Theo Stijnen
Professor emeritus Medical Statistics and Bioinformatics
- Name
- Prof.dr. T. Stijnen
- Telephone
- +31 71 526 9701
- t.stijnen@lumc.nl
- ORCID iD
- 0000-0001-9733-969X
Most fascinating of medical statistics for me is that it operates on the border of two sciences. On one hand the world of statistics, a big discipline with a strong mathematical nature with numerous scientific journals, and on the other hand the big world of clinical and epidemiological research. Applying statistical methods in medical research demands a lot of creativity and professional skill. Having been working in this field for more than 25 years I still enjoy it very much. The field of medical research is very dynamic, more and more data are collected per individual and with a more complicated structure, continually giving rise to new challenges for biostatisticians. One of my special interests is meta-analysis. The medical literature is growing enormously and meta-analytical methods to combine, summarize and integrate the results are increasingly necessary. I hope to be able to contribute for a long time to the development of statistical methods in this and other areas.
Professor emeritus Medical Statistics and Bioinformatics
- Faculteit Geneeskunde
- Divisie 4
- Biomedical Data Sciences
- Laven, J.; Wijngaard-Boom, P.; Stijnen, T. & Creutzberg, E. (2020), The use of follitropin delta for ovarian stimulation for in vitro fertilization in patients with anovulatory PCOS: results in clinical practice, Human Reproduction 35: 1455-1456.
- Creutzberg, E.C.; Wijngaard-Boom, P.; Stijnen, T. & Laven, J. (2020), The use of follitropin delta for ovarian stimulation for in vitro fertilization in patients with a low ovarian reserve: results from clinical practice, Human Reproduction 35: 1452-1452.
- Papadimitropoulou, K.; Stijnen, T.; Riley, R.D.; Dekkers, O.M. & Cessie, S. le (2020), Meta-analysis of continuous outcomes, Research Synthesis Methods 11(6).
- Wijngaard-Boom, P.; Creutzberg, E.; Stijnen, T. & Laven, J.S.E. (2020), Individualised follitropin delta dosing for ovarian stimulation in daily practice in a Dutch IVF centre, Human Reproduction 35: 1454-1454.
- Kolk, A.; Zwaal, P. van der; Thomassen, B.J.W.; Kamp, E.W.C. van de; Stijnen, T.; Groot, J.H. de & Nelissen, R.G.H.H. (2018), The presence of a rotator cuff tear interferes with age-dependent muscle atrophy of intact shoulder muscles. An MRI study with 3 years' follow-up, Human Movement Science 62: 161-168.
- Hofstede, S.N.; Gademan, M.G.J.; Stijnen, T.; Nelissen, R.G.H.H.; Marang-van de Mheen, P.J. & ARGON-OPTIMA Study Grp (2018), The influence of preoperative determinants on quality of life, functioning and pain after total knee and hip replacement: a pooled analysis of Dutch cohorts, BMC Musculoskeletal Disorders 19.
- Maier A., Waaijer M., Tuttle C., Slee-Valentijn M., Stijnen T. & Westendorp R. (2018), Cellular senescence and chronological age in various human tissues: a systematic review and meta-analysis, Australasian Journal on Ageing 37: 32-32.
- Blom, J.W.; Hout, W.B. van den; Elzen, W.P.J. den; Drewes, Y.M.; Bleijenberg, N.; Fabbricotti, I.N.; Jansen, A.P.D.; Kempen, G.I.J.M.; Koopmans, R.; Looman, W.M.; Melis, R.J.F.; Metzelthin, S.F.; Charante, E.P.M. van; Muntinga, M.E.; Numans, M.E.; Ruikes, F.G.H.; Spoorenberg, S.L.W.; Stijnen, T.; Suijker, J.J.; Wit, N.J. de; Wynia, K.; Wind, A.W.; Gussekloo, J. & TOPICS-MDS Res Consortium (2018), Effectiveness and cost-effectiveness of proactive and multidisciplinary integrated care for older people with complex problems in general practice: an individual participant data meta-analysis, Age and Ageing 47(5): 705-714.
- Hubers, A.A.M.; Moaddine, S.; Peersmann, S.H.M.; Stijnen, T.; Duijn, E. van; Mast, R.C. van der; Dekkers, O.M. & Giltay, E.J. (2018), Suicidal ideation and subsequent completed suicide in both psychiatric and non-psychiatric populations: a meta-analysis, Epidemiology and Psychiatric Sciences 27(2): 186-198.
- Jackson, D.; Law, M.; Stijnen, T.; Viechtbauer, W. & White, I.R. (2018), A comparison of seven random-effects models for meta-analyses that estimate the summary odds ratio, Statistics in Medicine 37(7): 1059-1085.
- Vessem, M.E. van; Palmen, M.; Couperus, L.E.; Stijnen, T.; Berendsen, R.R.; Aarts, L.P.H.J.; Jonge, E. de; Klautz, R.J.M.; Schalij, M.J. & Beeres, S.L.M.A. (2018), Vasoplegia After Surgical Left Ventricular Restoration: 2-Year Follow-Up, Annals of Thoracic Surgery 106(5): 1371-1378.
- Smelt, A.F.H.; Gussekloo, J.; Bermingham, L.W.; Allen, E.; Dangour, A.D.; Eussen, S.J.P.M.; Favrat, B.; Groot, L.C.P.G.M. de; Kok, F.J.; Kwok, T.; Mangoni, A.A.; Ntaios, G.; Rest, O. van de; Seal, E.; Vaucher, P.; Verhoef, P.; Stijnen, T. & Elzen, W.P.J. den (2018), The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis, European Journal of Clinical Nutrition 72(6): 785-795.
- Esmeijer, K.; Geleijnse, J.M.; Giltay, E.J.; Stijnen, T.; Dekker, F.W.; Fijter, J.W. de; Kromhout, D. & Hoogeveen, E.K. (2018), Body-fat indicators and kidney function decline in older post-myocardial infarction patients: The Alpha Omega Cohort Study, European Journal of Preventive Cardiology 25(1): 90-99.
- Voorn, V.M.A.; Marang-van de Mheen, P.J.; Hout, A. van der; Hofstede, S.N.; So-Osman, C.; Akker-van Marle, M.E. van den; Kaptein, A.A.; Stijnen, T.; Koopman-van Gemert, A.W.M.M.; Dahan, A.; Vlieland, T.P.M.M.V.; Nelissen, R.G.H.H. & Bodegom-Vos, L. van (2017), The effectiveness of a de-implementation strategy to reduce low-value blood management techniques in primary hip and knee arthroplasty: a pragmatic cluster-randomized controlled trial, Implementation Science 12.
- Kerbert, A.J.C.; Chiang, F.W.T.; Werf, M. van der; Stijnen, T.; Slingerland, H.; Verspaget, H.W.; Hoek, B. van & Coenraad, M.J. (2017), Hemodynamic response to primary prophylactic therapy with nonselective beta-blockers is related to a reduction of first variceal bleeding risk in liver cirrhosis: a meta-analysis, European Journal of Gastroenterology and Hepatology 29(4): 380-387.
- Hoogeveen, E.K.; Geleijnse, J.M.; Giltay, E.J.; Soedamah-Muthu, S.S.; Goede, J. de; Griep, L.M.O.; Stijnen, T. & Kromhout, D. (2017), Kidney function and specific mortality in 60-80 years old post-myocardial infarction patients: A 10-year follow-up study, PLoS ONE 12(2).
- Kuppens, R.J.; Bakker, N.E.; Siemensma, E.P.C.; Donze, S.H.; Stijnen, T. & Hokken-Koelega, A.C.S. (2017), Metabolic health profile in young adults with Prader-Willi syndrome: results of a 2-year randomized, placebo-controlled, crossover GH trial, Clinical Endocrinology 86(2): 297-304.
- Bergstra, S.A.; Allaart, C.F.; Stijnen, T. & Landewe, R.B.M. (2017), Meta-Regression of a Dose-Response Relationship of Methotrexate in Mono- and Combination Therapy in Disease-Modifying Antirheumatic Drug-Naive Early Rheumatoid Arthritis Patients.
- Meeteren, M.J.W. van; Hayee, B.; Inderson, A.; Meulen, A.E. van der; Altwegg, R.; Hoek, B. van; Pageaux, G.P.; Stijnen, T.; Stein, D. & Maljaars, P.W.J. (2017), Safety of Anti-TNF Treatment in Liver Transplant Recipients: A Systematic Review and Meta-analysis, Journal of Crohn's and Colitis 11(9): 1146-1151.
- Waars, S.; Dekkers, N.; Meulen, A. van der; Stijnen, T. & Maljaars, J. (2017), Safety of anti-TNF treatment in older IBD patients: a systematic review and meta-analysis, Journal of Crohn's and Colitis 11: S248-S248.
- Meeteren, M.W. van; Inderson, A.; Hayee, B.; Meulen, A. van der; Altwegg, R.; Hoek, B. van; Pageaux, G.P.; Stijnen, T.; Stein, D. & Maljaars, J. (2017), Safety of anti-TNF treatment in liver transplant recipients - a meta-analysis, Journal of Crohn's and Colitis 11: S421-S421.
