Hendrikus Tanke
Emeritus hoogleraar Analytische cytologie
- Naam
- Prof.dr. H.J. Tanke
- Telefoon
- +31 71 526 9201
- h.j.tanke@lumc.nl
- ORCID iD
- 0000-0001-8922-6492
Tot december 2017 Hoogleraar-Afdelingshoofd Moleculaire Celbiologie, lid bestuur Divisie 4 en trekker LUMC research-profiel 'Biomedical Imaging'. Aanstelling als hoogleraar bij de Faculteit Wiskunde en Natuurwetenschappen Universiteit Leiden (2012), Medical Delta professor via nulaanstelling TU Delft (2013), sinds 2014 lid directie Genomescan (spin-off LUMC).
Tot december 2017 Hoogleraar-Afdelingshoofd Moleculaire Celbiologie, lid bestuur Divisie 4 en trekker LUMC research-profiel 'Biomedical Imaging'. Aanstelling als hoogleraar bij de Faculteit Wiskunde en Natuurwetenschappen Universiteit Leiden (2012), Medical Delta professor via nulaanstelling TU Delft (2013), sinds 2014 lid directie Genomescan (spin-off LUMC).
Analytische Cytologie
Leerstoel: Analytische Cytologie. Ontwikkeling en toepassing van geavanceerde microscopische methoden en fluorescentie technologie om de moleculaire samenstelling van gezonde en zieke cellen te ontrafelen met als doel nieuwe diagnostische methoden en therapievormen te kunnen ontwikkelen.
Wetenschappelijke carrière
Doctoraal Biochemie Universiteit Utrecht (1976)
PhD in 1983: Universiteit Leiden, titel: 'Cytochemical and Cytometric Methods for DNA and RNA analysis (Promotor: P. van Duijn, J.S. Ploem)'
1987-1992: visiting professor Universiteit Brussel, Bologna, Urbino en Hannover
1992: Benoeming als hoogleraar Analytische Cytologie in Leiden. Titel oratie: “Cellen onder het microscoop: van kijken naar vorm tot meten aan moleculen”
Dubbelaanstelling als hoogleraar Leiden (WenN Faculteit) en TUDelft, resp. 2012 en 2013
Prijzen en eervolle benoemingen
- CE-Alken-Prijs ('Deutsche Urologie') in 1982
- NWO Pionier (voorloper VICI) in 1989
- Membership services award 'International Society for Advancement of Cytometry' in 2008
- Ridder in de Orde van de Nederlandse Leeuw bij emeritaat in 2017
Emeritus hoogleraar Analytische cytologie
- Faculteit Geneeskunde
- Divisie 4
- Cel en Chemische biologie
- Sedlmeier, A.; Hlavacek, A.; Birner, L.; Mickert, M.J.; Muhr, V.; Hirsch, T.; Corstjens, P.L.A.M.; Tanke, H.J.; Soukka, T. & Gorris, H.H. (2016), Highly Sensitive Laser Scanning of Photon-Upconverting Nanoparticles on a Macroscopic Scale, Analytical Chemistry 88(3): 1835-1841.
- Fougere, A.; Jackson, A.P.; Bechtsi, D.P.; Braks, J.A.M.; Annoura, T.; Fonager, J.; Spaccapelo, R.; Ramesar, J.; Chevalley-Maurel, S.; Klop, O.; Laan, A.M.A. van der; Tanke, H.J.; Kocken, C.H.M.; Pasini, E.M.; Khan, S.M.; Bohme, U.; Ooij, C. van; Otto, T.D.; Janse, C.J. & Franke-Fayard, B. (2016), Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole, PLoS Pathogens 12(11).
- Boer, S.L. den; Osch-Gevers, M. van; Ingen, G. van; Marchie Sarvaas, G.J. du; Iperen, G.G. van; Tanke, R.B.; Backx, A.P.C.M.; Harkel, A.D.J. ten; Helbing, W.A.; Delhaas, T.; Bogers, A.J.J.C.; Rammeloo, L.A.J. & Dalinghaus, M. (2015), Management of children with dilated cardiomyopathy in The Netherlands: Implications of a low early transplantation rate, Journal of Heart and Lung Transplantation 34(7): 963-969.
- Lin, J.W.; Spaccapelo, R.; Schwarzer, E.; Sajid, M.; Annoura, T.; Deroost, K.; Ravelli, R.B.G.; Aime, E.; Capuccini, B.; Mommaas-Kienhuis, A.M.; O'Toole, T.; Prins, F.; Franke-Fayard, B.M.D.; Ramesar, J.; Chevalley-Maurel, S.; Kroeze, H.; Koster, A.J.; Tanke, H.J.; Crisanti, A.; Langhorne, J.; Arese, P.; Steen, P.E. van den; Janse, C.J. & Khan, S.M. (2015), Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance, Journal of Experimental Medicine 212(6): 893-903.
- Koning R.I., Faas F.G., Boonekamp M., Visser B. de, Janse J., Wiegant J.C.A.G., Breij A. de, Willemse J., Nibbering P.H., Tanke H.J. & Koster A.J. (2014), MAVIS: An integrated system for live microscopy and vitrification, Ultramicroscopy 143: 67-76.
- Karkampouna, S.; Kruithof, B.P.T.; Kloen, P.; Obdeijn, M.C.; Laan, A.M.A. van der; Tanke, H.J.; Kemaladewi, D.U.; Hoogaars, W.M.H.; Hoen, P.A.C. 't; Aartsma-Rus, A.; Clark, I.M.; Dijke, P. ten; Goumans, M.J. & Kruithof-de Julio, M. (2014), Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGF beta Type 1 Receptor Modulation by Antisense Oligonucleotides, Molecular Therapy - Nucleic Acids 3.
- Tanke Hans J., Zuiderwijk Michel, Wiesmeijer Karien C., Breedveld Robert N., Abrams William R., de Dood Claudia J., Fat Elisa M. Tjon Kon & Corstjens Paul L. A. M. (2014), The use of upconverting phosphors in point-of-care (POC) testing, Proceedings of SPIE 8947.
- Corstjens, P.L.A.M.; Dood, C.J. de; Priest, J.W.; Tanke, H.J.; Handali, S. & Cysticercosis Working Grp Peru (2014), Feasibility of a Lateral Flow Test for Neurocysticercosis Using Novel Up-Converting Nanomaterials and a Lightweight Strip Analyzer, PLoS Neglected Tropical Diseases 8(7).
- Koning, R.I.; Faas, F.G.; Boonekamp, M.; Visser, B. de; Janse, J.; Wiegant, J.C.; Breij, A. de; Willemse, J.; Nibbering, P.H.; Tanke, H.J. & Koster, A.J. (2014), MAVIS: An integrated system for live microscopy and vitrification.
