Jeroen Eikenboom
Professor Internal Medicine
- Name
- Prof.dr. H.C.J. Eikenboom
- Telephone
- +31 71 526 4906
- h.c.j.eikenboom@lumc.nl
- ORCID iD
- 0000-0002-3268-5759
Jeroen C.J. Eikenboom is professor of Internal Medicine, especially Hemostasis and Thrombosis. He is board certified internist vascular medicine and hematologist. He is working at the department of Internal Medicine and is head of the division of Thrombosis and Hemostasis.
More information about Jeroen Eikenboom
Jeroen C.J. Eikenboom is professor of Internal Medicine, especially Hemostasis and Thrombosis. He is board certified internist vascular medicine and hematologist. He is working at the department of Internal Medicine and is head of the division of Thrombosis and Hemostasis.
Bleeding disorders
Blood should remain fluid when blood vessels are intact to secure the circulation. However, upon vascular damage blood should quickly clot to prevent blood loss. This delicate balance is called the thrombo-haemorrhagic balance. Disorders of this balance may lead to excessive bleeding or increased risk of thrombosis. Through clinical and fundamental research of haemostatic disorders Eikenboom tries to gain insight in the pathophysiology of bleeding disorders. Bleeding risk is a multidisciplinary problem that involves several disciplines like internal medicine, paediatrics, gynaecology, and surgery. Collaborative efforts among these specialties is of great importance for scientific research as well as clinical care of bleeding disorders.
The research of Eikenboom focuses mainly on the molecular genetics of von Willebrand disease, the genotype-phenotype associations in von Willebrand disease, and the biochemical and cell biological aspects of synthesis, storage, secretion, and clearance of von Willebrand factor. In addition to these pathophysiological studies he is also working on the development of new, innovative treatment strategies (e.g. RNA interference) for von Willebrand disease and thrombosis.
Academic career
Jeroen Eikenboom received his MD degree in 1988 at the Erasmus University Rotterdam. He obtained his PhD at the Leiden University and defended his thesis, entitled "The inheritance of von Willebrand disease", on November 23, 1994. He was trained in internal medicine at the Leiden University Medical Center and registered as internist in 2001. Since then he sub-specialized in hematology and vascular medicine. In 2008-2009 he was visiting scientist at the Life Sciences Institute of the University of Michigan Medical School in Ann Arbor, Michigan, USA. He was appointed full professor of Internal Medicine, especially Hemostasis and Thrombosis in 2011. March 9, 2012 he held his inaugural speech, entitled “The hemostasis integral”.
Jeroen Eikenboom has been (co)chairman of the Scientific Subcommittee on von Willebrand factor of the Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis (ISTH) from 1999-2013. He is associate editor of journal HemaSphere. He is chair of the board of the Dutch Society of Hemophilia Treaters (NVHB). Furthermore, he is chair of the scientific advisory board of the Landsteiner Foundation for Blood Transfusion Research (LSBR).
Professor Internal Medicine
- Faculteit Geneeskunde
- Divisie 2
- Interne Geneeskunde
- A.I.G. algemeen
- Pagliari, M.T.; Budde, U.; Baronciani, L.; Eshghi, P.; Ahmadinejad, M.; Badiee, Z.; Baghaipour, M.R.; Hidalgo, O.B.; Biguzzi, E.; Bodó, I.; Castaman, G.; Goudemand, J.; Karimi, M.; Keikhaei, B.; Lassila, R.; Leebeek, F.W.G.; Fernandez, M.F.L.; Marino, R.; Oldenburg, J.; Peake, I.; Santoro, C.; Schneppenheim, R.; Tiede, A.; Toogeh, G.; Tosetto, A.; Trossaert, M.; Yadegari, H.; Zetterberg, E.M.K.; Mannucci, P.M.; Federici, A.B.; Eikenboom, J. & Peyvandi, F. (2023), Von Willebrand factor neutralizing and non-neutralizing alloantibodies in 213 subjects with type 3 von Willebrand disease enrolled in 3WINTERS-IPS, Journal of Thrombosis and Haemostasis 21(4): 787-799.
- Strijbis, V.J.F.; Romano, L.G.R.; Cheung, K.L.; Eikenboom, J.; Liu, Y.P.; McCreary, A.C.; Leebeek, F.W.G. & Bos, M.H.A. (2023), A factor IX variant that functions independently of factor VIII mitigates the hemophilia, Journal of Thrombosis and Haemostasis 21(6): 1466-1477.
- Jongejan, Y.K.; Echeverri, E.S.; Dirven, R.J.; Paunovska, K.; Linthorst, N.A.; Jong, A. de; Wellershoff, J.C.; Gouw, K.D. van der; Vlijmen, B.J.M. van; Dahlman, J.E. & Eikenboom, J.C.J. (2023), Small interfering RNA-mediated allele-selective silencing of von Willebrand factor in vitro and in vivo, Blood Advances 7(20): 6108-6119.
- Zwagemaker, A.F.; Kloosterman, F.R.; Gouw, S.C.; Boyce, S.; Brons, P.; Cnossen, M.H.; Collins, P.W.; Eikenboom, J.; Hay, C.; Hengeveld, R.C.C.; Jackson, S.; Klopper-Tol, C.A.M.; Kruip, M.J.H.A.; Laros-van Gorkom, B.; Male, C.; Nieuwenhuizen, L.; Shapiro, S.; Fijnvandraat, K.; Copens, M. & DYNAMO Study Grp (2023), Little discrepancy between one-stage and chromogenic factor VIII (FVIII)/IX assays in a large international cohort of persons with nonsevere hemophilia A and B, Journal of Thrombosis and Haemostasis 21(4): 850-861.
- Brands, M.R.; Janssen, E.A.M.; Cnossen, M.H.; Smit, C.; Vulpen, L.F.D. van; Valk, P. van der; Eikenboom, J.; Heubel-Moenen, F.C.J.I.; Hooimeijer, L.; Ypma, P.; Nieuwenhuizen, L.; Coppens, M.; Schols, S.E.M.; Laros-Van Gorkom, B.A.P.; Leebeek, F.W.G.; Driessens, M.H.E.; Rosendaal, F.R.; Bom, J. van der; Fijnvandraat, K. & Gouw, S.C. (2023), Transition readiness among adolescents and young adults with haemophilia in the Netherlands, Haemophilia 29(5): 1191-1201.
- Laan, S.N.J.; Dirven, R.J.; Bürgisser, P.E.; Eikenboom, J.; Bierings, R. & SYMPHONY consortium (2023), Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfiler, PLoS ONE 18(6).
- Monahan, R.C.; Voorde, L.J.J. van de; Fronczek, R.; Bresser, J. de; Eikenboom, J.; Kloppenburg, M.; Middelkoop, H.A.M.; Terwindt, G.M.; Wee, N.J.A. van der; Huizinga, T.W.J. & Steup-Beekman, G.M. (2023), Clinical outcome in patients with suspected inflammatory neuropsychiatric lupus treated with immunosuppression, Lupus Science & Medicine 10(1).
- Kempers, E.K.; Kwawegen, C.B. van; Meris, J. de; Spaander, M.C.W.; Schols, S.E.M.; Ypma, P.F.; Heubel-Moenen, F.C.J.I.; Vulpen, L.F.D. van; Coppens, M.; Bom, J.G. van der; Fijnvandraat, K.; Meijer, K.; Eikenboom, J.; Gouw, S.C.; Leebeek, F.W.G. & Kruip, M.J.H.A. (2023), Colorectal cancer screening in patients with inherited bleeding disorders, Journal of Thrombosis and Haemostasis 21(5): 1177-1188.
- Swinkels, M.; Atiq, F.; Burgisser, P.E.; Moort, I. van; Meijer, K.; Eikenboom, J.; Fijnvandraat, K.; Galen, K.P.M. van; Meris, J. de; Schols, S.E.M.; Bom, J.G. van der; Cnossen, M.H.; Voorberg, J.; Leebeek, F.W.G.; Bierings, R.; Jansen, A.J.G. & WiN Study Grp (2022), Platelet degranulation and bleeding phenotype in a large cohort of Von Willebrand disease patients, British Journal of Haematology 197(4): 497-501.
- Balen, E.C. van; Hassan, S.; Smit, C.; Driessens, M.H.E.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.C.; Hooimeijer, H.L.; Leebeek, F.W.G.; Mauser-Bunschoten, E.P.; Vulpen, L.F.D. van; Schols, S.E.M.; Rosendaal, F.R.; Bom, J.G. van der & Gouw, S.C. (2022), Socioeconomic participation of persons with hemophilia, Research and Practice in Thrombosis and Haemostasis 6(6).
- Cnossen, M.H.; Moort, I. van; Reitsma, S.H.; Maat, M.P.M. de; Schutgens, R.E.G.; Urbanus, R.T.; Lingsma, H.F.; Mathot, R.A.A.; Gouw, S.C.; Meijer, K.; Bredenoord, A.L.; Graaf, R. van der; Fijnvandraat, K.; Meijer, A.B.; Akker, E. van den; Bierings, R.; Eikenboom, J.C.J.; Biggelaar, M. van den; Haas, M. de; Voorberg, J.; Leebeek, F.W.G. & SYMPHONY Consortium (2022), SYMPHONY consortium, Journal of Thrombosis and Haemostasis 20(9): 2001-2011.
- Zwagemaker, A.F.; Kloosterman, F.R.; Coppens, M.; Gouw, S.C.; Boyce, S.; Bagot, C.N.; Beckers, E.A.M.; Brons, P.; Castaman, G.; Eikenboom, J.; Jackson, S.; Kruip, M.J.H.A.; Leebeek, F.W.G.; Meijer, K.; Nieuwenhuizen, L.; Pabinger, I. & Fijnvandraat, K. (2022), Desmopressin for bleeding in non-severe hemophilia A, Research and Practice in Thrombosis and Haemostasis 6(6).
- Kalot, M.A.; Husainat, N.; Alayli, A. el; Abughanimeh, O.; Diab, O.; Tayiem, S.; Madoukh, B.; Dimassi, A.B.; Qureini, A.; Ameer, B.; Eikenboom, J.C.J.; Giraud, N.; McLintock, C.; McRae, S.; Montgomery, R.R.; O'Donnell, J.S.; Scappe, N.; Sidonio, R.F.; Brignardello-Petersen, R.; Flood, V.H.; Connell, N.T.; James, P.D. & Mustafa, R.A. (2022), von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis, Blood Advances 6(1): 62-71.
- Pagliari, M.T.; Rosendaal, F.R.; Ahmadinejad, M.; Badiee, Z.; Baghaipour, M.R.; Baronciani, L.; Hidalgo, O.B.; Bodo, I.; Budde, U.; Castaman, G.; Eshghi, P.; Goudemand, J.; Karimi, M.; Keikhaei, B.; Lassila, R.; Leebeek, F.W.G.; Fernandez, M.F.L.; Mannucci, P.M.; Marino, R.; Oldenburg, J.; Peake, I.; Santoro, C.; Schneppenheim, R.; Tiede, A.; Toogeh, G.; Tosetto, A.; Trossaert, M.; Yadegari, H.; Zetterberg, E.M.K.; Peyvandi, F.; Federici, A.B. & Eikenboom, J. (2022), Von Willebrand factor propeptide and pathophysiological mechanisms in European and Iranian patients with type 3 von Willebrand disease enrolled in the 3WINTERS-IPS study, Journal of Thrombosis and Haemostasis 20(5): 1106-1114.
