Cornelis van Kooten
Professor Experimental Nephrology, in particular the immunology of transplantation
- Name
- Prof.dr. C. van Kooten
- Telephone
- +31 71 526 2148
- c.van_kooten@lumc.nl
- ORCID iD
- 0000-0002-6257-0899
Cees van Kooten is professor in experimental nephrology and transplant immunology, head of the immunological research laboratory of the section nephrology of the department of internal medicine and part of the Einthoven laboratory of vascular and regenerative medicine. He is chair of the exam committee master Biomedical Sciences.
Cees van Kooten is professor in experimental nephrology and transplant immunology, head of the immunological research laboratory of the section nephrology of the department of internal medicine and part of the Einthoven laboratory of vascular and regenerative medicine. He is chair of the exam committee master Biomedical Sciences.
Renal transplantation
Renal transplantation is a life saving procedure and strongly increases the quality of life. However, transplanted patients are dependent on a life long treatment with immunosuppressive medication. Renal transplantation results in a strong and unique immune reaction. it is increasingly clear that the process of rejection is complex and includes many arms of the immune system, including innate immunity.
The current challenge in transplantation is to find ways to inhibit the chronic injury of the tissue and at the same time reduce the burden of immunosuppressive medication and make immunosuppression more specific. To reach this final goal, basic, clinical and translational research projects are being exploited. Detailed knowledge on the rejection process and state of the art methods to monitor these immune responses will be instrumental to develop and implement novel therapeutic strategies including immunotherapy and cell therapy. This research at the crossroad of transplantation, immunology and nephrology will be a major contribution to the development of Regenerative Medicine.
Academic career
Cees van Kooten studied biology at the University of Amsterdam with specializations in immunology and molecular biology and graduated in 1987. After a 3 month stay at the Department of Clinical Immunology, University of Gothenburg, Sweden, he started on his doctoral research in Amsterdam in the Department Autoimmune diseases of the CLB (the “blood bank”). In 1992 he successfully defended his dissertation, entitled “The role of cytokines in the activation of human malignant B cells”. Subsequently, he spent two years as a postdoctoral fellow at the renowned immunological research Institute from Schering Plough in Lyon, France. In 1995, he moved as a post-doc to the Department of Nephrology of the LUMC, followed by a fellowship from the Royal Dutch Academy of Science (KNAW) fellowship at the LUMC to investigate the role of CD40-CD40L in the rejection of transplanted kidneys. In 2003 he became associate professor and in 2009 he was appointed as professor in Experimental Nephrology and Transplant Immunology at the Leiden University Medical Center. The title of his inaugural lecture was “TOPsport op gladde bruggen-TOPsports on slippery bridges”.
Cees van Kooten is (co) author of over 250 scientific articles. He has garnered substantial research grants. He has been active in reviewing both for scientific journals as well as for grant organizations, he is a former member of the scientific board of the Dutch Kidney Foundation and former treasurer of the Dutch Society for Immunology (NvvI). Currently he is member of the Immunonephrology Working Group of the European ERA/EDTA.
Cees van Kooten has been (co)-supervisor of more than 20 PhD students and has been active in the teaching program of the LUMC in Medicine and Biomedical Sciences, ranging from bachelor and master student to post-doctoral courses.
Prizes and honourable appointments
Cees van Kooten received a research grant from the Royal Netherlands Academy of Arts and Sciences (KNAW, 1997) and the C.J.Kok award of the University Leiden (1999). He received the Dolph Adams Award 2004 for the best cited review in the J Leukoc Biol and the Anthony P Monaco Award 2014 for the best translational science publication in Transplantation.
More information:
http://www.einthovenlaboratory.com/cees-van-kooten-phd/
Follow Cees van Kooten op:
| LinkedIn | Orcid | ResearchGate | PubMed
Professor Experimental Nephrology, in particular the immunology of transplantation
- Faculteit Geneeskunde
- Divisie 2
- Interne Geneeskunde
- Nierziekten
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Cotic, J.; Osmani, Z.; Bie, F.J. de; Kamerling, S.W.A.; Maurik, A. van; Dimelow, R.; Gregan, Y.I.; Fox, N.L.; Rabelink, T.J.; Roth, D.A.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, Y.K.O. (2024), Disruption of memory B-cell trafficking by belimumab in patients with systemic lupus erythematosus, Rheumatology 63(9): 2387-2398.
- Arends, E.J.; Meziyerh, S.; Moes, D.J.A.R.; Kamerling, S.W.A.; Kooy, S. van der; Ogando, N.S.; Snijder, E.J.; Hemert, M. van; Visser, L.G.; Feltkamp, M.C.W.; Claas, E.C.J.; Rabelink, T.J.; Kooten, C. van; Vries, A.P.J. de & Teng, Y.K.O. (2023), Voclosporin and the antiviral effect against SARS-CoV-2 in immunocompromised kidney patients, Kidney International Reports 8(12): 2654-2664.
- Hilhorst, M.; Bemelman, F.J.; Bruchfeld, A.; Fernandez-Juarez, G.M.; Floege, J.; Frangou, E.; Goumenos, D.; Kooten, C. van; Kronbichler, A.; Stevens, K.I.; Turkmen, K.; Wiersinga, W.J.; Anders, H.J. & Immunonephrol Working Grp European (2023), Prophylactic and early outpatient treatment of COVID-19 in patients with kidney disease, Nephrology Dialysis Transplantation 38(8): 1807-1816.
- Grabowska, J.; Léopold, V.; Olesek, K.; Twilhaar, M.K.N.; Affandi, A.J.; Brouwer, M.C.; Jongerius, I.; Verschoor, A.; Kooten, C. van; Kooyk, Y. van; Storm, G.; Veer, C. van 't & Haan, J.M.M. den (2023), Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses, Frontiers in Immunology 14.
- Hendriks, S.H.; Heidt, S.; Schulz, A.R.; Fijter, J.W. de; Reinders, M.E.J.; Koning, F. & Kooten, C. van (2023), Peripheral blood immune cell composition after autologous MSC infusion in kidney transplantation recipients, Transplant International 36.
- Mulvey, J.F.; Shaheed, S.U.; Charles, P.D.; Snashall, C.; Faro, M.L. lo; Sutton, C.W.; Jochmans, I.; Pirenne, J.; Kooten, C. van; Leuvenink, H.G.D.; Kaisar, M. & Ploeg, R.J. (2023), Perfusate proteomes provide biological insight into oxygenated versus standard hypothermic machine perfusion in kidney transplantation, Annals of Surgery 278(5): 676-682.
- Moura, M.C.; Gauckler, P.; Anders, H.J.; Bruchfeld, A.; Fernandez-Juarez, G.M.; Floege, J.; Frangou, E.; Goumenos, D.; Segelmark, M.; Turkmen, K.; Kooten, C. van; Tesar, V.; Geetha, D.; Fervenza, F.C.; Jayne, D.R.W.; Stevens, K.; Kronbichler, A. & ERA Immunonephrol Working Grp IWG (2023), Management of antineutrophil cytoplasmic antibody-associated vasculitis with glomerulonephritis as proposed by the ACR 2021, EULAR 2022 and KDIGO 2021 guidelines/recommendations, Nephrology Dialysis Transplantation 38(11): 2637-2651.
- Essen, M. van; Schlagwein, N.; Gijlswijk-Janssen, D. van; Teng, O. & Kooten, C. van (2023), Keeping properdin in check: Serum component(s) inhibit(s) the binding of properdin, Immunobiology 228(5): 83-84.
- Dreyer, G.J.; Drabbels, J.J.M.; Fijter, J.W. de; Kooten, C. van; Reinders, M.E.J. & Heidt, S. (2023), Cell-free DNA measurement of three genomes after allogeneic MSC therapy in kidney transplant recipients indicates early cell death of infused MSC, Frontiers in Immunology 14.
- Knijff, L.; Kooij, S. van der; Gijlswijk-Janssen, D. van; Essen, M. van; Mulvey, J.; Faro, L. lo; Ploeg, R. & Kooten, C. van (2023), Activation of the complement system early on during brain death management, Immunobiology 228(5): 65-65.
- Gaykema, L.H.; Nieuwland, R.Y. van; Dekkers, M.C.; Essen, M.F. van; Heidt, S.; Zaldumbide, A.; Berg, C.W. van den; Rabelink, T.J. & Kooten, C. van (2023), Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids, Frontiers in Immunology 13.
- Knijff, L.W.D.; Kooten, C. van & Ploeg, R.J. (2022), The effect of hypothermic machine perfusion to ameliorate ischemia-reperfusion injury in donor organs, Frontiers in Immunology 13.
- Essen, M.F. van; Schlagwein, N.; Gijlswijk-Janssen, D.J. van; Ruben, J.M.; Kooten, C. van & COMBAT Consortium (2022), Properdin produced by dendritic cells contributes to the activation of T cells, Immunobiology 227(4).
- Alem, C.M.A. van; Bank, J.R.; Vries, D.K. de; Bajema, I.M.; Mallat, M.J.K.; Fijter, J.W. de; Rotmans, J.I. & Kooten, C. van (2022), Presence of CD163+macrophages in DCD kidneys with high DGF reduces the risk for acute cellular rejection in 6 months after kidney transplantation, Transplant Immunology 75.
- Essen, M.F. van; Schlagwein, N.; Hoven, E.M.P. van den; Gijlswijk-Janssen, D.J. van; Lubbers, R.; Bos, R.M. van den; Born, J. van den; Ruben, J.M.; Trouw, L.A.; Kooten, C. van & COMBAT Consortium (2022), Initial properdin binding contributes to alternative pathway activation at the surface of viable and necrotic cells, European Journal of Immunology 52(4).
- Schaik, M. van; Arends, E.J.; Soonawala, D.; Ommen, E. van; Leeuw, K. de; Limper, M.; Paassen, P. van; Huizinga, T.W.J.; Toes, R.E.M.; Kooten, C. van; Rotmans, J.I.; Rabelink, T.J. & Teng, Y.K.O. (2022), Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: , Trials 23(1).
- Stevens, K.I.; Frangou, E.; Shin, J.I.; Anders, H.J.; Bruchfeld, A.; Schonermarck, U.; Hauser, T.; Westman, K.; Fernandez-Juarez, G.M.; Floege, J.; Goumenos, D.; Turkmen, K.; Kooten, C. van; McAdoo, S.P.; Tesar, V.; Segelmark, M.; Geetha, D.; Jayne, D.R.W.; Kronbichler, A.; Immunonephrology Working Grp IWG; European Renal Assoc ERA & European Vasculitis Soc EUVAS (2022), Perspective on COVID-19 vaccination in patients with immune-mediated kidney diseases: consensus statements from the ERA-IWG and EUVAS, Nephrology Dialysis Transplantation 37(8): 1400-1410.
- Duijl, T.T. van; Ruhaak, L.R.; Kooten, C. van; Fijter, J.W. de & Cobbaert, C.M. (2022), Multiplex LC-MS/MS testing for early detection of kidney injury, JOURNAL OF APPLIED LABORATORY MEDICINE 7(4): 923-930.
- Duijl, T.T. van; Ruhaak, L.R.; Kooten, C. van; Fijter, J.W. de & Cobbaert, C.M. (2022), Multiplex LC-MS/MS testing for early detection of kidney injury, JOURNAL OF APPLIED LABORATORY MEDICINE 7(4): 923-930.
- Essen, M. van; Schlagwein, N.; Hoven, E. van den; Gijlswijk-Janssen, D. van; Lubbers, R.; Bos, R. van den; Born, J. van den; Ruben, J.; Trouw, L. & Kooten, C. van (2022), Initial properdin binding contributes to alternative pathway activation on necrotic cells, Molecular Immunology 141: 191-192.
- Wortel, C.; Wetering, R. van de; Dooren, H. van; Stork, E.M.; Bakker, A.M.; Brehler, A.S.; Kissel, T.; Reijm, S.; Stoeken-Rijsbergen, G.; Schie, K. van; Rutgers, A.; Trouw, L.A.; Huizinga, T.; Teng, Y.K.O.; Kooten, C. van; Heeringa, P.; Toes, R. & Scherer, H.U. (2022), EXPANSION OF MYELOPEROXIDASE (MPO)-SPECIFIC IGM B CELLS IN ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA)-ASSOCIATED VASCULITIS, Annals of the Rheumatic Diseases 81: 61-61.
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Cotic, J.; Osmani, Z.; Bie, F. de; Kamerling, S.; Maurik, A. van; Dimelow, R.; Gregan, Y.I.; Fox, N.L.; Rabelink, T.; Roth, D.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, Y.K.O. (2022), BELIMUMAB DISRUPTS MEMORY B-CELL TRAFFICKING IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, Annals of the Rheumatic Diseases 81: 324-325.
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Cotic, J.; Osmani, Z.; Bie, F.J. de; Kamerling, S.W.A.; Maurik, A. van; Dimelow, R.; Gregan, Y.I.; Fox, N.L.; Rabelink, T.J.; Roth, D.A.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, O. (2022), Belimumab Disrupts Memory B-Cell Trafficking in Patients with Systemic Lupus Erythematosus, Arthritis & Rheumatology 74: 3292-3293.
- Jager, N.M.; Venema, L.H.; Arykbaeva, A.S.; Meter-Arkema, A.H.; Ottens, P.J.; Kooten, C. van; Mollnes, T.E.; Alwayn, I.P.J.; Leuvenink, H.G.D.; Pischke, S.E. & PROPER study consortium (2022), Complement Is activated during normothermic machine perfusion of porcine and human discarded kidneys, Frontiers in Immunology 13.
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Osmani, Z.; Bie, F. de; Kamerling, S.W.A.; Rabelink, T.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, Y.K.O. (2022), BELIMUMAB DISRUPTS MEMORY B CELL TRAFFICKING IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, Nephrology Dialysis Transplantation 37: I170-I170.
- Renner, B.; Laskowski, J.; Poppelaars, F.; Ferreira, V.P.; Blaine, J.; Antonioli, A.H.; Hannan, J.P.; Kovacs, J.M.; Kooten, C. van; You, Z.Y.; Pickering, M.C.; Holers, V.M. & Thurman, J.M. (2022), Factor H related proteins modulate complement activation on kidney cells, Kidney International 102(6): 1331-1344.
- Aanhold, C.C.L. van; Koudijs, A.; Dijkstra, K.L.; Wolterbeek, R.; Bruijn, J.A.; Kooten, C. van & Baelde, H.J. (2022), The VEGF inhibitor soluble Fms-like tyrosine kinase 1 does not promote AKI-to-CKD transition, International Journal of Molecular Sciences 23(17).
- Eerhart, M.J.; Reyes, J.A.; Blanton, C.L.; Danobeitia, J.S.; Chlebeck, P.J.; Zitur, L.J.; Springer, M.; Polyak, E.; Coonen, J.; Capuano, S.; D'Alessandro, A.M.; Torrealba, J.; Amersfoort, E. van; Ponstein, Y.; Kooten, C. van; Burlingham, W.; Sullivan, J.; Pozniak, M.; Zhong, W.X.; Yankol, Y. & Fernandez, L.A. (2022), Complement blockade in recipients prevents delayed graft function and delays antibody-mediated rejection in a nonhuman primate model of kidney transplantation, Transplantation 106(1): 60-71.
- Seidel, F.; Kleemann, R.; Duyvenvoorde, W. van; Trigt, N. van; Keijzer, N.; Kooij, S. van der; Kooten, C. van; Verschuren, L.; Menke, A.; Kiliaan, A.J.; Winter, J.; Hughes, T.R.; Morgan, B.P.; Baas, F.; Fluiter, K. & Morrison, M.C. (2022), Therapeutic intervention with anti-complement component 5 antibody does not reduce NASH but does attenuate atherosclerosis and MIF concentrations in Ldlr-/-.Leiden mice, International Journal of Molecular Sciences 23(18).
- Seidel, F.; Kleemann, R.; Duyvenvoorde, W. van; Keijzer, N.; Trigt, N. van; Kooij, S. van der; Kooten, C. van; Verschuren, L.; Menke, A.L.; Kiliaan, A.; Winter, J.; Hughes, T.; Morgan, P.; Baas, F.; Fluiter, K. & Morrison, M. (2022), THERAPEUTIC INHIBITION OF COMPLEMENT COMPONENT 5 DOES NOT REDUCE NASH PROGRESSION BUT DOES ATTENUATE ATHEROSCLEROSIS DEVELOPMENT IN LDLR--/--.LEIDEN MICE, Hepatology 76: S690-S691.
- Seidel, F.; Kleemann, R.; Duyvenvoorde, W. van; Trigt, N. van; Keijzer, N.; Kooij, S. van der; Kooten, C. van; Verschuren, L.; Menke, A.L.; Winter, J.; Hughes, T.; Morgan, P.; Baas, F.; Fluiter, K.; Morrison, M.C. & Kiliaan, A. (2022), Therapeutic inhibition of complement component 5 does not reduce NASH progression but does attenuate atherosclerosis development in Ldlr-/-.Leiden mice, Journal of Hepatology 77: S698-S698.
- Caravaca-Fontan, F.; Fernandez-Juarez, G.M.; Floege, J.; Goumenos, D.; Kronbichler, A.; Turkmen, K.; Kooten, C. van; Frangou, E.; Stevens, K.I.; Segelmark, M.; Tesar, V.; Anders, H.J.; Bruchfeld, A.; Immunonephrology Working Grp & European Renal Assoc (2022), The management of membranous nephropathy, Nephrology Dialysis Transplantation 37(6): 1033-1042.