- Nooij, L.S.; Slot, M.A. van der; Dekkers, O.M.; Stijnen, T.; Gaarenstroom, K.N.; Creutzberg, C.L.; Smit, V.T.H.B.M.; Bosse, T. & Poelgeest, M.I.E. van (2016), Tumour-free margins in vulvar squamous cell carcinoma: Does distance really matter?, European Journal of Cancer 65: 139-149.
- Poelgeest, M.I.E. van; Welters, M.J.P.; Vermeij, R.; Stynenbosch, L.F.M.; Loof, N.M.; Berends-van der Meer, D.M.A.; Lowik, M.J.G.; Hamming, I.L.E.; Esch, E.M.G. van; Hellebrekers, B.W.J.; Beurden, M. van; Schreuder, H.W.; Kagie, M.J.; Trimbos, J.B.M.Z.; Fathers, L.M.; Daemen, T.; Hollema, H.; Valentijn, A.R.P.M.; Oostendorp, J.; Oude Elberink, H.N.G.; Fleuren, G.J.; Bosse, T.; Kenter, G.G.; Stijnen, T.; Nijman, H.W.; Melief, C.J.M. & Burg, S.H. van der (2016), Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response, Clinical Cancer Research 22(10): 2342-2350.
- (2016), Obesity and kidney function decline in 60-80 years old state-of-the-art drug-treated post-myocardial infarction patients.
- Ypma, P.F.; Meer, P.F. van der; Heddle, N.M.; Hilten, J.A. van; Stijnen, T.; Middelburg, R.A.; Hervig, T.; Bom, J.G. van der; Brand, A.; Kerkhoffs, J.L.H. & PREPAReS Study Grp (2016), A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial, BMJ Open 6(1).
- Bergstra, S.A.; Allaart, C.F.; Stijnen, T. & Landewe, R.B.M. (2016), Dose-Related Short Term Clinical Response to Initial Treatment with Methotrexate in Mono- and Combination Therapy in Early Rheumatoid Arthritis Patients - a Meta-Regression Analysis, Arthritis and Rheumatology 68.
- Jansen, F.A.R.; Everwijn, S.M.P.; Scheepjens, R.; Stijnen, T.; Peeters-Scholte, C.M.P.C.D.; Lith, J.M.M. van & Haak, M.C. (2016), Fetal brain imaging in isolated congenital heart defects - a systematic review and meta-analysis, Prenatal Diagnosis 36(7): 601-613.
- Rooden, S.M. van; Verbaan, D.; Stijnen, T.; Marinus, J. & Hilten, J.J. van (2016), The influence of age and approaching death on the course of nondopaminergic symptoms in Parkinson's disease, Parkinsonism and Related Disorders 24: 113-118.
- Nieuwenhuis, W.P.; Steenbergen, H.W. van; Stomp, W.; Stijnen, T.; Huizinga, T.W.J.; Bloem, J.L.; Heijde, D. van der; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2016), The Course of Bone Marrow Edema in Early Undifferentiated Arthritis and Rheumatoid Arthritis A Longitudinal Magnetic Resonance Imaging Study at Bone Level, Arthritis and Rheumatology 68(5): 1080-1088.
- Morris, D.R.; Cunningham, M.A.; Ahimastos, A.A.; Kingwell, B.A.; Pappas, E.; Bourke, M.; Reid, C.M.; Stijnen, T.; Dalman, R.L.; Aalami, O.O.; Lindeman, J.H.; Norman, P.E.; Walker, P.J.; Fitridge, R.; Bourke, B.; Dear, A.E.; Pinchbeck, J.; Jaeggi, R. & Golledge, J. (2016), TElmisartan in the management of abDominal aortic aneurYsm (TEDY): The study protocol for a randomized controlled trial (vol 16, 274, 2015), Trials 17.
- Markusse, I.M.; Akdemir, G.; Dirven, L.; Goekoop-Ruiterman, Y.P.M.; Groenendael, J.H.L.M. van; Han, K.H.; Molenaar, T.H.E.; Cessie, S. le; Lems, W.F.; Lubbe, P.A.H.M. van der; Kerstens, P.J.S.M.; Peeters, A.J.; Ronday, H.K.; Sonnaville, P.B.J. de; Speyer, I.; Stijnen, T.; Wolde, S. ten; Huizinga, T.W.J. & Allaart, C.F. (2016), Long-Term Outcomes of Patients With Recent-Onset Rheumatoid Arthritis After 10 Years of Tight Controlled Treatment, Annals of Internal Medicine 164(8): 523-+.
- Gielen, C.L.I.; Brand, A.; Heerde, W.L. van; Stijnen, T.; Klautz, R.J.M. & Eikenboom, J. (2016), Hemostatic alterations during coronary artery bypass grafting, Thrombosis Research 140: 140-146.
- Blom, J.; Elzen, W. den; Houwelingen, A.H. van; Heijmans, M.; Stijnen, T.; Hout, W. van den & Gussekloo, J. (2016), Effectiveness and cost-effectiveness of a proactive, goal-oriented, integrated care model in general practice for older people. A cluster randomised controlled trial: Integrated Systematic Care for older People-the ISCOPE study, Age and Ageing 45(1): 30-41.
- Kortekaas, M.C.; Kwok, W.Y.; Reijnierse, M.; Stijnen, T. & Kloppenburg, M. (2016), BRIEF REPORT: Association of Inflammation With Development of Erosions in Patients With Hand Osteoarthritis: A Prospective Ultrasonography Study, Arthritis and Rheumatology 68(2): 392-397.
- Jansen, F.A.R.; Everwijn, S.M.P.; Scheepjens, R.; Stijnen, T.; Peeters-Scholte, C.M.P.C.D.; Lith, J.M.M. van & Haak, M.C. (2016), Fetal brain imaging in isolated congenital heart defects – a systematic review and meta-analysis, Prenatal Diagnosis.
- Clabbers, J.M.K.; Boers-Doets, C.B.; Gelderblom, H.; Stijnen, T.; Lacouture, M.E.; Hoeven, K.J.M. van der & Kaptein, A.A. (2016), Xerosis and pruritus as major EGFRI-associated adverse events, Supportive Care in Cancer 24(2): 513-521.
- Nacak, H.; Diepen, M. van; Qureshi, A.R.; Carrero, J.J.; Stijnen, T.; Dekker, F.W. & Evans, M. (2015), Uric acid is not associated with decline in renal function or time to renal replacement therapy initiation in a referred cohort of patients with Stage III, IV and V chronic kidney disease, Nephrology Dialysis Transplantation 30(12): 2039-2045.
- Regeer, M.V.; Versteegh, M.I.M.; Klautz, R.J.M.; Stijnen, T.; Schalij, M.J.; Bax, J.J.; Marsan, N.A. & Delgado, V. (2015), Aortic Valve Repair Versus Replacement for Aortic Regurgitation: Effects on Left Ventricular Remodeling, Journal of Cardiac Surgery 30(1): 13-19.
- Nieuwenhuis, W.P.; Steenbergen, H.W. van; Stomp, W.; Stijnen, T.; Huizinga, T.W.J.; Bloem, J.L.; Heijde, D. van der; Reijnierse, M. & Helm-van Mil, A.H.M. van der (2015), The Course of Bone Marrow Edema in Early Undifferentiated and Rheumatoid Arthritis; A Longitudinal MRI Study on Bone Level, Arthritis and Rheumatology 67.
- Schoot, R.A.; Ommen, C.H. van; Stijnen, T.; Tissing, W.J.E.; Michiels, E.; Abbink, F.C.H.; Raphael, M.F.; Heij, H.A.; Lieverst, J.A.; Spanjaard, L.; Zwaan, C.M.; Caron, H.N. & Wetering, M.D. van de (2015), Prevention of central venous catheter-associated bloodstream infections in paediatric oncology patients using 70% ethanol locks: A randomised controlled multi-centre trial, European Journal of Cancer 51(14): 2031-2038.
- Roach, R.E.J.; Helmerhorst, F.M.; Lijfering, W.M.; Stijnen, T.; Algra, A. & Dekkers, O.M. (2015), Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke, Cochrane Database of Systematic Reviews.
- Manen, J.G. van; Horn, E.K.; Stijnen, T.; Timman, R.; Busschbach, J.J.V. & Verheul, R. (2015), Tailoring psychotherapy in patients with personality disorders: Matching the level of psychological strengths to the level of stabilizing versus destabilizing psychotherapy, Personality and Mental Health 9(2): 133-149.
- Morris, D.R.; Cunningham, M.A.; Ahimastos, A.A.; Kingwell, B.A.; Pappas, E.; Bourke, M.; Reid, C.M.; Stijnen, T.; Dalman, R.L.; Aalami, O.O.; Lindeman, J.H.; Norman, P.E.; Walker, P.J.; Fitridge, R.; Bourke, B.; Dear, A.E.; Pinchbeck, J.; Jaeggi, R. & Golledge, J. (2015), TElmisartan in the management of abDominal aortic aneurYsm (TEDY): The study protocol for a randomized controlled trial, Trials 16.
