Daniel Rozen
Associate professor
- Name
- Dr. D.E. Rozen
- Telephone
- +31 71 527 7990
- d.e.rozen@biology.leidenuniv.nl
- ORCID iD
- 0000-0002-7772-0239
My laboratory uses bacteria in laboratory evolution experiments to study the ecology and genetics of adaptation. We currently have three main research themes. The specific topics addressed are the evolution of bacterial transformation and competence, the causes and consequences of within population phenotypic heterogeneity, and the evolution and ecology of bacteriocins. In addition to our bacterial work, we also study the evolution and ecology of insect-bacterial interactions in the burying beetle Nicrophorus vespilloides.
Postdocs
News
-
Four NWO Open Competition grants for Leiden researchers -
Healthy soil for a healthy gut -
Collaborating bacteria sacrifice themselves for the greater good -
Researchers tackle antibiotic-resistant bacteria -
Altruism in bacteria: colonies divide the work -
IBL-research interview: Daniel Rozen -
Discoverer of the Year, Best Dissertation and Education prize 2015 -
New insights into the production of antibiotics by bacteria
Support
Associate professor
- Science
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Hiskisson P.A., Barona-Gómez F. & Rozen D.E. (2024), Phenotypic heterogeneity in Streptomyces colonies, Current Opinion in Microbiology 78: 102448.
- Ongenae V.M.A., Kempff A., Neer V. van, Shomar H., Tesson F., Rozen D.E., Briegel A. & Claessen D. (2023), Genome sequence and characterization of Streptomyces phages Vanseggelen and Verabelle, representing two new species within the genus Camvirus, Scientific Reports 13: 20153.
- Kasteren S.I. van & Rozen D.E. (2023), Using click chemistry to study microbial ecology and evolution, ISME Communications 3: 9.
- Colizzi S.C., Dijk B. van, Merks R.M.H., Rozen D.E. & Vroomans R.M.A. (2023), Evolution of genome fragility enables microbial division of labor, Molecular Systems Biology 19(3): e11353.
- Ongenae V.M.A., Sidi Mabrouk A., Crooijmans M.E., Rozen D.E., Briegel A. & Claessen D. (2022), Reversible bacteriophage resistance by shedding the bacterial cell wall, Open Biology 12(6): 210379.
- Liakopoulos A., Aulin L.B.S., Buffoni M., Fragkiskou E., Hasselt J.G.C. van & Rozen D.E. (2022), Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution, Proceedings of the National Academy of Sciences 119(18): e2121768119.
- Anonymous (2022), Genome sequence and characterization of Streptomyces phage Pablito, representing a new species within the genus Janusvirus [Genoom sequentie en karakterisatie van streptomyces faag pablito, een nieuwe soort in de genus Janusvirus] (translation: Ongenae V.M.A., Azeredo J., Kropinski A.M., Rozen D.E., Briegel A. & Claessen D. ), Scientific Reports 12: 17785.
- Shitut S.S., Shen M., Claushuis B., Derks R.J.E., Giera M., Rozen D.E., Claessen D. & Kros A. (2022), Generating heterokaryotic cells via bacterial cell-cell fusion, Microbiology Spectrum 10(4): e0169322.
- Westhoff S., Kloosterman A., Hoesel S.F.A. van, Wezel G.P. van & Rozen D.E. (2021), Competition sensing alters antibiotic production in streptomyces, mBio 12: e02729.
- Aulin L.B.S., Liakopoulos A., Graaf P.H. van der, Rozen D.E. & Hasselt J.G.C. (2021), Design principles of collateral sensitivity-based dosing strategies, Nature Communications 12: 5691.
- Zhang Z., Du C., De Barsy F., Liem M., Liakopoulos A., Wezel G.P. van, Choi Y.H., Claessen D. & Rozen D.E. (2020), Antibiotic production in Streptomyces is organized by a division of labor through terminal genomic differentiation, Science Advances 6(3): eaay5781.
