Robert Verpoorte
Professor emeritus of Pharmacognosy, in particular plant cell biotechnology
- Name
- Prof.dr. R. Verpoorte
- Telephone
- +31 71 527 4528
- verpoort@chem.leidenuniv.nl
- ORCID iD
- 0000-0001-6180-1424
Robert Verpoorte is Professor emeritus of Pharmacognosy, in particular plant cell biotechnology and specialised in natural deep eutectic solvents, applications and biological roles.
More information about Robert Verpoorte
News
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Rob Verpoorte receives prestigious pharmocognosy award -
These eleven Leiden Science researchers are among the most highly cited -
Fungi add flavour to vanilla -
Flower bulbs to treat Alzheimer's -
17 Leiden researchers on highly cited list
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14 Leiden researchers on highly cited list
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Leiden discovery leads to new ageing cream and chicken feed
Research
Over the years the natural products laboratory has studied various aspects of natural products. This included the isolation and identification biological active compounds, their biosynthesis and metabolic engineering of relevant biosynthetic pathways. In recent years the development of metabolomics and the natural deep eutectic solvents have been the major interests. The work resulted in more than 800 publications, 6 patents and 3 books. The research is widely cited and places him is among the 1% most cited authors in Clarivate, Web of Science (Cross-Field)(2018, 2019, 2020 and 2021). A citation analysis made by Stanford University placed the impact of his work on position 45 (out of 134,814 authors) in the field of chemistry (2020, 2021).
Brief biography
- Pharmacists degree (1972) and a PhD (1976) from Leiden.
- Lecturer at Leiden University 1976-1987, 1987-2011 professor and head of the department of Plant cell Biotechnology Pharmacognosy.
- Guest professor in London (UK), Uppsala (Sweden), Amiens (France), Reims (France), Seoul (Korea), Florence (Italy), Hong Kong, Taiwan, and Hilo (USA).
- From 1992-1998 he was Vice-Chairman and Chairman of the committee of the Phytochemical Society of Europe (PSE).
- Since May 2011 he is professor Emeritus at Leiden University.
Grants & prizes
- 2004 Honorary Doctorate University of Amiens, France
- 2007 Phytochemistry Society of Europe Medal
- 2012 Honorary Doctorate University of Uppsala, Sweden
- 2015 Honorary professor Hong Kong Baptist University 2015
- 2015 Gusi Peace Prize in Manila, The Philippines
- 2017 Egon Stahl Medal in Gold by the International Society of Medicinal Plants and Natural Products Research
- 2017 Qihuang International Prize China Association of Chinese Medicine
- Among the 1% Highly Cited Researchers 2018, 2019 and 2020 (Cross-Field)(Web of Science, Clarivate Analytics)
- Among the 2% top scientists in the world in a recent Stanford study (2020, 2021), and based on this citation analysis his impact ranks on position 45 worldwide in the field of Chemistry (out of 134,814)
Other mentions
- Editor in Chief of Phytochemistry Reviews (IF2019 4.587) since 2001
- Executive Editor Biotechnology Letters (IF2019 1.982) since 2006
- Editor in Chief Journal od Ethnopharmacology (IF2020 4.275) 2003-2016
Professor emeritus of Pharmacognosy, in particular plant cell biotechnology
- Science
- Instituut Biologie Leiden
- IBL Plant Sciences
- Al Fuhaid L., Nava-Ocampo M.F., Bucs S.S., Verpoorte R., Choi Y.H., Witkamp G.J. & Farinha A.S.F. (2023), Crystallization and time-dependent changes in betaine-urea-water natural deep eutectic solvents, Journal of Molecular Liquids 387: 122718.
- Verpoorte R., Witkamp G.-J. & Choi Y.H. (2022), Preface: natural deep eutectic solvents: A third liquid phase in living organisms? Discovery, theory, biology and applications, Advances in Botanical Research 97: xv-xxii.
- Nava-Ocampo M.F., Al Fuhaid K., Santana A., Bucs S.S., Verpoorte R., Choi Y.H., Witkamp G.J., Vrouwenwelder J.S. & Farinha A.S.F. (2021), Structural properties and stability of the betaine-urea natural deep eutectic solvents, Journal of Molecular Liquids 343: 117655.
- Nava-Ocampo M.F., Al Fuhaid L., Verpoorte R., Choi Y.H., Loosdrecht M.C.M. van, Vrouwenvelder J.S., Witkamp G.J., Farinha A.S.F. & Bucs S.S. (2021), Natural deep eutectic solvents as biofilm structural breakers, Water Research 201: 117323.
- Mustafa N.R., Spelbos V.S., Witkamp G.-J., Verpoorte R. & Choi Y.H. (2021), Solubility and stability of some pharmaceuticals in natural deep eutectic solvents-based formulation, Molecules 26(9): 2645.
- Salome Abarca L.F., Godevac D., Kim M.S., Hwang G.-S., Parc S.C., Jang Y.P., Hondel C.A.M.J.J. van der, Verpoorte R., Klinkhamer P.G.L. & Choi Y.H. (2021), Latex metabolome of Euphorbia species: geographical and inter-species variation and its proposed role in plant defense against herbivores and pathogens, Journal of Chemical Ecology 47: 564–576.
- Dai Y., Varypataki E.M., Golovina E.A., Jiskoot W., Witkamp G.-J., Choi Y.H. & Verpoorte R. (2021), Natural deep eutectic solvents in plants and plant cells: In vitro evidence for their possible functions, Advances in Botanical Research 97: 159-184.
- Vanda H., Mustafa N.R., Verpoorte R., Klinkhamer P.G.L. & Choi Y.H. (2021), Natural deep eutectic solvents present in plant exudates? A case study on the saps of Droseraspecies, Advances in Botanical Research 97: 253-269.
- Dai Y., Choi Y.H. & Verpoorte R. (2021), Honey in traditional Chinese medicine: A guide to future applications of NADES to medicines, Advances in Botanical Research 97: 361-384.
- Bouguellid G., Russo C., Lavorgna M., Piscitelli C., Ayouni K., Wilson E., Kim H.K., Verpoorte R., Choi Y.H., Kilani-Atmani D., Atmani D. & Isidori M. (2020), Antimutagenic, antigenotoxic and antiproliferative activities of Fraxinus angustifolia Vahl. leaves and stem bark extracts and their phytochemical composition, PLoS ONE 15(4): e0230690.
- Oomen W.W., Begines P., Mustafa N.R., Wilson E.G., Verpoorte R. & Choi Y.H. (2020), Natural deep eutectic solvent extraction of flavonoids of Scutellaria baicalensis as a replacement for conventional organic solvents, Molecules 25(3): 617.
- Mišan A., Nađpal J., Stupar A., Pojić M., Mandić A., Verpoorte R. & Choi Y.H. (2019), The perspectives of natural deep eutectic solvents in agri-food sector, Critical Reviews in Food Science and Nutricion 60(15): 2564-2592.
- Rozema E., Kierszniowska S., Almog-Gabai O., Wilson E.G., Choi Y.H., Verpoorte R., Hamo R., Chalifa-Caspi V., Assaraf Y.G. & Lubzens E. (2019), Metabolomics reveals novel insight on dormancy of aquatic invertebrate encysted embryos, Scientific Reports 9: 8878.
- López-Gresa M.P., Payá C., Rodrigo I., Bellés J.M., Barceló S., Choi Y.H., Verpoorte R. & Lisón P. (2019), Effect of benzothiadiazole on the metabolome of tomato plants infected by citrus exocortis viroid, Viruses 11(5): 437.
- Choi Y.H. & Verpoorte R. (2019), Green solvents for the extraction of bioactive compounds from natural products: from supercritical fluid extraction to ionic liquids and deep eutectic solvents, Current Opinion in Food Science 26: 87-93.
