaat J, Vrijmoet S, Teixeira VH, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Vaz C, Fernandes M, Pascual-Saicedo D, Michou L, Bombardieri S, Radstake T, van Riel P, van de Putte L, Lopes-Vaz A, Prum B, Bardin T, Gut I, Cornelis F, Huizinga TWJ, Petit-Teixeira E & Toes REM (2008), Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a European family-based study, Arthritis and Rheumatism 58(9).
- Mil AHMVDHV, Padyukov L, Toes RM, Klareskog L & Huizinga TWJ (2008), Genome-wide single-nucleotide polymorphism studies in rheumatology: Hype or hope?, Arthritis and Rheumatism 58(9).
- van Mierlo GJD, Scherer HU, Hameetman M, Morgan ME, Flierman R, Huizinga TWJ & Toes REM (2008), Cutting edge: TNFR-Shedding by CD4(+)CD25(+) regulatory T cells inhibits the induction of inflammatory mediators, Journal of Immunology 180(5).
- Chang M, Saiki RK, Cantanese JJ, Lew D, van der Helm-van Mil AHM, Toes REM, Huizinga TWJ, Ardlie KG, Criswell LA, Seldin MF, Amos CI, Kastner DL, Gregersen PK, Schrodi SJ & Begovich AB (2008), The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis, Arthritis and Rheumatism 58(6).
- Tchetverikov I, Huizinga TWJ & van der Helm-van Mil AHM (2008), Biomarkers in the prediction of radiographic progression in early rheumatoid arthritis: comment on the article by Young-Min et al, Arthritis and Rheumatism 58(5).
- Emmer BJ, Steup-Beekman GM, Steens SCA, Huizinga TWJ, van Buchem MA & van der Grond J (2008), Correlation of magnetization transfer ratio histogram parameters with neuropsychiatric systemic lupus erythematosus criteria and proton magnetic resonance spectroscopy, Arthritis and Rheumatism 58(5).
- Wessels JAM, Huizinga TWJ & Guchelaar HJ (2008), Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis, Rheumatology 47(3).
- Feitsma A, Worthington J, Var der Helm-Van Mil A, Plant D, Thomson W, Ursum J, Van Schaardenburg D, Van Der Horst-Bruinsma I, Van Rood J, Huizinga T, Toes R & De Vries R (2008), Protective effect of non-inherited maternal HLA-DR antigens on rheumatoid arthritis development, Annals of the Rheumatic Diseases 67.
- Kurreeman F, Padyukov L, Marques R, Schrodi S, Seddighzadeh M, Stoeken-Rijsbergen G, Van der Helm-Van Mil A, Allaart C, Verduyn W, Housing-Duistermaat J, Alsfredsson L, Begovich A, Petit-Texeira E, Cornelis F, Klareskog L, Huizinga T & Toes R (2008), Association and linkage of the TRAF1/C5 region with specific subsets of rheumatoid arthritis, Annals of the Rheumatic Diseases 67.
- Thabet M, Van der Helm-Van Mil A, Marques R, Bakker A, White S, Houwing-Duistermaat J, Toes R & Huizinga T (2008), Lower copy number of FC gamma receptor 3B gene is associated with rheumatoid arthritis, Annals of the Rheumatic Diseases 67.
- Charbonnier LM, Han W, Quentin J, Huizinga T, Toes R, Jorgensen C & Louis-Plence P (2008), Adoptive transfer of CD4+CD49b+ regulatory T cells expanded by immature dendritic cells reverse symptoms of established arthritis, Annals of the Rheumatic Diseases 67.
- Scherer H, Van Mierlo G, Hameetman M, Morgan M, Flierman R, Huizinga T & Toes R (2008), CD4+CD25+ regulatory T cells directly inhibit inflammation by shedding of sTNFRII, Annals of the Rheumatic Diseases 67.
- Ioan-Facsinay A, Willemze A, Robinson D, Peschken C, Markland J, Elias B, Menard H, Newkirk M, Fritzler M, Toes R, Huizinga T & El-Gabalawy H (2008), Marked differences in fine-specificity and isotype usage of the anti-citrulline response in health and disease, Annals of the Rheumatic Diseases 67.
- van Oosterhout M, Bajema I, Levarht EWN, Toes REM, Huizinga TWJ & van Laar JM (2008), Differences in synovial tissue infiltrates between anti-cyclic citrullinated peptide-positive rheumatoid arthritis and anti-cyclic citrullinated peptide-negative rheumatoid arthritis, Arthritis and Rheumatism 58(1).
- de Poorter JJ, Hoeben RC, Obermann WR, Huizinga TWJ & Nelissen RGHH (2008), Gene Therapy for the Treatment of Hip Prosthesis Loosening: Adverse Events in a Phase 1 Clinical Study, Human Gene Therapy 19(10): 1029-1038.
- de Poorter JJ, Hoeben RC, Obermann WR, Huizinga TWJ & Nelissen RGHH (2008), Gene Therapy for the Treatment of Hip Prosthesis Loosening: Adverse Events in a Phase 1 Clinical Study, Human Gene Therapy 19(10): 1029-1038.
- Feitsma AL, van der Helm-van Mil AHM, Huizinga TWJ, de Vries RRP & Toes REM (2008), Protection against rheumatoid arthritis by HLA: nature and nurture, Annals of the Rheumatic Diseases 67.
- van der Woude D, Young A, Brand R, Toes REM, Huizinga TWJ & Mil AHMVDHV (2008), Prevalence and predictive factors for DMARD-free remission in RA: Lessons from two large early arthritis cohorts, Arthritis and Rheumatism 58(9).
- Rood MJ, van Laar JM, de Schepper AM & Huizinga TW (2008), The Milwaukee shoulder/knee syndrome, JCR: Journal of Clinical Rheumatology 14(4).
- Wang J, van Dongen H, Scherer HU, Huizinga TWJ & Toes REM (2008), Suppressor activity among CD4+,CD25++ T cells is discriminated by membrane-bound tumor necrosis factor alpha, Arthritis and Rheumatism 58(6).
- Huizinga TWJ & Diamond B (2008), Lupus and the central nervous system, Lupus 17(5).
- Rood MJ, Vermeer MH & Huizinga TWJ (2008), Hyperpigmentation of the skin due to hydroxychloroquine, Scandinavian Journal of Rheumatology 37(2).
- de Poorter JJ, Hoeben RC, Obermann WR, Huizinga TWJ & Nelissen RGHH (2008), Gene Therapy for the Treatment of Hip Prosthesis Loosening: Adverse Events in a Phase 1 Clinical Study, Human Gene Therapy 19(10): 1029-1038.
- Machold KP, Landewe R, Smolen JS & Huizinga TWJ (2008), Limited Efficacy of Glucocorticoids in Very Early Arthritis Results of the Stop Arthritis Very Early (SAVE) Trial, an International Multi-center, Randomized, Double-blind, Placebo-controlled Clinical Trial, Arthritis and Rheumatism 58(12).
- Houwing-Duistermaat JJ, van der Woude D, Toes REM, Huizinga TWJ, van der Helm-van Mil AHM & de Vries RRP (2008), Estimation of the heritability and the contribution of known genetic factors from twin data applied to Rheumatoid Arthritis, Genetic Epidemiology 32(7).
- van der Helm-van Mil AHM, Huizinga TWJ, de Vries RRP & Toes REM (2008), Tic-tac-toe does not provide lessons for appreciating the HLA-rheumatoid arthritis relationship: comment on the editorial by Bridges et al, Arthritis and Rheumatism 58(11).
- Chang M, Rowland CM, Garcia VE, Schrodi SJ, Catanese JJ, Mil AHMVDHV, Ardlie KG, Amos CI, Criswell LA, Kastner DL, Gregersen PK, Kurreeman FAS, Toes REM, Huizinga TWJ, Seldin MF & Begovich AB (2008), A Large-Scale Rheumatoid Arthritis Genetic Study Identifies Association at Chromosome 9q33.2, PLoS Genetics 4(6).
- Albers HM, Kurreeman FAS, Houwing-Duistermaat JJ, Brinkman DMC, Kamphuis SSM, Girschick HJ, Wouters C, Van Rossum MAJ, Verduijn W, Toes REM, Huizinga TWJ, Schilham MW & ten Cate R (2008), The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis, Annals of the Rheumatic Diseases 67(11).
- Raychaudhuri S, Remmers EF, Lee AT, Hackett R, Guiducci C, Burtt NP, Gianniny L, Korman BD, Padyukov L, Kurreeman FAS, Chang M, Catanese JJ, Ding B, Wong S, Mil AHMV, Neale BM, Coblyn J, Cui J, Tak PP, Wolbink GJ, Crusius JBA, van der Horst-Bruinsma IE, Criswell LA, Amos CI, Seldin MF, Kastner DL, Ardlie KG, Alfredsson L, Costenbader KH, Altshuler D, Huizinga TWJ, Shadick NA, Weinblatt ME, de Vries N, Worthington J, Seielstad M, Toes REM, Karlson EW, Begovich AB, Klareskog L, Gregersen PK, Daly MJ & Plenge RM (2008), Common variants at CD40 and other loci confer risk of rheumatoid arthritis, Nature Genetics 40(10).