- Corstjens, P.L.A.M.; Dood, C.J. de; Kornelis, D.; Fat, E.M.T.K.; Wilson, R.A.; Kariuki, T.M.; Nyakundi, R.K.; Loverde, P.T.; Abrams, W.R.; Tanke, H.J.; Lieshout, L. van; Deelder, A.M. & Dam, G.J. van (2014), Tools for diagnosis, monitoring and screening of Schistosoma infections utilizing lateral-flow based assays and upconverting phosphor labels, Parasitology 141(14): 1841-1855.
- Chen, Z.Y.; Abrams, W.R.; Geva, E.; Dood, C.J. de; Gonzalez, J.M.; Tanke, H.J.; Niedbala, R.S.; Zhou, P.; Malamud, D. & Corstjens, P.L.A.M. (2013), Development of a Generic Microfluidic Device for Simultaneous Detection of Antibodies and Nucleic Acids in Oral Fluids, BioMed Research International.
- Dam, G.J. van; Dood, C.J. de; Lewis, M.; Deelder, A.M.; Lieshout, L. van; Tanke, H.J.; Rooyen, L.H. van & Corstjens, P.L.A.M. (2013), A robust dry reagent lateral flow assay for diagnosis of active schistosomiasis by detection of Schistosoma circulating anodic antigen, Experimental Parasitology 135(2): 274-282.
- Ellenbroek, J.H.; Tons, H.A.; Graaf, N. de; Loomans, C.J.; Engelse, M.A.; Vrolijk, H.; Voshol, P.J.; Rabelink, T.J.; Carlotti, F. & Koning, E.J. de (2013), Topologically Heterogeneous Beta Cell Adaptation in Response to High-Fat Diet in Mice, PLoS ONE 8(2).
- Huijbers, M.G.; Zhang, W.; Klooster, R.; Niks, E.H.; Friese, M.B.; Straasheijm, K.R.; Thijssen, P.E.; Vrolijk, H.; Plomp, J.J.; Vogels, P.; Losen, M.; Maarel, S.M. van der; Burden, S.J. & Verschuuren, J.J. (2013), MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4, Proceedings of the National Academy of Sciences 110(51): 20783-20788.
- Vu, T.H.K.; Bronkhorst, I.H.G.; Versluis, M.; Marinkovic, M.; Duinen, S.G. van; Vrolijk, J.; Luyten, G.P.M. & Jager, M.J. (2013), Analysis of Inflammatory Cells in Uveal Melanoma after Prior Irradiation, Investigative Ophthalmology & Visual Science 54(1): 360-369.
- Chin, P.T.K.; Welling, M.M.; Meskers, S.C.J.; Olmos, R.A.V.; Tanke, H. & Leeuwen, F.W.B. van (2013), Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence, European Journal of Nuclear Medicine and Molecular Imaging 40(8): 1283-1291.
- Corstjens, P.L.A.M.; Fidder, H.H.; Wiesmeijer, K.C.; Dood, C.J. de; Rispens, T.; Wolbink, G.J.; Hommes, D.W. & Tanke, H.J. (2013), A rapid assay for on-site monitoring of infliximab trough levels: a feasibility study, Analytical and Bioanalytical Chemistry 405(23): 7367-7375.
- Ellenbroek, J.H.; Tons, H.A.; Graaf, N. de; Loomans, C.J.M.; Engelse, M.A.; Vrolijk, H.; Rabelink, T.J.; Carlotti, F. & Koning, E.J.P. de (2012), Beta cell adaptation is topologically heterogeneous throughout the pancreas, Diabetologia 55: S183-S183.
- Dekker, P.; Baalen, L.M. van; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age, Journals of Gerontology, Series A 67(5): 456-464.
- van der Laan Annelies M. A., van Gemert Alice M. C., Dirks Roeland W., Noordermeer Jasprina N., Fradkin Lee G., Tanke Hans J. & Jost Carolina R. (2012), mRNA cycles through hypoxia-induced stress granules in live Drosophila embryonic muscles, International Journal of Developmental Biology 56(9): 701-709.
- Giessen, M. van de; Laan, A. van der; Hendriks, E.A.; Vidorreta, M.; Reiber, J.H.C.; Jost, C.R.; Tanke, H.J. & Lelieveldt, B.P.F. (2012), Fully Automated Attenuation Measurement and Motion Correction in FLIP Image Sequences, IEEE Transactions on Medical Imaging 31(2): 461-473.
- Dekker, P.; Meissner, A.; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Deelder, A.M.; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Human in vivo longevity is reflected in vitro by differential metabolism as measured by H-1-NMR profiling of cell culture supernatants.
- Dekker, P.; Baalen, L.M. van; Dirks, R.W.; Slagboom, P.E.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age, Journals of Gerontology, Series A 67(5): 456-464.
- Dekker, P.; Gunn, D.; McBryan, T.; Dirks, R.W.; Heemst, D. van; Lim, F.L.; Jochemsen, A.G.; Verlaan-de Vries, M.; Nagel, J.; Adams, P.D.; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2012), Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts, Mechanisms of Ageing and Development 133(7): 498-507.
- Graveland, A.P.; Braakhuis, B.J.M.; Eerenstein, S.E.J.; Bree, R. de; Bloemena, E.; Maaker, M. de; Brekel, M.W.M. van den; Dijk, F.; Mesker, W.E.; Tanke, H.J.; Leemans, C.R. & Brakenhoff, R.H. (2012), Molecular diagnosis of minimal residual disease in head and neck cancer patients, Cellular Oncology 35(5): 367-375.
- Bronkhorst, I.H.G.; Ly, L.V.; Jordanova, E.S.; Vrolijk, J.; Versluis, M.; Luyten, G.P.M. & Jager, M.J. (2011), Detection of M2-Macrophages in Uveal Melanoma and Relation with Survival, Investigative Ophthalmology & Visual Science 52(2): 643-650.
- Hutteman, M.; Mieog, J.S.D.; Vorst, J.R. van der; Dijkstra, J.; Kuppen, P.J.K.; Laan, A.M.A. van der; Tanke, H.J.; Kaijzel, E.L.; Que, I.; Velde, C.J.H. van de; Lowik, C.W.G.M. & Vahrmeijer, A.L. (2011), Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin alpha(v)beta(3) expression in a syngeneic rat model, EJSO - European Journal of Surgical Oncology 37(3): 252-257.
- Hutteman, M.; Mieog, J.S.D.; Vorst, J.R. van der; Dijkstra, J.; Kuppen, P.J.K.; Laan, A.M.A. van der; Tanke, H.J.; Kaijzel, E.L.; Que, I.; Velde, C.J.H. van de; Lowik, C.W.G.M. & Vahrmeijer, A.L. (2011), Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin α(v)β(3) expression in a syngeneic rat model.
