M Malessy
Professor Nerve Surgery
- Name
- Prof.dr. M.J.A. Malessy
- Telephone
- +31 71 526 3035
- m.j.a.malessy@lumc.nl
- ORCID iD
- 0000-0003-1936-3664
Martijn Malessy is Professor of Nerve Surgery and head of the Nerve Center at the Leiden University Medical Center, the Netherlands. He is clinical-scientific advisor for nerve regeneration research at the Netherlands Insitute for Neuroscience in Amsterdam. He is also a member of the Peripheral Nerve Surgery Committee of the World Federation of Neurosurgical Societies. He has a vast experience in the nerve surgical treatment of complex nerve lesions, nerve tumours, complex nerve entrapment syndromes and neuropathic pain due to a nerve lesion.
More information about M Malessy
See also
Nerve surgery
Nerve surgery includes the area where the function of nerves is impaired by an injury, compression or tumor or causes pain syndromes. At the Nerve Center, Malessy coordinates the diagnosis, indication, timing and manner of surgical intervention that takes place in a multidisciplinary context and that is relevant for optimal care. All modern nerve surgical techniques are performed by him and his team, including the attachment of nerves, nerve transplants and nerve diversion operations. Nerve surgical treatments are constantly being developed and new techniques are being disseminated through scientific publications. In education, the neurosurgical anatomy, the pathophysiology of nerve damage and recovery and the surgical treatment are central. In addition, Malessy provides training for future neurosurgeons and international fellows. He is involved in basic scientific research into nerve regeneration and pain. He has set up the PainLess Foundation which aims to promote medical scientific research in the field of pain, nerve damage and recovery.
Academic career
After completing secondary school at the Kennemer Lyceum in Overveen, Malessy studied medicine in Ghent (Belgium) and Leiden respectively. He was trained as a Neurosurgeon at the LUMC and at the Onze Lieve Vrouwe Gasthuis in Amsterdam. In 1995 he was registered as a consultant and became a member of the Neurosurgical Staff of the LUMC. In 1999 he obtained his PhD in Leiden with a thesis entitled 'Brachial Plexus Surgery: Factors affecting functional recovery'. He was appointed Professor of Nerve Surgery on 1 January 2011. The title of his inaugural lecture was "If not now, when?". Since 2009 he has been Associate Editor in the peripheral nerves section of the trade journal "Neurosurgery". Between 2009 and 2013 he was co-chairman of the Peripheral Nerve Surgery Committee of the World Federation of Neurosurgical Societies. Between 2011 and 2013 he was the chairman of the Sunderland Society. In 2013 he was Visiting Interdisciplinary Professor in Peripheral Nerve Surgery, Mayo Clinic, Rochester, Minnesota. In 2016-2017 he was the President of the American Society for Peripheral Nerve.
Prizes and honourable appointments
He received the H. Verbiest prize of the Dutch Society of Neurosurgeons for scientific work on the brachial plexus. In 2014 he was the awarded Kline Lecturer at the meeting of the American Association of Neurological Surgeons in San Fransisco.
Professor Nerve Surgery
- Faculteit Geneeskunde
- Divisie 3
- Neurochirurgie
- Socolovsky, M.; Barillaro, K.; Bonilla, G.; Masi, G. di & Malessy, M. (2023), Nerve transfers for brachial plexus injuries, Journal of Neurosurgery 138(5): 1419-1425.
- Buitenhuis, S.M.; Pondaag, W.; Wolterbeek, R. & Malessy, M.J.A. (2023), Tactile perception of the hand in children with an upper neonatal brachial plexus palsy, Archives of Physical Medicine and Rehabilitation 104(6): 872-877.
- Rodriguez, A.G.; Carrazana, M.S.; Tanty, C.R.; Malessy, M.J.A.; Fuentes, G. & Cruz, L.J. (2023), Smart Polymeric Micelles for Anticancer Hydrophobic Drugs, Cancers 15(1).
- Steenbeek, E.D.; Pondaag, W.; Tannemaat, M.R.; Zwet, E.W. van; Malessy, M.J.A. & Groen, J.L. (2023), Optimal timing of needle electromyography to diagnose lesion severity in traumatic radial nerve injury, Muscle & Nerve 67(4).
- Kleijwegt, M.C.; Wever, C.; Hensen, E.F.; Jansen, J.C.; Koot, R.W. & Malessy, M.J.A. (2023), Reestablishment of the smile after hypoglossal-facial nerve transfer, Journal of Neurological Surgery Part B: Skull Base.
- Socolovsky, M.; Masi, G. di; Bonilla, G.; Lovaglio, A.; Battaglia, D.; Rosler, R. & Malessy, M. (2023), Brain plasticity in neonatal brachial plexus palsies, Child's Nervous System 40.
- Sarac, C.; Nelissen, R.G.H.H.; Holst, M. van der; Malessy, M.J.A. & Pondaag, W. (2022), Differences in the perspectives of functioning and health in the ICF model between patients with brachial plexus birth injury and their parents versus healthcare professionals, Disability and Rehabilitation 45(11).