- Horn, E.K.; Bartak, A.; Meerman, A.M.M.A.; Rossum, B.V.; Ziegler, U.M.; Thunnissen, M.; Soons, M.; Andrea, H.; Hamers, E.F.M.; Emmelkamp, P.M.G.; Stijnen, T.; Busschbach, J.J.V. & Verheul, R. (2015), Effectiveness of Psychotherapy in Personality Disorders Not Otherwise Specified: A Comparison of Different Treatment Modalities, Clinical Psychology and Psychotherapy 22(5): 426-442.
- Horn, E.K.; Verheul, R.; Thunnissen, M.; Delimon, J.; Soons, M.; Meerman, A.M.M.A.; Ziegler, U.M.; Rossum, B.V.; Andrea, H.; Stijnen, T.; Emmelkamp, P.M.G. & Busschbach, J.J.V. (2015), EFFECTIVENESS OF SHORT-TERM INPATIENT PSYCHOTHERAPY BASED ON TRANSACTIONAL ANALYSIS WITH PATIENTS WITH PERSONALITY DISORDERS: A MATCHED CONTROL STUDY USING PROPENSITY SCORE, Journal of Personality Disorders 29(5): 663-683.
- Gielen, C.L.I.; Bruggemans, E.F.; Stijnen, T.; Eikenboom, J.; Tavilla, G.; Brand, A. & Klautz, R.J.M. (2015), Stopping antiplatelet medication before coronary artery bypass graft surgery: is there an optimal timing to minimize bleeding?, European Journal of Cardio-Thoracic Surgery 48(4): E64-E70.
- Rostamian, S.; Mahinrad, S.; Stijnen, T.; Sabayan, B. & Craen, A.J.M. de (2014), Cognitive impairment and risk of stroke: a systematic review and meta-analysis of prospective cohort studies, Stroke 45(5).
- Meijs, J.; Zirkzee, E.J.M.; Schouffoer, A.A.; Henquet, S.M.; Caljouw, M.A.A.; Stijnen, T.; Huizinga, T.W.J.; Schuerwegh, A.J.M. & Vlieland, T.P.M.V. (2014), Health-care utilization in Dutch systemic sclerosis patients, Clinical Rheumatology 33(6): 825-832.
- Hollestein, L.M.; Herk-Sukel, M.P.P. van; Ruiter, R.; Vries, E. de; Mathijssen, R.H.J.; Wiemer, E.A.C.; Stijnen, T.; Coebergh, J.W.W.; Lemmens, V.E.P.P.; Herings, R.M.C.; Stricker, B.H.C. & Nijsten, T. (2014), Incident cancer risk after the start of aspirin use: Results from a Dutch population-based cohort study of low dose aspirin users, International Journal of Cancer 135(1): 157-165.
- Kolfschoten, N.E.; Marang-van de Mheen, P.J.; Wouters, M.W.J.M.; Eddes, E.H.; Tollenaar, R.A.E.M.; Stijnen, T.; Kievit, J. & Dutch Surgical Colorectal Audit (2014), A Combined Measure of Procedural Volume and Outcome to Assess Hospital Quality of Colorectal Cancer Surgery, a Secondary Analysis of Clinical Audit Data, PLoS ONE 9(2).
- Hoogeveen, E.K.; Geleijnse, J.M.; Kromhout, D.; Stijnen, T.; Gemen, E.F.; Kusters, R. & Giltay, E.J. (2014), Effect of Omega-3 Fatty Acids on Kidney Function after Myocardial Infarction: The Alpha Omega Trial, Clinical Journal of the American Society of Nephrology 9(10): 1676-1683.
- Gielen, C.; Dekkers, O.; Stijnen, T.; Schoones, J.; Brand, A.; Klautz, R. & Eikenboom, J. (2014), The effects of pre- and postoperative fibrinogen levels on blood loss after cardiac surgery: a systematic review and meta-analysis, Interactive Cardiovascular and Thoracic Surgery 18(3): 292-298.
- Geest, S. van; Kuijper, B.; Oterdoom, M.; Hout, W. van den; Brand, R.; Stijnen, T.; Assendelft, P.; Koes, B.; Jacobs, W.; Peul, W. & Vleggeert-Lankamp, C. (2014), CASINO: Surgical or Nonsurgical Treatment for cervical radiculopathy, a randomised controlled trial, BMC Musculoskeletal Disorders 15.
- Bonten, T.N.; Plaizier, C.E.I.; Snoep, J.J.D.; Stijnen, T.; Dekkers, O.M. & Bom, J.G. van der (2014), Effect of beta-blockers on platelet aggregation: a systematic review and meta-analysis, British Journal of Clinical Pharmacology 78(5): 940-949.
- Kruis, A.L.; Boland, M.R.S.; Assendelft, W.J.J.; Gussekloo, J.; Tsiachristas, A.; Stijnen, T.; Blom, C.; Sont, J.K.; Rutten-van Molken, M.P.H.M. & Chavannes, N.H. (2014), Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial, BMJ 349.
- Bastos, M. de; Stegeman, B.H.; Rosendaal, F.R.; Vlieg, A.V.; Helmerhorst, F.M.; Stijnen, T. & Dekkers, O.M. (2014), Combined oral contraceptives: venous thrombosis, Cochrane Database of Systematic Reviews.
- Silva, S.L. da; Vellas, B.; Elemans, S.; Luchsinger, J.; Kamphuis, P.; Yaffe, K.; Sijben, J.; Groenendijk, M. & Stijnen, T. (2014), Plasma nutrient status of patients with Alzheimer's disease: Systematic review and meta-analysis, Alzheimer's and Dementia 10(4): 485-502.
- Rostamian, S.; Mahinrad, S.; Stijnen, T.; Sabayan, B. & Craen, A.J.M. de (2014), Cognitive Impairment and Risk of Stroke A Systematic Review and Meta-Analysis of Prospective Cohort Studies, Stroke 45(5): 1342-1348.
- Keyser, C.E. de; Leening, M.J.G.; Romio, S.A.; Jukema, J.W.; Hofman, A.; Ikram, M.A.; Franco, O.H.; Stijnen, T. & Stricker, B.H. (2014), Comparing a marginal structural model with a Cox proportional hazard model to estimate the effect of time-dependent drug use in observational studies: statin use for primary prevention of cardiovascular disease as an example from the Rotterdam Study, European Journal of Epidemiology 29(11): 841-850.
- Schoot, R.; Wetering, M.V. de; Stijnen, T.; Tissing, W.; Heij, H.; Lieverst, J.; Spanjaard, L.; Caron, H.N.; Ommen, C.H. van & Skion-Aristocaths, S. (2014), PREVALENCE OF SYMPTOMATIC AND ASYMPTOMATIC THROMBOSIS IN PEDIATRIC ONCOLOGY PATIENTS WITH TUNNELED CENTRAL VENOUS CATHETERS, Pediatric Blood and Cancer 61: S401-S402.
- Schoot, R.; Ommen, C.H. van; Stijnen, T.; Tissing, W.J.; Heij, H.; Lieverst, J.; Spanjaard, L.; Caron, H.N.; Wetering, M.D.V. de & Aristocaths, S.S. (2014), REDUCTION OF CATHETER ASSOCIATED BLOODSTREAM INFECTIONS IN PAEDIATRIC ONCOLOGY PATIENTS USING ETHANOL LOCKS; A RANDOMIZED CONTROLLED TRIAL, Pediatric Blood and Cancer 61: S108-S109.
- Drewes, Y.M.; Blom, J.W.; Assendelft, W.J.J.; Stijnen, T.; Elzen, W.P.J. den & Gussekloo, J. (2014), Variability in Vulnerability Assessment of Older People by Individual General Practitioners: A Cross-Sectional Study, PLoS ONE 9(11).
- Kortekaas, M.C.; Kwok, W.Y.; Reijnierse, M.; Stijnen, T. & Kloppenburg, M. (2014), Inflammation Is Associated with Erosive Progression in Patients with Hand Osteoarthritis: A Prospective Ultrasonography Study, Arthritis and Rheumatology 66: S800-S800.
- Meijer, C.A.; Stijnen, T.; Wasser, M.N.J.M.; Hamming, J.F.; Bockel, H. van; Lindeman, J.H.N. & Pharmaceutical Aneurysm (2013), Doxycycline for Stabilization of Abdominal Aortic Aneurysms A Randomized Trial.
- Stegeman, B.H.; Bastos, M. de; Rosendaal, F.R.; Vlieg, A.V.; Helmerhorst, F.M.; Stijnen, T. & Dekkers, O.M. (2013), Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis, BMJ 347.
- Biemans, A.A.M.; Kockaert, M.; Akkersdijk, G.P.; Bos, R.R. van den; Maeseneer, M.G.R. de; Cuypers, P.; Stijnen, T.; Neumann, M.H.A. & Nijsten, T. (2013), Comparing endovenous laser ablation, foam sclerotherapy, and conventional surgery for great saphenous varicose veins, Journal of Vascular Surgery 58(3): 727-+.