- Tahitu, M.; Ramler, P.I.; Gillissen, A.; Caram-Deelder, C.; Henriquez, D.D.C.A.; Maat, M.P.M. de; Duvekot, J.J.; Eikenboom, J.; Bloemenkamp, K.W.M.; Akker, T. van den & Bom, J.G. van der (2022), Clinical value of early assessment of hyperfibrinolysis by rotational thromboelastometry during postpartum hemorrhage for the prediction of severity of bleeding, Acta Obstetricia et Gynecologica Scandinavica 101(1): 145-152.
- Heesterbeek, M.R.; Luijten, M.A.J.; Gouw, S.C.; Limperg, P.F.; Fijnvandraat, K.; Coppens, M.; Kruip, M.J.H.A.; Eikenboom, J.; Grootenhuis, M.A.; Flens, G.; Terwee, C.B.; Peters, M. & Haverman, L. (2022), Measuring anxiety and depression in young adult men with haemophilia using PROMIS.
- Grewal, N.; Yousef, D.; Palmen, M.; Klautz, R.; Eikenboom, J. & Wink, J. (2022), Accuracy of point-of-care coagulation testing during cardiopulmonary bypass in a patient post COVID-19 infection, Journal of Cardiothoracic Surgery 17(1).
- Atiq, F.; Boender, J.; Heerde, W.L. van; Garcia, J.M.T.; Schoormans, S.C.; Krouwel, S.; Cnossen, M.H.; Laros-van Gorkom, B.A.P.; Meris, J. de; Fijnvandraat, K.; Bom, J.G. van der; Meijer, K.; Galen, K.P.M. van; Eikenboom, J.; Leebeek, F.W.G. & WIN Study Grp (2022), Importance of genotyping in von Willebrand disease to elucidate pathogenic mechanisms and variability in phenotype, HemaSphere 6(6).
- Arisz, R.A.; Vries, J.J. de; Schols, S.E.M.; Eikenboom, J.C.J.; Maat, M.P.M. de & Consortium (2022), Interaction of von Willebrand factor with blood cells in flow models: a systematic review, Blood Advances 6(13): 3979-3990.
- Kalot, M.A.; Husainat, N.; Abughanimeh, O.; Diab, O.; Alayli, A. el; Tayiem, S.; Madoukh, B.; Dimassi, A.; Qureini, A.; Ameer, B.; Eikenboom, J.; Giraud, N.; Haberichter, S.; Jacobs-Pratt, V.; Konkle, B.A.; McRae, S.; Montgomery, R.; O'Donnell, J.S.; Brignardello-Petersen, R.; Flood, V.; Connell, N.T.; James, P. & Mustafa, R.A. (2022), Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis, Blood Advances 6(12): 3735-3745.
- Kempers, E.K.; Kwawegen, C.B. van; Meris, J. de; Schols, S.E.M.; Galen, K.P.M. van; Meijer, K.; Cnossen, M.H.; Bom, J.G. van der; Fijnvandraat, K.; Eikenboom, J.; Atiq, F.; Leebeek, F.W.G. & WiN Study Grp (2021), Social participation is reduced in type 3 Von Willebrand disease patients and in patients with a severe bleeding phenotype, Haemophilia 28(2).
- Kruijt, M.; Pol, L.M. van der; Eikenboom, J.; Verburg, H.J.; Cobbaert, C.M. & Ruhaak, L.R. (2021), Unraveling a borderline antithrombin deficiency case with quantitative mass spectrometry, Journal of Thrombosis and Haemostasis 20(1).
- Hassan, S.; Monahan, R.C.; Mauser-Bunschoten, E.P.; Vulpen, L.F.D. van; Eikenboom, J.; Beckers, E.A.M.; Hooimeijer, L.; Ypma, P.F.; Nieuwenhuizen, L.; Coppens, M.; Schols, S.E.M.; Leebeek, F.W.G.; Smit, C.; Driessens, M.H.; Cessie, S. le; Balen, E.C. van; Rosendaal, F.R.; Bom, J.G. van der & Gouw, S.C. (2021), Mortality, life expectancy, and causes of death of persons with hemophilia in the Netherlands 2001-2018, Journal of Thrombosis and Haemostasis 19(3): 645-653.
- Boender, J.; Atiq, F.; Cnossen, M.H.; Bom, J.G. van der; Fijnvandraat, K.; Meris, J. de; Maat, M.P.M. de; Galen, K.P.M. van; Laros-van Gorkom, B.A.P.; Meijer, K.; Eikenboom, J. & Leebeek, F.W.G. (2021), Von Willebrand factor multimer densitometric analysis, HemaSphere 5(3).
- Connell, N.T.; James, P.D.; Brignardello-Petersen, R.; Abdul-Kadir, R.; Ameer, B.; Arapshian, A.; Couper, S.; Paola, J. di; Eikenboom, J.; Giraud, N.; Grow, J.M.; Haberichter, S.; Jacobs-Pratt, V.; Konkle, B.A.; Kouides, P.; Laffan, M.; Lavin, M.; Leebeek, F.W.G.; McLintock, C.; McRae, S.; Montgomery, R.; O'Brien, S.H.; O'Donnell, J.S.; Ozelo, M.C.; Scappe, N.; Sidonio, R.; Tosetto, A.; Weyand, A.C.; Kalot, M.A.; Husainat, N.; Mustafa, R.A. & Flood, V.H. (2021), von Willebrand disease: proposing definitions for future research.
- Balen, E.C. van; Haverman, L.; Hassan, S.; Taal, E.M.; Smit, C.; Driessens, M.H.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Hooimeijer, H.L.; Leebeek, F.W.G.; Vulpen, L.F.D. van; Schols, S.E.M.; Terwee, C.B.; Rosendaal, F.R.; Bom, J.G. van der & Gouw, S.C. (2021), Validation of PROMIS Profile-29 in adults with hemophilia in the Netherlands, Journal of Thrombosis and Haemostasis 19(11).
- Versloot, O.; Balen, E.C. van; Hassan, S.; Schols, S.E.M.; Leebeek, F.W.G.; Eikenboom, J.; Coppens, M.; Vulpen, L.F.D. van; Smit, C.; Driessens, M.H.E.; Net, J. van der; Gouw, S.C.; Fischer, K. & Haemophilia Netherlands 6 Steering (2021), Similar sports participation as the general population in Dutch persons with haemophilia, Haemophilia 27(5): 876-885.
- Biguzzi, E.; Castelli, F.; Lijfering, W.M.; Cannegieter, S.C.; Eikenboom, J.; Rosendaal, F.R. & Vlieg, A.V. (2021), Rise of levels of von Willebrand factor and factor VIII with age: Role of genetic and acquired risk factors, Thrombosis Research: Vascular Obstruction, Hemorrhage and Hemostasis 197: 172-178.
- Bukkems, L.H.; Heijdra, J.M.; Jager, N.C.B. de; Hazendonk, H.C.A.M.; Fijnvandraat, K.; Meijer, K.; Eikenboom, J.C.J.; Laros-van Gorkom, B.A.P.; Leebeek, F.W.G.; Cnossen, M.H.; Mathot, R.A.A. & OPTI-CLOT Study Grp (2021), Population pharmacokinetics of the von Willebrand factor-factor VIII interaction in patients with von Willebrand disease, Blood Advances 5(5): 1513-1522.
- Punt, M.C.; Waning, M.L.; Mauser-Bunschoten, E.P.; Kruip, M.J.H.A.; Eikenboom, J.; Nieuwenhuizen, L.; Makelburg, A.B.U.; Driessens, M.H.E.; Duvekot, J.J.; Peters, M.; Middeldorp, J.M.; Bloemenkamp, K.W.M.; Schutgens, R.E.G.; Lely, A.T. & Galen, K.P.M. van (2021), Maternal and neonatal bleeding complications in relation to peripartum management in hemophilia carriers: a systematic review, Blood Reviews 49.
- Atiq, F.; Saes, J.L.; Punt, M.C.; Galen, K.P.M. van; Schutgens, R.E.G.; Meijer, K.; Cnossen, M.H.; Laros-Van Gorkom, B.A.P.; Peters, M.; Nieuwenhuizen, L.; Kruip, M.J.H.A.; Meris, J. de; Bom, J.G. van der; Meer, F.J.M. van der; Fijnvandraat, K.; Kruis, I.C.; Heerde, W.L. van; Eikenboom, H.C.J.; Leebeek, F.W.G.; Schols, S.E.M.; WiN Study Grp; RBiN Study Grp & TiN Study Grp (2021), Major differences in clinical presentation, diagnosis and management of men and women with autosomal inherited bleeding disorders, EClinicalMedicine 32.
- Hassan, S.; Balen, E.C. van; Smit, C.; Mauser-Bunschoten, E.P.; Vulpen, L.F.D. van; Eikenboom, J.; Beckers, E.A.M.; Hooimeijer, L.; Ypma, P.F.; Nieuwenhuizen, L.; Coppens, M.; Schols, S.E.M.; Leebeek, F.W.G.; Driessens, M.H.; Rosendaal, F.R.; Bom, J.G. van der & Gouw, S.C. (2021), Health and treatment outcomes of patients with hemophilia in the Netherlands, 1972-2019, Journal of Thrombosis and Haemostasis 19(10): 2394-2406.
- Baronciani, L.; Peake, I.; Schneppenheim, R.; Goodeve, A.; Ahmadinejad, M.; Badiee, Z.; Baghaipour, M.R.; Benitez, O.; Bodo, I.; Budde, U.; Cairo, A.; Castaman, G.; Eshghi, P.; Goudemand, J.; Hassenpflug, W.; Hoorfar, H.; Karimi, M.; Keikhaei, B.; Lassila, R.; Leebeek, F.W.G.; Fernandez, M.F.L.; Mannucci, P.M.; Marino, R.; Niksic, N.; Oyen, F.; Santoro, C.; Tiede, A.; Toogeh, G.; Tosetto, A.; Trossaert, M.; Zetterberg, E.M.K.; Eikenboom, J.; Federici, A.B. & Peyvandi, F. (2021), Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS, Blood Advances 5(15): 2987-3001.
- Monahan, R.C.; Beaart-van de Voorde, L.J.J.; Eikenboom, J.; Fronczek, R.; Kloppenburg, M.; Middelkoop, H.A.M.; Terwindt, G.M.; Wee, N.J.A. van der; Huizinga, T.W.J. & Steup-Beekman, G.M. (2021), Fatigue in patients with systemic lupus erythematosus and neuropsychiatric symptoms is associated with anxiety and depression rather than inflammatory disease activity, Lupus 30(7).
- Wind, M.; Hendriks, M.; Brussel, B.T.J. van; Eikenboom, J.; Allaart, C.F.; Lamb, H.J.; Siebelink, H.M.J.; Ninaber, M.K.; Geloven, N. van; Lith, J.M.M. van; Huizinga, T.W.J.; Rabelink, T.J.; Sueters, M. & Teng, Y.K.O. (2021), Effectiveness of a multidisciplinary clinical pathway for women with systemic lupus erythematosus and/or antiphospholipid syndrome, Lupus Science & Medicine 8(1).
- Wal, L.I. van der; Kroft, L.J.M.; Dam, L.F. van; Cobbaert, C.M.; Eikenboom, J.; Huisman, M.V.; Helmerhorst, H.J.F.; Klok, F.A.; Jonge, E. de & Dutch Covid Thrombosis Coalition (2021), Early effects of unfractionated heparin on clinical and radiological signs and D-dimer levels in patients with COVID-19 associated pulmonary embolism: an observational cohort study.