- Breemer, M.C.; Notenboom, R.G.E. & Malessy, M.J.A. (2022), Letter to the Editor concerning "Clinical anatomy of the lumbar sinuvertebral nerve with regard to discogenic low back pain and review of literature" by Sara Quinones et al. (Eur Spine J [2021]; 30(10):2999-3008).
- Kleijwegt, M.C.; Koot, R.W.; Mey, A.G.L. van der; Hensen, E.F. & Malessy, M.J.A. (2022), The combined TL-RS approach, Journal of Neurological Surgery Part B: Skull Base 84(3).
- Pondaag, W.; Groen, J.L. & Malessy, M.J.A. (2022), Endoscopic harvest of sural nerve for grafting in infants with brachial plexus birth injury.
- Groen, J.L.; Moghadasi, S.; Spruijt, L.; Korpershoek, E.; Ierland, Y. van; Wezel, J.T. van; Duinen, S. van; Malessy, M.J.A. & Oberstein, S.A.J.L. (2022), Neurofibromas in LZTR1 schwannomatosis.
- Pondaag, W. & Malessy, M. (2022), Re: Cay et al. Quotation errors related to the distal radius acute fracture fixation trial paper. J Hand Surg Eur. Epub ahead of print 24 March 2021. DOI: 10.1177/17531934211002985 Reply.
- Boer, N.P. de; Bohringer, S.; Koot, R.W.; Malessy, M.J.A.; Mey, A.G.L. van der; Jansen, J.C. & Hensen, E.F. (2022), A prediction model for recurrence after translabyrinthine surgery for vestibular schwannoma, European Archives of Oto-Rhino-Laryngology 279.
- Pondaag, W. & Malessy, M.J.A. (2022), Re: Oberlin C. Rethinking surgical strategy in the management of obstetrical palsy. J Hand Surg Eur. 2021, 46: 705-7.
- Chalaki, M.; Cruz, L.J.; Neerven, S.G.A. van; Verhaagen, J.; Dahan, A. & Malessy, M.J.A. (2022), Molecular changes in the dorsal root ganglion during the late phase of peripheral nerve injury-induced pain in rodents: a systematic review, Anesthesiology 136(2): 362-388.
- Ulmann, E.T.E.; Malessy, M.J.A.; Nagels, J. & Pondaag, W. (2022), Shoulder internal rotation contracture formation in surgically managed C5, C6 brachial plexus birth injuries neurotmetic lesions fare worse than avulsions, Journal of Bone and Joint Surgery 104(22): 2008-2015.
- Boer, N.P. de; Bohringer, S.; Koot, R.W.; Malessy, M.J.A.; Mey, A.G.L. van der; Jansen, J.C. & Hensen, E.F. (2022), Response to a letter to the editor "A prediction model for recurrence after translabyrinthine surgery for vestibular schwannoma: towards personalized postoperative surveillance".
- Pondaag, W.; Groen, J.L. & Malessy, M.J.A. (2022), Endoscopic harvest of sural nerve for grafting in infants with brachial plexus birth injury.
- Pondaag, W.; Groen, J.L. & Malessy, M.J.A. (2021), Nerve repair in brachial plexus birth injury.
- Boer, N.P. de; Koot, R.W.; Jansen, J.C.; Bohringer, S.; Crouzen, J.A.; Mey, A.G.L. van der; Malessy, M.J.A. & Hensen, E.F. (2021), Prognostic factors for the outcome of translabyrinthine surgery for vestibular schwannomas, Otology and Neurotology 42(3): 475-482.
- Socolovsky, M. & Malessy, M. (2021), Brain changes after peripheral nerve repair: limitations of neuroplasticity, Journal of Neurosurgical Sciences 65(4): 421-430.
- Pondaag, W. & Malessy, M.J.A. (2021), Letter about a Published Paper, The Journal of Hand Surgery: British & European Volume.
- Breemer, M.C.; Malessy, M.J.A. & Notenboom, R.G.E. (2021), Origin, branching pattern, foraminal and intraspinal distribution of the human lumbar sinuvertebral nerves, The Spine Journal 22(3).
- Buitenhuis, S.M.; Pondaag, W.; Wolterbeek, R. & Malessy, M.J.A. (2021), Gripforce reduction in children with an upper neonatal brachial plexus palsy, Journal of Rehabilitation Medicine 53(8).
- Vliet, A.C. van; Lee, J.; Poel, M. van der; Mason, M.R.J.; Noordermeer, J.N.; Fradkin, L.G.; Tannemaat, M.R.; Malessy, M.J.A.; Verhaagen, J. & Winter, F. de (2021), Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury, PLoS ONE 16(4).
- Eggers, R.; Winter, F. de; Tannemaat, M.R.; Malessy, M.J.A. & Verhaagen, J. (2020), GDNF gene therapy to repair the injured peripheral nerve, Frontiers in Bioengineering and Biotechnology 8.
