Thomas Schmidt
Professor of Structural dynamics of biomacromolecules in life processes
- Name
- Prof.dr. T. Schmidt
- Telephone
- +31 71 527 5982
- schmidt@physics.leidenuniv.nl
- ORCID iD
- 0000-0002-0045-1851
More information about Thomas Schmidt
News
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From forming embryo to cancer metastasis: the significance of collective cell movement -
Probing the secret forces of pericytes -
Making cells ultra-heavy -
Understanding metastasis: Science Groot grant for Erik Danen -
Science Groot funding for Leiden scientists -
What is the shape of cells? -
Essential protein for metastasis identified -
Stefano Coppola Receives AXA RF Fellowship to Study Pancreatic Cancer -
Cancer cell mechanism found to be used against itself -
Counting Molecules in Living cells -
Movements of steroid receptors inside the cell nucleus unraveled
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Folded DNA unravelled
In the media
Former Phd candidates
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Julia Eckert -
Olga Iendaltseva
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Patrick van den Berg
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Thomas Brouwer
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Wim Pomp
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Sara Carozza
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Casper van der Wel
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Hayri Balcıoğlu
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Rolf Harkes
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Ruth Buning
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Elena Beletkaia
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Hedde van Hoorn
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He Meng
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Anna Pezzarossa
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Fan-Tso Chien
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Wiepke Jelle Anthonie Koopmans
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Stefan Semrau
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Paige Marie Shaklee
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Maarten Christiaan Kruithof
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Laurentius Holtzer
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Freek van Hemert
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Sandra de Keizer
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Ralf Schmauder
Professor of Structural dynamics of biomacromolecules in life processes
- Science
- Leiden Instituut Onderzoek Natuurkunde
- LION - Biological & Soft Matter
- Che P.P., Gregori A., Bergonzini C., Ali M., Mantini G., Schmidt. T., Finamore F., Fraga Rodrigues S.M., Frampton A.E., McDonnell L.A., Danen E.H.J., Slotman B.J., Sminia P. & Giovannetti E. (2024), Differential sensitivity to ionizing radiation in gemcitabine- and paclitaxel-resistant pancreatic cancer cells, International Journal of Radiation Oncology - Biology - Physics 118(5): 1328-1343.
- Liao C., Engelberts P., Ioan-Facsinay A., Klip J.A., Schmidt T., Ruijtenbeek R. & Danen E.H.J. (2024), CD3-engaging bispecific antibodies trigger a paracrine regulated wave of T-cell recruitment for effective tumor killing, Communications Biology 7(1): 983.
- Bergonzini C., Gregori A., Hagen T.M.S., Noord V.E. van der, Water B. van der, Zweemer A.J.M., Capula M., Mantini G., Botta A., Finamore F., Garajova I., McDonnell L.A., Schmidt T, Giovannetti E. & Danen E.H.J. (2023), ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells. Journal of Experimental & Clinical Cancer Research. [working paper].
- Duranti C., Iorio J., Bagni G., Altadonna G.C., Fillion T., Lulli M., D'Alessandro F.N., Montalbano A., Lastraioli E., Fanelli D., Coppola S., Schmidt T., Piazza F., Becchetti A. & Arcangeli A. (2023), Integrins regulate hERG1 dynamics by girdin-dependent Gαi3: signaling and modeling in cancer cells, Life science alliance 7(1): e202302135.
- Ecker J., Ladoux B., Giomi L. & Schmidt T. (2023), Hexanematic crossover in epithelial monolayers depends on cell adhesion and cell density, Nature Communications 14: 5762.
- Gregori A., Bergonzini C., Capula M., Mantini G., Khojasteh-Leylakoohi F., Comandatore A., Khalili-Tanha G., Khooei A., Morelli L., Avan A., Danen E.H., Schmidt T. & Giovannetti E. (2023), Prognostic significance of integrin subunit alpha 2 (ITGA2) and role of mechanical cues in resistance to gemcitabine in pancreatic ductal adenocarcinoma (PDAC), Cancers 15(3): 628.