- Ma Y., Li P., Willot S.J.P., Zhang W., Ribitsch D., Choi Y.H., Verpoorte R., Zhang T., Hollmann F. & Wang Y. (2019), Natural deep eutectic solvents as multifuntional media for the valorization of agricultural wastes, ChemSusChem 12(7): 1310-1315.
- McAlpine J.B., Chen S.N., Kutateladze A., MacMillan J.B., Appendino G., Barison A., Beniddir M.A., Biavatti M.W., Bluml S., Boufridi A., Butler M.S., Capon R.J., Choi Y.H., Coppage D., Crews P., Crimmins M.T., Csete M., Dewapriya P., Egan J.M., Garson M.J., Genta-Jouve G., Gerwick W.H., Gross H., Harper M.K., Hermanto P., Hook J.M., Hunter L., Jeannerat D., Ji N.Y., Johnson T.A., Kingston D.G.I., Koshino H., Lee H.W., Lewin G., Li J., Linington R.G., Liu M., McPhail K.L., Molinski T.F., Moore B.S., Nam J.W., Neupane R.P., Niemitz M., Nuzilard J.M., Oberlies N.H., Ocampos F.M.M., Pan G., Quinn R.J., Reddy S.D., Renault J.H., Rivera-Chavez J., Robien W., Saunders C.M., Schmidt T.J., Seger C., Shen B., Steinbeck C., Stuppner H., Sturm S., Tagliatatela-Scafati O., Tantillo D.J., Verpoorte R., Wang B.G., Williams C.M., Williams P.G., Wist J., Yue J.M., Zhang C., Xu Z., Simmler C., Lankin D.C., Bisson J. & Pauli G.F. (2019), The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research, Natural Product Reports 36(1): 35-107.
- Verpoorte R., Kim H.K. & Choi Y.H. (2018), Synergy: easier to say than to prove, Synergy 7: 34-35.
- Gonzalez C.G., Mustafa N.R., Wilson E.G., Verpoorte R. & Choi Y.H. (2018), Application of natural deep eutectic solvents for the "green" extraction of vanillin from vanilla pods, Flavour and Fragrance Journal 33(1): 91-96.
- Liu X., Ahlgren S., Korthout H., Salomé Abarca L.F., Bayona Maldonado L.M., Verpoorte R. & Choi Y.H. (2018), Broad range chemical profiling of natural deep eutectic solvent extracts using a high performance thin layer chromatography-based method, Journal of Chromatography A 1532: 198-207.
- Choi Y.H. (2018), Special issue dedicated to Prof. Dr. Robert Verpoorte, Planta Medica 84(12/13): 833.
- Hennivanda H., Wilson E.G., Verpoorte R. & Choi Y.H. (2018), Green solvents from ionic liquids and deep eutectic solvents to natural deep eutectic solvents, Comptes Rendus Chimie 21(6): 628-638.
- Saiman M.Z., Miettinen K., Mustafa N.R., Choi Y.H., Verpoorte R. & Schulte A.E. (2018), Metabolic alteration of Catharanthus roseus cell suspension cultures overexpressing geraniol synthase in the plastids or cytosol, Plant Cell, Tissue and Organ Culture 134(1): 41-53.
- Khoyratty S., Choi Y.H., Dupont J., Verpoorte R. & Kodja H. (2017), Host and guest: vanilla inhabited by endophytes. In: Mérillon J.M. & Ramawat K.G. (Eds.), Fungal netabolites. Reference Series in Phytochemistry ((RSP)). Cham: Springer International Publishing. 191-217.
- Ralha de Abreu A.C., Coqueiro A., Sultan A.R., Lemmens N., Kim H.K., Verpoorte R., Warmel W.J.B. van, Simões M. & Choi Y.H. (2017), Looking to nature for a new concept in antimicrobial treatments: isoflavonoids from Cytisus striatus as antibiotic adjuvants against MRSA, Scientific Reports 7: 3777.
- Zaluski D., Olech M., Kuzniewski R., Verpoorte R., Nowak R. & Smolarz H.D. (2017), LC-ESI-MS/MS profiling of phenolics from Eleutherococcus spp. inflorescences, structure-activity relationship as antioxidants, inhibitors of hyaluronidase and acetylcholinesterase, Saudi Pharmaceutical Journal 25(5): 734-743.
- Chao J., Dai Y., Verpoorte R., Lam W., Cheng Yung-Chi, Pao Li-Heng, Zhang W. & Chen S. (2017), Major achievements of evidence-based traditional Chinese medicine in treating major diseases, Biochemical Pharmacology 139: 94-104.
- Verpoorte R. (2017), New times for traditional medicine research, Journal of Ethnopharmacology 197: 1-1.
- Zaluski D., Olech M., Verpoorte R., Khan Inamullah, Kuzniewski R. & Nowak R. (2017), Phytoconstituents and Nutritional Properties of the Fruits of Eleutherococcus divaricatus and Eleutherococcus sessiliflorus: A Study of Non-European Species Cultivated in Poland, Oxidative Medicine and Cellular Longevity 2017: 8374295.
- Leonti M. & Verpoorte R. (2017), Traditional Mediterranean and European herbal medicines, Journal of Ethnopharmacology 199: 161-167.
- Buenz E.J., Verpoorte R. & Bauer B.A. (2017), The ethnopharmacologic contribution to bioprospecting natural products, Annual Review of Pharmacology and Toxicology 58: 509-530.
- Pan Q., Saiman M.Z., Mustafa N.R., Verpoorte R. & Tang K. (2016), A simple and rapid HPLC-DAD method for simultaneously monitoring the accumulation of alkaloids and precursors in different parts and different developmental stages of Catharanthus roseus plants, Journal of Chromatography B 1014: 10-16.
- Dai Y., Rozema E., Verpoorte R. & Choi Y.H. (2016), Application of natural deep eutectic solvents to the extraction of anthocyanins from Catharanthus roseus with high extractability and stability replacing conventional organic solvent, Journal of Chromatography A 1434: 50-56.
- Schilthuizen M., Santos Pimenta L.P., Lammers Y., Steenbergen P.J., Flohil M., Beveridge N.G., Duijn P.T. van, Meulblok M.M., Sosef N., Ven R. van de, Werring R., Beentjes K.K., Meijer K., Vos R.A., Vrieling K., Gravendeel B., Choi Y.H., Verpoorte R., Smit C. & Beukeboom L.W. (2016), Incorporation of an invasive plant into a native insect herbivore food web, PeerJ 4: e1954.
- Akhtar M.T., Mushtaq M.Y., Verpoorte R., Richardson M.K. & Choi Y.H. (2016), Zebrafish as a model for systems medicine R&D: rethinking the metabolic effects of carrier solvents and culture buffers determined by (1)H NMR metabolomics, OMICS: A Journal of Integrative Biology 20(1): 42-52.
- Ayouni K., Berboucha M., Kim H.K., Atmani D., Verpoorte R. & Choi Y.H. (2016), Metabolomic tool to identify antioxidant compounds of Fraxinus angustifolia leaf and stem bark extracts, Industrial Crops and Products 88: 65-77.
- Coqueiro A., Choi Y.H., Verpoorte R., Gupta K.B.S.S., Mieri M. de, Hamburger M., Young M.C.M., Stapleton P., Gibbons S. & Bolzani V.D.S. (2016), Antistaphylococcal prenylated acylphloroglucinol and xanthones from Kielmeyera variabilis (Clusiaceae), Journal of Natural Products 79(3): 470-476.