- Malessy, M.J.A.; Eekhof, J. & Pondaag, W. (2020), Meralgia paresthetica: what to do? Response.
- Pondaag, W. & Malessy, M.J.A. (2020), Evidence that nerve surgery improves functional outcome for obstetric brachial plexus injury, Journal of Hand Surgery (European Volume) 46(3).
- Kleijwegt, M.; Bettink, F.; Malessy, M.; Putter, H. & Mey, A. van der (2020), Clinical predictors leading to change of initial conservative treatment of 836 vestibular schwannomas, Journal of Neurological Surgery Part B: Skull Base 81(1): 15-21.
- Groen, J.L.; Pondaag, W. & Malessy, M. (2019), Reoperation for recurrent or persistent ulnar nerve symptoms, Journal of Neurosurgery 130(4): 1403-1404.
- Eggers, R.; Winter, F. de; Hoyng, S.A.; Hoeben, R.C.; Malessy, M.J.A.; Tannemaat, M.R. & Verhaagen, J. (2019), Timed GDNF gene therapy using an immune-evasive gene switch promotes long distance axon regeneration, Brain 142: 295-311.
- Socolovsky, M.; Malessy, M.; Bonilla, G.; Masi, G. di; Conti, M.E. & Lovaglio, A. (2019), Phrenic to musculocutaneous nerve transfer for traumatic brachial plexus injuries: analyzing respiratory effects on elbow flexion control, Journal of Neurosurgery 131(1): 165-174.
- Straaten, T.F.K. van der; Netten, A.P.; Boermans, P.P.B.M.; Briaire, J.J.; Scholing, E.; Koot, R.W.; Malessy, M.J.A.; Mey, A.G.L. van der; Verbist, B.M. & Frijns, J.H.M. (2019), Pediatric Auditory Brainstem Implant Users Compared With Cochlear Implant Users With Additional Disabilities, Otology and Neurotology 40(7): 936-945.
- Malessy, M.J.A.; Eekhof, J. & Pondaag, W. (2019), Dynamic decompression of the lateral femoral cutaneous nerve to treat meralgia paresthetica: technique and results, Journal of Neurosurgery 131(5): 1552-1560.
- Pondaag, W.; Driest, F.Y. van; Groen, J.L. & Malessy, M.J.A. (2019), Early nerve repair in traumatic brachial plexus injuries in adults: treatment algorithm and first experiences, Journal of Neurosurgery 130(1): 172-178.
- Hilgersom, N.F.J.; Deurzen, D.F.P. van; Gerritsma, C.L.E.; Heide, H.J.L. van der; Malessy, M.J.A.; Eygendaal, D. & Bekerom, M.P.J. van den (2018), Nerve injuries do occur in elbow arthroscopy, Knee Surgery, Sports Traumatology, Arthroscopy 26(1): 318-324.
- Datema, M.; Tannemaat, M.R.; Hoitsma, E.; Zwet, E.W. van; Smits, F.; Dijk, J.G. van & Malessy, M.J.A. (2018), Outcome of Carpal Tunnel Release and the Relation With Depression, Journal of Hand Surgery (American Volume) 43(1): 16-23.
- Pondaag, W. & Malessy, M.J.A. (2018), Outcome assessment for Brachial Plexus birth injury. Results from the iPluto world-wide consensus survey, Journal of Orthopaedic Research 36(9): 2533-2541.
- Malessy, M.J.A.; Boer, R. de; Romero, I.M.; Eekhof, J.L.A.; Zwet, E.W. van; Kliot, M.; Dahan, A. & Pondaag, W. (2018), Predictive value of a diagnostic block in focal nerve injury with neuropathic pain when surgery is considered, PLoS ONE 13(9).
- Buitenhuis, S.M.; Pondaag, W.; Wolterbeek, R. & Malessy, M.J.A. (2018), Sensibility of the Hand in Children With Conservatively or Surgically Treated Upper Neonatal Brachial Plexus Lesion, Pediatric Neurology 86: 57-62.
- Buitenhuis, S.M.; Pondaag, W.; Wolterbeek, R. & Malessy, M.J.A. (2018), Hand Sensibility in Healthy Young Children, Pediatric Neurology 86: 52-56.
- Duijnisveld, B.J.; Wijlen-Hempel, M.S. van; Hogendoorn, S.; Boer, K.S. de; Malessy, M.J.A.; Keurentjes, J.C.; Nagels, J. & Nelissen, R.G.H.H. (2017), Botulinum Toxin Injection for Internal Rotation Contractures in Brachial Plexus Birth Palsy. A Minimum 5-Year Prospective Observational Study, Journal of Pediatric Orthopaedics 37(3): E209-E215.
- Anguelova, G.V.; Rombouts, S.A.R.B.; Dijk, J.G. van; Buur, P.F. & Malessy, M.J.A. (2017), Increased brain activation during motor imagery suggests central abnormality in Neonatal Brachial Plexus Palsy, Neuroscience Research.