- Rodrigues de Mercado R.R., Hoorn H. van, Valois M. de, Backendorf C., Eckert J. & Schmidt T. (2022), Characterization of cell-induced astigmatism in high-resolution imaging, Biomedical Optics Express 13(1): 464-473.
- Radoslaw J., Jong B. de, Hage P. van, Rhiemus M., Steenis F. van, Noort S.J.T. van, Schmidt T. & Schaaf M.J.M (2022), Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue, Disease Models & Mechanisms 15(2): dmm049099.
- Balcioglu H.E., Harkes R., Danen E.H.J. & Schmidt T. (2022), Substrate rigidity modulates traction forces and stoichiometry of cell–matrix adhesions, The Journal of Chemical Physics 156(8): 1-13 (085101).
- Mytiliniou M., Wondergem A.J., Schmidt T. & Heinrich D.M. (2022), Impact of neurite alignment on organelle motion, Journal of The Royal Society Interface 19(187): 20210617.
- Eckert J., Abouleila Y.A.M.I. & Schmidt T. (2021), Single cell micro-pillar-based characterization of endothelial and fibroblast cell mechanics, Micro 1(2): 242-249.
- Arslan F.N., Eckert J., Schmidt T. & Heisenberg C.P. (2021), Holding it together: when cadherin meets cadherin, Biophysical Journal 120(19): 7182-4192.
- Eckert J., Loon L. van, Eng L.M. & Schmidt T. (2021), Hypergravity affects cell traction forces of fibroblasts, Biophysical Journal 120(5): 773-780.
- Iendaltseva O. Orlova V.V. Mummery C.L. Danen E.H.J. Schmidt T. (2020), Fibronectin Patches as Anchoring Points for Force Sensing and Transmission in Human Induced Pluripotent Stem Cell-Derived Pericytes, Stem Cell Reports 14(6): 1107-1122.
- Schakenraad K. Ernst J. Pomp W. Danen E.H.J. Merks R.M.H. Schmidt T. Giomi L. (2020), Mechanical interplay between cell shape and actin cytoskeleton organization, Soft Matter 16(27): 6328-6343.
- Wang W., Zuidema A., Molder L. te, Nahidiazar L., Hoekman L., Schmidt T., Coppola S. & Sonnenberg A. (2020), Hemidesmosomes modulate force generation via focal adhesions, Journal of Cell Biology 219(2): e201904137.
- Coppola S., Schmidt T., Ruocco G. & Antonacci G. (2019), Quantifying cellular forces and biomechanical properties by correlative micropillar traction force and Brillouin microscopy, Biomedical Optics Express 10(5): 2202-2212.
- Firuzi O., Che P.P., El Hassouni B., Buijs M., Coppola S., Lohr M., Funel N., Heuchel R., Carnevale I., Schmidt T., Mantini G., Avan A., Saso L., Peters G.J. & Giovannetti E. (2019), Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells, Cancers 11(5): 638.
- Keizer V.I.P., Coppola S., Houtsmuller A.B., Geverts B., Royen M.E. van, Schmidt T. & Schaaf M.J.M. (2019), Repetitive switching between DNA-binding modes enables target finding by the glucocorticoid receptor, Journal of Cell Science 132(5): jcs217445.
- Manoli S., Coppola S., Duranti C., Lulli M., Magni L., Kuppalu N., Nielsen N., Schmidt T., Schwab A., Becchetti A. & Arcangeli A. (2019), The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells, Cancers 11(2): 135.
- Schmidt T., Balcioglu H.E., Harkes R. & Danen E.H.J. (2018), Substrate Rigidity Modulates the Composition in Cell-Matrix Adhesions, Biophysical Journal 114(3): 19A-19A.
- Pomp W., Schakenraad K.K., Balcioglu H.E., Hoorn H. van der, Danen E.H.J, Merks R.M.H, Schmidt T. & Giomi L. (2018), Cytoskeletal anisotropy controls geometry and forces of adherent cells, Physical Review Letters 121(17): 178101.
- Coppola S., Carnevale I., Danen E.H.J., Peters G.J., Schmidt T., Assaraf Y.G. & Giovannetti E. (2017), A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemoth 31: 43-51.