- Ramler, P.I.; Gillissen, A.; Henriquez, D.D.C.A.; Caram-Deelder, C.; Markovski, A.A.; Maat, M.P.M. de; Duvekot, J.J.; Eikenboom, J.C.J.; Bloemenkamp, K.W.M.; Lith, J.M.M. van; Akker, T. van den & Bom, J.G. van der (2021), Clinical value of early viscoelastometric point-of-care testing during postpartum hemorrhage for the prediction of severity of bleeding, Acta Obstetricia et Gynecologica Scandinavica 100(9): 1656-1664.
- Jongejan, Y.K.; Eikenboom, J.C.J.; Gijbels, M.J.J.; Berbee, J.F.P. & Vlijmen, B.J.M. van (2021), Atherothrombosis model by silencing of protein C in APOE*3-Leiden.CETP transgenic mice, Journal of Thrombosis and Thrombolysis 52.
- James, P.D.; Connell, N.T.; Ameer, B.; Paola, J. di; Eikenboom, J.; Giraud, N.; Haberichter, S.; Jacobs-Pratt, V.; Konkle, B.; McLintock, C.; McRae, S.; Montgomery, R.R.; O'Donnell, J.S.; Scappe, N.; Sidonio, R.; Flood, V.H.; Husainat, N.; Kalot, M.A. & Mustafa, R.A. (2021), ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease, Blood Advances 5(1): 280-300.
- Hoefnagels, J.W.; Schrijvers, L.H.; Leebeek, F.W.G.; Eikenboom, J.; Schols, S.E.M.; Smit, C.; Schutgens, R.E.G.; Gouw, S.C.; Fischer, K. & Haemophilia Netherlands 6 Steering (2021), Adherence to prophylaxis and its association with activation of self-management and treatment satisfaction, Haemophilia 27(4): 581-590.
- Kalot, M.A.; Husainat, N.; Tayiem, S.; Alayli, A. el; Dimassi, A.B.; Diab, O.; Abughanimeh, O.; Madoukh, B.; Qureini, A.; Ameer, B.; Paola, J. di; Eikenboom, J.C.J.; Jacobs-Pratt, V.; McLintock, C.; Montgomery, R.; O'Donnell, J.S.; Sidonio, R.; Brignardello-Petersen, R.; Flood, V.; Connell, N.T.; James, P.D. & Mustafa, R.A. (2021), Bleeding assessment tools in the diagnosis of VWD in adults and children: a systematic review and meta-analysis of test accuracy, Blood Advances 5(23): 5023-5031.
- Isfordink, C.J.; Gouw, S.C.; Balen, E.C. van; Hassan, S.; Beckers, E.A.M.; Bom, J.G. van der; Coppens, M.; Eikenboom, J.; Fischer, K.; Hooimeijer, L.; Leebeek, F.W.G.; Rosendaal, F.R.; Schols, S.E.M.; Smit, C.; Vulpen, L.F.D. van & Mauser-Bunschoten, E.P. (2021), Hepatitis C virus in hemophilia, Research and Practice in Thrombosis and Haemostasis 5(8).
- Moort, I. van; Bukkems, L.H.; Heijdra, J.M.; Schutgens, R.E.G.; Laros-van Gorkom, B.A.P.; Nieuwenhuizen, L.; Meer, F.J.M. van der; Fijnvandraat, K.; Ypma, P.; Maat, M.P.M. de; Leebeek, F.G.; Meijer, K.; Eikenboom, J.; Mathot, R.A.A.; Cnossen, M.H. & OPTI-CLOT Study Grp (2020), von Willebrand factor and factor VIII clearance in perioperative hemophilia a patients, Thrombosis and Haemostasis 120(7): 1056-1065.
- Exter, P.L. den; Beeres, S.L.M.A.; Eikenboom, J.; Klok, F.A. & Huisman, M.V. (2020), Anticoagulant treatment and bleeding complications in patients with left ventricular assist devices, Expert Review of Cardiovascular Therapy 18(6): 363-372.
- Schep, S.J.; Dijk, W.E.M. van; Beckers, E.A.M.; Meijer, K.; Coppens, M.; Eikenboom, J.; Leebeek, F.W.G.; Vulpen, L.F.D. van; Fischer, K.F.; Schutgens, R.E.G. & Dutch Soc Haemophilia Treaters (2020), Treatment of acquired hemophilia A (AHA), a balancing act, American Journal of Hematology 96(1).
- Monahan, R.C.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.A.M.; Beaart-van de Voorde, L.J.J.; Terwindt, G.M.; Wee, N.J.A. van der; Rosendaal, F.R.; Huizinga, T.W.J.; Kloppenburg, M. & Steup-Beekman, G.M. (2020), Mortality in patients with systemic lupus erythematosus and neuropsychiatric involvement: A retrospective analysis from a tertiary referral center in the Netherlands, Lupus 29(14): 1892-1901.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.; Terwindt, G.; Wee, N. van der; Rosendaal, F.; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, M. (2020), Mortality in patients with systemic lupus erythematosus and neuropsychiatric involvement: A retrospective analysis from a tertiary referral center in the Netherlands, Lupus 29(14): 1892-1901.
- Dam, L.F. van; Kroft, L.J.M.; Wal, L.I. van der; Cannegieter, S.C.; Eikenboom, J.; Jonge, E. de; Huisman, M.V. & Klok, F.A. (2020), More on clinical and computed tomography characteristics of COVID-19 associated acute pulmonary embolism.
- Punt, M.C.; Waning, M.L.; Mauser-Bunschoten, E.P.; Kruip, M.J.H.A.; Eikenboom, J.; Nieuwenhuizen, L.; Makelburg, A.B.U.; Driessens, M.H.E.; Duvekot, J.J.; Peters, M.; Middeldorp, J.M.; Bloemenkamp, K.W.M.; Schutgens, R.E.G.; Lely, A.T. & Galen, K.P.M. van (2020), Maternal and neonatal bleeding complications in relation to peripartum management in women with Von Willebrand disease: a systematic review, Blood Reviews 39.
- Tiemeier, G.L.; Koning, R. de; Wang, G.Q.; Kostidis, S.; Rietjens, R.G.J.; Sol, W.M.P.J.; Dumas, S.J.; Giera, M.; Berg, C.W. van den; Eikenboom, J.C.J.; Berg, B.M. van den; Carmeliet, P. & Rabelink, T.J. (2020), Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies, Stem Cells Translational Medicine 9(7): 758-772.
- Dam, L.F. van; Kroft, L.J.M.; Wal, L.I. van der; Cannegieter, S.C.; Eikenboom, J.; Jonge, E. de; Huisman, M.V. & Klok, F.A. (2020), Clinical and computed tomography characteristics of COVID-19 associated acute pulmonary embolism, Thrombosis Research: Vascular Obstruction, Hemorrhage and Hemostasis 193: 86-89.
- Limperg, P.F.; Maurice-Stam, H.; Heesterbeek, M.R.; Peters, M.; Coppens, M.; Kruip, M.J.H.A.; Eikenboom, J.; Grootenhuis, M.A. & Haverman, L. (2020), Illness cognitions associated with health-related quality of life in young adult men with haemophilia, Haemophilia 26(5): 793-799.
- Asten, I. van; Blaauwgeers, M.; Granneman, L.; Heijnen, H.F.G.; Kruip, M.J.H.A.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Tamminga, R.Y.J.; Pasterkamp, G.; Huisman, A.; Galen, K.P.M. van; Korporaal, S.J.A.; Schutgens, R.E.G. & Urbanus, R.T. (2020), Flow cytometric mepacrine fluorescence can be used for the exclusion of platelet dense granule deficiency, Journal of Thrombosis and Haemostasis 18(3): 706-713.
- Blaauwgeers, M.W.; Kruip, M.J.H.A.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Galen, K.P.M. van; Tamminga, R.Y.J.; Urbanus, R.T.; Schutgens, R.E.G. & TiN Study Grp (2020), Congenital platelet disorders and health status-related quality of life, Research and Practice in Thrombosis and Haemostasis 4(1): 100-105.
- Boender, J.; Nederlof, A.; Meijer, K.; Mauser-Bunschoten, E.P.; Cnossen, M.H.; Fijnvandraat, K.; Bom, J.G. van der; Meris, J. de; Gorkom, B.A.P.L.V.; Galen, K.P.M. van; Eikenboom, J.; Maat, M.P.M. de; Leebeek, F.W.G. & WiN Study Grp (2020), ADAMTS-13 and bleeding phenotype in von Willebrand disease, Research and Practice in Thrombosis and Haemostasis 4(8): 1331-1339.
- Jong, A. de; Dirven, R.J.; Boender, J.; Atiq, F.; Anvar, S.Y.; Leebeek, F.W.G.; Vlijmen, B.J.M. van & Eikenboom, J. (2020), Ex vivo improvement of a von Willebrand disease type 2A phenotype using an allele-specific small-interfering RNA, Thrombosis and Haemostasis 120(11): 1569-1579.
- Blaauwgeers, M.W.; Kruip, M.J.H.A.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Galen, K.P.M. van; Tamminga, R.Y.J.; Urbanus, R.T. & Schutgens, R.E.G. (2020), Bleeding phenotype and diagnostic characterization of patients with congenital platelet defects, American Journal of Hematology 95(10): 1142-1147.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.J.J.; Terwindt, G.; Wee, N. van der; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, G.M. (2020), Extreme fatigue in patients with systemic Lupus erythematosus and neuropsychiatric symptoms , Annals of the Rheumatic Diseases 79: 1487-1488.
- Tosetto, A.; Badiee, Z.; Baghaipour, M.R.; Baronciani, L.; Battle, J.; Berntorp, E.; Bodo, I.; Budde, U.; Castaman, G.; Eikenboom, J.C.J.; Eshghi, P.; Ettorre, C.; Goodeve, A.; Goudemand, J.; Richard, C.; Hay, M.; Hoorfar, H.; Karimi, M.; Keikhaei, B.; Lassila, R.; Leebeek, F.W.G.; Fernandez, M.F.L.; Mannucci, P.M.; Mazzucconi, M.G.; Morfini, M.; Oldenburg, J.; Peake, I.; Lopez, R.P.; Peyvandi, F.; Schneppenheim, R.; Tiede, A.; Toogeh, G.; Trossaert, M.; Zekavat, O.; Zetterberg, E.M.K. & Federici, A.B. (2020), Bleeding symptoms in patients diagnosed as type 3 von Willebrand disease, Journal of Thrombosis and Haemostasis 18(9): 2145-2154.
- Cartwright, A.; Webster, S.J.; Jong, A. de; Dirven, R.J.; Bloomer, L.D.S.; AL-Buhairan, A.M.; Budde, U.; Hallden, C.; Habart, D.; Goudemand, J.; Peake, I.R.; Eikenboom, J.C.J.; Goodeve, A.C.; Hampshire, D.J.; European Grp von Willebrand Dis & Willebrand Dis Study Grp von (2020), Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms, Blood Advances 4(13): 2979-2990.
- Monahan, R.; Fronczek, R.; Eikenboom, J.; Middelkoop, H.; Beaart-van de Voorde, L.; Terwindt, G.; Wee, N. van der; Huizinga, T.; Kloppenburg, M. & Steup-Beekman, M. (2020), Extreme Fatigue in Patients with Systemic Lupus Erythematosus and Neuropsychiatric Symptoms, Arthritis and Rheumatology 72.
