Christine Mummery
Hoogleraar Ontwikkelingsbiologie
- Naam
- Prof.dr. C.L. Mummery
- Telefoon
- +31 71 526 9300
- c.l.mummery@lumc.nl
- ORCID iD
- 0000-0002-4549-6535
Christine Mummery is Hoogleraar Ontwikkelingsbiologie in de afdeling Anatomie en Embryolgie en hoofd van de iPSC&OoC Hotel Facility in het LUMC. Van 2015-2023 was zij gasthoogleraar bij de Technische Universiteit Twente om Organ-op-Chip modellen te ontwikkelen. Zij is lid van de KNAW, voormalig bestuurslid van de KNAW en ZonMw, lid van de KHMW en is een laureaat van de European Research Council (Advanced Grant) om hart- ontwikkeling en ziekte te bestuderen m.b.v. humane stamcellen. In het LUMC, is zij co-vz van de Thema RegMedTO en PI in the Novo Nordisk Foundation Stem Cell Center (reNEW), een samenwerking tussen de Universiteit Copenhagen en de Murdoch Children’s Hospital in Melbourne. Zij heeft een aantal prijzen gewonnen oa van de Fondation Lefoulon-Delalande-Institut de France voor onderzoek op cardiovasculair fysiologie (2021) en de Public Service Award (2023) van de International Society of Stem Cell Research (ISSCR). Zij was president van ISSCR 2020-2021. Zij heeft een lekengids over stamcellen geschreven (“Stem Cells: Scientific Facts and Fiction”;Elsevier 2018) en geeft lezingen aan patiëntorganisaties over dit onderwerp. Zij is ook founding editor van Stem Cell Reports, het tijdschrift van de ISSCR en zit in de redactie van o.a. Cell Stem Cell, Circulation Research en Stem Cells. Zij was mede-oprichter en eerste voorzitter van de RvB van de European Organ on Chip Society. Zij is de huidige vz van de RvB van hDMT.
Christine Mummery is Hoogleraar Ontwikkelingsbiologie in de afdeling Anatomie en Embryolgie en hoofd van de iPSC&OoC Hotel Facility in het LUMC. Van 2015-2023 was zij gasthoogleraar bij de Technische Universiteit Twente om Organ-op-Chip modellen te ontwikkelen. Zij is lid van de KNAW, voormalig bestuurslid van de KNAW en ZonMw, lid van de KHMW en is een laureaat van de European Research Council (Advanced Grant) om hart- ontwikkeling en ziekte te bestuderen m.b.v. humane stamcellen. In het LUMC, is zij co-vz van de Thema RegMedTO en PI in the Novo Nordisk Foundation Stem Cell Center (reNEW), een samenwerking tussen de Universiteit Copenhagen en de Murdoch Children’s Hospital in Melbourne. Zij heeft een aantal prijzen gewonnen oa van de Fondation Lefoulon-Delalande-Institut de France voor onderzoek op cardiovasculair fysiologie (2021) en de Public Service Award (2023) van de International Society of Stem Cell Research (ISSCR). Zij was president van ISSCR 2020-2021. Zij heeft een lekengids over stamcellen geschreven (“Stem Cells: Scientific Facts and Fiction”;Elsevier 2018) en geeft lezingen aan patiëntorganisaties over dit onderwerp. Zij is ook founding editor van Stem Cell Reports, het tijdschrift van de ISSCR en zit in de redactie van o.a. Cell Stem Cell, Circulation Research en Stem Cells. Zij was mede-oprichter en eerste voorzitter van de RvB van de European Organ on Chip Society. Zij is de huidige vz van de RvB van hDMT.
Stamcellen en Ontwikkelingsbiologie
Het onderzoeksgebied betreft hart- en bloedvaatontwikkeling en ziektemodellen op basis van humane pluripotente stamcellen. De huidige interessegebied is het toepassen van biofysische technieken in de typering en functionele analyse van cardiovasculaire cellen van hPSC met als uiteindelijke doel, inzicht te krijgen in de onderliggende moleculaire mechanismen van ziekte en de identificatie van mogelijk geneesmiddelen via bioassays. Deze belangstelling komt voort uit een lange fascinatie voor hoe differentiatiekeuzes in ontwikkeling worden gemaakt en welke rol groeifactoren daarin spelen. Na de introductie van hiPSC in het onderzoek door herprogrammering van somatische cellen van patiënten, is duidelijk geworden dat er veel klinische toepassingen mogelijk zijn, vooral in de identificatie van patiënt-specifieke medicijnen en mogelijkheden om ziekteprocessen te behandelen. Naast cardiomyocyten, spelen ook endotheelcellen en gladde spiercellen van bloedvaten een centrale rol in het onderzoek, bijvoorbeeld in een klinisch context waarbij hemorrhaging disease (HHT) veroorzaakt door mutaties in TGFß-receptoren bestudeerd wordt. We hebben een aantal mechanismen van deze ziekte gevonden en onderzoeken nu of medicijnen tegen deze processen ook effectief zijn in patiënten. Door samenwerking met clinici in Leiden en Utrecht en ingenieurs aan UTwente en TU Delft, maken we nu 2D en 3D modellen van ziek- en gezond hart-en bloedvatenweefsel in microfluidische “chips”. Dit studiegebied is een onderdeel van de NWA over personalized medicine, vroege diagnose en regeneratieve geneeskunde.
Current research grants (selectie)
- EU FP7 2013-2017 Plurimes. Mesodermal tissue repair using pluripotent stem cells (450k€).
- CVON (Cardiovascular Onderzoek Nederland) NHS. HUSTCARE 2013-2018. Cardiac repair. Co-PI (350k€).
- European Research Council Advanced Grant 2013-2018. Human pluripotent stem cells: the new heart patient. Personal grant/PI (2.5 M€)
- Muller Foundation (2014-2019). hiPSC models for vascular disease. PI (750k€).
- ERARE-CVD: CPVT heart disease models co-PI (350k€).
- ZonMW MKMD (2017-2020) hIPSC as models for cardiac disease. PI (350k€).
- Interreg: Biomat microfluidic chips (2018-2020). PI. (450k€).
- TK-LSH (2018-2020):hiPSC model of arrhythmia. PI (90k€).
- Ministry of Education, Culture and Science NWO Gravity Grant 2017 (2017-2027) Netherlands Organ on Chip Initiative. PI (18.8 mlj €)
Wetenschappelijke carrière
Christine Mummery is gepromoveerd in de Biofysica bij de Universiteit London. Na haar promotie, begon zij in het Hubrecht Insituut als postdoc, vervolgens staflid en hoogleraar. Na een sabbatical bij de Harvard Stamcel Insituut in 2007, introduceerd zij human geinduceerd pluripotent stamcellen in Nederland. In 2008 was zij benomed tot hoogleraar Ontwikkelings Biologie in het LUMC en werd Afdelings Hoofd Anatomie en Embryologie 2009-2019. In 2015, werd zij gasthoogleraar in de Universiteit Twente, om Organ-op-Chip modellen op te zetten op basis van stamcellen. In 2010, was ze medeoprichter van de LUMC spinout Ncardia bv. Haar huidige onderzoek gaat over modelleren van cardiovasculaire ziektes op basis van patiënt stamcellen en het ontwikkelen van Organ-op-Chip om veiligheid en effectiviteit van (nieuwe) medicijnen te onderzoeken. In 2017, was ze coördinator van een succesvol NWO Zwaartekracht aanvraag en heeft zowel een ERC Advanced beurs als Proof-of-Concept ontvangen. Zij was mede-oprichter van de European Organ on Chip Society (EUROOCS) en het Nederlands Human Organ and Disease Modelling Technology organisation (hDMT). Verder was ze namens hDMT coordinator van een recentelijk NWO GWI, hDMT INFRA StemCells. Zij is lid van de KNAW en KHMW en was ISSCR president 2020-2021. Zij was ook de eerste hoofdredacteur van de de ISSCR tijdschrift Stem Cell Reports.
Zij zit in verschillende wetenschappelijk advies raden oa Hubrecht Institute, Boerhaave Museum, Allen Institute, Mogrify, HeartBeatBio, Agnios, Cellistic, Sync Biosystems en Sartorius Gmbh.
- Promotie Universiteit London: Effect of Ultrasound on Wound Healing
- Oratie LUMC Maart 2009: Stamcellen tussen hype en hypothese
- Oratie Universiteit Twente (Juni 2015): Vessels on Chip
- Oratie Universiteit Utrecht (November 2002): Mending a broken heart
Hoogleraar Ontwikkelingsbiologie
- Faculteit Geneeskunde
- Divisie 4
- Anatomie en Embryologie
- Mummery, C. (2024), Heart and vessels from stem cells, BioEssays.
- Novoa, J.J.; Westra, I.M.; Steeneveld, E.; Neves, N.F.; Arendzen, C.H.; Rajaei, B.; Grundeken, E.; Yildiz, M.; Valk, W. van der; Salvador, A.; Carlotti, F.; Dijkers, P.F.; Locher, H.; Berg, C.W. van den; Raymond, K.I.; Kirkeby, A.; Mummery, C.L.; Rabelink, T.J.; Freund, C.; Meij, P. & Wieles, B. (2024), Good manufacturing practice-compliant human induced pluripotent stem cells, Cytotherapy 26(6): 556-566.
- Nahon, D.M.; Moerkens, R.; Aydogmus, H.; Lendemeijer, B.; Martinez-Silgado, A.; Stein, J.M.; Dostanić, M.; Frimat, J.P.; Gontan, C.; Graaf, M.N.S. de; Hu, M.; Kasi, D.G.; Koch, L.S.; Le, K.T.T.; Lim, S.; Middelkamp, H.H.T.; Mooiweer, J.; Motreuil-Ragot, P.; Niggl, E.; Pleguezuelos-Manzano C.; Puschhof, J.; Revyn, N.; Rivera-Arbelaez, J.M.; Slager, J.; Windt, L.M.; Zakharova, M.; Meer, B.J. van; Orlova, V.V.; Vrij, F.M.S de; Withoff, S.; Mastrangeli, M.; Meer, A.D. van der & Mummery, C.L. (2024), Standardizing designed and emergent quantitative features in microphysiological systems, Nature Biomedical Engineering.
- Juan J. Novoa Inge M. Westra Esther Steeneveld Natascha Fonseca Neves Christiaan H. Arendzen Bahareh Rajaei Esmée Grundeken Mehmet Yildiz Wouter van der Valk Alison Salvador Françoise Carlotti Pascale F. Dijkers Heiko Locher Cathelijne W. van den Berg Karine I. Raymond Agnete Kirkeby Christine L. Mummery Ton J. Rabelink Christian Freund * Pauline Meij ** Brigitte Wieles ** (2024), Good Manufacturing Practice–compliant human induced pluripotent stem cells: from bench to putative clinical products, Cytotherapy.
- Groen, E.; Mummery, C.L.; Yiangou, L. & Davis, R.P. (2024), Three-dimensional cardiac models, Biochemical Society Transactions 52(3).
- Groen, E.; Mummery, C.L.; Yiangou, L. & Davis, R.P. (2024), Three-dimensional cardiac models: a pre-clinical testing platform, Biochemical Society Transactions 52(3): 1045-1059.
- Wiersma, S.; Meraviglia,; Mummery, C.L.; Campostrini, G. & Bellin, M. (2024), The mechanistic role of connexin 43 in maturation of hiPSC cardiomyocytes, Cardiovascular Research 120.
- Blanch-Asensio, A.; Grandela, C.; Mummery, C.L. & Davis, R.P. (2024), STRAIGHT-IN, Nature Protocols.
- Nahon, D.M.; Cuenca, M.V.; Hil, F.E. van den; Hu, M.C.; Korte, T. de; Maagdenberg, A.M.J.M. van den; Mummery, C.L. & Orlova, V.V. (2024), Self-assembling 3D vessel-on-chip model with hiPSC-derived astrocytes, Stem Cell Reports 19(7): 946-956.
- Campostrini, G.; Van-Oostwaard, D.W.; Verkerk, A.; Mummery, C. & Bellin, M. (2024), Maturing hiPSC-cardiomyocytes in cardiac microtissues for accurate preclinical in vitro modelling of long-QT syndrome type 1, Cardiovascular Research 120.
- Arslan, U.; Hil, F.E. van den; Mummery, C.L. & Orlova, V. (2024), Generation and characterization of hiPSC-derived vascularized-, perfusable cardiac microtissues-on-chip, CURRENT PROTOCOLS 4(7).
- Salmenov, R.; Mummery, C. & Huurne, M. ter (2024), Cell cycle visualization tools to study cardiomyocyte proliferation in real-time, Open Biology 14(10).