- Anguelova, G.V.; Vlugt, E. de; Vardy, A.N.; Zwet, E.W. van; Dijk, J.G. van; Malessy, M.J.A. & Groot, J.H. de (2017), Cocontraction measured with short-range stiffness was higher in obstetric brachial plexus lesions patients compared to healthy subjects.
- Soulier, G.; Leeuwen, B.M. van; Putter, H.; Jansen, J.C.; Malessy, M.J.A.; Benthem, P.P.G. van; Mey, A.G.L. van der & Stiggelbout, A.M. (2017), Quality of Life in 807 Patients with Vestibular Schwannoma: Comparing Treatment Modalities, Otolaryngology - Head and Neck Surgery 157(1): 92-98.
- Verweij, J.P.; Hof, K.S. van; Malessy, M.J.A. & Merkesteyn, R. van (2017), Neuropathic Pain Due to Iatrogenic Lingual Nerve Lesion: Nerve Grafting to Reduce Otherwise Untreatable Pain, Journal of Craniofacial Surgery 28(2): 496-500.
- Tannemaat, M.R.; Datema, M.; Dijk, J.G. van; Midha, R. & Malessy, M.J.A. (2017), In Reply: Decompressive Surgery for Diabetic Neuropathy: Waiting for Incontrovertible Proof, Neurosurgery 81(3).
- Malheiros, J.A.; Cancado, S.A.V.; Belo, J.T.A.; Garcia, L.A.O.; Oliveira, M.M. de & Malessy, M.J.A. (2017), Endoscopic Sural Nerve Removal in Obstetric Brachial Plexopathy Using Basic Endoscopy Instruments: Technical Note, Brazilian Neurosurgery 36(2): 75-79.
- Socolovsky, M.; Malessy, M.; Lopez, D.; Guedes, F. & Flores, L. (2017), Current concepts in plasticity and nerve transfers: relationship between surgical techniques and outcomes, Neurosurgical focus 42(3).
- Gent, J.A.N. van; Datema, M.; Groen, J.L.; Pondaag, W.; Eekhof, J.L.A. & Malessy, M.J.A. (2017), Anterior subcutaneous transposition for persistent ulnar neuropathy after neurolysis, Neurosurgical focus 42(3).
- Datema, M.; Hoitsma, E.; Roon, K.I.; Malessy, M.J.A.; Dijk, J.G. van & Tannemaat, M.R. (2016), The Tinel sign has no diagnostic value for nerve entrapment or neuropathy in the legs, Muscle and Nerve 54(1): 25-30.
- Eggers, R.; Tannemaat, M.R.; Winter, F. de; Malessy, M.J.A. & Verhaagen, J. (2016), Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion, European Journal of Neuroscience 43(3): 318-335.
- Fraiman, D.; Miranda, M.F.; Erthal, F.; Buur, P.F.; Elschot, M.; Souza, L.; Rombouts, S.A.R.B.; Schimmelpenninck, C.A.; Norris, D.G.; Malessy, M.J.A.; Galves, A. & Vargas, C.D. (2016), Reduced functional connectivity within the primary motor cortex of patients with brachial plexus injury, NeuroImage: Clinical 12: 277-284.
- (2016), Sensory Deficit in Conservatively Treated Neonatal Brachial Plexus Palsy Patients, Pediatric Neurology.
- Rajiv Midha, MD, PhD, Department of Clinical Neurosciences, University of Calgary, Alberta & Canada (2016), Decompressive Surgery for Diabetic Neuropathy: Waiting for Incontrovertible Proof.
- Verstegen, M.J.T.; Tummers, Q.R.J.G.; Schutte, P.J.; Pereira, A.M.; Furth, W.R. van; Velde, C.J.H.V. de; Malessy, M.J.A. & Vahrmeijer, A.L. (2016), Intraoperative Identification of a Normal Pituitary Gland and an Adenoma Using Near-Infrared Fluorescence Imaging and Low-Dose Indocyanine Green, Operative Neurosurgery 12(3): 260-267.
- Kleijwegt, M.C.; Mey, A.G.L. van der; Wiggers-deBruine, F.T.; Malessy, M.J.A. & Osch, M.J.P. van (2016), Perfusion magnetic resonance imaging provides additional information as compared to anatomical imaging for decision-making in vestibular schwannoma, European Journal of Radiology Open 3: 127-133.
- Anguelova, G.V.; Malessy, M.J.A.; Buitenhuis, S.M.; Zwet, E.W. van & Dijk, J.G. van (2016), Impaired Automatic Arm Movements in Obstetric Brachial Plexus Palsy Suggest a Central Disorder, Journal of Child Neurology 31(8): 1005-1009.
- Pondaag, W. & Malessy, M.J.A. (2015), Re: Pondaag W, Malessy MJA. Intercostal and pectoral nerve transfers to reinnervate the biceps muscle in obstetric brachial plexus lesions. J Hand Surg Eur. 2014, 39: 647-52 Reply, Journal of Hand Surgery (European Volume) 40(3): 325-326.