- Corstjens, P.L.A.M.; Dood, C.J. de; Ploeg-van Schip, J.J. van der; Wiesmeijer, K.C.; Riuttamaki, T.; Meijgaarden, K.E. van; Spencer, J.S.; Tanke, H.J.; Ottenhoff, T.H.M. & Geluk, A. (2011), Lateral flow assay for simultaneous detection of cellular- and humoral immune responses., Clinical Biochemistry.
- Dekker, P.; Lange, M.J. de; Dirks, R.W.; Heemst, D. van; Tanke, H.J.; Westendorp, R.G.J. & Maier, A.B. (2011), Relation Between Maximum Replicative Capacity and Oxidative Stress-Induced Responses in Human Skin Fibroblasts In Vitro., Journals of Gerontology, Series A.
- Corstjens, P.L.A.M.; Dood, C.J. de; Ploeg-van Schip, J.J. van der; Wiesmeijer, K.C.; Riuttamaki, T.; Meijgaarden, K.E. van; Spencer, J.S.; Tanke, H.J.; Ottenhoff, T.H.M. & Geluk, A. (2011), Lateral flow assay for simultaneous detection of cellular- and humoral immune responses, Clinical Biochemistry 44(14-15): 1241-1246.
- Ly, L.V.; Bronkhorst, I.H.G.; Beelen, E. van; Vrolijk, J.; Taylor, A.W.; Versluis, M.; Luyten, G.P.M. & Jager, M.J. (2010), Inflammatory Cytokines in Eyes with Uveal Melanoma and Relation with Macrophage Infiltration, Investigative Ophthalmology & Visual Science 51(11): 5445-5451.
- Smeenk, G.; Wiegant, W.W.; Vrolijk, H.; Solari, A.P.; Pastink, A. & Attikum, H. van (2010), The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage, Journal of Cell Biology 190(5): 741-749.
- Vogelaar, F.J.; Mesker, W.E.; Rijken, A.M.; Pelt, G.W. van; Leeuwen, A.M. van; Tanke, H.J.; Tollenaar, R.A. & Liefers, G.J. (2010), Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study, BMC Cancer 10.
- Wiegant J, Brouwer AK, Tanke HJ & Dirks RW (2010), Visualizing nucleic acids in living cells by fluorescence in vivo hybridization., Methods in Molecular Biology 659: 239-46.
- Jonsdottir, A.B.; Dirks, R.W.; Vrolijk, J.; Ogmundsdottir, H.M.; Tanke, H.J.; Eyfjord, J.E. & Szuhai, K. (2010), Centriole movements in mammalian epithelial cells during cytokinesis, BMC Cell Biology 11.
- Vogelaar, F.J.; Mesker, W.E.; Rijken, A.M.; Pelt, G.W. van; Leeuwen, A.M. van; Tanke, H.J.; Tollenaar, R.A. & Liefers, G.J. (2010), Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study., BMC Cancer 10: 153.
- Reijnders, C.M.A.; Waaijer, C.J.F.; Hamilton, A.; Buddingh, E.; Dijkstra, P.D.S.; Ham, S.J.; Bakker, E.; Szuhai, K.; Karperien, M.; Hogendoorn, P.C.W.; Stringer, S.E. & Bovee, J.V.M.G. (2010), Osteochondroma Formation: Haploinsufficiency or Two Hits?, Modern Pathology 23: 26A26A.
- Reijnders, C.M.A.; Waaijer, C.J.F.; Hamilton, A.; Buddingh, E.; Dijkstra, P.D.S.; Ham, S.J.; Bakker, E.; Szuhai, K.; Karperien, M.; Hogendoorn, P.C.W.; Stringer, S.E. & Bovee, J.V.M.G. (2010), Osteochondroma Formation: Haploinsufficiency or Two Hits?, Laboratory Investigation 90: 26A26A.
- Romeo, S.; Duim, R.A.J.; Bridge, J.A.; Mertens, F.; Jong, D. de; Cin, P. dal; Wijers-Koster, P.M.; Debiec-Rychter, M.; Sciot, R.; Rosenberg, A.; Szuhai, K. & Hogendoorn, P.C.W. (2010), Heterogeneous and Complex Rearragements of the Long Arm of Chromosome 6 in Chondromyxoid Fibroma, Modern Pathology 23: 27A27A.
- Romeo, S.; Duim, R.A.J.; Bridge, J.A.; Mertens, F.; Jong, D. de; Cin, P. dal; Wijers-Koster, P.M.; Debiec-Rychter, M.; Sciot, R.; Rosenberg, A.; Szuhai, K. & Hogendoorn, P.C.W. (2010), Heterogeneous and Complex Rearragements of the Long Arm of Chromosome 6 in Chondromyxoid Fibroma, Laboratory Investigation 90: 27A27A.
- Szuhai, K. (2010), A VARIANT EWING SARCOMA: NOVEL TRANSLOCATION INVOLVING THE NFATC2 GENE IN MULTIPLE CASES, Analytical Cellular Pathology / Cellular Oncology 32(3): 169-169.
- Doekhie, F.S.; Mesker, W.E.; Kuppen, P.J.; Leeuwen, G.A. van; Morreau, H.; Bock, G.H. de; Putter, H.; Tanke, H.J.; Velde, C.J. van de & Tollenaar, R.A. (2010), Detailed examination of lymph nodes improves prognostication in colorectal cancer, International Journal of Cancer 126(11): 2644-2652.
- Mesker WE, Liefers GJ, Junggeburt JMC, van Pelt GW, Alberici P, Kuppen PJK, Miranda NF, van Leeuwen KAM, Morreau H & Szuhai K (2009), Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients, Analytical Cellular Pathology / Cellular Oncology 31(3): 169-178.
- Mesker W, Liefers G, Morreau H, Tanke H & Tollenaar R (2009), STROMA PRODUCTION AND DOWNREGULATION OF SMAD4 CORRELATES WITH POOR SURVIVAL FOR STAGE I-II COLON CANCER PATIENTS, Annals of Oncology 20: 19-20.
- Jonsdottir AB, Vreeswijk MPG, Wolterbeek R, Devilee P, Tanke HJ, Eyfjord JE & Szuhai K (2009), BRCA2 heterozygosity delays cytokinesis in primary human fibroblasts, Analytical Cellular Pathology / Cellular Oncology 31(3): 191-201.
- Hambach L, Ling KW, Pool J, Aghai Z, Blokland E, Tanke HJ, Bruijn JA, Halfwerk H, Van Boven H & Wieles B (2009), Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy, Blood 113(12): 2715-2722.
