Yi Ding
PhD candidate / guest
- Name
- Dr. Y. Ding
- Telephone
- +31 71 527 2727
- y.ding@biology.leidenuniv.nl
Yi Ding’s research focuses on understanding how transcriptomics and metabolomics are affected by an obese gene called leptin and mycobacterial infection which results in tuberculosis. For this, zebrafish, as an animal model, and multidisciplinary approaches from biology, chemistry and bioinformatics are used.
Publications
Ding, Y., Raterink, R., Marín-Juez, R. et al. Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae. Sci Rep 10, 11635 (2020). https://doi.org/10.1038/s41598-020-68443-y
PhD candidate / guest
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
Postdoc
- Science
- Instituut Biologie Leiden
- IBL Animal Sciences
- Singer R, Oganezova I., Hu W., Liu L., Ding Y., Groot H.J.M., Spaink H.P. & Alia A. (2024), Ultrahigh field diffusion magnetic resonance imaging uncovers intriguing microstructural changes in the adult zebrafish brain caused by Toll‐like receptor 2 genomic deletion, NMR in Biomedicine : e5170.
- Singer R., Oganezova I., Hu W., Ding Y., Papaioannou A., Groot H.J.M. de, Spaink H.P. & Alia A. (2024), Unveiling the exquisite microstructural details in Zebrafish brain non-invasively using magnetic resonance imaging at 28.2 T, Molecules 29(19): 4637.
- Hu W., Liu L., Forn-Cuní G., Ding Y., Alia A. & Spaink H.P. (2023), Transcriptomic and metabolomic studies reveal that toll-like receptor 2 has a role in glucose-related metabolism in unchallenged zebrafish larvae (Danio rerio), Biology 12(2): 323.
- Eeza M.N.H., Singer R., Ding Y., He J., Zuberi Z., Baelde H.J., Groot H.J.M. de, Matysik J., Spaink H.P. & Alia A. (2023), Probing microstructural changes in muscles of leptin-deficient zebrafish by non-invasive ex-vivo magnetic resonance microimaging, PLoS ONE 18(4): e0284215.
- Ding Y., Haks M.C., Eeden S.J.F. van den, Ottehoff T.H.M., Harms A.C., Hankemeier T., Eeza M.N.H., Matysik J., Alia A. & Spaink H.P. (2022), Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome, Metabolomics 18(8): 67.
- He J., Ding Y., Nowik N., Jager C., Eeza M.N.H., Alia A., Baelde H.J. & Spaink H.P. (2021), Leptin deficiency affects glucose homeostasis and results in adiposity in zebrafish, Journal of Endocrinology 249(2): 125-134.
- Ding Y., Haks M.C., Forn Cuní G., He J., Nowik N., Harms A.C., Hankemeier T., Eeza M.N.H., Matysik J., Alia A. & Spaink H.P. (2021), Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathways, Cell & Bioscience 11(1): 126.
- Ding Y. (7 December 2021), Functions of leptin in tuberculosis and diabetes: multi-omics studies across species (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Supervisor(s): Spaink H.P. & Alia A.
- Ding Y., Raterink R., Marín Juez R., Veneman W.J., Egbers K., Eeden S. van den, Haks M.C., Joosten S.A., Ottenhoff T.H.M., Harms A.C., Alia A., Hankemeier T. & Spaink H.P. (2020), y Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria-infected mice and zebrafish larvae, Scientific Reports 10(1): 11635.
- Ding Y. Raterink R. Marín‑Juez R. Veneman W.J. Egbers K. Eeden S. van den Haks M.C. Joosten S.A. Ottenhof T.H.M. Harms A.C. Alia A. Hankemeier T. Spaink H.P. (2020), Tuberculosis causes highly conserved metabolic changes in human patients, mycobacteria‑infected mice and zebrafish larvae, Scientific Reports 10: 11635.