- Becchetti A., Crescioli S., Zanieri F., Petroni G., Mercatelli R., Coppola S., Gasparoli L., D’Amico M., Pillozzi S., Crociani O., Stefanini M., Fiore A., Carraresi L., Morello V., Manoli S., Brizzi M.F., Ricci D., Rinaldi M., Masi A., Schmidt T., Quercioli F., Defilippi P. & Arcangeli A. (2017), The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression, Science Signaling 10(473): eaaf3236.
- Richter D., Moraga I., Winkelmann H., Birkholz O., Wilmes S., Schulte M., Kraich M., Kenneweg H., Beutel O., Selenschik P., Paterok D., Gavutis M., Schmidt T., Garcia K.C., Müller T.D. & Piehler J. (2017), Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments, Nature Communications 8: 15976.
- Askes S.H.C., Leeuwenburgh V.C., Pomp W., Arjmandi-Tash H., Tanase S., Schmidt T. & Bonnet S.A. (2017), Water-Dispersible Silica-Coated Upconverting Liposomes: Can a Thin Silica Layer Protect TTA-UC against Oxygen Quenching?, ACS Biomaterials Science and Engineering 3(3): 322-334.
- Harkes R., Balcioglu H.E., Danen E.H.J. & Schmidt T. (2016), Molecular Counting in Traction Force Microscopy. . Baltimore, USA.
- Apetri M.M., Harkes R., Subramanian V., Canters G.W., Schmidt T. & Aartsma T.J. (2016), Direct observation of α-synuclein amyloid aggregates in endocytic vesicles of neuroblastoma cells, 11(4): e0153020.
- Moeton M., Stassen O.M.J.A., Sluijs J.A., Meer V.W.N. van der, Kluivers L.J., Hoorn H. van, Schmidt T., Reits E.A.J., Strien M.E. van & Hol E.M. (2016), GFAP isoforms control intermediate filament network dynamics, cell morphology, and focal adhesions, Cellular and Molecular Life Sciences 73(21): 4101-4120.
- Beletkaia E., Fenz S.A., Pomp W., Snaar-Jagalska B.E., Hogendoorn P.W.C. & Schmidt T. (2016), CXCR4 signaling is controlled by immobilization at the plasma membrane, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863(4): 607–616.
- Askes S.H.C., Pomp W., Hopkins S.L., Kros A., Wu S., Schmidt T. & Bonnet S.A. (2016), Imaging upconverting polymersomes in cancer cells: biocompatible anti-oxidants brighten triplet-triplet annihilation upconversion, Small 12(40): 5579-5590.
- Tulotta C., Stefanescu C., Beletkaia E., Bussmann J., Tarbashevich K., Schmidt T. & Snaar-Jagalska B.E. (2016), Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model, Disease Models & Mechanisms 9(2): 141-153.
- Pomp W., Schakenraad K.K., Hoorn H. van, Balciglu H.E., Danen E.H.J., Giomi L. & Schmidt T. (2016), Balance of Isotropic and Directed Forces Determines Cell Shape, Biophysical Journal 110(3): 305A-305A.
- Harkes R., Keizer V.I.P., Schaaf M.J.M. & Schmidt T. (2015), Depth-of-Focus Correction in Single-Molecule Data Allows Analysis of 3D Diffusion of the Glucocorticoid Receptor in the Nucleus, PLoS ONE 10(11): e0141080.
- Balcioglu H.E., Hoorn H. van, Donato D.M., Schmidt T. & Danen E.H.J. (2015), The integrin expression profile modulates orientation and dynamics of force transmission at cell–matrix adhesions, Journal of Cell Science 128(7): 1316-1326.
- Askes S.H.C., López Mora N., Harkes R., Koning R.I., Koster B., Schmidt T., Kros A. & Bonnet S.A. (2015), Imaging the lipid bilayer of giant unilamellar vesicles using red-to-blue light upconversion, Chemical Communications 51(44): 9137-9140.
- Balcioglu H.E., Hoorn H. van, Donato D.M., Schmidt T. & Danen E.H.J. (2015), Integrins alpha5beta1 and alphvbeta3 differentially control orientation and dynamics of force transmission at cell matrix adhesions, Journal of Cell Science 128: 1316-1326.