- Helm-van Mil AHMV, Detert J, le Cessie S, Filer A, Bastian H, Burmester GR, Huizinga TWJ & Raza K (2008), Validation of a prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis, Arthritis and Rheumatism 58(8).
- Teng, Y.; Levarht, N.; Bajema, I.; Toes, R.; Huizinga, T. & Laar, J. van (2007), Recruitment of B lymphocytes into the periphery is associated with disease activity in patients with refractory rheumatoid arthritis, Annals of the Rheumatic Diseases 66.
- van der Woude D & Huizinga TWJ (2007), The battle between anti-cyclic citrullinated peptide and rheumatoid factor tests - a winner at last?, Nature Clinical Practice Rheumatology 3(12).
- Teng YKO, Hashemi M, Levahrt NL, Toes REM, Huizinga TWJ & van Laar JM (2007), Recruitment of B lymphocytes into the periphery is associated with disease activity in patients with refractory rheumatoid arthritis, Annals of the Rheumatic Diseases 66.
- Timmer TCG, Baltus B, Vondenhoff M, Huizinga TWJ, Tak PP, Verweij CL, Mebius RE & Kraan TCTMV (2007), Inflammation and ectopic lymphoid structures in rheumatoid arthritis synovial tissues dissected by genomics technology - Identification of the interleukin-7 signaling pathway in tissues with lymphoid neogenesis, Arthritis and Rheumatism 56(8).
- Montfoort, N. van; Jong, J.M.H. de; Schuurhuis, D.H.; Voort, E.I.H. van der; Camps, M.G.M.; Huizinga, T.W.J.; Kooten, C. van; Daha, M.R.; Verbeek, J.S.; Ossendorp, F. & Toes, R.E.M. (2007), A novel role of complement factor C1q in augmenting the presentation of antigen captured in immune complexes to CD8+T lymphocytes, Journal of Immunology 178(12).
- van Dongen H, van Aken J, Lard LR, Visser K, Ronday HK, Hulsmans HMJ, Speyer I, Westedt ML, Peeters AJ, Allaart CF, Toes REM, Breedveld FC & Huizinga TWJ (2007), The probable rheumatoid arthritis: Methotrexate versus placebo treatment (the prompt) study: A double-blind randomized controlled trial, Annals of the Rheumatic Diseases 66.
- Kurreeman FAS, Padyukov L, Marques RB, Schrodi SJ, Seddighzadeh M, Stoeken-Rijsbergen G, van der Helm-van Mil AHM, Allaart CF, Verduyn W, Houwing-Duistermaat J, Alfredsson L, Begovich AB, Klareskog L, Huizinga TWJ & Toes REM (2007), A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis, PLoS Medicine 4(9).
- van der Helm-van Mil AHM, Huizinga TWJ, de Vries RRP & Toes REM (2007), Emerging patterns of risk factor make-up enable subclassification of rheumatoid arthritis, Arthritis and Rheumatism 56(6).
- van der Straaten RJHM, Wessels JAM, de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Allaart CF, Tiller M, Huizinga TWJ & Guchelaar HJ (2007), Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in metho trexate-treated rheumatoid arthritis patients, Pharmacogenomics 8(2).
- van Duivenvoorde LM, Han WGH, Bakker AM, Louis-Plence P, Charbonnier LM, Apparailly F, van der Voort EIH, Jorgensen C, Huizinga TWJ & Toes REM (2007), Immunomodulatory dendritic cells inhibit Th1 responses and arthritis via different mechanisms, Journal of Immunology 179(3).
- Feitsma AL, Worthington J, Mil AHMVDHV, Plant D, Thomson W, Ursum J, van Schaardenburg D, van der Horst-Bruinsma IE, van Rood IJ, Huizinga TWJ, Toes REM & de Vries RRP (2007), Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development, Proceedings of the National Academy of Sciences 104(50).
- Huizinga T, van der Helm-van Mil A, Verpoort KN, Kurreeman F, Thabet M, Schonkeren J & Toes REM (2007), Progress in understanding the pathogenesis of RA by identifying genetic risk factors, Inflammation Research 56.
- Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, van der Helm-van Mil AHM, Toes REM, Huizinga TW, Klareskog L & Alfredsson L (2007), Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis, American Journal of Human Genetics 80(5).
- Wang J, Scherer HU, van Dongen H & Huizinga TW (2007), Suppressor activity among CD4+CD25++ T cells discriminated by membrane-bound TNF, Annals of the Rheumatic Diseases 66.
- van Oosterhout M, Bajema IM, Levarht NWN, Toes REM, Huizinga TJ & van Laar JM (2007), Synovial differences between anti-CCP positive, Annals of the Rheumatic Diseases 66.
- van der Helm - van Mil AHM, Verpoort KN, Pruijn GJM, de Vries RRP, Allaart C, Huizinga TWJ & Toes REM (2007), The HLA-DBR1 shared epitope allieles influence both the magnitude and specificity of the ACPA-response in ACPA-positive rheumatoid arthritis patients, Annals of the Rheumatic Diseases 66.
- van der Helm-van Mil AHM, le Cessie S, van Dongen H, Breedveld FC, Toes REM & Huizinga TWJ (2007), A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis - How to guide individual treatment decisions, Arthritis and Rheumatism 56(2).
- van der Helm-van Mil AHM, Verpoort KN, le Cessie S, Huizinga TWJ, de Vries RRP & Toes REM (2007), The HLA-DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide, Arthritis and Rheumatism 56(2).
- Pincus T, Huizinga TWJ & Yazici Y (2007), N-of-1 trial of low-dose methotrexate and/or prednisolone in lieu of anti-CCP, MRI, or ultrasound, as first option in suspected rheumatoid arthritis?, Journal of Rheumatology 34(2).
- de Boer IG, Lard LR, van den Berg MH, Mertens BJA, Huizinga TWJ & Vlieland TV (2007), Information needs regarding rheumatology health care services: a survey among patients with rheumatoid arthritis (RA), Annals of the Rheumatic Diseases 66.
- Kooloos WM, de Jong DJ, Huizinga TWJ & Guchelaar HJ (2007), Potential role of pharmacogenetics in anti-TNF treatment of rheumatoid arthritis and Crohn's disease, Drug Discovery Today 12(3-4).
- Feitsma AL, Worthington J, van der Helm-van Mil AHM, Plant D, van der Horst-Bruinsma IE, Huizinga TWJ, Toes REM & de Vries RRP (2007), Protective effect on rheumatoid arthritis of non-inherited maternal HLA-DR antigens, Annals of the Rheumatic Diseases 66.
- Steenvoorden MMC, Bank RA, Ronday HK, Toes REM, Huizinga TWJ & DeGroot J (2007), Fibroblast-like synoviocyte-chondrocyte interaction in cartilage degradation, Clinical and Experimental Rheumatology 25(2).
- Monraats, P.S.; Kurreeman, F.A.S.; Pons, D.; Sewgobind, V.D.K.D.; Vries, F.R. de; Zwinderman, A.H.; Maat, M.P.M. de; Doevendans, P.A.; Winter, R.J. de; Tio, R.A.; Waltenberger, J.; Huizinga, T.W.J.; Eefting, D.; Quax, P.H.A.; Frants, R.R.; Laarse, A. van der; Wall, E.E. van der & Jukema, J.W. (2007), Interleukin 10: a new risk marker for the development of restenosis after percutaneous coronary intervention, Genes and Immunity 8(1).
- de Poorter JJ, Lipinski KS, Nelissen RGHH, Huizinga TWJ & Hoeben RC (2007), Optimization of short-term transgene expression by sodium butyrate and ubiquitous chromatin opening elements (UCOEs), Journal of Gene Medicine 9(8).
- Bessis N, Lemeiter D, Laroche L, Fournier C, Huizinga T, Brok H, 't Hart B & Boissier MC (2007), Engraftment of cutaneous fibroblasts within synovial membrane in a nonhuman primate: Short-term results.
- Swen JJ, Huizinga TW, Gelderblom H, de Vries EGE, Assendelft WJJ, Kirchheiner J & Guchelaar HJ (2007), Translating pharmacogenomics: Challenges on the road to the clinic, PLoS Medicine 4(8).
- Teng, Y.; Hashemi, M.; Levarht, N.; Bajema, I.; Toes, R.; Huizinga, T. & Laar, J. van (2007), Depleting effects of anti-CD20 monoclonal antibodies in blood, bone marrow and synovium of patients with refractory rheumatoid arhtritis, Annals of the Rheumatic Diseases 66.
- Goekoop RJ, Gussekloo J, Dirkse V, Kroon HMJA, Huizinga TWJ, Westendorp RGJ & Kloppenburg M (2007), Ten percent of individuals do not develop osteoarthritis at very old age, Annals of the Rheumatic Diseases 66.
- Wang J, van Dongen H, Scherer HU, Huizinga TWJ & Toes REM (2007), Suppressor activity among CD4+CD25++ T cells is discriminated by membrane-bound TNF, Annals of the Rheumatic Diseases 66.
