Hans Vasen
Professor emeritus Prevention of hereditary tumours
- Name
- Prof.dr. H.F.A. Vasen
- h.f.a.vasen@lumc.nl
- ORCID iD
- null
Since 1985, Professor Hans Vasen is staff member of the Department of Gastroenterology & Hepatology of the Leiden University Medical Centre (LUMC) as well as Medical Director of the Dutch Hereditary Cancer Registry. In 2000, Vasen received the Frieda den Hartog Jager Penning (Dutch Association Gastroenterology & Hepatology). In 2017, his study , “Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.” was selected for inclusion in the JCO's report, Clinical Cancer Advances 2017: ASCO’s Annual Report on Progress Against Cancer. The report is an independent annual review of the year’s major achievements and emerging trends in clinical cancer research and care.
More information about Hans Vasen
Since 1985, Professor Hans Vasen is staff member of the Department of Gastroenterology & Hepatology of the Leiden University Medical Centre (LUMC) as well as Medical Director of the Dutch Hereditary Cancer Registry. In 2000, Vasen received the Frieda den Hartog Jager Penning (Dutch Association Gastroenterology & Hepatology). In 2017, his study , “Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.” was selected for inclusion in the JCO's report, Clinical Cancer Advances 2017: ASCO’s Annual Report on Progress Against Cancer. The report is an independent annual review of the year’s major achievements and emerging trends in clinical cancer research and care.
Prevention of Hereditary Cancer
In 2009, he was appointed professor of `Prevention of Hereditary Cancer" at the University of Leiden. The research of professor Vasen focuses mainly on three hereditary cancer syndromes, i.e., Lynch syndrome, familial polyposis and hereditary pancreatic cancer. Part of the research is conducted in collaboration with the Dutch Hereditary Cancer Registry (Stichting Opsporing Erfelijke Tumoren (StOET)).
Academic career
After completion of his training as internist In 1985, he was appointed as Medical Director of the Hereditary Cancer Registry and stafmember at the Department of Gastroenterology & Hepatology of the Leiden University Medical Centre and the Department of Endocrinology of the University Medical Centre Utrecht. In a few years, he succeeded to develop the Dutch Hereditary cancer Registry, one of the first and largest registries worldwide. In 1989, he completed his thesis "Screening for Hereditary Cancer" (University of Utrecht). Since 2014, he is a certified endoscopist of the Dutch Poplation Screening program.
Prizes and honourable appointments
Since 2000 he is one of the Editors-in-Chief of Familial Cancer (Springer publishers).
Professor emeritus Prevention of hereditary tumours
- Faculteit Geneeskunde
- Divisie 2
- Maag-, Darm- en Leverziekten
- Bogdanski, A.M.; Onnekink, A.M.; Inderson, A.; Boekestijn, B.; Bonsing, B.A.; Vasen, H.F.A.; Hooft, J.E. van; Boonstra, J.J.; Mieog, J.S.D.; Wasser, M.N.J.M.; Feshtali, S.; Potjer, T.P.; Klatte, D.C.F. & Leerdam, M.E. van (2024), The added value of blood glucose monitoring in high-risk individuals undergoing pancreatic cancer surveillance, Pancreas 53(7): e566-e572.
- Boekestijn, B.; Feshtali, S.; Vasen, H.; Leerdam, M.E. van; Bonsing, B.A.; Mieog, J.S.D. & Wasser, M.N. (2024), Screening for pancreatic cancer in high-risk individuals using MRI: optimization of scan techniques to detect small lesions, Familial Cancer 23(3): 295-308.
- Klatte, D.C.F.; Boekestijn, B.; Onnekink, A.M.; Dekker, F.W.; Geest, L.G. van der; Wasser, M.N.J.M.; Feshtali, S.; Luelmo, S.A.C.; Morreau, H.; Potjer, T.P.; Inderson, A.; Boonstra, J.J.; Vasen, H.F.A.; Hooft, J.E. van; Bonsing, B.A.; Leerdam, M.E. van & Dutch Pancreatic Canc Grp (2023), Surveillance for pancreatic cancer in high-risk individuals leads to improved outcomes, Gastroenterology 164(7).