- Jansen K.A., Donato D.M., Balcioglu H.E., Schmidt T., Danen E.H. & Koenderink G.H. (2015), A guide to mechanobiology: Where biology and physics meet, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853(11): 3043-3052.
- Beutel O., Nikolaus J., Birkholz O., You C., Schmidt T., Herrmann A. & Piehler J. (2014), High fidelity Protein Targeting into Membrans Lipid Microdomains in Living Cells, Angewandte Chemie - International Edition in English 53: 1311-1315.
- Sachse R., Dondapati S.K., Fenz S.F., Schmidt T. & Kubick S. (2014), Membrane protein synthesis in cell-free systems: From bio-mimetic systems to bio-membranes, FEBS Letters 588: 2774-2781.
- Fenz S.F., Sachse R., Schmidt T. & Kubrick S. (2014), Cell-free synthesis of membrane proteins: Tailored cell models out of microsomes, Biochimica et Biophysica Acta 1838: 1382-1388.
- Royen M.E. van, Cappellen W.A. van, Geverts B., Schmidt T., Houtsmuller A.B. & Schaaf M.J.M. (2014), Androgen receptor complexes probe DNA for recognition sequences by short random interactions, Journal of Cell Science 127(7): 1406-1416.
- Groeneweg F.L., Royen M.E. van, Fenz F.S., Keizer V.I.P., Geverts B., Prins J., Kloet E.R. de, Houtsmuller A.B., Schmidt T. & Schaaf M.J.M. (2014), Quantitation of Glucocorticoid Receptor DNA-Binding Dynamics by Single-Molecule Microscopy and FRAP, PLoS ONE 9(3): 90532.
- Coppola S., Caracciolo G. & Schmidt T. (2014), Exact occupation probabilities for intermittent transport and application to image correlation spectroscopy, New Journal of Physics 16: 113057.
- Hoorn H. van, Harkes R., Spiesz E.W., Storm C., Noort D. van, Ladoux B. & Schmidt T. (2014), The Nanoscale Architecture of Force-Bearing Focal Adhesions, Nano Letters : .
- Fenz S.F., Sachse R., Schmidt T. & Kubick S. (2013), Cell-free synthesis of membrane proteins: Tailored cell models out of microsomes, Biochimica et Biophysica Acta - Biomembranes : .
- Serge A., Keijzer S. de, Hemert F. van, Hickman M., Hereld D., Spaink H.P., Schmidt T. & Snaar B.E. (2011), Quantification of GPCR internalization by single-molecule microscopy in living cells, Integrative Biology 3(6): 675-683.
- Semrau Stefan, Holtzer Laurent, Gonzalez-Gaitan Marcos & Schmidt Thomas (2011), Quantification of Biological Interactions with Particle Image Cross-Correlation Spectroscopy (PICCS), Biophysical Journal 100(7): 1810-1818.
- Shaklee P.M., Bourel-Bonet L., Dogterom M. & Schmidt T. (2010), Nonprocessive motor dynamics at the microtubule interface, Biophysical Journal 98: 93-100.
- Shaklee P.M., Idema T., Bourel-Bonnet L., Dogterom M. & Schmidt T. (2010), Kinesin recycling in stationary membrane tubes, Biophysical Journal 99: 1835.
- Hemert F. van, Lazova M., Snaar-Jagalska B.E. & Schmidt T. (2010), Mobility of G proteins is heterogeneous and polarized during chemotaxis, Journal of Cell Science 123: 2922-2930.
- Semrau S., Monster M.W.L., Knaap M. van der, Florea B.I., Schmidt T. & Overhand M. (2010), Membrane lysis by gramicidin S visualized in red blood cells and giant vesicles, Biochimica et Biophysica Acta (BBA) - Biomembranes 1798(11): .
- Shaklee P.M., Bourel-Bonnet L., Dogterom M. & Schmidt T. (2010), Nonprocessive motor dynamics at the microtubule membrane tube interface, Biophysical Journal 98(1): 93-100.
- Semrau S. & Schmidt T. (2009), Membrane-heterogeneity - from lipid domains to curvature effects, 5: 3174-3186.