- Ludwig, T.E.; Andrews, P.W.; Barbaric, I.; Benvenisty, N.; Bhattacharyya, A.; Crook, J.M.; Daheron, L.M.; Draper, J.S.; Healy, L.E.; Huch, M.; Inamdar, M.S.; Jensen, K.B.; Kurtz, A.; Lancaster, M.A.; Liberali, P.; Lutolf, M.P.; Mummery, C.L.; Pera, M.F.; Sato, Y.; Shimasaki, N.; Smith, A.G.; Song, J.; Spits, C.; Stacey, G.; Wells, C.A.; Zhao, T.B. & Mosher, J.T. (2023), ISSCR standards for the use of human stem cells in basic research, Stem Cell Reports 18(9): 1744-1752.
- Nahon, D.M.; Ganesh, S.; Hil, F.E. van den; Freund, C.; Mummery, C.L. & Orlova, V.V. (2023), Genetic repair of a human induced pluripotent cell line from patient with Dutch-type cerebral amyloid angiopathy, Stem Cell Research 71.
- Rivron, N.C.; Martinez-Arias, A.; Sermon, K.; Mummery, C.; Schöler, H.R.; Wells, J.; Nichols, J.; Hadjantonakis, A.K.; Lancaster, M.A.; Morris, N.; Fu, J.P.; Sturmey, R.G.; Niakan, K.; Rossant, J. & Kato, K. (2023), Changing the public perception of human embryology, Nature Cell Biology.
- Mummery, C. (2023), Getting to the heart of stem cell research: an interview with Christine Mummery, Disease Models and Mechanisms 16(5).
- Windt, L.M.; Wiendels, M.; Dostanic, M.; Bellin, M.; Sarro, P.M.; Mastrangeli, M.; Mummery, C.L. & Meer, B.J. van (2023), Miniaturized engineered heart tissues from hiPSC-derived triple cell type co-cultures to study human cardiac function, Biochemical and Biophysical Research Communications 681: 200-211.
- Tsui, H.; Kampen, S.J. van; Han, S.J.; Meraviglia, V.; Ham, W. van; Vink, A.; Yin, X.; Mayr, M.; Bezstarosti, K.; Demmers, J.A.A.; Mummery, C.L.; Veen, T.A.B. van; Remme, C.A.; Bellin, M. & Rooij, E. van (2023), Desmosomal degradation as an underlying cause for arrhythmogenic cardiomyopathy, European Journal of Heart Failure 25: 28-28.
- Arendzen, C.H.; Cramer, S.J.; Freund, C.M.A.H.; Mummery, C.L.; Ranga, A. & Mikkers, H.M.M. (2023), Introduction of a Geminin mScarlet reporter into H2B-mTurq2 hiPSCs for live-cell imaging of proliferation and cell cycling, Stem Cell Research 67.
- Shoji, J.Y.; Davis, R.P.; Mummery, C.L. & Krauss, S. (2023), Global meta-analysis of organoid and organ-on-chip research, Advanced Healthcare Materials.
- Gabbin, B.; Meraviglia, V.; Angenent, M.L.; Ward-van Oostwaard, D.; Sol, W.; Mummery, C.L.; Rabelink, T.J.; Meer, B.J. van; Berg, C.W. van den & Bellin, M. (2023), Heart and kidney organoids maintain organ-specific function in a microfluidic system, Materials Today Bio 23.
- Nguyen, P.D.; Gooijers, I.; Campostrini, G.; Verkerk, A.O.; Honkoop, H.; Bouwman, M.; Bakker, D.E.M. de; Koopmans, T.; Vink, A.; Lamers, G.E.M.; Shakked, A.; Mars, J.; Mulder, A.A.; Chocron, S.; Bartscherer, K.; Tzahor, E.; Mummery, C.L.; Boer, T.P. de; Bellin, M. & Bakkers, J. (2023), Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration, Science 380(6646): 758-764.
- Ottaviani, D.; Huurne, M. ter; Elliott, D.A.; Bellin, M. & Mummery, C.L. (2023), Maturing differentiated human pluripotent stem cells in vitro: methods and challenges, Development 150(11).
- Jordan, R.; Ford-Scheimer, S.L.; Alarcon, R.M.; Atala, A.; Borenstein, J.T.; Brimacombe, K.R.; Cherry, S.; Clevers, H.; Davis, M.; Funnell, S.G.P.; Gehrke, L.; Griffith, L.G.; Grossman, A.C.; Hartung, T.; Ingber, D.E.; Kleinstreuer, N.C.; Kuo, C.J.; Lee, E.M.; Mummery, C.L.; Pickett, T.E.; Ramani, S.; Rosado-Olivieri, E.A.; Struble, E.B.; Wan, Z.P.; Williams, M.S.; Hall, M.D.; Ferrer, M. & Markossian, S. (2023), Report of the Assay Guidance Workshop on 3-dimensional tissue models for antiviral drug development, The Journal of Infectious Diseases 228: S337-S354.
- Arslan, U.; Brescia, M.; Meraviglia, V.; Nahon, D.M.; Helden, R.W.J. van; Stein, J.M.; Hil, F.E. van den; Meer, B.J. van; Cuenca, M.V.; Mummery, C.L. & Orlova, V.V. (2023), Vascularized hiPSC-derived 3D cardiac microtissue on chip, Stem Cell Reports 18(7): 1394-1404.
- Montilla-Rojo, J.; Bialecka, M.; Wever, K.E.; Mummery, C.L.; Looijenga, L.H.J.; Roelen, B.A.J. & Salvatori, D.C.F. (2023), Teratoma assay for testing pluripotency and malignancy of stem cells: insufficient reporting and uptake of animal-free methods - a systematic review, International Journal of Molecular Sciences 24(4).
- Blanch-Asensio, A.; Vaart, B. van der; Vinagre, M.; Groen, E.; Arendzen, C.; Freund, C.; Geijsen, N.; Mummery, C.L. & Davis, R.P. (2023), Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads, Stem Cell Research 66.
- (2022), Three-Dimensional Vessels-on-a-Chip Based on hiPSC-derived Vascular Endothelial and Smooth Muscle Cells, Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.].
- Bulut, M.; Cuenca, M.V.; Graaf, M. de; Hil, F.E. van den; Mummery, C.L. & Orlova, V.V. (2022), Three-dimensional vessels-on-a-chip based on hiPSC-derived vascular endothelial and smooth muscle cells, CURRENT PROTOCOLS 2(10).
- Stein, J.M.; Arslan, U.; Franken, M.; Greef, J.C. de; Harding, S.E.; Mohammadi, N.; Orlova, V.V.; Bellin, M.; Mummery, C.L. & Meer, B.J. van (2022), Software tool for automatic quantification of sarcomere length and organization in fixed and live 2D and 3D muscle cell cultures in vitro, CURRENT PROTOCOLS 2(7).
- Fibbe, W.; Bernardi, R.; Charbord, P.; Krause, D.; Celso, C. lo; Mendez-Ferrer, S.; Mummery, C.; Oostendorp, R.; Raaijmakers, M.; Socie, G.; Staal, F. & Bacigalupo, A. (2022), The EHA Research Roadmap: Hematopoietic Stem Cells and Allotransplantation, HemaSphere 6(5).
- Kasi, D.G.; Graaf, M.N.S. de; Motreuil-Ragot, P.A.; Frimat, J.P.M.S.; Ferrari, M.D.; Sarro, P.M.; Mastrangeli, M.; Maagdenberg, A.M.J.M. van den; Mummery, C.L. & Orlova, V.V. (2022), Rapid prototyping of organ-on-a-chip devices using maskless photolithography, Micromachines 13(1).
- Graaf, M.N.S. de; Vivas, A.; Meer, A.D. van der; Mummery, C.L. & Orlova, V.V. (2022), Pressure-driven perfusion system to control, multiplex, and recirculate cell culture medium for organs-on-chips, Micromachines 13(8).
- Ramovs, V.; Janssen, H.; Fuentes, I.; Pitaval, A.; Rachidi, W.; Lopes, S.M.C.D.; Freund, C.; Gidrol, X.; Mummery, C. & Raymond, K. (2022), hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction, Journal of Investigative Dermatology 142(12): S278-S278.
- Arslan, U.; Orlova, V.V. & Mummery, C.L. (2022), Perspectives for future use of cardiac microtissues from human pluripotent stem cells, ACS Biomaterials Science and Engineering 8(11).
- Arslan, U.; Moruzzi, A.; Nowacka, J.; Mummery, C.L.; Eckardt, D.; Loskill, P. & Orlova, V.V. (2022), Microphysiological stem cell models of the human heart, Materials Today Bio 14.
- Zon, L.; Keller, G.; Daley, G.Q.; Watt, F.M.; Weissman, I.L.; Fuchs, E.; Gage, F.H.; Yamanaka, S.; Rossant, J.; Morrison, S.; Temple, S.; Clevers, H.C.; Srivastava, D.; Mummery, C.L. & Little, M. (2022), ISSCR Presidents look back on their presidency, the evolution of the field, and the Society, Stem Cell Reports 17(6): 1237-1244.
- Cable, J.; Arlotta, P.; Parker, K.K.; Hughes, A.J.; Goodwin, K.; Mummery, C.L.; Kamm, R.D.; Engle, S.J.; Tagle, D.A.; Boj, S.F.; Stanton, A.E.; Morishita, Y.; Kemp, M.L.; Norfleet, D.A.; May, E.E.; Lu, A.; Bashir, R.; Feinberg, A.W.; Hull, S.M.; Gonzalez, A.L.; Blatchley, M.R.; Pulido, N.M.; Morizane, R.; McDevitt, T.C.; Mishra, D. & Mulero-Russe, A. (2022), Engineering multicellular living systems, Annals of the New York Academy of Sciences 1518(1): 183-195.
- Hessels, J.; Kroon, S.; Boerman, S.; Nelissen, R.C.; Grutters, J.C.; Snijder, R.J.; Lebrin, F.; Post, M.C.; Mummery, C.L. & Mager, J.J. (2022), Efficacy and safety of tacrolimus as treatment for bleeding caused by hereditary hemorrhagic telangiectasia, Journal of Clinical Medicine 11(18).
- Ruiz, A.R.; Hoolwerff, M. van; Sprangers, S.; Suchiman, E.; Schoenmaker, T.; Dibbets-Schneider, P.; Bloem, J.L.; Nelissen, R.G.H.H.; Freund, C.; Mummery, C.; Everts, V.; Vries, T.J. de; Ramos, Y.F.M. & Meulenbelt, I. (2022), Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization, Rheumatology 62(1).
- Pistollato, F.; Bal-Price, A.; Coecke, S.; Parvatam, S.; Pamies, D.; Czysz, K.; Hao, J.; Kee, K.; Teo, A.K.K.; Niu, S.S.; Wilmes, A.; Smirnova, L.; Freund, C.; Mummery, C. & Stacey, G. (2022), Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells, Reproductive Toxicology 112: 36-50.
- Orlova, V.V.; Nahon, D.M.; Cochrane, A.; Cao, X.; Freund, C.; Hil, F. van den; Westermann, C.J.J.; Snijder, R.J.; Amstel, J.K.P. van; Dijke, P. ten; Lebrin, F.; Mager, H.J. & Mummery, C.L. (2022), Vascular defects associated with hereditary hemorrhagic telangiectasia revealed in patient-derived isogenic iPSCs in 3D vessels on chip, Stem Cell Reports 17(7): 1536-1545.
- Yiangou, L.; Blanch-Asensio, A.; Korte, T. de; Miller, D.C.; Meer, B.J. van; Mol, M.P.H.; Brink, L. van den; Brandao, K.O.; Mummery, C.L. & Davis, R.P. (2022), Optogenetic reporters delivered as mRNA facilitate repeatable action potential and calcium handling assessment in human iPSC-derived cardiomyocytes, Stem Cells 40(7).
- Graaf, M.N.S. de; Vivas, A.; Kasi, D.G.; Hil, F.E. van den; Berg, A. van den; Meer, A.D. van der; Mummery, C.L. & Orlova, V.V. (2022), Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip, Lab on a Chip 23(1): 168-181.
- Campostrini, G.; Ward-Van Oostwaard, D.; Kosmidis, G.; Verkerk, A.O.; Bezzina, C.R.; Mummery, C.L. & Bellin, M. (2022), Maturation of hiPSC-derived cardiomyocytes in cardiac microtissues promotes adult alternative splicing of sodium channel revealing mutation effects associated with cardiac arrhythmia, Cardiovascular Research 118(SUPPL 1).
- Campostrini, G.; Kosmidis, G.; Ward-van Oostwaard, D.; Davis, R.P.; Yiangou, L.; Ottaviani, D.; Veerman, C.C.; Mei, H.L.; Orlova, V.V.; Wilde, A.A.M.; Bezzina, C.R.; Verkerk, A.O.; Mummery, C.L. & Bellin, M. (2022), Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia, Cardiovascular Research.
- Gabbin, B.; Meraviglia, V.; Mummery, C.L.; Rabelink, T.J.; Meer, B.J. van; Berg, C.W. van den & Bellin, M. (2022), Toward Human Models of Cardiorenal Syndrome in vitro, Frontiers in Cardiovascular Medicine 9.