- Ibrahim, I.S.; Vasen, H.F.A.; Wasser, M.N.J.M.; Feshtali, S.; Bonsing, B.A.; Morreau, H.; Inderson, A.; Cappel, W.H.D.T.N. & Hout, W.B. van den (2023), Cost-effectiveness of pancreas surveillance, United European Gastroenterology Journal 11(2).
- Klatte, D.C.F.; Boekestijn, B.; Onnekink, A.M.; Dekker, F.W.; Geest, L.G. van der; Wasser, M.N.J.M.M.; Feshtali, S.; Mieog, J.S.D.; Morreau, H.; Potjer, T.P.; Inderson, A.; Boonstra, J.J.; Vasen, H.F.A.; Luelmo, S.; Hooft, J.E. van; Bonsing, B.A. & Leerdam, M.E. van (2023), Comparison of pancreatic cancer outcomes diagnosed in surveillance and the general population: A propensity score-matched analysis., Journal of Clinical Oncology 41: 690-690.
- Klatte, D.C.; Boekestijn, B.; Onnekink, A.; Dekker, F.; Geest, L. van der; Wasser, M.; Feshtali, S.S.; Mieog, J.S.; Luelmo, S.; Morreau, H.; Potjer, T.; Inderson, A.; Boonstra, J.; Vasen, H.; Hooft, J.E. van; Bonsing, B.A. & Leerdam, M. van (2023), SURVEILLANCE FOR PANCREATIC CANCER IN HIGH-RISK INDIVIDUALS LEADS TO IMPROVED OUTCOMES: A PROPENSITY SCORE-MATCHED ANALYSIS, Gastroenterology 164(6): S770-S770.
- Bogdanski, A.; Klatte, D.C.; Onnekink, A.; Boekestijn, B.; Wasser, M.; Feshtali, S.S.; Bonsing, B.A.; Mieog, J.S.; Hooft, J.E. van & Leerdam, M. van (2023), THE ADDED VALUE OF BLOOD GLUCOSE MONITORING IN HIGH-RISK INDIVIDUALS UNDERGOING PANCREATIC CANCER SURVEILLANCE., Gastroenterology 164(6): S598-S598.
- Levink, I.J.M.; Klatte, D.C.F.; Hanna-Sawires, R.G.; Vreeker, G.C.M.; Ibrahim, I.S.; Burgt, Y.E.M. van der; Overbeek, K.A.; Koopmann, B.D.M.; Cahen, D.L.; Fuhler, G.M.; Wuhrer, M.; Bonsing, B.A.; Tollenaar, R.A.E.M.; Vleggaar, F.P.; Vasen, H.F.A.; Leerdam, M.E. van; Bruno, M.J. & Mesker, W.E. (2022), Longitudinal changes of serum protein N-Glycan levels for earlier detection of pancreatic cancer in high-risk individuals, Pancreatology 22(4): 497-506.
- Leicher, L.W.; Huisman, J.F.; Grevenstein, W.M.U. van; Didden, P.; Backes, Y.; Offerhaus, G.J.A.; Lacle, M.M.; Moll, F.C.P.; Geesing, J.M.J.; Smakman, N.; Droste, J.S.T.S.; Verdaasdonk, E.G.G.; Borg, F. ter; Talsma, A.K.; Erkelens, G.W.; Zaag, E.S. van der; Schrauwen, R.W.M.; Wely, B.J. van; Schot, I.; Vermaas, M.; Bergeijk, J.D. van; Sietses, C.; Hazen, W.L.; Wasowicz, D.K.; Ramsoekh, D.; Tuynman, J.B.; Alderlieste, Y.A.; Renger, R.J.; Oort, F.A.; Bilgen, E.J.S.; Vleggaar, F.P.; Vasen, H.F.A.; Cappel, W.H.D.T.N.; Moons, L.M.G. & Westreenen, H.L. van (2022), Colonoscopic-assisted laparoscopic wedge resection for colonic lesions A Prospective Multicenter Cohort Study (LIMERIC-Study), Annals of Surgery 275(5): 933-939.