- Hoyng, S.A.; Winter, F. de; Tannemaat, M.R.; Blits, B.; Malessy, M.J.A. & Verhaagen, J. (2015), Gene therapy and peripheral nerve repair: a perspective, Frontiers in Molecular Neuroscience 8.
- Vliet, A.C. van; Tannemaat, M.R.; Duinen, S.G. van; Verhaagen, J.; Malessy, M.J.A. & Winter, F. de (2015), Human Neuroma-in-Continuity Contains Focal Deficits in Myelination, Journal of Neuropathology and Experimental Neurology 74(9): 901-911.
- Hoyng, S.A.; Winter, F. de; Gnavi, S.; Egmond, L. van; Attwell, C.L.; Tannemaat, M.R.; Verhaagen, J. & Malessy, M.J.A. (2015), Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1-9 and lentiviral vectors, Gene Therapy 22(10): 767-780.
- Tse, R.; Kozin, S.H.; Malessy, M.J. & Clarke, H.M. (2015), International Federation of Societies for Surgery of the Hand Committee Report: The Role of Nerve Transfers in the Treatment of Neonatal Brachial Plexus Palsy, Journal of Hand Surgery (American Volume) 40(6): 1246-1259.
- Amrami, K.K.; Kliot, M.; Malessy, M.J.A. & Spinner, R.J. (2015), Imaging of peripheral nerves INTRODUCTION, Neurosurgical focus 39(3).
- Anguelova, G.V.; Malessy, M.J.A.; Zwet, E.W. van & Dijk, J.G. van (2014), Extensive motor axonal misrouting after conservative treatment of obstetric brachial plexus lesions, Developmental Medicine and Child Neurology 56(10): 984-989.
- Hoyng, S.A.; Gnavi, S.; Winter, F. de; Eggers, R.; Ozawa, T.; Zaldumbide, A.; Hoeben, R.C.; Malessy, M.J.A. & Verhaagen, J. (2014), Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve, Gene Therapy 21(6): 549-557.
- Pondaag, W. & Malessy, M.J.A. (2014), Neonatal brachial plexus palsy, Journal of Neurosurgery: Pediatrics 14(5): 555-557.
- Petrova, I.M.; Malessy, M.J.; Verhaagen, J.; Fradkin, L.G. & Noordermeer, J.N. (2014), Wnt Signaling through the Ror Receptor in the Nervous System, Molecular Neurobiology 49(1): 303-315.
- Pondaag, W. & Malessy, M.J.A. (2014), Intercostal and pectoral nerve transfers to re-innervate the biceps muscle in obstetric brachial plexus lesions.
- Pondaag, W. & Malessy, M.J.A. (2014), Neurolysis and upper trunk brachial plexus birth palsy, Journal of Neurosurgery: Pediatrics 14(3): 322-324.
- Hoyng, S.A.; Winter, F. de; Gnavi, S.; Boer, R. de; Boon, L.I.; Korvers, L.M.; Tannemaat, M.R.; Malessy, M.J.A. & Verhaagen, J. (2014), A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF, Experimental Neurology 261: 578-593.
- Ruiter, G.C.W. de; Spinner, R.J.; Verhaagen, J. & Malessy, M.J.A. (2014), Misdirection and guidance of regenerating axons after experimental nerve injury and repair A review, Journal of Neurosurgery 120(2): 493-501.
- Malessy, M.J.A. & Pondaag, W. (2014), Neonatal Brachial Plexus Palsy with Neurotmesis of C5 and Avulsion of C6, Journal of Bone and Joint Surgery, American Volume 96A(20).
- Buckle, T.; Verbist, B.; Balm, F.; Malessy, M.; Buchem, M. van & Leeuwen, F. van (2014), Feasibility of nerve specific MRI for surgical planning and virtual surgery in the head and neck area, Journal of Nuclear Medicine 55.
- Pondaag, W. & Malessy, M.J.A. (2014), The Evidence for Nerve Repair in Obstetric Brachial Plexus Palsy Revisited, BioMed Research International.
- Socolovsky, M.; Masi, G. di; Bonilla, G. & Malessy, M. (2014), Spinal to accessory nerve transfer in traumatic brachial plexus palsy: is body mass index a predictor of outcome?, Acta Neurochirurgica 156(1): 159-163.
- Duijnisveld, B.J.; Sarac, C.; Malessy, M.J.A.; Vlieland, T.P.M.V.; Nelissen, R.G.H.H. & ICF Brachial Plexus Advisory Board (2013), Developing core sets for patients with obstetric brachial plexus injury based on the International Classification of Functioning, Disability and Health, Bone and Joint Research 2(6): 116-121.
- Eggers, R.; Winter, F. de; Hoyng, S.A.; Roet, K.C.D.; Ehlert, E.M.; Malessy, M.J.A.; Verhaagen, J. & Tannemaat, M.R. (2013), Lentiviral Vector-Mediated Gradients of GDNF in the Injured Peripheral Nerve: Effects on Nerve Coil Formation, Schwann Cell Maturation and Myelination, PLoS ONE 8(8).