- Stegeman, S.A.; Nacak, H.; Huvenaars, K.H.J.; Stijnen, T.; Krijnen, P. & Schipper, I.B. (2013), Surgical treatment of Neer type-II fractures of the distal clavicle A meta-analysis, Acta Orthopaedica 84(2): 184-190.
- Klitsie, L.M.; Roest, A.A.W.; Hulst, A.E. van der; Stijnen, T.; Blom, N.A. & Harkel, A.D.J. ten (2013), Assessment of Intraventricular Time Differences in Healthy Children Using Two-Dimensional Speckle-Tracking Echocardiography.
- Urlings-Strop, L.C.; Stegers-Jager, K.M.; Stijnen, T. & Themmen, A.P.N. (2013), Academic and non-academic selection criteria in predicting medical school performance, Medical Teacher 35(6): 497-502.
- Wilbrink, L.A.; Weller, C.M.; Cheung, C.; Stijnen, T.; Haan, J.; Ferrari, M.D. & Terwindt, G.M. (2013), Stepwise web-based questionnaires for diagnosing cluster headache: LUCA and QATCH, Cephalalgia 33(11): 924-931.
- Oosterhout, W.P.J. van; Schoonman, G.G.; Stijnen, T.; Zwet, E.W. van; Terwindt, G.M. & Ferrari, M.D. (2013), Premonitory Symptoms as a Predictor for Migraine Attacks; a Cross-Sectional and Prospective Study, Cephalalgia 33(S8): 76-76.
- Ghidey, W.; Stijnen, T. & Houwelingen, H.C. van (2013), Modelling the effect of baseline risk in meta-analysis: A review from the perspective of errors-in-variables regression, Statistical Methods in Medical Research 22(3): 307-323.
- Hollestein, L.M.; Herk-Sukel, M.P. van; Ruiter, R.; Vries, E. de; Mathijssen, R.H.; Wiemer, E.A.; Stijnen, T.; Lemmens, V.E.; Herings, R.M.; Stricker, B.H. & Nijsten, T. (2013), Low dose aspirin is not associated with a decreased incident skin cancer risk: A population-based cohort study among 1.2 million Dutch inhabitants, Journal of Investigative Dermatology 133: S92-S92.
- Chiang, F.W.T.; Werf, M. van der; Stijnen, T. & Coenraad, M.J. (2013), HEMODYNAMIC MONITORING OF CHRONIC NON-SELECTIVE BETA-BLOCKER THERAPY AS PRIMARY PROPHYLAXIS OF VARICEAL HEMORRHAGE IN CIRRHOTIC PATIENTS: A META-ANALYSIS, Journal of Hepatology 58: S251-S251.
- Klitsie, L.M.; Kuipers, I.M.; Roest, A.A.W.; Hulst, A.E. van der; Stijnen, T.; Hazekamp, M.G.; Blom, N.A. & Harkel, A.D.J. ten (2013), Disparity in right vs left ventricular recovery during follow-up after ventricular septal defect correction in children., European Journal of Cardio-Thoracic Surgery 44(2): 269-74.
- Klitsie, L.M.; Kuipers, I.M.; Roest, A.A.W.; Hulst, A.E. van der; Stijnen, T.; Hazekamp, M.G.; Blom, N.A. & Harkel, A.D.J. ten (2013), Disparity in right vs left ventricular recovery during follow-up after ventricular septal defect correction in children.
- Fiocco M., Stijnen T. & Putter H. (2012), Meta-analysis of time-to-event outcomes using a hazard-based approach: Comparison with other models, robustness and meta-regression, Computational Statistics & Data Analysis 56(5): 1028-1037.
- Gast, K.B.; Tjeerdema, N.; Stijnen, T.; Smit, J.W.A. & Dekkers, O.M. (2012), Insulin Resistance and Risk of Incident Cardiovascular Events in Adults without Diabetes: Meta-Analysis, PLoS ONE 7(12): -.
- Weele, G.M. van der; Waal, M.W.M. de; Hout, W.B. van den; Craen, A.J.M. de; Spinhoven, P.; Stijnen, T.; Assendelft, W.J.J.; Mast, R.C. van der & Gussekloo, J. (2012), Effects of a stepped-care intervention programme among older subjects who screened positive for depressive symptoms in general practice: the PROMODE randomised controlled trial, Age and Ageing 41(4): 482-488.
- Genders, T.S.S.; Spronk, S.; Stijnen, T.; Steyerberg, E.W.; Lesaffre, E. & Hunink, M.G.M. (2012), Methods for Calculating Sensitivity and Specificity of Clustered Data: A Tutorial, Radiology 265(3): 910-916.
- Zwartele, R.E.; Witjes, S.; Doets, H.C.; Stijnen, T. & Poll, R.G. (2012), Cementless total hip arthroplasty in rheumatoid arthritis: a systematic review of the literature, Archives of Orthopaedic and Trauma Surgery 132(4): 535-546.
- Geerts, B.F.; Bergh, L. van den; Stijnen, T.; Aarts, L.P.H.J. & Jansen, J.R.C. (2012), Comprehensive review: is it better to use the Trendelenburg position or passive leg raising for the initial treatment of hypovolemia?, Journal of Clinical Anesthesia 24(8): 668-674.
- Leunissen, R.W.J.; Kerkhof, G.F.; Stijnen, T. & Hokken-Koelega, A.C.S. (2012), Effect of Birth Size and Catch-Up Growth on Adult Blood Pressure and Carotid Intima-Media Thickness, Hormone Research in Paediatrics 77(6): 394-401.
- Gast, K.B.; Tjeerdema, N.; Stijnen, T.; Smit, J.W.A. & Dekkers, O.M. (2012), Insulin Resistance and Risk of Incident Cardiovascular Events in Adults without Diabetes: Meta-Analysis., PLoS ONE 7(12): e52036.
- Liem, Y.S.; Wong, J.B.; Winkelmayer, W.C.; Weimar, W.; Wetzels, J.F.M.; Charro, F.T. de; Kaandorp, G.C.; Stijnen, T. & Hunink, M.G.M. (2012), Quantifying the benefit of early living-donor renal transplantation with a simulation model of the Dutch renal replacement therapy population.
- Stegeman, S.A.; Nacak, H.; Huvenaars, K.H.J.; Stijnen, T.; Krijnen, P. & Schipper, I.B. (2012), Surgical treatment of Neer type II fractures of the distal clavicle: a meta-analysis.
- A'Campo, L.E.I.; Wekking, E.M.; Spliethoff-Kamminga, N.G.A.; Stijnen, T. & Roos, R.A.C. (2012), Treatment effect modifiers for the patient education programme for Parkinson's disease., International Journal of Clinical Practice 66(1): 77-83.
- Hoogeveen, E.K.; Halbesma, N.; Rothman, K.J.; Stijnen, T.; Dijk, S. van; Dekker, F.W.; Boeschoten, E.W.; Mutsert, R. de & Netherlands Cooperative Study Adeq (2012), Obesity and Mortality Risk among Younger Dialysis Patients, Clinical Journal of the American Society of Nephrology 7(2): 280-288.
- Fiocco, M.; Stijnen, T. & Putter, H. (2012), Meta-analysis of time-to-event outcomes using a hazard-based approach: Comparison with other models, robustness and meta-regression, Computational Statistics and Data Analysis 56(5): 1028-1037.
- Kortekaas, K.A.; Lindeman, J.H.N.; Versteegh, M.I.M.; Stijnen, T.; Dion, R.A.E. & Klautz, R.J.M. (2012), Preexisting heart failure is an underestimated risk factor in cardiac surgery., Netherlands Heart Journal.
- Ahmed, T.A.N.; Bergheanu, S.C.; Stijnen, T.; Plevier, J.W.M.; Quax, P.H.A. & Jukema, J.W. (2011), Clinical outcomes of biodegradable-polymer drug eluting stents, a meta-analysis and systematic review of randomized and observational studies, European Heart Journal 32: 410-410.
- Ahmed, T.A.N.; Bergheanu, S.C.; Stijnen, T.; Plevier, J.W.M.; Quax, P.H.A. & Jukema, J.W. (2011), Clinical performance of drug-eluting stents with biodegradable polymeric coating: a meta-analysis and systematic review, Eurointervention 7(4): 505-516.
- Eeren, H. van; Spreeuwenberg, M.D.; Manen, J.G. van; Rooij, M. de; Stijnen, T. & Busschbach, J. (2011), FINDING TREATMENT EFFECTS WITHIN SUBGROUPS WHEN USING THE PROPENSITY SCORE TO CONTROL FOR SELECTION BIAS: A MONTE CARLO SIMULATION STUDY.
- Bartak, A.; Andrea, H.; Spreeuwenberg, M.D.; Ziegler, U.M.; Dekker, J.; Rossum, B.V.; Hamers, E.F.M.; Scholte, W.; Aerts, J.; Busschbach, J.J.V.; Verheul, R.; Stijnen, T. & Emmelkamp, P.M.G. (2011), Effectiveness of Outpatient, Day Hospital, and Inpatient Psychotherapeutic Treatment for Patients with Cluster B Personality Disorders, Psychotherapy and Psychosomatics 80(1): 28-38.