- Ghorbanoghli, Z.; Kouwen, M. van; Versluys, B.; Bonnet, D.; Devalck, C.; Tinat, J.; Januszkiewicz-Lewandowska, D.; Costas, C.C.; Cottereau, E.; Hardwick, J.C.H.; Wimmer, K.; Brugieres, L.; Colas, C. & Vasen, H.F.A. (2022), High yield of surveillance in patients diagnosed with constitutional mismatch repair deficiency, Journal of Medical Genetics.
- Klatte, D.C.F.; Boekestijn, B.; Wasser, M.N.J.M.; Shahbazi, S.F.; Ibrahim, I.S.; Mieog, J.S.D.; Luelmo, S.A.C.; Morreau, H.; Potjer, T.P.; Inderson, A.; Boonstra, J.J.; Dekker, F.W.; Vasen, H.F.A.; Hooft, J.E. van; Bonsing, B.A. & Leerdam, M.E. van (2022), Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up, Journal of Clinical Oncology 40(28): 3267-+.
- Klatte, D.; Boekestijn, B.; Wasser, M.; Feshtali, S.S.; Ibrahim, I.; Mieog, J.S.; Luelmo, S.; Morreau, H.; Potjer, T.; Inderson, A.; Boonstra, J.; Dekker, F.; Vasen, H.F.; Hooft, J.E. van; Bonsing, B.A. & Leerdam, M. van (2022), PANCREATIC CANCER SURVEILLANCE IN CDKN2A MUTATION CARRIERS: YIELD AND OUTCOMES OF 20 YEARS PROSPECTIVE FOLLOW-UP, Gastroenterology 162(7): S51-S51.
- Vasen, H.F.A. (2022), Progress Report: New insights into the prevention of CRC by colonoscopic surveillance in Lynch syndrome, Familial Cancer 21(1): 49-56.
- Vasen, H.F.A. (2021), Progress Report, Familial Cancer 21.
- Dominguez-Valentin, M.; Plazzer, J.P.; Sampson, J.R.; Engel, C.; Aretz, S.; Jenkins, M.A.; Sunde, L.; Bernstein, I.; Capella, G.; Balaguer, F.; Macrae, F.; Winship, I.M.; Thomas, H.; Evans, D.G.; Burn, J.; Greenblatt, M.; Cappel, W.H.D.T.N.; Sijmons, R.H.; Nielsen, M.; Bertario, L.; Bonanni, B.; Tibiletti, M.G.; Cavestro, G.M.; Lindblom, A.; Valle, A. della; Lopez-Kostner, F.; Alvarez, K.; Gluck, N.; Katz, L.; Heinimann, K.; Vaccaro, C.A.; Nakken, S.; Hovig, E.; Green, K.; Lalloo, F.; Hill, J.; Vasen, H.F.A.; Perne, C.; Buttner, R.; Gorgens, H.; Holinski-Feder, E.; Morak, M.; Holzapfel, S.; Huneburg, R.; Doeberitz, M.V.; Loeffler, M.; Rahner, N.; Weitz, J.; Steinke-Lange, V.; Schmiegel, W.; Vangala, D.; Crosbie, E.J.; Pineda, M.; Navarro, M.; Brunet, J.; Moreira, L.; Sanchez, A.; Serra-Burriel, M.; Mints, M.; Kariv, R.; Rosner, G.; Pinero, T.A.; Pavicic, W.H.; Kalfayan, P.; Broeke, S.W. ten; Mecklin, J.P.; Pylvanainen, K.; Renkonen-Sinisalo, L.; Lepisto, A.; Peltomaki, P.; Hopper, J.L.; Win, A.K.; Buchanan, D.D.; Lindor, N.M.; Gallinger, S.; Marchand, L. le; Newcomb, P.A.; Figueiredo, J.C.; Thibodeau, S.N.; Therkildsen, C.; Hansen, T.V.O.; Lindberg, L.; Rodland, E.A.; Neffa, F.; Esperon, P.; Tjandra, D.; Moslein, G.; Seppala, T.T. & Moller, P. (2021), No difference in penetrance between truncating and missense/aberrant splicing pathogenic variants in MLH1 and MSH2, Journal of Clinical Medicine 10(13).