- van der Helm-van Mil AHM, Verpoort KN, Pruijn GJM, de Vries RRP, Allaart C, Huizinga TWJ & Toes REM (2007), The HLA-DBR1 shared epitope alleles influence both the magnitude and specificity of the ACPA-response in ACPA-positive rheumatoid arthritis patients, Annals of the Rheumatic Diseases 66.
- Thabet MM, Wesoly J, Slagboom PE, Toes REM & Huizinga TWJ (2007), FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians, Annals of the Rheumatic Diseases 66(6).
- Steup-Beekman GM, Steens SCA, van Buchem MA & Huizinga TWJ (2007), Anti-NMDA receptor autoantibodies in patients with systemic lupus erythematosus and their first-degree relatives, Lupus 16(5).
- Linn-Rasker SP, van der Helm-van Mil AHM, Breedveld FC & Huizinga TWJ (2007), Arthritis of the large joints - in particular, the knee - at first presentation is predictive for a high level of radiological destruction of the small joints in rheumatoid arthritis, Annals of the Rheumatic Diseases 66(5).
- Rood MJ, Lavrijsen SPM & Huizinga TWJ (2007), Acitretin-related ossification, Journal of Rheumatology 34(4).
- Feitsma AL, Toes REM, Begovich AB, Chokkalingam AP, de Vries RRP, Huizinga TWJ & van der Helm-van Mil AHM (2007), Risk of progression from undifferentiated arthritis to rheumatoid arthritis: the effect of the PTPN22 1858T-allele in anti-citrullinated peptide antibody positive patients, Rheumatology 46(7).
- Verpoort KN, Cheung K, Ioan-Facsinay A, Mil AVHV, de Vries R, Breedveld FC, Huizinga TWJ, Pruijn GJM & Toes REM (2007), Fine-specificity of the antibodies against citrullinated protein response is influenced by shared epitope alleles, Arthritis Research and Therapy 9.
- Kurreeman FAS, Verpoort KN, Ioan-Facsinay A, Schonkeren JJM, Uh H, Slagboom E, Westendorp R, Toes REM & Huizinga TWJ (2007), The association between IL10 and joint destruction in RA can be attributed to enhanced autoantibody responses, Annals of the Rheumatic Diseases 66.
- Verpoort KN, Cheung K, Ioan-Facsinay A, van der Helm-van Mil AHM, de Vries-Bouwstra JK, Allaart CF, Drijfhout JW, de Vries RRP, Breedveld FC, Huizinga TWJ, Pruijn GJM & Toes REM (2007), Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles, Arthritis and Rheumatism 56(12).
- Teng, Y.K.O.; Levarht, E.W.N.; Hashemi, M.; Bajema, I.M.; Toes, R.E.A.; Huizinga, T.W.J. & Laar, J.M. van (2007), Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment, Arthritis and Rheumatism 56(12).
- Steenvoorden MMC, Toes REM, Ronday HK, Huizinga TWJ & DeGroot J (2007), RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro, Clinical and Experimental Rheumatology 25(5).
- Sigurdsson S, Padyukov L, Kurreeman FAS, Liljedahl U, Wiman AC, Alfredsson L, Toes R, Ronnelid J, Klareskog L, Huizinga TWJ, Alm G, Syvanen AC & Ronnblom L (2007), Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis, Arthritis and Rheumatism 56(7).
- van der Bijl AE, Emmer BJ, Breedveld FC, Middelkoop HAM, Jurgens CK, van Buchem MA, Huizinga TWJ & van der Grond J (2007), Advanced magnetic resonance imaging of the brain in patients treated with TNF-alpha blocking agents, Clinical and Experimental Rheumatology 25(2).
- van Dongen H, van Aken J, Lard LR, Visser K, Ronday HK, Hulsmans HMJ, Speyer I, Westedt ML, Peeters AJ, Allaart CF, Toes REM, Breedveld FC & Huizinga TWJ (2007), Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis - A double-blind, randomized, placebo-controlled trial, Arthritis and Rheumatism 56(5).
- van der Helm-van Mil AH, Kurreeman FA, Toes RE & Huizinga TW (2007), Association of tumor necrosis factor alpha polymorphism and radiographic progression in rheumatoid arthritis: comment on the article by Khanna et al, Arthritis and Rheumatism 56(3).
- Kurreeman FAS, Verpoort KN, Ioan-Facsinay A, Schonkeren JJM, Uh HW, Slagboom E, Westendorp RG, Toes REM & Huizinga TWJ (2007), The association between IL10 and joint destruction in RA can be attributed to enhanced autoantibody responses, Annals of the Rheumatic Diseases 66.
- Wessels JAM, Huizinga TWJ, Guchelaar HJ & de Jonge R (2007), Effect of the 34C > T variant in the AMPD1 gene on the clinical response to methotrexate in patients with rheumatoid arthritis: comment on the article by Wessels et al - Reply, Arthritis and Rheumatism 56(2).
- Wang J, Ioan-Facsinay A, Van der Voort EIH, Huizinga TWJ & Toes REM (2007), Transient expression of FOXP3 in human activated nonregulatory CD4(+) T cells, European Journal of Immunology 37(1).
- Wang J, Ioan-Facsinay A, Scherer HU, van der Voort EIH, Huizinga TWJ & Toes REM (2007), Transient expression of FOXP3 in human activated nonregulatory CD4+T cells, Annals of the Rheumatic Diseases 66.
- van Duivenvoorde L, Han W, Bakker A, Louis-Plence P, Charbonnier LM, Apparailly F, van der Voort E, Jorgenson C, Huizinga T & Toes R (2007), Protection against collagen-induced arthritis with differentially modulated dendritic cells, Annals of the Rheumatic Diseases 66.
- Teng YKO, Verburg RJ, Verpoort KN, Diepenhorst GMP, Bajema IM, Tol MJD, Jol-van der zijde ECM, Toes REM, Huizinga TW & van Laar JM (2007), Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study, Arthritis Research and Therapy 9(5).
- Wessels JAM, van der Kooij SM, le Cessie S, Kievit W, Barerra P, Allaart CF, Huizinga TWJ & Guchelaar HJ (2007), A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis, Arthritis and Rheumatism 56(6).
- Timmer TCG, Baltus B, Vondenhoff M, Huizinga TWJ, Tak PP, Verweij CL, Mebius RE & Kraan TCTMV (2007), Identification of the interleukin-7 signalling pathway in rheumatoid arthritis synovial tissues with lymphoid neogenesis, Annals of the Rheumatic Diseases 66.
- Verpoort KN, Voort EAMP, Mil AHMV, Zijde CMJ, van Tol MJD, Drijfhout JW, Breedveld FC, de Vries RRP, Huizinga TWJ & Toes REM (2007), Association of smoking with the constitution of the anti-cyclic citrullinated peptide response in the absence of HLA-DRB1 shared epitope alleles, Arthritis and Rheumatism 56(9).
- Wang J, Scherer HU, Van Dongen H, Huizinga TW & Toes REM (2007), Membrane-bound TNF discriminates suppressor activity among CD4+CD25++ T cells, Zeitschrift f�r Rheumatologie 66.
- de Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Wesoly J, Hulsmans HJ, de Craen AJM, Breedveld FC, Dijkmans BAC, Allaart CF & Huizinga TWJ (2007), Ex vivo interleukin 1 receptor antagonist production on lipopolysaccharide stimulation is associated with rheumatoid arthritis and with joint damage, Annals of the Rheumatic Diseases 66(8).
- Wesoly J, Hu X, Thabet MM, Chang M, Uh H, Allaart CF, Toes REM, Houwing-Duistermaat JJ, Begovich AB & Huizinga TWJ (2007), The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population, Rheumatology 46(4).
- van der Helm-van Mil AHM, Verpoort KN, Huizinga TWJ, de Vries RRP & Toes REM (2007), Refinement of the contribution of smoking to the ACPA response, Annals of the Rheumatic Diseases 66.
- Botha-Scheepers S, Watt I, Slagboom E, Craen AJM, Meulenbelt I, Rosendaal F, Breedveld FC, Huizinga TWJ & Kloppenburg M (2007), Innate production of tumor necrosis factor-alpha and interleukin-10 is associated with radiological progression of knee osteoarthritis, Annals of the Rheumatic Diseases 66.
- Maes P, Clement J, Groeneveld PHP, Colson P, Huizinga TWJ & Van Ranst M (2006), Tumor necrosis factor-alpha genetic predisposing factors can influence clinical severity in nephropathia epidemica, Viral Immunology 19(3).
- Emmer BJ, Steens SCA, Steup-Beekman GM, van der Grond J, Admiraal-Behloul F, Olofsen H, Bosma GPT, Ouwendijk WJN, Huizinga TWJ & van Buchem MA (2006), Detection of change in CNS involvement in neuropsychiatric SLE: A magnetization transfer study, Journal of Magnetic Resonance Imaging 24(4).
- van Dunne FM, de Craen AJM, Helmerhorst FM, Huizinga TWJ & Westendorp RGJ (2006), Interleukin-10 promoter polymorphisms in male and female fertility and fecundity, Genes and Immunity 7(8).