- Akhtar M.T., Mushtaq M.Y., Verpoorte R., Richardson M.K. & Choi Y.H. (2016), Metabolic effects of cannabinoids in zebrafisch (Danio Rerio) embryos determined by 1HNMR metabolomics, Metabolomics 12(3): 44.
- Dai Y., Witkamp G.J., Verpoorte R. & Choi Y.H. (2015), Tailoring properties of natural deep eutectic solvents with water to facilitate their applications, Food Chemistry 187: 14-19.
- Khoyratty S., Dupont J., Lacoste S., Palama T.L., Choi Y.H., Kim H.K., Payet B., Grisoni M., Fouillaud M., Verpoorte R. & Kodja H. (2015), Fungal endophytes of Vanilla planifolia across Réunion Island: isolation, distribution and biotransformation, BMC Plant Biology 15: 142.
- Rozema E., Dam A.D. van, Sips H.C.M., Verpoorte R., Meijer O.C., Kooijman S. & Choi Y.H. (2015), Extending pharmacological dose-response curves for salsalate with natural deep eutectic solvents, RSC Advances 5(75): 61398-61401.
- Mohd Zuwairi Bin Saiman M., Mustafa N.R., Pomahacova B., Verberne M.C., Verpoorte R., Choi Y.H. & Schulte A.E. (2015), Erratum to: Analysis of metabolites in the terpenoid pathway of Catharanthus roseus cell suspensions, Plant Cell, Tissue and Organ Culture 122(1): 257.
- Mohd Zuwairi Bin Saiman M., Mustafa N.R., Choi Y.H., Verpoorte R. & Schulte A.E. (2015), Metabolic alterations and distribution of five-carbon precursors in jasmonic acid-elicited Catharanthus roseus cell suspension cultures, Plant Cell, Tissue and Organ Culture 122: 351-362.
- Ali K., Verpoorte R., Wilson E.G. & Choi Y.H. (2015), Chemical Characterization of Marine Organisms Using e Metabolomic Approach. In: Baker B.J. (Ed.), Marine Biomedicine: From beach to Bedside. Boca Raton FL USA: CRC press. 23-42.
- Zheng L., Wang M., Ibarra Estrada E., Wu C., Wilson E.G., Verpoorte R., Klinkhamer P.G.L. & Choi Y.H. (2015), Investigation of chemomarkers of astragali radix of different ages and geographical origin by NMR profiling, Molecules 20(2): 3389-3405.
- Pan Q., Mustafa N.R., Tang K., Choi Y.H. & Verpoorte R. (2015), Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolites, Phytochemistry Reviews 15: 221-250.
- Coqueiro A. & Verpoorte R. (2015), Alkaloids. In: Worsfold P., Poole C., Townshend A. & Miró F. (Eds.), Encyclopedia of Analytical Science . Reference Module in Chemistry, Molecular Sciences and Chemical Engineering no. 1: Elsevier. 77-84.
- Klinkhamer P.G.L., Nuringtyas T.R., Verpoorte R., Oers M.M. & leiss K.A. (2014), Toxicity of Pyrrolizidine Alkaloids to Spodoptera exigua using insect cell lines and injection bioassays, Jounal of Chemical Ecology 40(6): 609 -616.
- Miettinen K.A., Dong L., Navrot N., Schneider T., Burlat V., Pollier J., Woittiez L., Krol S. van der, Lugan R., Ilc T., Verpoorte R., Oksman-Caldentey K.M., Martinoia E., Bouwmeester H., Goossens A., Memelink J. & Werck-Reichhart D. (2014), The seco-iridoid pathway from Catharanthus roseus, Nature Communications 5: 3606.
- Scognamiglio M., Fiumano V., D'Abrosca B., Esposito A., Choi Y.H., Verpoorte R. & Fiorentino A. (2014), Chemical interactions between plants in Mediterranean vegetation: the influence of selected plant extracts on Aegilops geniculata metabolome, Phytochemistry 106: 69-85.
- Coqueiro A., Lee L.W., Silva Bolzani V. de, Verpoorte R. & Choi Y.H. (2014), Development of a temperature-pressure controlled extraction method for the alkaloids of Erythrina mulungu, Planta Medica 80(16): 1457-1458.
- Mushtaq M.Y., Marçal R.M., Champagne D.L., Kooy F. van der, Verpoorte R. & Choi Y.H. (2014), Effect of acute stresses on Zebra Fish (Danio rerio) metabolome measured by NMR-based metabolomics, Planta Medica 80(14): 1227-1233.
- Rachmania O., Choi Y.H., Arruabarrena I., Vermeulen B., Spronsen J. van, Verpoorte R. & Witkamp G.J. (2014), Environmentally benign supercritical CO2 extraction of galanthamine from floricultural crop waste of Narcissus pseudonarcissus, Journal of Supercritical Fluids 93: 7-19.
- Mushtaq M.Y., Choi Y.H., Verpoorte R. & Wilson E.G. (2014), Extraction for metabolomics: access to the metabolome, Phytochemical Analysis 25(4): 291-306.
- Yuliana N Rosa D Budijanto S Verpoorte R Choi Y (2014), Identification of adenosine A1 receptor ligands from Morus alba L. stem bark by NMR metabolomics approach, International Food Research Journal 21(3): 1103-1107.
- Jahangir M., Abdel-Farid I., Mahmood Z., Jamil M., Rey P., Choi Y.H. & Verpoorte R. (2014), Metabolomic approach: postharvest storage stability of red radish ( Raphanus sativus L.), Journal of the Chemical Society of Pakistan 36(5): 931-938.
- Choi Y.H. & Verpoorte R. (2014), Metabolomics: what you see is what you extract, Phytochemical Analysis 25(4): 289-290.
- Verpoorte R. & Choi Y.H. (Eds.) (2014), Special Issue in Phytochemical Analysis, Pre-analytical methods in metabolomics: sample preparation and extraction: Wiley.
- Iqbal M., Verpoorte R., Korthout H.A.A.J. & Mustafa N.R. (2013), Phytochemicals as a potential source for TNF-a inhibitors, 12: 65-93.
- Mushtaq M.Y., Verpoorte R. & Kim H.K. (2013), Zebrafish as a model for systems biology, Biotechnology and Genetic Engineering Reviews : .
- Charoonratana T., Wungsintaweekul J., Keawpradub N. & Verpoorte R. (2013), Molecular cloning and expression of tryptophan decarboxylase from Mitragyna speciosa, Acta Physiologiae Plantarum 35: 2611-2621.
- Antonio C., Mustafa N.R., Osorio S., Tohge T., Giavalisco P., Willmitzer L., Rischer H., Oksman-Caldentey K.M., Verpoorte R. & Fernie A.R. (2013), Analysis of the interface between primary and secondary metabolism in Catharanthus roseus cell cultures using 13C-stable isotope feeding and coupled mass spectrometry, Molecular Plant 6: 581-584.
- Toyang N.J., Ateh E.N., Davis H., Tane P., Sondengam L.B., Bryant J. & Verpoorte R. (2013), In vivo antiprostate tumor potential of Vernonia guineensis Benth. (Asteraceae) tuber extract (VGDE) and the cytotoxicity of its major compound pentaisovaleryl sucrose, 150: 724-728.
- Pan Q., Dai Y., Nuringtyas T.R., Mustafa N.R., Schulte A.E., Verpoorte R. & Choi Y.H. (2013), Investigation of the chemomarkers correlated with flower colour in different organs of Catharanthus roseus using NMR‐based metabolomics, Phytochemical Analysis 25(1): 66-74.
- Lubbe A., Ali K., Verpoorte R. & Choi Y.H. (2013), NMR-based metabolomics analysis. In: Lämmerhofer M. & Weckwerth W. (Eds.), Metabolomics in Practice: Successful Strategies to Generate and Analyze Metabolic Data. Weinheim: Wiley-VCH. 209-238.