- Szuhai K, IJszenga M, de Jong D, Karseladze A, Tanke HJ & Hogendoorn PCW (2009), Novel, Cloned Translocation Partner in Ewing Sarcoma Couples Its Function to Oncology, Laboratory Investigation 89: 23A23A.
- Szuhai K, IJszenga M, de Jong D, Karseladze A, Tanke HJ & Hogendoorn PCW (2009), Novel, Cloned Translocation Partner in Ewing Sarcoma Couples Its Function to Oncology, Modern Pathology 22: 23A23A.
- Szuhai K, de Jong J, Bovee JVMG, Jennes I, Wuyts W, Wiweger M, Tanke HJ & Hogendoorn PCW (2009), Somatic Mosaicism Is Causative in EXT1/2 Negative Multiple Osteochondroma Detected by Tiling Resolution Array-CGH, Laboratory Investigation 89: 23A23A.
- Szuhai K, de Jong J, Bovee JVMG, Jennes I, Wuyts W, Wiweger M, Tanke HJ & Hogendoorn PCW (2009), Somatic Mosaicism Is Causative in EXT1/2 Negative Multiple Osteochondroma Detected by Tiling Resolution Array-CGH, Modern Pathology 22: 23A23A.
- Dekker P, Maier AB, van Heemst D, de Koning-Treurniet C, Blom J, Dirks RW, Tanke HJ & Westendorp RGJ (2009), Stress-induced responses of human skin fibroblasts in vitro reflect human longevity, Aging Cell 8(5): 595-603.
- Szuhai, K.; Ijszenga, M.; Jong, D. de; Karseladze, A.; Tanke, H.J. & Hogendoorn, P.C.W. (2009), The NFATc2 Gene Is Involved in a Novel Cloned Translocation in a Ewing Sarcoma Variant That Couples Its Function in Immunology to Oncology, Clinical Cancer Research 15(7): 2259-2268.
- Knijnenburg J, Oberstein SAJL, Frei K, Lucas T, Gijsbers ACJ, Ruivenkamp CAL, Tanke HJ & Szuhai K (2009), A homozygous deletion of a normal variation locus in a patient with hearing loss from non-consanguineous parents, Journal of Medical Genetics 46(6): 412-417.
- van Gemert AMC, van der Laan AMA, Pilgram GSK, Fradkin LG, Noordermeer JN, Tanke HJ & Jost CR (2009), In Vivo Monitoring of mRNA Movement in Drosophila Body Wall Muscle Cells Reveals the Presence of Myofiber Domains, PLoS ONE 4(8).
- van Gemert AMC, Jost CR, van der Laan AMA, Dirks RW, Reiber JHC, Tanke HJ & Lelieveldt BPF (2009), IDENTIFICATION OF CELLULAR DYNAMIC PATTERNS RESULTING FROM REPETITIVE PHOTOBLEACHING USING INDEPENDENT COMPONENT ANALYSIS, 2009 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, VOLS 1 AND 2: 1382-1385.
- (2009), IDENTIFICATION OF CELLULAR DYNAMIC PATTERNS RESULTING FROM REPETITIVE PHOTOBLEACHING USING INDEPENDENT COMPONENT ANALYSIS.
- Noppe G, Dekker P, de Koning-Treurniet C, Blom J, van Heemst D, Dirks RW, Tanke HJ, Westendorp RGJ & Maier AB (2009), Rapid Flow Cytometric Method for Measuring Senescence Associated beta-Galactosidase Activity in Human Fibroblasts, Cytometry Part A 75A(11): 910-916.
- Brouwer AK, Schimmel J, Wiegant JCAG, Vertegaal ACO, Tanke HJ & Dirks RW (2009), Telomeric DNA Mediates De Novo PML Body Formation, Molecular Biology of the Cell 20(22): 4804-4815.
- Wiesmeijer K, Krouwels IM, Tanke HJ & Dirks RW (2008), Chromatin movement visualized with photoactivable GFP-labeled histone H4, Differentiation 76(1).
- Tanke H, Mesker W, Morreau H & Tollenaer R (2008), New prognostic parameters in colorectal cancer, Analytical Cellular Pathology / Cellular Oncology 30(2).
- Raz V, Vermolen BJ, Garini Y, Onderwater JJM, Mommaas-Kienhuis MA, Koster AJ, Young IT, Tanke H & Dirks RW (2008), The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells, Journal of Cell Science 121(24).
- Corstjens PLAM, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM & van Dam GJ (2008), Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum, Journal of Clinical Microbiology 46(1).
- Knijnenburg, J.; Lesnik-Oberstein, S.; Frei, K.; Gijsbers, A.; Ruivenkamp, C.; Tanke, H. & Szuhai, K. (2008), Disease-causing homozygous deletion of a normal variation locus, Analytical Cellular Pathology 30(3).
- Goobie S, Knijnenburg J, FitzPatrick D, Sharkey FH, Lionel AC, Marshall CR, Azam T, Shago M, Chong K, Mendoza-Londono R, den Hollander NS, Ruivenkamp C, Maher E, Tanke HJ, Szuhai K, Wintle RF & Scherer SW (2008), Molecular and clinical characterization of de novo and familial cases with microduplication 3q29: guidelines for copy number variation case reporting, Cytogenetic and Genome Research 123(1-4): 65-78.
- Corstjens PLAM, Zuiderwijk M, Tanke HJ, Schip JJVV, Ottenhoff THM & Geluk A (2008), A user-friendly, highly sensitive assay to detect the IFN-gamma secretion by T cells, Clinical Biochemistry 41(6).
- Khan S., Bijker M.S., Weterings J.J., Tanke H.J., Adema G.J., Hall T. van, Drijfhout J.W., Melief C.J.M., Overkleeft H.S., Marel G.A. van der, Filippov D.V., Burg M.J.M. van der & Ossendorp F. (2007), Distinct Uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells, Journal of Biological Chemistry 282(29): 21145-21159.
- Kriek M, Knijnenburg J, White SJ, Rosenberg C, den Dunnen JT, van Ommen GJB, Tanke HJ, Breuning MH & Szuhai K (2007), Diagnosis of genetic abnormalities in developmentally delayed patients: A new strategy combining MLPA and array-CGH, American Journal of Medical Genetics Part A 143A(6).
- Knijnenburg J, Ruivenkamp C, Lankester A, Tanke H & Szuhai K (2007), High resolution molecular analysis of a ring chromosome reveals unexpected alterations: Lessons for routine diagnosis, Analytical Cellular Pathology / Cellular Oncology 29(2).
- Mokkapati VK, Niedbala RS, Kardos K, Perez RJ, Guo M, Tanke HJ & Corstjens PLAM (2007), Evaluation of UPlink-RSV - Prototype rapid antigen test for detection of respiratory syncytial virus infection, Annals of the New York Academy of Sciences 1098.