- Blanch-Asensio, A.; Grandela, C.; Brandao, K.O.; Korte, T. de; Mei, H.L.; Ariyurek, Y.; Yiangou, L.; Mol, M.P.H.; Meer, B.J. van; Kloet, S.L.; Mummery, C.L. & Davis, R.P. (2022), STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells, Cell Reports: Methods 2(10).
- Cao, X.; Mircea, M.; Yakala, G.K.; Hil, F.E. van den; Brescia, M.; Mei, H.L.; Mummery, C.L.; Semrau, S. & Orlova, V.V. (2022), ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation, Stem Cells 41(2).
- Fuchs, S.; Helden, R.W.J. van; Wiendels, M.; Graaf, M.N.S. de; Orlova, V.V.; Mummery, C.L.; Meer, B.J. van & Mayr, T. (2022), On-chip analysis of glycolysis and mitochondrial respiration in human induced pluripotent stem cells, Materials Today Bio 17.
- Ramovs, V.; Janssen, H.; Fuentes, I.; Pitaval, A.; Rachidi, W.; Lopes, S.M.C.D.; Freund, C.; Gidrol, X.; Mummery, C.L. & Raymond, K. (2022), Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids, Stem Cell Reports 17(6): 1279-1288.
- Mummery, C. & Anthony, E. (2021), New guidelines for embryo and stem cell research, Nature Reviews Molecular Cell Biology 22(12): 773-774.
- Ramovs, V.; Fuentes, I.; Freund, C.; Mikkers, H.; Mummery, C.L. & Raymond, K. (2021), Generation and genetic repair of two human induced pluripotent cell lines from patients with Epidermolysis Bullosa simplex and dilated cardiomyopathy associated with a heterozygous mutation in the translation initiation codon of KLHL24, Stem Cell Research 57.
- Stein, J.M.; Mummery, C.L. & Bellin, M. (2021), Engineered models of the human heart: Directions and challenges, Stem Cell Reports 16(9): 2049-2057.
- Pei, J.; Schuldt, M.; Nagyova, E.; Gu, Z.; Bouhaddani, S. el; Yiangou, L.; Jansen, M.; Calis, J.J.A.; Dorsch, L.M.; Blok, C.S.; Dungen, N.A.M. van den; Lansu, N.; Boukens, B.J.; Efimov, I.R.; Michels, M.; Verhaar, M.C.; Weger, R. de; Vink, A.; Steenbeek, F.G. van; Baas, A.F.; Davis, R.P.; Uh, H.W.; Kuster, D.W.D.; Cheng, C.; Mokry, M.; Velden, J. van der; Asselbergs, F.W. & Harakalova, M. (2021), Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations, Clinical Epigenetics 13(1).
- Yiangou, L.; Davis, R.P. & Mummery, C.L. (2021), Using cardiovascular cells from human pluripotent stem cells for COVID-19 research, Stem Cell Reports 16(3): 385-397.
- Karina O. Brandão, Catarina Grandela, Loukia Yiangou, Christine L. Mummery & Richard P. Davis (2021), CRISPR/Cas9-Mediated Introduction of Specific Heterozygous Mutations in Human Induced Pluripotent Stem Cells., Methods in Molecular Biology.
- Arendzen, C.H.; Chaudhari, U.; Cramer, S.J.; Freund, C.M.A.H.; Mummery, C.L.; Ranga, A.; Pourquie, O. & Mikkers, H.M.M. (2021), Generation of LUMCi041-A-2, Stem Cell Research 57.
- Ruiz, A.R.; Hoolwerff, M. van; , A. das; Ciere, L.C.; Tuerlings, M.; Orlova, V.; Suchiman, H.; Freund, C.M.; Mummery, C.; Meulenbelt, I. & Ramos, Y.F. (2021), UNRAVELLING THE ROLE OF OSTEOPROTEGERIN IN OSTEOARTHRITIS BY APPLYING A HUMAN ISOGENIC INDUCED PLURIPOTENT STEM CELL MODEL, Osteoarthritis and Cartilage 29: S409-S409.
- Galaris, G.; Montagne, K.; Thalgott, J.H.; Goujon, G.J.P.E.; Driesche, S. van den; Martin, S.; Mager, H.J.J.; Mummery, C.L.; Rabelink, T.J. & Lebrin, F. (2021), Thresholds of ENDOGLIN expression in endothelial cells explains vascular etiology in Hereditary Hemorrhagic Telangiectasia type 1, International Journal of Molecular Sciences 22(16).
- Veldhoven, J.P.D. van; Campostrini, G.; Gessel, C.J.E. van; Ward-van Oostwaard, D.; Liu, R.F.; Mummery, C.L.; Bellin, M. & IJzerman, A.P. (2021), Targeting the K(v)11.1 (hERG) channel with allosteric modulators, European Journal of Medicinal Chemistry 212.
- Mummery, C.; Little, M.; Lin, H.F.; Clark, A.; Zaret, K.; Srivastava, D.; Fuchs, E.; Watt, F.; Temple, S. & ISSCR Board 2020-2021 (2021), Mentorship in science: response to AlShebli et al., Nature Communications 2020, Stem Cell Reports 16(1): 1-2.
- Hoolwerff, M. van; Ruiz, A.R.; Suchiman, E.; Bouma, M.J.; Freund, C.M.; Mummery, C.L.; Ramos, Y.F. & Meulenbelt, I. (2021), HIGH IMPACT MUTATION FN1 AFFECTS CARTILAGE INTEGRITY VIA ABERRANT BINDING TO COLLAGEN TYPE II, Osteoarthritis and Cartilage 29: S405-S406.
- Orlova, V.V. & Mummery, C.L. (2021), Heart defects recapitulated in human cardioids, Cell Research 31(9): 947-948.
- Helden, R.W.J. van; Birket, M.J.; Freund, C.; Arendzen, C.H.; Mikkers, H.M.; Orlova, V.; Coo, R.I. de; Mummery, C.L. & Bellin, M. (2021), Generation of three human induced pluripotent stem cell lines, LUMCi024-A, LUMCi025-A, and LUMCi026-A, from two patients with combined oxidative phosphorylation deficiency 8 and a related control, Stem Cell Research 53.
- Campostrini, G.; Meraviglia, V.; Giacomelli, E.; Helden, R.W.J. van; Yiangou, L.; Davis, R.P.; Bellin, M.; Orlova, V.V. & Mummery, C.L. (2021), Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells, Nature Protocols 16(4): 2213-+.
- Abou-el-Enein, M.; Angelis, A.; Appelbaum, F.R.; Andrews, N.C.; Bates, S.E.; Bierman, A.S.; Brenner, M.K.; Cavazzana, M.; Caligiuri, M.A.; Clevers, H.; Cooke, E.; Daley, G.Q.; Dzau, V.J.; Ellis, L.M.; Fineberg, H.V.; Goldstein, L.S.B.; Gottschalk, S.; Hamburg, M.A.; Ingber, D.E.; Kohn, D.B.; Krainer, A.R.; Maus, M.V.; Marks, P.; Mummery, C.L.; Pettigrew, R.I.; Rutter, J.L.; Teichmann, S.A.; Terzic, A.; Urnov, F.D.; Williams, D.A.; Wolchok, J.D.; Lawler, M.; Turtle, C.J.; Bauer, G. & Ioannidis, J.P.A. (2021), Evidence generation and reproducibility in cell and gene therapy research: a call to action, Molecular Therapy - Methods and Clinical Development 22.
- Cuenca, M.V.; Cochrane, A.; Hil, F.E. van den; Vries, A.A.F. de; Oberstein, S.A.J.L.; Mummery, C.L. & Orlova, V.V. (2021), Engineered 3D vessel-on-chip using hiPSC-derived endothelial- and vascular smooth muscle cells, Stem Cell Reports 16(9): 2159-2168.
- Ruiz, A.R.; Dicks, A.; Tuerlings, M.; Schepers, K.; Pel, M. van; Nelissen, R.G.H.H.; Freund, C.; Mummery, C.L.; Orlova, V.; Guilak, F.; Meulenbelt, I. & Ramos, Y.F.M. (2021), Cartilage from human-induced pluripotent stem cells, Cell and Tissue Research 386.
- Campostrini, G.; Windt, L.M.; Meer, B.J. van; Bellin, M. & Mummery, C.L. (2021), Cardiac tissues from stem cells new routes to maturation and cardiac regeneration, Circulation Research 128(6): 775-801.
- Brink, L. van den; Brandao, K.O.; Yiangou, L.; Blanch-Asensio, A.; Mol, M.P.H.; Mummery, C.L.; Verkerk, A.O. & Davis, R.P. (2021), The linkage phase of the polymorphism KCNH2-K897T influences the electrophysiological phenotype in hiPSC models of LQT2, Frontiers in Physiology 12.
- Brandao, K.O.; Brink, L. van den; Miller, D.C.; Grandela, C.; Meer, B.J. van; Mol, M.P.H.; Korte, T. de; Tertoolen, L.G.J.; Mummery, C.L.; Sala, L.; Verkerk, A.O. & Davis, R.P. (2020), Isogenic sets of hiPSC-CMs harboring distinct KCNH2 mutations differ functionally and in susceptibility to drug-induced arrhythmias, Stem Cell Reports 15(5).
- Giacomelli, E.; Meraviglia, V.; Campostrini, G.; Cochrane, A.; Cao, X.; Helden, R.W.J. van; Garcia, A.K.; Mircea, M.; Kostidis, S.; Davis, R.P.; Meer, B.J. van; Jost, C.R.; Koster, A.J.; Mei, H.L.; Miguez, D.G.; Mulder, A.A.; Ledesma-Terron, M.; Pompilio, G.; Sala, L.; Salvatori, D.C.F.; Slieker, R.C.; Sommariva, E.; Vries, A.A.F. de; Giera, M.; Semrau, S.; Tertoolen, L.G.J.; Orlova, V.V.; Bellin, M. & Mummery, C.L. (2020), Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease, Cell Stem Cell 26(6): 862-+.
- Bouma, M.J.; Orlova, V.; Hil, F.E. van den; Mager, H.J.; Baas, F.; Knijff, P. de; Mummery, C.L.; Mikkers, H. & Freund, C. (2020), Generation and genetic repair of 2 iPSC clones from a patient bearing a heterozygous c.1120del18 mutation in the ACVRL1 gene leading to Hereditary Hemorrhagic Telangiectasia (HHT) type 2, Stem Cell Research 46.
- Meraviglia, V.; Arendzen, C.H.; Freund, C.; Atsma, D.E.; Mummery, C.L. & Bellin, M. (2020), Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene, Stem Cell Research 45.
- Qiao, X.H.; Zanden, S.Y. van der; Wander, D.P.A.; Borras, D.M.; Song, J.Y.; Li, X.Y.; Duikeren, S. van; Gils, N. van; Rutten, A.; Herwaarden, T. van; Tellingen, O. van; Giacomelli, E.; Bellin, M.; Orlova, V.; Tertoolen, L.G.J.; Gerhardt, S.; Akkermans, J.J.; Bakker, J.M.; Zuur, C.L.; Pang, B.X.; Smits, A.M.; Mummery, C.L.; Smit, L.; Arens, R.; Li, J.M.; Overkleeft, H.S. & Neefjes, J. (2020), Uncoupling DNA damage from chromatin damage to detoxify doxorubicin, Proceedings of the National Academy of Sciences 117(26): 15182-15192.
- Low, L.A.; Mummery, C.; Berridge, B.R.; Austin, C.P. & Tagle, D.A. (2020), Organs-on-chips, Nature Reviews Drug Discovery 20.
- Stein, J.M.; Mummery, C.L. & Bellin, M. (2020), Engineered models of the human heart: directions and challenges, Stem Cell Reports 16(9).
- Korte, T. de; Katili, P.A.; Yusof, N.A.N.M.; Meer, B.J. van; Saleem, U.; Burton, F.L.; Smith, G.L.; Clements, P.; Mummery, C.L.; Eschenhagen, T.; Hansen, A.; Denning, C. & Insel, P.A. (2020), Unlocking personalized biomedicine and drug discovery with human induced pluripotent stem cell-derived cardiomyocytes, Annual Review of Pharmacology and Toxicology 60: 529-551.
- Cao, X.; Hil, F.E. van den; Mummery, C.L. & Orlova, V. (2020), Generation and functional characterization of monocytes and macrophages derived from human induced pluripotent stem cells, Current Protocols in Stem Cell Biology 52.
- Tang, H.Q.; Abouleila, Y.; Si, L.L.; Ortega-Prieto, A.M.; Mummery, C.L.; Ingber, D.E. & Mashaghi, A. (2020), Human organs-on-chips for virology, Trends in Microbiology 28(11): 934-946.