- Wiik, M.U.; Evans, T.J.; Belhadj, S.; Bolton, K.A.; Dymerska, D.; Jagmohan-Changur, S.; Capella, G.; Kurzawski, G.; Wijnen, J.T.; Valle, L.; Vasen, H.F.A.; Lubinski, J.; Scott, R.J. & Talseth-Palmer, B.A. (2021), A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants, Scientific Reports 11(1).
- Thomas, L.E.; Hurley, J.J.; Sanchez, A.A.; Aznarez, M.R.; Backman, A.S.; Bjork, J.; Capella, G.; Clark, S.K.; Colas, C.; Dekker, E.; Dolwani, S.; Ghorbanoghli, Z.; Gonn, M.; Romero, S.G.; Hes, F.J.; Jundi, H.; Kelland, S.; Latchford, A.R.; Brito, H.L.; Lynch, P.M.; Meuser, E.; Mork, M.E.; Mort, M.; Garcia, M.N.; Nielsen, M.; Parc, Y.; Ricci, M.T.; Saurin, J.C.; Tuin, K. van der; Vasen, H.; Vilar, E.; Vinet, O.; Vitellaro, M.; Walton, S.J.; West, H.D.; Sampson, J.R. & Collaborative Grp Duodenal (2021), Duodenal adenomas and cancer in MUTYH-associated polyposis: an international cohort study, Gastroenterology 160(3): 952-+.
- Overbeek, K.A.; Rodriguez-Girondo, M.D.M.; Wagner, A.; Stoep, N. van der; Akker, P.C. van den; Oosterwijk, J.C.; Os, T.A. van; Kolk, L.E. van der; Vasen, H.F.A.; Hes, F.J.; Cahen, D.L.; Bruno, M.J. & Potjer, T.P. (2021), Genotype-phenotype correlations for pancreatic cancer risk in Dutch melanoma families with pathogenic CDKN2A variants, Journal of Medical Genetics 58(4): 264-269.
- Seppala, T.T.; Dominguez-Valentin, M.; Crosbie, E.J.; Engel, C.; Aretz, S.; Macrae, F.; Winship, I.; Capella, G.; Thomas, H.; Hovig, E.; Nielsen, M.; Sijmons, R.H.; Bertario, L.; Bonanni, B.; Tibiletti, M.G.; Cavestro, G.M.; Mints, M.; Gluck, N.; Katz, L.; Heinimann, K.; Vaccaro, C.A.; Green, K.; Lalloo, F.; Hill, J.; Schmiegel, W.; Vangala, D.; Perne, C.; Strauss, H.G.; Tecklenburg, J.; Holinski-Feder, E.; Steinke-Lange, V.; Mecklin, J.P.; Plazzer, J.P.; Pineda, M.; Navarro, M.; Vida, J.B.; Kariv, R.; Rosner, G.; Pinero, T.A.; Pavicic, W.; Kalfayan, P.; Broeke, S.W. ten; Jenkins, M.A.; Sunde, L.; Bernstein, I.; Burn, J.; Greenblatt, M.; Cappel, W.H.D.T.N.; Valle, A. della; Lopez-Koestner, F.; Alvarez, K.; Buttner, R.; Gorgens, H.; Morak, M.; Holzapfel, S.; Huneburg, R.; Doeberitz, M.V.; Loeffler, M.; Redler, S.; Weitz, J.; Pylvanainen, K.; Renkonen-Sinisalo, L.; Lepisto, A.; Hopper, J.L.; Win, A.K.; Lindor, N.M.; Gallinger, S.; Marchand, L.L.; Newcomb, P.A.; Figueiredo, J.C.; Thibodeau, S.N.; Therkildsen, C.; Wadt, K.A.W.; Mourits, M.J.E.; Ketabi, Z.; Denton, O.G.; Rodland, E.A.; Vasen, H.; Neffa, F.; Esperon, P.; Tjandra, D.; Moslein, G.; Rokkones, E.; Sampson, J.R.; Evans, D.G. & Moller, P. (2021), Uptake of hysterectomy and bilateral salpingooophorectomy in carriers of pathogenic mismatch repair variants, European Journal of Cancer 148: 124-133.