- Dirikgil, E.; Leeuwen, J.R. van; Bredewold, O.W.; Ray, A.; Jonker, J.T.; Soonawala, D.; Remmelts, H.H.F.; Dam, B. van; Bos, W.J.; Kooten, C. van; Rotmans, J.; Rabelink, T. & Teng, Y.K.O. (2022), ExploriNg DUrable Remission with Rituximab in ANCA-associatEd vasculitis (ENDURRANCE trial), BMJ Open 12(9).
- Dam, L.S. van; Dirikgil, E.; Bredewold, E.W.; Ray, A.; Bakker, J.A.; Kooten, C. van; Rabelink, T.J. & Teng, Y.K.O. (2021), PR3-ANCAs predict relapses in ANCA-associated vasculitis patients after rituximab, Nephrology Dialysis Transplantation 36(8): 1408-1417.
- Kronbichler, A.; Anders, H.J.; Fernandez-Juarez, G.M.; Floege, J.; Goumenos, D.; Segelmark, M.; Tesar, V.; Turkmen, K.; Kooten, C. van; Bruchfeld, A. & Immunonephrology Working Grp ERA-E (2021), Recommendations for the use of COVID-19 vaccines in patients with immune-mediated kidney diseases, Nephrology Dialysis Transplantation 36(7): 1160-1168.
- Kroon, J.; Viho, E.M.G.; Gentenaar, M.; Koorneef, L.L.; Kooten, C. van; Rensen, P.C.N.; Kooijman, S.; Hunt, H. & Meijer, O.C. (2021), The development of novel glucocorticoid receptor antagonists, Pharmacological Research 168.
- Groeneweg, K.E.; Toorn, F.A. van der; Roelen, D.L.; Kooten, C. van; Heidt, S.; Claas, F.H.J.; Reinders, M.E.J.; Fijter, J.W. de & Soonawala, D. (2021), Single antigen testing to reduce early antibody-mediated rejection risk in female recipients of a spousal donor kidney., Transplant Immunology.
- Alem, C.M.A. van; Metselaar, J.M.; Kooten, C. van & Rotmans, J.I. (2021), Recent advances in liposomal-based anti-inflammatory therapy, Pharmaceutics 13(7).
- Divella, C.; Stasi, A.; Franzin, R.; Rossini, M.; Pontrelli, P.; Sallustio, F.; Netti, G.S.; Ranieri, E.; Lacitignola, L.; Staffieri, F.; Crovace, A.M.; Lucarelli, G.; Ditonno, P.; Battaglia, M.; Daha, M.R.; Pol, P. van der; Kooten, C. van; Grandaliano, G.; Gesualdo, L.; Stallone, G. & Castellano, G. (2021), Pentraxin-3-mediated complement activation in a swine model of renal ischemia/reperfusion injury, Aging 13(8): 10920-10933.
- Teng, Y.K.O.; Pusey, C.D.; Vaglio, A.; Mok, C.C. & Kooten, C. van (2021), Editorial: immune monitoring responses in renal autoimmune diseases, Frontiers in Immunology 12.
- Koopman, J.J.E.; Essen, M.F. van; Rennke, H.G.; Vries, A.P.J. de & Kooten, C. van (2021), Deposition of the membrane attack complex in healthy and diseased human kidneys, Frontiers in Immunology 11.
- Reinders, M.E.J.; Groeneweg, K.E.; Hendriks, S.H.; Bank, J.R.; Dreyer, G.J.; Vries, A.P.J. de; Pel, M. van; Roelofs, H.; Huurman, V.A.L.; Meij, P.; Moes, D.J.A.R.; Fibbe, W.E.; Claas, F.H.J.; Roelen, D.L.; Kooten, C. van; Kers, J.; Heidt, S.; Rabelink, T.J. & Fijter, J.W. de (2021), Autologous bone marrow-derived mesenchymal stromal cell therapy with early tacrolimus withdrawal, American Journal of Transplantation 21(9).
- Witjas, F.; Wang, G.; Graaf, A. de; Kostidis, S.; Avramut, C.; Haan, M. de; Alwayn, I.; Kers, J.; Kooten, C. van; Heijs, B.; Engelse, M. & Rabelink, T. (2021), METABOLISM-REGULATED SUB-NORMOTHERMIC CULTURE SYSTEM OF HUMAN KIDNEYS RETAINS EX VIVO VIABILITY FOR 4 DAYS, Transplant International 34: 64-64.
- Kraaij, T.; Arends, E.J.; Dam, L.S. van; Kamerling, S.W.A.; Daele, P.L.A. van; Bredewold, O.W.; Ray, A.; Bakker, J.A.; Scherer, H.U.; Huizinga, T.J.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2021), Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus, Nephrology Dialysis Transplantation 36(8): 1474-1483.
- Stang, M.B. le; Gleeson, P.J.; Daha, M.R.; Monteiro, R.C. & Kooten, C. van (2021), Is complement the main accomplice in IgA nephropathy? From initial observations to potential complement-targeted therapies, Molecular Immunology 140: 1-11.
- Teng, Y.K.O.; Dam, L. van; Oskam, J.; Kamerling, S.W.A.; Arends, E.J.; Bredewold, E.; Dongen, J.J.M. van; Rabelink, T.J. & Kooten, C. van (2021), HIGHLY SENSITIVE FLOW CYTOMETRIC DETECTION OF RESIDUAL B-CELLS AFTER RITUXIMAB IN ANTINEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIS PATIENTS, Nephrology Dialysis Transplantation 36.
- Bovenkamp, F.S. van de; Dijkstra, D.J.; Kooten, C. van; Gelderman, K.A. & Trouw, L.A. (2021), Circulating C1q levels in health and disease, more than just a biomarker, Molecular Immunology 140: 206-216.
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Osmani, Z.; Kamerling, S.W.A.; Rabelink, T.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, Y.K.O. (2021), BELIMUMAB ADD-ON THERAPY MOBILIZES MEMORY B CELLS INTO CIRCULATION OF SLE PATIENTS, Nephrology Dialysis Transplantation 36.
- Arends, E.J.; Zlei, M.; Tipton, C.M.; Osmani, Z.; Kamerling, S.; Rabelink, T.; Sanz, I.; Dongen, J.J.M. van; Kooten, C. van & Teng, Y.K.O. (2021), BELIMUMAB ADD-ON THERAPY MOBILISES MEMORY B CELLS INTO THE CIRCULATION OF PATIENTS WITH SLE, Annals of the Rheumatic Diseases 80: 585-585.
- Anders, H.J.; Loutan, J.; Bruchfeld, A.; Fernandez-Juarez, G.M.; Floege, J.; Goumenos, D.; Turkmen, K.; Kooten, C. van; Frangou, E.; Stevens, K.I.; Kronbichler, A.; Segelmark, M.; Tesar, V.; Immunonephrology Working Grp & European Renal Assoc (2021), The management of lupus nephritis as proposed by EULAR/ERA 2019 versus KDIGO 2021, Nephrology Dialysis Transplantation 38(3).
- Sier, V.Q.; Vries, M.R. de; Vorst, J.R. van der; Vahrmeijer, A.L.; Kooten, C. van; Cruz, L.J.; Geus-Oei, L.F. de; Ferreira, V.; Sier, C.F.M.; Alves, F. & Muthana, M. (2021), Cell-based tracers as Trojan horses for image-guided surgery, International Journal of Molecular Sciences 22(2).
- Dam, L.S. van; Oskam, J.M.; Kamerling, S.W.A.; Arends, E.J.; Bredewold, O.W.; Berkowska, M.A.; Dongen, J.J.M. van; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2020), Highly sensitive flow cytometric detection of residual B-cells after rituximab in anti-neutrophil cytoplasmic antibodies-associated vasculitis patients, Frontiers in Immunology 11.
- Car, H.; Karahan, G.E.; Dreyer, G.J.; Brand-Schaaf, S.H.; Vries, A.P.J. de; Kooten, C. van; Kramer, C.S.M.; Roelen, D.L.; Claas, F.H.J. & Heidt, S. (2020), Low incidence of IgA isotype of HLA antibodies in alloantigen exposed individuals, HLA: Immune Response Genetics 97(2).
- Kraaij, T.; Arends, E.J.; Dam, L.S. van; Kamerling, S.W.A.; Daele, P.L.A. van; Bredewold, O.W.; Ray, A.; Bakker, J.A.; Scherer, H.U.; Huizinga, T.J.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2020), Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus: 2-year results, Nephrology Dialysis Transplantation 36(8).
- Dam, L.S. van; Dirikgil, E.; Bredewold, E.W.; Ray, A.; Bakker, J.A.; Kooten, C. van; Rabelink, T.J. & Teng, Y.K.O. (2020), Proteinase-3-anti-neutrophil cytoplasmic antibodies (PR3-ANCAs) predict relapses in ANCA-associated vasculitis patients after rituximab, Nephrology Dialysis Transplantation 36(8).
- Groeneweg, K.E.; Au, Y.W.; Duijs, J.M.G.J.; Florijn, B.W.; Kooten, C. van; Fijter, J.W. de; Reinders, M.E.J.; Zonneveld, A.J. van & Bijkerk, R. (2020), Diabetic nephropathy alters circulating long noncoding RNA levels that normalize following simultaneous pancreas-kidney transplantation, American Journal of Transplantation 20(12).
- Danobeitia, J.S.; Zens, T.J.; Chlebeck, P.J.; Zitur, L.J.; Reyes, J.A.; Eerhart, M.J.; Coonen, J.; Capuano, S.; D'Alessandro, A.M.; Torrealba, J.R.; Burguete, D.; Brunner, K.; Amersfoort, E. van; Ponstein, Y.; Kooten, C. van; Jankowska-Gan, E.; Burlingham, W.; Sullivan, J.; Djamali, A.; Pozniak, M.; Yankol, Y. & Fernandez, L.A. (2020), Targeted donor complement blockade after brain death prevents delayed graft function in a nonhuman primate model of kidney transplantation, American Journal of Transplantation 20(6): 1513-1526.
- Alem, C.M.A. van; Schmidbauer, M.; Rong, S.; Derlin, K.; Schmitz, J.; Brasen, J.H.; Thorenz, A.; Chen, R.J.; Ruben, J.M.; Winter, E.M.; Schilperoort, M.; Kooijman, S.; Lalai, R.A.; Metselaar, J.M.; Klemann, C.; Meier, M.; Kooten, C. van; Gueler, F. & Rotmans, J.I. (2020), Liposomal delivery improves the efficacy of prednisolone to attenuate renal inflammation in a mouse model of acute renal allograft rejection, Transplantation 104(4): 744-753.
- Dam, L.S. van; Osmani, Z.; Kamerling, S.W.A.; Kraaij, T.; Bakker, J.A.; Scherer, H.U.; Rabelink, T.J.; Voll, R.E.; Alexander, T.; Isenberg, D.A.; Kooten, C. van & Teng, Y.K.O. (2020), A reverse translational study on the effect of rituximab, rituximab plus belimumab, or bortezomib on the humoral autoimmune response in SLE, Rheumatology 59(10): 2734-2745.
- Groeneweg, K.E.; Duijs, J.M.G.J.; Florijn, B.W.; Kooten, C. van; Fijter, J.W. de; Zonneveld, A.J. van; Reinders, M.E.J. & Bijkerk, R. (2020), Circulating long noncoding RNA LNC-EPHA6 associates with acute rejection after kidney transplantation, International Journal of Molecular Sciences 21(16).
- Pontrelli, P.; Grandaliano, G. & Kooten, C. van (2020), Editorial: kidney transplantation and innate immunity, Frontiers in Immunology 11.
- Craenmehr, M.H.C.; Keur, C. van der; Anholts, J.D.H.; Kapsenberg, J.M.; Westerlaken, L.A. van der; Kooten, C. van; Claas, F.H.J.; Heidt, S. & Eikmans, M. (2020), Effect of seminal plasma on dendritic cell differentiation in vitro depends on the serum source in the culture medium, Journal of Reproductive Immunology 137.
- Bovee, D.M.; Roksnoer, L.C.W.; Kooten, C. van; Rotmans, J.I.; Vogt, L.; Borst, M.H. de; Zietse, R.; Danser, A.H.J. & Hoorn, E.J. (2020), Effect of sodium bicarbonate supplementation on the renin-angiotensin system in patients with chronic kidney disease and acidosis, Journal of Nephrology 34.
- Anders, H.J.; Bruchfeld, A.; Juarez, G.M.F.; Floege, J.; Goumenos, D.; Turkmen, K.; Kooten, C. van; Tesar, V.; Segelmark, M. & Immunonephrology Working Grp ERA-E (2020), Recommendations for the management of patients with immune-mediated kidney disease during the severe acute respiratory syndrome coronavirus 2 pandemic, Nephrology Dialysis Transplantation 35(6): 920-925.
- Essen, M.F. van; Schlagwein, N.; Gijlswijk-Janssen, D.J. van; Anholts, J.D.H.; Eikmans, M.; Ruben, J.M.; Kooten, C. van & COMBAT Consortium (2020), Culture medium used during small interfering RNA (siRNA) transfection determines the maturation status of dendritic cells, Journal of Immunological Methods 479.
- Dam, L.S. van; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2019), Clinical Implications of Excessive Neutrophil Extracellular Trap Formation in Renal Autoimmune Diseases, Kidney International Reports 4(2): 196-211.
- Arends, E.J.; Dam, L.S. van; Kraaij, T.; Kamerling, S.W.A.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2019), A High-throughput Assay to Assess and Quantify Neutrophil Extracellular Trap Formation, Journal of Visualized Experiments.
- Van Essen M, Schlagwein N, van Gijlswijk-Janssen D, Ruben J & van Kooten C (2019), PROPERDIN CONTRIBUTES TO THE T CELL STIMULATORY CAPACITY OF IMMATURE, BUT NOT MATURE, DENDRITIC CELLS, Molecular Immunology 114: 424-425.
- Leuning, D.G.; Witjas, F.M.R.; Maanaoui, M.; Graaf, A.M.A. de; Lievers, E.; Geuens, T.; Avramut, C.M.; Wiersma, L.E.; Berg, C.W. van den; Sol, W.M.P.J.; Boer, H. de; Wang, G.Q.; LaPointe, V.L.S.; Vlag, J. van der; Kooten, C. van; Berg, B.M. van den; Little, M.H.; Engelse, M.A. & Rabelink, T.J. (2019), Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell-derived endothelium, American Journal of Transplantation 19(5): 1328-1343.
- Bank, J.R.; Ruhaak, R.; Soonawala, D.; Mayboroda, O.; Romijn, F.P.; Kooten, C. van; Cobbaert, C.M. & Fijter, J.W. de (2019), Urinary TIMP-2 Predicts the Presence and Duration of Delayed Graft Function in Donation After Circulatory Death Kidney Transplant Recipients, Transplantation 103(5): 1014-1023.
- Groeneweg Koen, Reinders Marlies, Cobbaert Christa, Romijn Fred, van Kooten Cees & De Fijter Johan (2019), SERUM INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 (IGFBP7) AND TISSUE INHIBITOR OF METALLOPROTEINASES 2 (TIMP-2) LEVELS DECREASE AFTER SIMULTANEOUS PANCREAS KIDNEY TRANSPLANTATION (SPKT), Transplant International 32: 313-314.
- Essen, M.F. van; Ruben, J.M.; Vries, A.P.J. de; Kooten, C. van; Berger, S.; Born, J. van den; Gros, P.; Heuvel, L. van den; Kar, N. van de; Seelen, M.; Vries, A. de & COMBAT Consortium (2019), Role of properdin in complement-mediated kidney diseases, Nephrology Dialysis Transplantation 34(5): 742-750.
- Dam, L. van; Dirikgil, E.; Bredewold, E.; Ray, A.; Rabelink, T.; Kooten, C. van & Teng, O. (2019), ANCA Response upon Rituximab or Cyclophosphamide in ANCA-associated Vasculitis Patients, Arthritis and Rheumatology 71.
- Karahan, G.E.; Krop, J.; Wehmeier, C.; Vaal, Y.J.H. de; Langerak-Langerak, J.; Roelen, D.L.; Lardy, N.M.; Bemelman, F.J.; Berge, I.J.M. ten; Reinders, M.E.J.; Kooten, C. van; Claas, F.H.J. & Heidt, S. (2019), An Easy and Sensitive Method to Profile the Antibody Specificities of HLA-specific Memory B Cells, Transplantation 103(4): 716-723.
- Kraaij Tineke, Arends E. J., van Dam Laura, Kamerling Sylvia, van Daele Paul L. A., Bredewold Obbo Winne, Ray Argho, Bakker Jaap, Bajema Ingeborg, Scherer Hans Ulrich, Huizinga Thomas, Rabelink Ton, van Kooten Cees & Teng Y. K. Onno (2019), LONG-TERM EFFECTS OF SYNERGETIC B CELL IMMUNOMODULATION WITH RITUXIMAB AND BELIMUMAB COMBINATION TREATMENT IN SEVERE, REFRACTORY SLE: TWO YEAR RESULTS, Annals of the Rheumatic Diseases 78: 91-92.
- Zitur, L.J.; Chlebeck, P.J.; Odorico, S.K.; Danobeitia, J.S.; Zens, T.J.; Kooten, C. van; Eerhart, M.; Reyes, J.A.; Springer, M.L.; Coonen, J.M.; Brunner, K.G.; Capuano, S.V.; D'Alessandro, A.M. & Fernandez, L.A. (2019), Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression, Transplantation 103(9): 1821-1833.