- Mummery, C. (2020), Scientific collaboration and communication in the time of COVID-19: a chat with Christine Mummery, Cell Stem Cell 27(6): 856-858.
- Dostanic, M.; Windt, L.M.; Stein, J.M.; Meer, B.J. van; Bellin, M.; Orlova, V.; Mastrangeli, M.; Mummery, C.L. & Sarro, P.M. (2020), A miniaturized EHT platform for accurate measurements of tissue contractile properties, Journal of Microelectromechanical Systems 29(5): 881-887.
- Ribeiro, M.C.; Slaats, R.H.; Schwach, V.; Rivera-Arbelaez, J.M.; Tertoolen, L.G.J.; Meer, B.J. van; Molenaar, R.; Mummery, C.L.; Claessens, M.M.A.E. & Passier, R. (2020), A cardiomyocyte show of force, Journal of Molecular and Cellular Cardiology 141: 54-64.
- Brink, L. van den; Grandela, C.; Mummery, C.L. & Davis, R.P. (2020), Inherited cardiac diseases, pluripotent stem cells and genome editing combined – the past, present and future, Stem Cells 38(2).
- Brink, L. van den; Brandao, K.O.; Yiangou, L.; Mol, M.P.H.; Grandela, C.; Mummery, C.L.; Verkerk, A.O. & Davis, R.P. (2020), Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties, Stem Cell Research 43.
- Saleem, U.; Meer, B.J. van; Katili, P.A.; Yusof, N.A.N.M.; Mannhardt, I.; Garcia, A.K.; Tertoolen, L.; Korte, T. de; Vlaming, M.L.H.; McGlynn, K.; Nebel, J.; Bahinski, A.; Harris, K.; Rossman, E.; Xu, X.P.; Burton, F.L.; Smith, G.L.; Clements, P.; Mummery, C.L.; Eschenhagen, T.; Hansen, A. & Denning, C. (2020), Blinded, multicenter evaluation of drug-induced changes in contractility using human-induced pluripotent stem cell-derived cardiomyocytes, Toxicological Sciences 176(1): 103-123.
- Schwach, V.; Fernandes, M.G.; Maas, S.; Gerhardt, S.; Tsonaka, R.; Weerd, L. van der; Passier, R.; Mummery, C.L.; Birket, M.J. & Salvatori, D.C.F. (2020), Expandable human cardiovascular progenitors from stem cells for regenerating mouse heart after myocardial infarction, Cardiovascular Research 116(3): 545-553.
- Iendaltseva, O.; Orlova, V.V.; Mummery, C.L.; Danen, E.H.J. & Schmidt, T. (2020), Fibronectin patches as anchoring points for force sensing and transmission in human induced pluripotent stem cell-derived pericytes, Stem Cell Reports 14(6): 1107-1122.
- Mannhardt, I.; Saleem, U.; Mosqueira, D.; Loos, M.F.; Ulmer, B.M.; Lemoine, M.D.; Larsson, C.; Ameen, C.; Korte, T. de; Vlaming, M.L.H.; Harris, K.; Clements, P.; Denning, C.; Hansen, A. & Eschenhagen, T. (2020), Comparison of 10 control hPSC lines for drug screening in an engineered heart tissue format, Stem Cell Reports 15(4): 983-998.
- Altrocchi, C.; Korte, T. de; Bernardi, J.; Spatjens, R.L.H.M.G.; Braam, S.R.; Heijman, J.; Zaza, A. & Volders, P.G.A. (2020), Repolarization instability and arrhythmia by I-Kr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers, EP Europace 22(9): 1431-1441.
- IJzendoorn, D.G.P. van; Salvatori, D.C.F.; Cao, X.; Hil, F. van den; Briaire-de Bruijn, I.H.; Jong, D. de; Mei, H.L.; Mummery, C.L.; Szuhai, K.; Bovee, J.V.M.G. & Orlova, V.V. (2020), Vascular tumor recapitulated in endothelial cells from hiPSCs engineered to express the SERPINE1-FOSB translocation, Cell Reports Medicine 1(9).
- Riet, S. van; Ninaber, D.K.; Mikkers, H.M.M.; Tetley, T.D.; Jost, C.R.; Mulder, A.A.; Pasman, T.; Baptista, D.; Poot, A.A.; Truckenmuller, R.; Mummery, C.L.; Freund, C.; Rottier, R.J. & Hiemstra, P.S. (2020), In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells, Scientific Reports 10(1).
- Berg, A. van den; Mummery, C.L.; Passier, R. & Meer, A.D. van der (2019), Personalised organs-on-chips, Lab on a Chip 19(2): 198-205.
- Mastrangeli, M.; Millet, S.; Mummery, C.; Loskill, P.; Braeken, D.; Eberle, W.; Cipriano, M.; Fernandez, L.; Graef, M.; Gidrol, X.; Picollet-D'Hahan, N.; Meer, B. van; Ochoa, I.; Schutte, M. & Einden-van Raaij, J. van den (2019), Building Blocks for a European Organ-on-Chip Roadmap, ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION 36(3): 481-492.
- Divolis, G.; Stavropoulos, A.; Manioudaki, M.; Apostolidou, A.; Doulou, A.; Gavriil, A.; Dafnis, I.; Chroni, A.; Mummery, C.; Xilouri, M. & Sideras, P. (2019), Activation of both transforming growth factor-β and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia, Brain Communications 1(1).
- Brink, L. van den; Grandela, C.; Mummery, C.L. & Davis, R.P. (2019), Concise review: Inherited cardiac diseases, pluripotent stem cells, and genome editing combined-the past, present, and future, STEM CELLS.
- Campostrini, G.; Sala, L.; Ward-van Oostwaard, D.; Meer, B. van; Tertoolen, L.G.J.; Bartulos-Encinas, O.; Braam, S.R.; IJzerman, A.P.; Mummery, C.L. & Bellin, M. (2019), A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes, Acta Physiologica 227: 159-160.
- Cao, X.; Yakala, G.K.; Hil, F.E. van den; Cochrane, A.; Mummery, C.L. & Orlova, V.V. (2019), Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives, Stem Cell Reports 12(6): 1282-1297.
- Bouma, M.J.; Freund, C.; IJzerman, A.P.; Boomsma, D.I.; Mummery, C.L. & Raymond, K. (2019), Lymphoblast-derived hiPS cell lines generated from four individuals of a family of genetically unrelated parents and their female monozygotic twins, Stem Cell Research 41.
- Tiemeier, G.L.; Wang, G.Q.; Dumas, S.J.; Sol, W.M.P.J.; Avramut, M.C.; Karakach, T.; Orlova, V.V.; Berg, C.W. van den; Mummery, C.L.; Carmeliet, P.; Berg, B.M. van den & Rabelink, T.J. (2019), Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation, Stem Cell Reports 13(5): 803-816.
- Mummery C (2019), Cardiovascular diseases and drugs: where are we with hiPSC models?, FEBS Open Bio 9: 4-4.
- Mummery, C.; Bellin, M.; Giacomelli, E.; Meer, V. van; Orlova, V.; Sala, L. & Tertoolen, L. (2019), Cardiovascular diseases and drugs: where are we with hiPSC models?, Acta Physiologica 227: 17-17.
- Graaf, M.N.S. de; Cochrane, A.; Hil, F.E. van den; Buijsman, W.; Meer, A.D. van der; Berg, A. van den; Mummery, C.L. & Orlova, V.V. (2019), Scalable microphysiological system to model three-dimensional blood vessels, APL Bioengineering 3.
- de Korte T, van Meer B, Garcia AK, Tertoolen L, Clements PJ, Bahinski A, Rossman EI, Xu XP, Turner S, Denning C, Vlaming M, Braam S & Mummery C (2019), Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions, Journal of Pharmacological and Toxicological Methods 99.
- Meer, B.J. van; Krotenberg, A.; Sala, L.; Davis, R.P.; Eschenhagen, T.; Denning, C.; Tertoolen, L.G.J. & Mummery, C.L. (2019), Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes, Nature Communications 10.
- Cao, X.; Yakala, G.K.; Hil, F.E. van den; Cochrane, A.; Mummery, C.L. & Orlova, V.V. (2019), Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives, Stem Cell Reports 12.
- Pollenus, T.; Martin, S.; Bracquart, D.; Mager, J.; Mummery, C.L. & Lebrin, F. (2019), A threshold of endoglin expression in endothelial cells explains the vascular etiology of hereditary hemorrhagic telangiectasia, Angiogenesis 22(4): 592-592.
- Thalgott, J.; Dos-Santos-Luis, D.; Hosman, A.; Martin, S.; Lamande, N.; Bracquart, D.; Srun, S.; Galaris, G.; Boer, H. de; Tual-Chalot, S.; Kroon, S.; Arthur, H.; Cao, Y.; Snijder, R.; Disch, F.; Mager, J.; Rabelink, T.; Mummery, C.; Raymond, K. & Lebrin, F. (2019), Decreased expression of VEGFR1 contributes to the pathogenesis of hereditary hemorrhagic telangiectasia type 2, Angiogenesis 22(4): 600-600.
- Cochrane, A.; Albers, H.J.; Passier, R.; Mummery, C.L.; Berg, A. van den; Orlova, V.V. & Meer, A.D. van der (2019), Advanced in vitro models of vascular biology: human induced pluripotent stem cells and organ-on-chip technology, Advanced Drug Delivery Reviews 140: 68-77.
- Halaidych, O.V.; Mummery, C.L. & Orlova, V.V. (2019), Quantifying Ca2+ signaling and contraction in vascular pericytes and smooth muscle cells, Biochemical and Biophysical Research Communications 513(1): 112-118.
- Halaidych, O.V.; Cochrane, A.; Hil, F.E. van den; Mummery, C.L. & Orlova, V.V. (2019), Quantitative analysis of intracellular Ca2+ release and contraction in hiPSC-derived vascular smooth muscle cells, Stem Cell Reports 12(4): 647-656.
- Graaf, M.N.S. de; Cochrane, A.; Hil, F.E. van den; Buijsman, W.; Meer, A.D. van der; Berg, A. van den; Mummery, C.L. & Orlova, V.V. (2019), Scalable microphysiological system to model three-dimensional blood vessels, APL BIOENGINEERING 3(2).
- Zwartsen, A.; Korte, T. de; Nacken, P.; Lange, D.W. de; Westerink, R.H.S. & Hondebrink, L. (2019), Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings, Journal of Molecular and Cellular Cardiology 136: 102-112.
- Pugsley, M.K.; Korte, T. de; Udupa, V.; Authier, S. & Curtis, M.J. (2019), Methodological and technological advances in safety pharmacology - New or simply nuanced?, Journal of Pharmacological and Toxicological Methods 99.
- Orlova, V.V.; Cao, X.; Freund, C.; Sanchez-Duffhues, G.; Hawinkels, L.; Petrus-Reurer, S.; Hil, F.E. van den; Disch, F.; Snijder, R.J.; Westermann, C.J.J.; Mager, J.J.; Dijke, P. ten; Amstel, J.K.P. van & Mummery, C.L. (2018), Isogenic induced pluripotent stem cells (IPSCS) derived from mosaic hereditary hemorrhagic telangiectasia type 1 (HHT1) patient, Angiogenesis 21(1): 129-129.
- Andrejecsk, J.W.; Hosman, A.E.; Botella, L.M.; Shovlin, C.L.; Arthur, H.M.; Dupuis-Girod, S.; Buscarini, E.; Hughes, C.C.W.; Lebrin, F.; Mummery, C.L.; Post, M.C. & Mager, J.J. (2018), Executive summary of the 12th HHT international scientific conference, Angiogenesis 21(1): 169-181.
- Anderson, D.J.; Kaplan, D.I.; Bell, K.M.; Koutsis, K.; Haynes, J.M.; Mills, R.J.; Phelan, D.G.; Qian, E.L.; Leitoguinho, A.R.; Arasaratnam, D.; Labonne, T.; Ng, E.S.; Davis, R.P.; Casini, S.; Passier, R.; Hudson, J.E.; Porrello, E.R.; Costa, M.W.; Rafii, A.; Curl, C.L.; Delbridge, L.M.; Harvey, R.P.; Oshlack, A.; Cheung, M.M.; Mummery, C.L.; Petrou, S.; Elefanty, A.G.; Stanley, E.G. & Elliott, D.A. (2018), NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network, Nature Communications 9.
- Mummery, C.L. (2018), Perspectives on the Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Biomedical Research, Stem Cell Reports 11(6): 1306-1311.
- Tong, C.Q.; Liu, T.X.; Talens, V.S.; Noteborn, W.E.M.; Sharp, T.H.; Hendrix, M.M.R.M.; Voets, I.K.; Mummery, C.L.; Orlova, V.V. & Kieltyka, R.E. (2018), Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives, Biomacromolecules 19(4): 1091-1099.
