Brandon Bongers
Onderzoeker
- Naam
- Dr. B.J. Bongers
- Telefoon
- 071 5272727
- b.j.bongers@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0003-1322-2369
Meer informatie is beschikbaar op de Engelstalige profielpagina.
Meer informatie over Brandon Bongers
Onderzoeker
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
Gast Wetenschapper
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Bongers B.J. (8 mei 2024), The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment (Dissertatie. Leiden Academic Centre for Drug Research (LADCR), Faculty of Science, Leiden University). Promotor(en): Westen G.J.P. van & IJzerman A.P.
- Béquignon O.J.M., Bongers B.J., Jespers W., IJzerman A.P., Water B. van de & Westen G.J.P. van (2023), Papyrus: a large-scale curated dataset aimed at bioactivity predictions, Journal of Cheminformatics 15(1): 3.
- Bongers B.J., Sijben H.J., Hartog P.B.R., Tarnovskiy A., IJzerman A.P., Heitman L.H. & Westen G.J.P. van (2023), Proteochemometric modeling identifies chemically diverse norepinephrine transporter inhibitors, Journal of Chemical Information and Modeling 63(6): 1745-1755.
- Tuerkova A., Bongers B.J., Norinder U., Ungvári O., Székely V., Tarnovskiy A., Szakács G., Özvegy-Laczka C., Westen G.J.P. van & Zdrazil B. (2022), Identifying novel inhibitors for hepatic organic anion transporting polypeptides by machine learning-based virtual screening, Journal of Chemical Information and Modeling 62(24): 6323-6335.
- Bongers B.J., Gorostiola González M., Wang X., Vlijmen H. van, Jespers W., Gutiérrez-de-Terán H., Ye K., IJzerman A.P., Heitman L.H. & Westen G.J.P. van (2022), Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors, Scientific Reports 12(1): 21534.
- Wang X. Jespers W. Bongers B.J. Habben Jansen M.C.C. Stangenberger C.M. Dilweg M.A. Gutiérrez-de-Terán H. IJzerman A.P. Heitman L.H. Westen G.J.P. van (2020), Characterization of cancer-related somatic mutations in the adenosine A2B receptor, European Journal of Pharmacology 880: 173126.
- Superti-Furga G., Lackner D., Wiedmer T., Ingles-Prieto A., Barbosa B., Girardi E., Goldmann U., Gürtl B., Klavins K., Klimek C., Lindinger S., Liñeiro-Retes E., Müller A.C., Onstein S., Redinger G., Reil D., Sedlyarov V., Wolf G., Crawford M., Everley R., Hepworth D., Liu S., Noell S., Piotrowski M., Stanton R., Zhang H., Corallino S., Faedo A., Insidioso M., Maresca G., Redaelli L., Sassone F., Scarabottolo L., Stucchi M., Tarroni P., Tremolada S., Batoulis H., Becker A., Bender E., Chang Y.N., Ehrmann A., Müller-Fahrnow A., Pütter V., Zindel D., Hamilton B., Lenter M., Santacruz D., Viollet C., Whitehurst C., Johnsson K., Leippe P., Baumgarten B., Chang L., Ibig Y., Pfeifer M., Reinhardt J., Schönbett J., Selzer P., Seuwen K., Bettembourg C., Biton B., Czech J., de Foucauld H., Didier M., Licher T., Mikol V., Pommereau A., Puech F., Yaligara V., Edwards A., Bongers B.J., Heitman L.H., Ijzerman A.P., Sijben H.J., Westen G.J.P. van, Grixti J., Kell D.B., Mughal F., Swainston N., Wright-Muelas M., Bohstedt T., Burgess-Brown N., Carpenter L., Dürr K., Hansen J., Scacioc A., Banci G., Colas C., Digles D., Ecker G., Füzi B., Gamsjäger V., Grandits M., Martini R., Troger F., Altermatt P., Doucerain C., Dürrenberger F., Manolova V., Steck A.L., Sundström H., Wilhelm M. & Steppan C.M. (2020), The RESOLUTE consortium: unlocking SLC transporters for drug discovery, Nature Reviews Drug Discovery 19(7): 429-430.
- Burggraaff L. Lenselink E.B. Jespers W. Engelen J. van Bongers B.J. Gorostiola Gonzalez M. Liu R. Hoos H.H. Vlijmen H. van IJzerman A.P. Westen G.J.P. van (2020), Successive statistical and structure-based modeling to identify chemically novel kinase inhibitors, Journal of Chemical Information and Modeling 60(9): 4283-4295.
- Bongers B.J., IJzerman A.P. & Westen G.J.P. (2019), Proteochemometrics – recent developments in bioactivity and selectivity modeling, Drug Discovery Today: Technologies 32-33: 89-98.
- Lenselink E.B., Dijke N. ten, Bongers B.J., Papadatos G., Vlijmen H. van, Kowalczyk W.J., IJzerman A.P. & Westen G.J.P. van (2017), Beyond the Hype: Deep Neural Networks Outperform Established Methods Using A ChEMBL Bioactivity Benchmark Set, Journal of Cheminformatics 9(1): 45.