- Koopmans W.J.A., Buning R., Schmidt T. & Noort S.J.T. van (2009), spFRET using alternating excitation and FCS reveals progressive DNA unvwrapping in nucleosomes, Biophysical Journal 97: 195-204.
- Jensenius T.M.H., Klein D.C.G., Hecke M.L. van, Oosterkamp T.H., Schmidt T. & Jensenius J.C. (2009), Mannan-binding lectin: Structure, oligomerization, and flexibility studied by Atomic Force Microscopy, Journal of Molecular Biology/JMB Online 391(1): 246-259.
- Schaaf M.J.M., Koopmans W., Meckel T.M., Noort S.J.T. van, Snaar B.E., Schmidt T. & Spaink H.P. (2009), Single-molecule microscopy reveals membrane microdomain organization of cells in a living vertebrate, Biophysical Journal 97(4): 1206-1214.
- Paulo P.M.R., Gaiduk A., Kulzer F.M., Krens S.F.G., Spaink H.P., Schmidt T. & Orrit M.A.G.J. (2009), Photothermal correlation spectroscopy of gold nanoparticles in solution, The Journal of Physical Chemistry Part C 113(27): 11451-11457.
- Semrau S., Idema T., Schmidt T. & Storm C. (2009), Membrane-mediated interactions measured using membrane domains, Biophysical Journal 96: 4906-4915.
- Keijzer S. de, Snaar-Jagalska B.E., Spaink H.P. & Schmidt T. (2008), Single molecule imaging of cellular signaling. In: Rigler R. & Vogel H. (Eds.), Single Molecules and Nanotechnology. Biophysics no. 12. Berlin, Heidelberg: Springer-Verlag. 107-129.
- Kulzer F.M., Laurens N., Besser J.C., Schmidt T., Orrit M.A.G.J. & Spaink H.P. (2008), Photothermal detection of individual gold nanoparticles: perspectives for high-throughput screening, ChemPhysChem 9: 1761-1766.
- Semrau S., Idema T., Holtzer L., Schmidt T. & Storm C. (2008), Accurate determination of elastic parameters for multicomponent membranes, Physical Review Letters 100(8): 088101.
- Koopmans W., Schmidt T. & Noort S.J.T. van (2008), Nucleosome immobilization strategies for single-pair FRET microscopy, ChemPhysChem 9: 2002-2009.
- Keijzer S. de, Sergé A., Hemert F. van, Lommerse P., Lamers G.E.M., Spaink H.P., Schmidt T. & Snaar-Jagalska B.E. (2008), A spatially restricted increase in receptor mobility is involved in directional sensing during Dictyostelium discoideum chemotaxis, Journal of Cell Science 121(10): 1750-1757.
- Krens S.F.G., He S., Lamers G.E.M., Meijer A.H., Bakkers J., Schmidt T., Spaink H.P. & Snaar-Jagalska B.E. (2008), Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation, Developmental Biology 319(2): 370-383.
- Semrau S. & Schmidt T. (2007), Particle image correlation spectroscopy (PICS). Retrieving nanometer-scale correlations from high-density single-molecule position data, Biophysical Journal 92: 613-621.
- Semrau S. & Schmidt T. (2007), Particle image correlation spectroscopy (PICS): retrieving nanometer-scale correlations from high-density single-molecule position data, Biophysical Journal 92(2): 613-621.
- Haupt B.J., Osbourn M., Spanhoff R., Keijzer S. de, Müller-Taubenberger A., Snaar-Jagalska B.E. & Schmidt T. (2007), Asymmetric elastic properties of Dictyostelium discoideum in relation to chemotaxis, Langmuir 23(18): 9352-9357.
- Lommerse P., Vastenhoud K., Pirinen N.J., Magee A.I., Spaink H.P. & Schmidt T. (2006), Single-molecule diffusion reveals similar mobility for the Lck, H-ras, and K-ras membrane anchors, Biophysical Journal 91(3): 1090-1097.
- Lommerse P.H., Snaar-Jagalska B.E., Spaink H.P. & Schmidt T. (2005), Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation, Journal of Cell Science 118(9): 1799-1809.