- Salvatori, D.C.F.; Dorssers, L.C.J.; Gillis, A.J.M.; Perretta, G.; Agthoven, T. van; Fernandes, M.G.; Stoop, H.; Prins, J.B.; Oosterhuis, J.W.; Mummery, C. & Looijenga, L.H.J. (2018), The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays, Stem Cell Reports 11(6): 1493-1505.
- van Helden R. W. J., Bellin M., Orlova V. & Mummery C. L. (2018), Metabolic characterization of hiPSC-derived cardiomyocytes from patients suffering from infantile cardiomyopathy, Human Gene Therapy 29(12): A132-A132.
- Allison, T.F.; Andrews, P.W.; Avior, Y.; Barbaric, I.; Benvenisty, N.; Bock, C.; Brehm, J.; Brustle, O.; Damjanov, I.; Elefanty, A.; Felkner, D.; Gokhale, P.J.; Halbritter, F.; Healy, L.E.; Hu, T.X.; Knowles, B.B.; Loring, J.F.; Ludwig, T.E.; Mayberry, R.; Micallef, S.; Mohamed, J.S.; Muller, F.J.; Mummery, C.L.; Nakatsuji, N.; Ng, E.S.; Oh, S.K.W.; O'Shea, O.; Pera, M.F.; Reubinoff, B.; Robson, P.; Rossant, J.; Schuldt, B.M.; Solter, D.; Sourris, K.; Stacey, G.; Stanley, E.G.; Suemori, H.; Takahashi, K.; Yamanaka, S. & Int Stem Cell Initiative (2018), Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells, Nature Communications 9.
- Thalgott, J.H.; Dos-Santos-Luis, D.; Hosman, A.E.; Martin, S.; Lamande, N.; Bracquart, D.; Srun, S.; Galaris, G.; Boer, H.C. de; Tual-Chalot, S.; Kroon, S.; Arthur, H.M.; Cao, Y.H.; Snijder, R.J.; Disch, F.; Mager, J.J.; Rabelink, T.J.; Mummery, C.L.; Raymond, K. & Lebrin, F. (2018), Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2, Circulation 138(23): 2698-2712.
- Halaidych, O.V.; Freund, C.; Hil, F. van den; Salvatori, D.C.F.; Riminucci, M.; Mummery, C.L. & Orlova, V.V. (2018), Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells, Stem Cell Reports 10(5): 1642-1656.
- Tertoolen, L.G.J.; Braam, S.R.; Meer, B.J. van; Passier, R. & Mummery, C.L. (2018), Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes, Biochemical and Biophysical Research Communications 497(4): 1135-1141.
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- Cai, J.; Orlova, V.V.; Cai, X.J.; Eekhoff, E.M.W.; Zhang, K.Q.; Pei, D.Q.; Pan, G.J.; Mummery, C.L. & Dijke, P. ten (2015), Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva, Stem Cell Reports 5(6): 963-970.
- Roost, M.S.; Iperen, L. van; Ariyurek, Y.; Buermans, H.P.; Arindrarto, W.; Devalla, H.D.; Passier, R.; Mummery, C.L.; Carlotti, F.; Koning, E.J.P. de; Zwet, E.W. van; Goeman, J.J. & Lopes, S.M.C.D. (2015), KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas, Stem Cell Reports 4(6): 1112-1124.
- Orlova, V.; Freund, C.; Hil, L. van den; Reurer, S.P.; Hawinkels, L.; Duffhues, G.S.; Disch, F.; Hans, J.M.; Snijder, R.; Westermann, K.; Dijke, P. ten & Mummery, C. (2015), Modeling hereditary haemorrhagic telangiectasia (HHT) with patient specific induced pluripotent stem cells (IPSCS), Angiogenesis 18(4): 532-532.
- Eschenhagen, T.; Mummery, C. & Knollmann, B.C. (2015), Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes, Cardiovascular Research 105(4): 424-438.
- Birket, M.J. & Mummery, C.L. (2015), Pluripotent stem cell derived cardiovascular progenitors - A developmental perspective, Developmental Biology 400(2): 169-179.
- Andrews, P.W.; Baker, D.; Benvinisty, N.; Miranda, B.; Bruce, K.; Brustle, O.; Choi, M.; Choi, Y.M.; Crook, J.M.; Sousa, P.A. de; Dvorak, P.; Freund, C.; Firpo, M.; Furue, M.K.; Gokhale, P.; Ha, H.Y.; Han, E.; Haupt, S.; Healy, L.; Hei, D.J.; Hovatta, O.; Hunt, C.; Hwang, S.M.; Inamdar, M.S.; Isasi, R.M.; Jaconi, M.; Jekerle, V.; Kamthorn, P.; Kibbey, M.C.; Knezevic, I.; Knowles, B.B.; Koo, S.K.; Laabi, Y.; Leopoldo, L.; Liu, P.; Lomax, G.P.; Loring, J.F.; Ludwig, T.E.; Montgomery, K.; Mummery, C.; Nagy, A.; Nakamura, Y.; Nakatsuji, N.; Oh, S.; Oh, S.K.; Otonkoski, T.; Pera, M.; Peschanski, M.; Pranke, P.; Rajala, K.M.; Rao, M.; Ruttachuk, R.; Reubinoff, B.; Ricco, L.; Rooke, H.; Sipp, D.; Stacey, G.N.; Suemori, H.; Takahashi, T.A.; Takada, K.; Talib, S.; Tannenbaum, S.; Yuan, B.Z.; Zeng, F. & Zhou, Q. (2015), Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI), Regenerative Medicine 10(2): 1-44.
- Greber, B.; Verkerk, A.O.; Seebohm, G.; Mummery, C.L. & Bellin, M. (2015), Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations, Proceedings of the National Academy of Sciences 112(16): E1969-E1969.
- Berg, C.W. van den; Okawa, S.; Lopes, S.M.C.D.; Iperen, L. van; Passier, R.; Braam, S.R.; Tertoolen, L.G.; Sol, A. del; Davis, R.P. & Mummery, C.L. (2015), Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells, Development 142(18): 3231-U263.
- Orlova, V.V. & Mummery, C.L. (2015), What Endothelial Cells from Patient iPSCs Can Tell Us about Aortic Valve Disease, Cell Stem Cell 16(5): 455-457.
- Pera, M.F.; Wert, G. de; Dondorp, W.; Lovell-Badge, R.; Mummery, C.L.; Munsie, M. & Tam, P.P. (2015), What if stem cells turn into embryos in a dish?, Nature Methods 12(10): 917-919.
- Bernardo, A.D.; Thorsteinsdottir, S. & Mummery, C.L. (2015), Advantages of the avian model for human ovarian cancer, Molecular and Clinical Oncology.
- Devalla, H.D.; Schwach, V.; Ford, J.W.; Milnes, J.T.; El-Haou, S.; Jackson, C.; Gkatzis, K.; Elliott, D.A.; Lopes, S.M.C.D.; Mummery, C.L.; Verkerk, A.O. & Passier, R. (2015), Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology, EMBO Molecular Medicine 7(4): 394-410.
- Dambrot, C.; Buermans, H.P.J.; Varga, E.; Kosmidis, G.; Langenberg, K.; Casini, S.; Elliott, D.A.; Dinnyes, A.; Atsma, D.E.; Mummery, C.L.; Braam, S.R. & Davis, R.P. (2014), Strategies for rapidly mapping proviral integration sites and assessing cardiogenic potential of nascent human induced pluripotent stem cell clones, Experimental Cell Research 327(2): 297-306.
- Skelton, R.J.P.; Costa, M.; Anderson, D.J.; Bruveris, F.; Finnin, B.W.; Koutsis, K.; Arasaratnam, D.; White, A.J.; Rafii, A.; Ng, E.S.; Elefanty, A.G.; Stanley, E.G.; Pouton, C.W.; Haynes, J.M.; Ardehali, R.; Davis, R.P.; Mummery, C.L. & Elliott, D.A. (2014), SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development, Stem Cell Research 13(1): 172-179.
- Dambrot, C.; Braam, S.R.; Tertoolen, L.G.J.; Birket, M.; Atsma, D.E. & Mummery, C.L. (2014), Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes.
- Mummery, C.L. (2014), Cardiomyocytes from human pluripotent stem cells: the new patient in safety pharmacology, drug discovery and disease, European Journal of Clinical Investigation 44: 5-5.
- Liu, Z.; Lebrin, F.; Maring, J.A.; Driesche, S. van den; Brink, S. van der; Dinther, M. van; Thorikay, M.; Martin, S.; Kobayashi, K.; Hawinkels, L.J.A.C.; Meeteren, L.A. van; Pardali, E.; Korving, J.; Letarte, M.; Arthur, H.M.; Theuer, C.; Goumans, M.J.; Mummery, C. & Dijke, P. ten (2014), ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis, PLoS ONE 9(1).
- Mummery, C.L. (2014), Putting stem cell to work in understanding gender differences, European Journal of Clinical Investigation 44: 4-4.
- Novakovic, G.V.; Eschenhagen, T. & Mummery, C. (2014), Myocardial Tissue Engineering: In Vitro Models, Cold Spring Harbor perspectives in medicine 4(3).
- Casini, S.; Bellin, M.; Davis, R.P.; Aniello, C. d'; Haas, J.; Ward-van Oostwaard, D.; Tertoolen, L.G.J.; Laugwitz, K.L.; Moretti, A. & Mummery, C.L. (2014), Isogenic Sets of Human Pluripotent Stem Cells as Model of LQT2 Syndrome, Biophysical Journal 106(2): 552A-553A.
- Soares, F.A.C.; Sheldon, M.; Rao, M.; Mummery, C. & Vallier, L. (2014), International Coordination of Large-Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper, Stem Cell Reports 3(6): 931-939.
- Orlova, V.V.; Hil, F.E. van den; Petrus-Reurer, S.; Drabsch, Y.; Dijke, P. ten & Mummery, C.L. (2014), Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells, Nature Protocols 9(6): 1514-1531.
- Orlova, V.V.; Drabsch, Y.; Freund, C.; Petrus-Reurer, S.; Hil, F.E. van den; Muenthaisong, S.; Dijke, P. ten & Mummery, C.L. (2014), Functionality of Endothelial Cells and Pericytes From Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts, Arteriosclerosis, Thrombosis, and Vascular Biology 34(1): 177-+.
- Orlova, V.V.; Freund, C.; Petrus-Reurer, S.; Hil, F.E. van den; Drabsch, Y.; Dijke, P. ten & Mummery, C.L. (2014), Differentiation and functionality of endothelial cells and pericytes from human induced pluripotent stem cells, Angiogenesis 17(3): 760-760.
- Mummery, C. (2014), Derivatives of Human Pluripotent Stem Cells: the new patient?, Human Gene Therapy 25(11): A16-A16.
- Mikkers, H.M.; Feund, C.; Mummery, C.L. & Hoeben, R.C. (2014), Cell Replacement Therapies: Is It Time to Reprogram?, Human Gene Therapy 25(10): 866-874.
- Richter, A.; Valdimarsdottir, L.; Hrafnkelsdottir, H.E.; Runarsson, J.F.; Omarsdottir, A.R.; Ward-van Oostwaard, D.; Mummery, C. & Valdimarsdottir, G. (2014), BMP4 Promotes EMT and Mesodermal Commitment in Human Embryonic Stem Cells via SLUG and MSX2, STEM CELLS 32(3): 636-648.