- Barbour, S.J.; Coppo, R.; Zhang, H.; Liu, Z.H.; Suzuki, Y.; Matsuzaki, K.; Katafuchi, R.; Er, L.; Espino-Hernandez, G.; Kim, S.J.; Reich, H.N.; Feehally, J.; Cattran, D.C.; Russo, M.L.; Troyanov, S.; Cook, H.T.; Roberts, I.; Tesar, V.; Maixnerova, D.; Lundberg, S.; Gesualdo, L.; Emma, F.; Fuiano, L.; Beltrame, G.; Rollino, C.; Amore, A.; Camilla, R.; Peruzzi, L.; Praga, M.; Feriozzi, S.; Polci, R.; Segoloni, G.; Colla, L.; Pani, A.; Piras, D.; Angioi, A.; Cancarini, G.; Ravera, S.; Durlik, M.; Moggia, E.; Ballarin, J.; Giulio, S. di; Pugliese, F.; Serriello, I.; Caliskan, Y.; Sever, M.; Kilicaslan, I.; Locatelli, F.; Vecchio, L. del; Wetzels, J.F.M.; Peters, H.; Berg, U.; Carvalho, F.; Ferreira, A.C.D.; Maggio, M.; Wiecek, A.; Ots-Rosenberg, M.; Magistroni, R.; Topaloglu, R.; Bilginer, Y.; D'Amico, M.; Stangou, M.; Giacchino, F.; Goumenos, D.; Kalliakmani, P.; Gerolymos, M.; Galesic, K.; Geddes, C.; Siamopoulos, K.; Balafa, O.; Galliani, M.; Stratta, P.; Quaglia, M.; Bergia, R.; Cravero, R.; Salvadori, M.; Cirami, L.; Fellstrorn, B.; Smerud, H.K.; Ferrario, F.; Stellato, T.; Egido, J.; Martin, C.; Floege, J.; Eitner, F.; Lupo, A.; Bernich, P.; Mene, R.; Morosetti, M.; Kooten, C. van; Rabelink, T.; Reinders, M.E.J.; Grinyo, J.M.B.; Cusinato, S.; Benozzi, L.; Savoldi, S.; Licata, C.; Mizerska-Wasiak, M.; Martina, G.; Messuerotti, A.; Canton, A. dal; Esposito, C.; Migotto, C.; Triolo, G.; Mariano, F.; Pozzi, C.; Boero, R.; Bellur, S.; Mazzucco, G.; Giannakakis, C.; Honsova, E.; Sundelin, B.; Palma, A.M. di; Ferrario, F.; Gutierrez, E.; Asunis, A.M.; Barratt, J.; Tardanico, R.; Perkowska-Ptasinska, A.; Terroba, J.A.; Fortunato, M.; Pantzaki, A.; Ozluk, Y.; Steenbergen, E.; Soderberg, M.; Riispere, Z.; Furci, L.; Orhan, D.; Kipgen, D.; Casartelli, D.; Ljubanovic, D.G.; Gakiopoulou, H.; Bertoni, E.; Ortiz, P.C.; Karkoszka, H.; Groene, H.J.; Stoppacciaro, A.; Bajema, I.; Bruijn, J.; Oliveras, X.F.; Maldyk, J.; Loachim, E.; Bavbek, N.; Cook, T.; Troyanov, S.; Alpers, C.; Amore, A.; Barratt, J.; Berthoux, F.; Bonsib, S.; Bruijn, J.; D'Agati, V.; D'Amico, G.; Emancipator, S.; Emmal, F.; Ferrario, F.; Fervenza, F.; Florquin, S.; Fogo, A.; Geddes, C.; Groene, H.; Haas, M.; Hill, P.; Hogg, R.; Hsu, S.; Hunley, T.; Hladunewich; Jennette, C.; Joh, K.; Julian, B.; Kawamura, T.; Lai, F.; Leung, C.; Li, L.; Li, P.; Liu, Z.; Massat, A.; Mackinnon, B.; Mezzano, S.; Schena, F.; Tomino, Y.; Walker, P.; Wang, H.; Weening, J.; Yoshikawa, N.; Zeng, C.H.; Shi, S.F.; Nogi, C.; Suzuki, H.; Koike, K.; Hirano, K.; Kawamura, T.; Yokoo, T.; Hanai, M.; Fukami, K.; Takahashi, K.; Yuzawa, Y.; Niwa, M.; Yasuda, Y.; Maruyama, S.; Ichikawa, D.; Suzuki, T.; Shirai, S.; Fukuda, A.; Fujimoto, S.; Trimarchi, H. & Int IgA Nephropathy Network (2019), Evaluating a New International Risk-Prediction Tool in IgA Nephropathy, JAMA Internal Medicine 179(7): 942-952.
- Arends, E.J.; Dam, L.S. van; Kraaij, T.; Kamerling, S.W.A.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2019), A high-throughput assay to assess and quantify neutrophil extracellular trap formation, Journal of Visualized Experiments 143.
- Bos, R.M. van den; Pearce, N.M.; Granneman, J.; Brondijk, T.H.C.; Gros, P.; Berger, S.; Born, J. van den; Heuvel, L. van den; Kar, N. van de; Kooten, C. van; Seelen, M.; Vries, A. de; Gros, P. & COMBAT Consortium (2019), Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b, Frontiers in Immunology 10.
- Dam, L.S. van; Kraaij, T.; Kamerling, S.W.A.; Bakker, J.A.; Scherer, U.H.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2019), Intrinsically Distinct Role of Neutrophil Extracellular Trap Formation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Compared to Systemic Lupus Erythematosus, Arthritis and Rheumatology.
- Wang, L.; Vijayan, V.; Jang, M.S.; Thorenz, A.; Greite, R.; Rong, S.; Chen, R.J.; Shushakova, N.; Tudorache, I.; Derlin, K.; Pradhan, P.; Madyaningrana, K.; Madrahimov, N.; Brasen, J.H.; Lichtinghagen, R.; Kooten, C. van; Huber-Lang, M.; Haller, H.; Immenschuh, S. & Gueler, F. (2019), Labile Heme Aggravates Renal Inflammation and Complement Activation After Ischemia Reperfusion Injury, Frontiers in Immunology 10.
- Kolenbrander Kelsey, Schlagwein Nicole, van Gijlswijk-Janssen Danielle, Janssen George, van Veelen Peter, Thiel Steffen & van Kooten Cees (2019), MANNAN-BINDING LECTIN INDUCES RENAL EPITHELIAL CELL CYTOTOXICTY VIA BINDING OF THE CRD DOMAIN TO THE BASOLATERAL SIDE OF THESE CELLS, Molecular Immunology 114: 424-424.
- Dam, L. van; Oskam, J.; Kamerling, S.; Arends, E.; Bredewold, E.; Berkowska, M.; Dongen, J. van; Rabelink, T.; Kooten, C. van & Teng, O. (2019), Minimal Residual Autoimmunity After Rituximab in ANCA-associated Vasculitis Patients, Arthritis and Rheumatology 71.
- Karahan Gonca E., Wehmeier Caroline, Krop Juliette, de Vaal Yvonne, Langerak-Langerak Janneke, Roelen Dave, Lardy Neubury M., Bemelman Frederike, ten Berge Ineke, Reinders Marlies E., van Kooten Cees, Schaub Stefan, Claas Frans & Heidt Sebastiaan (2019), PRE-TRANSPLANT DONOR-SPECIFIC B CELL MEMORY FOR PREDICTION OF ANTIBODY MEDIATED REJECTION-A PILOT STUDY, Human Immunology 80: 52-52.
- Koopman, J.J.E.; Teng, Y.K.O.; Boon, C.J.F.; Heuvel, L.P. van den; Rabelink, T.J.; Kooten, C. van & Vries, A.P.J. de (2019), Diagnosis and treatment of C3 glomerulopathy in a center of expertise, Netherlands Journal of Medicine 77(1): 10-18.
- Kraaij, T.; Nilsson, S.C.; Kooten, C. van; Okroj, M.; Blom, A.M. & Teng, Y.K.O. (2019), Measuring plasma C4D to monitor immune complexes in lupus nephritis, Lupus Science & Medicine 6(1).
- Groot, N.; Shaikhani, D.; Teng, Y.K.O.; Leeuw, K. de; Bijl, M.; Dolhain, R.J.E.M.; Zirkzee, E.; Fritsch-Stork, R.; Bultink, I.E.M. & Kamphuis, S. (2019), Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus, Arthritis and Rheumatology 71(2): 290-301.
- Kraaij, T.; Kamerling, S.W.A.; Rooij, E.N.M. de; Daele, P.L.A. van; Bredewold, O.W.; Bakker, J.A.; Bajema, I.M.; Scherer, H.U.; Toes, R.E.M.; Huizinga, T.J.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2018), The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus, Journal of Autoimmunity 91: 45-54.
- Costa, M.G. da; Poppelaars, F.; Kooten, C. van; Mollnes, T.E.; Tedesco, F.; Wurzner, R.; Trouw, L.A.; Truedsson, L.; Daha, M.R.; Roos, A. & Seelen, M.A. (2018), Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population, Frontiers in Immunology 9.
- Alem, C.M.A. van; Boonstra, M.; Prins, J.; Bezhaeva, T.; Essen, M.F. van; Ruben, J.M.; Vahrmeijer, A.L.; Veer, E.P. van der; Fijter, J.W. de; Reinders, M.E.; Meijer, O.; Metselaar, J.M.; Kooten, C. van & Rotmans, J.I. (2018), Local delivery of liposomal prednisolone leads to an anti-inflammatory profile in renal ischaemia-reperfusion injury in the rat., Nephrology Dialysis Transplantation 33(1).
- Yang, J.X.; Snijders, M.L.H.; Haasnoot, G.W.; Kooten, C. van; Mallat, M.; Fijter, J.W. de; Clahsen-van Groningen, M.C.; Claas, F.H.J. & Eikmans, M. (2018), Elevated intragraft expression of innate immunity and cell death-related markers is a risk factor for adverse graft outcome, Transplant Immunology 48: 39-46.
- Bus, P.; Chua, J.S.; Klessens, C.Q.F.; Zandbergen, M.; Wolterbeek, R.; Kooten, C. van; Trouw, L.A.; Bruijn, J.A. & Baelde, H.J. (2018), Complement Activation in Patients With Diabetic Nephropathy, Kidney International Reports 3(2): 302-313.
- van Dam Laura, Kraaij Tineke, Kamerling Sylvia, Scherer Hans, Rabelink Ton, van Kooten Cees & Teng Y. (2018), EXCESSIVE FORMATION OF NEUTROPHIL EXTRACELLULAR TRAPS HAVE A DIFFERENT ROLE IN THE PATHOGENESIS OF ANCA-ASSOCIATED VASCULITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS, Nephrology Dialysis Transplantation 33: 329-U112.
- Kraaij, T.; Kamerling, S.W.A.; Dam, L.S. van; Bakker, J.A.; Bajema, I.M.; Page, T.; Brunini, F.; Pusey, C.D.; Toes, R.E.M.; Scherer, H.U.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2018), Excessive neutrophil extracellular trap formation in ANCA-associated vasculitis is independent of ANCA, Kidney International 94(1): 139-149.
- Dam, A.D. van; Beek, L. van; Pronk, A.C.M.; Berg, S.M. van den; Bossche, J. van den; Winther, M.P.J. de; Koning, F.; Kooten, C. van; Rensen, P.C.N.; Boon, M.R.; Verbeek, J.S.; Dijk, K.W. van & Harmelen, V. van (2018), IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fc gamma-receptor or complement, International Journal of Obesity 42(2): 260-269.
- Fransen, M.F.; Benonisson, H.; Maren, W.W. van; Sow, H.S.; Breuke, C.; Linssen, M.M.; Claassens, J.W.C.; Brouwers, C.; Kaa, J. van der; Camps, M.; Kleinovink, J.W.; Vonk, K.K.; Heiningen, S. van; Klar, N.; Beek, L. van; Harmelen, V. van; Daxinger, L.; Nandakumar, K.S.; Holmdahl, R.; Coward, C.; Lin, Q.S.; Hirose, S.; Salvatori, D.; Hall, T. van; Kooten, C. van; Mastroeni, P.; Ossendorp, F. & Verbeekt, J.S. (2018), A Restricted Role for Fc gamma R in the Regulation of Adaptive Immunity, Journal of Immunology 200(8): 2615-2626.
- Car Helena, Kramer Cynthia S. M., Brand-Schaaf Simone, Karahan Gonca E., Van Kooten Cees, Parren Paul W. H. I., Claas F. H. J., Roelen Dave L. & Heidt Sebastiaan (2018), OPTIMIZATION AND VALIDATION OF AN IGA HLA-SPECIFIC LUMINEX SINGLE ANTIGEN BEAD ASSAY, Hla 91(5): 369-369.
- Michailidou, I.; Jongejan, A.; Vreijling, J.P.; Georgakopoulou, T.; Wissel, M.B. de; Wolterman, R.A.; Ruizendaal, P.; Klar-Mohamad, N.; Grootemaat, A.E.; Picavet, D.I.; Kumar, V.; Kooten, C. van; Woodruff, T.M.; Morgan, B.P.; Wel, N.N. van der; Ramaglia, V.; Fluiter, K. & Baas, F. (2018), Systemic inhibition of the membrane attack complex impedes neuroinflammation in chronic relapsing experimental autoimmune encephalomyelitis, Acta Neuropathologica Communications 6.
- Leuning, D.G.; Beijer, N.R.M.; Fosse, N.A. du; Vermeulen, S.; Lievers, E.; Kooten, C. van; Rabelink, T.J. & Boer, J. de (2018), The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment, Scientific Reports 8.
- O'Flynn, J.; Kotimaa, J.; Faber-Krol, R.; Koekkoek, K.; Klar-Mohamad, N.; Koudijs, A.; Schwaeble, W.J.; Stover, C.; Daha, M.R. & Kooten, C. van (2018), Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease, Kidney International 94(6): 1141-1150.
- Bank J., Ruhaak R., Soonawala D., Romijn F., van Kooten C., Cobbaert C. & de Fijter H. (2018), Urinary TIMP-2 Predicts the Presence and Duration of Delayed Graft Function in DCD Kidney Transplant Recipients., American Journal of Transplantation 18: 495-495.
- Teng, Y.K.O.; Bredewold, E.O.W.; Rabelink, T.J.; Huizinga, T.W.J.; Eikenboom, H.C.J.; Limper, M.; Fritsch-Stork, R.D.E.; Bloemenkamp, K.W.M. & Sueters, M. (2018), An evidence-based approach to pre-pregnancy counselling for patients with systemic lupus erythematosus, Rheumatology 57(10): 1707-1720.
- Thorenz, A.; Derlin, K.; Schroder, C.; Dressler, L.; Vijayan, V.; Pradhan, P.; Immenschuh, S.; Jorns, A.; Echtermeyer, F.; Herzog, C.; Chen, R.J.; Rong, S.; Brasen, J.H.; Kooten, C. van; Kirsch, T.; Klemann, C.; Meier, M.; Klos, A.; Haller, H.; Hensen, B. & Gueler, F. (2018), Enhanced activation of interleukin-10, heme oxygenase-1, and AKT in C5aR2-deficient mice is associated with protection from ischemia reperfusion injury-induced inflammation and fibrosis, Kidney International 94(4): 741-755.
- Kostidis, S.; Bank, J.R.; Soonawala, D.; Nevedomskaya, E.; Kooten, C. van; Mayboroda, O.A. & Fijter, J.W. de (2018), Urinary metabolites predict prolonged duration of delayed graft function in DCD kidney transplant recipients., American Journal of Transplantation.
- van Dam Laura, Osmani Zgjim, Kraaij Tineke, Kamerling Sylvia, Bakker Jaap, Scherer Hans, Rabelink Ton, Voll Reinhard, Isenberg David, van Kooten Cees & Teng Y. (2018), THE EFFECT OF B CELL TARGETED THERAPIES ON AUTOANTIBODIES AND EXCESSIVE NEUTROPHIL EXTRACELLULAR TRAP FORMATION IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS, Nephrology Dialysis Transplantation 33.
- Rijnink, E.C.; Teng, Y.K.O.; Kraaij, T.; Dekkers, O.M.; Bruijn, J.A. & Bajema, I.M. (2018), Validation of the Systemic Lupus International Collaborating Clinics classification criteria in a cohort of patients with full house glomerular deposits, Kidney International 93(1): 214-220.
- Poppelaars, F.; Jager, N.M.; Kotimaa, J.; Leuvenink, H.G.D.; Daha, M.R.; Kooten, C. van; Seelen, M.A. & Damman, J. (2018), C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model, Transplantation 102(1): 79-87.
- Ruben, J.M.; Garcia-Romo, G.S.; Breman, E.; Kooij, S. van der; Redeker, A.; Arens, R. & Kooten, C. van (2018), Human plasmacytoid dendritic cells acquire phagocytic capacity by TLR9 ligation in the presence of soluble factors produced by renal epithelial cells, Kidney International 93(2): 355-364.
- Alem, C.M.A. van; Boonstra, M.; Prins, J.; Bezhaeva, T.; Essen, M.F. van; Ruben, J.M.; Vahrmeijer, A.L.; Veer, E.P. van der; Fijter, J.W. de; Reinders, M.E.; Meijer, O.; Metselaar, J.M.; Kooten, C. van & Rotmans, J.I. (2018), Local delivery of liposomal prednisolone leads to an anti-inflammatory profile in renal ischaemia-reperfusion injury in the rat, Nephrology Dialysis Transplantation 33(1): 44-53.
- Reinders, M.E.J.; Kooten, C. van; Rabelink, T.J. & Fijter, J.W. de (2018), Mesenchymal Stromal Cell Therapy for Solid Organ Transplantation, Transplantation 102(1): 35-43.