- Boer, S. de; Bowman, M.; Notley, C.; Mo, A.M.; Lima, P.; Jong, A. de; Dirven, R.; Weijers, E.; Lillicrap, D.; James, P. & Eikenboom, J. (2020), Endothelial characteristics in healthy endothelial colony forming cells, Journal of Thrombosis and Haemostasis 18(10): 2721-2731.
- Klok, F. A.; Exter, P. L. den; Huisman, M. V. & Eikenboom, J. (2020), Do’s-and-don’ts bij COVID-19-coagulopathie, Nederlands Tijdschrift voor Geneeskunde 164.
- Ypma, P.F.; Geloven, N. van; Kerkhoffs, J.L.H.; Boekhorst, P. te; Zwaginga, J.J.; Beckers, E.A.M.; Brand, A.; Meer, P.F. van der & Eikenboom, J.C.J. (2019), The association between haemorrhage and markers of endothelial insufficiency and inflammation in patients with hypoproliferative thrombocytopenia: a cohort study, British Journal of Haematology.
- Blaauwgeers, M.W.; Asten, I. van; Kruip, M.J.H.A.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Galen, K.P.M. van; Huisman, A.; Korporaal, S.J.A.; Amstel, H.K.P. van; Tamminga, R.Y.J.; Urbanus, R.T. & Schutgens, R.E.G. (2019), The limitation of genetic testing in diagnosing patients suspected for congenital platelet defects, American Journal of Hematology 95(1).
- Biesheuvel, V.; Hiddema, S.M.; Levenga, H.; Eikenboom, J. & Deure, W.M. van der (2019), Acquired haemophilia A in a patient with breast cancer and lung carcinoma: a case report and literature review, Netherlands Journal of Medicine 77(4): 153-155.
- Limper, M.; Leeuw, K. de; Lely, A.T.; Westerink, J.; Teng, Y.K.O.; Eikenboom, J.; Otter, S.; Jansen, A.J.G.; Ree, M. van der; Spierings, J.; Kruyt, N.D.; Molen, R. van der; Middeldorp, S.; Leebeek, F.W.G.; Bijl, M. & Urbanus, R.T. (2019), Diagnosing and treating antiphospholipid synarome: a consensus paper, Netherlands Journal of Medicine 77(3): 98-108.
- Limperg, P.F.; Maurice-Stam, H.; Haverman, L.; Coppens, M.; Kruip, M.J.H.A.; Eikenboom, J.; Grootenhuis, M.A. & Peters, M. (2019), Professional functioning of young adults with congenital coagulation disorders in the Netherlands, Haemophilia 25(3): E138-E145.
- Jong, A. de; Weijers, E.; Dirven, R.; Boer, S. de; Streur, J. & Eikenboom, J. (2019), Variability of von Willebrand factor-related parameters in endothelial colony forming cells, Journal of Thrombosis and Haemostasis.
- Boer, S. de & Eikenboom, J. (2019), Von Willebrand Disease: From In Vivo to In Vitro Disease Models.
- Atiq, F.; Schutte, L.M.; Looijen, A.E.M.; Boender, J.; Cnossen, M.H.; Eikenboom, J.; Maat, M.P.M. de; Kruip, M.J.H.A. & Leebeek, F.W.G. (2019), von Willebrand factor and factor VIII levels after desmopressin are associated with bleeding phenotype in type 1 VWD, Blood Advances 3(24): 4147-4154.
- Deukeren, D. van; Mauser-Bunschoten, E.P.; Schutgens, R.E.G.; Eikenboom, J.; Meijer, K.; Fijnvandraat, K.; Laros-van Gorkom, B.A.P.; Cnossen, M.; Meris, J. de; Bom, J.G. van der; Leebeek, F.W.G. & Galen, K.P.M. van (2019), The prevalence and burden of hand and wrist bleeds in von Willebrand disease.
- Hendriks, S.V.; Huisman, M.V.; Eikenboom, J.C.J.; Fogteloo, J.; Gelderblom, H.; Meer, F.J.M. van der; Stenger, W.J.E.; Verschoor, A.J.; Versteeg, H.H. & Klok, F.A. (2019), Home treatment of patients with cancer-associated venous thromboembolism - An evaluation of daily practice, Thrombosis Research 184: 122-128.
- Gillissen, A.; Akker, T. van den; Caram-Deelder, C.; Henriquez, D.D.C.A.; Bijvank, S.W.A.N.; Bloemenkamp, K.W.M.; Eikenboom, J. & Bom, J.G. van der (2019), Predictive value of a bleeding score for postpartum hemorrhage, Research and Practice in Thrombosis and Haemostasis 3(2): 277-284.
- Smadja, D.M.; Melero-Martin, J.M.; Eikenboom, J.; Bowman, M.; Sabatier, F. & Randi, A.M. (2019), Standardization of methods to quantify and culture endothelial colony-forming cells derived from peripheral blood Position paper from the International Society on Thrombosis and Haemostasis SSC, Journal of Thrombosis and Haemostasis 17(7): 1190-1194.
- Schutte, L.M.; Cnossen, M.H.; Hest, R.M. van; Driessens, M.H.E.; Fijnvandraat, K.; Polinder, S.; Beckers, E.A.M.; Coppens, M.; Eikenboom, J.; Gorkom, B.A.P.L.V.; Meijer, K.; Nieuwenhuizen, L.; Mauser-Bunschoten, E.P.; Leebeek, F.W.G.; Mathot, R.A.A. & Kruip, M.J.H.A. (2019), Desmopressin treatment combined with clotting factor VIII concentrates in patients with non-severe haemophilia A: protocol for a multicentre single-armed trial, the DAVID study, BMJ Open 9(4).
- Gillissen, A.; Akker, T. van den; Caram-Deelder, C.; Henriquez, D.D.C.A.; Bloemenkamp, K.W.M.; Eikenboom, J.; Bom, J.G. van der & Maat, M.P.M. de (2019), Comparison of thromboelastometry by ROTEM (R) Delta and ROTEM (R) Sigma in women with postpartum haemorrhage, Scandinavian Journal of Clinical and Laboratory Investigation 79(1-2): 32-38.
- Atiq, F.; Fijnvandraat, K.; Galen, K.P.M. van; Laros-Van Gorkom, B.A.P.; Meijer, K.; Meris, J. de; Coppens, M.; Mauser-Bunschoten, E.P.; Cnossen, M.H.; Bom, J.G. van der; Eikenboom, J.; Leebeek, F.W.G.; Fijnvandraat, K.; Coppens, M.; Kors, A.; Zweegman, S.; Meris, J. de; Goverde, G.J.; Jonkers, M.H.; Dors, N.; Nijziel, M.R.; Nieuwenhuizen, L.; Meijer, K.; Tamminga, R.Y.J.; Linden, P.W. van der; Ypma, P.F.; Eikenboom, H.C.J.; Bom, J.G. van der; Smiers, F.J.W.; Granzen, B.; Hamulyak, K.; Brons, P.; Laros-van Gorkom, B.A.P.; Leebeek, F.W.G.; Cnossen, M.H.; Atiq, F.; Mauser-Bunschoten, E.P.; Galen, K.P.M. van & WIN Study Grp (2019), BMI is an important determinant of VWF and FVIII levels and bleeding phenotype in patients with von Willebrand disease.
- Henriquez, D.D.C.A.; Caram-Deelder, C.; Cessie, S. le; Zwart, J.J.; Roosmalen, J.J.M. van; Eikenboom, J.C.J.; So-Osman, C.; Watering, L.G. van de; Zwaginga, J.J.; Koopman-van Gemert, A.W.M.M.; Bloemenkamp, K.W.M.; Bom, J.G. van der; Bank, C.M.C.; Snuif-de Lange, Y.S.; Gammeren, A.J. van; Papatsonis, D.N.M.; Klinkspoor, H.; Kok, M.; Boer, B.A. de; Langenveld, J.; Leers, M.P.G.; Diris, J.H.C.; Kok, R.D.; Engbers, P.; Hanssen, M.J.C.P.; Wijngaarden, W.J. van; Schippers, D.H.; Stappen, J.J. van der; Hasaart, T.H.M.; Kerkhof, D.H. van de; Kok, J.B. de; Unnik, G.A. van; Kortlandt, W.; Schuitemaker, N.E.; Delemarre, F.M.C.; Duijnhoven, H.L.P. van; Duvekot, H.J.; Hogenboom, S.; Kleiverda, G.; Etten-van Hulst, M.J.W. van; Mirani-Oostdijk, K.P.; Kampen, C. van; Weinans, M.J.N.; Adriaanse, H.J.; Huisjes, A.J.M.; Frasa, M.A.M.; Keuren, J.F.W.; Meir, C.A. van; Feitsma, H.; Hudig, F.; Sikkema, J.M.; Baas, M.I.; Fouraux, M.A.; Hmetz, G.C.; Bijvank, B.H.N.; Rondeel, H.J.M.; Roelofsen, J.M.T.; Doesburg-van Kleffens, M.; Wit, S.C. de; Versendaal, H.; Weerkamp, F.; Henskens, Y.M.C.; Scheepers, L.H.C.J.; Ham, D.P. van der; Smit, J.W.; Graaf, F. van der; Porath, M.M.; Salm, P.C.M. van der; Wijnen, M. van; Pontesilli, M.; Dunne, F.M. van; Ponjee, G.A.E.; Post, M.S.; Veen, B.S. van der; Brons, J.T.J.; Slomp, J.; Mare, A. de; Leyte, A.; Akker, E.S.A. van den; Wet, H. de; Borden, D.M.R. van der; Bremer, H.A.; Tax, G.H.M.; Vries, M.J. de; Boer, K. de; Waard, H. de; Keijzer, R.H. de; Burggraaff, J.M.; Pouwels, J.G.J.; Gemund, N. van; Prinzen, L.; Hendriks, H.A.; Hermsen, B.B.J.; Koehorst, S.G.A.; Verhagen, T.E.M.; Beek, E. van; Hackeng, C.M.; Kabel, P.J.; Steures, P.; Dooren, I.A. van; Michielse, E.C.H.J.; Chon, H.; Treskes, M.; Visser, H.; Oostenveld, E.; Peters, D.H.M.; Franssen, M.T.M.; Meekers, J.H.; Woiski, M.D.; Pampus, L.C.M. van; Oudijk, M.A.; Vooght, K.M.K. de; Cikot, R.L.M.; Mostert, L.J.; Ceelie, H.; Huijssoon, A.M.G.; Groot, C.J.M. de; Visser, O.; Jonker, N.; Koops, A.; Hooker, A.; Osmanovic, N.; Ulenkate, H.J.L.M.; Visschers, B.; Keuren, J.F.W.; Martens, G.D.M. & TeMpOH-Res Grp (2019), Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage, Jama Network Open 2(11).
- Magro-Checa, C.; Kumar, S.; Ramiro, S.; Beaart-van de Voorde, L.J.; Eikenboom, J.; Ronen, I.; Bresser, J. de; Buchem, M.A. van; Huizinga, T.W. & Steup-Beekman, G.M. (2019), Are serum autoantibodies associated with brain changes in systemic lupus erythematosus? MRI data from the Leiden NP-SLE cohort, Lupus 28(1): 94-103.
- Atiq, F.; Mauser-Bunschoten, E.P.; Eikenboom, J.; Galen, K.P.M. van; Meijer, K.; Meris, J. de; Cnossen, M.H.; Beckers, E.A.M.; Laros-van Gorkom, B.A.P.; Nieuwenhuizen, L.; Bom, J.G. van der; Fijnvandraat, K.; Leebeek, F.W.G. & WiN Study Grp (2019), Sports participation and physical activity in patients with von Willebrand disease, Haemophilia 25(1): 101-108.