- Forrest, A.R.R.; Kawaji, H.; Rehli, M.; Baillie, J.K.; Hoon, M.J.L. de; Haberle, V.; Lassmann, T.; Kulakovskiy, I.V.; Lizio, M.; Itoh, M.; Andersson, R.; Mungall, C.J.; Meehan, T.F.; Schmeier, S.; Bertin, N.; Jorgensen, M.; Dimont, E.; Arner, E.; Schmidl, C.; Schaefer, U.; Medvedeva, Y.A.; Plessy, C.; Vitezic, M.; Severin, J.; Semple, C.A.; Ishizu, Y.; Young, R.S.; Francescatto, M.; Alam, I.; Albanese, D.; Altschuler, G.M.; Arakawa, T.; Archer, J.A.C.; Arner, P.; Babina, M.; Rennie, S.; Balwierz, P.J.; Beckhouse, A.G.; Pradhan-Bhatt, S.; Blake, J.A.; Blumenthal, A.; Bodega, B.; Bonetti, A.; Briggs, J.; Brombacher, F.; Burroughs, A.M.; Califano, A.; Cannistraci, C.V.; Carbajo, D.; Chen, Y.; Chierici, M.; Ciani, Y.; Clevers, H.C.; , E. dalla; Davis, C.A.; Detmar, M.; Diehl, A.D.; Dohi, T.; Drablos, F.; Edge, A.S.B.; Edinger, M.; Ekwall, K.; Endoh, M.; Enomoto, H.; Fagiolini, M.; Fairbairn, L.; Fang, H.; Farach-Carson, M.C.; Faulkner, G.J.; Favorov, A.V.; Fisher, M.E.; Frith, M.C.; Fujita, R.; Fukuda, S.; Furlanello, C.; Furuno, M.; Furusawa, J.; Geijtenbeek, T.B.; Gibson, A.P.; Gingeras, T.; Goldowitz, D.; Gough, J.; Guhl, S.; Guler, R.; Gustincich, S.; Ha, T.J.; Hamaguchi, M.; Hara, M.; Harbers, M.; Harshbarger, J.; Hasegawa, A.; Hasegawa, Y.; Hashimoto, T.; Herlyn, M.; Hitchens, K.J.; Sui, S.J.H.; Hofmann, O.M.; Hoof, I.; Hori, F.; Huminiecki, L.; Iida, K.; Ikawa, T.; Jankovic, B.R.; Jia, H.; Joshi, A.; Jurman, G.; Kaczkowski, B.; Kai, C.; Kaida, K.; Kaiho, A.; Kajiyama, K.; Kanamori-Katayama, M.; Kasianov, A.; Kasukawa, T.; Katayama, S.; Kato, S.; Kawaguchi, S.; Kawamoto, H.; Kawamura, Y.I.; Kawashima, T.; Kempfle, J.S.; Kenna, T.J.; Kere, J.; Khachigian, L.M.; Kitamura, T.; Klinken, S.P.; Knox, A.J.; Kojima, M.; Kojima, S.; Kondo, N.; Koseki, H.; Koyasu, S.; Krampitz, S.; Kubosaki, A.; Kwon, A.T.; Laros, J.F.J.; Lee, W.; Lennartsson, A.; Li, K.; Lilje, B.; Lipovich, L.; Mackay-sim, A.; Manabe, R.; Mar, J.C.; Marchand, B.; Mathelier, A.; Mejhert, N.; Meynert, A.; Mizuno, Y.; Morais, D.A.D.; Morikawa, H.; Morimoto, M.; Moro, K.; Motakis, E.; Motohashi, H.; Mummery, C.L.; Murata, M.; Nagao-Sato, S.; Nakachi, Y.; Nakahara, F.; Nakamura, T.; Nakamura, Y.; Nakazato, K.; Nimwegen, E. van; Ninomiya, N.; Nishiyori, H.; Noma, S.; Nozaki, T.; Ogishima, S.; Ohkura, N.; Ohmiya, H.; Ohno, H.; Ohshima, M.; Okada-Hatakeyama, M.; Okazaki, Y.; Orlando, V.; Ovchinnikov, D.A.; Pain, A.; Passier, R.; Patrikakis, M.; Persson, H.; Piazza, S.; Prendergast, J.G.D.; Rackham, O.J.L.; Ramilowski, J.A.; Rashid, M.; Ravasi, T.; Rizzu, P.; Roncador, M.; Roy, S.; Rye, M.B.; Saijyo, E.; Sajantila, A.; Saka, A.; Sakaguchi, S.; Sakai, M.; Sato, H.; Satoh, H.; Savvi, S.; Saxena, A.; Schneider, C.; Schultes, E.A.; Schulze-Tanzil, G.G.; Schwegmann, A.; Sengstag, T.; Sheng, G.J.; Shimoji, H.; Shimoni, Y.; Shin, J.W.; Simon, C.; Sugiyama, D.; Sugiyama, T.; Suzuki, M.; Suzuki, N.; Swoboda, R.K.; Hoen, P.A.C. 't; Tagami, M.; Takahashi, N.; Takai, J.; Tanaka, H.; Tatsukawa, H.; Tatum, Z.; Thompson, M.; Toyoda, H.; Toyoda, T.; Valen, E.; Wetering, M. van de; Berg, L.M. van den; Verardo, R.; Vijayan, D.; Vorontsov, I.E.; Wasserman, W.W.; Watanabe, S.; Wells, C.A.; Winteringham, L.N.; Wolvetang, E.; Wood, E.J.; Yamaguchi, Y.; Yamamoto, M.; Yoneda, M.; Yonekura, Y.; Yoshida, S.; Zabierowski, S.E.; Zhang, P.G.; Zhao, X.B.; Zucchelli, S.; Summers, K.M.; Suzuki, H.; Daub, C.O.; Kawai, J.; Heutink, P.; Hide, W.; Freeman, T.C.; Lenhard, B.; Bajic, V.B.; Taylor, M.S.; Makeev, V.J.; Sandelin, A.; Hume, D.A.; Carninci, P.; Hayashizaki, Y.; FANTOM Consortium & RIKEN PMI CLST DGT (2014), A promoter-level mammalian expression atlas, Nature 507(7493): 462-+.
- Dekkers, O.M.; Mummery, C.L. & Rabelink, T.J. (2014), A Case for Crowd Sourcing in Stem Cell Research, Stem Cells Translational Medicine 3(11): 1259-1261.
- Zhang, M.; D'Aniello, C.; Verkerk, A.O.; Wrobel, E.; Frank, S.; Oostwaard, D.W.; Piccini, I.; Freund, C.; Rao, J.; Seebohm, G.; Atsma, D.E.; Schulze-Bahr, E.; Mummery, C.L.; Greber, B. & Bellin, M. (2014), Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue, Proceedings of the National Academy of Sciences 111(50): E5383-E5392.
- Braam, S.R.; Tertoolen, L.; Casini, S.; Matsa, E.; Lu, H.R.; Teisman, A.; Passier, R.; Denning, C.; Gallacher, D.J.; Towart, R. & Mummery, C.L. (2013), Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes., Stem Cell Research 10(1): 48-56.
- Ribeiro, M.C.; Hoorn, H. van; Monshouwer-Kloots, J.J.; Mummery, C.L.; Schmidt, T. & Passier, R. (2013), Studying Structural And Contractility Defects Of Cardiomyocytes In An In Vitro Model Of Human Hypertrophic Cardiomyopathy, Circulation Research 113(4).
- Birket, M.J.; Casini, S.; Kosmidis, G.; Elliott, D.A.; Gerencser, A.A.; Baartscheer, A.; Schumacher, C.; Mastroberardino, P.G.; Elefanty, A.G.; Stanley, E.G. & Mummery, C.L. (2013), PGC-1 alpha and Reactive Oxygen Species Regulate Human Embryonic Stem Cell-Derived Cardiomyocyte Function, Stem Cell Reports 1(6): 560-574.
- Lensch, M.W. & Mummery, C.L. (2013), From Stealing Fire to Cellular Reprogramming: A Scientific History Leading to the 2012 Nobel Prize, Stem Cell Reports 1(1): 5-17.
- Mummery, C. (2013), Cardiomyocytes from human pluripotent stem cells: the new patient in safety pharmacology, drug discovery and disease, FEBS Journal 280: 441-442.
- Mummery, C. (2013), Cardiomyocytes from human pluripotent stem cells in safety pharmacology, drug discovery and disease, Human Gene Therapy 24(5): A8-A8.
- Braam, S.; Langenberg, K.; Rohrbacher, J.; Grandela, K.C.; Mummery, C.L.; Towart, R.; Cik, M.; Diels, A.; Lu, H.R. & Gallacher, D.J. (2013), Cellular assays for monitoring cardiomyocyte electrophysiology, Journal of Pharmacological and Toxicological Methods 68(1): E9-E9.
- Yi, B.A.; Mummery, C.L. & Chien, K.R. (2013), Direct Cardiomyocyte Reprogramming: A New Direction for Cardiovascular Regenerative Medicine, Cold Spring Harbor perspectives in medicine 3(9).
- Davis, R.P.; Nemes, C.; Varga, E.; Freund, C.; Kosmidis, G.; Gkatzis, K.; Jong, D. de; Szuhai, K.; Dinnyes, A. & Mummery, C.L. (2013), Generation of induced pluripotent stem cells from human foetal fibroblasts using the Sleeping Beauty transposon gene delivery system, Differentiation 86(1-2): 30-37.
- Mummery, C.L. & Lee, R.T. (2013), Is heart regeneration on the right track?, Nature Medicine 19(4): 412-413.
- Bellin, M.; Casini, S.; Davis, R.P.; D'Aniello, C.; Haas, J.; Ward-van Oostwaard, D.; Tertoolen, L.G.J.; Jung, C.B.; Elliott, D.A.; Welling, A.; Laugwitz, K.L.; Moretti, A. & Mummery, C.L. (2013), Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome, EMBO Journal 32(24): 3161-3175.
- Garbern, J.C.; Mummery, C.L. & Lee, R.T. (2013), Model Systems for Cardiovascular Regenerative Biology, Cold Spring Harbor perspectives in medicine 3(4).
- Garbern, J.C.; Mummery, C.L. & Lee, R.T. (2013), Model Systems for Cardiovascular Regenerative Biology, Cold Spring Harbor perspectives in biology 5(4).
- Moretti, A.; Laugwitz, K.L.; Dorn, T.; Sinnecker, D. & Mummery, C. (2013), Pluripotent Stem Cell Models of Human Heart Disease, Cold Spring Harbor perspectives in medicine 3(11).
- Dambrot, C.; Pas, S. van de; Zijl, L. van; Brandl, B.; Wang, J.W.; Schalij, M.J.; Hoeben, R.C.; Atsma, D.E.; Mikkers, H.M.; Mummery, C.L. & Freund, C. (2013), Polycistronic lentivirus induced pluripotent stem cells from skin biopsies after long term storage, blood outgrowth endothelial cells and cells from milk teeth, Differentiation 85(3): 101-109.
- Bianco, P.; Barker, R.; Brustle, O.; Cattaneo, E.; Clevers, H.; Daley, G.Q.; Luca, M. de; Goldstein, L.; Lindvall, O.; Mummery, C.; Robey, P.G.; Brito, C.S.D.E. & Smith, A. (2013), Regulation of stem cell therapies under attack in Europe: for whom the bell tolls, EMBO Journal 32(11): 1489-1495.
- Mummery, C.L. & Roelen, B.A.J. (2013), STEM CELLS Cloning human embryos, Nature 498(7453): 174-175.
- Meer, A.D. van der; Orlova, V.V.; Dijke, P. ten; Berg, A. van den & Mummery, C.L. (2013), Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device, Lab on a Chip 13(18): 3562-3568.
- Spijker, H.S.; Ravelli, R.B.G.; Mommaas-Kienhuis, A.M.; Apeldoorn, A.A. van; Engelse, M.A.; Zaldumbide, A.; Bonner-Weir, S.; Rabelink, T.J.; Hoeben, R.C.; Clevers, H.; Mummery, C.L.; Carlotti, F. & Koning, E.J.P. de (2013), Conversion of Mature Human beta-Cells Into Glucagon-Producing alpha-Cells, Diabetes 62(7): 2471-2480.
- Bellin, M.; Marchetto, M.C.; Gage, F.H. & Mummery, C.L. (2012), Induced pluripotent stem cells: the new patient?, Nature Reviews Molecular Cell Biology 13(11): 713-26.
- Bellin, M.; Marchetto, M.C.; Gage, F.H. & Mummery, C.L. (2012), Induced pluripotent stem cells: the new patient?, Nature Reviews Molecular Cell Biology 13(11): 713-726.
- Rossant, J. & Mummery, C. (2012), PHYSIOLOGY OR MEDICINE Mature cells can be rejuvenated, Nature 492(7427): 56-56.
- Mummery, C. (2012), Pioneer in Cardiovascular Stem Cell Research: Christine Mummery, BSc, PhD, Circulation 126(12): F67-F71.
- Hoof, D. van; Krijgsveld, J. & Mummery, C. (2012), Proteomic Analysis of Stem Cell Differentiation and Early Development, Cold Spring Harbor perspectives in biology 4(3): -.
- Hoof, D. van; Krijgsveld, J. & Mummery, C. (2012), Proteomic analysis of stem cell differentiation and early development., Cold Spring Harbor perspectives in biology 4(3).
- Majesky, M.W. & Mummery, C.L. (2012), Smooth muscle diversity from human pluripotent cells, Nature Biotechnology 30(2): 152-154.
- Moya, I.M.; Umans, L.; Maas, E.; Pereira, P.N.G.; Beets, K.; Francis, A.; Sents, W.; Robertson, E.J.; Mummery, C.L.; Huylebroeck, D. & Zwijsen, A. (2012), Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades, Developmental Cell 22(3): 501-514.
- Freund, C.; Davis, R.P.; Gkatzis, K.; Ward-van Oostwaard, D. & Mummery, C.L. (2012), The first reported generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyocytes in the Netherlands, Netherlands Heart Journal 20: 95-98.
- Chuva de Sousa Lopes, SM and Mummery & CL (2012), Differentiation in early development.
- Sountoulidis, A.; Stavropoulos, A.; Giaglis, S.; Apostolou, E.; Monteiro, R.; Lopes, S.M.C.D.; Chen, H.Y.; Stripp, B.R.; Mummery, C.; Andreakos, E. & Sideras, P. (2012), Activation of the Canonical Bone Morphogenetic Protein (BMP) Pathway during Lung Morphogenesis and Adult Lung Tissue Repair, PLoS ONE 7(8): -.