- Schmauder R., Librizzi R., Canters G.W., Schmidt T. & Aartsma T.J. (2005), The oxidation state of a protein observed molecule-by-molecule, ChemPhysChem 6(7): 1381-1386.
- Schmauder R., Alagaratnam S., Chan C., Schmidt T., Canters G.W. & Aartsma T.J. (2005), Sensitive detection of the redox state of copper proteins using fluorescence, Journal of Biological Inorganic Chemistry 10(6): 683-687.
- Hemert M.J. van, Niemantsverdriet M., Schmidt T., Backendorf C.M.P. & Spaink H.P. (2004), Isoform-specific differences in rapid nucleocytoplasmic shuttling cause distinct subcellular distributions in 14-3-3-σ and 14-3-3-ζ, Journal of Cell Science 117(8): 1411-1420.
- Blab G.A., Schmidt T. & Nilsson M. (2004), Homogeneous detection of single rolling circle replication products, Analytical Chemistry 76: 495-498.
- Gradinaru C.C., Martinson P., Aartsma T.J. & Schmidt T. (2004), Simultaneous atomic-force and two-photon fluorescence imaging of biological specimens in vivo, Ultramicroscopy 99(4): 235-245.
- Lommerse P.H., Blab G.A., Cognet L., Harms G.S., Snaar B.E., Spaink H.P. & Schmidt T. (2004), Single-molecule imaging of the h-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane, Biophysical Journal 86(1): 609-616.
- Blab G.A., Oellerich S., Schumm R. & Schmidt T. (2004), Simultaneous wide-field imaging and spectroscopy of localized fluorophores, Optics Letters 29: 727-729.
- Lommerse P., Spaink H.P. & Schmidt T. (2004), In vivo plasma membrane organization: results of biophysical approaches, Biochimica et Biophysica Acta 1664(2): 119-131.
- Schmauder R., Schmidt T., Abrahams J.P. & Kuil M.E. (2003), Screening crystallisation conditions using fluorescence correlation spectroscopy, Acta Crystallographica Section D Structural Biology D58: 1536-1541.
- Blab G.A., Lommerse P.H.M., Cognet L., Harms G.S. & Schmidt T. (2001), Two-photon excitation action cross-sections of the autofluorescent proteins, Chemical Physics Letters 350(1-2): 71-77.
- Trabesinger W., Hecht B., Wild U.P., Schutz G.J., Schindler H. & Schmidt T. (2001), Statistical analysis of single-molecule colocalization assays, Analytical Chemistry 73(6): 1100-1105.
- Harms G.S., Cognet L., Lommerse P.H.M., Blab G.A., Kahr H., Gamsjager R., Spaink H.P., Soldatov N.M., Romanin C. & Schmidt T. (2001), Single-molecule imaging of L-type Ca2+ channels in live cells, Biophysical Journal 81(5): 2639-2646.
- Harms G.S., Cognet L., Lommerse P.H.M., Blab G.A. & Schmidt T. (2001), Autofluorescent proteins in single-molecule research: Applications to live cell imaging microscopy, Biophysical Journal 80(5): 2396-2408.
- Cognet L., Harms G.S., Blab G.A., Lommerse P.H.M. & Schmidt T. (2000), Simultaneous dual-color and dual-polarization imaging of single molecules, Applied Physics Letters 77(24): 4052-4054.
- Kepplinger K.J., Kahr H., Förstner G., Sonnleitner M., Schindler H., Schmidt T., Groschner K., Soldatov N.M. & Romanin C. (2000), A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels, FEBS Letters 477(3): 161-169.
- Sonnleitner M., Schutz G.J. & Schmidt T. (1999), Imaging individual molecules by two-photon excitation, Chemical Physics Letters 300(1-2): 221-226.
- Trabesinger W., Schutz G.J., Gruber H.J., Schindler H. & Schmidt T. (1999), Detection of individual oligonucleotide pairing by single-molecule microscopy, Analytical Chemistry 71(1): 279-283.
- Schmidt T., Hinterdorfer P. & Schindler H. (1999), Microscopy for recognition of individual biomolecules, Microscopy Research and Technique 44(5): 339-346.