- Gillissen, A.; Akker, T. van den; Caram-Deelder, C.; Henriquez, D.D.C.A.; Bloemenkamp, K.W.M.; Roosmalen, J.J.M. van; Eikenboom, J.; Bom, J.G. van der & TeMpOH-1 study Grp (2018), Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study, BMC Pregnancy and Childbirth 18.
- Jong, A. de; Dirven, R.J.; Oud, J.A.; Tio, D.; Vlijmen, B.J.M. van & Eikenboom, J. (2018), Correction of a dominant-negative von Willebrand factor multimerization defect by small interfering RNA-mediated allele-specific inhibition of mutant von Willebrand factor, Journal of Thrombosis and Haemostasis 16(7): 1357-1368.
- Hazendonk, H.C.A.M.; Heijdra, J.M.; Jager, N.C.B. de; Veerman, H.C.; Boender, J.; Moort, I. van; Mathot, R.A.A.; Meijer, K.; Laros-van Gorkom, B.A.P.; Eikenboom, J.; Fijnvandraat, K.; Leebeek, F.W.G.; Cnossen, M.H. & OPTI-CLOT WIN Study Grp (2018), Analysis of current perioperative management with Haemate((R)) P/Humate P-(R) in von Willebrand disease: Identifying the need for personalized treatment, Haemophilia 24(3): 460-470.
- Teng, Y.K.O.; Bredewold, E.O.W.; Rabelink, T.J.; Huizinga, T.W.J.; Eikenboom, H.C.J.; Limper, M.; Fritsch-Stork, R.D.E.; Bloemenkamp, K.W.M. & Sueters, M. (2018), An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus, Rheumatology 57(10): 1707-1720.
- Groeneveld, D.J.; Sanders, Y.V.; Adelmeijer, J.; Mauser-Bunschoten, E.P.; Bom, J.G. van der; Cnossen, M.H.; Fijnvandraat, K.; Laros-van Gorkom, B.A.P.; Meijer, K.; Lisman, T.; Eikenboom, J. & Leebeek, F.W.G. (2018), Circulating Angiogenic Mediators in Patients with Moderate and Severe von Willebrand Disease: A Multicentre Cross-Sectional Study, Thrombosis and Haemostasis 118(1): 152-160.
- Boender, J.; Eikenboom, J.; Bom, J.G. van der; Meijer, K.; Meris, J. de; Fijnvandraat, K.; Cnossen, M.H.; Laros-van Gorkom, B.A.P.; Heerde, W.L. van; Mauser-Bunschoten, E.P.; Maat, M.P.M. de; Leebeek, F.W.G. & WiN Study Grp (2018), Clinically relevant differences between assays for von Willebrand factor activity, Journal of Thrombosis and Haemostasis 16(12): 2413-2424.
- Gillissen, A.; Akker, T. van den; Caram-Deelder, C.; Henriquez, D.D.C.A.; Bloemenkamp, K.W.M.; Maat, M.P.M. de; Roosmalen, J.J.M. van; Zwart, J.J.; Eikenboom, J.; Bom, J.G. van der & TeMpOH-1 Study Grp (2018), Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study, Blood Advances 2(19): 2433-2442.
- Atiq, F.; Meijer, K.; Eikenboom, J.; Fijnvandraat, K.; Mauser-Bunschoten, E.P.; Galen, K.P.M. van; Nijziel, M.R.; Ypma, P.F.; Meris, J. de; Laros-van Gorkom, B.A.P.; Bom, J.G. van der; Maat, M.P. de; Cnossen, M.H.; Leebeek, F.W.G. & WiN Study Grp (2018), Comorbidities associated with higher von Willebrand factor (VWF) levels may explain the age-related increase of VWF in von Willebrand disease, British Journal of Haematology 182(1): 93-105.
- Galen, K.P.M. van; Timmer, M.; Kleijn, P. de; Leebeek, F.W.G.; Foppen, W.; Schutgens, R.E.G.; Eikenboom, J.; Meijer, K.; Fijnvandraat, K.; Laros-van Gorkom, B.A.P.; Twisk, J.W.; Mauser-Bunschoten, E.P.; Fischer, K. & WiN Studygrp (2018), Long-Term Outcome after Joint Bleeds in Von Willebrand Disease Compared to Haemophilia A: A Post Hoc Analysis, Thrombosis and Haemostasis 118(10): 1690-1700.
- Mufti, A.H.; Ogiwara, K.; Swystun, L.L.; Eikenboom, J.C.J.; Budde, U.; Hopman, W.M.; Hallden, C.; Goudemand, J.; Peake, I.R.; Goodeve, A.C.; Lillicrap, D.; Hampshire, D.J.; European Grp Willebrand Dis EU-VWD & Zimmerman Program Mol Clinical Bio (2018), The common VWF single nucleotide variants c.2365A>G and c.2385T>C modify VWF biosynthesis and clearance, Blood Advances 2(13): 1585-1594.
- Jong, A. de; Dirven, R.J.; Oud, J.A.; Tio, D.; Vlijmen, B.J.M. van & Eikenboom, J. (2018), Correction of a dominant-negative von Willebrand factor multimerization defect by small interfering RNA-mediated allele-specific inhibition of mutant von Willebrand factor, Journal of Thrombosis and Haemostasis 16(7).
- Magro-Checa, C.; Zirkzee, E.J.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.; Wee, N.J. van der; Huisman, M.V.; Eikenboom, J.; Kruyt, N.D.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort, Rheumatology 56(10): 1676-1683.
- Jong, A. de & Eikenboom, J. (2017), Von Willebrand disease mutation spectrum and associated mutation mechanisms, Thrombosis Research 159: 65-75.
- Gillissen, A.; Henriquez, D.D.C.A.; Akker, T. van den; Cararn-Deelder, C.; Winds, M.; Zwart, J.J.; Roosmalen, J. van; Eikenboom, J.; Eloernenkamp, K.W.M.; Bom, J.G. van der & TeMpOH-1 Study Grp (2017), The effect of tranexamic acid on blood loss and maternal outcome in the treatment of persistent postpartum hemorrhage: A nationwide retrospective cohort study, PLoS ONE 12(11).
- Abdul, S.; Boender, J.; Malfliet, J.J.M.C.; Eikenboom, J.; Draat, K.F. van; Mauser-Bunschoten, E.P.; Meijer, K.; Meris, J. de; Laros-van Gorkom, B.A.P.; Bom, J.G. van der; Leebeek, F.W.G.; Rijken, D.C.; Willige, S.U. de & Study Grp (2017), Plasma levels of plasminogen activator inhibitor-1 and bleeding phenotype in patients with von Willebrand disease, Haemophilia 23(3): 437-443.
- Galen, K.P.M. van; Kleijn, P. de; Foppen, W.; Eikenboom, J.; Meijer, K.; Schutgens, R.E.G.; Fischer, K.; Cnossen, M.H.; Meris, J. de; Fijnvandraat, K.; Bom, J.G. van der; Laros-van Gorkom, B.A.P.; Leebeek, F.W.G.; Mauser-Bunschoten, E.P. & Win Study Grp (2017), Long-term impact of joint bleeds in von Willebrand disease: a nested case-control study, Haematologica 102(9): 1486-1493.
- Mourik, M. & Eikenboom, J. (2017), Lifecycle of Weibel-Palade bodies, H�mostaseologie 37(1): 13-24.
- Galen, K.P.M. van; Timmer, M.A.; Kleijn, P. de; Fischer, K.; Foppen, W.; Schutgens, R.E.G.; Eikenboom, J.; Meijer, K.; Cnossen, M.H.; Fijnvandraat, K.; Bom, J.G. van der; Laros-van Gorkom, B.A.P.; Leebeek, F.W.G.; Mauser-Bunschoten, E.P. & Win Study Grp (2017), Joint assessment in von Willebrand disease Validation of the Haemophilia Joint Health score and Haemophilia Activities List, Thrombosis and Haemostasis 117(8): 1465-1470.
- Hout, F.M.A. van; Bontekoe, I.J.; Laleijne, L.A.E. de; Kerkhoffs, J.L.; Korte, D. de; Eikenboom, J.; Bom, J.G. van der & Meer, P.F. van der (2017), Comparison of haemostatic function of PAS-C-platelets vs. plasma-platelets in reconstituted whole blood using impedance aggregometry and thromboelastography, Vox Sanguinis 112(6): 549-556.
- Pelzer, N.; Bijkerk, R.; Reinders, M.; Zonneveld, A.J. van; Ferrari, M.; Maagdenberg, A. van den; Eikenboom, J. & Terwindt, G. (2017), Circulating endothelial markers in the monogenic small vessel disease retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations, European Journal of Neurology 24: 35-35.
- Pelzer, N.; Bijkerk, R.; Reinders, M.E.J.; Zonneveld, A.J. van; Ferrari, M.D.; Maagdenberg, A.M.J.M. van den; Eikenboom, J. & Terwindt, G.M. (2017), Circulating Endothelial Markers in Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations, Stroke 48(12): 3301-3307.
- Magro-Checa, C.; Zirkzee, E.J.; Beaart-van de Voorde, L.J.J.; Middelkoop, H.A.; Wee, N.J. van der; Huisman, M.V.; Eikenboom, J.; Kruyt, N.D.; Buchem, M.A. van; Huizinga, T.W.J. & Steup-Beekman, G.M. (2017), Value of multidisciplinary reassessment in attribution of neuropsychiatric events to systemic lupus erythematosus: prospective data from the Leiden NPSLE cohort, Rheumatology.
- Roeleveld, P.P.; Hoeven, A. van der; Wilde, R.B.P. de; Eikenboom, J.; Smiers, F.J. & Bunker-Wiersma, H.E. (2016), Higher Tinzaparin Dosing Is Needed to Achieve Target Anti-Xa Levels in Pediatric Cardiac Intensive Care Patients, Pediatric Critical Care Medicine 17(3): 203-209.
- Leebeek, F.W.G. & Eikenboom, J.C.J. (2016), Von Willebrand's Disease, New England Journal of Medicine 375(21): 2067-2080.
- James, A.H.; Eikenboom, J. & Federici, A.B. (2016), State of the art: von Willebrand disease, Haemophilia 22: 54-59.
- Galen, K.P.M. van; Meijer, K.; Vogely, H.C.; Eikenboom, J.; Schutgens, R.E.G.; Cnossen, M.H.; Fijnvandraat, K.; Bom, J.G. van der; Laros-van Gorkom, B.A.P.; Leebeek, F.W.G.; Mauser-Bunschoten, E.P. & Win Study Grp (2016), Joint surgery in von Willebrand disease: a multicentre cross-sectional study, Haemophilia 22(2): 256-262.
- Gielen, C.L.I.; Brand, A.; Heerde, W.L. van; Stijnen, T.; Klautz, R.J.M. & Eikenboom, J. (2016), Hemostatic alterations during coronary artery bypass grafting, Thrombosis Research 140: 140-146.
- Hulle, T. van der; Exter, P.L. den; Hoven, P. van den; Hoeven, J.J. van der; Meer, F.J.M. van der; Eikenboom, J.; Huisman, M.V. & Klok, F.A. (2016), Cohort Study on the Management of Cancer-Associated Venous Thromboembolism Aimed at the Safety of Stopping Anticoagulant Therapy in Patients Cured of Cancer, Chest 149(5): 1245-1251.