- Hanna-Sawires, R.G.; Schiphuis, J.H.; Wuhrer, M.; Vasen, H.F.A.; Leerdam, M.E. van; Bonsing, B.A.; Mesker, W.E.; Burgt, Y.E.M. van der & Tollenaar, R.A.E.M. (2021), Clinical perspective on proteomic and glycomic biomarkers for diagnosis, prognosis, and prediction of pancreatic cancer, International Journal of Molecular Sciences 22(5).
- Brouwer, J.G.M.; Newcomb, P.A.; Bisseling, T.M.; Figueiredo, J.C.; Hopper, J.L.; Jenkins, M.A.; Koornstra, J.J.; Lindor, N.M.; Vasen, H.F.A.; Win, A.K.; Kampman, E. & Duijnhoven, F.J.B. van (2021), Associations of height with the risks of colorectal and endometrial cancer in persons with Lynch syndrome, American Journal of Epidemiology 190(2): 230-238.
- Ahadova, A.; Seppala, T.T.; Engel, C.; Gallon, R.; Burn, J.; Holinski-Feder, E.; Steinke-Lange, V.; Moslein, G.; Nielsen, M.; Broeke, S.W. ten; Laghi, L.; Dominguez-Valentin, M.; Capella, G.; Macrae, F.; Scott, R.; Huneburg, R.; Nattermann, J.; Hoffmeister, M.; Brenner, H.; Blaker, H.; Doeberitz, M.V.; Sampson, J.R.; Vasen, H.; Mecklin, J.P.; Moller, P. & Kloor, M. (2021), The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance, International Journal of Cancer 148(4): 800-811.
- Daans, C.G.; Ghorbanoghli, Z.; Velthuizen, M.E.; Vasen, H.F.A.; Offerhaus, G.J.A.; Lacle, M.M.; Siersema, P.D.; Ausems, M.G.E.M. & Boonstra, J.J. (2020), Increased prevalence of Barrett's esophagus in patients with MUTYH-associated polyposis (MAP), Familial Cancer 19(2): 183-187.
- Goggins, M.; Overbeek, K.A.; Brand, R.; Syngal, S.; Chiaro, M. del; Bartsch, D.K.; Carrato, A.; Farrell, J.; Fishman, E.K.; Fockens, P.; Gress, T.M.; Hooft, J.E. van; Hruban, R.H.; Kastrinos, F.; Klein, A.; Lennon, A.M.; Lucas, A.; Park, W.; Rustgi, A.; Simeone, D.; Stoffel, E.; Vasen, H.F.A.; Cahen, D.L.; Canto, M.I.; Bruno, M. & Int Canc Pancreas Screening CAPS C (2020), Management of patients with increased risk for familial pancreatic cancer, Gut 69(6).
- Dekkers, N.; Boonstra, J.J.; Moons, L.M.G.; Hompes, R.; Bastiaansen, B.A.; Tuynman, J.B.; Koch, A.D.; Weusten, B.L.A.M.; Pronk, A.; Neijenhuis, P.A.; Westerterp, M.; Hout, W.B. van den; Langers, A.M.J.; Kraan, J. van der; Alkhalaf, A.; Lai, J.Y.L.; Borg, F. ter; Fabry, H.; Halet, E.; Schwartz, M.P.; Nagengast, W.B.; Straathof, J.W.A.; Hove, R.W.R. ten; Oterdoom, L.H.; Hoff, C.; Belt, E.J.T.; Zimmerman, D.D.E.; Hadithi, M.; Morreau, H.; Cuba, E.M.V. de; Leijtens, J.W.A.; Vasen, H.F.A.; Leerdam, M.E. van; Graaf, E.J.R. de; Doornebosch, P.G. & Hardwick, J.C.H. (2020), Transanal minimally invasive surgery (TAMIS) versus endoscopic submucosal dissection (ESD) for resection of non-pedunculated rectal lesions (TRIASSIC study): study protocol of a European multicenter randomised controlled trial, BMC Gastroenterology 20(1).