- Kolfschoten, N.; Mheen, P.J.M. van de; Wouters, M.W.J.M.; Eddes, E.H.; Tollenaar, R.A.E.M.; Stijnen, T. & Kievit, J. (2011), A Combined Volume and Quality Threshold to Reliably Assess Hospital Performance, European Journal of Cancer 47: S412-S412.
- Rees, J.B. van; Borleffs, C.J.W.; Bie, M.K. de; Stijnen, T.; Erven, L. van; Bax, J.J. & Schalij, M.J. (2011), Inappropriate implantable cardioverter-defibrillator shocks incidence, predictors, and impact on mortality.
- Trouw, L.A.; Kurreeman, F.A.S.; Daha, N.; Bohringer, S.; Stoeken-Rijsbergen, G.; Houwing-Duistermaat, J.J.; Huizinga, T.W. & Toes, R.E. (2011), GENETIC VARIANTS OF C1Q ARE A RISK FOR RHEUMATOID ARTHRITIS, Annals of the Rheumatic Diseases 70: A17A17.
- Snel, M.; Diepen, J.A. van; Stijnen, T.; Pijl, H.; Romijn, J.A.; Meinders, A.E.; Voshol, P. & Jazet, I.M. (2011), Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients.
- Koerkamp, B.G.; Stijnen, T.; Weinstein, M.C. & Hunink, M.G.M. (2011), The Combined Analysis of Uncertainty and Patient Heterogeneity in Medical Decision Models, Medical Decision Making 31(4): 650-661.
- Urlings-Strop, L.C.; Themmen, A.P.N.; Stijnen, T. & Splinter, T.A.W. (2011), Selected medical students achieve better than lottery-admitted students during clerkships, Medical Education 45(10): 1032-1040.
- Bartak, A.; Andrea, H.; Spreeuwenberg, M.D.; Thunnissen, M.; Ziegler, U.M.; Dekker, J.; Bouvy, F.; Hamers, E.F.M.; Meerman, A.M.M.A.; Busschbach, J.J.V.; Verheul, R.; Stijnen, T. & Emmelkamp, P.M.G. (2011), Patients with Cluster A Personality Disorders in Psychotherapy: An Effectiveness Study, Psychotherapy and Psychosomatics 80(2): 88-99.
- Menke, L.A.; Sas, T.C.J.; Stijnen, T.; Zandwijken, G.R.J.; Keizer-Schrama, S.M.P.F.D.; Otten, B.J. & Wit, J.M. (2011), Effect of Oxandrolone on Glucose Metabolism in Growth Hormone-Treated Girls with Turner Syndrome, Hormone Research in Paediatrics 75(2): 115-122.
- Manen, J.G. van; Andrea, H.; Eijnden, E. van den; Meerman, A.M.M.A.; Thunnissen, M.M.; Hamers, E.F.M.; Huson, N.; Ziegler, U.; Stijnen, T.; Busschbach, J.J.V.; Timman, R. & Verheul, R. (2011), RELATIONSHIP BETWEEN PATIENT CHARACTERISTICS AND TREATMENT ALLOCATION FOR PATIENTS WITH PERSONALITY DISORDERS, Journal of Personality Disorders 25(5): 656-667.
- Oosterhout, W.P.J. van; Weller, C.M.; Stam, A.H.; Bakels, F.; Stijnen, T.; Ferrari, M.D. & Terwindt, G.M. (2011), Validation of the web-based LUMINA questionnaire for recruiting large cohorts of migraineurs.
- Snel, M.; Diepen, J.A. van; Stijnen, T.; Pijl, H.; Romijn, J.A.; Meinders, A.E.; Voshol, P. & Jazet, I.M. (2011), Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients.
- Putter H., Fiocco M. & Stijnen T. (2010), Meta-Analysis of Diagnostic Test Accuracy Studies with Multiple Thresholds using Survival Methods, Biometrical Journal 52(1): 95-110.
- Gooiker G, Verbeek L, van der Geest LGM, Stijnen T, Dekker JWR, Nortier JWR, Marinelli A, Struikmans H, Wouters MWJM & Tollenaar RAEM (2010), The quality indicator "tumour positive margin rate after breast conserving surgery": a valid assessment of hospital performance?, EJC Supplements.
- Gooiker, G.; Veerbeek, L.; Geest, L.G.M. van der; Stijnen, T.; Dekker, J.W.R.; Nortier, J.W.R.; Marinelli, A.; Struikmans, H.; Wouters, M.W.J.M. & Tollenaar, R.A.E.M. (2010), The quality indicator 'tumour positive margin rate after breast conserving surgery': a valid assessment of hospital performance?, EJC Supplements 8(3): 206-206.
- Luppino, F.S.; Wit, L.M. de; Bouvy, P.F.; Stijnen, T.; Cuijpers, P.; Penninx, B.W.J.H. & Zitman, F.G. (2010), Overweight, Obesity, and Depression A Systematic Review and Meta-analysis of Longitudinal Studies, Archives of General Psychiatry 67(3): 220-229.
- Luppino, F.S.; Wit, L.M. de; Bouvy, P.F.; Stijnen, T.; Cuijpers, P.; Penninx, B.W.J.H. & Zitman, F.G. (2010), Overweight, Obesity, and Depression: A Systematic Review and Meta-analysis of Longitudinal Studies., Archives of General Psychiatry 67(3): 220-9.
- Koerkamp, B.G.; Spronk, S.; Stijnen, T. & Hunink, M.G.M. (2010), Value of Information Analyses of Economic Randomized Controlled Trials: The Treatment of Intermittent Claudication, Value in Health 13(2): 242-250.
- Koerkamp, B.G.; Weinstein, M.C.; Stijnen, T.; Heijenbrok-Kal, M.H. & Hunink, M.G.M. (2010), Uncertainty and Patient Heterogeneity in Medical Decision Models, Medical Decision Making 30(2): 194-205.
- Spreeuwenberg, M.D.; Bartak, A.; Croon, M.A.; Hagenaars, J.A.; Busschbach, J.J.V.; Andrea, H.; Twisk, J. & Stijnen, T. (2010), The Multiple Propensity Score as Control for Bias in the Comparison of More Than Two Treatment Arms An Introduction From a Case Study in Mental Health, Medical Care 48(2): 166-174.
- Stijnen, T.; Hamza, T.H. & Ozdemir, P. (2010), Random effects meta-analysis of event outcome in the framework of the generalized linear mixed model with applications in sparse data, Statistics in Medicine 29(29): 3046-3067.
- Beenakker, K.G.M.; Ling, C.H.; Meskers, C.G.M.; Craen, A.J.M. de; Stijnen, T.; Westendorp, R.G.J. & Maier, A.B. (2010), Patterns of muscle strength loss with age in the general population and patients with a chronic inflammatory state, Ageing Research Reviews 9(4): 431-436.
- Hassan, A.K.M.; Bergheanu, S.C.; Stijnen, T.; Hoeven, B.L. van der; Snoep, J.D.; Plevier, J.W.M.; Schalij, M.J. & Jukema, J.W. (2010), Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis, European Heart Journal 31(10): 1172-1180.
- Stricker, B.H.C. & Stijnen, T. (2010), Analysis of individual drug use as a time-varying determinant of exposure in prospective population-based cohort studies, European Journal of Epidemiology 25(4): 245-251.
- Niesters, M.; Dahan, A.; Kest, B.; Zacny, J.; Stijnen, T.; Aarts, L. & Sarton, E. (2010), Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies, PAIN 151(1): 61-68.
- Bartak, A.; Spreeuwenberg, M.D.; Andrea, H.; Holleman, L.; Rijnierse, P.; Rossum, B.V.; Hamers, E.F.M.; Meerman, A.M.M.A.; Aerts, J.; Busschbach, J.J.V.; Verheul, R.; Stijnen, T. & Emmelkamp, P.M.G. (2010), Effectiveness of different modalities of psychotherapeutic treatment for patients with cluster C personality disorders: results of a large prospective multicentre study., Psychotherapy and Psychosomatics 79(1): 20-30.
- Putter, H.; Cessie, S. le & Stijnen, T. (2010), Hans van Houwelingen, 40 years in biostatistics., Biometrical Journal 52(1): 5-9.
- Gooiker, G.; Veerbeek, L.; Geest, L.G.M. van der; Stijnen, T.; Dekker, J.W.R.; Nortier, J.W.R.; Marinelli, A.; Struikmans, H.; Wouters, M.W.J.M. & Tollenaar, R.A.E.M. (2010), The quality indicator 'tumour positive margin rate after breast conserving surgery': a valid assessment of hospital performance?, EJC Supplements 8(3): 206-206.
- Putter, H.; Fiocco, M. & Stijnen, T. (2010), Meta-Analysis of Diagnostic Test Accuracy Studies with Multiple Thresholds using Survival Methods, Biometrical Journal 52(1): 95-110.
- Lebrec, J.J.; Stijnen, T. & Houwelingen, H.C. van (2010), Dealing with Heterogeneity between Cohorts in Genomewide SNP Association Studies, Statistical Applications in Genetics and Molecular Biology 9(1).