- Winter, F. de; Hoyng, S.; Tannemaat, M.; Eggers, R.; Mason, M.; Malessy, M. & Verhaagen, J. (2013), Gene therapy approaches to enhance regeneration of the injured peripheral nerve, European Journal of Pharmacology 719(1-3): 145-152.
- Sarac, C.; Bastiaansen, E.; Holst, M. van der; Malessy, M.J.A.; Nelissen, R.G.H.H. & Vliet Vlieland, T.P.M. (2013), Concepts of functioning and health important to children with an obstetric brachial plexus injury: a qualitative study using focus groups, Developmental Medicine and Child Neurology 55(12): 1136-1142.
- Vries, M. de; Briaire-de Bruijn, I.; Malessy, M.J.A.; Bruine, S.F.T. de; Mey, A.G.L. van der & Hogendoorn, P.C.W. (2013), Tumor-Associated Macrophages Are Related to Volumetric Growth of Vestibular Schwannomas, Otology and Neurotology 34(2): 347-352.
- Petrova, I.M.; Lahaye, L.L.; Martianez, T.; Jong, A.W.M. de; Malessy, M.J.; Verhaagen, J.; Noordermeer, J.N. & Fradkin, L.G. (2013), Homodimerization of the Wnt Receptor DERAILED Recruits the Src Family Kinase SRC64B, Molecular and Cellular Biology 33(20): 4116-4127.
- Vries, M. de; Briaire-de Bruijn, I.; Malessy, M.J.A.; Bruine, S.F.T. de; Mey, A.G.L. van der & Hogendoorn, P.C.W. (2013), Tumor-associated macrophages are related to volumetric growth of vestibular schwannomas, Otology and Neurotology.
- Vries, M. de; Briaire-de Bruijn, I.; Cleton-Jansen, A.M.; Malessy, M.J.A.; Mey, A.G.L. van der & Hogendoorn, P.C.W. (2013), Mutations affecting BRAF, EGFR, PIK3CA, and KRAS are not associated with sporadic vestibular schwannomas, Virchows Archiv 462(2): 211-217.
- Anguelova, G.V.; Malessy, M.J.A. & Dijk, J.G. van (2013), A cross-sectional study of hand sensation in adults with conservatively treated obstetric brachial plexus lesion, Developmental Medicine and Child Neurology 55(3): 257-263.
- Vries, M. de; Hogendoorn, P.C.W.; Briaire-de Bruyn, I.; Malessy, M.J.A. & Mey, A.G.L. van der (2012), Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas, Virchows Archiv 460.
- Buitenhuis, S.; Wijlen-Hempel, R.S. van; Pondaag, W. & Malessy, M.J.A. (2012), Obstetric brachial plexus lesions and central developmental disability, Early Human Development 88(9): 731-734.
- Vries, M. de; Hogendoorn, P.C.W.; Briaire-de Bruyn, I.; Malessy, M.J.A. & Mey, A.G.L. van der (2012), Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas, Virchows Archiv 460(6): 629-636.
- Dijk, J.G. van; Pondaag, W.; Buitenhuis, S.M.; Zwet, E.W. van & Malessy, M.J.A. (2012), Needle electromyography at 1 month predicts paralysis of elbow flexion at 3 months in obstetric brachial plexus lesions, Developmental Medicine and Child Neurology 54(8): 753-758.
- Boer, R. de; Borntraeger, A.; Knight, A.M.; Hebert-Blouin, M.N.; Spinner, R.J.; Malessy, M.J.A.; Yaszemski, M.J. & Windebank, A.J. (2012), Short- and long-term peripheral nerve regeneration using a poly-lactic-co-glycolic-acid scaffold containing nerve growth factor and glial cell line-derived neurotrophic factor releasing microspheres, Journal of Biomedical Materials Research Part A 100A(8): 2139-2146.
- Buitenhuis, S.; Wijlen-Hempel, R.S. van; Pondaag, W. & Malessy, M.J.A. (2012), Obstetric brachial plexus lesions and central developmental disability.
- Post, R.; Boer, K.S. de & Malessy, M.J.A. (2012), Outcome following Nerve Repair of High Isolated Clean Sharp Injuries of the Ulnar Nerve, PLoS ONE 7(10): -.
- Steens, S.C.A.; Pondaag, W.; Malessy, M.J.A. & Verbist, B.M. (2011), Obstetric Brachial Plexus Lesions: CT Myelography, Radiology 259(2): 508-515.
- Boer, R. de; Knight, A.M.; Borntraeger, A.; Hebert-Blouin, M.N.; Spinner, R.J.; Malessy, M.J.A.; Yaszemski, M.J. & Windebank, A.J. (2011), RAT SCIATIC NERVE REPAIR WITH A POLY-LACTIC-co-GLYCOLIC ACID SCAFFOLD AND NERVE GROWTH FACTOR RELEASING MICROSPHERES, Microsurgery 31(4): 293-302.