- Rossi S, Szuhai K, Ijszenga M, Tanke HJ, Zanatta L, Sciot R, Fletcher CDM, Tos APD & Hogencloorn PCW (2007), EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma, Clinical Cancer Research 13(24).
- Corstjens PLAM, Chen ZY, Zuiderwijk M, Bau HH, Abrams WR, Malamud D, Niedbala RS & Tanke HJ (2007), Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB), Annals of the New York Academy of Sciences 1098.
- Abrams WR, Barber CA, McCann K, Tong G, Chen ZY, Mauk MG, Wang J, Volkov A, Bourdelle P, Corstjensd PLAM, Zuiderwijk M, Kardos K, Li S, Tanke HJ, Niedbala RS, Malamud D & Bau H (2007), Development of a microfluidic device for detection of pathogens in oral samples using upconverting phosphor technology (UPT), Annals of the New York Academy of Sciences 1098.
- Knijnenburg J, van der Burg M, Tanke HJ & Szuhai K (2007), Optimized amplification and fluorescent labeling of small cell samples for genomic array-CGH, Cytometry Part A 71A(8).
- Tanke HJ (2007), Genomics and proteomics - The potential role of oral diagnostics, Annals of the New York Academy of Sciences 1098.
- Knijnenburg J, van Haeringen A, Hansson KBM, Lankester A, Smit MJM, Belfroid RDM, Bakker E, Rosenberg C, Tanke HJ & Szuhai K (2007), Ring chromosome formation as a novel escape mechanism in patients with inverted duplication and terminal deletion, European Journal of Human Genetics 15(5).
- Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJM, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH & Ossendorp F (2007), Distinct uptake mechanisms but similar intracellular processing of two different Toll-like receptor ligand-peptide conjugates in dendritic cells, Journal of Biological Chemistry 282(29).
- Szuhai K, IJszenga M, Knijnenburg J, Dijkstra S, de Schepper A, Tanke HJ & Hogendoorn PCW (2007), Does parosteal liposarcoma differ from other atypical lipomatous tumors/well-differentiated liposarcomas? A molecular cytogenetic study using combined multicolor COBRA-FISH karyotyping and array-based comparative genomic hybridization, Cancer Genetics and Cytogenetics 176(2).
- Szuhai K, IJszenga M, Tanke HJ, Taminiau AHM, de Schepper A, van Duinen SG, Rosenberg C & Hogendoorn PCW (2007), Detection and molecular cytogenetic characterization of a novel ring chromosome in a histological variant of Ewing sarcoma, Cancer Genetics and Cytogenetics 172(1).
- Mesker WE, Junggeburt JMC, Szuhai K, de Heer P, Morreau H, Tanke HJ & Tollenaar RAEM (2007), The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage, Analytical Cellular Pathology / Cellular Oncology 29(5).
- Rosenberg C, Knijnenburg J, Bakker E, Vianna-Morgante AM, Fiegler H, Carter NP, Bijlsma EK, van Haeringen A, Szuhai K & Tanke HJ (2006), Array-CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents, Journal of Medical Genetics 43(2).
- Dirks RW & Tanke HJ (2006), Advances in fluorescent tracking of nucleic acids in living cells, BioTechniques 40(4).
- Postma R, Van Marion R, Van Duin M, Vissers KJ, Wink JC, Schroder FH, Tanke HJ, Szuhai K, Van Der Kwast TH & Van Dekken H (2006), Array-based genomic analysis of screen-detected Gleason score 6 and 7 prostatic adenocarcinomas, Anticancer Research 26(2A).
- van Dekken H, Wink JC, Vissers KJ, van Marion R, Koppert LB, Tilanus HW, Siersema PD, Tanke HJ, Szuhai K & Hop WCJ (2006), Genomic analysis of early adenocarcinoma of the esophagus or gastroesophageal junction: Tumor progression is associated with alteration of 1q and 8p sequences, Genes, Chromosomes and Cancer 45(5).
- Doekhie FS, Kuppen PJK, Peeters KCMJ, Mesker WE, van Soest RA, Morreau H, de Velde CJH, Tanke HJ & Tollenaar RAEM (2006), Prognostic relevance of occult tumour cells in lymph nodes in colorectal cancer, EJSO - European Journal of Surgical Oncology 32(3).
- Pelikan DM, Kanhai HH, De Groot-Swings GM, Mesker WE, Tanke HJ & Scherjon SA (2006), Fetomaternal hemorrhage in relation to chorionic villus sampling revisited, Prenatal Diagnosis 26(3).
- van Dekken H, Vissers K, Tilanus HW, Kuo WL, Tanke HJ, Rosenberg C, IJszenga M & Szuhai K (2006), Genomic array and expression analysis of frequent high-level amplifications in adenocarcinomas of the gastro-esophageal junction, Cancer Genetics and Cytogenetics 166(2).
- Szuhai K, IJszenga M, Tanke HJ, Rosenberg C & Hogendoorn PCW (2006), Molecular cytogenetic characterization of four previously established and two newly established Ewing sarcoma cell lines, Cancer Genetics and Cytogenetics 166(2).
- van Dieren JM, Wink JC, Vissers KJ, van Marion R, Hoogmans MMCP, Dinjens WNM, Schouten WR, Tanke HJ, Szuhai K, Kuipers EJ, van der Woude CJ & Dekken H (2006), Chromosomal and microsatellite instability of adenocarcinomas and dysplastic lesions (DALM) in ulcerative colitis, Diagnostic Molecular Pathology 15(4).
- Keijser S, de Keizer RJW, Prins FA, Tanke HJ, van Rooijen N, Vrensen GFJM & Jager MJ (2006), A new model for limbal transplantation using E-GFP for follow-up of transplant survival, Experimental Eye Research 83(5).
- Rozeman, L.B.; Szuhai, K.; Schrage, Y.M.; Rosenberg, C.; Tanke, H.J.; Taminiau, A.H.M.; Cleton-Jansen, A.M.; Bovee, J.V.M.G. & Hogendoorn, P.C.W. (2006), Array-comparative genomic hybridization of central chondrosarcoma - Identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations, Cancer 107(2).
- Kriek M, Szuhai K, Kant SG, White SJ, Dauwerse H, Fiegler H, Carter NP, Knijnenburg J, den Dunnen JT, Tanke HJ, Breuning MH & Rosenberg C (2006), A complex rearrangement on chromosome 22 affecting both homologues; haplo-insufficiency of the Cat eye syndrome region may have no clinical relevance, Human Genetics 120(1).
- Raap AK & Tanke HJ (2006), COmbined Binary RAtio fluorescence in situ hybridiziation (COBRA-FISH): development and applications, Cytogenetic and Genome Research 114(3-4).