- Zárate R., El Jaber-Vazdekis N. & Verpoorte R. (2013), Metabolic Engineering of Plant Cellular Metabolism: Methodologies, Advances, and Future Directions. In: , Biotechnology for Medicinal Plants. Heidelberg: Springer-Verlag. 259-393.
- Sar S van der., Kim H.K., Meissner A., Verpoorte R. & Choi Y.H. (2013), Nuclear magnetic resonance spectroscopy for plant metabolite profiling. In: Weckwerth W. & Kahl G. (Eds.), The Handbook of Plant Metabolomics. Weinheim: Wiley-VCH. 57-76.
- Lubbe A., Gude H., Verpoorte R. & Choi Y.H. (2013), Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton, Phytochemistry 88: 43-53.
- Dai Y., Spronsen J. van, Witkamp G.J., Verpoorte R. & Choi Y.H. (2013), Natural deep eutectic solvents as new potential media for green technology, Analytica Chimica Acta 766: 61-68.
- Ali K., Iqbal M., Yuliana N.D., Lee Y.J., Park S., Han S., Lee J.W., Lee H.S., Verpoorte R. & Choi Y.H. (2013), Identification of bioactive metabolites against adenosine A1 receptor using NMR-based metabolomics, Metabolomics 9(4): 778-785.
- D’Abrosca B., Scognamiglio M., Fiumano V., Esposito A., Cho Y.H., Verpoorte R. & Fiorentino A. (2013), Plant bioassay to assess the effects of allelochemicals on the metabolome of the target species Aegilops geniculata by a NMR-based approach, Phytochemistry 93: 37-40.
- Charoonratana T., Pathompak P., Keawpradub H., Georgiev M.I., Choi Y.H., Verpoorte R. & Wungsintaweekul J. (2013), Limitation of mitragynine biosynthesis in mitragyna speciosa (Roxb.) Korth. through tryptamine availability, Zeitschrift fuer Naturforschung C : A Journal of Biosciences 68(9-10): 394-405.
- Ali K., Iqbal M., Fortes A.M., Pais M.S., Korthout H.A.A.J., Verpoorte R. & Choi Y.H. (2013), Red wines attenuate TNFα production in human histiocytic lymphoma cell line: An NMR spectroscopy and chemometrics based study, Food Chemistry 141: 3124-3130.
- Toyang N.J. & Verpoorte R. (2013), A Review of the Medicinal Potentials of Plants of the Genus Vernonia, 146: 681–723.
- Kim H.K., Choi Y.H. & Verpoorte R. (2013), Profiling the jasmonic acid responses by nuclear magnetic resonance-based metabolomics, Methods in Molecular Biology : 267-275.
- Toyang N.J., Krause M., Fairhurst R., Tane P., Bryant J. & Verpoorte R. (2013), Antiplasmodial activity of sesquiterpene lactones and a sucrose ester from Vernonia guineensis Benth, 147: 618-621.
- Dai L.Y., Witkamp G.J., Verpoorte R. & Choi Y.H. (2013), Natural deep eutectic solvents as a new extraction media for phenolic metabolites in Carthamus tinctorius, Analytical Chemistry 85(13): 6272-6278.
- Pimenta L.P.S., Kim H.K., Verpoorte R. & Choi Y.H. (2013), NMR-based metabolomics: a probe to utilize biodiversity. In: Rössner U. & Dias D.A. (Eds.), Metabolomics Tools for Natural Product Discovery. Methods in Molecular Biology. Totowa, NJ: Humana Press. 117-127.
- Wahyuni D.S., Van der Kooy F., Klinkhamer P.G.L., Verpoorte R. & Leiss K.A. (2013), The use of bio-guided fractionation to explore the use of leftover biomass in Dutch flower bulb production as allelochemicals against weeds, Molecules 18: 4510-4525.
- Goldhaber Pasillas G.D., Choi Y.H. & Verpoorte R. (2013), New methods of analysis and investigation of terpenoid indole alkaloids, Advances in Botanical Research 68: 233-272.
- Akhtar M.T., Ali S., Rashidi H., Kooy F. van der, Verpoorte R. & Richardson M.K. (2013), Developmental Effects of Cannabinoids on Zebrafish Larvae, Zebrafish 10(3): 283-293.
- Yuliana N.D., Korthout H., Wijaya C.H., Kim H.K. & Verpoorte R. (2013), Plant-Derived Food Ingredients for Stimulation of Energy Expenditure, Critical Reviews in Food Science and Nutricion 54: 373-388.
- Dai Y., Spronsen J. van, Witkamp G.J., Verpoorte R. & Choi Y.H. (2013), Ionic Liquids and Deep Eutectic Solvents in Natural Products Research: Mixtures of Solids as Extraction Solvents, Journal of Natural Products 76(11): 2162-2173.
- Yuliana N.D., Jahangir M., Verpoorte R. & Choi Y.H. (2013), Metabolomics for the rapid dereplication of bioactive compounds from natural sources, Phytochemistry Reviews 12(2): 293-304.
- Georgiev M.I., Ivanovska N., Alipieva K., Dimitrova P. & Verpoorte R. (2013), Harpagoside: from Kalahari Desert to pharmacy shelf, Phytochemistry 79: 8-15.
- Leiss K.A., Cristofori R., Steenis R. van, Verpoorte R. & Klinkhamer P.G.L. (2013), An eco-metabolomic study of host plant resistance to Western flower thrips in cultivated, biofortified and wild carrots, Phytochemistry 93: 63-70.
- Toyang N.J., Wabo H.K., Ateh E.N. & Verpoorte R. (2013), Cytotoxic sesquiterpene lactones from the leaves of Vernonia guinensis Benth, 146: 552-556.
- Ahmed I.S., El Tobami E.S., Almagboul A.Z. & Verpoorte R. (2012), Characterization of anti-microbial compounds isolated from Mangifera indica L see kernel, University of Africa Journal of Sciences 2: 77-91.
- Ali K., Maltese F., Figueiredo A., Rex M., Fortes A.M., Zyprian E., Pais M.S., Verpoorte R. & Choi Y.H. (2012), Alterations in grapevine leaf metabolism upon inoculation with Plasmopara viticola in different time-points, Plant Science 191-192: 100-107.
- Lubbe A., Verpoorte R. & Choi Y.H. (2012), Effects of fungicides on galanthamine and metabolite profiles in Narcissus bulbs, Plant Physiology and Biochemistry 58(11): 116-123.
- Jahangir M. Abdel-Farid I.B. Simoh S. Kim H.K. Verpoorte R. Choi Y.H. (2012), Investigation of Brassica biochemical status by NMR-based metabolomics, Acta Horticulturae 936: 163-172.
- Flores-Sanchez I.J., Choi Y.H. & Verpoorte R. (2012), Metabolite analysis of Cannabis sativa L. by NMR spectroscopy. In: Kaufmann M. & Klinger C. (Eds.), Functional genomics : methods and protocols. Methods in Molecular Biology no. 815. New York, N.Y., U.S.A.: Springer. 363-376.
- Gerardi C., Blando F., Mulé G., Maltese F., Ali K. & Verpoorte R. (2012), Metabolic characterization of Prunus cerasus L. and Prunus mahaleb L. fruit. In: D'Onghia A., Batlle I., Caruso T., Corelli Grappadelli L., Callesen O. & Bonany J. (Eds.), XXVIII International Horticultural Congress on Science and Horticulture for People (IHC2010): International Symposium on the Challenge for a Sustainable Production, Protection and Consumption of Mediterranean Fruits and Nuts.. Lisbon, Portugal 361-368.