- Fuchs, A.; Gliwinski, M.; Grageda, N.; Spiering, R.; Abbas, A.K.; Appel, S.; Bacchetta, R.; Battaglia, M.; Berglund, D.; Blazar, B.; Bluestone, J.A.; Bornhauser, M.; Brinke, A. ten; Brusko, T.M.; Cools, N.; Cuturi, M.C.; Geissler, E.; Giannoukakis, N.; Golab, K.; Hafler, D.A.; Ham, S.M. van; Hester, J.; Hippen, K.; Ianni, M. di; Ilic, N.; Isaacs, J.; Issa, F.; Iwaszkiewicz-Grzes, D.; Jaeckel, E.; Joosten, I.; Klatzmann, D.; Koenen, H.; Kooten, C. van; Korsgren, O.; Kretschmer, K.; Levings, M.; Marek-Trzonkowska, N.M.; Martinez-Llordella, M.; Miljkovic, D.; Mills, K.H.G.; Miranda, J.P.; Piccirillo, C.A.; Putnam, A.L.; Ritter, T.; Roncarolo, M.G.; Sakaguchi, S.; Sanchez-Ramon, S.; Sawitzki, B.; Sofronic-Milosavljevic, L.; Sykes, M.; Tang, Q.Z.; Vives-Pi, M.; Waldmann, H.; Witkowski, P.; Wood, K.J.; Gregori, S.; Hilkens, C.M.U.; Lombardi, G.; Lord, P.; Martinez-Caceres, E.M. & Trzonkowski, P. (2018), Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization, Frontiers in Immunology 8.
- Rijnink, E.C.; Teng, Y.K.O.; Wilhelmus, S.; Almekinders, M.; Wolterbeek, R.; Cransberg, K.; Bruijn, J.A. & Bajema, I.M. (2017), Clinical and Histopathologic Characteristics Associated with Renal Outcomes in Lupus Nephritis, Clinical Journal of the American Society of Nephrology 12(5): 734-743.
- Rijnink, E.C.; Teng, Y.K.O.; Kraaij, T.; Wolterbeek, R.; Bruijn, J.A. & Bajema, I.M. (2017), Idiopathic non-lupus full-house nephropathy is associated with poor renal outcome, Nephrology Dialysis Transplantation 32(4): 654-662.
- Bajema, I.M.; Bruijn, J.A.; Casian, A.; Cid, M.C.; Csernok, E.; Daalen, E. van; Harper, L.; Hauser, T.; Little, M.A.; Luqmani, R.A.; Mahr, A.; Ponte, C.; Salama, A.; Segelmark, M.; Suzuki, K.; Sznajd, J.; Teng, Y.K.O.; Vaglio, A.; Westman, K. & Jayne, D. (2017), The European Vasculitis Society 2016 Meeting Report, Kidney International Reports 2(6): 1018-1031.
- Bank, J.R.; Pol, P. van der; Vreeken, D.; Monge-Chaubo, C.; Bajema, I.M.; Schlagwein, N.; Gijlswijk, D.J. van; Kooij, S.W. van der; Reinders, M.E.J.; Fijter, J.W. de & Kooten, C. van (2017), Kidney injury molecule-1 staining in renal allograft biopsies 10 days after transplantation is inversely correlated with functioning proximal tubular epithelial cells, Nephrology Dialysis Transplantation 32(12): 2132-2141.
- Kraaij, T.; Kamerling, S.W.A.; Rooij, E.N.M. de; Daele, P.L. van; Bredewold, O.W.; Bakker, J.A.; Bajema, I.; Scherer, H.U.; Toes, R.E.M.; Huizinga, T.W.J.; Rabelink, T.; Kooten, C. van & Teng, Y.K.O. (2017), Synergetic B-Cell Immunomodulation with Rituximab and Belimumab Combination Treatment in Severe, Refractory SLE, Arthritis and Rheumatology 69.
- Boels, M.G.S.; Koudijs, A.; Avramut, M.C.; Sol, W.M.P.J.; Wang, G.Q.; Oeveren-Rietdijk, A.M. van; Zonneveld, A.J. van; Boer, H.C. de; Vlag, J. van der; Kooten, C. van; Eulberg, D.; Berg, B.M. van den; IJpelaar, D.H.T. & Rabelink, T.J. (2017), Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy, The American Journal of Pathology 187(11): 2430-2440.
- Leuning, D.G.; Engelse, M.A.; Lievers, E.; Bijkerk, R.; Reinders, M.E.J.; Boer, H.C. de; Kooten, C. van & Rabelink, T.J. (2017), The human kidney capsule contains a functionally distinct mesenchymal stromal cell population, PLoS ONE 12(12).
- Dam, L.S. van; Kraaij, T.; Kamerling, S.W.; Avramut, M.C.; Jost, C.R.; Koster, A.J.; Scherer, H.U.; Pusey, C.D.; Rabelink, A.J.; Kooten, C. van & Teng, Y.K. (2017), ANCA-ASSOCIATED VASCULITIS- AND SYSTEMIC LUPUS ERYTHEMATOSUS-INDUCED NEUTROPHIL EXTRACELLULAR TRAPS HAVE INTRINSICALLY DIFFERENT FEATURES, Annals of the Rheumatic Diseases 76: 774-774.
- Leuning, D.G.; Lievers, E.; Reinders, M.E.J.; Kooten, C. van; Engelse, M.A. & Rabelink, T.J. (2017), A Novel Clinical Grade Isolation Method for Human Kidney Perivascular Stromal Cellse, Journal of Visualized Experiments.
- Essen, M. van; Nelemans, T.; Ruben, J. & Kooten, C. van (2017), CD40 ligation on antigen presenting cells (APCs) enhances properdin production, Molecular Immunology 89: 132-132.
- Poppelaars, F.; Werkhoven, M.B. van; Kotimaa, J.; Veldhuis, Z.J.; Ausema, A.; Broeren, S.G.M.; Damman, J.; Hempel, J.C.; Leuvenink, H.G.D.; Daha, M.R.; Son, W.J. van; Kooten, C. van; Os, R.P. van; Hillebrands, J.L. & Seelen, M.A. (2017), Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury, FASEB Journal 31(7): 3193-3204.
- Dam, L. van; Kraaij, T.; Kamerling, S.; Scherer, H.U.; Pusey, C.; Rabelink, T.; Kooten, C. van & Teng, O. (2017), Ex Vivo Induced Neutrophil Extracellular Traps Are Intrinsically Different in Anca-Associated Vasculitis and Systemic Lupus Erythematosus, Arthritis and Rheumatology 69.
- D'Orsogna, L.; Heuvel, H. van den; Kooten, C. van; Heidt, S. & Claas, F.H.J. (2017), Infectious pathogens may trigger specific allo-HLA reactivity via multiple mechanisms, Immunogenetics 69(8-9): 631-641.
- Bank, J.; Pol, P. van der; Vreeken, D.; Bajema, I.; Schlagwein, N.; Gijlswijk, D. van; Reinders, M.; Fijter, H. de & Kooten, C. van (2017), KIM-1 STAINING INTENSITY IN RENAL ALLOGRAFT BIOPSIES 10 DAYS POST TRANSPLANTATION IS INVERSELY CORRELATED WITH FUNCTIONING PROXIMAL TUBULAR EPITHELIAL CELLS, Transplant International 30: 397-397.
- Tati, R.; Kristoffersson, A.C.; Hedstrom, M.M.; Morgelin, M.; Wieslander, J.; Kooten, C. van & Karpman, D. (2017), Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney, EBioMedicine 16: 302-311.
- Lubbers, R.; Essen, M.F. van; Kooten, C. van & Trouw, L.A. (2017), Production of complement components by cells of the immune system, Clinical and Experimental Immunology 188(2): 183-194.
- Dixon, K.O.; O'Flynn, J.; Klar-Mohamad, N.; Daha, M.R. & Kooten, C. van (2017), Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-, European Journal of Immunology 47(3): 470-480.
- Kraaij, T.; Kamerling, S.W.; Bakker, J.A.; Huizinga, T.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K. (2017), SIGNIFICANT REDUCTIONS OF PATHOGENIC AUTOANTIBODIES BY SYNERGETIC RITUXIMAB AND BELIMUMAB TREATMENT EFFECTIVELY INHIBITS NEUTROPHIL EXTRACELLULAR TRAPS IN SEVERE, REFRACTORY SLE - THE SYNBIOSE STUDY, Annals of the Rheumatic Diseases 76: 181-181.
- Kraaij, T.; Kamerling, S.W.; Rooij, E. de; Daele, P.L. van; Bajema, I.; Bredewold, O.W.; Huizinga, T.W.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K. (2017), SYNERGETIC B-CELL IMMUNOMODULATION WITH RITUXIMAB AND BELIMUMAB IS CLINICALLY EFFECTIVE IN SEVERE AND REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS - THE SYNBIOSE PROOF-OF-CONCEPT STUDY, Annals of the Rheumatic Diseases 76: 871-871.
- Dijk, E.H.C. van; Tsonaka, R.; Klar-Mohamad, N.; Wouters, D.; Vries, A.P.J. de; Jong, E.K. de; Kooten, C. van & Boon, C.J.F. (2017), Systemic complement activation in central serous chorioretinopathy, PLoS ONE 12(7).
- Kostidis, S.; Bank, J.R.; Soonawala, D.; Nevedomskaya, E.; Kooten, C. van; Mayboroda, O.A. & Fijter, H.J.W. de (2017), URINARY METABOLIC PROFILES TO PREDICT PROLONGED DURATION OF DELAYED FUNCTION IN DCD KIDNEY TRANSPLANT RECIPIENT, Transplant International 30: 271-271.
- Leuning, D.G.; Reinders, M.E.J.; Li, J.; Peired, A.J.; Lievers, E.; Boer, H.C. de; Fibbe, W.E.; Romagnani, P.; Kooten, C. van; Little, M.H.; Engelse, M.A. & Rabelink, T.J. (2017), Clinical-Grade Isolated Human Kidney Perivascular Stromal Cells as an Organotypic Cell Source for Kidney Regenerative Medicine, Stem Cells Translational Medicine 6(2): 405-418.
- Bruin R.G. de, Shiue L., Prins J., Boer H.C. de, Singh A., Fagg W.S., Gils J.M. van, Duijs J.M., Katzman S., Kraaijeveld A.O., Böhringer S., Leung W.Y., Kielbasa S.M., Donahue J.P., Zande P.H. van der, Sijbom R., Alem C.M. van, Bot I., Kooten C. van, Jukema J.W., Esch H. van, Rabelink T.J., Kazan H., Biessen E.A., Ares M., Zonneveld A.J. van & Veer E.P. van der (2016), Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression, Nature Communications 2016(7): 10846.
- de Bruin RG, Shiue L, Prins J, de Boer HC, Singh A, Fagg WS, van Gils JM, Duijs JM, Katzman S, Kraaijeveld AO, Böhringer S, Leung WY, Kielbasa SM, Donahue JP, van der Zande PH, Sijbom R, van Alem CM, Bot I, van Kooten C, Jukema JW, Van Esch H, Rabelink TJ, Kazan H, Biessen EA, Ares M Jr, van Zonneveld AJ & van der Veer EP (2016), Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression., Nature Communications.
- Alem, C.M.A. van; Bezhaeva, T.; Boonstra, M.C.; Lalai, R.A.; Koudijs, A.; Metselaar, J.M.; Reinders, M.E.J.; Kooten, C. van & Rotmans, J.I. (2016), TARGETED DELIVERY OF LIPOSOMAL PREDNISOLONE AFTER RENAL ISCHEMIA REPERFUSION INJURY IN THE RAT, Nephrology Dialysis Transplantation 31: 63-64.
- Breman, E.; Ruben, J.M.; Franken, K.L.; Heemskerk, M.H.M.; Roelen, D.L.; Claas, F.H. & Kooten, C. van (2016), Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition, Journal of Immunology Research.
- Yang, J.X.; Haasnoot, G.W.; Kooten, C. van; Mallat, M.J.; Fijter, H.W. de; Bajema, I.M.; Claas, F.H.J. & Eikmans, M. (2016), ELEVATED INTRAGRAFT EXPRESSION OF INNATE IMMUNITY AND CELL DEATH-RELATED MARKERS CHARACTERISES DECEASED DONOR CONDITIONS AND IS A RISK FACTOR FOR ADVERSE GRAFT OUTCOME, HLA: Immune Response Genetics 87(4): 207-207.
- Kraaij T., Kamerling S., Bakker J., Pusey C., Scherer H. U., Toes R., Rabelink T., van Kooten C. & Teng O. (2016), ENHANCED CAPACITY OF MPO-ANCA COMPARED TO PR3-ANCA FOR INDUCING NEUTROPHIL EXTRACELLULAR TRAPS, Annals of the Rheumatic Diseases 75: 672-673.
- Kraaij Tineke, Kamerling Sylvia, Bakker Jaap, Brunini Francesca, Pusey Charles, Scherer Hans Ulrich, Toes Rene E. M., Rabelink Ton, van Kooten Cees & Teng Onno (2016), NET-Inducing Capacity Is a Biomarker in ANCA-Associated Vasculitis Independent of ANCA Antibodies, Arthritis and Rheumatology 68.
- Kooten, C. van; Pacchiarotta, T.; Pol, P. van der; Fijter, J. de; Schlagwein, N.; Gijlswijk, D. van & Mayboroda, O. (2016), ER Stress and Loss of GRP78 Expression Provides a Link Between Renal Ischemia/Reperfusion Injury and the Urinary Metabolome., American Journal of Transplantation 16: 638-638.
- Kraaij, T.; Tengstrom, F.C.; Kamerling, S.W.A.; Pusey, C.D.; Scherer, H.U.; Toes, R.E.M.; Rabelink, T.J.; Kooten, C. van & Teng, Y.K.O. (2016), A novel method for high-throughput detection and quantification of neutrophil extracellular traps reveals ROS-independent NET release with immune complexes, Autoimmunity Reviews 15(6): 577-584.
- Poppelaars, F.; Werkhoven, M. van; Kotimaa, J.; Veldhuis, Z.; Ausema, A.; Broeren, S.; Damman, J.; Hempel, C.; Leuvenink, H.; Daha, M.; Son, W. van; Kooten, C. van; Os, R. van; Hillebrands, J.L. & Seelen, M. (2016), A functional role for complement receptor C5L2 in the pathogenesis of renal ischemia-reperfusion injury, Immunobiology 221(10): 1183-1183.
- Bank J., Reinders M., Noordermeer L., Mallat M., Van der Kooij S., van Kooten C. & de Fijter J. (2016), Fractional Excretion of NGAL Instead of (99m)TcMAG(3) Renography to Monitor Resolution of Delayed Graft Function, American Journal of Transplantation 16: 661-661.
- Kooten, C. van; Rabelink, T.J.; Fijter, J.W. de & Reinders, M.E.J. (2016), Mesenchymal stromal cells in clinical kidney transplantation: how tolerant can it be?, Current Opinion in Organ Transplantation 21(6): 550-558.
- Lord, P.; Spiering, R.; Aguillon, J.C.; Anderson, A.E.; Appel, S.; Benitez-Ribas, D.; Brinke, A. ten; Broere, F.; Cools, N.; Cuturi, M.C.; Diboll, J.; Geissler, E.K.; Giannoukakis, N.; Gregori, S.; Ham, S.M. van; Lattimer, S.; Marshall, L.; Harry, R.A.; Hutchinson, J.A.; Isaacs, J.D.; Joosten, I.; Kooten, C. van; Cerio, A.L.D. de; Nikolic, T.; Oral, H.B.; Sofronic-Milosavljevic, L.; Ritter, T.; Riquelme, P.; Thomson, A.W.; Trucco, M.; Vives-Pi, M.; Martinez-Caceres, E.M. & Hilkens, C.M.U. (2016), Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies, PeerJ 4.
- Salih, M.; Demmers, J.A.; Berstarosti, K.; Leonhard, W.N.; Losekoot, M.; Kooten, C. van; Gansevoort, R.T.; Peters, D.J.M.; Zietse, R.; Hoorn, E.J. & DIPAK Consortium (2016), Proteomics of Urinary Vesicles Links Plakins and Complement to Polycystic Kidney Disease, Journal of the American Society of Nephrology 27(10): 3079-3092.
- Kotimaa, J.; Klar-Mohammad, N.; Gueler, F.; Schilders, G.; Jansen, A.; Rutjes, H.; Daha, M.R. & Kooten, C. van (2016), Sex matters: Systemic complement activity of female C57BL/6J and BALB/cJ mice is limited by serum terminal pathway components, Molecular Immunology 76: 13-21.
- Ruben, J.; Garcia-Romo, G.; Breman, E.; Kooij, S. van der; Redeker, A.; Arens, R. & Kooten, C. van (2016), Tissue Priming of Plasmacytoid Dendritic Cells Enhances Their Phagocytosis and Lowers the Threshold for Subsequent Toll-Like Receptor 7/9 Activation., American Journal of Transplantation 16: 718-718.
- Rekers, N.V.; Bajema, I.M.; Mallat, M.J.K.; Petersen, B.; Anholts, J.D.H.; Swings, G.M.J.S.; Miert, P.P.M.C. van; Kerkhoff, C.; Roth, J.; Popp, D.; Groningen, M.C. van; Baeten, D.; Goemaere, N.; Kraaij, M.D.; Zandbergen, M.; Heidt, S.; Kooten, C. van; Fijter, J.W. de; Claas, F.H.J. & Eikmans, M. (2016), Beneficial Immune Effects of Myeloid-Related Proteins in Kidney Transplant Rejection, American Journal of Transplantation 16(5): 1441-1455.
- Poppelaars F., Molenaars-Van Werkhoven M., Kotimaa J., Veldhuis Z., Ausema A., Damman J., Leuvenink H., Daha R., Van Son W., Van Kooten C., Van Os R., Hillebrands J. & Seelen M. (2016), C5L2 IN RENAL ISCHEMIA-REPERFUSION INJURY, Transplant International 29: 5-5.