- Stewenius Y, Tanke HJ, Wiegant J & Gisselsson D (2006), Cryptic terminal chromosome rearrangements in colorectal carcinoma cell lines detected by subtelomeric FISH analysis, Cytogenetic and Genome Research 114(3-4).
- Mesker WE, Vrolijk H, Sloos WCR, Tollenaar RAEM & Tanke HJ (2006), Detection of tumor cells in bone marrow, peripheral blood and lymph nodes by automated imaging devices, Analytical Cellular Pathology / Cellular Oncology 28(4).
- Raz V, Carlotti F, Vermolen BJ, van der Poel E, Sloos WCR, Knaan-Shanzer S, de Vries AAF, Hoeben RC, Young IT, Tanke HJ, Garini Y & Dirks RW (2006), Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells, Journal of Cell Science 119(20).
- Skakun VV, Novikov EG, Apanasovich VV, Tanke HJ, Deelder AM & Mayboroda OA (2006), Initial guesses generation for fluorescence intensity distribution analysis, European Biophysics Journal 35(5).
- kalayda G.V., Zhang G., Abraham T.E., Tanke H.J. & Reedijk J. (2005), Application of fluorescence microscopy for investigation of cellular distribution of dinuclear platinum anticancer drugs, Journal of Medicinal Chemistry 48(16): 5191-5202.
- Kalayda G.V., Jansen B.A.J., Wielaard P., Tanke H.J. & Reedijk J. (2005), Dinuclear platinum anticancer complexes with fluorescent N,N'-bis(aminoalkyl)-1,4-diaminoanthraquinones: cellular processing in two cisplatin-resistant cell lines reflects the differences in their resistance profiles, Journal of Biological Inorganic Chemistry 10: 305-315.
- Knijnenburg J, van der Burg M, Nilsson P, van Amstel HKP, Tanke H & Szuhai K (2005), Rapid detection of genomic imbalances using micro-arrays consisting of pooled BACs covering all human chromosome arms, Nucleic Acids Research 33(18).
- Aigouy L, Mortier M, Gierak J, Bourhis E, De Wilde Y, Corstjens P & Tanke HJ (2005), Field distribution on metallic and dielectric nanoparticles observed with a fluorescent near-field optical probe, Journal of Applied Physics 97(10).
- Kalayda GV, Jansen BAJ, Wielaard P, Tanke HJ & Reedijk J (2005), Dinuclear platinum anticancer complexes with fluorescent N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones: cellular processing in two cisplatin-resistant cell lines reflects the differences in their resistance profiles, Journal of Biological Inorganic Chemistry 10(3).
- Doekhie FS, Peeters KCMJ, Kuppen PJK, Mesker WE, Tanke HJ, Morreau H, van de Velde CJH & Tollenaar RAEM (2005), The feasibility and reliability of sentinel node mapping in colorectal cancer, EJSO - European Journal of Surgical Oncology 31(8).
- Tong M, Jacobi CE, van de Rijke FM, Kuijper S, van de Werken S, Lowary TL, Hokke CH, Appelmelk BJ, Nagelkerke NJD, Tanke HJ, van Gijlswijkh RPM, Veuskens J, Kolk AHJ & Raap AK (2005), A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera, Journal of Immunological Methods 301(1-2).
- de Pauw ESD, Roelofs H, Zwinderman A, van Houwelingen JC, Fibbe WE, de Knijff P, Pearson PL & Tanke HJ (2005), Studying the biological and technical sources of variation in telomere length of individual chromosomes, Cytometry Part A 65A(1).
- Knijnenburg J, Szuhai K, Giltay J, Molenaar L, Sloos W, Poot M, Tanke HJ & Rosenberg C (2005), Insights from genomic microarrays into structural chromosome rearrangements, American Journal of Medical Genetics Part A 132A(1).
- Kalayda GV, Zhang GF, Abraham T, Tanke HJ & Reedijk J (2005), Application of fluorescence microscopy for investigation of cellular distribution of dinuclear platinum anticancer drugs, Journal of Medicinal Chemistry 48(16).
- Doekhie TS, Mesker WE, van Krieken JHJM, Kok NFM, Hartgrink HH, Kranenbarg EK, Putter H, Kuppen PJK, Tanke HJ, Tollenaar RAEM & van de Velde CJH (2005), Clinical relevance of occult tumor cells in lymph nodes from gastric cancer patients, American Journal of Surgical Pathology 29(9).
- Tanke HJ, Dirks RW & Raap T (2005), FISH and immunocytochemistry: towards visualising single target molecules in living cells, Current Opinion in Biotechnology 16(1).
- Krouwels IM, Wiesmeijer K, Abraham TE, Molenaar C, Verwoerd NP, Tanke HJ & Dirks RW (2005), A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain, Journal of Cell Biology 170(4).
- Rosenberg C, Knijnenburg J, Chauffaille M, Brunoni D, Catelani AL, Sloos W, Szuhai K & Tanke HJ (2005), Array CGH detection of a cryptic deletion in a complex chromosome rearrangement, Human Genetics 116(5).
- kalayda G.V., Jansen B.A.J., Molenaar C., Wielaard P., Tanke H.J. & Reedijk J. (2004), Dinuclear platinum complexes with N,N'-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part II. Cellular processing in A2780 cisplatin-resistant juman ovarian carcinoma cells: new insights into the mechanism of resistance, Journal of Biological Inorganic Chemistry 9: 414-422.
- Jansen B.A.J., Wielaard P., Kalayda G.V., Ferrari M., Molenaar C., Tanke H.J., Brouwer J. & Reedijk J. (2004), Dinuclear platinum complexes with N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part I. Synthesis, cytotoxicity, and cellular studies in A2780 human ovarian carcinoma cells, Journal of Biological Inorganic Chemistry 9: 403-413.
- Jansen BAJ, Wielaard P, Kalayda GV, Ferrari M, Molenaar C, Tanke HJ, Brouwer J & Reedijk J (2004), Dinuclear platinum complexes with N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part I. Synthesis, cytotoxicity, and cellular studies in A2780 human ovarian carcinoma cells, Journal of Biological Inorganic Chemistry 9(4).
- Kalayda GV, Jansen BAJ, Molenaar C, Wielaard P, Tanke HJ & Reedijk J (2004), Dinuclear platinum complexes with N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part II. Cellular processing in A2780 cisplatin-resistant human ovarian carcinoma cells: new insights into the mechanism of resistance, Journal of Biological Inorganic Chemistry 9(4).
- Hazelbag, H.M.; Szuhai, K.; Tanke, H.J.; Rosenberg, C. & Hogendoorn, P.C.W. (2004), Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype, Modern Pathology 17(11).