- Ali K., Iqbal M., Korthout H.A.A.J., Maltese F., Fortes A.M., Pais M.S., Verpoorte R. & Choi Y.H. (2012), NMR spectroscopy and chemometrics as a tool for anti-TNFa activity screening in crude extracts of grapes and other berries, METABOLOMICS 8: 1148-1162.
- Pan Q., Wang Q., Yuan F., Xing S., Zhao J., Choi Y.H., Verpoorte R., Tian Y., Wang G. & Tang K. (2012), Overexpression of ORCA3 and G10H in Catharanthus roseus plants regulated alkaloid biosynthesis and metabolism revealed by NMR-metabolomics, PLoS ONE 7(8): e43038.
- Verpoorte R. (2012), Good Practices: The basis for evidence-based medicines, 140: 455-457.
- Agnolet S., Verpoorte R. & Staerk D. (2012), Comprehensive analysis of commercial willow bark extracts by new technology platform: Combined use of metabolomics, high-performance liquid chromatography-solid-phase-extraction-nuclear magnetic resonance, Journal of Chromatography A 1262: 130-137.
- Qin X., Liu N.Q., Li Z., Liu X., Choi Y.H. & Verpoorte R. (2012), Metabolic fingerprinting by 1HNMR for discrimination of the two species used as radix bupleuri, Planta Medica 78(9): 926-933.
- Palama T.L., Grisoni M., Fock-Bastide I., Jade K., Barter L., Choi Y.H., Verpoorte R. & Kodja H. (2012), Metabolome of Vanilla planifolia (Orchidaceae) and related species under Cymbidium mosaic virus (CymMV) infection, Plant Physiology and Biochemistry 60: 25-34.
- Lopez-Gresa M.P., Lison P., Kim H.K., Choi Y.H., Verpoorte R., Rodrigo I., Conejero V. & Belles J.M. (2012), Metabolic fingerprinting of Tomato Mosaic Virus infected Solanum lycopersicum, Journal of Plant Physiology 169(16): 1586-1596.
- Sharma A., Cardoso-Taketa A., Choi Y.H., Verpoorte R. & Villarreal M.L. (2012), A comparison on the metabolic profiling of the Mexican anxiolytic and sedative plant Galphimia glauca four years later, Journal of Ethnopharmacology 141(3): 964-974.
- Akhtar M.T., Ali S., Verpoorte R. & Richardson M.K. (2012), Behavioral effects of cannabinoids on zebrafish larvae, Planta Medica 78(11): 1100-1100.
- Nuringtyas T.R., Choi Y.H., Verpoorte R., Klinkhamer P.G.L. & Leiss K.A. (2012), Differential tissue distribution of metabolites in Jacobaea vulgaris, Jacobaea aquatica and their crosses, Phytochemistry 78: 89-97.
- Mohd Zuwairi Bin Saiman M., Mustafa N.R., Schulte A.E., Verpoorte R. & Choi Y.H. (2012), Induction, characterization, and NMR-based metabolic profiling of adventitious root cultures from leaf explants of Gynura procumbens, Plant Cell, Tissue and Organ Culture 109: 465-475.
- El-Seedi H.R., El-Said A., Khalifa S., Goeransson U., Bohlin L., Borg-Karlson A.-K. & Verpoorte R. (2012), Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids, Journal of Agricultural and Food Chemistry 60: 10877-10895.
- Verpoorte R. (2012), Primary data are the basis of all science! Editorial, 139: 683-684.
- Yuliana N.D., Khatib A., Verpoorte R. & Choi Y.H. (2011), Comprehensive extraction integrated with NMR metabolomics: a new way of bioactivity screening methods for plants, adenosine A1 receptor binding compounds in Orthosiphon stamineus Benth, Analytical Chemistry 83(17): 6902-6906.
- Chan W.T., Choi Y.H., Heijden R. van der, Lee M.S., Lin M.K., Kong H., Kim H.K., Verpoorte R., Hankemeier T. & Greef J. van der (2011), Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa Roots, Chemical and pharmaceutical bulletin 59: 546.
- Kooy F. van der & Verpoorte R. (2011), The Content of Artemisinin in the Artemisia annua Tea Infusion, Planta Medica 77: 1754.
- Lubbe A., Choi Y.H., Vreeburg P. & Verpoorte R. (2011), Effect of fertilizers on galanthamine and metabolite profiles in Narcissus bulbs by 1H NMR, Journal of Agricultural and Food Chemistry 59(7): 3155-3161.
- Ali K., Maltese F., Fortes A.M., Pais M.S., Verpoorte R. & Choi Y.H. (2011), Pre-analytical method for NMR-based grape metabolic fingerprinting and chemometrics, Analytica Chimica Acta 703: 179.
- Lubbe A. & Verpoorte R. (2011), Cultivation of medicinal and aromatic for specialty industrial materials, Onbekend 59: 785.
- Palama T.L., Khatib A., Choi Y.H., Come B., Fock I., Verpoorte R. & Kodja H. (2011), Metabolic Characterization of Green Pods from Vanilla planifolia Accessions Grown in La Réunion, Onbekend 72: 258.
- Dao T.T., Linthorst H.J.M. & Verpoorte R. (2011), Chalcone synthase and its functions in plant resistance, 10: 397-412.
- Georgiev M., Ali K., Alipieva K., Verpoorte R. & Choi Y.H. (2011), Metabolic differentiations and classification of Verbascum species by NMR-based metabolomics, Phytochemistry 72(16): 2045-2051.
- Kim H.K., Choi Y.H. & Verpoorte R. (2011), NMR-based plant metabolomics: where do we stand, where do we go?, Trends in Biotechnology 29: 267.
- Namdeo A., Sharma A., Yadav K., Gawande R., Mahadik K., Lopez-Gresa M., Kim H.K., Choi Y.H. & Verpoorte R. (2011), Metabolic characterization of Withania somnifera from different regions of India using NMR spectroscopy, Planta Medica 77(17): 1958-1964.
- Spronsen J. van, Witkamp G.-J., Hollman F., Choi Y.H. & Verpoorte R. (15 December 2011), Process for extracting materials from biological material (patent no. PCT/NL2011/050407). Requested on 15 December 2011. [patent].
- Yuliana N.D., Khatib A., Choi Y.H. & Verpoorte R. (2011), Metabolomics for bioactivity assessment of natural products, Phytotherapy Research 25(2): 157-169.
- Yuliana N.D., Jahangir M., Korthout H.A., Choi Y.H., Kim H.K. & Verpoorte R. (2011), Comprehensive review on herbal medicine for energy intake suppression, Obesity Reviews 12(7): 499-514.
- Mustafa N.R., Winder W. de, Iren F. van & Verpoorte R. (2011), Initiation, growth and cryopreservation of plant cell suspension cultures, Nature Physics 6: 715-742.
- Quintana N., Kooy F. van der, Rhee M.D. van de, Voshol G.P. & Verpoorte R. (2011), Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering, Applied Microbiology and Biotechnology 91: 471.
- Choi Y.H., Spronsen J. van, Dai Y., Verberne M., Hollmann F., Arends I.W.C.E., Witkamp G.-J. & Verpoorte R. (2011), Are natural deep eutectic solvents the missing link in understanding cellular metabolism and physiology?, Plant Physiology 156(4): 1701-1705.
- Yuliana N.D., Iqbal M., Jahangir M., Wijaya C.H., Korthout H.A., Kottenhagen M., Kim H.K. & Verpoorte R. (2011), Screening of selected Asian spices for anti obesity-related bioactivities, Food Chemistry 126: 1724-1729.