- Putter, H.; Cessie, S. le & Stijnen, T. (2010), Hans van Houwelingen, 40 Years in Biostatistics, Biometrical Journal 52(1): 5-9.
- Gooiker GA, Veerbeek L, van der Geest LG, Stijnen T, Dekker JW, Nortier JW, Marinelli AW, Struikmans H, Wouters MW & Tollenaar RA (2010), [The quality indicator 'tumour positive surgical margin following breast-conserving surgery' does not provide transparent insight into care].
- Putter, H.; Cessie, S. le & Stijnen, T. (2010), Hans van Houwelingen, 40 years in Biostatistics, Biometrical Journal.
- Lebrec, J.J.; Stijnen, T. & Houwelingen, H.C. van (2010), Dealing with heterogeneity between Cohorts in Genomewide SNP Association Studies, Statistical Applications in Genetics and Molecular Biology.
- Niesters M, Dahan A, Kest B, Zacny J, Stijnen T, Aarts L & Sarton E (2010), Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies, PAIN.
- Menke, L.A.; Sas, T.C.J.; Zandwijken, G.R.J.; Ridder, M.A.J. de; Stijnen, T.; Keizer-Schrama, S.M.P.F.D.; Otten, B.J. & Wit, J.M. (2010), The effect of oxandrolone on body proportions and body composition in growth hormone-treated girls with Turner syndrome, Clinical Endocrinology.
- Goeman, J.J.; Solari, A. & Stijnen, T. (2010), Three-sided hypothesis testing: Simultaneous testing of superiority, equivalence and inferiority, Statistics in Medicine 29(20): 2117-2125.
- Leunissen, R.W.J.; Gao, Y.; Cianflone, K.; Stijnen, T. & Hokken-Koelega, A.C.S. (2010), Growth patterns during childhood and the relationship with acylation-stimulating protein, Clinical Endocrinology.
- Stricker, B.H.C. & Stijnen, T. (2010), Analysis of individual drug use as a time-varying determinant of exposure in prospective population-based cohort studies, European Journal of Epidemiology.
- Niel-Weise, B.S.; Stijnen, T. & Broek, P.J. van den (2010), Should In-line Filters Be Used in Peripheral Intravenous Catheters to Prevent Infusion-Related Phlebitis? A Systematic Review of Randomized Controlled Trials, Anesthesia and Analgesia 110(6): 1624-1629.
- Menke, L.A.; Sas, T.C.J.; Visser, M.; Kreukels, B.P.C.; Stijnen, T.; Zandwijken, G.R.J.; Keizer-Schrama, S.M.P.F.D.; Otten, B.J.; Wit, J.M. & Cohen-Kettenis, P.T. (2010), The effect of the weak androgen oxandrolone on psychological and behavioral characteristics in growth hormone-treated girls with Turner syndrome.
- Menke, L.A.; Sas, T.C.J.; Zandwijken, G.R.J.; Ridder, M.A.J. de; Stijnen, T.; Keizer-Schrama, S.M.P.F.D.; Otten, B.J. & Wit, J.M. (2010), The effect of oxandrolone on body proportions and body composition in growth hormone-treated girls with Turner syndrome, Clinical Endocrinology 73(2): 212-219.
- Gooiker, G.A.; Veerbeek, L.; Geest, L.G.M. van der; Stijnen, T.; Dekker, J.W.T.; Nortier, J.W.R.; Marinelli, A.W.K.S.; Struikmans, H.; Wouters, M.W.J.M. & Tollenaar, R.A.E.M. (2010), De prestatie-indicator 'irradicaliteit na borstsparende operatie', Nederlands Tijdschrift voor Geneeskunde 154.
- Kerkhof GF, Leunissen RW, Willemsen RH, de Jong FH, Stijnen T & Hokken-Koelega AC (2009), Influence of preterm birth and birth size on gonadal function in young men.
- Aziz, N.A.; Jurgens, C.K.; Landwehrmeyer, G.B.; Roon-Mom, W.M.C. van; Ommen, G.J.B. van; Stijnen, T.; Roos, R.A.C.; Orth, M.; Handley, O.J.; Schwenke, C.; Ho, A.; Wild, E.J.; Tabrizi, S.J.; Landwehrmeyer, G.B.; Bachoud-Levi, A.C.; Bentivoglio, A.R.; Biunno, I.; Bonelli, R.; Burgunder, J.M.; Dunnett, S.B.; Ferreira, J.J.; Handley, O.J.; Heiberg, A.; Illman, T.; Levey, J.; Nielsen, J.E.; Paivarinta, M.; Roos, R.A.C.; Sebastian, A.R.; Tabrizi, S.J.; Vandenberghe, W.; Verellen-Dumoulin, C.; Zaremba, J.; Uhrova, T.; Wahlstrom, J.; Wallner, M.; Barth, K.; Garde, M.B.; Bos, R.; Ecker, D.; Handley, O.J.; Heinonen, N.; Held, C.; Laura, M.; Descals, A.M.; Mestre, T.; Monza, D.; Naji, J.; Padieu, H.; Koivisto, S.P.; Rialland, A.; Sasinkova, P.; Cubillo, P.T.; Walsem, M. van; Witjes-Ane, M.N.; Zielonka, D.; Bonelli, R.M.; Herranhof, B.; Hodl, A.; Koppitz, M.; Magnet, M.; Otti, D.; Painold, A.; Reisinger, K.; Flamez, A.; Morez, V.; Raedt, S. de; Ribai, P.; Verellen-Dumoulin, C.; Vandenberghe, W.; Reijen, D. van; Hasholt, L.; Hjermind, L.E.; Jakobsen, O.; Norremolle, A.; Sorensen, S.A.; Stokholm, J.; Peippo, M.; Sipponen, M.; Hiivola, H.; Martikainen, K.; Tuuha, K.; Kosinski, C.M.; Probst, D.; Sass, C.; Schiefer, J.; Schlangen, C.; Werner, C.J.; Priller, J.; Pruss, H.; Andrich, J.; Hoffmann, R.; Kraus, P.; Prehn, C.; Saft, C.; Salmen, S.; Strassburger, K.; Lange, H.; Hunger, U.; Lohle, M.; Schmidt, S.; Storch, A.; Wolz, A.; Wolz, M.; Lammbeck, J.; Zucker, B.; Hidding, U.; Munchau, A.; Orth, M.; Stubbe, L.; Heinicke, W.; Longinus, B.; Moller, J.C.; Rissling, I.; Peinemann, A.; Stadtler, M.; Weindl, A.; Bohlen, S.; Lange, H.; Reilmann, R.; Beister, A.; Dose, M.; Leythaeuser, G.; Marquard, R.; Schrenk, C.; Schuierer, M.; Wiedemann, A.; Ecker, D.; Landwehrmeyer, B.; Lezius, F.; Trautmann, S.; Bertini, E.; Mechi, C.; Paganini, M.; Piacentini, S.; Romoli, M.; Sorbi, S.; Abbruzzese, G.; Ferrandes, M.B.D.G.; Mandes, P.; Marchese, R.; Albanese, A.; Donato, S. di; Mariotti, C.; Soliveri, P.; Carlo, R.; Luigi, D.M.; Michele, G. de; Rinaldi, C.; Salvatore, E.; Tucci, T.; Ciarmiello, A.; Martino, T.; Simonelli, M.; Squitieri, F.; Bentivoglio, A.R.; Fasano, A.; Frontali, M.; Guidubaldi, A.; Ialongo, T.; Jacopini, G.; Loria, G.; Piano, C.; Romano, S.; Soleti, F.; Spadaro, M.; Zinzi, P.; Heiberg, A.; Walsem, M.R. van; Bjorgo, K.; Fannemel, M.; Gorvell, P.; Retterstol, L.; Bjornevoll, I.; Sando, S.B.; Sitek, E.J.; Slawek, J.; Soltan, W.; Rudzinska, M.; Szczudlik, A.; Wojcik, M.; Bryl, A.; Ciesielska, A.; Klimberg, A.; Kozubski, W.; Marcinkowski, J.; Sempolowicz, P.J.; Zielonka, D.; Janik, P.; Kalbarczyk, A.; Kwiecinski, H.; Jamrozik, Z.; Antczak, J.; Rakowicz, M.; Richter, P.; Ryglewicz, D.; Zaremba, J.; Zdzienicka, E.; Costa, C.; Coelho, M.; Ferreira, J.J.; Mestre, T.; Rosa, M.M.; Valadas, A.; Gago, M.; Garrett, C.; Guerra, M.R.; Bas, J.; Calopa, M.; Barbera, M.A.; Badenes, D.; Casas, L.; Arroyo, S.E.; Vara, J.H.; Krupinski, J.; Lopez, J.; Obdulia, M.; Ferrer, P.Q.; Sebastian, A.R.; Contreras, S.R.; Carruesco, G.T.; Cubo, E.; Mariscal, N.; Sanchez, J.; Barrero, F.J.; Morales, B.; Moreno, J.L.L.S.; Garcia, R.G.R.; Quiroga, P.P.; Villanueva, C.; Ruiz-Espiga, P.J.G.; Martinez, A.; Artiga, M.J.S.; Sanchez, V.; Bascunana, M.; Fatas, M.; Ribas, G.G.; Yebenes, J.G. de; Moreno, J.L.L.; Schwarz, C.; Cubillo, P.T.; Arques, P.N.; Gorospe, A.; Legarda, I.; Rodriguez, M.J.T.; Gaston, I.; Ramos-Arroyo, M.A.; Val, J.L. del; Martinez, L.; Burgunder, J.M.; Romero, I.; Schupbach, M.; Zaugg, S.W.; Hout, M.S.E. van; Vugt, J.P.P. van; Weert, A.M. de; Bolwijn, J.J.W.; Dekker, M.; Leenders, K.L.; Oostrom, J.C.H. van; Bos, R.; Dumas, E.; Jurgens, C.K.; Roos, R.A.C.; Witjes-Ane, M.N.; Matheson, K.; Rae, D.; Simpson, S.; Summers, F.; Ure, A.; Curtis, A.; Keylock, J.; Rickards, H.; Wright, J.; Barker, R.A.; Fisher, K.; Goodman, A.O.G.; Hill, S.; Kershaw, A.; Mason, S.; Paterson, N.; Raymond, L.; Bisson, J.; Busse, M. & Ellison-Rose, L (2009), Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease, Neurology 73(16): 1280-1285.
