Ned Buijs
Onderzoeker
- Naam
- Dr. N.P. Buijs Ph.D.
- Telefoon
- +31 71 527 4782
- n.p.buijs@biology.leidenuniv.nl
- ORCID iD
- 0000-0001-7613-4951
Voor meer informatie, zie de Engelse versie.
Onderzoeker
- Wiskunde en Natuurwetenschappen
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Machushynets V., Al Ayed K., Terlouw R., Du C., Buijs P., Willemse J., Elsayed S., Schill J., Trebosc V.: Pieren M., Alexander F.M., Cochrane S.A., Liles M.R., Medema M.H., Martin N.I. & Wezel G.P. van (2024), Discovery and derivatization of tridecaptin antibiotics with altered host specificity and enhanced bioactivity, ACS Chemical Biology 19(5): 1106-1115.
- Buijs N.P. (20 december 2023), Next generation bacitracin: reimagining a classic antibiotic (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Promotor(en) en copromotor(en): Martin N.I., Haren M.J. van.
- Wood T.M., Zeronian M.R., Buijs N.P., Bertheussen K., Abedian H.K., Johnson A.V., Pearce N.M., Lutz M., Kemmink J., Seirsma T., Hamoen L.W., Janssen B.J.C. & Martin N.I. (2022), Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures, Chemical Science 13(10): 2985-2991.
- Buijs N., Vlaming H.C., Haren M.J. van & Martin N.I. (2022), Synthetic studies with bacitracin A and preparation of analogues containing alternative zinc binding groups, ChemBioChem 23(24): e202200547.
- Gao Y., Haren M.J., Buijs N., Innocent I., Zhang Y., Sartini D., Campagna R., Emanuelli M., Parsons R.B., Jespers W., Gutiérrez-de-Terán H., Westen G.J.P. van & Martin N.I. (2021), Potent inhibition of nicotinamide N-Methyltransferase by alkene-linked bisubstrate mimics bearing electron deficient aromatics, Journal of Medicinal Chemistry 64(17): 12938-12963.
- Haren M.J. van, Zhang Y., Thijssen V., Buijs N.P., Gao Y., Mateuszuk L., Fedak F.A., Kij A., Campagna R., Sartini D., Emanuelli M., Chlopicki S., Jongkees S.A.K. & Martin N.I. (2021), Macrocyclic peptides as allosteric inhibitors of nicotinamide n-methyltransferase (NNMT), RSC Chemical Biology 2(5): 1546-1555.
- Haren M.J. van, Gao Y., Buijs N., Campagna R., Sartini D., Emanuelli M., Mateuszuk L., Kij A., Chlopicki S., Martinez de Castilla P.E., Schiffelers R. & Martin N.I. (2021), Esterase-sensitive prodrugs of a potent bisubstrate inhibitor of Nicotinamide N-Methyltransferase (NNMT) display cellular activity, Biomolecules 11(9): 1357.