- Fortes A.M., Agudelo-Romero P., Silva M.S., Ali K., Sousa L., Maltese F., Choi Y.H., Grimplet J., Martinez-Zapater J.M. & Verpoorte R. (2011), Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening, BMC Plant Biology 11: 149.
- Perrotin-Brunel H., Buijs W., Spronsen J. van, Roosmalen M.J.E. van, Peters C.J., Verpoorte R. & Witkamp G.-J. (2011), Decarboxylation of Delta-9-tetrahydrocannabinol: kinetics and molecular modeling, Onbekend 987: 67-73.
- Maltese F., Ali K., Toepfer R., Choi Y.H. & Verpoorte R. (2011), Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses, Journal of Biomolecular NMR 49: 255-266.
- Abreu I.N., Choi Y.H., Sawaya A.C.H.F., Eberlin M.N., Mazzafera P. & Verpoorte R. (2011), Metabolic alterations in different developmental stages of Pilocarpus microphyllus, Planta Medica 77(3): 293-300.
- Fortes A.M., Pais M.S., Choi Y.H. & Verpoorte R. (2011), Monitoring biochemical changes during grape berry development in Portuguese cultivars by NMR spectroscopy, Food Chemistry 124: 1760-1769.
- Leiss K.A., Choi Y.H., Verpoorte R. & Klinkhamer P.G.L. (2011), An overview of NMR-based metabolomics to identify secondary plant compounds involved in host plant resistance, Phytochemistry Reviews 10(2): 205-216.
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- Verpoorte R., Choi Y.H. & Kim H.K. (2010), Metabolomics: will it stay?, Phytochemical Analysis 21(1): 2-3.
- Kim H.K., Saifullah S.K., Wilson E., Prat Kricun S.D., Meissner A., Goraler S., Deelder A.M., Choi Y.H. & Verpoorte R. (2010), Metabolic classification of South-American Ilex Species by NMR-based metabolomics, Phytochemistry 71(7): 773-784.
- Abdel-Farid B., Jahangir M., Mustafa N.R., Dam N. van, Kim H.K., Hondel C.A.M.J.J. van den, Choi Y.H. & Verpoorte R. (2010), Glucosinolate profiling of Brassica rapa cultivars after infection by Leptosphaeria maculans and Fusarium oxysporum, Biochemical Systematics and Ecology 38(4): 612-620.
- Palama T.L., Fock I., Choi Y.H., Verpoorte R. & Kodja H. (2010), Biological variation of Vanilla planifolia leaf metabolome, Phytochemistry 71(5-6): 567-573.
- Khatib A., Wilson E.G., Supardi M. & Verpoorte R. (2010), Isolation of individual hop iso-α-acids stereoisomers by β-cyclodextrin, Food Chemistry 119: 354-357.
- Simoh S., Linthorst H.J.M., Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2010), Metabolic changes of brassica rapa transformed with bacterial isochorismate synthase gene, Journal of Plant Physiology 167(18): 1525-1532.
- Shikov A.N., Kundracikova M., Palama T.L., Pozharitskaya O.N., Kosman V.M., Makarov V.G., Galambosi B., Kim H.K., Jang Y.P., Choi Y.H. & Verpoorte R. (2010), Phenolic constituents of Gnaphalium uliginosum, Phytochemistry Letters 3: 45-47.
- Liu N.Q., Cao M., Frédérich M., Choi Y.H., Verpoorte R. & Kooy F. van der (2010), Metabolomic investigation of the ethnopharmacological use of Artemisia afra with NMR Spectroscopy and Multivariate Data Analysis, Journal of Ethnopharmacology 128(1): 230-235.
- Lubbe A., Pomahacova B., Choi Y.H. & Verpoorte R. (2010), Analysis of metabolic variation and galanthamine content in Narcissus bulbs by 1H NMR, Phytochemical Analysis 21(1): 66-72.
- Palama T.L., Menard P., Fock I., Choi Y.H., Bourdon E., Govinden-Soulange J., Bahut M., Payet B., Verpoorte R. & Kodja H. (2010), Shoot differentiation from protocorm callus cultures of Vanilla planifolia (Orchidaceae): proteomic and metabolic responses at early stage, Onbekend 10: 82.
- Mirnezhad M., Romero-González R.R., Leiss K.A., Choi H.-K., Verpoorte R. & Klinkhamer P.G.L. (2010), Metabolomic analysis of host plant resistance to thrips in wild and cultivated tomatoes, Phytochemical Analysis 21: 110-117.
- Rijn R.M. van, Rhee I.K. & Verpoorte R. (2010), Isolation of acetylcholine esterase inhibitory alkaloids from Nerium bowdenii, Onbekend 24: 222-225.
- Pec J., Flores-Sanchez I.J., Choi Y.H. & Verpoorte R. (2010), Metabolic analysis of elicited cell suspension cultures of cannabis sativa L. by 1H-NMR spectroscopy, Biotechnology Letters 32(7): 935-941.
- Verpoorte R. (2010), Overview and Introduction. Comprehensive Natural Products II Chemistry and Biology. Oxford: Elsevier.
- Maltese F. & Verpoorte R. (2010), Metabolomics: novel tool for studying complex biological systems. In: Jain S.M. & Brar D.S. (Eds.), In: Molecular techniques in crop improvement.: Springer Science and Business Media.
- Hazekamp A., Fischedick J.T., Diez M.L., Lubbe A., Ruhaak R.L. & Verpoorte R. (2010), Comprehensive Natural Products II Chemistry and Biology. In: Mander L. & Lui H.-W. (Eds.), Chemistry of Cannabis. Oxford: Elsevier. 1033-1084.
- Verpoorte R. (Ed.) (2010), Comprehensive Natural Products II Chemistry and Biology. Oxford: Elsevier.
- Kim H.K. & Verpoorte R. (2010), Sample preparation for plant metabolomics, Phytochemical Analysis 21: 4-13.
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- Kim H.K., Choi Y.H. & Verpoorte R. (2010), NMR-based metabolomic analysis of plants, Nature Physics 5: 536-549.
- Kim H.K., Wilson E., Choi Y.H. & Verpoorte R. (2010), Metabolomics: a tool for anticancer leadfinding from natural products, Planta Medica 76(11): 1094-1102.
- López-Gresa M.P., Maltese F., Bellés J.M., Conejero V., Kim H.K., Choi Y.H. & Verpoorte R. (2010), Metabolic response of tomato leaves upon different plant-pathogen interactions, Phytochemical Analysis 21(1): 89-94.
- Liu N.-Q., Choi Y.H., Verpoorte R. & Kooy F. van der (2010), Comparative quantitative analysis of artemisinin with chromatography and qNMR, Phytochemical Analysis 21(5): 451-456.
- Fischedick J.T., Hazekamp A., Erkelens T., Choi Y.H. & Verpoorte R. (2010), Metabolic fingerprinting of Cannabis sativa L., cannabinoids and terpenoids for chemotaxonomic and drug standardization purposes, Phytochemistry 71(17-18): 2058-2073.
- El-Seedi H.R., El-Barbary M.A., El-Ghorab D.M.H., Bohlin L., Borg-Karlson A.-K., Göransson U. & Verpoorte R. (2010), Recent insights into the biosynthesis and biological activities of natural xanthones, Curr. Med. Chem 17: 854-901.
- Flores-Sanchez I.J., Linthorst H.J.M. & Verpoorte R. (2010), In silicio expression analysis of PKS genes isolated from Cannabis sativa L, Onbekend 33: 703-713.
- Lubbe A., Khatib A., Yuliana N.D., Jinap S. & Verpoorte R. (2010), Cannabinoid CB1 receptor binding and acetylcholinesterase inhibitory activity of Sceletium tortuosum L, Onbekend 17: 349-355.
