Olivier Béquignon
Promovendus/gast
- Naam
- O.J.M. Béquignon
- Telefoon
- +31 71 527 2727
- o.j.m.bequignon@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0002-7554-9220
Meer informatie is beschikbaar op de Engelstalige profielpagina
Promovendus/gast
- Wiskunde en Natuurwetenschappen
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Maagdenberg H.W. van den, Šícho Martin A.D.A., Luukkonen S., Schoenmaker L., Jespers M., Béquignon O.J.M., Gorostiola González M.G., Broek R.L. van den, Bernatavicius R., Hasselt J.G.C. van, Graaf P.H. van der & Westen G.J.P. van (2024), QSPRpred: a flexible open-source quantitative structure-property relationship modelling tool, Journal of Cheminformatics 16: 128.
- den Hollander Lisa S. Zweemer Annelien J.M. Béquignon Olivier J.M. Hammerl Dora M. Bleijs Bente T.M. Veenhuizen Margo Lantsheer Wernard J.F. Chau Bobby van Westen Gerard J.P. IJzerman Adriaan P. Heitman Laura H. (2024), CC chemokine receptor 2 is allosterically modulated by sodium ions and amiloride derivatives through a distinct sodium ion binding site, Biochemical Pharmacology 229: 116464.
- Béquignon O.J.M., Gómez-Tamayo J.C., Lenselink E.B., Wink S., Hiemstra S.W., Lam C.C., Gadaleta D., Roncaglioni A., Norinder U., Water B. van de, Pastor M. & Westen G.J.P. van (2023), Collaborative SAR modeling and prospective in vitro validation of oxidative stress activation in human HepG2 cells, Journal of Chemical Information and Modeling 63(17): 5433-5445.
- Béquignon O.J.M., Bongers B.J., Jespers W., IJzerman A.P., Water B. van de & Westen G.J.P. van (2023), Papyrus: a large-scale curated dataset aimed at bioactivity predictions, Journal of Cheminformatics 15(1): 3.
- Hollander L.S. den, Béquignon O.J.M., Wang X., Wezel K. van, Broekhuis J.D., Gorostiola Gonzalez M., Visser K.E. de, IJzerman A.P., Westen G.J.P. van & Heitman L.H. (2023), Corrigendum to "Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism" [Biochem. Pharmacol. 208 (2023) 115399], Biochemical Pharmacology 209: 115540 (115450).
- Schoenmaker L., Béquignon O.J.M., Jespers W. & Westen G.J.P. van (2023), UnCorrupt SMILES: a novel approach to de novo design, Journal of Cheminformatics 15(1): 22.
- Sicho M., Luukkonena S., Maagdenberg H.W. van den, Schoenmaker L., Bequignon O.J.M. & Westen G.J.P. van (2023), DrugEx: deep learning models and tools for exploration of drug-like chemical space. [working paper].
- Liu Q., Stel W. van der, Noord V.E. van der, Leegwater H., Coban B., Elbertse K., Pruijs J.T.M., Béquignon O.J.M., Westen G.J.P. van, Dévédec S.E. le & Danen E.H.J. (2022), Hypoxia triggers TAZ phosphorylation in basal a triple negative breast cancer cells, International Journal of Molecular Sciences 23(17): 10119.
- Hollander L.S. den, Béquignon O.J.M., Wang X., Wezel K. van, Broekhuis J., Gorostiola González M., Visser K.E. de, IJzerman A.P., Westen G.J.P. van & Heitman L.H. (2022), Impact of cancer-associated mutations in CC chemokine receptor 2 on receptor function and antagonism, Biochemical Pharmacology 208: 115399.
- Béquignon O.J.M., Pawara G., Water B. van de, Cronin M.T.D. & Westen G.J.P. van (2021), Computational approaches for drug-induced liver injury (DILI) prediction: state of the art and challenges. In: Wolkenhauer O. (red.), Systems Medicine nr. 2: Elsevier. 308-329.
- Janssen A.P.A., Hengst J.M.A. van, Béquignon O.J.M., Deng H., Westen G.J.P. van & Stelt M. van der (2019), Structure Kinetics Relationships and Molecular Dynamics Show Crucial Role for Heterocycle Leaving Group in Irreversible Diacylglycerol Lipase Inhibitors, Journal of Medicinal Chemistry 62(17): 7910-7922.