- van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Huizinga TWJ, Toes REM & de Vries RRP (2006), The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis, Arthritis and Rheumatism 54(4).
- Schoe A, van der Laan-Baalbergen NE, Huizinga TWJ, Breedveld FC & van Laar JM (2006), Pulmonary fibrosis in a patient with rheumatoid arthritis treated with adalimumab, Arthritis and Rheumatism 55(1).
- Wessels JAM, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJSM, van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar HJ (2006), Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes, Arthritis and Rheumatism 54(4).
- de Vries RRP, Huizinga TWJ & Toes REM (2006), HLA and RA revisited: Citrullinated food for the SE hypothesis, the DR6 effect, and NIMA, Human Immunology 67(6).
- Tolboom TCA, Zhang YH, Henriquez NV, Nelissen RGHH, Toes REM, Noteborn MHM & Huizinga TWJ (2006), Fibroblast-like synoviocytes from patients with rheumatoid arthritis are more sensitive to apoptosis induced by the viral protein, apoptin, than fibroblast-like synoviocytes from trauma patients, Clinical and Experimental Rheumatology 24(2).
- Thabet MM & Huizinga TWJ (2006), Drug evaluation: Apratastat, a novel TACE/MMP inhibitor for rheumatoid arthritis, Current Opinion in Investigational Drugs 7(11).
- Steenvoorden MMC, Huizinga TWJ, Verzijl N, Bank RA, Ronday HK, Luning HAF, Lafeber FPJG, Toes REM & DeGroot J (2006), Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes, Arthritis and Rheumatism 54(1).
- de Vries-Bouwstra J, Le Cessie S, Allaart C, Breedveld F & Huizinga T (2006), Using predicted disease outcome to provide differentiated treatment of early rheumatoid arthritis, Journal of Rheumatology 33(9).
- Steup-Beekman GM, Gahrmann BMA, Steens SCA, van Buchem MA & Huizinga TWJ (2006), Seasonal variation of primary neuropsychiatric systemic lupus erythematosus, Journal of Rheumatology 33(9).
- Charbonnier LM, van Duivenvoorde LM, Apparailly F, Cantos C, Han WGH, Noel D, Duperray C, Huizinga TWJ, Toes REM, Jorgensen C & Louis-Plence P (2006), Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b(+) regulatory T cells, Journal of Immunology 177(6).
- de Jong JMH, Schuurhuis DH, Ioan-Facsinay A, Welling MM, Camps MGM, van der Voort EIH, Huizinga TWJ, Ossendorp F, Verbeek JS & Toes REM (2006), Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4(+) T cells upon immune-complex uptake in vivo, Immunology 119(4).
- Emmer BJ, van der Grond J, Steup-Beekman GM, Huizinga TWJ & van Buchem MA (2006), Selective involvement of the amygdala in systemic lupus erythematosus, PLoS Medicine 3(12).
- de Poorter JJ, Obermann WR, Huizinga TWJ & Nelissen RGHH (2006), Arthrography in loosened hip prostheses. Assessment of possibilities for intra-articular therapy, Joint Bone Spine 73(6).
- Linn-Rasker SP, van der Helm-van Mil AHM, van Gaalen FA, Kloppenburg M, de Vries RRP, le Cessie S, Breedveld FC, Toes REM & Huizinga TWJ (2006), Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles, Annals of the Rheumatic Diseases 65(3).
- Steenvoorden MMC, Tolboom TCA, van der Pluijm G, Lowik C, Visser CPJ, DeGroot J, Gittenberger-DeGroot AC, DeRuiter MC, Wisse BJ, Huizinga TWJ & Toes REM (2006), Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics, Arthritis Research and Therapy 8(6).
- Steens SC, Bosma GP, Steup-Beekman GM, le Cessie S, Huizinga TWJ & Van Buchem MA (2006), Association between microscopic brain damage as indicated by magnetization transfer imaging and anticardiolipin antibodies in neuropsychiatric lupus, Arthritis Research and Therapy 8(2).
- Steup-Beekman GM, Emmer BJ, Van der Grond J, Van Buchem MA & Huizinga TW (2006), Unravelling the pathogenetic mechanisms leading to human neuropsychiatric SLE, Annals of the Rheumatic Diseases 65.
- Verpoort KN, Jol-van der Zijde CM, Papendrecht-van der Voort EAM, Ioan-Facsinay A, Drijfhout JW, van Tol MJD, Breedveld FC, Huizinga TWJ & Toes REM (2006), Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response, Arthritis and Rheumatism 54(12).
- Wessels JAM, Huizinga TWJ & Guchelaar HJ (2006), Association of methotrexate effects and single-nucleotide polymorphisms in the folate pathway in rheumatoid arthritis: comment on the article by Wessels et al - Reply, Arthritis and Rheumatism 54(10).
- Steenvoorden MMC, van der Helm-van Mil AHM, Stoeken G, Bank RA, DeVries RRP, Huizinga TWJ, DeGroot J & Toes REM (2006), The RAGE G82S polymorphism is not associated with rheumatoid arthritis independently of HLA-DRB1*0401, Rheumatology 45(4).
- Steup-Beekman GM, Steens SC, Van Buchem MA & Huizinga TW (2006), Nmda receptor autoantibodies in patients with systemic lupus erythematosus and their first degree relatives, Annals of the Rheumatic Diseases 65.
- Steup-Beekman GM, Emmer BJ, Steens SC, Van der Grond J, Admiraal-Behloui F, Olofsen H, Bosma GP, Ouwendijk WJ, Van Buchem MA & Huizinga TW (2006), Detection of changes in CNS involvement in neuropsychiatric SLE with magnetization transfer imaging, Annals of the Rheumatic Diseases 65.
- van der Helm-van Mil AHM, Breedveld FC & Huizinga TWJ (2006), Aspects of early arthritis - Definition of disease states in early arthritis: Remission versus minimal disease activity, Arthritis Research and Therapy 8(4).
- van Winkelen P, van Denderen JS, Vossen CY, Huizinga TWJ & Dekker FW (2006), How evidence-based are advertisements in journals regarding the subspecialty of rheumatology?, Rheumatology 45(9).
- de Jong JMH, Schuurhuis DH, Ioan-Facsinay A, van der Voort EIH, Huizinga TWJ, Ossendorp F, Toes REM & Verbeek JS (2006), Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8(+) T cells in vivo, Molecular Immunology 43(13).
- Zhernakova A, Eerligh P, Barrera P, Weseloy JZ, Huizinga TWJ, Roep BO, Wijmenga C & Koeleman BPC (2006), CTLA4 is differently associated with autoimmune diseases in the Dutch population (vol 118, pg 58, 2005), Human Genetics 119(1-2).
- van Aken J, van Dongen H, le Cessie S, Allaart CF, Breedveld FC & Huizinga TWJ (2006), Comparison of long term outcome of patients with rheumatoid arthritis presenting with undifferentiated arthritis or with rheumatoid arthritis: an observational cohort study, Annals of the Rheumatic Diseases 65(1).
- Verpoort K, Van der Helm-Van Mil AHM, de Vries RRP, Huizinga TWJ & Toes REM (2006), The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-citrullinated protein antibodies and not for the development of rheumatoid arthritis, Annals of the Rheumatic Diseases 65: A39-A39.
- Van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Huizinga TWJ, Toes REM & De Vries RRP (2006), The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-CCP antibodies and are not an independent risk factor to develop rheumatoid arthritis, Annals of the Rheumatic Diseases 65: 74-74.
- Botha-Scheepers S, Watt I, Slagboom E, de Craen T, Meulenbelt I, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2006), Innate production of tumor necrosis factor-alpha and interleukin-10 upon lipopolysaccharide stimulation are associated with radiological progression of knee osteoarthritis., Arthritis and Rheumatism 54(9).
- De Vries-Bouwstra JK, Goekoop-Ruiterman YPM, Verpoort KN, Schreuder GMT, De Bois MHW, Mallee C, Toes REM, De Vries RRP, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Allaart CF (2006), The association of HLA class II antigens and anti-CCP antibodies with progression of joint damage is affected by early and targeted treatment of rheumatoid arthritis, Annals of the Rheumatic Diseases 65: 88-89.
- Verpoort, K.N.; Jol-van Der Zijde, C.M.; Papendrecht-van der Voort, E.A.M.; Ioan-Facsinay, A.; Drijfhout, J.W.; Tol, M.J.D. van; Breedveld, F.C.; Huizinga, T.W.J. & Toes, R.E.M. (2006), Isotypes of anti-citrullinated peptide antibodies (ACPA) in undifferentiated arthritis and rheumatoid arthritis suggest an ongoing immune response, Annals of the Rheumatic Diseases 65: 102-102.
- Huizinga T, Verpoort KN, Van der Helm-van Mil AH, Toes REM, Mckay J, Weiser S, Zhong J & Freimuth W (2006), Distinct genetic and environmental risk factors, distinct disease outcome and distinct responses to anti-B cell therapy (lymphostat-B) indicate that anti-CCP-positive RA is a distinct disease entity, Annals of the Rheumatic Diseases 65: 59-59.