- Verpoorte R., Frederich M., Delaude C., Angenot L., Dive G., Thepenier P., Jacquier M.-J., Zeches-Hanrot M., Lavaud C. & Nuzillard J.-M. (2010), Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae), Phytochemistry Letters 3: 100-103.
- Kim H.K., Verpoorte R. & Choi Y.H. (Eds.) (2010), Special Issue of Phytochemical Analysis, Metabolomics in Natural Products: Wiley.
- Khatib A., Hoek A.C., Jinap S., Sarker Md.Z.I., Jaswir I. & Verpoorte R. (2010), Application of two Dimensional Thin Layer Chromatography Pattern Comparison for fingerprinting the active compounds in the leaves of Vitex trifolia L possessing anti-tracheospasmolytic activity, J. Liq. Chrom. & Rel. Technol. 33: 214-224.
- Verpoorte R., Choi Y.H. & Kim H.K. (2010), Metabolomics: what is new?, Flavour and Fragrance Journal 25(3): 128-131.
- Leiss K.A., Choi Y.H., Abdel-Farid I.B., Verpoorte R. & Klinkhamer P.G.L. (2009), NMR metabolomics of thrips resistance in Senecio hybrid, Journal of Chemical Ecology 35: 219-229.
- Simoh S., Quintana N., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Metabolic changes in agrobacterium tumefaciens-infected Brassica rapa, Journal of Plant Physiology 166(10): 1005-1014.
- Pomahacova B., Kooy F. van der & Verpoorte R. (2009), Cannabis smoke condensate III: The cannabinoid content of vaporised Cannabis sativa, Inhalation Toxicol. 21: 1108-1112.
- Arany A.M., Jong T.J. de, Kim H.K., Dam N.M. van, Choi Y.H., Mil H.G.J. van, Verpoorte R. & Meijden E. van der (2009), Genotype-environment interactions affect flower and fruit herbivory and plant chemistry of Arabidopsis thaliana in a transplant experiment, Ecological Research 24(5): 1161-1171.
- Maltese F., Erkelens C., Kooy F. van der, Choi Y.H. & Verpoorte R. (2009), Identification of natural enantiomeric flavanone glycosides by NMR spectroscopy, Food Chemistry 116(2): 575-579.
- Khatib A., Yuliana N.D., Jinap S., Sarker Md.Z.I., Jaswir I., Wilson E.G., Chung S.K. & Verpoorte R. (2009), Identification of possible compounds possessing adenosine A1 receptor binding activity in the leaves of Orthosiphon stamineus using TLC and mulitivariate data analysis, J. Liq. Chrom. & Rel. Technol. 32: 2906-2916.
- Yuliana N.D., Khatib A., Link-Struensee A.M.R., IJzerman A.P., Rungkat-Zakari F., Choi Y.H. & Verpoorte R. (2009), Adenosine A1 receptor antagonist activity of methoxy flavonoids from Orthosiphon stamineus, Planta Medica 75(2): 132-136.
- Kooy F. van der, Maltese F., Choi Y.H., Kim H.K. & Verpoorte R. (2009), Quality control of herbal material and phytopharmaceuticals with the use of MS and NMR based metabolic fingerprinting, Planta Med. 75: 763-775.
- El-Seedi H.R., El-Ghorab D.M.H., El-Barbary M.A., Zayed M.F., Goeransson U., Larsson S. & Verpoorte R. (2009), Naturally occurring xanthones; latest investigations: isolation, structure elucidation and chemosystematic significance, Curr. Med. Chem 16: 2581-2626.
- Pomahacova B., Dusek J., Dusková J., Yazaki K., Roytrakul S. & Verpoorte R. (2009), Improved accumulation of ajmalicine and tetrahydroalstonine in Catharanthus cells expressing an ABC transporter, J. Plant Physiol. 166: 1405-1412.
- Palama T.L., Khatib A., Choi Y.H., Fock I., Payet B., Verpoorte R. & Kodja H. (2009), Metabolic changes in different developmental stages of vanilla planifolia pods, Journal of Agricultural and Food Chemistry 57(17): 7651-7658.
- Dayakar V., Badri N., Quintana N., El Kassis E., Kim H.K., Choi Y.H., Suguyama A., Verpoorte R., Martinoia E., Manter D.K. & Vivanco Jorge M. (2009), An ABC transporter mutation alters in root exudation of phytochemicals that provoke an overhaul of natural soil microbiota, Plant Physiology 151(4): 2006-2017.
- Ali K., Maltese F., Choi Y.H. & Verpoorte R. (2009), Metabolic constituents of grapevine and grape-derived products, Phytochemistry Reviews 9: 357–378.
- Flores-Sanchez I.J., Peč J., Fei J., Choi Y.H., Dusek J. & Verpoorte R. (2009), Elicitation studies in cell suspension cultures of Cannabis sativa L, Plant Biotechnology Journal 143(2): 157-168.
- Abdel-Farid I.B., Jahangir M., Hondel C.A.M.J.J. van den, Kim H.K., Choi Y.H. & Verpoorte R. (2009), Fungal infection-induced metabolites in Brassica rapa, Plant Science 176(5): 608-615.
- Mustafa N.R., Kim H.K., Choi Y.H., Erkelens C., Lafeber A.W.M., Spijksma G.K., Heijden R. van der & Verpoorte R. (2009), Biosynthesis of salicylic acid in fungus elicited Catharanthus roseus cells, Phytochemistry 70(4): 532-539.
- Fortes A.M., Batista D., Santos F., Figueiredo A., Serrazina S., Choi Y.H., Miersch O., Lange P., Wasternack C., Verpoorte R. & Pais M.S. (2009), Deciphering morphogenesis for hop improvement. A transcriptomic and metabolomic perspective, Proceedings of the Scientific Commission International Hop Growers' Convention (I.H.G.C.). Scientific Commission International Hop Growers' Convention. Leon 35-40.
- Flores-Sanchez I.J. & Verpoorte R. (2009), Plant polyketide synthases: a fascinating group of enzymes, Plant Physiol. Biochem. 47: 167-174.
- Maltese F., Kooy F. van der & Verpoorte R. (2009), Solvent Derived Artifacts in Natural Products Chemistry, Nat. Prod. Commun. 4: 447-454.
- Fischedick J.T., Glas R., Hazekamp A. & Verpoorte R. (2009), A Qualitative and Quantitative HPTLC Densitometry Method for the Analysis of Cannabinoids in Cannabis sativa L, Phytochemical Analysis 20: 421-426.
- Rashidi H., Akhtar M.T., Kooy F. van der, Verpoorte R. & Duetz W.A. (2009), Hydroxylation and further oxidation of Δ9-tetrahydrocannabinol by alkane degrading bacteria, Appl. Environm. Microbiol. 75: 7135-7141.
- Ali K., Maltese F., Zyprian E., Rex M., Choi Y.H. & Verpoorte R. (2009), NMR metabolic fingerprinting based identification of grapevine metabolites associated with downy mildew resistance, J. Agricult. Food Chem. 57: 9599-9606.
- Leiss K.A., Maltese F., Choi Y.H., Verpoorte R. & Klinkhamer P.G.L. (2009), Identification of chlorogenic acid as a resistance factor for thrips in chrysanthemum, Plant Physiology 150(3): 1567-1575.
- Romero-González R. & Verpoorte R. (2009), Salting-out gradients in centrifugal partition chromatography for the isolation of chlorogenic acids from green coffee beans, J. Chromatogr. A. 1216: 4245-4251.
- Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Health affecting compounds in Brassicaceae, Comprehensive Reviews in Food Science and Food Safety 8(2): 31-43.