- Sideras, P.; Stavropoulos, A.; Giaglis, S.; Apostolou, E.; Monteiro, R.; Lopes, S.M.C.D.; Chen, H.Y.; Stripp, B.R.; Mummery, C.; Andreakos, E. & Sountoulidis, A. (2012), ACTIVATION OF THE CANONICAL BONE MORPHOGENETIC PROTEIN (BMP) PATHWAY DURING LUNG MORPHOGENESIS AND ADULT LUNG TISSUE REPAIR.
- Kraushaar, U.; Meyer, T.; Hess, D.; Gepstein, L.; Mummery, C.L.; Braam, S.R. & Guenther, E. (2012), Cardiac safety pharmacology: from human ether-a-gogo related gene channel block towards induced pluripotent stem cell based disease models, Expert Opinion on Drug Safety 11(2): 285-298.
- Chien, K.R.; Yi, B.A.; Xu, H.S. & Mummery, C.L. (2012), Cardiomyocyte reprogramming and the new age of cellular alchemy, Journal of Molecular and Cellular Cardiology 53(3): 311-313.
- Davis, R.P.; Casini, S.; Berg, C.W. van den; Hoekstra, M.; Remme, C.A.; Dambrot, C.; Salvatori, D.; Ward-van Oostwaard, D.; Wilde, A.A.M.; Bezzina, C.R.; Verkerk, A.O.; Freund, C. & Mummery, C.L. (2012), Cardiomyocytes Derived From Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease, Circulation 125(25): 3079-+.
- Davis, R.P.; Casini, S.; Berg, C.W. van den; Hoekstra, M.; Remme, C.A.; Dambrot, C.; Salvatori, D.; Ward-van Oostwaard, D.; Wilde, A.A.M.; Bezzina, C.R.; Verkerk, A.O.; Freund, C. & Mummery, C.L. (2012), Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease., Circulation 125(25): 3079-91.
- Mummery, C.L.; Zhang, J.H.; Ng, E.S.; Elliott, D.A.; Elefanty, A.G. & Kamp, T.J. (2012), Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview., Circulation Research 111(3): 344-58.
- Mummery, C.L.; Zhang, J.H.; Ng, E.S.; Elliott, D.A.; Elefanty, A.G. & Kamp, T.J. (2012), Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes A Methods Overview, Circulation Research 111(3): 344-358.
- Dambrot, A.; Braam, S.R.; Freund, C.M.A.H.; Pas, S. van de; Oostwaard, D.W.V.; Atsma, D.E. & Mummery, C.L. (2012), Human induced pluripotent stem cells as in vitro model for hypertrophic cardiomyopathy, European Heart Journal 33: 22-22.
- Casini, S.; Davis, R.P.; Berg, C.W. van den; Remme, C.A.; Dambrot, C.; Ward-van Oostwaard, D.; Wilde, A.A.M.; Bezzina, C.R.; Verkerk, A.O.; Freund, C. & Mummery, C.L. (2012), Pluripotent Stem Cell Models of a Cardiac Sodium Channelopathy, Biophysical Journal 102(3): 540A-540A.
- Elliott, D.A.; Braam, S.R.; Koutsis, K.; Ng, E.S.; Jenny, R.; Lagerqvist, E.L.; Biben, C.; Hatzistavrou, T.; Hirst, C.E.; Yu, Q.C.; Skelton, R.J.P.; Oostwaard, D.W.V.; Lim, S.M.; Khammy, O.; Li, X.L.; Hawes, S.M.; Davis, R.P.; Goulburn, A.L.; Passier, R.; Prall, O.W.J.; Haynes, J.M.; Pouton, C.W.; Kaye, D.M.; Mummery, C.L.; Elefanty, A.G. & Stanley, E.G. (2011), NKX2-5eGFPw hESCs for isolation of human cardiac progenitors and cardiomyocytes, Nature Methods 8(12): 1037-+.
- Amps, K.; Andrews, P.W.; Anyfantis, G.; Armstrong, L.; Avery, S.; Baharvand, H.; Baker, J.; Baker, D.; Munoz, M.B.; Beil, S.; Benvenisty, N.; Ben-Yosef, D.; Biancotti, J.C.; Bosman, A.; Brena, R.M.; Brison, D.; Caisander, G.; Camarasa, M.V.; Chen, J.M.; Chiao, E.; Choi, Y.M.; Choo, A.B.H.; Collins, D.; Colman, A.; Crook, J.M.; Daley, G.Q.; Dalton, A.; Sousa, P.A. de; Denning, C.; Downie, J.; Dvorak, P.; Montgomery, K.D.; Feki, A.; Ford, A.; Fox, V.; Fraga, A.M.; Frumkin, T.; Ge, L.; Gokhale, P.J.; Golan-Lev, T.; Gourabi, H.; Gropp, M.; Lu, G.X.; Hampl, A.; Harron, K.; Healy, L.; Herath, W.; Holm, F.; Hovatta, O.; Hyllner, J.; Inamdar, M.S.; Irwanto, A.K.; Ishii, T.; Jaconi, M.; Jin, Y.; Kimber, S.; Kiselev, S.; Knowles, B.B.; Kopper, O.; Kukharenko, V.; Kuliev, A.; Lagarkova, M.A.; Laird, P.W.; Lako, M.; Laslett, A.L.; Lavon, N.; Lee, D.R.; Lee, J.E.; Li, C.L.; Lim, L.S.; Ludwig, T.E.; Ma, Y.; Maltby, E.; Mateizel, I.; Mayshar, Y.; Mileikovsky, M.; Minger, S.L.; Miyazaki, T.; Moon, S.Y.; Moore, H.; Mummery, C.; Nagy, A.; Nakatsuji, N.; Narwani, K.; Oh, S.K.W.; Oh, S.K.; Olson, C.; Otonkoski, T.; Pan, F.; Park, I.H.; Pells, S.; Pera, M.F.; Pereira, L.V.; Qi, O.; Raj, G.S.; Reubinoff, B.; Robins, A.; Robson, P.; Rossant, J.; Salekdeh, G.H.; Schulz, T.C.; Sermon, K.; Mohamed, J.S.; Shen, H.; Sherrer, E.; Sidhu, K.; Sivarajah, S.; Skottman, H.; Spits, C.; Stacey, G.N.; Strehl, R.; Strelchenko, N.; Suemori, H.; Sun, B.W.; Suuronen, R.; Takahashi, K.; Tuuri, T.; Venu, P.; Verlinsky, Y.; Ward-van Oostwaard, D.; Weisenberger, D.J.; Wu, Y.; Yamanaka, S.; Young, L.; Zhou, Q. & Int Stem Cell Initiative (2011), Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage, Nature Biotechnology 29(12): 1132-U113.
- Mummery, CL, Wilmut I, van de Stolpe A & Roelen B (2011), Stem Cells: Scientific Facts and Fiction. A popular book on stem cells.
- Mummery, C. (2011), Induced Pluripotent Stem Cells - A Cautionary Note, New England Journal of Medicine 364(22): 2160-2162.
- Morris, E.; Chrobak, I.; Bujor, A.; Hant, F.; Mummery, C.; Dijke, P. ten & Trojanowska, M. (2011), Endoglin Promotes TGF-beta/Smad1 Signaling in Scleroderma Fibroblasts, Journal of Cellular Physiology 226(12): 3340-3348.
- Leeuwis, J.W.; Nguyen, T.Q.; Lopes, S.M.C.D.; Giezen, D.M. van der; Ven, K. van der; Rouw, P.J.H.; Offerhaus, G.J.A.; Mummery, C.L. & Goldschmeding, R. (2011), Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys, Journal of Pathology 224(1): 121-132.
- Denning C, Passier R & Mummery CL (2011), Differentiation of human embryonic stem cells to cardiomyocytes.
- Mummery, C. & Goumans, M.J. (2011), Shedding New Light on the Mechanism Underlying Stem Cell Therapy for the Heart, Molecular Therapy 19(7): 1186-1188.
- Staal, F.J.T.; Baum, C.; Cowan, C.; Dzierzak, E.; Hacein-Bey-Abina, S.; Karlsson, S.; Lapidot, T.; Lemischka, I.; Mendez-Ferrer, S.; Mikkers, H.; Moore, K.; Moreno, E.; Mummery, C.L.; Robin, C.; Suda, T.; Pel, M. van; Brink, G.V.; Zwaginga, J.J. & Fibbe, W.E. (2011), Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications., Leukemia 25(7): 1095-102.
- Mummery, C. (2011), Induced pluripotent stem cells--a cautionary note.
- Fujiwara, M.; Yan, P.S.; Otsuji, T.G.; Narazaki, G.; Uosaki, H.; Fukushima, H.; Kuwahara, K.; Harada, M.; Matsuda, H.; Matsuoka, S.; Okita, K.; Takahashi, K.; Nakagawa, M.; Ikeda, T.; Sakata, R.; Mummery, C.L.; Nakatsuji, N.; Yamanaka, S.; Nakao, K. & Yamashita, J.K. (2011), Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A, PLoS ONE 6(2).
- Mummery, C.L. & Passier, R. (2011), New perspectives on regeneration of the heart., Circulation Research 109(8): 828-9.
- Davis, R.P.; Berg, C.W. van den; Casini, S.; Braam, S.R. & Mummery, C.L. (2011), Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development, Trends in Molecular Medicine 17(9): 475-484.
- Davis, R.P.; Berg, C.W. van den; Casini, S.; Braam, S.R. & Mummery, C.L. (2011), Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development., Trends in Molecular Medicine 17(9): 475-84.
- Mummery, C. & Goumans, M.J. (2011), Shedding new light on the mechanism underlying stem cell therapy for the heart.
- Mummery, C.; Westgren, M. & Sermon, K. (2011), Current controversies in prenatal diagnosis 1: is stem cell therapy ready for human fetuses?, Prenatal Diagnosis.
- Mummery, C.; Westgren, M. & Sermon, K. (2011), Current controversies in prenatal diagnosis 1: is stem cell therapy ready for human fetuses?, Prenatal Diagnosis 31(3): 228-30.
- Ramkisoensing, A.A.; Pijnappels, D.A.; Askar, S.F.A.; Passier, R.; Swildens, J.; Goumans, M.J.; Schutte, C.I.; Vries, A.A.F. de; Scherjon, S.; Mummery, C.L.; Schalij, M.J. & Atsma, D.E. (2011), Human Embryonic and Fetal Mesenchymal Stem Cells Differentiate toward Three Different Cardiac Lineages in Contrast to Their Adult Counterparts, PLoS ONE 6(9).
- Dambrot, C.; Passier, R.; Atsma, D. & Mummery, C.L. (2011), Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models., Biochemical Journal 434(1): 25-35.
- Dambrot, C.; Passier, R.; Atsma, D. & Mummery, C.L. (2011), Cardiomyocyte differentiation of pluripotent stem cells and their use as cardiac disease models, Biochemical Journal 434: 25-35.
- Staal, F.J.T.; Baum, C.; Cowan, C.; Dzierzak, E.; Hacein-Bey-Abina, S.; Karlsson, S.; Lapidot, T.; Lemischka, I.; Mendez-Ferrer, S.; Mikkers, H.; Moore, K.; Moreno, E.; Mummery, C.L.; Robin, C.; Suda, T.; Pel, M. van; Brink, G.V.; Zwaginga, J.J. & Fibbe, W.E. (2011), Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications, Leukemia 25(7): 1095-1102.
- Eldik, W. van; Beqqali, A.; Monshouwer-Kloots, J.; Mummery, C. & Passier, R. (2011), Cytoskeletal heart-enriched actin-associated protein (CHAP) is expressed in striated and smooth muscle cells in chick and mouse during embryonic and adult stages., International Journal of Developmental Biology 55(6): 649-55.
- Laake, L.W. van; Donselaar, E.G. van; Monshouwer-Kloots, J.; Schreurs, C.; Passier, R.; Humbel, B.M.; Doevendans, P.A.; Sonnenberg, A.; Verkleij, A.J. & Mummery, C.L. (2010), Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes, Cellular and Molecular Life Sciences 67(2): 277-290.
- Braam, S.R.; Nauw, R.; Ward-van Oostwaard, D.; Mummery, C.; Passier, R.; Beyar, R. & Landesberg, A. (2010), Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation., Annals of the New York Academy of Sciences 1188: 52-7.
- Denning, C, Passier R & Mummery C (2010), Chapter 15: Differentiation of human embryonic stem cells to cardiomyocytes.
- Freund, C.; Davis, R.P.; Gkatzis, K.; Ward-van Oostwaard, D. & Mummery, C.L. (2010), The first reported generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyocytes in the Netherlands, Netherlands Heart Journal 18(1): 51-54.