- Oudkerk-Pool M, Dignass AU, Stijnen T & Veerman H (2009), Maintenance therapy with once-daily 2 g mesalazine (Pentasa) treatment improves remission rates in subjects with ulcerative colitis compared to twice daily 1 g mesalazine: data from a randomised controlled trial, European Journal of Gastroenterology and Hepatology 21(3): A32A33.
- van Houwelingen HC, Lebrec JJP & Stijnen T (2009), Heterogeneity in meta-analysis of genomewide association scans, Annals of Human Genetics 73: 661-661.
- Leunissen RW, Stijnen T & Hokken-Koelega AC (2009), Influence of birth size on body composition in early adulthood: the programming factors for growth and metabolism (PROGRAM)-study.
- Hamza TH, van Houwelingen HC, Heijenbrok-Kal MH & Stijnen T (2009), Associating explanatory variables with summary receiver operating characteristic curves in diagnostic meta-analysis.
- Veerman AJ, Kamps WA, van den Berg H, van den Berg E, Bökkerink JP, Bruin MC, van den Heuvel-Eibrink MM, Korbijn CM, Korthof ET, van der Pal K, Stijnen T, van Weel Sipman MH, van Weerden JF, van Wering ER, van der Does-van den Berg A & (2009), Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004)., Lancet Oncology 10(10): 957-66.
- Koerkamp BG, Spronk S, Stijnen T & Hunink MG (2009), Value of Information Analyses of Economic Randomized Controlled Trials: The Treatment of Intermittent Claudication.
- Hassan AK, Bergheanu SC, Stijnen T, van der Hoeven BL, Snoep JD, Plevier JW, Schalij MJ & Jukema JW (2009), Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis., European Heart Journal.
- Leunissen RWJ, Kerkhof GF, Stijnen T & Hokken-Koelega A (2009), Timing and Tempo of First-Year Rapid Growth in Relation to Cardiovascular and Metabolic Risk Profile in Early Adulthood, Journal of the American Medical Association 301(21): 2234-2242.
- Kerkhof GF, Leunissen RWJ, Willemsen RH, de Jong FH, Stijnen T & Hokken-Koelega ACS (2009), Influence of preterm birth and birth size on gonadal function in young men, Journal of Clinical Endocrinology and Metabolism 72: 442-442.
- Leunissen RWJ, Stijnen T & Hokken-Koelega ACS (2009), Influence of birth size on body composition in early adulthood: the programming factors for growth and metabolism (PROGRAM)-study, Clinical Endocrinology 70(2): 245-251.
- Leunissen RW, Kerkhof GF, Stijnen T & Hokken-Koelega A (2009), Timing and tempo of first-year rapid growth in relation to cardiovascular and metabolic risk profile in early adulthood., Journal of the American Medical Association 301(21): 2234-42.
- Bartak A, Spreeuwenberg MD, Andrea H, Busschbach JJ, Croon MA, Verheul R, Emmelkamp PM & Stijnen T (2009), The use of propensity score methods in psychotherapy research. A practical application., Psychotherapy and Psychosomatics 78(1): 26-34.
- Urlings-Strop LC, Stijnen T, Themmen AP & Splinter TA (2009), Selection of medical students: a controlled experiment., Medical Education 43(2): 175-83.
- Snoei L, van Bodegraven A, Oldenburg B, Stijnen T & Kaptein AA (2009), Prototype evaluation of a self-management Internet diary for patients with ulcerative colitis., Patient Preference and Adherence 3: 179-87.
- Aziz NA, Jurgens CK, Landwehrmeyer GB, , van Roon-Mom WM, van Ommen GJ, Stijnen T & Roos RA (2009), Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease., Neurology 73(16): 1280-5.
- Bartak A, Spreeuwenberg MD, Andrea H, Busschbach JJV, Croon MA, Verheul R, Emmelkamp PMG & Stijnen T (2009), The Use of Propensity Score Methods in Psychotherapy Research A Practical Application, Psychotherapy and Psychosomatics 78(1): 26-34.
- Urlings-Strop LC, Stijnen T, Themmen APN & Splinter TAW (2009), Selection of medical students: a controlled experiment, Medical Education 43(2): 175-183.
- Adriaensen MEAPM, Schaefer-Prokop CM, Stijnen T, Duyndam DAC, Zonnenberg BA & Prokop M (2009), Prevalence of subependymal giant cell tumors in patients with tuberous sclerosis and a review of the literature.
- Adriaensen ME, Schaefer-Prokop CM, Stijnen T, Duyndam DA, Zonnenberg BA & Prokop M (2009), Prevalence of subependymal giant cell tumors in patients with tuberous sclerosis and a review of the literature., European Journal of Neurology 16(6): 691-6.
- van Durme YMTA, Verhamme KMC, Stijnen T, van Rooij FJA, Van Pottelberge GR, Hofman A, Joos GF, Stricker BHC & Brusselle GG (2009), Prevalence, Incidence, and Lifetime Risk for the Development of COPD in the Elderly The Rotterdam Study, Chest 135(2): 368-377.
- Willemsen RH, Leunissen RWJ, Stijnen T & Hokken-Koelega ACS (2009), Prematurity Is Not Associated with Reduced Insulin Sensitivity in Adulthood, Journal of Clinical Endocrinology and Metabolism 94(5): 1695-1700.
- Dignass AU, Bokemeyer B, Adamek H, Mross M, Vinter-Jensen L, Borner N, Silvennoinen J, Tan G, Pool MO & Stijnen T (2009), Mesalamine Once Daily Is More Effective Than Twice Daily in Patients With Quiescent Ulcerative Colitis, Clinical Gastroenterology and Hepatology 7(7): 762-769.
- Kerkhof GF, Leunissen RWJ, Willemsen RH, de Jong FH, Stijnen T & Hokken-Koelega ACS (2009), Influence of Preterm Birth and Birth Size on Gonadal Function in Young Men, Journal of Clinical Endocrinology and Metabolism 94(11): 4243-4250.
- van Houwelingen HC, Lebrec JJP & Stijnen T (2009), Heterogeneity in meta-analysis of genomewide association scans, Annals of Human Genetics 73: 661-661.
- Hamza TH, van Houwelingen HC, Heijenbrok-Kal MH & Stijnen T (2009), Associating explanatory variables with summary receiver operating characteristic curves in diagnostic meta-analysis, Journal of Clinical Epidemiology 62(12): 1284-1291.
- van Durme YM, Verhamme KM, Stijnen T, van Rooij FJ, Van Pottelberge GR, Hofman A, Joos GF, Stricker BH & Brusselle GG (2009), Prevalence, incidence, and lifetime risk for the development of COPD in the elderly: the Rotterdam study.
- Willemsen RH, Leunissen RW, Stijnen T & Hokken-Koelega AC (2009), Prematurity is not associated with reduced insulin sensitivity in adulthood.
- Hamza TH, Arends LR, van Houwelingen HC & Stijnen T (2009), Multivariate random effects meta-analysis of diagnostic tests with multiple thresholds., BMC Medical Research Methodology 9: 73.
- Dignass AU, Bokemeyer B, Adamek H, Mross M, Vinter-Jensen L, Börner N, Silvennoinen J, Tan G, Pool MO, Stijnen T, Dietel P, Klugmann T, Vermeire S, Bhatt A & Veerman H (2009), Mesalamine once daily is more effective than twice daily in patients with quiescent ulcerative colitis.
- Veerman AJ, Kamps WA, van den Berg H, van den Berg E, Bokkerink JPM, Bruin MCA, van den Heuvel-Eibrink MM, Korbijn CM, Korthof ET & van der Pal K (2009), Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004), Lancet Oncology 10(10): 957-966.