- Dominguez-Valentin, M.; Sampson, J.R.; Seppala, T.T.; Broeke, S.W. ten; Plazzer, J.P.; Nakken, S.; Engel, C.; Aretz, S.; Jenkins, M.A.; Sunde, L.; Bernstein, I.; Capella, G.; Balaguer, F.; Thomas, H.; Evans, D.G.; Burn, J.; Greenblatt, M.; Hovig, E.; Cappel, W.H.D.T.N.C.; Sijmons, R.H.; Bertario, L.; Tibiletti, M.G.; Cavestro, G.M.; Lindblom, A.; Valle, A. della; Lopez-Kostner, F.; Gluck, N.; Katz, L.H.; Heinimann, K.; Vaccaro, C.A.; Buttner, R.; Gorgens, H.; Holinski-Feder, E.; Morak, M.; Holzapfel, S.; Huneburg, R.; Doeberitz, M.V.; Loeffler, M.; Rahner, N.; Schackert, H.K.; Steinke-Lange, V.; Schmiegel, W.; Vangala, D.; Pylvanainen, K.; Renkonen-Sinisalo, L.; Hopper, J.L.; Win, A.K.; Haile, R.W.; Lindor, N.M.; Gallinger, S.; Marchand, L. le; Newcomb, P.A.; Figueiredo, J.C.; Thibodeau, S.N.; Wadt, K.; Therkildsen, C.; Okkels, H.; Ketabi, Z.; Moreira, L.; Sanchez, A.; Serra-Burriel, M.; Pineda, M.; Navarro, M.; Blanco, I.; Green, K.; Lalloo, F.; Crosbie, E.J.; Hill, J.; Denton, O.G.; Frayling, I.M.; Rodland, E.A.; Vasen, H.; Mints, M.; Neffa, F.; Esperon, P.; Alvarez, K.; Kariv, R.; Rosner, G.; Pinero, T.A.; Gonzalez, M.L.; Kalfayan, P.; Tjandra, D.; Winship, I.M.; Macrae, F.; Moslein, G.; Mecklin, J.P.; Nielsen, M. & Moller, P. (2020), Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants, Genetics in Medicine 22(1): 15-25.
- Terlouw, D.; Suerink, M.; Singh, S.S.; Gille, H.J.J.P.; Hes, F.J.; Langers, A.M.J.; Morreau, H.; Vasen, H.F.A.; Vos, Y.J.; Wezel, T. van; Tops, C.M.; Broeke, S.W. ten & Nielsen, M. (2020), Declining detection rates for APC and biallelic MUTYH variants in polyposis patients, implications for DNA testing policy, European Journal of Human Genetics 28(2): 222-230.
- Blatter, R.; Tschupp, B.; Aretz, S.; Bernstein, I.; Colas, C.; Evans, D.G.; Genuardi, M.; Hes, F.J.; Huneburg, R.; Jarvinen, H.; Lalloo, F.; Moeslein, G.; Renkonen-Sinisalo, L.; Resta, N.; Spier, I.; Varvara, D.; Vasen, H.; Latchford, A.R. & Heinimann, K. (2020), Disease expression in juvenile polyposis syndrome, Genetics in Medicine 22(9): 1524-1532.
- Vermeer, N.C.A.; Valk, M.J.M. van der; Snijders, H.S.; Vasen, H.F.A.; Hoop, A.G. van der; Guicherit, O.R.; Liefers, G.J.; Velde, C.J.H. van de; Stiggelbout, A.M. & Peeters, K.C.M.J. (2020), Psychological distress and quality of life following positive fecal occult blood testing in colorectal cancer screening, Psycho-Oncology 29(6).