- Mummery, C. (2010), Sorting cardiomyocytes: a simple solution after all?, Nature Methods 7(1): 40-42.
- C. Mummery (2010), Treating cardiac disorders with stem cells.
- Laake, L.W. van; Passier, R.; Ouden, K. den; Schreurs, C.; Monshouwer-Kloots, J.; Ward-Van Oostwaard, D.; Echteld, C. van; Doevendans, P.A. & Mummery, C.L. (2010), Human embryonic stem cell-derived cardiomyocytes improve cardiac function after myocardial infarction: paracrine effects outweigh the contribution of active contractile force, European Heart Journal 31: 79-79.
- Hoof, D. van; Dormeyer, W.; Braam, S.R.; Passier, R.; Monshouwer-Kloots, J.; Ward-van Oostwaard, D.; Heck, A.J.R.; Krijgsveld, J. & Mummery, C.L. (2010), Identification of Cell Surface Proteins for Antibody-Based Selection of Human Embryonic Stem Cell-Derived Cardiomyocytes, Journal of Proteome Research 9(3): 1610-1618.
- Kobayakawa, S.; Lie-Venema, H.; Mummery, C.L. & Lopes, S.M.C.D. (2010), Human germ cells development during the first trimester-X chromosome activity in human germ cells, Differentiation 80: S48S48.
- Passier, R. & Mummery, C. (2010), Getting to the Heart of the Matter: Direct Reprogramming to Cardiomyocytes, Cell Stem Cell 7(2): 139-141.
- Lebrin, F.; Srun, S.; Raymond, K.; Martin, S.; Brink, S. van den; Freitas, C.; Breant, C.; Mathivet, T.; Larrivee, B.; Thomas, J.L.; Arthur, H.M.; Westermann, C.J.J.; Disch, F.; Mager, J.J.; Snijder, R.J.; Eichmann, A. & Mummery, C.L. (2010), Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia, Nature Medicine 16(4): 420U101.
- Lebrin, F.; Freund, C.; Braam, S.; Passier, R.; Laake, L. van; Ward, D.; Tertoolen, L.; Davis, R. & Mummery, C. (2010), Cardiovascular derivatives of embryonic stem cells in cardiac repair and drug discovery, Differentiation 80: S12-S12.
- Braam, S.R.; Tertoolen, L.; Stolpe, A. van de; Meyer, T.; Passier, R. & Mummery, C.L. (2010), Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes., Stem Cell Research 4(2): 107-16.
- Koyanagi, M.; Iwasaki, M.; Rupp, S.; Tedesco, F.S.; Yoon, C.H.; Boeckel, J.N.; Trauth, J.; Schutz, C.; Ohtani, K.; Goetz, R.; Iekushi, K.; Bushoven, P.; Momma, S.; Mummery, C.; Passier, R.; Henschler, R.; Akintuerk, H.; Schranz, D.; Urbich, C.; Galvez, B.G.; Cossu, G.; Zeiher, A.M. & Dimmeler, S. (2010), Sox2 Transduction Enhances Cardiovascular Repair Capacity of Blood-Derived Mesoangioblasts, Circulation Research 106(7): 1290U281.
- Passier, R. & Mummery, C. (2010), Getting to the heart of the matter: direct reprogramming to cardiomyocytes., Cell Stem Cell 7(2): 139-41.
- Braam SR, Denning C & Mummery CL (2010), Genetic manipulation of human embryonic stem cells in serum and feeder-free media., Methods in Molecular Biology 584: 413-23.
- Beqqali, A.; Monshouwer-Kloots, J.; Monteiro, R.; Welling, M.; Bakkers, J.; Ehler, E.; Verkleij, A.; Mummery, C. & Passier, R. (2010), CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function, Journal of Cell Science 123(7): 1141-1150.
- Mummery, C.L.; Davis, R.P. & Krieger, J.E. (2010), Challenges in Using Stem Cells for Cardiac Repair, Science Translational Medicine 2(27).
- Kearns-Jonker, M.; Dai, W.D.; Gunthart, M.; Girish, N.; Pera, M.; Mummery, C. & Kloner, R.A. (2010), Genetically Engineered Mesenchymal Stem Cells Confer Beneficial Effects on Both Co-transplanted Human Embryonic Stem Cell Derived Cardiomyocytes as well as the Recipient Heart, Circulation 122(21).
- Post, S.; Smits, A.M.; Broek, A.J. van den; Sluijter, J.P.G.; Hoefer, I.E.; Janssen, B.J.; Snijder, R.J.; Mager, J.J.; Pasterkamp, G.; Mummery, C.L.; Doevendans, P.A. & Goumans, M.J. (2010), Impaired recruitment of HHT-1 mononuclear cells to the ischaemic heart is due to an altered CXCR4/CD26 balance, Cardiovascular Research 85(3): 494-502.
- van Laake LW, Passier R, den Ouden K, Schreurs C, Monshouwer-Kloots J, Ward-van Oostwaard D, van Echteld CJ, Doevendans PA & Mummery CL (2009), Improvement of mouse cardiac function by hESC-derived cardiomyocytes correlates with vascularity but not graft size, Stem Cell Research 3(2-3): 106-112.
- Beqqali A, van Eldik W, Mummery C & Passier R (2009), Human stem cells as a model for cardiac differentiation and disease, Cellular and Molecular Life Sciences 66(5): 800-813.
- Beqqali A, van Eldik W, Mummery C & Passier R (2009), Human stem cells as a model for cardiac differentiation and disease., Cellular and Molecular Life Sciences 66(5): 800-13.
- Braam SR, Passier R & Mummery CL (2009), Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery, Trends in Pharmacological Sciences 30(10): 536-545.
- Itoh F, Itoh S, Carvalho RLC, Adachi T, Ema M, Goumans MJ, Larsson J, Karlsson S, Takahashi S & Mummery CL (2009), Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation, Laboratory Investigation 89(7): 800-810.
- Boeckel JN, Koyanagi M, Ohtani K, Mummery C, Momma S, Zeiher AM & Dimmeler S (2009), Comparing Epigenetic Modifications of Adult Progenitor Cells, Circulation 120(18): S1079S1079.
- Mummery C (2009), Cardiovascular derivatives of embryonic stem cells in cardiac repair and drug discovery, Human Gene Therapy 20(11): 1363-1363.
- Chuva de Sousa Lopes, SM and Mummery & CL. (2009), Differentiation in early development.
- Mummery C (2009), Cardiomyocytes from Human Embryonic Stem Cells, Journal of General Physiology 134(1): 14A14A.
- Freund C & Mummery CL (2009), Prospects for Pluripotent Stem Cell-Derived Cardiomyocytes in Cardiac Cell Therapy and as Disease Models, Journal of Cellular Biochemistry 107(4): 592-599.
- Van Hoof D, Munoz J, Braam SR, Pinkse MWH, Linding R, Heck AJR, Mummery CL & Krijgsveld J (2009), Phosphorylation Dynamics during Early Differentiation of Human Embryonic Stem Cells, Cell Stem Cell 5(2): 214-226.
- Davis R, Freund C, Tertoolen L, Remme CA, Bezzina C & Mummery C (2009), Mouse pluripotent stem cell models of a human cardiac sodium channelopathy, Mechanisms of Development 126: S246S246.
- Andrews PW, Arias-Diaz J, Auerbach J, Alvarez M, Ahrlund-Richter L, Baker D, Benvenisty N, Ben-Josef D, Blin G, Borghese L, Borstlap J, Bruce K, Brustle O, Buckle R, Camby C, Choo A, Chen W, Collins D, Colman A & Crombie C (2009), Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes, Stem Cell Reviews and Reports 5(4): 301-314.
- Smits AM, van Laake LW, den Ouden K, Schreurs C, Szuhai K, van Echteld CJ, Mummery CL, Doevendans PA & Goumans MJ (2009), Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium, Cardiovascular Research 83(3): 527-535.
- Nijmeijer RM, Leeuwis JW, DeLisio A, Mummery CL & Lopes SMCD (2009), Visceral endoderm induces specification of cardiomyocytes in mice, Stem Cell Research 3(2-3): 170-178.
- van Laake LW, Passier R, Doevendans PA & Mummery CL (2008), Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents, Circulation Research 102(9).
- Passier R, van Laake LW & Mummery CL (2008), Stem-cell-based therapy and lessons from the heart, Nature 453(7193).
- Monteiro RM, Lopes SMCD, Bialecka M, de Boer S, Zwijsen A & Mummery CL (2008), Real time monitoring of BMP Smads transcriptional activity during mouse development, genesis 46(7).
- Van Hoof D, Braam SR, Dormeyer W, Oostwaard DWV, Heck AJR, Krijgsveld J & Mummery CL (2008), Feeder-Free Monolayer Cultures of Human Embryonic Stem Cells Express an Epithelial Plasma Membrane Protein Profile, STEM CELLS 26(11).
- Braam SR, Denning C, Matsa E, Young LE, Passier R & Mummery CL (2008), Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification, Nature Protocols 3(9).
- Monteiro R, van Dinther M, Bakkers J, Wilkinson R, Patient R, ten Dijke P & Mummery C (2008), Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish, Developmental Biology 315(1).
- Braam SR, Denning C, van den Brink S, Kats P, Hochstenbach R, Passier R & Mummery CL (2008), Improved genetic manipulation of human embryonic stem cells, Nature Methods 5(5).
- Smits Anke M., van Laake Linda W., den Ouden Krista, Schreurs Chantal, van Echteld Coos J., Mummery Christine L., Doevendans Pieter A. & Goumans Marie-Jose (2008), Human Cardiomyocyte Progenitor Cells Regenerate Infarcted Myocardium and Preserve Long-Term Cardiac Function In Mice, Circulation 118(18): S499-S499.
- Van Hoof Dennis, Heck Albert J. R., Krijgsveld Jeroen & Mummery Christine L. (2008), Proteomics and human embryonic stem cells, Stem Cell Research 1(3): 169-182.
- Braam SR, Zeinstra L, Litjens S, Ward-van Oostwaard D, van den Brink S, van Laake L, Lebrin F, Kats P, Hochstenbach R, Passier R, Sonnenberg A & Mummery CL (2008), Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alpha V beta 5 integrin, STEM CELLS 26(9).
- Carvalho RLC, Itoh F, Goumans MJ, Lebrin F, Kato M, Takahashi S, Ema M, Itoh S, van Rooijen M, Bertolino P, ten Dijke P & Mummery CL (2007), Compensatory signalling induced in the yolk sac vasculature by deletion of TGF beta receptors in mice, Journal of Cell Science 120(24).
- Bezooijen, R.L. van; DeRuiter, M.C.; Vilain, N.; Monteiro, R.M.; Visser, A.; Wee-Pals, L. van der; Munsteren, C.J. van; Hogendoorn, P.C.W.; Aguet, M.; Mummery, C.L.; Papapoulos, S.E.; Dijke, P. ten & Lowik, C.W.G.M. (2007), SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development, Developmental Dynamics 236(2).
- de Sousa Lopes SMC, Hassink RJ, Feijen A, van Rooijen MA, Doevendans PA, Tertoolen L, de la Rivere AB & Mummery CL (2006), Patterning the heart, a template for human cardiomyocyte development.
- van Meeteren LA, Ruurs P, Stortelers C, Bouwman P, van Rooijen MA, Pradere JP, Pettit TR, Wakelam MJO, Saulnier-Blache JS, Mummery CL, Moolenaar WH & Jonkers J (2006), Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development, Molecular and Cellular Biology 26(13): 5015-5022.
- van Laake LW, van den Driesche S, Post S, Feijen A, Jansen MA, Driessens MH, Mager JJ, Snijder RJ, Westermann CJJ, Doevendans PA, van Echteld CJA, ten Dijke P, Arthur HM, Goumans MJ, Lebrin F & Mummery CL (2006), Endoglin has a crucial role in blood cell-mediated vascular repair, Circulation 114(21).
- Lopes SMCD, Roelen BAJ, Monteiro RM, Emmens R, Lin HY, Li E, Lawson KA & Mummery CL (2004), BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo, Genes and Development 18(15): 1838-1849.
- Koop EA, Lopes SMCD, Feiken E, Bluyssen HAR, Van Der Valk M, Voest EE, Mummery CL, Moolenaar WH & Gebbink MFBG (2003), Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTP mu gene expression using LacZ knock-in mice, International Journal of Developmental Biology 47(5): 345-354.
- Cachaco AS, Lopes SMCD, Kuikman I, Bajanca F, Abe K, Baudoin C, Sonnenberg A, Mummery CL & Thorsteinsdottir S (2003), Knock-in of integrin beta 1D affects primary but not secondary myogenesis in mice, DEVELOPMENT 130(8): 1659-1671.
- Founding/Associate editor of Stem Cell Reports
- Founding/Associate editor of Stem Cell Reports
- Scientific advisory boards
- Visiting professor