- de Ridder MAJ, Engels MAMJ, Stijnen T & Hokken-Koelega ACS (2008), Small for gestational age children without early catch-up growth: Spontaneous growth and prediction of height at 8 years, Hormone Research 70(4).
- El Galta R, Stijnen T & Houwing-Duistermaat JJ (2008), Testing for genetic association: A powerful score test, Statistics in Medicine 27(22).
- Aziz NA, van der Burg JMM, Landwehrmeyer GB, Brundin P, Stijnen T & Roos RAC (2008), Weight loss in Huntington disease increases with higher CAG repeat number, Neurology 71(19).
- Hamza TH, Reitsma JB & Stijnen T (2008), Meta-analysis of diagnostic studies: A comparison of random intercept, normal-normal, and binomial-normal bivariate summary ROC approaches, Medical Decision Making 28(5).
- Arends LR, Hamza TH, van Houwelingen JC, Heijenbrok-Kal MH, Hunink MGM & Stijnen T (2008), Bivariate random effects meta-analysis of ROC curves, Medical Decision Making 28(5).
- Hassan AKM, Bergheanu S, Stijnen T, Van der Hoeven B, Snoep J, Plevier J, Schalij M & Jukema JW (2008), Late Acquired Stent Malapposition is Higher After Drug-Eluting Stent Compared to Bare-Metal Stent Implantation and is Associated with (Very) Late Stent Thrombosis: Meta-Analysis and Systematic Review, American Journal of Cardiology 102(8A): 198I198I.
- Herba CM, Ferdinand RF, Stijnen T, Veenstra R, Oldehinkel AJ, Ormel J & Verhulst FC (2008), Victimisation and suicide ideation in the TRAILS study: specific vulnerabilities of victims, Journal of Child Psychology and Psychiatry 49(8).
- Koerkamp BG, Nikken JJ, Oei EH, Stijnen T, Ginai AZ & Hunink MGM (2008), Value of information analysis used to determine the necessity of additional research: MR imaging in acute knee trauma as an example, Radiology 246(2).
- de Ridder MAJ, Stijnen T & Hokken-Koelega ACS (2008), Prediction model for adult height of small for gestational age children at the start of growth hormone treatment, Journal of Clinical Endocrinology and Metabolism 93(2).
- Leunissen RWJ, Oosterbeek P, Hol LKM, Hellingman AA, Stijnen T & Hokken-Koelega ACS (2008), Fat mass accumulation during childhood determines insulin sensitivity in early adulthood, Journal of Clinical Endocrinology and Metabolism 93(2).
- Hughes S, Keene O, Howitt N, Roes K, Ashby D, Beltangady M, Bird SM, Burton C, Buyse M, Day S, van Ewijk P, Fletcher C, Grieve AP, Guinot C, Hand DJ, Hemmings R, Holt D, Hothorn L, Jagers P, Keiding N, Korhonen P, Lesaffre E, Lewis JA, Molenberghs G, Neumann N, Olsen KJ, van Osta G, Pocock S, Rockhold F, Rossi A, Senn S, Stijnen T, Vaeth M, Wiklund SJ & Wolfram J (2008), European regulatory agencies should employ full time statisticians, British medical journal 336(7638).
- Aziz NA, van der Burg JMM, Landwehrmeyer GB, Brundin P, Stijnen T & Roos RAC (2008), Weight loss in Huntington's disease is related to the number of CAG repeats, Journal of Neurology, Neurosurgery and Psychiatry 79.
- Leunissen RWJ, Kerkhof GF, Stijnen T & Hokken-Koelega ACS (2008), Fat Mass and Apolipoprotein E Genotype Influence Serum Lipoprotein Levels in Early Adulthood, whereas Birth Size Does Not, Journal of Clinical Endocrinology and Metabolism 93(11): 4307-4314.
- Willemsen R, Leunissen R, Stijnen T & Hokken-Koelega A (2008), Insulin sensitivity in young adults born permature, Hormone Research 70: 25-26.
- Kilic E, Stijnen T & Luyten GPM (2008), Preenucleation radiotherapy, uveal melanoma, and competing risks - In reply, Archives of Ophthalmology -New Series- 126(4).
- Niel-Weise BS, Stijnen T & van den Broek PJ (2008), Anti-infective-treated central venous catheters for total parenteral nutrition or chemotherapy: a systematic review, Journal of Hospital Infection 69(2).
- Ghidey W, Stijnen T, Houwing-Duistermaat JJ, Heijmans BT, Beekman M, Westendorp RGJ, Slagboom PE & van Houwelingen HC (2008), Prediction models for SNP data, Annals of Human Genetics 72.
- Verhagen AP, de Vet HCW, Willemsen S & Stijnen T (2008), A meta-regression analysis shows no impact of design characteristics on outcome in trials on tension-type headaches, Journal of Clinical Epidemiology 61(8).
- Timman R, Bonke B, Stijnen T, Tibben A & Maat-Kievit A (2008), Estimating decreased risks for Huntington disease without a test, European Journal of Epidemiology 23(4).
- Ghidey W, Stijnen T, Houwing-Duistermaat J, Heijmans B, Beekman M, Westendorp R, Slagboom E & van Houwelingen HC (2008), Predicting a binary outcome using SNPs: a case study on prediction of longevity, Genetic Epidemiology 32(7).
- Hamza TH, van Houwelingen HC & Stijnen T (2008), The binomial distribution of meta-analysis was preferred to model within-study variability, Journal of Clinical Epidemiology 61(1).
- Ghidey W, Lesaffre E & Stijnen T (2007), Semi-parametric modelling of the distribution of the baseline risk in meta-analysis, Statistics in Medicine 26(30).
- Dehghan A, Kardys I, de Maat MPM, Uitterlinden AG, Sijbrands EJG, Bootsma AH, Stijnen T, Hofman A, Schram MT & Witteman JCM (2007), Genetic variation, C-reactive protein levels, and incidence of diabetes, Diabetes 56(3).
- Niel-Weise BS, Stijnen T & van den Broek PJ (2007), Anti-infective-treated central venous catheters: a systematic review of randomized controlled trials, Intensive Care Medicine 33(12).
- Bonke B, Tibben A, Lindhout D & Stijnen T (2006), Calculating risk changes after negative mutation test outcomes for autosomal dominant hereditary late-onset disorders, Heredity 96(3).
- Bonke B, Tibben A, Lindhout D, Clarke AJ & Stijnen T (2005), Genetic risk estimation by health care professionals - Reply, Medical Journal of Australia 182(11): 597-597.
- van Houwelingen HC, van de Velde CJH & Stijnen T (2005), Interim analysis on survival data: Its potential bias and how to repair it, Statistics in Medicine 24(18).
- Timman R, Stijnen T & Tibben A (2004), Methodology in longitudinal studies on psychological effects of predictive DNA testing: a review., Journal of Medical Genetics 41(7): e100.
- van Pareren YK, Keizer-Schrama SMPFD, Stijnen T, Sas TCJ, Jansen M, Otten BJ, Hoorweg-Nijman JJG, Vulsma T, Stokvis-Brantsma WH, Rouwe CW, Reeser HM, Gerver WJ, Gosen JJ, Rongen-Westerlaken C & Drop SLS (2003), Final height in girls with Turner syndrome after long-term growth hormone treatment in three dosages and low dose estrogens, Journal of Clinical Endocrinology and Metabolism 88(3).
- Houwing-Duistermaat JJ, Bijkerk C, Hsu L, Stijnen T, Slagboom EP & van Duijn CM (2003), A unified approach to modelling linkage to quantitative and qualitative traits, Annals of Human Genetics 67.
- van Houwelingen HC, Arends LR & Stijnen T (2002), Advanced methods in meta-analysis: multivariate approach and meta-regression, Statistics in Medicine 21(4).
- van Houwelingen HC, Arends LR & Stijnen T (2002), Advanced methods in meta-analysis: multivariate approach and meta-regression., Statistics in Medicine 21(4): 589-624.
- Bonke B, Tibben A, Lindhout D & Stijnen T (2002), Favourable mutation test outcomes for individuals at risk for Huntington disease change the perspectives of first-degree relatives, Human Genetics 111(3).
- Bijkerk, C.; Houwing-Duistermaat, J.J.; Meulenbelt, I.; Valkenburg, H.A.; Hofman, A.; Breedveld, F.C.; Pols, H.A.P.; Stijnen, T.; Dujin, C.M. van & Slagboom, P.E. (1998), The genetic influence on the occurrence of radiological osteoarthritis., Arthritis and Rheumatism 41(9): S145-S145.
- Van Houwelingen HC, Zwinderman KH & Stijnen T (1993), A bivariate approach to meta-analysis., Statistics in Medicine 12(24): 2273-84.
- Brouwer OF, Pieters MS, Edelbroek PM, Bakker AM, van Geel AA, Stijnen T, Jennekens-Schinkel A, Lanser JB & Peters AC (1992), Conventional and controlled release valproate in children with epilepsy: a cross-over study comparing plasma levels and cognitive performances., Epilepsy Research 13(3): 245-53.
- freelance statistisch adviseur
- lid van trials van Chiesi en Nutricia Research
- freelance statistisch adviseur
- cursus
- cursus