- Jong, A. de & Eikenboom, J. (2016), Developments in the diagnostic procedures for von Willebrand disease, Journal of Thrombosis and Haemostasis 14(3): 449-460.
- Sanders, Y.V.; Groeneveld, D.; Meijer, K.; Fijnvandraat, K.; Cnossen, M.H.; Bom, J.G. van der; Coppens, M.; Meris, J. de; Laros-van Gorkom, B.A.P.; Mauser-Bunschoten, E.P.; Leebeek, F.W.G.; Eikenboom, J. & WiN Study Grp (2015), von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease, Blood 125(19): 3006-3013.
- Mourik, M.J.; Faas, F.G.A.; Zimmermann, H.; Eikenboom, J. & Koster, A.J. (2015), Towards the imaging of Weibel-Palade body biogenesis by serial block face-scanning electron microscopy, Journal of Microscopy 259(2): 97-104.
- Henriquez, D.D.; Bloemenkamp, K.W.; Cessie, S. le; Zwart, J.; Roosmalen, J. van; Eikenboom, J.; So-Osman, C.; Watering, L. van de; Zwaginga, J.J.; Bom, J.G. van der & TeMpOH-1 Study Grp (2015), Timing of plasma transfusion and maternal mortality and severe maternal morbidity in women with persistent postpartum haemorrhage: the Tempoh-1 study, Journal of Thrombosis and Haemostasis 13: 86-86.
- Gielen, C.L.I.; Bruggemans, E.F.; Stijnen, T.; Eikenboom, J.; Tavilla, G.; Brand, A. & Klautz, R.J.M. (2015), Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?, European Journal of Cardio-Thoracic Surgery 48(4): E64-E70.
- Hulle, T.V.D.; Exter, P.L. den; Hoven, P. van den; Hoeven, J.J. van der; Meer, F.J. van der; Eikenboom, J.; Huisman, M.V. & Klok, F.A. (2015), Safety of stopping anticoagulant treatment for cancer-associated venous thromboembolism after reaching complete remission from cancer, Journal of Thrombosis and Haemostasis 13: 987-987.
- Hulle, T. van der; Tan, M.; Exter, P.L. den; Roosmalen, M.J.G. van; Meer, F.J.M. van der; Eikenboom, J.; Huisman, M.V. & Klok, F.A. (2015), Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism, Haematologica 100(2): 188-193.
- Stoof, S.C.M.; Steenbergen, H.W. van; Zwagemaker, A.; Sanders, Y.V.; Cannegieter, S.C.; Duvekot, J.J.; Leebeek, F.W.G.; Peters, M.; Kruip, M.J.H.A. & Eikenboom, J. (2015), Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey, Haemophilia 21(4): 505-512.
- Bodo, I.; Eikenboom, J.; Montgomery, R.; Patzke, J.; Schneppenheim, R.; Paola, J. di & Subcomm Von Willebrand Factor (2015), Platelet-dependent von Willebrand factor activity. Nomenclature and methodology: communication from the SSC of the ISTH, Journal of Thrombosis and Haemostasis 13(7): 1345-1350.
- Groeneveld, D.J.; Bekkum, T. van; Cheung, K.L.; Dirven, R.J.; Castaman, G.; Reitsma, P.H.; Vlijmen, B. van & Eikenboom, J. (2015), No evidence for a direct effect of von Willebrand factor's ABH blood group antigens on von Willebrand factor clearance, Journal of Thrombosis and Haemostasis 13(4): 592-600.
- Galen, K.P.M. van; Sanders, Y.V.; Vojinovic, U.; Eikenboom, J.; Cnossen, M.H.; Schutgens, R.E.G.; Bom, J.G. van der; Fijnvandraat, K.; Laros-Van Gorkom, B.A.P.; Meijer, K.; Leebeek, F.W.G.; Mauser-Bunschoten, E.P. & Win Study Grp (2015), Joint bleeds in von Willebrand disease patients have significant impact on quality of life and joint integrity: a cross-sectional study, Haemophilia 21(3): E185-E192.
- Van Heerde W., van Puffelen J., Kloots I, Boender J., Sanders Y., Cnossen M., Laros-van Gorkom B., Fijnvandraat K., Schoormans S., van der Bom J., Meijer K., Mauser-Bunschoten E., Eikenboom J., Kiemeney L. & Leebeek F. (2015), Impact of annexin A2 SNP on von Willebrand factor levels in patients with moderate and severe von Willebrand disease, Journal of Thrombosis and Haemostasis 13: 172-173.
- Boender J., Sanders Y., van Heerde W., Cnossen M., van Gorkom B. L., Fijnvandraat K., Schoormans S., Dors N., van der Bom J., Meijer K., Mauser-Bunschoten E., Eikenboom J. & Leebeek F. (2015), Genotyping of VWD patients in the netherlands: phenotype-genotype discrepancies and 27 novel VWF gene mutations, Journal of Thrombosis and Haemostasis 13: 101-101.
- Baaij, M.; Galen, K.P.M. van; Urbanus, R.T.; Nigten, J.; Eikenboom, J.H.C. & Schutgens, R.E.G. (2015), First report of inhibitory von Willebrand factor alloantibodies in type 2B von Willebrand disease, British Journal of Haematology 171(3): 424-427.
- Mourik, M.J.; Faas, F.G.A.; Zimmermann, H.; Voorberg, J.; Koster, A.J. & Eikenboom, J. (2015), Content delivery to newly forming Weibel-Palade bodies is facilitated by multiple connections with the Golgi apparatus, Blood 125(22): 3509-3516.
- Sanders, Y.V.; Bom, J.G. van der; Isaacs, A.; Cnossen, M.H.; Maat, M.P.M. de; Laros-van Gorkom, B.A.P.; Fijnvandraat, K.; Meijer, K.; Duijn, C.M. van; Mauser-Bunschoten, E.P.; Eikenboom, J.; Leebeek, F.W.G. & Win Study Grp (2015), CLEC4M and STXBP5 gene variations contribute to vonWillebrand factor level variation in von Willebrand disease, Journal of Thrombosis and Haemostasis 13(6): 956-966.
- Kooiman, J.; Exter, P.L. den; Kilicsoy, I.; Cannegieter, S.C.; Eikenboom, J.; Huisman, M.V.; Klok, F.A. & Versteeg, H.H. (2015), Association between micro particle-tissue factor activity, factor VIII activity and recurrent VTE in patients with acute pulmonary embolism, Journal of Thrombosis and Thrombolysis 40(3): 323-330.
- Groeneveld, D.J.; Bekkum, T.; Dirven, R.J.; Wang, J.W.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2015), Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease, Journal of Thrombosis and Haemostasis 13(10): 1854-1866.
- Bonten, T.N.; Snoep, J.D.; Assendelft, W.J.J.; Zwaginga, J.J.; Eikenboom, J.; Huisman, M.V.; Rosendaal, F.R. & Bom, J.G. van der (2015), Time-Dependent Effects of Aspirin on Blood Pressure and Morning Platelet Reactivity A Randomized Cross-Over Trial, Hypertension 65(4): 743-750.
- Pollack Jr, C.V.; Reilly, P.A.; Eikelboom, J.; Glund, S.; Verhamme, P.; Bernstein, R.A.; Dubiel, R.; Huisman, M.V.; Hylek, E.M.; Kamphuisen, P.W.; Kreuzer, J.; Levy, J.H.; Sellke, F.W.; Stangier, J.; Steiner, T.; Wang, B.; Kam, C.W. & Weitz, J.I. (2015), Idarucizumab for Dabigatran Reversal, New England Journal of Medicine 373(6): 511-520.
- Sanders, Y.V.; Laros-Van Gorkom, B.A.P.; Meijer, K.; Bom, J.G. van der; Cnossen, M.H.; Nijziel, M.R.; Fijnvandraat, K.; Eikenboom, J.; Mauser-Bunschoten, E.P. & Leebeek, F.W.G. (2014), Von Willebrand disease and aging: an evolving phenotype, Haemophilia 20: 110-110.
- Hooren, K.W.E.M. van; Breevoort, D. van; Fernandez-Borja, M.; Meijer, A.B.; Eikenboom, J.; Bierings, R. & Voorberg, J. (2014), Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies, Journal of Thrombosis and Haemostasis 12(2): 273-281.
- Groeneveld, D.J.; Wang, J.W.; Mourik, M.J.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2014), Storage and secretion of naturally occurring von Willebrand factor A domain variants, British Journal of Haematology 167(4): 529-540.
- Breevoort, D. van; Snijders, A.P.; Hellen, N.; Weckhuysen, S.; Hooren, K.W.E.M. van; Eikenboom, J.; Valentijn, K.; Fernandez-Borja, M.; Ceulemans, B.; Jonghe, P. de; Voorberg, J.; Hannah, M.; Carter, T. & Bierings, R. (2014), STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a, Blood 123(20): 3185-3194.
- Sanders, Y.V.; Giezenaar, M.A.; Laros-van Gorkom, B.A.P.; Meijer, K.; Bom, J.G. van der; Cnossen, M.H.; Nijziel, M.R.; Ypma, P.F.; Fijnvandraat, K.; Eikenboom, J.; Mauser-Bunschoten, E.P.; Leebeek, F.W.G. & WIN STUDY Grp (2014), von Willebrand disease and aging: an evolving phenotype, Journal of Thrombosis and Haemostasis 12(7): 1066-1075.
- Bonten, T.N.; Saris, A.; Oostrom, M.J. van; Snoep, J.D.; Rosendaal, F.R.; Zwaginga, J.J.; Eikenboom, J.; Meer, P.F. van der & Bom, J.G. van der (2014), Effect of aspirin intake at bedtime versus on awakening on circadian rhythm of platelet reactivity A randomised cross-over trial, Thrombosis and Haemostasis 112(6): 1209-1218.
- Mourik, M.J.; Faas, F.G.A.; Valentijn, K.M.; Valentijn, J.A.; Eikenboom, J.C.; Koster, A.J.; MullerReichert, T. & Verkade, P. (2014), Correlative Light Microscopy and Electron Tomography to Study Von Willebrand Factor Exocytosis from Vascular Endothelial Cells, Methods in Cell Biology 124: 71-92.
- Hulle, T. van der; Tan, M.; Exter, P.L. den; Roosmalen, M.J.G. van; Meer, F.J.M. van der; Eikenboom, J.; Huisman, M.V. & Klok, F.A. (2014), Recurrence Risk after Limited Duration of Anticoagulant Treatment for Late Second Venous Thromboembolism, Blood 124(21).
- Gielen, C.; Dekkers, O.; Stijnen, T.; Schoones, J.; Brand, A.; Klautz, R. & Eikenboom, J. (2014), The effects of pre- and postoperative fibrinogen levels on blood loss after cardiac surgery: a systematic review and meta-analysis, Interactive Cardiovascular and Thoracic Surgery 18(3): 292-298.
- Mourik, M.J.; Faas, F.G.A.; Valentijn, K.M.; Valentijn, J.A.; Eikenboom, J.C.; Koster, A.J.; MullerReichert, T. & Verkade, P. (2014), Correlative Light Microscopy and Electron Tomography to Study Von Willebrand Factor Exocytosis from Vascular Endothelial Cells.
