Biologics Formulation
Key publications
Key publications of the Biologics Formulation group
- Nejadnik M.R., Randolph T.W., Volkin D.B., Schöneich C., Carpenter J.F., Crommelin D.J.A. & Jiskoot W. (2018), Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues, Journal of Pharmaceutical Sciences107(8): 2013-2019.
- Varypataki E.M., Silva A.L., Barnier-Quer C., Collin N., Ossendorp F. & Jiskoot W. (2016), Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles., Journal of controlled release : official journal of the Controlled Release Society 226: 98-106.
- Silva, A.L., Rosalia, R., Sazak, A., Carstens, M.G., Ossendorp, F., Oostendorp, J., and Jiskoot, W. (2013) Optimization of encapsulation of a synthetic long peptide in PLGA nanoparticles: low burst release is crucial for efficient CD8+ T cell activation. Eur. J. Pharm. Biopharm. 83: 338-345.
- Filipe, V., Jiskoot, W., Basmeleh, A.H., Halim, A., Schellekens, H., and Brinks, V. (2012) Immunogenicity of different stressed IgG monoclonal antibody formulations in immune tolerant transgenic mice. mAbs 4: 740-752.
- Jiskoot, W., Randolph, T.W., Volkin, D.B., Middaugh, C.R., Schöneich, C., Winter, G., Friess, W., Crommelin, D.J.A., and John F. Carpenter, J.F. (2012) Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release. J. Pharm. Sci. 101: 946-954.