- Yang, J.X.; Haasnoot, G.W.; Kooten, C. van; Mallat, M.J.; Fijter, H.W. de; Bajema, I.M.; Claas, F.H.J. & Eikmans, M. (2016), ELEVATED INTRAGRAFT EXPRESSION OF INNATE IMMUNITY AND CELL DEATH-RELATED MARKERS CHARACTERISES DECEASED DONOR CONDITIONS AND IS A RISK FACTOR FOR ADVERSE GRAFT OUTCOME, Hla 87(4): 207-207.
- Eikmans, M.; Yang, J.; Haasnoot, G.; Kooten, C. van; Mallat, M.; Fijter, H. de; Bajema, I. & Claas, F. (2016), Elevated Intragraft Expression of Innate Immunity and Cell Death-Related Markers Characterizes Deceased Donor Conditions and Is a Risk Factor for Adverse Graft Outcome., American Journal of Transplantation 16: 277-277.
- Pont, M.J.; Honders, M.W.; Kremer, A.N.; Kooten, C. van; Out, C.; Hiemstra, P.S.; Boer, H.C. de; Jager, M.J.; Schmelzer, E.; Vries, R.G.; Hinai, A.S. al; Kroes, W.G.; Monajemi, R.; Goeman, J.J.; Bohringer, S.; Marijt, W.A.F.; Falkenburg, J.H.F. & Griffioen, M. (2016), Microarray Gene Expression Analysis to Evaluate Cell Type Specific Expression of Targets Relevant for Immunotherapy of Hematological Malignancies, PLoS ONE 11(5).
- O'Flynn, J.; Pol, P. van der; Dixon, K.O.; Prohaszka, Z.; Daha, M.R. & Kooten, C. van (2016), Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin, AJP - Renal Physiology 310(11): F1308-F1316.
- Bruin, R.G. de; Shiue, L.; Prins, J.; Boer, H.C. de; Singh, A.; Fagg, W.S.; Gils, J.M. van; Duijs, J.M.G.J.; Katzman, S.; Kraaijeveld, A.O.; Bohringer, S.; Leung, W.Y.; Kielbasa, S.M.; Donahue, J.P.; Zande, P.H.J. van der; Sijbom, R.; Alem, C.M.A. van; Bot, I.; Kooten, C. van; Jukema, J.W.; Esch, H. van; Rabelink, T.J.; Kazan, H.; Biessen, E.A.L.; Ares, M.; Zonneveld, A.J. van & Veer, E.P. van der (2016), Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression, Nature Communications 7.
- Daha, M.R. & Kooten, C. van (2016), Role of complement in IgA nephropathy, Journal of Nephrology 29(1): 1-4.
- Kotimaa, J.; Klar-Mohammad, N.; Schilders, G.; Binsbergen, J. van; Daha, M. & Kooten, C. van (2015), Sex matters: Systemic complement activity of female C57bl/6 mice is limited by serum terminal pathway components, Molecular Immunology 67(1): 152-153.
- Kraaij, T.; Kamerling, S.; Rabelink, T.; Toes, R.E.M.; Kooten, C. van & Teng, O. (2015), A High-Throughput System for Quantification of in Vitro Neutrophil Extracellular Trap Formation with Fluorescence Immunocytochemistry, Arthritis and Rheumatology 67.
- Bank, J.; Reinders, M.; Mallat, M.; Schlagwein, N.; Kooij, S. van der; Gijlswijk, D. van; Bajema, I.; Kooten, C. van & Fijter, H. de (2015), Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients, American Journal of Transplantation 15.
- Schaarenburg, R.A. van; Daha, N.A.; Schonkeren, J.J.M.; Levarht, E.W.N.; Gijlswijk-Janssen, D.J. van; Kurreeman, F.A.S.; Roos, A.; Kooten, C. van; Koelman, C.A.; Ernst-Kruis, M.R.; Toes, R.E.M.; Huizinga, T.W.J.; Lankester, A.C. & Trouw, L.A. (2015), Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections, Immunobiology 220(3): 422-427.
- Micha Dimitra, Guo Dong-chuan, Hilhorst-Hofstee Yvonne, van Kooten Fop, Atmaja Dian, Overwater Eline, Cayami Ferdy K., Regalado Ellen S., van Uffelen Rene, Venselaar Hanka, Faradz Sultana M. H., Vriend Gerrit, Weiss Marjan M., Sistermans Erik A., Maugeri Alessandra, Milewicz Dianna M., Pals Gerard & van Dijk Fleur S. (2015), SMAD2 Mutations Are Associated with Arterial Aneurysms and Dissections, Human Mutation 36(12): 1145-1149.
- Reinders, M.E.J.; Dreyer, G.J.; Bank, J.R.; Roelofs, H.; Heidt, S.; Roelen, D.L.; Zandvliet, M.L.; Huurman, V.A.L.; Fibbe, W.E.; Kooten, C. van; Claas, F.H.J.; Rabelink, T.J. & Fijter, J.W. de (2015), Safety of allogeneic bone marrow derived mesenchymal stromal cell therapy in renal transplant recipients: the neptune study, Journal of Translational Medicine 13.
- Kooiman, J.; Peppel, W.R. van de; Sijpkens, Y.W.J.; Brulez, H.F.H.; Vries, P.M. de; Nicolaie, M.A.; Putter, H.; Huisman, M.V.; Kooij, W. van der; Kooten, C. van & Rabelink, T.J. (2015), No increase in Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin excretion following intravenous contrast enhanced-CT, European Radiology 25(7): 1926-1934.
- Penning, M.; Chua, J.S.; Kooten, C. van; Zandbergen, M.; Buurma, A.; Schutte, J.; Bruijn, J.A.; Khankin, E.V.; Bloemenkamp, K.; Karumanchi, S.A. & Baelde, H. (2015), Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia, Hypertension 66(1): 117-125.
- Penning, M.E.; Chua, J.; Kooten, C. van; Buurma, A.; Bruijn, J.A.; Bajema, I.; Khankin, E.V.; Bloemenkamp, K.; Karumanchi, A. & Baelde, H.J. (2015), Complement Activation in the Kidney During Preeclampsia, Reproductive Sciences 22: 295A-295A.
- Kotimaa, J.P.; Werkhoven, M.B. van; O'Flynn, J.; Klar-Mohamad, N.; Groningen, J. van; Schilders, G.; Rutjes, H.; Daha, M.R.; Seelen, M.A. & Kooten, C. van (2015), Functional assessment of mouse complement pathway activities. and quantification of C3b/C3c/iC3b in an experimental model of mouse renal ischaemia/reperfusion injury, Journal of Immunological Methods 419: 25-34.
- Dixon, K.O.; Kooij, S.W. van der; Vignali, D.A.A. & Kooten, C. van (2015), Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members, European Journal of Immunology 45(6): 1736-1747.
- Schaarenburg, R.A. van; Daha, N.A.; Schonkeren, J.J.M.; Levarht, E.W.N.; Gijlswijk-Janssen, D.J. van; Kurreeman, F.A.S.; Roos, A.; Kooten, C. van; Koelman, C.A.; Ernst-Kruis, M.R.; Toes, R.E.M.; Huizinga, T.W.J.; Lankester, A.C. & Trouw, L.A. (2015), Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections, Immunobiology 220(3): 422-427.
- Shushimita, S.; Pol, P. van der; Bruin, R.W.F. de; Ijzermans, J.N.M.; Kooten, C. van & Dor, F.J.M.F. (2015), Mannan-Binding Lectin Is Involved in the Protection against Renal Ischemia/Reperfusion Injury by Dietary Restriction.
- Breman, E.; Miert, P.P. van; Steen, D.M. van der; Heemskerk, M.H.; Doxiadis, I.I.; Roelen, D.; Claas, F.H. & Kooten, C. van (2014), HLA monomers as a tool to monitor indirect allorecognition., Transplantation.
- Berge, I. ten; Heutinck, K.; Yapici, U.; Stokman, G.; Florquin, S.; Kooten, C. van; Garcia-Romo, G.; Ruben, J.; Vrie, M. van de; Hilbrands, L.; Michelo, C.; Joosten, I.; Heuvel, H. van den & Claas, F. (2014), The interplay between antiviral immunity and allo-immune reactivity after renal transplantation Consortium between the Centres Amsterdam, Leiden and Nijmegen (ALLOVIR), Transplant Immunology 31(4): 191-194.
- Dixon, K.O.; O'Flynn, J.; Kooij, S.W. van der & Kooten, C. van (2014), Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells, Journal of Leukocyte Biology 96(2): 313-324.
- Heidt, S.; Eikmans, M.; Roelen, D.L.; Kooten, C. van & Claas, F.H.J. (2014), Immunogenetics and immunology of transplantation in Leiden, Transplant Immunology 31(4): 195-199.
- Dixon, K.O.; Rossmann, L.; Kamerling, S.W.A. & Kooten, C. van (2014), Human renal fibroblasts generate dendritic cells with a unique regulatory profile, Immunology and Cell Biology 92(8): 688-698.
- Rood, J.J. van; Claas, F.H.J.; Brand, A.; Tilanus, M.G.J. & Kooten, C. van (2014), Half a century of Dutch transplant immunology, Immunology Letters 162(2): 145-149.
- Kotimaa, J.; Pol, P. van der; Leijtens, S.; Klar-Mohammad, N.; Schilders, G.; Daha, M.R.; Rutjes, H. & Kooten, C. van (2014), Functional assessment of rat complement pathway activities and quantification of soluble C5b-9 in an experimental model of renal ischemia/reperfusion injury, Journal of Immunological Methods 412: 14-23.
- Pol, P. van der; Gijlswijk-Jansen, D. van; Bijkerk, R.; Koning, E. de; Fijter, J. de; Kooten, C. van & Reinders, M. (2014), Elevated MBL Levels in Type 1 Diabetic Patients Are Reversed After Simultaneous Pancreas-Kidney Transplantation, Transplantation 98: 219-219.
- Bijkerk, R.; Solingen, C. van; Boer, H.C. de; Pol, P. van der; Khairoun, M.; Bruin, R.G. de; Oeveren-Rietdijk, A.M. van; Lievers, E.; Schlagwein, N.; Gijlswijk, D.J. van; Roeten, M.K.; Neshati, Z.; Vries, A.A.F. de; Rodijk, M.; Pike-Overzet, K.; Berg, Y.W. van den; Veer, E.P. van der; Versteeg, H.H.; Reinders, M.E.J.; Staal, F.J.T.; Kooten, C. van; Rabelink, T.J. & Zonneveld, A.J. van (2014), eHematopoietic MicroRNA-126 Protects against Renal Ischemia/Reperfusion Injury by Promoting Vascular Integrity, Journal of the American Society of Nephrology 25(8): 1710-1722.
- Klop, B.; Pol, P. van der; Bruggen, R. van; Wang, Y.A.; Vries, M.A. de; Santen, S. van; O'Flynn, J.; Geijn, G.J.M. van de; Njo, T.L.; Janssen, H.W.; Man, P. de; Jukema, J.W.; Rabelink, T.J.; Rensen, P.C.N.; Kooten, C. van & Cabezas, M.C. (2014), Differential Complement Activation Pathways Promote C3b Deposition on Native and Acetylated LDL thereby Inducing Lipoprotein Binding to the Complement Receptor 1, Journal of Biological Chemistry 289(51): 35421-35430.
- Reinders, M.E.J.; Bank, J.R.; Dreyer, G.J.; Roelofs, H.; Heidt, S.; Roelen, D.L.; Huurman, V.A.L.; Lindeman, J.; Kooten, C. van; Claas, F.H.J.; Fibbe, W.E.; Rabelink, T.J. & Fijter, J.W. de (2014), Autologous bone marrow derived mesenchymal stromal cell therapy in combination with everolimus to preserve renal structure and function in renal transplant recipients, Journal of Translational Medicine 12.
- Kraaij, M.D.; Koekkoek, K.M.; Gelderman, K.A. & Kooten, C. van (2014), The NOX2-mediated ROS producing capacity of recipient cells is associated with reduced T cell infiltrate in an experimental model of chronic renal allograft inflammation, Transplant Immunology 30(2-3): 65-70.
- Shushimita, S.; Pol, P. van der; Bruin, R. de; IJzermans, J.; Kooten, C. van & Dor, F.M.F. (2014), Protection Against Renal Ischemia Reperfusion Injury By Dietary Restriction and Fasting Through Downregulation of Mannan-Binding Lectin., Transplantation 98: 349-349.
- Shushimita, S.; Pol, P. van der; Bruin, R.W.F. de; Ijzermans, J.N.M.; Kooten, C. van & Dor, F.J.M.F. (2014), PROTECTION AGAINST RENAL ISCHEMIA REPERFUSION INJURY BY DIETARY RESTRICTION AND FASTING THROUGH DOWNREGULATION OF MANNAN-BINDING LECTIN, Transplant International 27: 3-3.
- Shushimita, S.; Pol, P. van der; Bruin, R. de; IJzermans, J.; Kooten, C. van & Dor, F.M.F. (2014), Protection Against Renal Ischemia Reperfusion Injury By Dietary Restriction and Fasting Through Downregulation of Mannan-Binding Lectin, American Journal of Transplantation 14: 349-349.
- O'Flynn, J.; Dixon, K.O.; Krol, M.C.F.; Daha, M.R. & Kooten, C. van (2014), Myeloperoxidase Directs Properdin-Mediated Complement Activation, Journal of Innate Immunity 6(4): 417-425.
- Breman, E.; Miert, P.P. van; Steen, D.M. van der; Heemskerk, M.H.; Doxiadis, I.I.; Roelen, D.; Claas, F.H. & Kooten, C. van (2014), HLA Monomers as a Tool to Monitor Indirect Allorecognition, Transplantation 97(11): 1119-1127.
- Ditonno, P.; Kooten, C. van; Gesualdo, L.; Grandaliano, G. & Lucarelli, G. (2014), Emerging Biomarkers in Renal Damage, BioMed Research International.
- Pol, P. van der; Gijlswijk-Jansen, D. van; Bijkerk, R.; Koning, E. de; Fijter, J. de; Kooten, C. van & Reinders, M. (2014), Elevated MBL Levels in Type 1 Diabetic Patients Are Reversed After Simultaneous Pancreas-Kidney Transplantation., American Journal of Transplantation 14: 219-219.
- Kort, H. de; Mallat, M.J.K.; Kooten, C. van; Heer, E. de; Brand-Schaaf, S.H.; Wal, A.M. van der; Roufosse, C.; Roelen, D.L.; Bruijn, J.A.; Claas, F.H.; Fijter, J.W. de & Bajema, I.M. (2014), Diagnosis of Early Pancreas Graft Failure via Antibody-Mediated Rejection: Single-Center Experience With 256 Pancreas Transplantations, American Journal of Transplantation 14(4): 936-942.
- Eikmans, M.; Rekers, N.; Bajema, I.; Mallat, M.; Anholts, J.; Swings, G.; Miert, P. van; Kerkhoff, C.; Roth, J.; Kooten, C. van; Clahsen-van Groningen, M.; Fijter, J. de & Claas, F. (2014), Beneficial Effects of High S100A9 Expression On Graft Infiltrating Myeloid Cells in Kidney Transplantation., Transplantation 98: 229-229.
- Eikmans, M.; Rekers, N.; Bajema, I.; Mallat, M.; Anholts, J.; Swings, G.; Miert, P. van; Kerkhoff, C.; Roth, J.; Kooten, C. van; Clahsen-van Groningen, M.; Fijter, J. de & Claas, F. (2014), Beneficial Effects of High S100A9 Expression On Graft Infiltrating Myeloid Cells in Kidney Transplantation, American Journal of Transplantation 14: 229-229.
- Leuning, D.; Reinders, M.; Lievers, E.; Duijs, J.; Zonneveld, A.J. van; Kooten, C. van; Engelse, M. & Rabelink, T. (2014), A NOVEL METHOD TO ISOLATE HUMAN KIDNEY DERIVED MESENCHYMAL STROMAL CELLS, Nephrology Dialysis Transplantation 29: 536-537.
- Brinke, A. ten; Joosten, I.; Ham, S.M. van; Kooten, C. van & Prakken, B.J. (2014), Redefining strategies to introduce tolerance-inducing cellular therapy in human beings to combat autoimmunit and transplantation reactions, Frontiers in Immunology 5.
- Bijkerk, R.; Solingen, C. van; Boer, H.C. de; Pol, P. van der; Khairoun, M.; Bruin, R.G. de; Oeveren-Rietdijk, A.M. van; Lievers, E.; Schlagwein, N.; Gijlswijk, D.J. van; Roeten, M.K.; Neshati, Z.; Vries, A.A.F. de; Rodijk, M.; Pike-Overzet, K.; Berg, Y.W. van den; Veer, E.P. van der; Versteeg, H.H.; Reinders, M.E.J.; Staal, F.J.T.; Kooten, C. van; Rabelink, T.J. & Zonneveld, A.J. van (2014), Hematopoietic overexpression of miR-126 promotes vasculogenesis and protects against renal ischemia reperfusion injury by promoting vascular integrity, Angiogenesis 17(3): 765-765.
- Mauriello, C.T.; Pallera, H.K.; Sharp, J.A.; Woltmann, J.L.; Qian, S.Z.; Hair, P.S.; Pol, P. van der; Kooten, C. van; Thielens, N.M.; Lattanzio, F.A.; Cunnion, K.M. & Krishna, N.K. (2013), A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility, Molecular Immunology 53(1-2): 132-139.
- Reinders, M.; Vries, D. de; Khairoun, M.; Lindeman, J.; Bajema, I.; Heer, E. de; Roest, M.; Zonneveld, A. van; Kooten, C. van; Schaapherder, A. & Rabelink, T. (2013), Renal Ischemia/Reperfusion Induces Release of Angiopoietin-2 from Human Grafts of Living and Deceased Donors., American Journal of Transplantation 13: 409-409.