- Westhoff S., Otto S.B., Swinkels A., Bode B., Wezel G.P. van & Rozen D.E. (2020), Spatial structure increases the benefits of antibiotic production in Streptomyces, Evolution 74(1): 179-187.
- Shitut S., Bergman G.Ö., Kros A., Rozen D.E. & Claessen D. (2020), Use of permanent wall-deficient cells as a system for the discovery of new-to-nature metabolites, Microorganisms 8(12): 1897.
- Westhoff S., Wezel G.P. van & Rozen D.E. (2017), Distance-dependent danger responses in bacteria, Current Opinion in Microbiology 36: 95-101.
- Westhoff S., Leeuwe T.M. van, Qachach O., Zhang Z., Wezel G.P. van & Rozen D.E. (2017), The evolution of no-cost resistance at sub-MIC concentrations of streptomycin in Streptomyces coelicolor, The ISME Journal 11(5): 1168-1178.
- Wang Y. & Rozen D.E. (2017), Gut Microbiota Colonization and Transmission in the Burying Beetle Nicrophorus vespilloides throughout Development, Applied and Environmental Microbiology 83(9): e03250.
- Lugtenberg E.J.J., Rozen D.E. & Kamilova F. (2017), Wars between microbes on roots and fruits, F1000Research 6: 343.
- Zhang Z., Claessen D. & Rozen D.E. (2016), Understanding Microbial Divisions of Labor, Frontiers in Microbiology 7: 2070.
- Rozen D.E. (2015), The dubious motives of generous men, The Journal of Experimental Biology 218(13): 1980.
- Rozen D.E. (2015), A head for sex, The Journal of Experimental Biology 218(19): 2984-2985.
- Abrudan M.I., Smakman F., Gimbergen A., Westhoff S., Miller E.L., Wezel G.P. van & Rozen D.E. (2015), Socially mediated induction and suppression of antibiosis during bacterial coexistence, Proceedings of the National Academy of Sciences 112(35): 11054–11059.
- Wolf J.B., Howie J.A., Parkinson K., Gruenheit N., Melo D., Rozen D.E. & Thompson C.R.L. (2015), Fitness trade-offs result in the illusion of social success, Current Biology 25(8): 1086-1090.
- Rozen D.E. (2015), The invisibility cloak of filefish, The Journal of Experimental Biology 218(7): 966-966.
- Jacobs C.G.C., Wang Y., Vogel H., Vilcinskas A., Zee M. van der & Rozen D.E. (2014), Egg survival is reduced by grave-soil microbes in the carrion beetle, Nicrophorus vespilloides, BMC Evolutionary Biology 14: 208.
- Claessen D., Rozen D.E., Kuipers O.P., Søgaard-Andersen L. & Wezel G.P. van (2014), Bacterial solutions to multicellularity: a tale of biofilms, filaments and fruiting bodies, Nature Reviews Microbiology 12(2): 115-124.
- Arce A.N., Smiseth P.T. & Rozen D.E. (2013), Antimicrobial secretions and social immunity in larval burying beetles, Nicrophorus vespilloides, Animal Behaviour 86 (4): 741-745.
- Rozen D.E. (2013), Parasites and the great divide, The Journal of Experimental Biology 216 (2): vi-vi.
- Rozen D.E. (2013), The electrifying buzz of bees, The Journal of Experimental Biology 216 (12): iv-iv.
- Rozen D.E. (2013), Birds' digestion cleanses passing seeds, The Journal of Experimental Biology 216 (19): v-vi.
- Engelmoer D.J.P., Donaldson I. & Rozen D.E. (2013), Conservative Sex and the Benefits of Transformation in Streptococcus pneumoniae, PLoS Pathogens 9 (11), e10037581: .
- Evans B.A. & Rozen D.E. (2013), Significant variation in transformation frequency in Streptococcus pneumoniae, The ISME Journal 7 (4): 791-799.
- Rozen D.E. (2013), A mother's secret password, The Journal of Experimental Biology 216 (7): v-v.