Sebastian Geibel
Universitair hoofddocent
- Naam
- Dr. S.R.J. Geibel
- Telefoon
- +31 71 527 4544
- s.r.j.geibel@lic.leidenuniv.nl
- ORCID iD
- 0000-0003-0068-680X
Meer informatie is beschikbaar op de Engelse profielpagina.
Universitair hoofddocent
- Wiskunde en Natuurwetenschappen
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Biophysical Structural Chemistry
- Famelis N., Geibel S.R.J. & Tol D.J.C. van (2023), Mycobacterial type VII secretion systems, Biological Chemistry 404(7): 691-702.
- Geibel S.R.J. (2022), Typ-VII-Sekretionssysteme: Ziele gegen Tuberkulose, BioSpektrum 28: 128-131.
- Banchenko S., Weise C., Lanka E., Saenger W. & Geibel S.R.J. (2021), Helix bundle domain of primase RepB' is required for Dinucleotide formation and extension, ACS Omega 6(43): 28903-28911.
- Rivera-Calzada A., Famelis N., Llorca O. & Geibel S. (2021), Type VII secretion systems: structure, functions and transport models, Nature Reviews Microbiology 19(9): 567-584.
- Mietrach N., Damian-Aparicio D., Mielich-Suss B., Lopez D. & Geibel S. (2020), Substrate Interaction with the EssC Coupling Protein of the Type VIIb Secretion System, Journal of Bacteriology 202(7): .
- Mietrach N., Schlosser A. & Geibel S. (2019), An extracellular domain of the EsaA membrane component of the type VIIb secretion system: expression, purification and crystallization, Acta Crystallographica Section F: Structural Biology Communications 75: 725-730.
- Famelis N., Rivera-Calzada A., Degliesposti G., Wingender M., Mietrach N., Skehel J.M., Fernandez-Leiro R., Bottcher B., Schlosser A., Llorca O. & Geibel S. (2019), Architecture of the mycobacterial type VII secretion system, Nature 576(7786): 321-+.
- Mielich-Suss B., Wagner R.M., Mietrach N., Hertlein T., Marincola G., Ohlsen K., Geibel S. & Lopez D. (2017), Flotillin scaffold activity contributes to type VII secretion system assembly in Staphylococcus aureus, PLoS Pathogens 13(11): .
- Garcia-Fernandez E., Koch G., Wagner R.M., Fekete A., Stengel S.T., Schneider J., Mielich-Suss B., Geibel S., Markert S.M., Stigloher C. & Lopez D. (2017), Membrane Microdomain Disassembly Inhibits MRSA Antibiotic Resistance, Cell 171(6): 1354-+.
- Papaioannou D., Geibel S., Kunze M.B.A., Kay C.W.M. & Waksman G. (2016), Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide, Protein Science 25(3): 627-637.
- Farabella I., Pham T., Henderson N.S., Geibel S., Phan G., Thanassi D.G., Delcour A.H., Waksman G. & Topf M. (2014), Allosteric Signalling in the Outer Membrane Translocation Domain of PapC Usher, eLife 3: e03532.
- Lillington J., Geibel S. & Waksman G. (2014), Biogenesis and adhesion of type 1 and P pili, Biochimica et Biophysica Acta (BBA) - General Subjects 1840(9): 2783-2793.
- Geibel S. & Waksman G. (2014), The molecular dissection of the chaperone-usher pathway, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843(8): 1559-1567.
- Geibel S., Procko E., Hultgren S.J., Baker D. & Waksman G. (2013), Structural and energetic basis of folded-protein transport by the FimD usher, Nature 496(7444): 243-+.
- Rego A.T., Johnson J.G., Geibel S., Enguita F.J., Clegg S. & Waksman G. (2012), Crystal structure of the MrkD(1P) receptor binding domain of Klebsiella pneumoniae and identification of the human collagen V binding interface, Molecular Microbiology 86(4): 882-893.
- Geibel S. & Waksman G. (2011), Crystallography and Electron Microscopy of Chaperone/Usher Pilus Systems. In: Linke D. & Goldman A. (red.), Bacterial Adhesion: Chemistry, Biology and Physics. Advances in Experimental Medicine and Biology nr. 715. Dordrecht: Springer. 159-174.
- Phan G., Remaut H., Wang T., Allen W.J., Pirker K.F., Lebedev A., Henderson N.S., Geibel S., Volkan E., Yan J., Kunze M.B.A., Pinkner J.S., Ford B., Kay C.W.M., Li H.L., Hultgren S.J., Thanassi D.G. & Waksman G. (2011), Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate, Nature 474(7349): 49-U71.
- Geibel S., Banchenko S., Engel M., Lanka E. & Saenger W. (2009), Structure and function of primase RepB ' encoded by broad-host-range plasmid RSF1010 that replicates exclusively in leading-strand mode, Proceedings of the National Academy of Sciences 106(19): 7810-7815.
- Barany-Wallje E., Keller S., Serowy S., Geibel S., Pohl P., Bienert M. & Dathe M. (2005), A critical reassessment of penetratin translocation across lipid membranes, Biophysical Journal 89(4): 2513-2521.