- Szuhai K, Knijnenburg J, Ijszenga M, Tanke HJ, Baatenburg RJ, de Jong RJB, Dekker PBD, Rosenberg C & Hogendoorn PCW (2004), Multicolor fluorescence in situ hybridization analysis of a synovial sarcoma of the larynx with a t(X;18)(p11.2;q11.2) and trisomy-2 and trisomy-8, Cancer Genetics and Cytogenetics 153(1).
- Molenaar C, Abdulle A, Gena A, Tanke HJ & Dirks RW (2004), Poly(A)(+) RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells, Journal of Cell Biology 165(2).
- Wiegant J, Brouwer K, Bezrookove V, Smits S, Raap AK, Bout A & Tanke HJ (2004), Molecular cytogenetic characterization by combined COBRA-FISH and fiber-FISH: application to PER.C6 (R) cells, BioTechniques 37(2).
- Mesker WE, Torrenga H, Sloos WCR, Vrolijk H, Tollenaar RAEM, de Bruin PC, van Diest PJ & Tanke HJ (2004), Supervised automated microscopy increases sensitivity and efficiency of detection of sentinel node micrometastases in patients with breast cancer, Journal of Clinical Pathology 57(9).
- Raap AK, van der Burg MJM, Knijnenburg J, Meershoek E, Rosenberg C, Gray JW, Wiegant J, Hodgson JG & Tanke HJ (2004), Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs, BioTechniques 37(1).
- Mayboroda OA, van Remoortere A, Tanke HJ, Hokke CH & Deelder AM (2004), A new approach for fluorescence correlation spectroscopy (FCS) based immunoassays, Journal of Biotechnology 107(2).
- Heetebrij R.J., Talman E.G., Velzen M.A. van, Gijlswijk R.P.M. van, Snoeijers S.S., Schalk M., Wiegant J.C.A.G., Rijke F.M. van de, Kerkhoven R.M., Raap A.K., Tanke H.J., Reedijk J. & Houthoff H.J. (2003), Platinum (11)-based coordination compounds as nucleic acid labeling reagents:synthesis, reactivity, and applications in hybridization assays, ChemBioChem 4(7): 573-583.
- Pelikan DMV, Mesker WE, Scherjon SA, Kanhai HHH & Tanke HJ (2003), Improvement of the Kleihauer-Betke test by automated detection of fetal erythrocytes in maternal blood, Cytometry 54B(1).
- Zhang YH, Leliveld SR, Kooistra K, Molenaar C, Rohn JL, Tanke HJ, Abrahams JP & Noteborn MHM (2003), Recombinant Apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion, Experimental Cell Research 289(1).
- Paulsson K, Fioretos T, Strombeck B, Mauritzson N, Tanke HJ & Johansson B (2003), Trisomy 8 as the sole chromosomal aberration in myelocytic malignancies: a multicolor and locus-specific fluorescence in situ hybridization study, Cancer Genetics and Cytogenetics 140(1).
- van Dekken H, Alers JC, Damen IAAJ, Vissers KJ, Krijtenburg PJ, Hoedemaeker RF, Wildhagen MF, Hop WCJ, van der Kwast TH, Tanke HJ & Schroder FH (2003), Genetic evaluation of localized prostate cancer in a cohort of forty patients: Gain of distal 8q discriminates between progressors and nonprogressors, Laboratory Investigation 83(6).
- Dirks RW, Molenaar C & Tanke HJ (2003), Visualizing RNA molecules inside the nucleus of living cells, Methods 29(1).
- van de Rijke FM, Heetebrij RJ, Talman EG, Tanke HJ & Raap AK (2003), Fluorescence properties, thermal duplex stability, and kinetics of formation of cyanin platinum DNAs, Analytical Biochemistry 321(1).
- Corstjens PLAM, Zuiderwijk M, Nilsson M, Feindt H, Niedbala RS & Tanke HJ (2003), Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay, Analytical Biochemistry 312(2).
- Engels H, Ehrbrecht A, Zahn S, Bosse K, Vrolijk H, White S, Kalscheuer V, Hoovers JMN, Schwanitz G, Propping P, Tanke HJ, Wiegant J & Raap AK (2003), Comprehensive analysis of human subtelomeres with combined binary ratio labelling fluorescence in situ hybridisation, European Journal of Human Genetics 11(9).
- Heetebrij RJ, Talman EG, Von Velzen MA, Von Gijlswijk RPM, Snoeijers SS, Schalk M, Wiegant J, Von der Rijke F, Kerkhoven RM, Raap AK, Tanke HJ, Reedijk J & Houthoff HJ (2003), Platinum(II)-based coordination compounds as nucleic acid labeling reagents: Synthesis, reactivity, and applications in hybridization assays, ChemBioChem 4(7).
- Paulsson K, Lassen C, Kuric N, Billstrom R, Fioretos T, Tanke HJ & Johansson B (2003), MYC is not overexpressed in a case of chronic myelomonocytic leukemia with MYC-containing double minutes, Leukemia 17(4).
- Roelofs H, de Pauw ESD, Zwinderman AH, Opdam SM, Willemze R, Tanke HJ & Fibbe WE (2003), Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation, Blood 101(1).
- Zuiderwijk M, Tanke HJ, Niedbala RS & Corstjens PLAM (2003), An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology, Clinical Biochemistry 36(5).
- Mesker WE, Doekhie FS, Vrolijk H, Keyzer R, Sloos WCR, Morreau H, O'Kelly PS, de Bock GH, Tollenaar RAEM & Tanke HJ (2003), Automated analysis of multiple sections for the detection of occult cells in lymph nodes, Clinical Cancer Research 9(13).
- Vrolijk H, Sloos W, Mesker W, Franken P, Fodde R, Morreau H & Tanke H (2003), Automated acquisition of stained tissue microarrays for high-throughput evaluation of molecular targets, Journal of Molecular Diagnostics 5(3).
- Molenaar C, Wiesmeijer K, Verwoerd NP, Khazen S, Eils R, Tanke HJ & Dirks RW (2003), Visualizing telomere dynamics in living mammalian cells using PNA probes, EMBO Journal 22(24).
- Bezrookove V, Smits R, Moeslein G, Fodde R, Tanke HJ, Raap AK & Darroudi F (2003), Premature chromosome condensation revisited: A novel chemical approach permits efficient cytogenetic analysis of cancers, Genes, Chromosomes and Cancer 38(2).
- Hattinger CM, Jochemsen AG, Tanke HJ & Dirks RW (2002), Induction of p21 mRNA synthesis after short-wavelength UV light visualized in individual cells by RNA FISH, Journal of Histochemistry and Cytochemistry 50(1).