- Bonten, T.N.; Snoep, J.D.; Assendelft, W.J.; Zwaginga, J.J.; Huisman, M.V.; Rosendaal, F.R.; Eikenboom, J. & Bom, J.G. van (2013), Does Aspirin Intake at Bedtime Decrease Blood Pressure and Morning Peak of Platelet Reactivity?: A Randomized Cross-over Trial, Circulation 128(24): 2716-2716.
- Eikenboom, J.; Federici, A.B.; Dirven, R.J.; Castaman, G.; Rodeghiero, F.; Budde, U.; Schneppenheim, R.; Batlle, J.; Canciani, M.T.; Goudemand, J.; Peake, I.; Goodeve, A. & MCMDM-1VWD Study Grp (2013), VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease, Blood 121(12): 2336-2339.
- Valentijn, K.M. & Eikenboom, J. (2013), WeibelPalade bodies: a window to von Willebrand disease, Journal of Thrombosis and Haemostasis 11(4): 581-592.
- Sanders, Y.V.; Eikenboom, J.; Wee, E.M. de; Bom, J.G. van der; Cnossen, M.H.; Degenaar-Dujardin, M.E.L.; Fijnvandraat, K.; Kamphuisen, P.W.; Laros-Van Gorkom, B.A.P.; Meijer, K.; Mauser-Bunschoten, E.P.; Leebeek, F.W.G. & Win Study Grp (2013), Reduced prevalence of arterial thrombosis in von Willebrand disease, Journal of Thrombosis and Haemostasis 11(5): 845-854.
- Castaman, G.; Goodeve, A.; Eikenboom, J. & European Grp von Willebrand Dis (2013), Principles of care for the diagnosis and treatment of von Willebrand disease, Haematologica 98(5): 667-674.
- Wang, J.W.; Bouwens, E.A.M.; Pintao, M.C.; Voorberg, J.; Safdar, H.; Valentijn, K.M.; Boer, H.C. de; Mertens, K.; Reitsma, P.H. & Eikenboom, J. (2013), Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease, Blood 121(14): 2762-2772.
- Visser, M.C.H. de; Minkelen, R. van; Marion, V. van; Heijer, M. den; Eikenboom, J.; Vos, H.L.; Slagboom, P.E.; Houwing-Duistermaat, J.J.; Rosendaal, F.R. & Bertina, R.M. (2013), Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study, Journal of Thrombosis and Haemostasis 11(8): 1474-1484.
- Mourik, M.J.; Valentijn, J.A.; Voorberg, J.; Koster, A.J.; Valentijn, K.M. & Eikenboom, J. (2013), von Willebrand factor remodeling during exocytosis from vascular endothelial cells, Journal of Thrombosis and Haemostasis 11(11): 2009-2019.
- Navarrete, M.A.; Meer, F.J.M. van der; Damiani, G.; Diaz, A. & Eikenboom, J. (2012), The use of rituximab therapy in patients with acquired factor v inhibitors, American Journal of Hematology 87(8): 826-827.
- Blomback, M.; Eikenboom, J.; Lane, D.; Denis, C. & Lillicrap, D. (2012), von Willebrand disease biology, Haemophilia 18: 141-147.
- Breevoort, D. van; Agtmaal, E.L. van; Dragt, B.S.; Gebbinck, J.K.; Dienava-Verdoold, I.; Kragt, A.; Bierings, R.; Horrevoets, A.J.G.; Valentijn, K.M.; Eikenboom, J.C.; Fernandez-Borja, M.; Meijer, A.B. & Voorberg, J. (2012), Proteomic Screen Identifies IGFBP7 as a Novel Component of Endothelial Cell-Specific Weibel-Palade Bodies, Journal of Proteome Research 11(5): 2925-2936.
- Wee, E.M. de; Sanders, Y.V.; Mauser-Bunschoten, E.P.; Bom, J.G. van der; Degenaar-Dujardin, M.E.L.; Eikenboom, J.; Goede-Bolder, A. de; Laros-van Gorkom, B.A.P.; Meijer, K.; Hamulyak, K.; Nijziel, M.R.; Fijnvandraat, K.; Leebeek, F.W.G. & WiN Study Grp (2012), Determinants of bleeding phenotype in adult patients with moderate or severe von Willebrand disease, Thrombosis and Haemostasis 108(4): 683-692.
- Wang, J.W.; Valentijn, J.A.; Valentijn, K.M.; Dragt, B.S.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2012), Formation of platelet-binding von Willebrand factor strings on non-endothelial cells.
- Wang, J.W.; Groeneveld, D.J.; Cosemans, G.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2012), Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation, Haematologica 97(6): 859-866.
- Sanders, Y.V.; Eikenboom, J.C.; Wee, E.M. de; Bom, J.G. van der; Cnossen, M.H.; Degenaar-Dujardin, M.E.; Fijnvandraat, K.; Kamphuisen, P.W.; Laros-Van Gorkum, B.A.; Meijer, K.; Mauser-Bunschoten, E.P. & Leebeek, F.W. (2012), Von Willebrand disease protects against arterial thrombosis, Haemophilia 18: 45-46.
- Wee, E.M. de; Klaij, K.; Eikenboom, H.C.J.; Bom, J.G. van der; Fijnvandraat, K.; Laros-Van Gorkom, B.A.P.; Mauser-Bunschoten, E.P.; Meijer, K.; Goverde, G.; Linden, P.W.G. van der; Rijken, D.C.; Leebeek, F.W.G. & Win Study Grp (2012), Effect of fibrinolysis on bleeding phenotype in moderate and severe von Willebrand disease, Haemophilia 18(3): 444-451.
- Tosetto, A.; Castaman, G.; Plug, I.; Rodeghiero, F. & Eikenboom, J. (2011), Prospective evaluation of the clinical utility of quantitative bleeding severity assessment in patients referred for hemostatic evaluation.
- Wee, E.M. de; Knol, H.M.; Mauser-Bunschoten, E.P.; Bom, J.G. van der; Degenaar-Dujardin, M.E.L.; Eikenboom, J.C.J.; Fijnvandraat, K.; Goede-Bolder, A. de; Laros-van Gorkom, B.; Ypma, P.F.; Zweegman, S.; Meijer, K.; Leebeek, F.W.G. & WiN Study Grp (2011), Gynaecological and obstetric bleeding in moderate and severe Von Willebrand Disease, Thrombosis Research 127: S129-S129.
- Wee, E.M. de; Knol, H.M.; Mauser-Bunschoten, E.P.; Bom, J.G. van der; Eikenboom, J.C.J.; Fijnvandraat, K.; Goede-Bolder, A. de; Laros-van Gorkom, B.; Ypma, P.F.; Zweegman, S.; Meijer, K.; Leebeek, F.W.G. & WiN Study Grp (2011), Gynaecological and obstetric bleeding in moderate and severe von Willebrand disease, Thrombosis and Haemostasis 106(5): 885-892.
- Bouwens, E.A.M.; Mourik, M.J.; Biggelaar, M. van den; Eikenboom, J.C.J.; Voorberg, J.; Valentijn, K.M. & Mertens, K. (2011), Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies, Blood 118(22): 5947-5956.
- Hickson, N.; Hampshire, D.; Castaman, G.; Eikenboom, J.; Rodeghiero, F.; Peake, I.; Goodeve, A.; MCMDM-1VWD Study Grp & ZPMCB-VWD Study Grp (2011), Effect of the VWF promoter (GT)(n) repeat and single-nucleotide polymorphism c.-2527G > A on circulating von Willebrand factor levels under normal conditions.
- Wee, E.M. de; Klaij, K.; Eikenboom, J.; Bom, J. van der; Degenaar-Dujardin, M.; Fijnvandraat, K.; Goede-Bolder, A.; Laros-van Gorkom, B.; Mauser-Bunschoten, E.; Meijer, K.; Goverde, G.; Linden, P.W. van der; Rijken, D. & Leebeek, F. (2011), Effect of fibrinolysis on bleeding phenotype in moderate and severe.
- Wee, E.M. de; Leebeek, F.W.G. & Eikenboom, J.C.J. (2011), Diagnosis and Management of von Willebrand Disease in The Netherlands, Seminars in Thrombosis and Hemostasis 37(5): 480-487.
- Wee, E.M. de; Mauser-Bunschoten, E.; Bom, A. van der; Degenaar-Dujardin, M.; Eikenboom, J.; Goede-Bolder, D.; Laros-van Gorkom, B.; Meijer, K.; Hamulyak, K.; Nijziel, M.; Fijnvandraat, K. & Leebeek, F. (2011), Determinants of bleeding phenotype in patients with moderate or severe von Willebrand disease.
- Hampshire, D.J.; Cartwright, A.; Bloomer, L.D.; Al-Buhairan, A.M.; Vijzelaar, R.N.C.P.; Habart, D.; Hill, F.G.H.; Rodeghiero, F.; Budde, U.; Eikenboom, J.C.J.; Peake, I.R.; Goodeve, A.C.; EU-VWD Grp & ZPMCB-VWD Study Grp (2011), Copy number variation is a significant contributor to type 1 VWD pathogenesis in the EU MCMDM-1VWD cohort.
- Wang, J.W.; Bouwens, E.; Pintao, C.; Voorberg, J.; Valentijn, K.M.; Boer, H.C. de; Reitsma, P.H. & Eikenboom, J. (2011), Characterization of blood outgrowth endothelial cells derived from von Willebrand disease patients.
- Klok, F.A.; Surie, S.; Kempf, T.; Eikenboom, J.; Straalen, J.P. van; Kralingen, K.W. van; Dijk, A.P.J. van; Vliegen, H.W.; Bresser, P.; Wollert, K.C. & Huisman, M.V. (2011), A simple non-invasive diagnostic algorithm for ruling out chronic thromboembolic pulmonary hypertension in patients after acute pulmonary embolism, Thrombosis Research 128(1): 21-26.
- Wee, E.M. de; Fijnvandraat, K.; Goede-Bolder, A. de; Mauser-Bunschoten, E.P.; Eikenboom, J.C.J.; Brons, P.P.; Smiers, F.J.; Tamminga, R.; Oostenbrink, R.; Raat, H.; Bom, J.G. van der; Leebeek, F.W.G. & WiN Study Grp (2011), Impact of von Willebrand disease on health-related quality of life in a pediatric population, Journal of Thrombosis and Haemostasis 9(3): 502-509.
- Valentijn, K.M.; Sadler, J.E.; Valentijn, J.A.; Voorberg, J. & Eikenboom, J. (2011), Functional architecture of Weibel-Palade bodies, Blood 117(19): 5033-5043.
- Kortekaas, K.A.; Eikenboom, J.; Stokkel, M.P.M.; Gent, H. van; Roos, A. de & Huisman, M.V. (2011), Is a V/Q scan based algorithm correctly used to diagnose acute pulmonary embolism? A daily practice survey, Thrombosis Research 128(3): 221-226.
- Wang, J.W.; Valentijn, K.M.; Boer, H.C. de; Dirven, R.J.; Zonneveld, A.J. van; Koster, A.J.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2011), Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease, Journal of Biological Chemistry 286(27): 24180-24188.
- Klok, F.A.; Surie, S.; Kempf, T.; Eikenboom, J.; Stralen, J. van; Kralingen, K. van; Dijk, A. van; Vliegen, H.; Bresser, P.; Wollert, K. & Huisman, M. (2011), A simple non-invasive diagnostic algorithm for ruling out chronic thromboembolic pulmonary hypertension in patients after acute pulmonary embolism.