- Wesoly J, Dillingh MR, De Vries RRP, Toes REM & Huizinga TWJ (2006), DEK gene and susceptibility to rheumatoid arthitis, Annals of the Rheumatic Diseases 65: A40-A40.
- Wessels JAM, Kooloos WM, de Jonge R, de Vries-Bouwstra JK, Allaart CF, Linssen A, Collee G, de Sonnaville P, Lindemans J, Huizinga TWJ & Guchelaar HJ (2006), Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis, Arthritis and Rheumatism 54(9).
- van Duivenvoorde LM, Bakker AM, van Mierlo GJD, Huizinga TWJ & Toes REM (2006), Protection against collagen induced arthritis with differentially modulated dendritic cells, Annals of the Rheumatic Diseases 65: A10-A10.
- de Poorter JJ, Toboom TCA, Rabelink MJWE, Pieterman E, Hoeben RC, Nelissen RGHH & Huizinga TWJ (2005), Towards gene therapy in prosthesis loosening: efficient killing of interface cells by gene-directed enzyme prodrug therapy with nitroreductase and the prodrug CB1954, Journal of Gene Medicine 7(11).
- van der Slot AJ, van Dura EA, de Wit EC, De Groot J, Huizinga TWJ, Bank RA & Zuurmond AM (2005), Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels, BBA - Molecular Basis of Disease 1741(1-2).
- Riyazi N, Kurreeman FAS, Huizinga TWJ, Dekker FW, Stoeken-Rijsbergen G & Kloppenburg M (2005), The role of interleukin 10 promoter polymorphisms in the susceptibility of distal interphalangeal osteoarthritis, Journal of Rheumatology 32(8).
- Kasperkovitz PV, Timmer TCG, Smeets TJ, Verbeet NL, Tak PP, van Baarsen LGM, Baltus B, Huizinga TWJ, Pieterman E, Fero M, Firestein GS, Kraan TCTMV & Verweij CL (2005), Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity - Evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis, Arthritis and Rheumatism 52(2).
- Riyazi N, Slagboom E, de Craen AJM, Meulenbelt I, Houwing-Duistermaat JJ, Kroon HM, van Schaardenburg D, Rosendaal FR, Breedveld FC, Huizinga TWJ & Kloppenburg M (2005), Association of the risk of osteoarthritis with high innate production of interleukin-1 beta and low innate production of interleukin-10 ex vivo, upon lipopolysaccharide stimulation, Arthritis and Rheumatism 52(5).
- Drynda A, Quax PHA, Neumann M, van der Laan WH, Pap G, Drynda S, Meinecke I, Kekow J, Neumann W, Huizinga TWJ, Naumann M, Konig W & Pap T (2005), Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts, Journal of Immunology 174(10).
- de Jong JMH, Schuurhuis DH, Ioan A, Van der Voort EIH, Huizinga TWJ, Ossendorp F, Verbeek JS & Toes REM (2005), Fc gamma R-mediated uptake and processing of antigen-immunoglobulin complexes by professional antigen presenting cells., Arthritis and Rheumatism 52(9).
- Hoffman IEA, Peene I, Cebecauer L, Isenberg D, Huizinga TWJ, Union A, Meheus L, De Bosschere K, Hulstaert F, Veys EM & De Keyser F (2005), Presence of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus, Annals of the Rheumatic Diseases 64(2).
- Wessels JAM, de Vries-Bouwstra JK, Heijmans BT, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar HJ (2005), Single nucleotide polymorphisms in genes coding for folate pathway enzymes are determinants for methotrexate efficacy in early rheumatoid arthritis, Arthritis and Rheumatism 52(9).
- van der Helm-van Mil AHM, Huizinga TWJ, Schreuder GMT, Breedveld FC, de Vries RRP & Toes REM (2005), An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility, Arthritis and Rheumatism 52(9).
- Steens SCA, Steup-Beekman GM, Bosma GPT, Admiraal-Behloul F, Ofsen H, Doornbos J, Huizinga TWJ & van Buchem MA (2005), The effect of corticosteroid medication on quantitative MR parameters of the brain, American Journal of Neuroradiology 26(10).
- Van Aken J, Van Dongen H, Le Cessie S, Allaart CF, Breedveld FC & Huizinga TJ (2005), Long term outcome of rheumatoid arthritis that presented with undifferentiated arthritis compared to rheumatoid arthritis at presentation - An observational cohort study, Annals of the Rheumatic Diseases 64.
- Verpoort KN, van Gaalen FA, van der Helm-van Mil AHM, Schreuder GMT, Breedveld FC, Huizinga TWJ, de Vries RRP & Toes REM (2005), Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis, Arthritis and Rheumatism 52(10).
- Wessels JAM, De Vries-Bouwstra JK, Heijmans BT, Goekoop-Ruiterman YPM, Allaart CF, Kerstens PJS, Van Zeben D, Breedveld FC, Dijkmans BAC, Huizinga TWJ & Guchelaar H (2005), Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single nucleotide polymorphisms in genes coding for folate pathway enzymes, Annals of the Rheumatic Diseases 64.
- van Gaalen FA, Visser H & Huizinga TWJ (2005), A comparison of the diagnostic accuracy and prognostic value of the first and second anti-cyclic citrullinated peptides (CCP1 and CCP2) autoantibody tests for rheumatoid arthritis, Annals of the Rheumatic Diseases 64(10).
- Tolboom TCA, Mil AHMVDV, Nelissen RGHH, Breedveld FC, Toes REM & Huizinga TWJ (2005), Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis, Arthritis and Rheumatism 52(7).
- van der Helm-van Mil AHM, Wesoly JZ & Huizinga TWJ (2005), Understanding the genetic contribution to rheumatoid arthritis, Current Opinion in Rheumatology 17(3).
- Zhernakova A, Eerligh P, Barrera P, Weseloy JZ, Huizinga TWJ, Roep BO, Wijmenga C & Koeleman BPC (2005), CTLA4 is differentially associated with autoimmune diseases in the Dutch population, Human Genetics 118(1).
- Flierman R, Witteveen H, Van Der Voort E, Huizinga T, De Vries R, Fibbe W, Toes R & Van Laar J (2005), Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and MHC-mismatched allogeneic bone marrow transplantation, Annals of the Rheumatic Diseases 64.
- Tchetverikov I, Lohmander LS, Verzijl N, Huizinga TWJ, Tekoppele JM, Hanemaaijer R & DeGroot J (2005), MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis, Annals of the Rheumatic Diseases 64(5).
- Morgan ME, van Bilsen JHM, Bakker AM, Heemskerk B, Schilham MW, Hartgers FC, Elferink BG, van der Zanden L, de Vries RRP, Huizinga TWJ, Ottenhoff THM & Toes REM (2005), Expression of FOXP3 mRNA is not confined to CD4(+)CD25(+) T regulatory cells in humans, Human Immunology 66(1).
- Wesoly J, Toes REM, Slagboom PE & Huizinga TWJ (2005), RUNX1 intronic SNP is not associated with rheumatoid arthritis susceptibility in Dutch Caucasians, Rheumatology 44(9).
- Huizinga TWJ, Amos CI, van der Helm-van Mil AHM, Chen W, van Gaalen FA, Jawaheer D, Schreuder GMT, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RRP, Gregersen PK, Toes REM & Criswell LA (2005), Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins, Arthritis and Rheumatism 52(11).
- Schippers EF, van't Veer C, van Voorden S, Martina CAE, Huizinga TWJ, le Cessie S & van Dissel JT (2005), IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin, Cytokine 29(5).
- van der Helm-van Mil AHM, Verpoort KN, Breedveld FC, Toes REM & Huizinga TWJ (2005), Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis, Arthritis Research and Therapy 7(5).
- van der Slot-Verhoeven AJ, van Dura EA, Attema J, Blauw B, DeGroot J, Huizinga TWJ, Zuurmond AM & Bank RA (2005), The type of collagen cross-link determines the reversibility of experimental skin fibrosis, BBA - Molecular Basis of Disease 1740(1).
- van Gaalen F, Ioan-Facsinay A, Huizinga TWJ & Toes REM (2005), The devil in the details: The emerging role of anticitrulline autoimmunity in rheumatoid arthritis, Journal of Immunology 175(9).
- Steeghs N, Huizinga TWJ & Dik H (2005), Bilateral hydropneumothoraces in a patient with pulmonary rheumatoid nodules during treatment with methotrexate, Annals of the Rheumatic Diseases 64(11).
- Wesoly J, van der Helm-van Mil AHM, Toes RE, Chokkalingam AP, Carlton VEH, Begovich AB & Huizinga TWJ (2005), Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort, Arthritis and Rheumatism 52(9).
- Flierman R, Witteveen HJ, van der Voort EIH, Huizinga TWJ, de Vries RRP, Fibbe WE, Toes REM & van Laar JM (2005), Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and major histocompatibility complex-mismatched allogeneic bone marrow transplantation, Blood 105(7).