- Van Gijlswijk RPM, Talman EG, Peekel I, Bloem J, Van Velzen MA, Heetebrij RJ & Tanke HJ (2002), Use of horseradish peroxidase- and fluorescein-modified cisplatin derivatives for simultaneous labeling of nucleic acids and proteins, Clinical Chemistry 48(8).
- de Pauw ESD, Otto SA, Wijnen JT, Vossen JM, van Weel MH, Tanke HJ, Miedema F, Willemze R, Roelofs H & Fibbe WE (2002), Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion, British Journal of Haematology 116(2).
- Barbouti A, Johansson B, Hoglund M, Mauritzson N, Strombeck B, Nilsson PG, Tanke HJ, Hagemeijer A, Mitelman F & Fioretos T (2002), Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced translocations during disease progression, Genes, Chromosomes and Cancer 35(2).
- Wiegant J, van Hall T, van der Burg M, Colombo M, Tanke HJ, Offringa R & Rosenberg C (2002), Application of multicolor fluorescence in situ hybridization analysis for detection of cross-contamination and in vitro progression in commonly used murine tumor cell lines, Cancer Genetics and Cytogenetics 139(2).
- Wiesmeijer K, Molenaar C, Bekeer IMLA, Tanke HJ & Dirks RW (2002), Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not, Journal of Structural Biology 140(1-3).
- Rosenberg C, Geelen E, Ijszenga MJ, Pearson P, Tanke HJ, Dinjens WNM & van Dekken H (2002), Spectrum of genetic changes in gastro-esophageal cancer cell lines determined by an integrated molecular cytogenetic approach, Cancer Genetics and Cytogenetics 135(1).
- Darroudi F, Bezrookove V, Fomina J, Mesker WE, Wiegant JCAG, Raap AK & Tanke HJ (2002), Insights into the sites of X ray and neutron induced chromosomal aberrations in human lymphocytes using COBRA-MFISH, Radiation Protection Dosimetry 99(1-4).
- Snaar SP, Verdijk P, Tanke HJ & Dirks RW (2002), Kinetics of HCMV immediate early mRNA expression in stably transfected fibroblasts, Journal of Cell Science 115(2).
- Brink AATP, Wiegant JCAG, Szuhai K, Tanke HJ, Kenter GG, Fleuren GJ, Schuuring E & Raap AK (2002), Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization, Cancer Genetics and Cytogenetics 134(2).
- Szuhai K, Sandhaus E, Kolkman-Uljee SM, Lemaitre M, Truffert JC, Dirks RW, Tanke HJ, Fleuren GJ, Schuuring E & Raap AK (2001), A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction, American Journal of Pathology 159(5).
- van de Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS & Tanke HJ (2001), Up-converting phosphor reporters for nucleic acid microarrays, Nature Biotechnology 19(3).
- Johansson B, Axelsson P, Billstrom R, Strombeck B, Arheden K, Olofsson T, Cervin A, Adriansson M, Tanke HJ, Mitelman F & Fioretos T (2001), Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: A new clinical entity?, Genes, Chromosomes and Cancer 30(3).
- Alers JC, Krijtenburg PJ, Vis AN, Hoedemaeker RF, Wildhagen MF, Hop WCJ, van der Kwast TH, Schroder FH, Tanke HJ & van Dekken H (2001), Molecular cytogenetic analysis of prostatic adenocarcinomas from screening studies - Early cancers may contain aggressive genetic features, American Journal of Pathology 158(2).
- Corstjens P, Zuiderwijk M, Brink A, Li S, Feindt H, Neidbala RS & Tanke H (2001), Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: A rapid, sensitive DNA test to identify human papillomavirus type 16 infection, Clinical Chemistry 47(10).
- Jin C, Martins C, Jin YS, Wiegant L, Wennerberg L, Dictor M, Gisselsson D, Strombeck B, Fonseca I, Mitelman F, Tanke HJ, Hoglund M & Mertens F (2001), Characterization of chromosome aberrations in salivary gland tumors by FISH, including multicolor COBRA-FISH, Genes, Chromosomes and Cancer 30(2).
- Dirks RW, Molenaar C & Tanke HJ (2001), Methods for visualizing RNA processing and transport pathways in living cells, Histochemistry and Cell Biology 115(1).
- Molenaar C., Teuben J.M., Heetebrij R.J., Tanke H.J. & Reedijk J. (2000), New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy, Journal of Biological Inorganic Chemistry 5: 655-665.
- Szuhai K, Bezrookove V, Wiegant J, Vrolijk J, Dirks RW, Rosenberg C, Raap AK & Tanke HJ (2000), Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH.
- Wiegant J, Bezrookove V, Rosenberg C, Tanke HJ, Raap AK, Zhang HG, Bittner M, Trent JM & Meltzer P (2000), Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization.
- Bezrookove V, Hansson K, van der Burg M, van der Smagt JJ, Hilhorst-Hofstee Y, Wiegant J, Beverstock GC, Raap AK, Tanke H, Breuning MH & Rosenberg C (2000), Individuals with abnormal phenotype and normal G-banding karyotype: improvement and limitations in the diagnosis by the use of 24-colour FISH.
- Alers JC, Rochat J, Krijtenburg PJ, Hop WCJ, Kranse R, Rosenberg C, Tanke HJ, Schroder FH & van Dekken H (2000), Identification of genetic markers for prostatic cancer progression.
- van Gijlswijk RPM, van de Corput MPC, Bezrookove V, Wiegant J, Tanke HJ & Raap AK (2000), Synthesis and purification of horseradish peroxidase-labeled oligonucleotides for tyramide-based fluorescence in situ hybridization.
- Molenaar C, Teuben JM, Heetebrij RJ, Tanke HJ & Reedijk J (2000), New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy, Journal of Biological Inorganic Chemistry 5(5).
- Snaar S, Wiesmeijer K, Jochemsen AG, Tanke HJ & Dirks RW (2000), Mutational analysis of fibrillarin and its mobility in living human cells, Journal of Cell Biology 151(3).
- van de Rijke FM, Florijn RJ, Tanke HJ & Raap AK (2000), DNA fiber-FISH staining mechanism.
- Wiegant JCAG, van Gijlswijk RPM, Heetebrij RJ, Bezrookove V, Raap AK & Tanke HJ (1999), ULS: a versatile method of labeling nucleic acids for FISH based on a monofunctional reaction of cisplatin derivatives with guanine moieties.
- Rosenberg C, Schut TB, Mostert M, Tanke H, Raap A, Oesterhuis JW & Looijenga L (1999), Chromosomal gains and losses in testicular germ cell tumors of adolescents and adults investigated by a modified comparative genomic hybridization approach.
- Lid Raad van Advies
- chief cientific officer
- Professor Medical Delta/ Bionanoscience Group
- co-director
- member advisory board
- Professor bioimaging