- Engel, C.; Ahadova, A.; Seppala, T.T.; Aretz, S.; Bigirwamungu-Bargeman, M.; Blaker, H.; Bucksch, K.; Buttner, R.; Cappel, W.T.D.T.; Endris, V.; Holinski-Feder, E.; Holzapfel, S.; Huneburg, R.; Jacobs, M.A.J.M.; Koornstra, J.J.; Langers, A.M.; Lepisto, A.; Morak, M.; Moslein, G.; Peltomaki, P.; Pylvanainen, K.; Rahner, N.; Renkonen-Sinisalo, L.; Schulmann, K.; Steinke-Lange, V.; Stenzinger, A.; Strassburg, C.P.; Meeberg, P.C. van de; Kouwen, M. van; Leerdam, M. van; Vangala, D.B.; Vecht, J.; Verhulst, M.L.; Doeberitz, M.V.; Weitz, J.; Zachariae, S.; Loeffler, M.; Mecklin, J.P.; Kloor, M.; Vasen, H.F.; German HNPCC Consortium; Dutch Lynch Syndrome Collaborative & Finnish Lynch Syndrome Registry (2020), Associations of pathogenic variants in MLH1, MSH2, and MSH6 with risk of colorectal adenomas and tumors and with somatic mutations in patients with Lynch syndrome, Gastroenterology 158(5): 1326-1333.
- Daans, C.G.; Ghorbanoghli, Z.; Velthuizen, M.E.; Vasen, H.F.A.; Offerhaus, G.J.A.; Lacle, M.M.; Siersema, P.D.; Ausems, M.G.E.M. & Boonstra, J.J. (2020), Increased prevalence of Barrett's esophagus in patients with MUTYH-associated polyposis (MAP), Familial Cancer 19.
- Suerink, M.; Wimmer, K.; Brugieres, L.; Colas, C.; Gallon, R.; Ripperger, T.; Benusiglio, P.R.; Bleiker, E.M.A.; Ghorbanoghli, Z.; Goldberg, Y.; Hardwick, J.C.H.; Kloor, M.; Mentec, M. le; Muleris, M.; Pineda, M.; Ruiz-Ponte, C. & Vasen, H.F.A. (2020), Report of the fifth meeting of the European Consortium 'Care for CMMRD' (C4CMMRD), Leiden, The Netherlands, July 6th 2019, Familial Cancer 20.
- Dominguez-Valentin, M.; Crosbie, E.J.; Engel, C.; Aretz, S.; Macrae, F.; Winship, I.; Capella, G.; Thomas, H.; Nakken, S.; Hovig, E.; Nielsen, M.; Sijmons, R.H.; Bertario, L.; Bonanni, B.; Tibiletti, M.G.; Cavestro, G.M.; Mints, M.; Gluck, N.; Katz, L.; Heinimann, K.; Vaccaro, C.A.; Green, K.; Lalloo, F.; Hill, J.; Schmiegel, W.; Vangala, D.; Perne, C.; Strauss, H.G.; Tecklenburg, J.; Holinski-Feder, E.; Steinke-Lange, V.; Mecklin, J.P.; Plazzer, J.P.; Pineda, M.; Navarro, M.; Vidal, J.B.; Kariv, R.; Rosner, G.; Pinero, T.A.; Gonzalez, M.L.; Kalfayan, P.; Ryan, N.; Broeke, S.W. ten; Jenkins, M.A.; Sunde, L.; Bernstein, I.; Burn, J.; Greenblatt, M.; Cappel, W.H.D.T.N.; Valle, A. della; Lopez-Koestner, F.; Alvarez, K.; Buttner, R.; Gorgens, H.; Morak, M.; Holzapfel, S.; Huneburg, R.; Doeberitz, M.V.; Loeffler, M.; Rahner, N.; Weitz, J.; Pylvanainen, K.; Renkonen-Sinisalo, L.; Lepisto, A.; Auranen, A.; Hopper, J.L.; Win, A.K.; Haile, R.W.; Lindor, N.M.; Gallinger, S.; Marchand, L. le; Newcomb, P.A.; Figueiredo, J.C.; Thibodeau, S.N.; Therkildsen, C.; Okkels, H.; Ketabi, Z.; Denton, O.G.; Rodland, E.A.; Vasen, H.; Neffa, F.; Esperon, P.; Tjandra, D.; Moslein, G.; Sampson, J.R.; Evans, D.G.; Seppala, T.T. & Moller, P. (2020), Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants, Genetics in Medicine 23(4).