- Seelen MA, van der Bijl EA, Trouw LA, Zuiverloon TCM, Munoz JR, Fallaux-van den Houten FC, Schlagwein N, Daha MR, Huizinga TWJ & Roos A (2005), A role for mannose-binding lectin dysfunction in generation of autoantibodies in systemic lupus erythematosus, Rheumatology 44(1).
- Verpoort KN, van Gaalen FA, Helm-Van Mil AHMVD, Schreuder GMT, de Vries RRP, Breedveld FC, Huizinga TWJ & Toes REM (2005), HLA DR3 is associated with anti-CCP negative rheumatoid arthritis, Annals of the Rheumatic Diseases 64: 120-120.
- van Gaalen FA, Kraan TCTMV, Nelissen RGHH, Huizinga TWJ & Verweij CL (2005), Altered composition of CD97 splice variants in rheumatoid synovial tissue, Arthritis Research and Therapy 7: S10-S10.
- Van Gaalen FA, Visser H & Huizinga TW (2005), A comparison of the diagnostic accuracy and prognostic relevance of the CCP1 and CCP2 autoantibody tests for rheumatoid arthritis, Annals of the Rheumatic Diseases 64: 171-171.
- van Oosterhout M, Levarht EWN, Sont JK, Huizinga TWJ, Toes REM & van Laar JM (2005), Clinical efficacy of infliximab plus methotrexate in DMARD naive and DMARD refractory rheumatoid arthritis is associated with decreased synovial expression of TNF alpha and IL18 but not CXCL12, Annals of the Rheumatic Diseases 64(4).
- Verpoort KN, van Gaalen FA, van der Helm-van Mil A, Schreuder GMT, Breedveld FC, Huizinga TWJ, de Vries RRP & Toes REM (2005), Hla-dr3 is associated with anti-ccp antibody negative rheumatoid arthritis., Arthritis and Rheumatism 52(9): S150-S150.
- van Bilsen JHM, van Dongen H, Lard LR, van der Voort EIH, Elferink DG, Bakker AM, Miltenburg AMM, Huizinga TWJ, de Vries RRP & Toes REM (2004), Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis, Proceedings of the National Academy of Sciences 101(49).
- Polderman MCA, le Cessie S, Huizinga TWJ & Pavel S (2004), Efficacy of UVA-1 cold light as an adjuvant therapy for systemic lupus erythematosus, Rheumatology 43(11).
- ten Cate R, Smiers FJ, Bredius RGM, Lankester AC, van Suijlekom-Smit LWA, Huizinga TW & Egeler RM (2004), Anti-CD20 monoclonal antibody (rituximab) for refractory autoimmune thrombocytopenia in a girl with systemic lupus erythematosus, Rheumatology 43(2).
- van Dunne FM, Lard LR, Rook D, Helmerhorst FM & Huizinga TWJ (2004), Miscarriage but not fecundity is associated with progression of joint destruction in rheumatoid arthritis, Annals of the Rheumatic Diseases 63(8).
- de Jong Z, Munneke M, Zwinderman AH, Kroon HM, Ronday KH, Lems WF, Dijkmans BAC, Breedveld FC, Vlieland TPMV, Hazes JMW & Huizinga TWJ (2004), Long term high intensity exercise and damage of small joints in rheumatoid arthritis, Annals of the Rheumatic Diseases 63(11).
- Flierman R, Witteveen H, van der Voort E, Huizinga T, de Vries R, Fibbe W, Toes R & van Laar J (2004), Effective treatment of collagen-induced arthritis with nonmyeloablative conditioning and MHC-mismatched allogeneic bone marrow transplantation., Arthritis and Rheumatism 50(9).
- van den Biggelaar AHJ, Huizinga TWJ, de Craen AJM, Gussekloo J, Heijmans BT, Frolich M & Westendorp RGJ (2004), Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study, Experimental Gerontology 39(9).
- Riyazi N, Huizinga TJ, de Craen AR, Meulenbelt I, Kroon HM, Rosendaal R, Breedveld FC, Slagboom E & Kloppenburg M (2004), Identification of three new genetically determined risk factors for osteoarthritis (OA): High levels of interleukin (IL)-1 beta and IL-receptor antagonist (IL-1Ra) and low IL-10 production, Annals of the Rheumatic Diseases 63.
- Bosma GPT, Steens SCA, Petropoulos H, Admiraal-Behloul F, van den Haak A, Doornbos J, Huizinga TWJ, Brooks WM, Harville A, Sibbitt WL & van Buchem MA (2004), Multisequence magnetic resonance imaging study of neuropsychiatric systemic lupus erythematosus, Arthritis and Rheumatism 50(10).
- Fransen J, Laan RFJM, van der Laar MAFJ, Huizinga TWJ & van Riel PLCM (2004), Influence of guideline adherence on outcome in a randomised controlled trial on the efficacy of methotrexate with folate supplementation in rheumatoid arthritis, Annals of the Rheumatic Diseases 63(10).
- Steens SCA, Admiraal-Behloul F, Bosma GPT, Steup-Beekman GM, Olofsen H, le Cessie S, Huizinga TWJ & van Buchem MA (2004), Selective gray matter damage in neuropsychiatric lupus - A magnetization transfer imaging study, Arthritis and Rheumatism 50(9).
- Hoffman IEA, Peene I, Meheus L, Huizinga TWJ, Cebecauer L, Isenberg D, De Bosschere K, Hulstaert F, Veys EM & De Keyser F (2004), Specific antinuclear antibodies are associated with clinical features in systemic lupus erythematosus, Annals of the Rheumatic Diseases 63(9).
- Vanderborght PR, Matos HJ, Salles AM, Vasconcellos SE, Silva VF, Huizinga TWJ, Ottenhoff THM, Sampaio EP, Sarno EN, Santos AR & Moraes MO (2004), Single nucleoticle polymorphisms (SNPs) at -238 and -308 positions in the TNF alpha promoter: Clinical and bacteriological evaluation in leprosy, International Journal of Leprosy and Other Mycobacterial Diseases 72(2).
- van Gaalen FA, van Aken J, Huizinga TWJ, Schreuder GMT, Breedveld FC, Zanelli E, van Venrooij WJ, Verweij CL, Toes REM & de Vries RRP (2004), Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis, Arthritis and Rheumatism 50(7).
- Flierman R, Morgan L, van Dulvenvoorde L, de Vries RRP, Fibbe WE, Huizinga TJW, Toes REM & van Laar JM (2004), Allogeneic bone marrow transplantation can suppress established and otherwise chronic collagen-induced arthritis after a nonmyeloablative conditioning regimen employing anti-CD40 ligand monoclonal antibody, Arthritis Research and Therapy 6.
- van Aken J, Lard LR, le Cessie S, Hazes JMW, Breedveld FC & Huizinga TWJ (2004), Radiological outcome after four years of early versus delayed treatment strategy in patients with recent onset rheumatoid arthritis, Annals of the Rheumatic Diseases 63(3).
- van Gaalen FA, Linn-Rasker SP, van Venrooij WJ, de Jong BA, Breedveld FC, Verweij CL, Toes REM & Huizinga TWJ (2004), Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis - A prospective cohort study, Arthritis and Rheumatism 50(3): 709-715.
- van Gaalen FA, Toes REM, Ditzel HJ, Schaller M, Breedveld FC, Verweij CL & Huizinga TWJ (2004), Association of autoantibodies to glucose-6-phosphate isomerase with extraarticular complications in rheumatoid arthritis, Arthritis and Rheumatism 50(2): 395-399.
- van Gaalen FA, van Aken J, Huizinga TW, Schreuder GM, Breedveld FC, Zanelli E, van Venrooij WJ, Verweij C, Toes RE & de Vries R (2004), Association between Hla class Ii genes and autoantibodies to cyclic citrullinated peptides (Ccp) affects severity of rheumatoid arthritis., Arthritis and Rheumatism 50(9): S359-S359.
- Meulenbelt I, Seymour AB, Nieuwland M, Huizinga TWJ, van Duijn CM & Slagboom PE (2004), Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip, Arthritis and Rheumatism 50(4).
- Moraes MO, Pacheco AG, Schonkeren JJM, Vanderborght PR, Nery JAC, Santos AR, Moraes ME, Moraes JR, Ottenhoff THM, Sampaio EP, Huizinga TWJ & Sarno EN (2004), Interleukin-10 promoter single-nucleotide polymorphisms as markers for disease susceptibility and disease severity in leprosy, Genes and Immunity 5(7).
- Kurreeman FAS, Schonkeren JJM, Heijmans BT, Toes REM & Huizinga TWJ (2004), Transcription of the IL10 gene reveals allele-specific regulation at the mRNA level, Human Molecular Genetics 13(16).
- de Groot CJM, Jansen MWJC, Bertina RM, Schonkeren JJM, Helmerhorst F & Huizinga TWJ (2004), Interleukin 10-2849AA genotype protects against pre-eclampsia, Genes and Immunity 5(4).
- van den Biggelaar AHJ, de Craen AJM, Gussekloo J, Huizinga TWJ, Heijmans BT, Frolich M, Kirkwood TBL & Westendorp RGJ (2004), Inflammation underlying cardiovascular mortality is a late consequence of evolutionary programming, FASEB Journal 18(6).