- Mason, M.R.J.; Tannemaat, M.R.; Malessy, M.J.A. & Verhaagen, J. (2011), Gene Therapy for the Peripheral Nervous System: A Strategy to Repair the Injured Nerve?, Current Gene Therapy 11(2): 75-89.
- Hoyng, S.A.; Tannemaat, M.R.; Winter, F. de; Verhaagen, J. & Malessy, M.J.A. (2011), Nerve surgery and gene therapy: a neurobiological and clinical perspective, Journal of Hand Surgery (European Volume) 36E(9): 735-746.
- Malessy, M.J.A.; Pondaag, W.; Yang, L.J.S.; Hofstede-Buitenhuis, S.M.; Cessie, S. le & Dijk, J.G. van (2011), Severe Obstetric Brachial Plexus Palsies Can Be Identified at One Month of Age, PLoS ONE 6(10): -.
- Pondaag, W.; Allen, R.H. & Malessy, M.J.A. (2011), Correlating birthweight with neurological severity of obstetric brachial plexus lesions, BJOG: An International Journal of Obstetrics and Gynaecology 118(9): 1098-1103.
- Pondaag, W.; Dijk, J.G. van & Malessy, M.J.A. (2010), Obstetric brachial plexus palsy, Developmental Medicine and Child Neurology 52(6): 502-502.
- Pondaag, W.; Dijk, J.G. van & Malessy, M.J.A. (2010), Obstetric brachial plexus lesions RESPONSE, Journal of Neurosurgery 112(3): 695-696.
- Boer, R. de; Knight, A.M.; Spinner, R.J.; Malessy, M.J.A.; Yaszemski, M.J. & Windebank, A.J. (2010), In vitro and in vivo release of nerve growth factor from biodegradable poly-lactic-co-glycolic-acid microspheres, Journal of Biomedical Materials Research Part A 95A(4): 1067-1073.
- Siqueira, M.G.; Foroni, L.H.L.; Martins, R.S.; Chadi, G. & Malessy, M.J.A. (2010), Fascicular Topography of the Suprascapular Nerve in the C5 Root and Upper Trunk of the Brachial Plexus: A Microanatomic Study From a Nerve Surgeon's Perspective, Neurosurgery 67.
- Tannemaat MR, Boer GJ, Eggers R, Malessy MJ & Verhaagen J (2009), From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve., Progress in Brain Research 175: 173-86.
- Malessy MJA & Pondaag W (2009), Obstetric Brachial Plexus Injuries, Neurosurgery Clinics of North America 20(1): 1+.
- Godefroy WP, van der Mey AGL, de Bruine FT, Hoekstra ER & Malessy MJA (2009), Surgery for Large Vestibular Schwannoma: Residual Tumor and Outcome, Otology and Neurotology 30(5): 629-634.
- de Ruiter GCW, Spinner RJ, Yaszemski MJ, Windebank AJ & Malessy MJA (2009), Nerve Tubes for Peripheral Nerve Repair.
- Malessy MJA, Pondaag W & van Dijk JG (2009), ELECTROMYOGRAPHY, NERVE ACTION POTENTIAL, AND COMPOUND MOTOR ACTION POTENTIALS IN OBSTETRIC BRACHIAL PLEXUS LESIONS: VALIDATION IN THE ABSENCE OF A "GOLD STANDARD", Neurosurgery 65(4): A153A159.
- Ruiter GCW, Malessy MJA, Yaszemski MJ, Windebank AJ & Spinner RJ (2009), Designing ideal conduits for peripheral nerve repair, Neurosurgical focus 26(2).
- Hofstede-Buitenhuis SM, van Wijlen-Hempel MS, Malessy M & Pondaag W (2009), Obstetrisch Plexus Brachialis Letsel .
- Hofstede- Buitenhuis SM, Malessy MJA, Pondaag W, van Wijlen- Hempel MS, de Boer K, Nelissen RGHH & Nagels J (2009), Het Steindler-effect bij het obstetrisch plexus brachialis letsel: Elleboogflexie ondanks paralytische m.biceps.
- Pondaag W, van der Veken LPAJ, van Someren PJ, van Dijk JG & Malessy MJA (2008), Intraoperative nerve action and compound motor action potential recordings in patients with obstetric brachial plexus lesions, Journal of Neurosurgery 109(5).
- Tannemaat MR, Eggers R, Hendriks WT, de Ruiter GCW, van Heerikhuize JJ, Pool CW, Malessy MJA, Boer GJ & Verhaagen J (2008), Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve, European Journal of Neuroscience 28(8).
- Tannemaat MR, Verhaagen J & Malessy M (2008), The application of viral vectors to enhance regeneration after peripheral nerve repair, Neurological Research 30(10): 1039-1046.
