Conference
LED3 & LUCID Drug Discovery Meeting
- Date
- Thursday 6 February 2025
- Time
- Location
-
Poortgebouw
Rijnsburgerweg 10
2333 AA Leiden - Room
- Lecture Hall
Programme
| 08:30 - 09:00 | Registration and coffee |
| Chair: Gilles van Wezel | |
| 09:00 - 09:15 | Opening by Deans Jasper Knoester and Marlies Reinders |
|
Morning session: Early Drug Discovery and Development |
Chairs: Stephan Hacker & Marnix Medema |
|
09:15 - 09:35 |
Mario van der Stelt (Leiden University) Discovery of allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria |
|
09:40 - 10:00 |
Paul Jensen (UCSD, San Diego) Microbial natural product discovery: a molecule to microbes approach |
|
10:05 - 10:25 |
Joleen Masschelein (KU Leuven and VIB) Bacteria as tunable drug production factories |
| 10:30 - 10:50 |
Marnix Medema (Wageningen, NL) Omics-based prioritisation of natural product chemical space for drug discovery |
| 10:55 - 11:15 | Coffee break |
|
11:15 - 11:35 |
Gerard van Westen (Leiden University) AlphaFold Meets De Novo Drug Design - Structural Protein Information in Multitarget Molecular Generative Models |
|
11:40 - 12:00 |
Miquel Duran-Frigola (Ersilia Open Source Initiative, Barcelona) Open source AI/ML to fuel antimicrobial drug discovery research in Africa |
| 12:05 - 12:50 |
LED3 Keynote - Paola Picotti (ETH Zurich) Decoding the protein dance |
| 12:55 - 13:50 | Lunch |
| Afternoon session: Drug Discovery and Global Health | Chair: Anil Koul and Meta Roestenberg |
|
13:50 - 14:10 |
Gilles van Wezel (Leiden University) A pipeline for nonprofit drug discovery - from lab to international networks |
| 14:15 - 15:00 |
Keynote Kelly Chibale (University of Cape Town & H3D Foudation) Targeting kinases for malaria drug discovery |
| 15:05 - 15:25 | Coffee break |
|
15:20 - 15:40 |
Anil Koul (J&J) |
| 15:50 - 16:10 |
Susan Winks (H3D Drug Discovery and Development, Cape Town) Grand Challenges African Drug Discovery Accelerator (GC ADDA) network |
|
16:15 - 16:35 |
Moy Bracken (Access to Medicines Foundation) |
| 16:40 - 17:00 |
Alan Hennessy (GARDP, Geneva) Antibiotic Drug Discovery at GARDP |
| 17:05 - 17:25 |
Meta Roestenberg (LUMC, Leiden) Molecular design of a malaria vaccine |
| 17:30 - 18:45 | Drinks |