- Shushimita, S.; Pol, P. van der; Bruin, R. de; IJzermans, J.; Kooten, C. van & Dor, F. (2013), Downregulation of Complement Activity Via the Mannan-Binding Lectin (MBL) Pathway by Dietary Restriction and Fasting., American Journal of Transplantation 13: 491-491.
- Khairoun, M.; Pol, P. van der; Vries, D.K. de; Lievers, E.; Schlagwein, N.; Boer, H.C. de; Bajema, I.M.; Rotmans, J.I.; Zonneveld, A.J. van; Rabelink, T.J.; Kooten, C. van & Reinders, M.E.J. (2013), Renal ischemia-reperfusion induces a dysbalance of angiopoietins, accompanied by proliferation of pericytes and fibrosis, American Journal of Physiology - Renal Physiology 305(6): F901-F910.
- Kraaij, M.D.; Koekkoek, K.M.; Kooij, S.W. van der; Gelderman, K.A. & Kooten, C. van (2013), Subsets of human type 2 macrophages show differential capacity to produce reactive oxygen species, Cellular Immunology 284(1-2): 1-8.
- Vries, D.K. de; Pol, P. van der; Anken, G.E. van; Gijlswijk, D.J. van; Damman, J.; Lindeman, J.H.; Reinders, M.E.J.; Schaapherder, A.F. & Kooten, C. van (2013), Acute But Transient Release of Terminal Complement Complex After Reperfusion in Clinical Kidney Transplantation, Transplantation 95(6): 816-820.
- Reinders, M.E.J.; Fijter, J.W. de; Roelofs, H.; Bajema, I.M.; Vries, D.K. de; Schaapherder, A.F.; Claas, F.H.J.; Miert, P.P.M.C. van; Roelen, D.L.; Kooten, C. van; Fibbe, W.E. & Rabelink, T.J. (2013), Autologous Bone Marrow-Derived Mesenchymal Stromal Cells for the Treatment of Allograft Rejection After Renal Transplantation: Results of a Phase I Study, Stem Cells Translational Medicine 2(2): 107-111.
- Xu, W.; Zhao, X.W.; Daha, M.R. & Kooten, C. van (2013), Reversible differentiation of pro- and anti-inflammatory macrophages, Molecular Immunology 53(3): 179-186.
- Franquesa, M.; Hoogduijn, M.J.; Reinders, M.E.; Eggenhofer, E.; Engela, A.U.; Mensah, F.K.; Torras, J.; Pileggi, A.; Kooten, C. van; Mahon, B.; Detry, O.; Popp, F.C.; Benseler, V.; Casiraghi, F.; Johnson, C.; Ancans, J.; Fillenberg, B.; delaRosa, O.; Aran, J.M.; Roemeling-vanRhijn, M.; Pinxteren, J.; Perico, N.; Gotti, E.; Christ, B.; Reading, J.; Introna, M.; Deans, R.; Shagidulin, M.; Farre, R.; Rambaldi, A.; Sanchez-Fueyo, A.; Obermajer, N.; Pulin, A.; Dor, F.J.M.F.; Portero-Sanchez, I.; Baan, C.C.; Rabelink, T.J.; Remuzzi, G.; Betjes, M.G.H.; Dahlke, M.H.; Grinyo, J.M. & MiSOT Study Grp (2013), Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: Lessons Learned from First Clinical Trials, Transplantation 96(3): 234-238.
- Yu, H.X.; Segers, F.; Sliedregt-Bol, K.; Bot, I.; Woltman, A.M.; Boross, P.; Verbeek, S.; Overkleeft, H.; Marel, G.A. van der; Kooten, C. van; Berkel, T.J.C. van & Biessen, E.A.L. (2013), Identification of a novel CD40 ligand for targeted imaging of inflammatory plaques by phage display, FASEB Journal 27(10): 4136-4146.
- O'Flynn, J.; Dixon, K.; Krol, M.C.F.; Daha, M.R. & Kooten, C. van (2013), Neutrophil components as regulators of the complement system, Molecular Immunology 56(3): 245-245.
- Kotimaa, J.; Pol, P. van der; Leijtens, S.; Klar-Mohamad, N.; Rutjes, H.; Daha, M.R. & Kooten, C. van (2013), Measurement of soluble C5b-9 and pathway specific complement activation in a rat model of renal ischemia/reperfusion injury, Molecular Immunology 56(3): 270-270.
- Vries, D.K. de; Khairoun, M.; Lindeman, J.H.N.; Bajema, I.M.; Heer, E. de; Roest, M.; Zonneveld, A.J. van; Kooten, C. van; Rabelink, T.J.; Schaapherder, A.F. & Reinders, M.E.J. (2013), Renal Ischemia-Reperfusion Induces Release of Angiopoietin-2 From Human Grafts of Living and Deceased Donors, Transplantation 96(3): 282-289.
- Daha, M.R. & Kooten, C. van (2013), Deposition of IgA in primary IgA nephropathy: it takes at least four to tango, Nephrology Dialysis Transplantation 28(4): 794-797.
- Reinders, M.; Fijter, J. de; Roelofs, H.; Vries, D. de; Claas, F.; Miert, P. van; Roelen, D.; Kooten, C. van & Rabelink, T. (2013), Treatment of Renal Transplant Patients with Autologous Bone Marrow Derived Mesenchymal Stromal Cells Downregulates the Donor Specific Mixed Lymphocyte Reaction., American Journal of Transplantation 13: 340-340.
- Kotimaa, J.; O'flynn, J.; Groningen, J. van; Schilders, G.; Daha, M.R. & Kooten, C. van (2013), Functional assessment of the three complement pathways of mouse complement system and quantification of mouse C3b/C3c/iC3b complex in circulation, Molecular Immunology 56(3): 270-271.
- O'Flynn, J.; Dixon, K.; Mohamad, N.K.; Daha, M.R. & Kooten, C. van (2013), Dendritic cells express alternative pathway components properdin and factor H: Differential regulation by Interferons and IL-27, Molecular Immunology 56(3): 263-263.
- Shushimita, S.; Pol, P. van der; Bruin, R.W.F. de; Ijzermans, J.N.M.; Kooten, C. van & Dor, F.J.M.F. (2013), DIETARY RESTRICTION AND FASTING PROTECTS AGAINST RENAL ISCHEMIA-REPERFUSION INJURY VIA MBL-PATHWAY, Transplant International 26: 159-159.
- Reinders, M.E.J.; Roemeling-van Rhijn, M.; Khairoun, M.; Lievers, E.; Vries, D.K. de; Schaapherder, A.F.M.; Wong, S.W.S.; Zwaginga, J.J.; Duijs, J.M.; Zonneveld, A.J. van; Hoogduijn, M.J.; Fibbe, W.E.; Fijter, J.W. de; Kooten, C. van; Rabelink, T.J. & Roelofs, H. (2013), Bone marrow-derived mesenchymal stromal cells from patients with end-stage renal disease are suitable for autologous therapy, Cytotherapy 15(6): 663-672.
- Eikmans, M.; Canck, I. de; Pol, P. van der; Baan, C.C.; Haasnoot, G.W.; Mallat, M.J.K.; Vergunst, M.; Meester, E. de; Roodnat, J.I.; Anholts, J.D.H.; Thielen, M. van; Doxiadis, I.I.N.; Fijter, H.W. de; Linden, C.J.E. van der; Beelen, E. van; Kooten, C. van; Kal-van Gestel, J.; Peeters, A.M.A.; Weimar, W.; Roelen, D.L.; Rossau, R. & Claas, F.H.J. (2012), The Functional Polymorphism Ala258Ser in Ficolin-2 in the Donor Kidney Predicts Improved Renal Transplant Outcome, American Journal of Transplantation 12: 312-312.
- Zaferani, A.; Vives, R.R.; Pol, P. van der; Navis, G.J.; Daha, M.R.; Kooten, C. van; Lortat-Jacob, H.; Seelen, M.A. & Born, J. van den (2012), Factor H and Properdin Recognize Different Epitopes on Renal Tubular Epithelial Heparan Sulfate, Journal of Biological Chemistry 287(37): 31471-31481.
- Shushimita, S.; Pol, P. van der; Bruin, R.W.F. de; IJzermans, J.N.M.; Kooten, C. van & Dor, F.J.M.F. (2012), Dietary restriction and fasting downregulate upstream as well as downstream complement proteins and activity, Immunology 137: 124-124.
- Kort, H. de; Crul, C.; Wal, A.M. van der; Schlagwein, N.; Stax, A.M.; Bruijn, J.A.; Kooten, C. van & Heer, E. de (2012), Accelerated Antibody-Mediated Graft Loss of Rodent Pancreatic Islets After Pretreatment With Dexamethasone-Treated Immature Donor Dendritic Cells, Transplantation 94(9): 903-910.
- Kortekaas, K.A.; Pol, P. van der; Lindeman, J.H.N.; Baan, C.C.; Kooten, C. van & Klautz, R.J.M. (2012), No prominent role for terminal complement activation in the early myocardial reperfusion phase following cardiac surgery.
- Castellano, G.; Divella, C.; Loverre, A.; Stasi, A.; Curci, C.; Rossini, M.; Ditonno, P.; Battaglia, M.; Daha, M.R.; Kooten, C. van; Gesualdo, L.; Schena, F.P. & Grandaliano, G. (2012), COMPLEMENT (C) ACTIVATION IN RENAL ISCHEMIA/REPERFUSION (I/R) INJURY IS MEDIATED BY PENTRAXIN 3 (PTX3): A SPECIES-SPECIFIC DIFFERENCE, Nephrology Dialysis Transplantation 27: 339-339.
- Zuidwijk, K.; Fijter, J.W. de; Mallat, M.J.K.; Eikmans, M.; Groningen, M.C. van; Goemaere, N.N.; Bajema, I.M. & Kooten, C. van (2012), Increased influx of myeloid dendritic cells during acute rejection is associated with interstitial fibrosis and tubular atrophy and predicts poor outcome, Kidney International 81(1): 64-75.
- Kotimaa, J.P.; Leijtens, S.; Daha, M.R.; Kooten, C. van & Rutjes, H.W.H. (2012), Robust measurement of rat complement system activation with novel ELISA-based assays, Immunobiology 217(11): 1199-1200.
- Eikmans, M.; Canck, I. de; Pol, P. van der; Baan, C.C.; Haasnoot, G.W.; Mallat, M.J.K.; Vergunst, M.; Meester, E. de; Roodnat, J.I.; Anholts, J.D.H.; Thielen, M. van; Doxiadis, I.I.N.; Fijter, J.W. de; Linden, P.J.E. van der; Beelen, E. van; Kooten, C. van; Kal-van Gestel, J.A.; Peeters, A.M.A.; Weimar, W.; Roelen, D.L.; Rossau, R. & Claas, F.H.J. (2012), The Functional Polymorphism Ala258Ser in the Innate Receptor Gene Ficolin-2 in the Donor Predicts Improved Renal Transplant Outcome, Transplantation 94(5): 478-485.
- Kraaij, M.D.; Koekkoek, K.M.; Kooij, S.W. van der; Gelderman, K.A. & Kooten, C. van (2012), Subsets of alternatively activated human macrophages show differential capacity to produce reactive oxygen species, Immunology 137: 282-282.
- Dixon, K.; Kooij, S. van der; Schlagwein, N.; Vignali, D.A. & Kooten, C. van (2012), Role of human tolerogenic dendritic cell derived IL-35 in regulating T cell responses, Cytokine 59(3): 515-515.
- Rekers, N.V.; Bajema, I.M.; Mallat, M.J.K.; Zuidwijk, K.; Anholts, J.D.H.; Goemaere, N.; Haasnoot, G.W.; Groningen, M.C. van; Kooten, C. van; Fijter, J.W. de; Claas, F.H.J. & Eikmans, M. (2012), Quantitative Polymerase Chain Reaction Profiling of Immunomarkers in Rejecting Kidney Allografts for Predicting Response to Steroid Treatment, Transplantation 94(6): 596-602.
- Pol, P. van der; Schlagwein, N.; Gijlswijk, D.J. van; Berger, S.P.; Roos, A.; Bajema, I.M.; Boer, H.C. de; Fijter, J.W. de; Stahl, G.L.; Daha, M.R. & Kooten, C. van (2012), Mannan-Binding Lectin Mediates Renal Ischemia/Reperfusion Injury Independent of Complement Activation, American Journal of Transplantation 12(4): 877-887.
- Castellano, G.; Divella, C.; Loverre, A.; Stasi, A.; Curci, C.; Rossini, M.; Ditonno, P.; Battaglia, M.; Daha, M.R.; Kooten, C. van; Gesualdo, L.; Schena, F.P. & Grandaliano, G. (2012), Complement (C) Activation in Renal Ischemia/Reperfusion (I/R) Injury Is Mediated by Pentraxin 3 (PTX3): A Species-Specific Effect, American Journal of Transplantation 12: 218-218.
- Pol, P. van der; Vries, D.K. de; Gijlswijk, D.J. van; Anken, G.E. van; Schlagwein, N.; Daha, M.R.; Aydin, Z.; Fijter, J.W. de; Schaapherder, A.F.M. & Kooten, C. van (2012), Pitfalls in urinary complement measurements, Transplant Immunology 27(1): 55-58.
- Aydin, Z.; Mallat, M.J.K.; Schaapherder, A.F.M.; Zonneveld, A.J. van; Kooten, C. van; Rabelink, T.J. & Fijter, J.W. de (2012), Randomized Trial of Short-Course High-Dose Erythropoietin in Donation After Cardiac Death Kidney Transplant Recipients, American Journal of Transplantation 12(7): 1793-1800.
- Eikmans, M.; Canck, I. de; Pol, P. van der; Baan, C.C.; Haasnoot, G.W.; Mallat, M.J.K.; Bryson-Vergunst, M.; Meester, E. de; Roodnat, J.I.; Anholts, J.D.H.; Thielen, M. van; Doxiadis, I.I.N.; Fijter, H.W. de; Linden, P.J.E. van der; Beelen, E. van; Kooten, C. van; Kal-van Gestel, J.A.; Peeters, A.M.A.; Weimar, W.; Roelen, D.L.; Rossau, R. & Claas, F.H.J. (2011), A FUNCTIONAL POLYMORPHISM IN FICOLIN-2 IN THE DONOR KIDNEY IS ASSOCIATED WITH IMPROVED RENAL TRANSPLANT OUTCOME., Human Immunology 72: S191-S191.
- Amir, A.L.; Steen, D.M. van der; Loenen, M.M. van; Hagedoorn, R.S.; Boer, R. de; Kester, M.D.G.; Ru, A.H. de; Lugthart, G.J.; Kooten, C. van; Hiemstra, P.S.; Jedema, I.; Griffioen, M.; Veelen, P.A. van; Falkenburg, J.H.F. & Heemskerk, M.H.M. (2011), PRAME-Specific Allo-HLA-Restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-Cell Receptor Gene Transfer, Clinical Cancer Research 17(17): 5615-5625.
- Pol, P. van der; Vries, D.K. de; Gijlswijk, D.J. van; Anken, G.E. van; Roos, A.; Aydin, Z.; Johan, J.W. de; Schaapherder, A.F.M. & Kooten, C. van (2011), Misinterpretation of complement activation in urine, Molecular Immunology 48(14): 1727-1727.
- Pol, P. van der; Roos, A.; Berger, S.P.; Bajema, I.M.; Stahl, G.L.; Schlagwein, N.; Gijlswijk, D.J. van; Daha, M.R. & Kooten, C. van (2011), Mannose-binding lectin induces tubular epithelial cell death following renal ischemia reperfusion injury independent of complement activation, Molecular Immunology 48(14): 1679-1679.
- Schonkeren, D.; Hoorn, M.L. van der; Khedoe, P.; Swings, G.; Beelen, E. van; Claas, F.; Kooten, C. van; Heer, E. de & Scherjon, S. (2011), Differential Distribution and Phenotype of Decidual Macrophages in Preeclamptic versus Control Pregnancies, American Journal of Pathology 178(2): 709-717.
- Botermans, J.M.; Kort, H. de; Eikmans, M.; Koop, K.; Baelde, H.J.; Mallat, M.J.K.; Zuidwijk, K.; Kooten, C. van; Heer, E. de; Goemaere, N.N.T.; Claas, F.H.J.; Bruijn, J.A.; Fijter, J.W. de; Bajema, I.M. & Groningen, M.C. van (2011), C4d Staining In Renal Allograft Biopsies with Early Acute Rejection and Subsequent Clinical Outcome, Clinical Journal of the American Society of Nephrology 6(5): 1207-1213.
- D'Orsogna, L.J.A.; Roelen, D.L.; Meer-Prins, E.M.W. van der; Pol, P. van der; Franke-van Dijk, M.E.; Eikmans, M.; Anholts, J.; Rossjohn, J.; McCluskey, J.; Mulder, A.; Kooten, C. van; Doxiadis, I.I.N. & Claas, F.H.J. (2011), Tissue Specificity of Cross-Reactive Allogeneic Responses by EBV EBNA3A-Specific Memory T Cells, Transplantation 91(5): 494-500.
- Meer-Prins, E.M.W. van der; Besouw, N.M. van; D'Orsogna, L.J.A.; Pol, P. van der; Franke-van Dijk, M.; Zoet, Y.M.; Slik, A. van der; Weimar, W.; Kooten, C. van; Mulder, A.; Roelen, D.L.; Doxiadis, I.I.N. & Claas, F.H.J. (2011), Vaccine induced Allo-HLA reactive memory T-cells in a kidney transplantation candidate, Tissue Antigens 77(5): 389-390.