- Lard LR, Roep BO, Toes REM & Huizinga TWJ (2004), Enhanced concentrations of interleukin 16 are associated with joint destruction in patients with rheumatoid arthritis, Journal of Rheumatology 31(1).
- De Vries-Bouwstra JK, le Cessie S, Allaart CF, Breedveld FC & Huizinga TWJ (2003), Using predicted disease outcome to provide differentiated treatment of early rheumatoid arthritis., Arthritis and Rheumatism 48(9).
- Bosma GPT, Huizinga TWJ, Mooijaart SP & van Buchem MA (2003), Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus, American Journal of Neuroradiology 24(5).
- Steens SCA, Bosma GPT, ten Cate R, Doornbos J, Kros JM, Laan LAEM, Steup-Beekman GM, van Buchem MA & Huizinga TWJ (2003), A neuroimaging follow up study of a patient with juvenile central nervous system systemic lupus erythematosus, Annals of the Rheumatic Diseases 62(6).
- van der Pouw Kraan TCTM, van Gaalen F, Huizinga TWJ, Pieterman E, Breedveld FC & Verweij CL (2003), Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair, Genes and Immunity 4(3): 187-196.
- van Gaalen FA, Toes REM, Ditzel HJ, Schaller M, Verweij CL & Huizinga TWJ (2003), Autoantibodies to GPI are predominantly present in extra-articular complications of human rheumatoid arthritis, Arthritis Research and Therapy 5: S9-S9.
- Tolboom TCA, Medema JP, van Gaalen FA, Huizinga TJ & Toes REM (2003), Fibroblast-like synoviocytes from rheumatoid arthritis patients express less FLICE-inhibitory protein than fibroblast-like synoviocytes from trauma patients: comment on the article by Schedel et al, Arthritis and Rheumatism 48(3).
- Hoekstra M, van Ede AE, Haagsma CJ, van de Laar MAFJ, Huizinga TWJ, Kruijsen MWM & Laan RFJM (2003), Factors associated with toxicity, final dose, and efficacy of methotrexate in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 62(5).
- Lard LR, van Gaalen FA, Schonkeren JJM, Pieterman EJ, Stoeken G, Vos K, Nelissen RGHH, Westendorp RGJ, Hoeben RC, Breedveld FC, Toes REM & Huizinga TWJ (2003), Association of the-2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis, Arthritis and Rheumatism 48(7).
- van der Laan WH, Quax PHA, Seemayer CA, Huisman LGM, Pieterman EJ, Grimbergen JM, Verheijen JH, Breedveld FC, Gay RE, Gay S, Huizinga TWJ & Pap T (2003), Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3, Gene Therapy 10(3).
- van Aken J, van Bilsen JHM, Allaart CF, Huizinga TWJ & Breedveld FC (2003), The Leiden Early Arthritis Clinic, Clinical and Experimental Rheumatology 21(5).
- Boers M, Nurmohamed MT, Doelman CJA, Lard LR, Verhoeven AC, Voskuyl AE, Huizinga TWJ, van de Stadt RJ, Dijkmans BAC & van der Linden S (2003), Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis, Annals of the Rheumatic Diseases 62(9).
- Grootscholten C, Ligtenberg G, Derksen RHWM, Schreurs KMG, de Glas-Vos JW, Hagen EC, Bake AWLV, Huizinga TWJ, van den Hoogen FHJ, Bijl M, van Houwelingen JC, Snoek FJ & Berden JHM (2003), Health-related quality of life in patients with systemic lupus erythematosus: Development and validation of a lupus specific symptom checklist, Quality of Life Research 12(6).
- Wirtz PW, Huizinga TWJ, Stoeken DJ, Wintzen AR & Verschuuren JJ (2003), High innate production of interleukin-10 and tumor necrosis factor-alpha contributes to susceptibility for non-paraneoplastic Lambert-Eaton myasthenic syndrome, Journal of Neuroimmunology 140(1-2).
- van der Pol WL, Jansen MD, Sluiter WJ, van de Sluis B, Leppers-van de Straat FGJ, Kobayashi T, Westendorp RGJ, Huizinga TWJ & van de Winkel JGJ (2003), Evidence for non-random distribution of Fc gamma receptor genotype combinations, Immunogenetics 55(4).
- Moraes MO, Santos AR, Schonkeren JJM, Vanderborght PR, Ottenhoff THM, Moraes ME, Moraes JR, Sampaio EP, Sarno EN & Huizinga TWJ (2003), Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population, Immunogenetics 54(12).
- Riyazi N, Spee J, Huizinga TWJ, Schreuder GMT, de Vries RRP, Dekker FW & Kloppenburg M (2003), HLA class II is associated with distal interphalangeal osteoarthritis, Annals of the Rheumatic Diseases 62(3).
- Kraan TCTMV, van Gaalen FA, Kasperkovitz PV, Verbeet NL, Smeets TJM, Kraan MC, Fero M, Tak PP, Huizinga TWJ, Pieterman E, Breedveld FC, Alizadeh AA & Verweij CL (2003), Rheumatoid arthritis is a heterogeneous disease - Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues, Arthritis and Rheumatism 48(8): 2132-2145.
- van Gaalen FA, Linn-Rasker SP, van Venrooij WJ, de Jong BA, Breedveld FC, Verweij CL, Toes REM & Huizinga TWJ (2003), Autoantibodies predict progression to rheumatoid arthritis in undifferentiated arthritis: a prospective cohort study, Arthritis Research and Therapy 5: S9-S9.
- van Gaalen FA, Lard L, Schonkeren J, Pieterman E, Stoeken G, Vos K, Nelissen R, Westendorp R, Hoeben R, Breedveld FC, Toes R & Huizinga TWJ (2003), A polymorphism in the IL-10 promoter affects autoantibody production and subsequent joint destruction in rheumatoid arthritis, Arthritis Research and Therapy 5: S18-S19.
- Huizinga T, Schonkeren J, Kurreeman F, van Gaalen F, Westendorp R, Breedveld FC & Toes R (2003), Analysis of IL-10 gene variants in rheumatoid arthritis, Arthritis Research and Therapy 5: S25-S25.
- Jeurissen SER, Liauw L, Willems LNA & Huizinga TWJ (2003), Case Number 27: Jaw claudication in Takayasu's disease, Annals of the Rheumatic Diseases 62(10).
- de Jong BA, Huizinga TWJ, Zanelli E, Giphart MJ, Bollen ELEM, Uitdehaag BMJ, Polman CH & Westendorp RGJ (2002), Evidence for additional genetic risk indicators of relapse-onset MS within the HLA region, Neurology 59(4).
- Huizinga TWJ, Machold KP, Breedveld FC, Lipsky PE & Smolen JS (2002), Criteria for early rheumatoid arthritis - From Bayes' law revisited to new thoughts on pathogenesis, Arthritis and Rheumatism 46(5).
- Jong, B.A. de; Huizinga, T.W.J.; Bollen, E.L.E.M.; Uitdehaag, B.M.J.; Bosma, G.P.T.; Buchem, M.A. van; Remarque, E.J.; Burgmans, A.C.S.; Kalkers, N.F.; Polman, C.H. & Westendorp, R.G.J. (2002), Production of IL-1 beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis, Journal of Neuroimmunology 126(1-2).
- Kraan TCTV, van Gaalen FA, Alizadeh AA, Fero M, Huizinga TWJ, Pieterman E, Breedveld FC, Botstein D, Brown PO & Verweij CL (2002), Distinctive gene expression profiles in synovial tissue from rheumatoid arthritis patients by cDNA microarray analysis., Arthritis and Rheumatism 46(9): S266-S267.
- de Jong BA, Westendorp RGJ, Bakker AM & Huizinga TWJ (2002), Polymorphisms in or near tumour necrosis factor (TNF)-gene do not determine levels of endotoxin-induced TNF production, Genes and Immunity 3(1).
- Lard LR, Boers M, Verhoeven A, Vos K, Visser H, Hazes JMW, Zwinderman AH, Schreuder GMT, Breedveld FC, de Vries RRP, van der Linden S, Zanelli E & Huizinga TWJ (2002), Early and aggressive treatment of rheumatoid arthritis patients affects the association of HLA class II antigens with progression of joint damage, Arthritis and Rheumatism 46(4).
- Santos AR, Suffys PN, Vanderborght PR, Moraes MO, Vieira LMM, Cabello PH, Bakker AM, Matos HJ, Huizinga TWJ, Ottenhoff THM, Sampaio EP & Sarno EN (2002), Role of tumor necrosis factor-alpha and interleukin-10 promoter gene polymorphisms in leprosy, Journal of Infectious Diseases 186(11).
- Tolboom TCA, Pieterman E, van der Laan WH, Toes REM, Huidekoper AL, Nelissen RGHH, Breedveld FC & Huizinga TWJ (2002), Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10, Annals of the Rheumatic Diseases 61(11).
- de Craen AJM, Huizinga TWJ & Westendorp RGJ (2002), Multiple sclerosis and type 1 diabetes in Sardinia, Lancet 360(9341).