- Tosetto, A.; Rodeghiero, F.; Castaman, G.; Goodeve, A.; Federici, A.B.; Batlle, J.; Meyer, D.; Goudemand, J.; Eikenboom, J.; Schneppenheim, R.; Budde, U.; Ingerslev, J.; Lethagen, S.; Hill, F.G.H. & Peake, I. (2011), A comparison between two semi-quantitative bleeding scales for the diagnosis and assessment of bleeding severity in type 1 von Willebrand disease, Haemophilia 17(1): 165-166.
- Wang, J.W.; Groeneveld, D.J.; Cosemans, G.; Dirven, R.J.; Valentijn, K.M.; Voorberg, J.; Reitsma, P.H. & Eikenboom, J. (2011), Biogenesis of Weibel-Palade bodies in von Willebrand disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.
- Snoep, J.D.; Eikenboom, J.C.J.; Zwaginga, J.J.; Roest, M.; Patrono, C.; Rocca, B.; Petrucci, G.; Rosendaal, F.R. & Bom, J.G. van der (2011), Platelet reactivity and recurrent cardiovascular events in patients with stable cardiovascular disease using aspirin: a head-to-head comparison of different tests.
- Nossent, A.Y.; Robben, J.H.; Deen, P.M.T.; Vos, H.L.; Rosendaal, F.R.; Doggen, C.J.M.; Hansen, J.L.; Sheikh, S.P.; Bertina, R.M. & Eikenboom, J.C.J. (2010), Functional variation in the arginine vasopressin 2 receptor as a modifier of human plasma von Willebrand factor levels, Journal of Thrombosis and Haemostasis 8(7): 1547-1554.
- Hampshire, D.J.; Burghel, G.J.; Goudemand, J.; Bouvet, L.C.S.; Eikenboom, J.C.J.; Schneppenheim, R.; Budde, U.; Peake, I.R.; Goodeve, A.C.; EU-VWD Grp & ZPMCB-VWD Study Grp (2010), Polymorphic variation within the VWF gene contributes to the failure to detect mutations in patients historically diagnosed with type 1 von Willebrand disease from the MCMDM-1VWD cohort, Haematologica 95(12): 2163-2165.
- Hampshire, D.J.; Bloomer, L.D.; Al-Buhairan, A.M.; Coyle, R.E.; Vijzelaar, R.N.C.P.; Lillicrap, D.; James, P.D.; Eikenboom, J.C.J.; Schneppenheim, R.; Rodeghiero, F.; Montgomery, R.R.; Peake, I.R. & Goodeve, A.C. (2010), Investigation of the Role of Copy Number Variation In the Pathogenesis of Type 1 Von Willebrand Disease., Blood 116(21): 913-913.
- Hickson, N.; Hampshire, D.; Winship, P.; Goudemand, J.; Schneppenheim, R.; Budde, U.; Castaman, G.; Rodeghiero, F.; Federici, A.B.; James, P.; Peake, I.; Eikenboom, J.; Goodeve, A.; MCMDM-VWD Grp & ZPMCB -VWD Study Grp (2010), von Willebrand factor variant p.Arg924Gln marks an allele associated with reduced von Willebrand factor and factor VIII levels, Journal of Thrombosis and Haemostasis 8(9): 1986-1993.
- Wang, J.W. & Eikenboom, J. (2010), Von Willebrand disease and Weibel-Palade bodies, H�mostaseologie 30(3): 150-155.
- Castaman, G.; Tosetto, A.; Goodeve, A.; Federici, A.B.; Lethagen, S.; Budde, U.; Batlle, J.; Meyer, D.; Mazurier, C.; Goudemand, J.; Eikenboom, J.; Schneppenheim, R.; Ingerslev, J.; Habart, D.; Hill, F.; Peake, I. & Rodeghiero, F. (2010), The impact of bleeding history, von Willebrand factor and PFA-100 (R) on the diagnosis of type 1 von Willebrand disease: results from the European study MCMDM-1VWD, British Journal of Haematology 151(3): 245-251.
- Nossent, A.Y.; Ellenbroek, J.H.; Frolich, M.; Bertina, R.M.; Knoers, N.V.A.M. & Eikenboom, J.C.J. (2010), Plasma levels of von Willebrand factor, von Willebrand factor propeptide and factor VIII in carriers and patients with nephrogenic diabetes insipidus, Thrombosis Research 125(6): 554-556.
- Castaman, G.; Tosetto, A.; Eikenboom, J.C. & Rodeghiero, F. (2010), Blood group significantly influences von Willebrand factor increase and half-life after desmopressin in von Willebrand disease Vicenza, Journal of Thrombosis and Haemostasis 8(9): 2078-2080.
- Wee, E. de; Knol, M.; Mauser-Bunschoten, E.; Bom, A. van der; Degenaar-Dujardin, M.; Eikenboom, J.C.J.; Fijnvandraat, K.; Goede-Bolder, A. de; Laros-van Gorkom, B.; Ypma, P.; Zweegman, S.; Meijer, K. & Leebeek, F.W.G. (2010), Women with Moderate and Severe Von Willebrand Disease Have a High Morbidity of Gynecological and Obstetric Bleeding, Blood 116(21): 241-241.
- Castaman, G.; Tosetto, A.; Cappelletti, A.; Goodeve, A.; Federici, A.B.; Batlle, J.; Meyer, D.; Goudemand, J.; Eikenboom, J.C.J.; Schneppenheim, R.; Budde, U.; Ingerslev, J.; Lethagen, S.; Hill, F.; Peake, I.R. & Rodeghiero, F. (2010), Validation of a rapid test (VWF-LIA) for the quantitative determination of von Willebrand factor antigen in type 1 von Willebrand disease diagnosis within the European multicenter study MCMDM-1VWD, Thrombosis Research 126(3): 227-231.
- Snoep, J.D.; Gaussem, P.; Eikenboom, J.C.J.; Emmerich, J.; Zwaginga, J.J.; Holmes, C.E.; Vos, H.L.; Groot, P.G. de; Herrington, D.M.; Bray, P.F.; Rosendaal, F.R. & Bom, J.G. van der (2010), The minor allele of GP6 T13254C is associated with decreased platelet activation and a reduced risk of recurrent cardiovascular events and mortality: results from the SMILE-Platelets project, Journal of Thrombosis and Haemostasis 8(11): 2377-2384.
- Wee, E.M. de; Mauser-Bunschoten, E.P.; Bom, J.G. van der; Degenaar-Dujardin, M.E.L.; Eikenboom, H.C.J.; Fijnvandraat, K.; Goede-Bolder, A. de; Laros-Van Gorkom, B.A.P.; Meijer, K.; Raat, H.; Leebeek, F.W.G. & WIN Study Grp (2010), Health-related quality of life among adult patients with moderate and severe von Willebrand disease, Journal of Thrombosis and Haemostasis 8(7): 1492-1499.
- Wee, E. de; Fijnvandraat, K.; Goede-Bolder, A. de; Mauser-Bunschoten, E.; Eikenboom, H.; Brons, P.; Smiers, F.; Tamminga, R.; Bom, J. van der & Leebeek, F. (2010), IMPACT OF VON WILLEBRAND DISEASE ON HEALTH RELATED QUALITY OF LIFE IN A PEDIATRIC POPULATION, Haematologica 95: 71-71.
- Rodriguez, P.G.; Eikenboom, H.C.J.; Tesselaar, M.E.T.; Huisman, M.V.; Nijkeuter, M.; Osanto, S. & Bertina, R.M. (2010), Plasma levels of microparticle-associated tissue factor activity in patients with clinically suspected pulmonary embolism, Thrombosis Research 126(4): 345-349.
- Berkhof FF & Eikenboom JC (2009), Efficacy of recombinant activated Factor VII in patients with massive uncontrolled bleeding: a retrospective observational analysis, Transfusion 49(3): 570-577.
- Eikenboom J, Hilbert L, Ribba AS, Hommais A, Habart D, Messenger S, Al-Buhairan A, Guilliatt A, Lester W & Mazurier C (2009), Expression of 14 von Willebrand factor mutations identified in patients with type 1 von Willebrand disease from the MCMDM-1VWD study, Journal of Thrombosis and Haemostasis 7(8): 1304-1312.
- Tripodi, A. & Besselaar, A. van den (2009), Laboratory Monitoring of Anticoagulation: Where Do We Stand?, Seminars in Thrombosis and Hemostasis 35(1): 34-41.
- Bezemer ID, van der Meer FJM, Eikenboom JCJ, Rosendaal FR & Doggen CJM (2009), The Value of Family History as a Risk Indicator for Venous Thrombosis, Archives of Internal Medicine -New Series- 169(6): 610-615.
- Nossent, A.Y.; Vos, H.L.; Rosendaal, F.R.; Bertina, R.M. & Eikenboom, J.C.J. (2008), Aquaporin 2 gene variations, risk of venous thrombosis and plasma levels of von Willebrand factor and factor VIII, Haematologica 93(6).
- Haberichter, S.L.; Castarnan, G.; Budde, U.; Peake, I.; Goodeve, A.; Rodeghiero, F.; Federici, A.B.; Batlle, J.; Meyer, D.; Mazurier, C.; Goudemand, J.; Eikenboom, J.; Schneppenheim, R.; Ingerslev, J.; Vorlova, Z.; Habart, D.; Holmberg, L.; Lethagen, S.; Pasi, J.; Hill, F.G.H. & Montgomery, R.R. (2008), Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: Molecular and Clinical Markers for the Diagnosis and Management of Type 1 VWD (MCMDM-1VWD), Blood 111(10).
- Kerkhoffs, J.L.H.; Eikenboom, J.Q.; Watering, L.M.G. van de; Wordragen-Vlaswinkel, R. van; Wijermans, P.W. & Brand, A. (2008), The clinical impact of platelet refractoriness: correlation with bleeding and survival, Transfusion 48(9).
- De Wee E, Mauser-Bunschoten E, Novakova I, Eikenboom H, Van Draat KF & Leebeek F (2008), Von Willebrand in the Netherlands: the WiN study. Background and study design, Haemophilia 14.
- Klok FA, Djurabi RK, Nijkeuter M, Eikenboom HCJ, Leebeek FWG, Kramer MHH, Kaasjager K, Kamphuisen PW, Buller HR & Huisman MV (2008), High D-dimer level is associated with increased 15-d and 3 months mortality through a more central localization of pulmonary emboli and serious comorbidity, British Journal of Haematology 140(2).
- Nossent AY, Van Marion V, Van Tilburg NH, Rosendaal FR, Bertina RM, Van Mourik JA & Eikenboom HCJ (2006), von Willebrand factor and its propeptide: the influence of secretion and clearance on protein levels and the risk of venous thrombosis, Journal of Thrombosis and Haemostasis 4(12).
- So-Osman C, Nelissen RGHH, Eikenboom HCJ & Brand A (2006), Efficacy, safety and user-friendliness of two devices for postoperative autologous shed red blood cell re-infusion in elective orthopaedic surgery patients: a randomized pilot study, Transfusion Medicine 16(5).
- van der Helm-van Mil AH, Smith AC, Pouria S, Tarelli E, Brunskill NJ & Eikenboom HCJ (2003), Immunoglobulin A multiple myeloma presenting with Henoch-Schonlein purpura associated with reduced sialylation of IgA1, British Journal of Haematology 122(6).
- Voorzitter van de Wetenschap.Adviesraad vd Landsteiner St. bloedtransfusie research
- Associate Editor van tijdschrift HemaSphere
- Voorzitter
- Horizonscan Geneesmiddelen, werkgroep cardiovasculaire aandoeningen