- Balu, S.; Reljic, R.; Lewis, M.J.; Pleass, R.J.; McIntosh, R.; Kooten, C. van; Egmond, M. van; Challacombe, S.; Woof, J.M. & Ivanyi, J. (2011), A Novel Human IgA Monoclonal Antibody Protects against Tuberculosis, Journal of Immunology 186(5): 3113-3119.
- Eikmans, M.; Canck, I. de; Pol, P. van der; Baan, C.C.; Haasnoot, G.W.; Mallat, M.J.K.; Bryson-Vergunst, M.; Meester, E. de; Roodnat, J.I.; Anholts, J.D.H.; Thielen, M. van; Doxiadis, I.I.N.; Fijter, H.W. de; Linden, P.J.E. van der; Beelen, E. van; Kooten, C. van; Kal-van Gestel, J.; Peeters, A.M.A.; Weimar, W.; Roelen, D.L.; Rossau, R. & Claas, F.H.J. (2011), A functional polymorphism in Ficolin-2 in the donor kidney is associated with improved renal transplant outcome, Tissue Antigens 77(5): 384-384.
- D'Orsogna, L.J.A.; Roelen, D.L.; Meer-Prins, E.M.W. van der; Besouw, N.M. van; Pol, P. van der; Franke-van Dijk, M.; Zoet, Y.M.; Slik, A. van der; Weimar, W.; Kooten, C. van; Doxiadis, I.I.N. & Claas, F.H.J. (2011), VACCINE INDUCED ALLO-HLA REACTIVE MEMORY T-CELLS IN A KIDNEY TRANSPLANTATION CANDIDATE, Human Immunology 72: S60-S60.
- Kort, H. de; Crul, C.; Wal, A.M. van der; Schlagwein, N.; Stax, A.M.; Bajema, I.M.; Bruijn, J.A.; Kooten, C. van & Heer, E. de (2011), PRE-TREATMENT WITH DONOR TOLEROGENIC DENDRITIC CELLS RESULTS IN ANTIBODY-MEDIATED, ACCELERATED GRAFT LOSS OF RODENT PANCREATIC ISLETS.
- O'Flynn, J.; Flierman, R.; Pol, P. van der; Rops, A.; Satchell, S.C.; Mathieson, P.W.; Kooten, C. van; Vlag, J. van der; Berden, J.H. & Daha, M.R. (2011), Nucleosomes and C1q bound to glomerular endothelial cells serve as targets for autoantibodies and determine complement activation, Molecular Immunology 49(1-2): 75-83.
- Kraaij, M.D.; Kooij, S.W. van der; Reinders, M.E.J.; Koekkoek, K.; Rabelink, T.J.; Kooten, C. van & Gelderman, K.A. (2011), Dexamethasone increases ROS production and T cell suppressive capacity by anti-inflammatory macrophages, Molecular Immunology 49(3): 549-557.
- D'Orsogna, L.J.A.; Besouw, N.M. van; Meer-Prins, E.M.W. van der; Pol, P. van der; Franke-van Dijk, M.; Zoet, Y.M.; Slik, A. van der; Weimar, W.; Kooten, C. van; Mulder, A.; Roelen, D.L.; Doxiadis, I.I.N. & Claas, F.H.J. (2011), Vaccine-Induced Allo-HLA-Reactive Memory T Cells in a Kidney Transplantation Candidate, Transplantation 91(6): 645-651.
- Flynn, J.O.; Flierman, R.; Pol, P. van der; Rops, A.; Satchell, S.; Mathieson, P.; Kooten, C. van; Vlag, J. van der; Berden, J. & Daha, M. (2011), Both nucleosomes and C1q bind to glomerular endothelial cells in vitro, serve as targets for autoantibodies and determine complement activation, Molecular Immunology 48(14): 1727-1728.
- Pol, P. van der; Roos, A.; Berger, S.P.; Daha, M.R. & Kooten, C. van (2011), Natural IgM antibodies are involved in the activation of complement by hypoxic human tubular cells, AJP - Renal Physiology 300(4): F932-F940.
- Kooten, C. van; Lombardi, G.; Gelderman, K.A.; Sagoo, P.; Buckland, M.; Lechler, R. & Cuturi, M.C. (2011), Dendritic Cells as a Tool to Induce Transplantation Tolerance: Obstacles and Opportunities, Transplantation 91(1): 2-7.
- Kraaij, M.D.; Savage, N.D.L.; Kooij, S.W. van der; Koekkoek, K.; Wang, J.; Berg, J.M. van den; Ottenhoff, T.H.M.; Kuijpers, T.W.; Holmdahl, R.; Kooten, C. van & Gelderman, K.A. (2010), Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species, Proceedings of the National Academy of Sciences 107(41): 17686-17691.
- Kort, H. de; Munivenkatappa, R.B.; Berger, S.P.; Eikmans, M.; Wal, A. van der; Koning, E.J. de; Kooten, C. van; Heer, E. de; Barth, R.N.; Bruijn, J.A.; Philosophe, B.; Drachenberg, C.B. & Bajema, I.M. (2010), Pancreas Allograft Biopsies with Positive C4d Staining and Anti-Donor Antibodies Related to Worse Outcome for Patients, American Journal of Transplantation 10(7): 1660-1667.
- Rekers, N.V.; Bajema, I.M.; Mallat, M.; Zuidwijk, K.; Anholts, J.D.H.; Goemaere, N.; Groningen, M.C. van; Kooten, C. van; Fijter, J.W. de; Claas, F.H.J. & Eikmans, M. (2010), Quantitative PCR profiling of kidney transplant patients for prediction of response to anti-rejection treatment with steroids, Tissue Antigens 75(5): 595-595.
- D'Orsogna, L.; Meer-Prins, E. van der; Pol, P. van der; Franke-van Dijk, M.; Zoet, Y.; Eikmans, M.; Anholts, J.; Mulder, A.; Kooten, C. van; Rossjohn, J.; McCluskey, J.; Roelen, D.; Doxiadis, I. & Claas, F. (2010), Organ specificity of cross-reactive allogeneic responses by viral specific memory T-cells, Tissue Antigens 75(5): 467-467.
- Borcherding, F.; Nitschke, M.; Hundorfean, G.; Rupp, J.; Smolinski, D. von; Bieber, K.; Kooten, C. van; Lehnert, H.; Fellermann, K. & Buning, J. (2010), The CD40-CD40L Pathway Contributes to the Proinflammatory Function of Intestinal Epithelial Cells in Inflammatory Bowel Disease, American Journal of Pathology 176(4): 1816-1827.
- D'Orsogna, L.; Meer-Prins, E. van der; Pol, P. van der; Franke-van Dijk, M.; Zoet, Y.; Eikmans, M.; Anholts, J.; Mulder, A.; Kooten, C. van; Rossjohn, J.; McCluskey, J.; Roelen, D.; Doxiadis, I. & Claas, F. (2010), ORGAN SPECIFIFITY OF CROSS-REACTIVE ALLOGENEIC RESPONSES BY VIRAL SPECIFIC MEMORY T-CELLS., Human Immunology 71: S69S69.
- Pol, P. van der; Roos, A.; Berger, S.P.; Bajema, I.M.; Stahl, G.L.; Gijlswijk, D.J.; Schlagwein, N.; Daha, M.R. & Kooten, C. van (2010), Inhibition of mannose-binding lectin preserves renal function in a rat model of renal ischemia reperfusion injury, Molecular Immunology 47(13): 2201-2202.
- Castellano, G.; Trouw, L.A.; Fiore, N.; Daha, M.R.; Schena, F.P. & Kooten, C. van (2010), Infiltrating dendritic cells contribute to local synthesis of C1q in murine and human lupus nephritis, Molecular Immunology 47(11-12): 2129-2137.
- Vuong, M.T.; Hahn-Zoric, M.; Lundberg, S.; Gunnarsson, I.; Kooten, C. van; Wramner, L.; Seddighzadeh, M.; Fernstrom, A.; Hanson, L.A.; Lieu, T.D.; Jacobson, S.H. & Padyukov, L. (2010), Association of soluble CD89 levels with disease progression but not susceptibility in IgA nephropathy, Kidney International 78(12): 1281-1287.
- Gelderman, K.A.; Kraaij, M.D.; Kooij, S.W. van der; Koekkoek, K.; Wang, J.; Holmdahl, R. & Kooten, C. van (2010), Anti-inflammatory macrophages induce regulatory T cells by producing reactive oxygen species, European Journal of Clinical Investigation 40: 27-27.
- Laar, L. van de; Bosch, A. van den; Kooij, S.W. van der; Janssen, H.L.A.; Coffer, P.J.; Kooten, C. van & Woltman, A.M. (2010), A Nonredundant Role for Canonical NF-kappa B in Human Myeloid Dendritic Cell Development and Function, Journal of Immunology 185(12): 7252-7261.
- Rekers, N.V.; Bajema, I.M.; Zuidwijk, K.; Mallat, M.J.; Goemaere, N.; Groningen, M.C. van; Kooten, C. van; Fijter, H.W. de; Claas, F.H. & Eikmans, M. (2009), Intragraft expression profiles by quantitative PCR in kidney transplant patients reflect variability in the response to anti-rejection treatment with corticosteroids, Tissue Antigens 73(5): 389-389.
- Heidt, S.; Roelen, D.L.; Kooten, C. van; Eijsink, C.; Claas, F. & Mulder, A. (2009), THE EFFECTS OF IMMUNOSUPPRESSIVE DRUGS ON T CELL DEPENDENT B CELL CULTURES, Human Immunology 70: S74S74.
- Heidt S, Roelen DL, van Kooten C, Eijsink C, Claas FHJ & Mulder A (2009), The effects of immunosuppressive drugs on T cell dependent B cell cultures, Tissue Antigens 73(5): 390-390.
- van Kooten C, Kraaij MD, van der Kooij SW, Koekkoek K & Gelderman KA (2009), Anti-Inflammatory Macrophages Suppress Allospecific T Cell Responses and Induce Treg Via Reactive Oxygen Species (ROS) Production., American Journal of Transplantation 9: 300-300.
- Flierman R, Faber-Krol RMC, Satchell SC, Mathieson PW, van Kooten C, van der Vlag J, Berden J & Daha MR (2009), Immune complex bound C1q enhances complement activation on glomerular endothelial cells, Molecular Immunology 46(14): 2827-2827.
- van der Pol P, Roos A, Berger SP, van Kooten C, Mathieson PW, Satchell SC & Daha MR (2009), Hypoxia induces complement activation on HUMAN kidney proximal tubular epithelial cells via the classical pathway, Molecular Immunology 46(14): 2832-2832.
- Jennings P, Aydin S, Bennett J, McBride R, Weiland C, Tuite N, Gruber LN, Perco P, Gaora PO & Ellinger-Ziegelbauer H (2009), Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion, Toxicology in Vitro 23(3): 486-499.
- Otten MA, Groeneveld TWL, Flierman R, Rastaldi MP, Trouw LA, Faber-Krol MC, Visser A, Essers MC, Claassens J & Verbeek JS (2009), Both Complement and IgG Fc Receptors Are Required for Development of Attenuated Antiglomerular Basement Membrane Nephritis in Mice, Journal of Immunology 183(6): 3980-3988.
- Velthuis JH, Unger WW, van der Slik AR, Duinkerken G, Engelse M, Schaapherder AF, Ringers J, van Kooten C, de Koning EJ & Roep BO (2009), Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreas allograft of a type 1 diabetic recipient, Diabetologia 52(3): 494-503.
- Zuidwijk K, de Fijter JW, Mallat MJK, Eikmans M, Bajema I & van Kooten C (2009), Increased Numbers of Myeloid and Plasmacytoid Dendritic Cells during Human Renal Allograft Rejection Are Accompanied by Local Maturation., American Journal of Transplantation 9: 554-554.
- Spirig R, van Kooten C, Obregon C, Nicod L, Daha M & Rieben R (2008), The complement inhibitor low molecular weight dextran sulfate prevents TLR4-induced phenotypic and functional maturation of human dendritic cells, Journal of Immunology 181(2).
- Heidt S, Roelen DL, van Kooten C, Eijsink C, Claas FHJ & Mulder A (2008), The effects of immunosuppressive drugs on in vitro stimulated B cells, American Journal of Transplantation 8.
- Stax AM, Crul C, Kamerling SWA, Schlagwein N, van der Geest RN, Woltman AM & van Kooten C (2008), CD40L stimulation of rat dendritic cells specifically favors the IL-12/IL-10 ratio resulting in a strong T cell stimulatory capacity, Molecular Immunology 45(9).
- Oortwijn BD, Eijgenroom OW, Rastoldi MP, Roos A, Doha MR & van Kooten C (2008), The role of secretory IgA and complement in IgA nephropathy, Seminars in Nephrology 28(1).
- Stax AM, Gelderman KA, Kamerling SWA, van der Geest R, Schlagwein N & van Kooten C (2008), Generation and characterization of a novel anti-rat CD40L antibody with inhibitory activities in vitro and in vivo, Journal of Immunological Methods 335(1-2).
- Stax AM, Gelderman KA, Schlagwein N, Essers MC, Kamerling SWA, Woltman AM & van Kooten C (2008), Induction of Donor-Specific T-Cell Hyporesponsiveness Using Dexamethasone-Treated Dendritic Cells in Two Fully Mismatched Rat Kidney Transplantation Models, Transplantation 86(9).
- Eijgenraam JW, Oortwijn BD, Kamerling SWA, de Fijter JW, Bake AWLV, Daha MR & van Kooten C (2008), Secretory immunoglobulin A (IgA) responses in IgA nephropathy patients after mucosal immunization, as part of a polymeric IgA response, Clinical and Experimental Immunology 152(2).
- Eijgenraam JW & van Kooten C (2008), IgA1 glycosylation in IgA nephropathy: As sweet as it can be, Kidney International 73(10).
- Xu W, Berger SP, Trouw LA, de Boer HC, Schlagwein N, Mutsaers C, Daha MR & van Kooten C (2008), Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation, Journal of Immunology 180(11).
- Eikmans M, Roelen DL, van Kooten C, de Fijter HW & Claas FHJ (2008), Increased mRNA expression of transforming growth factor-beta and FoxP3 in urine from renal allograft recipients is associated with occurrence of graft rejection, American Journal of Transplantation 8.
- Heidt S, Roelen DL, Eijsink C, van Kooten C, Claas FHJ & Mulder A (2008), Effects of Immunosuppressive Drugs On Purified Human B Cells: Evidence Supporting the Use of MMF and Rapamycin, Transplantation 86(9).
- Eijgenraam JW, Reinartz SM, Kamerling SWA, Van Ham VJ, Zuidwijk K, van Drunen CM, Daha MR, Fokkens WJ & van Kooten C (2008), Immuno-histological analysis of dendritic cells in nasal biopsies of IgA nephropathy patients, Nephrology Dialysis Transplantation 23(2).
- Xu W, Berger S, Trouw L, de Boer H, Schlagwein N, Mutsaers C, Daha M & van Kooten C (2008), Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation, Molecular Immunology 45(16).
- van Kooten C, Fiore N, Trouw LA, Csomor E, Xu W, Castellano G, Daha MR & Gelderman KA (2008), Complement production and regulation by dendritic cells: Molecular switches between tolerance and immunity, Molecular Immunology 45(16).
- Eikmans M, Nacken W, Bajema IM, Zuidwijk K, Roos-van Groningen MC, van Kooten C, de Fijter JW, Bruijn JA, Roth J & Claas FHJ (2008), Presence of macrophage-expressed S100 calcium binding proteins AS and A9 during transplant rejection is associated with expression of IL-4, IL-10, and TGF-beta, Tissue Antigens 71(4).
- Heidt S, Roelen DL, Kooten C, Eijsink C, Claas F & Mulder A (2008), The effects of immunosuppressive drugs on in vitro stimulated B cells, Tissue Antigens 71(4).
- Gaarkeuken H, Siezenga MA, Zuidwijk K, van Kooten C, Rabelink TJ, Daha MR & Berger SP (2008), Complement activation by tubular cells is mediated by properdin binding, AJP - Renal Physiology 295(5).
- Berger SP, Roos A, Mallat MJK, Schaapherder AFM, Doxiadis II, van Kooten C, Dekker FW, Daha MR & de Fijter JW (2007), Low pretransplantation mannose-binding lectin levels predict superior patient and graft survival after simultaneous pancreas-kidney transplantation, Journal of the American Society of Nephrology 18(8).
- Berger SP, Roos A, Mallat MJK, Schaapherder AF, Doxiadis II, van Kooten C, Daha MR & de Fijter JW (2007), Low mannose-binding lectin levels are associated with superior graft and patient survival after simultaneous pancreas-kidney transplantation., American Journal of Transplantation 7.
- Spirig R, van Kooten C, Obregon C, Nicod L, Daha M & Rieben R (2007), Inhibition of toll-like receptor induced phenotypic and functional maturation of human dendritic cells by the complement inhibitor low molecular weight dextran sulfate, Molecular Immunology 44(1-3).
- Montfoort, N. van; Jong, J.M.H. de; Schuurhuis, D.H.; Voort, E.I.H. van der; Camps, M.G.M.; Huizinga, T.W.J.; Kooten, C. van; Daha, M.R.; Verbeek, J.S.; Ossendorp, F. & Toes, R.E.M. (2007), A novel role of complement factor C1q in augmenting the presentation of antigen captured in immune complexes to CD8+T lymphocytes, Journal of Immunology 178(12).
- Hahn-Zoric M, Tahmasebifar N, van Kooten C, Ahlmen J, Swerkersson S, Hansson S, Berg U, Hanson LA, Padyukov L & Jacobson SH (2007), Immunoassays for detection of soluble fc alpha receptor (CD89) in plasma of IgA nephropathy patients, Clinical Immunology 123.