- Bosma GPT, Middelkoop HAM, Rood MJ, Bollen ELEM, Huizinga TWJ & van Buchem MA (2002), Association of global brain damage and clinical functioning in neuropsychiatric systemic lupus erythematosus, Arthritis and Rheumatism 46(10).
- de Jong BA, Westendorp RGJ, Eskdale J, Uitdehaag BMJ & Huizinga TWJ (2002), Frequency of functional interleukin-10 promoter polymorphism is different between relapse-onset and primary progressive multiple sclerosis, Human Immunology 63(4).
- Dehmeshki J, Van Buchem M, Bosma GPT, Huizinga TWJ & Tofts PS (2002), Systemic lupus erythematosus: Diagnostic application of magnetization transfer ratio histograms in patients with neuropsychiatric symptoms - Initial results, Radiology 222(3).
- Lard LR, Roep BO, Verburgh CA, Zwinderman AH & Huizinga TWJ (2002), Elevated IL-16 levels in patients with systemic lupus erythematosus are associated with disease severity but not with genetic susceptibility to lupus, Lupus 11(3).
- Huizinga TWJ, Linn-Rasker S, Lard LR & Westendorp RGJ (2002), Genetic drift as an explanation for the reduced incidence of rheumatoid arthritis, Arthritis and Rheumatism 46(11).
- van der Pol WL, Huizinga TWJ, Vidarsson G, van der Linden MW, Jansen MD, Keijsers V, de Straat FGJLV, Westerdaal NAC, de Winkel JGJV & Westendorp RGJ (2001), Relevance of Fc gamma receptor and interleukin-10 polymorphisms for meningococcal disease, Journal of Infectious Diseases 184(12).
- Westendorp RGJ, van Dunne GM, Kirkwood TBL, Helmerhorst FM & Huizinga TWJ (2001), Optimizing human fertility and survival, Nature Medicine 7(8).
- Lard LR, Huizinga TWJ, Hazes JMW & Vlieland TPMV (2001), Delayed referral of female patients with rheumatoid arthritis, Journal of Rheumatology 28(10).
- Huizinga TWJ, Steens SCA & van Buchem MA (2001), Imaging modalities in central nervous system systemic lupus erythematosus, Current Opinion in Rheumatology 13(5).
- van Ede AE, Laan RFJM, Rood MJ, Huizinga TWJ, van de Laar MAFJ, van Denderen CJ, Westgeest TAA, Romme TC, de Rooij DJRAM, Jacobs MJM, de Boo TM, van der Wilt GJ, Severens JL, Hartman M, Krabbe PFM, Dijkmans BAC, Breedveld FC & van de Putte LBA (2001), Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis - A forty-eight-week, multicenter, randomized, double-blind, placebo-controlled study, Arthritis and Rheumatism 44(7).
- Bayley JP, de Rooij H, van den Elsen PJ, Huizinga TWJ & Verweij CL (2001), Functional analysis of linker-scan mutants spanning the-376-308,-244, and-238 polymorphic sites of the TNF-alpha promoter, Cytokine 14(6).
- Gibson AW, Edberg JC, Wu JM, Westendorp RGJ, Huizinga TWJ & Kimberly RP (2001), Novel single nucleotide polymorphisms in the distal IL-10 promoter affect IL-10 production and enhance the risk of systemic lupus erythematosus, Journal of Immunology 166(6).
- van der Linden MW, Westendorp RGJ, Zidane M, Meheus L & Huizinga TWJ (2001), Autoantibodies within families of patients with systemic lupus erythematosus are not directed against the same nuclear antigens, Journal of Rheumatology 28(2).
- Goossens PH, Vogels R, Pieterman E, Havenga MJE, Bout A, Breedveld FC, Valerio D & Huizinga TWJ (2001), The influence of synovial fluid on adenovirus-mediated gene transfer to the synovial tissue, Arthritis and Rheumatism 44(1).
- Polderman MCA, Huizinga TWJ, Le Cessie S & Pavel S (2001), UVA-1 cold light treatment of SLE: a double blind, placebo controlled crossover trial, Annals of the Rheumatic Diseases 60(2).
- van Ede AE, Laan RFJM, Blom HJ, Huizinga TWJ, Haagsma CJ, Giesendorf BAJ, de Boo TM & van de Putte LBA (2001), The C677T mutation in the methylenetetrahydrofolate reductase gene - A genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients, Arthritis and Rheumatism 44(11).
- van der Linden MW, van der Slik AR, Zanelli E, Giphart MJ, Pieterman E, Schreuder GMT, Westendorp RGJ & Huizinga TWJ (2001), Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus, Genes and Immunity 2(7).
- Huizinga TWJ & Breedveld FC (2001), What will treatment of autoimmune diseases entail in 2010?, Springer Seminars in Immunopathology 23(1-2).
- Bruijn JA, Verburgh CA & Huizinga TWJ (2001), Classifying lupus nephritis: A 32-year-old woman with systemic lupus erythematosus and nephritic syndrome, American Journal of Kidney Diseases 37(3).
- Rood MJ, Haverman JF, van Duinen SG, Breedveld FC, Verschuuren JJGM & Huizinga TWJ (2001), CNS involvement in systemic lupus erythematosus: a case with remarkable histopathological findings, Annals of the Rheumatic Diseases 60(3).
- van der Linden MW, van Lopik T, Aarden LA, Westendorp RGJ & Huizinga TWJ (2001), Soluble CD95 concentrations are increased in patients with severe systemic lupus erythematosus, but not in their first degree relatives, Annals of the Rheumatic Diseases 60(3).
- de Jong BA, Schrijver HM, Huizinga TWJ, Bollen ELEM, Polman CH, Uitdehaag BMJ, Kersbergen MC, Sturk A & Westendorp RGJ (2000), Innate production of interleukin-10 and tumor necrosis factor affects the risk of multiple sclerosis, Annals of Neurology 48(4).
- Goossens PH, Heemskerk B, van Tongeren J, Zwinderman AH, Vlieland TPMV & Huizinga TWJ (2000), Reliability and sensitivity to change of various measures of hand function in relation to treatment of synovitis of the metacarpophalangeal joint in rheumatoid arthritis.
- Bosma GPT, Rood MJ, Zwinderman AH, Huizinga TWJ & Van Buchem MA (2000), Evidence of central nervous system damage in patients with neuropsychiatric systemic lupus erythematosus, demonstrated by magnetization transfer imaging.
- Goossens PH, Schouten GJ, Heemskerk B, 't Hart BA, Bout A, Kluin PM, Breedveld FC, Valerio D & Huizinga TWJ (2000), The effect of promoter strength in adenoviral vectors in hyperplastic synovium, Clinical and Experimental Rheumatology 18(5).
- Bosma GPT, Rood MJ, Huizinga TWJ, de Jong BA, Bollen ELEM & van Buchem MA (2000), Detection of cerebral involvement in patients with active neuropsychiatric systemic lupus erythematosus by the use of volumetric magnetization transfer imaging, Arthritis and Rheumatism 43(11).
- Huinink DT, Veltman GAM, Huizinga TWJ, Roelfsema F & Keizer HJ (2000), Diabetes insipidus in metastatic cancer: Two case reports with review of the literature, Annals of Oncology 11(7).
- van der Linden MW, Westendorp RGJ, Sturk A, Bergman W & Huizinga TWJ (2000), High interleukin-10 production in first-degree relatives of patients with generalized but not cutaneous lupus erythematosus.
- Rood MJ, Verschuuren JJGM, van Duinen SG, Maat-Schieman ML, Hegeman-Kleinn IM, van Buchem MA, Breedveld FC & Huizinga TWJ (2000), CNS involvement in primary Sjogren's syndrome: a case with a clue for the pathogenesis.
- Huizinga TWJ, Keijsers V, Yanni G, Hall M, Ramage W, Lanchbury J, Pitzalis C, Drossaers-Bakker WK, Westendorp RGJ, Breedveld FC, Panayi G & Verweij CL (2000), Are differences in interleukin 10 production associated with joint damage?, Rheumatology 39(11).
- Rood MJ, Borggreve SE & Huizinga TWJ (2000), Sensitivity to change of the MOS SF-36 quality of life assessment questionnaire in patients with systemic lupus erythematosus taking immunosuppressive therapy.
- Rood MJ, Van Krugten MV, Zanelli E, Van der Linden MW, Keijsers V, Schreuder GMT, Verduyn W, Westendorp RGJ, De Vries RRP, Breedveld FC, Verweij CL & Huizinga TWJ (2000), TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus.
- van Krugten MV, Huizinga TWJ, Kaijzel EL, Zanelli E, Drossaers-Bakker KW, van de Linde P, Hazes JMW, Zwinderman AH, Breedveld FC & Verweij CL (1999), Association of the TNF+489 polymorphism with susceptibility and radiographic damage in rheumatoid arthritis.
- Huizinga T.W.J., Rood M.J., Buchem M.A. van & Bollen E.L.E.M. (1997), De klinische presentatievormen, diagnostiek en therapie van neuropsychiatrische SLE. In: , Bindweefselziekten. Leiden: Boerhaave Commissie voor Postacademisch onderwijs in de Gene. 99-111.
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