- de Ruiter GCW, Malessy MJA, Alaid AO, Spinner RJ, Engelstad JK, Sorenson EJ, Kaufman KR, Dyck PJ & Windebank AJ (2008), Misdirection of regenerating motor axons after nerve injury and repair in the rat sciatic nerve model, Experimental Neurology 211(2).
- Anastakis DJ, Malessy MJA, Chen R, Davis KD & Mikulis D (2008), Cortical Plasticity Following Nerve Transfer in the Upper Extremity, Hand Clinics 24(4).
- de Ruiter GC, Spinner RJ, Malessy MJA, Moore MJ, Sorenson EJ, Currier BL, Yaszemski MJ & Windebank AJ (2008), Accuracy of motor axon regeneration across autograft, single-lumen, and multichannel poly(lactic-co-glycolic acid) nerve tubes, Neurosurgery 63(1).
- de Ruiter GC, Onyeneho IA, Liang ET, Moore MJ, Knight AM, Malessy MJA, Spinner RJ, Lu L, Currier BL, Yaszemski MJ & Windebank AJ (2008), Methods for in vitro characterization of multichannel nerve tubes, Journal of Biomedical Materials Research Part A 84A(3).
- Pondaag W, van der Veken LP, van Someren PJ, van Dijk JG & Malessy MJ (2008), Intraoperative nerve action and compound motor action potential recordings in patients with obstetric brachial plexus lesions., Journal of Neurosurgery 109(5): 946-54.
- van Dijk JG, Pondaag W & Malessy MJA (2007), Botuhnum toxin and the pathophysiology of obstetric brachial plexus lesions, Developmental Medicine and Child Neurology 49(4).
- de Ruiter GC, Spinner RJ, Alaid AO, Koch AJ, Wang H, Malessy MJA, Currier BL, Yaszemski MJ, Kaufman KR & Windebank AJ (2007), Two-dimensional digital video ankle motion analysis for assessment of function in the rat sciatic nerve model, Journal of the Peripheral Nervous System 12(3).
- de Ruiter GCW, Malessy MJA, Spinner RJ, Alaid A, Engelstad JK, Sorenson EJ, Kaufman KR, Dyck PJ & Windebank AJ (2007), Misdirection of regenerating motor axons after nerve injury and repair in the rat sciatic nerve model, Journal of the Peripheral Nervous System 12.
- Hastan D, Godefroy WP, Malessy MJA & van der Mey AGL (2007), Establishing a method to predict the outcome of vestibular schwannoma surgery based on one's own results, Clinical Otolaryngology 32(5).
- Tannemaat MR, Boer GJ, Verhaagen J & Malessy MJA (2007), Genetic modification of human sural nerve segments by a lentiviral vector encoding nerve growth factor, Neurosurgery 61(6).
- Tannemaat MR, Korecka J, Ehlert EME, Mason MRJ, van Duinen SG, Boer GJ, Malessy MJA & Verhaagen J (2007), Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro, Journal of Neuroscience 27(52).
- Vleggeert-Lankamp CLAM, de Ruiter GCW, Wolfs JFC, Pego AP, van den Berg RJ, Feirabend HKP, Malessy MJA & Lakke EAJF (2007), Pores in synthetic nerve conduits are beneficial to regeneration, Journal of Biomedical Materials Research Part A 80A(4).
- Godefroy WP, Malessy MJA, Tromp AAM & van der Mey AGL (2007), Intratemporal facial nerve transfer with direct coaptation to the hypoglossal nerve, Otology and Neurotology 28(4).
- de Boer R, Knight AM, Malessy MJA, Spinner RJ, Yaszemski MJ & Windebank AJ (2007), Effect of polymer composition on release kinetics of nerve growth factor from polylactic-co-glycolic acid microspheres, Journal of the Peripheral Nervous System 12.
- Pondaag W, de Boer R, van Wijlen-Hempel MS, Hofstede-Buitenhuis SM & Malessy MJA (2005), External rotation as a result of suprascapular nerve neurotization in obstetric brachial plexus lesions.
- Pondaag W, Malessy MJA, van Dijk JG & Thomeer RTWM (2004), Natural history of obstetric brachial plexus palsy: a systematic review, Developmental Medicine and Child Neurology 46(2).
- Malessy MJA, de Ruiter GCW, de Boer KS & Thomeer RTWM (2004), Evaluation of suprascapular nerve neurotization after nerve graft or transfer in the treatment of brachial plexus traction lesions, Journal of Neurosurgery 101(3).
- Malessy MJA, Bakker D, Dekker J, Van Dijk JG & Thomeer RTWM (2003), Functional magnetic resonance imaging and control over the biceps muscle after intercostal-musculocutaneous nerve transfer, Journal of Neurosurgery 98(2).
- Thomeer RTWM, Malessy MJA & Marani E (2002), Nerve root repair, Journal of Neurosurgery 96(1).
- van Dijk JG, Pondaag W & Malessy MJA (2001), Obstetric lesions of the brachial plexus, Muscle and Nerve 24(11).
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