- Castellano G, Woltman AM, Schlagwein N, Xu W, Schena FP, Daha MR & van Kooten C (2007), Immune modulation of human dendritic cells by complement, European Journal of Immunology 37(10).
- Oortwijn BD, Rastaldi MP, Roos A, Mattinzoli D, Daha MR & van Kooten C (2007), Demonstration of secretory IgA in kidneys of patients with IgA nephropathy, Nephrology Dialysis Transplantation 22(11).
- Spirig R, van Kooten C, Obregon C, Nicod L, Daha M & Rieben R (2007), Modulation of toll-like receptor mediated maturation of professional human antigen-presenting cells by the complement inhibitor low molecular weight dextran sulfate, Molecular Immunology 44(16).
- Woltman AM, de Fijter JW, Zuidwijk K, Vlug AG, Bajema IM, van der Kooij SW, van Ham V & van Kooten C (2007), Quantification of dendritic cell subsets in human renal tissue under normal and pathological conditions, Kidney International 71(10).
- Spirig R, Van Kooten C, Obregon C, Nicod L, Daha M & Rieben R (2007), Low molecular weight dextran sulfate modulates Toll-like receptor induced human dendritic cell activation, Swiss Medical Weekly 137.
- Heidt S, Roelen DL, van Kooten C, Eijsink C, Claas FHJ & Mulder A (2007), The effects of immunosuppressive drugs on in vitro stimulated B cells, Tissue Antigens 69(5).
- Xu W, Schlagwein N, Roos A, van den Berg TK, Daha MR & van Kooten C (2007), Human peritoneal macrophage show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages, European Journal of Immunology 37(6).
- Xu W, Roos A, Schlagwein N, Thijssen P, Daha MR & van Kooten C (2007), Regulatory role of C1q in the inflammatory status of macrophages, Molecular Immunology 44(1-3).
- Oortwijn BD, Roos A, Van der Boog PJM, Klar-Mohamad N, van Remoortere A, Deelder AM, Daha MR & van Kooten C (2007), Monomeric and polymeric IgA show a similar association with the myeloid Fc alpha RI/CD89, Molecular Immunology 44(5).
- van Sorge NM, Yuki N, Koga M, Susuki K, Jansen MD, van Kooten C, van de Winkel JGJ, van der Pol WL & van den Berg LH (2007), Ganglioside-specific IgG and IgA recruit leukocyte effector functions in Guillain-Barre syndrome, Journal of Neuroimmunology 182(1-2).
- Roos A & van Kooten C (2007), Underglycosylation of IgA in IgA nephropathy: More than a diagnostic marker?, Kidney International 71(11).
- Woltman AM, van der Kooij SW, de Fijter JW & van Kooten C (2006), Maturation-resistant dendritic cells induce hyporesponsiveness in alloreactive CD45RA(+) and CD45RO(+) T-cell populations, American Journal of Transplantation 6(11).
- Xu W, Roos A, Schlagwein N, Woltman AM, Daha MR & van Kooten C (2006), IL-10-producing macrophages preferentially clear early apoptotic cells, Blood 107(12).
- Xu W, Roos A, Daha MR & van Kooten C (2006), Dendritic cell and macrophage subsets in the handling of dying cells, Immunobiology 211(6-8).
- Berthier CC, Lods N, Joosten SA, van Kooten C, Leppert D, Lindberg RLP, Kappeler A, Raulf F, Sterchi EE, Lottaz D & Marti HP (2006), Differential regulation of metzincins in experimental chronic renal allograft rejection: Potential markers and novel therapeutic targets, Kidney International 69(2).
- Oortwijn BD, Roos A, Royle L, van Gijlswijk-Janssen DJ, Faber-Krol MC, Eijgenraam JW, Dwek RA, Daha MR, Rudd PM & van Kooten C (2006), Differential glycosylation of polymeric and monomeric IgA: A possible role in glomerular inflammation in IgA nephropathy, Journal of the American Society of Nephrology 17(12).
- Oortwijn BD, van der Boog PJM, Roos A, van der Geest RN, de Fijter JW, Daha MR & van Kooten C (2006), A pathogenic role for secretory IgA in IgA nephropathy, Kidney International 69(7).
- Polderman MCA, van Kooten C, Smit NPM, Kamerling SWA & Pavel S (2006), Ultraviolet-A (UVA-1) radiation suppresses immunoglobulin production of activated B lymphocytes in vitro, Clinical and Experimental Immunology 145(3).
- Roos A, Rastaldi MP, Calvaresi N, Oortwijn BD, Schlagwein N, van Gijlswijk-Janssen DJ, Stahl GL, Matsushita M, Fujita T, van Kooten C & Daha MR (2006), Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease, Journal of the American Society of Nephrology 17(6).
- Mulder A, Eijsink C, Kardol MJ, Franke MEI, Kesler M, van Kooten C, Doxiadis IN & Claas FHJ (2005), Dissection of the humoral response against HLA-A2 by molecular analysis of antibodies produced by single B-CELLS., American Journal of Transplantation 5.
- Joosten SA & van Kooten C (2005), Non-HLA humoral immunity and chronic kidney-graft loss, Lancet 365(9470).
- Joosten SA, Sijpkens YWJ, van Ham V, Trouw LA, van der Vlag J, van den Heuvel B, van Kooten C & Paul LC (2005), Antibody response against the glomerular basement membrane protein agrin in patients with transplant glomerulopathy, American Journal of Transplantation 5(2).
- Mulder A, Eijsink C, Franke M, Kester M, van Kooten C, Doxiadis I & Claas F (2005), Dissection of the humoral response against HLA-A2 by molecular analysis of antibodies produced by single B-cells, Genes and Immunity 6.
- Koch M, Joosten SA, Mengel M, van Kooten C, Paul LC & Nashan B (2005), Adoptive transfer of primed CD4+T-lymphocytes induces pattern of chronic allograft nephropathy in a nude rat model, Transplantation 79(7).
- Woltman AM, de Fijter JW, van der Kooij SW, Jie KE, Massacrier C, Caux C, Daha MR & van Kooten C (2005), MIP-3 alpha/CCL20 in renal transplantation and its possible involvement as dendritic cell chemoattractant in allograft rejection, American Journal of Transplantation 5(9).
- Trouw LA, Seelen MA, Duijs JMGJ, Wagner S, Loos M, Bajema IM, van Kooten C, Roos A & Daha MR (2005), Activation of the lectin pathway in murine lupus nephritis, Molecular Immunology 42(6).
- de Haij S, Woltman AM, Trouw LA, Bakker AC, Kamerling SW, van der Kooij SW, Chen LP, Kroczek RA, Daha MR & van Kooten C (2005), Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1, Kidney International 68(5).
- de Haij S, Bakker AC, van der Geest RN, Haegeman G, Vanden Berghe W, Aarbiou J, Daha MR & van Kooten C (2005), NF-kappa B mediated IL-6 production by renal epithelial cells is regulated by C-Jun NH2-terminal kinase, Journal of the American Society of Nephrology 16(6).
- Mulder A, Eijsink C, Kester MGD, Franke MEI, Kardol MJ, Heemskerk MHM, van Kooten C, Verreck FA, Drijfhout JW, Koning F, Doxiadis IIN & Claas FHJ (2005), Impact of peptides on the recognition of HLA class I molecules by human HLA antibodies, Journal of Immunology 175(9).
- Eijgenraam JW, Woltman AM, Kamerling SWA, Briere F, de Fijter JW, Daha MR & van Kooten C (2005), Dendritic cells of IgA nephropathy patients have an impaired capacity to induce IgA production in naive B cells, Kidney International 68(4).
- Joosten SA, Sijpkens YWJ, van Kooten C & Paul LC (2005), Chronic renal allograft rejection: Pathophysiologic considerations, Kidney International 68(1).
- van der Boog PJM, van Kooten C, de Futer JW & Daha MR (2005), Role of macromolecular IgA in IgA nephropathy, Kidney International 67(3).
- van Kooten C & Woltman AM (2005), CD40 brings the shuttle down, Blood 106(6).
- Joosten SA, van Dixhoorn MGAS, Borrias MC, van Ham V, Koerkamp MJAG, Savolainen-Peltonen HM, Hayry P, Daha MR, van Kooten C & Paul LC (2005), Genetic profiling of aortic allografts: prothymosin alpha as potential target?, Transplant International 18(8).
- Joosten SA, van Ham V, Borrias MC, van Kooten C & Paul LC (2005), Antibodies against mesangial cells in a rat model of chronic renal allograft rejection, Nephrology Dialysis Transplantation 20(4).
- Nauta AJ, de Haij S, Bottazzi B, Mantovani A, Borrias MC, Aten J, Rastaldi MP, Daha MR, van Kooten C & Roos A (2005), Human renal epithelial cells produce the long pentraxin PTX3, Kidney International 67(2).
- Castellano G, Woltman AM, Nauta AJ, Roos A, Trouw LA, Seelen MA, Schena FP, Daha MR & van Kooten C (2004), Maturation of dendritic cells abrogates C1q production in vivo and in vitro, Blood 103(10).
- Joosten SA, van Kooten C, Sijpkens YWJ, de Fijter JW & Paul LC (2004), The pathobiology of chronic allograft nephropathy: Immune-mediated damage and accelerated aging, Kidney International 65(5).
- Joosten SA, Benediktsson H, Borrias MC, Van Ham V, Van Dixhoorn MGA, Van Kooten C & Paul LC (2004), Anti-tubular basement membrane antibodies and giant cell formation in a model of chronic renal allograft rejection, Transplantation 77(8).
- Lam S, van der Geest RN, Verhagen NAM, Daha MR & van Kooten C (2004), Secretion of collagen type IV by human renal fibroblasts is increased by high glucose via a TGF-beta-independent pathway, Nephrology Dialysis Transplantation 19(7).
- van der Boog PJM, van Kooten C, van Zandbergen G, Klar-Mohamad N, Oortwijn B, Bos NA, van Remoortere A, Hokke CH, de Fijter JW & Daha MR (2004), Injection of recombinant Fc alpha RI/CD89 in mice does not induce mesangial IgA deposition, Nephrology Dialysis Transplantation 19(11).
- van Kooten C (2004), Dectin-1: unique appetite for yeast, Blood 104(13).
- Roos A, Xu W, Castellano G, Nauta AJ, Garred P, Daha MR & van Kooten C (2004), A pivotal role for innate immunity in the clearance of apoptotic cells, European Journal of Immunology 34(4).
- Trouw LA, Groeneveld TWL, Seelen MA, Duijs JMGJ, Bajema IM, Prins FA, Kishore U, Salant DJ, Verbeek JS, van Kooten C & Daha MR (2004), Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes, Journal of Clinical Investigation 114(5).
- Woltman AM, Schlagwein N, van der Kooij SW & van Kooten C (2004), The novel cyclophilin-binding drug sanglifehrin A specifically affects antigen uptake receptor expression and endocytic capacity of human dendritic cells, Journal of Immunology 172(10).
- Nauta AJ, Castellano G, Xu W, Woltman AM, Borrias MC, Daha MR, van Kooten C & Roos A (2004), Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells, Journal of Immunology 173(5).
- Castellano G, Woltman AM, Schena FP, Roos A, Daha MR & van Kooten C (2004), Dendritic cells and complement: at the cross road of innate and adaptive immunity, Molecular Immunology 41(2-3).
- de Haij S, Daha MR & van Kooten C (2004), Mechanism of steroid action in renal epithelial cells, Kidney International 65(5).
- Trouw LA, Seelen MA, Visseren R, Duijs JMGJ, Benediktsson H, De Heer E, Roos A, Van Kooten C & Daha MR (2004), Anti-C1q autoantibodies in murine lupus nephritis, Clinical and Experimental Immunology 135(1).
- Woltman AM & van Kooten C (2003), Functional modulation of dendritic cells to suppress adaptive immune responses, Journal of Leukocyte Biology 73(4).
- Nauta AJ, Daha MR, van Kooten C & Roos A (2003), Recognition and clearance of apoptotic cells: a role for complement and pentraxins, Trends in Immunology 24(3).
- Joosten SA, van Kooten C & Paul LC (2003), Pathogenesis of chronic allograft rejection, Transplant International 16(3).
- Lam S, van der Geest RN, Verhagen NAM, van Nieuwenhoven FA, Blom IE, Aten J, Goldschmeding R, Daha MR & van Kooten C (2003), Connective tissue growth factor and IGF-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose, Diabetes 52(12).
- de Haij S, Adcock IM, Bakker AC, Gobin SJP, Daha MR & van Kooten C (2003), Steroid responsiveness of renal epithelial cells - Dissociation of transrepression and transactivation, Journal of Biological Chemistry 278(7).
- Lam S, Verhagen NAM, Strutz F, Van Der Pijl JW, Daha MR & Van Kooten C (2003), Glucose-induced fibronectin and collagen type III expression in renal fibroblasts can occur independent of TGF-beta 1, Kidney International 63(3).
- Woltman AM, van der Kooij SW, Coffer PJ, Offringa R, Daha MR & van Kooten C (2003), Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27(KIP1) expression, Blood 101(4).
- van der Boog PJM, de Fijter JW, van Kooten C, van der Holst R, van Seggelen A, van Es LA & Daha MR (2003), Complexes of IgA with Fc alpha RI/CD89 are not specific for primary IgA nephropathy, Kidney International 63(2).
- Joosten SA, van Ham V, Nolan CE, Borrias MC, Jardine AG, Shiels PG, van Kooten C & Paul LC (2003), Telomere shortening and cellular senescence in a model of chronic renal allograft rejection, American Journal of Pathology 162(4).
- Heystek HC, Moulon C, Woltman AM, Garonne P & van Kooten C (2002), Human immature dendritic cells efficiently bind and take up secretory IgA without the induction of maturation, Journal of Immunology 168(1).
- Joosten SA, van Dixhoorn MGA, Borrias MC, Benediktsson H, van Veelen PA, van Kooten C & Paul LC (2002), Antibody response against perlecan and collagen types IV and VI in chronic renal allograft rejection in the rat, American Journal of Pathology 160(4).
- van Esch WJE, Reparon-Schuijt CC, Hamstra HJ, van Kooten C, Logtenberg T, Breedveld FC & Verweij CL (2002), Polyreactivity of human IgG Fc-binding phage antibodies constructed from synovial fluid CD38+B cells of patients with rheumatoid arthritis, Journal of Autoimmunity 19(4).
- de Haij S, Woltman AM, Bakker AC, Daha MR & van Kooten C (2002), Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids, British Journal of Pharmacology 137(2).
- Bakker RC, van Kooten C, van de Lagemaat-Paape ME, Daha MR & Paul LC (2002), Renal tubular epithelial cell death and cyclosporin A, Nephrology Dialysis Transplantation 17(7).
- Woltman AM, Massacrier C, de Fijter JW, Caux C & van Kooten C (2002), Corticosteroids prevent generation of CD34(+)-derived dermal dendritic cells but do not inhibit langerhans cell development, Journal of Immunology 168(12).
- Woltman AM, de Fijter JW, Kamerling SWA, van der Kooij SW, Paul LC, Daha MR & van Kooten C (2001), Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages, Blood 98(1).
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Schellekens GA, de Jong BAW, van Venrooij WJ, Breedveld FC & Verweij CL (2001), Secretion of anti-citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis, Arthritis and Rheumatism 44(1).
- Strutz F, Zeisberg M, Renziehausen A, Raschke B, Becker V, van Kooten C & Muller GA (2001), TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2), Kidney International 59(2).
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Ezendam NPM, Levarht EWN, Breedveld FC & Verweij CL (2001), Presence of a population of CD20+,CD38-B lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis, Arthritis and Rheumatism 44(9).
- Van Esch WJE, Reparon-Schuijt CC, Levarht EWN, Van Kooten C, Breedveld FC & Verweij CL (2001), Differential requirements for induction of total immunoglobulin and physiological rheumatoid factor production by human peripheral blood B cells, Clinical and Experimental Immunology 123(3).
- Weiler M, Kachko L, Chaimovitz C, Van Kooten C & Douvdevani A (2001), CD40 ligation enhances IL-15 production by tubular epithelial cells, Journal of the American Society of Nephrology 12(1).
- Daha MR & van Kooten C (2000), Is the proximal tubular cell a proinflammatory cell?, Nephrology Dialysis Transplantation 15.
- van Kooten C (2000), Immune regulation by CD40-CD40-L interactions - 2; Y2K update, Frontiers in Bioscience 5.
- van Kooten C & Banchereau J (2000), CD40-CD40 ligand.
- van Kooten C, Woltman AM & Daha MR (2000), Immunological function of tubular epithelial cells: The functional implications of CD40 expression.
- Woltman AM, De Haij S, Boonstra JG, Gobin SJP, Daha MR & Van Kooten C (2000), Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells, Journal of the American Society of Nephrology 11(11).
- Daha MR & van Kooten C (2000), Is there a role for locally produced complement in renal disease?, Nephrology Dialysis Transplantation 15(10).
- Woltman AM, de Fijter JW, Kamerling SWA, Paul LC, Daha MR & van Kooten C (2000), The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells.
- Reparon-Schuijt CC, van Esch WJE, van Kooten C, Rozier BCD, Levarht EWN, Breedveld FC & Verweij CL (2000), Regulation of synovial B cell survival in rheumatoid arthritis by vascular cell adhesion molecule 1 (CD106) expressed on fibroblast-like synoviocytes.
- Rea D, van Kooten C, van Meijgaarden KE, Ottenhoff THM, Melief CJM & Offringa R (2000), Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10.
- van Kooten C (1999), Blockade of costimulatory pathways of T-cell activation: the solution to acute and chronic rejection?