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- Watson P, Butzow R, Lynch HT, Mecklin JP, Jarvinen HJ, Vasen HFA, Madlensky L, Fidalgo P & Bernstein I (2001), The clinical features of ovarian cancer in hereditary nonpolyposis colorectal cancer, Gynecologic Oncology 82(2).
- Bulow S, Vasen H, Bulow C, Bisgaard ML, Jarvinen H & Bjork J (2001), Ileorectal anastomosis is appropriate for a subset of patients with familial adenomatous polyposis - Reply, Gastroenterology 121(2).
- Bulow S, Vasen H, Bulow C, Bisgaard ML, Jarvinen H & Bjork J (2001), Ileorectal anastomosis in patients with familial adenomatous polyposis - Reply, Gastroenterology 121(2).
- Peelen T, van Vliet M, Bosch A, Bignell G, Vasen HFA, Klijn JGM, Meijers-Heijboer H, Stratton M, van Ommen GJB, Cornelisse CJ & Devilee P (2000), Screening for BRCA2 mutations in 81 Dutch breast-ovarian cancer families.
- Bulow C, Vasen H, Jarvinen H, Bjork J, Bisgaard ML & Bulow S (2000), Ileorectal anastomosis is appropriate for a subset of patients with familial adenomatous polyposis, Gastroenterology 119(6).
- Peelen T, de Leeuw W, van Lent K, Morreau H, van Eijk R, van Vliet M, Wijnen J, Ligtenberg M, Ginjaar HB, Zweemer R, Menko F, Fodde R, van Ommen GJB, Vasen HFA, Cornelisse CJ & Devilee P (2000), Genetic analysis of a breast-ovarian cancer family, with 7 cases of colorectal cancer linked to BRCA1, fails to support a role for BRCA1 in colorectal tumorigenesis, International Journal of Cancer 88(5).
- van Duijvendijk P, Slors JFM, Taat CW, Oosterveld P, Sprangers MAG, Obertop H & Vasen HFA (2000), Quality of life after total colectomy with ileorectal anastomosis or proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis.
- Vasen HFA, Gruis NA, Frants RR, van der Velden PA, Hille ETM & Bergman W (2000), Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).
- Vasen HFA (2000), When should endoscopic screening in familial adenomatous polyposis be started?
- Vasen HFA (2000), Colorectal cancer and family history, Annales Chirurgiae et Gynaecologiae 89(3).
- de Leeuw WJF, Dierssen J, Vasen HFA, Wijnen JT, Kenter GG, Meijers-Heijboer H, Brocker-Vriends A, Stormorken A, Moller P, Menko F, Cornelisse CJ & Morreau H (2000), Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumours from HNPCC patients, Journal of Pathology 192(3).
- Voskuil DW, Kampman E, Van Geloof W, Grubben M, Kok F, Van Muijen G, Nagengast F, Vasen H & van't Veer P (2000), No major difference in K-ras and p53 abnormalities in sporadic and hereditary nonpolyposis colorectal adenomas, Digestive Diseases and Sciences 45(11).
- Sijmons R, Hofstra R, Hollema H, Mensink R, van der Hout A, Hoekstra H, Kleibeuker J, Molenaar W, Wijnen J, Fodde R, Vasen H & Buys C (2000), Inclusion of malignant fibrous histiocytoma in the tumour spectrum associated with hereditary non-polyposis colorectal cancer, Genes, Chromosomes and Cancer 29(4).
- Vasen HFA (2000), Clinical diagnosis and management of hereditary colorectal cancer syndromes, Journal of Clinical Oncology 18(21).
- MIKKELSEN EO, THASTRUP O & CHRISTENSEN SB (1988), EFFECTS OF THAPSIGARGIN IN ISOLATED RAT THORACIC AORTA, Pharmacology and Toxicology -Copenhagen- 62(1): 7-11.
- Lid data monitoring Commissie Internationale Trial FAB
- Scopie - werkzaamheden
- Editor-in-chief Familial Cancer