- Harms G.S., Sonnleitner M., Schütz G.J., Gruber H.J. & Schmidt T. (1999), Single-molecule anisotropy imaging, Biophysical Journal 77(5): 2864-2870.
- Schütz G.J., Trabesinger W. & Schmidt T. (1998), Direct observation of ligand colocalization on individual receptor molecules, Biophysical Journal 74(5): 2223-2226.
- Schutz G.J., Gruber H.J., Schindler H. & Schmidt T. (1997), Fluorophores for single molecule microscopy, Journal of Luminescence 72-74: 18-21.
- Schütz G.J., Schindler H. & Schmidt T. (1997), Single-molecule microscopy on model membranes reveals anomalous diffusion, Biophysical Journal 73(2): 1073-1080.
- Schutz G.J., Schindler H. & Schmidt T. (1997), Imaging single-molecule dichroism, Optics Letters 22(9): 651-653.
- Straat D.A. van de, Baak J., Brom H.B., Schmidt T. & Volker S. (1996), Low-temperature specific heat of rare-earth-doped silicate glasses, Physical Review B: Condensed Matter 53(5): 2179-2182.
- Schmidt T., Schutz G.J., Gruber H.J. & Schindler H. (1996), Local stoichiometries determined by counting individual molecules, Analytical Chemistry 68(24): 4397-4401.
- Schmidt T., Schütz G.J., Baumgartner W., Gruber H.J. & Schindler H. (1996), Imaging of single molecule diffusion, Proceedings of the National Academy of Sciences 93(7): 2926-2929.
- Schmidt T., Schutz G.J., Baumgartner W., Gruber H.J. & Schindler H. (1995), Characterization of photophysics and mobility of single molecules in a fluid lipid-membrane, Journal of Physical Chemistry 99(49): 17662-17668.
- Schmidt T., Baak J., Straat D.A. van de, Brom H. & Volker S. (1994), Temperature-dependence of optical-line widths and specific-heat of rare-earth-doped silicate-glasses, Journal of Luminescence 58(1-6): 180-183.
- Schmidt T., MacFarlane R.M. & Volker S. (1994), Persistent and transient spectral hole-burning in Pr3+-doped, and Eu3+-doped silicate-glasses, Physical Review B: Condensed Matter 50(21): 15707-15718.
- Schmidt T., Baak J., Straat D.A. van de, Brom H.B. & Völker S. (1993), Temperature dependence of optical linewidths and specific heat of rare-earth-doped silicate glasses, Physical Review Letters 71(18): 3031-3034.
- Laan H. van der, Caro C. de, Schmidt T., Visschers R.W., Grondelle R. van, Fowler G.J.S., Hunte C.N. & Volker S. (1993), Excited-state dynamics of mutated antenna complexes of purple bacteria studied by hole-burning , Chemical Physics Letters 212(6): 569-580.
- Wannemacher R., Smorenburg H.E., Schmidt T. & Volker S. (1992), Transient hole-burning with a diode-laser - a study of bacteriochlorophyll-A in a glass on a microsecond time scale , Journal of Luminescence 53(1-6): 266-270.
- Laan H. van der, Smorenburg H.E., Schmidt T. & Volker S. (1992), Permanent hole burning with a diode laser: excited-state dynamics of bacteriochlorophyll in glasses and micelles, Journal of the Optical Society of America B: Optical Physics 9(6): 931-940.
- Laan H. van der, Schmidt T. & Volker S. (1991), Energy-transfer and dynamics of photosynthetic antenna complexes and biological model systems - A study by photochemical hole-burning, Journal of Luminescence 48-49(part 1): 199-203.
- Zaag P.J. van der, Schokker B.C., Schmidt T. & Volker S. (1991), Spectral hole-burning on inorganic glasses doped with the rare-earth ions Pr3+ and Eu3+, Radiation Effects and Defects in Solids 119(1): 361-362.
- Zaag P.J. van der, Schmidt T., Laan H. van der, Visser A. & Volker S. (1990), Photoreactive disordered-systems studied by permanent and transient hole-burning , Molecular Crystals and Liquid Crystals 183(1): 105-118.
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