- Kooy F. van der, Pomahacova B. & Verpoorte R. (2009), Cannabis smoke condensate II: The effect of tobacco on tetrahydrocannabinol levels, Inhalation Toxicol. 21: 87-90.
- Jahangir M., Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Healthy and unhealthy plants: the effect of stress on the metabolism of Brassicaceae, Environmental and Experimental Botany 67(1): 23-33.
- Mustafa N.R., Kim H.K., Choi Y.H. & Verpoorte R. (2009), Metabolic changes of salicylic acid-elicited catharanthus roseus cell suspension cultures monitored by NMR-based metabolomics, Biotechnology Letters 31: 1967-1974.
- Flores-Sanchez I.J. & Verpoorte R. (2008), Secondary metabolism in Cannabis, Phytochem. Rev 7: 615-639.
- Škrlep K., Bergant M., Winter G.M., Bohanec B., Žel J., Verpoorte R., Iren F. van & Camloh M. (2008), Cryopreservation of cell suspension cultures of Taxus × media and Taxus floridana, Biologia Plantarum 52: 329-333.
- Mustafa N.K., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Single step purification of salicylic acid from Catharanthus roseus cell culture (plant material) by anion exchange for NMR analysis, Journal of Liquid Chromatography and Related Technologies 31: 702-713.
- Taketa A.T.C., Pereda-Miranda R., Choi Y.H., Verpoorte R. & Villarreal M.L. (2008), Metabolomic profiling of the Mexican anxiolytic and sedative plant Galphimia glauca using nuclear magnetic resonance spectroscopy and multivariate data analysis, Planta Medica 74(10): 1295-1301.
- Jahangir M., Abdel-Farid I.B., Choi Y.H. & Verpoorte R. (2008), Metal ions-inducing Metabolites Accumulation in Brassica rapa, Journal of Plant Physiology 165: 1429-1437.
- Verpoorte R. (2008), Repository for ethnopharmacological survey data, 120: 127-128.
- Mosleh Arany A., Jong T.J. de, Kim H.K., Dam N. van, Choi Y.H., Verpoorte R. & Meijden E. van der (2008), Glucosinolates and other metabolites in the leaves of Arabidopsis thaliana from natural populations and their effects on a generalist and a specialist herbivore, Chemoecology: Evolution and mechanisms of the chemical base of ecological interactions 18: 65-71.
- Fortes A., Santos F., Choi Y.H., Figueiredo A.C., Silva M.S., Sousa L., Pessoa F., Acioli B., Sebastiana M., Palme K., Malhó R., Verpoorte R. & Pais M.S. (2008), Organogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses, BMC Genomics 9: 445.
- Chang W.T., Choi Y.H., Heijden R. van der, Kong H., Kim H.K., Verpoorte R., Xu G., Hankemeier T., Greef J. van der & Wang M. (2008), Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa Roots, : .
- Verpoorte R. (2008), Setting standards: diabetes, 115: 161-162.
- Kooy F. van der, Verpoorte R. & Meyer J.J.M. (2008), Metabolomic quality control of claimed anti-malarial Artemisia afra herbal remedy and A. afra and A. annua plant extracts, South African J. Bot. 74: 186-189.
- Kooy F. van der, Maltese F., Choi Y.H., Kim H.K. & Verpoorte R. (2008), Quality control of herbal material and phytopharmaceuticals with the use of MS and NMR based metabolic fingerprinting, Planta Medica : .
- Figueiredo A.C., Fortes M., Ferreira S., Sebastiana M., Choi Y.H., Sousa L., Acioli-Santos B., Pessoa F., Verpoorte R. & Salomé Pais M. (2008), Transcriptional and metabolic profiling of grape (Vitis vinifera L.) leaves unravel possible innate resistance against pathogenic fungi, J. Exp. Bot. 59: 3371-3381.
- Leiss K.A., Choi Y.H., Abdel-Farid I.B., Verpoorte R. & Klinkhamer P.G.L. (2008), NMR metabolomics of thrips resistance in Senecio hybrid, Journal of Chemical Ecology : .
- Škrlep K., Bergant M., Winter G.M., Bohanec B., Žel J., Verpoorte R., Iren F. van & Camloh M. (2008), Cryopreservation of cell suspension cultures of yew: Taxus x media Rehd. and Taxus floridana, Plant Cell, Tissue and Organ Culture : .
- Cardoso-Taketa A., Pereda-Miranda R., Choi Y.H., Verpoorte R. & Villarreal M. (2008), Metabolic profiling of the Mexican anxiolytic and sedative plant Galphimia glauca using nuclear magnetic resonance spectroscopy and multivariate data analysis, Planta Medica 74(10): 1295-1301.
- Zárate R. & Verpoorte R. (2008), Metabolic Engineering of Plant Cellular Metabolism: Methodology, Advances and Future Directions. In: Zhang W. (Ed.), Progress in Bioproducts and Biotechnological Applications: Springer.
- Maltese F. & Verpoorte R. (2008), Metabolomics: novel tool for studying complex biological systems. In: Jain M. (Ed.), Metabolomics: novel tool for studying complex biological systems.
- Verpoorte R. (2008), Medicinal plants: a renewable resource for novel leads and drugs Herbal drugs: Ethnomedicine to modern medicine. In: Ramawat K.G. (Ed.), Ethnomedicine to modern medicine: Springer.
- Verpoorte R. (2008), Medicinal plants: a renewable resource for novel leads and drugs. In: Ramawat K.G. (Ed.), Herbal Drugs: Ethnomedicine to Modern Medicine. Berlin Heidelberg: Springer. 1-5.
- Verpoorte R., Choi Y.H., Mustafa N.K. & Kim H.K. (2008), Metabolomics: back to basics, Phytochemistry Reviews 7: 525-537.
- Sumthong P., Romero-Gonzalez R.R. & Verpoorte R. (2008), Identification of Anti-Wood Rot Compounds in Teak (Tectona grandis L.f.) Sawdust Extract, Wood Chem. Technol. 28: 247-260.
- Verpoorte R., Crommelin D.J.A., Danhof M., Gilissen L.J., Schuitmaker H., Greef J. van der & Witkamp R.F. (2008), Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?", : .
- El-Seedi H.R., El-Ghorab D.M.H., El-Barbary M.A., Larsson S. & Verpoorte R. (2008), Naturally occurring xanthones; latest investigations: isolation, structure elucidation and chemosystematic significance, Curr. Med. Chem : .
- Jahangir M., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Metabolomic response of Brassica rapa submitted to pre-harvest bacterial contamination, Food Chemistry 107(1): 362-368.
- Zuurman L., Roy C., Schoemaker R.C., Hazekamp A., Den Hartigh J., Bender J.C.M.E., Verpoorte R., Pinquier J., Cohen A.F. & Gerven J.M.A. van (2008), Effect of intrapulmonary tetrahydrocannabinol administration in humans, Journal of Psychopharmacology 22: 707-716.
- Ridder S. de, Kooy F. van der & Verpoorte R. (2008), Artemisia annua as a self-reliant treatment for malaria in developing countries, 120: 302-314.
- Flores-Sanchez I.J. & Verpoorte R. (2008), Activities and Biosynthesis of Cannabinoids and Flavonoids in Cannabis sativa L. Plants, Plant and Cell Physiology 49(12): 1767-1782.
- Jahangir M., Bayoumi I., Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2008), Stress induced metabolic responses in food plants of Brassicaceae, Mol. Biosystem. : .
- Karlsson P., Pettersson J., Choi Y.H., Verpoorte R., Bohlin L. & Rafter J.J. (2008), NMR metabolomic analysis of fecal water from subjects on a vegetarian diet, Biological and Pharmaceutical Bulletin 31(6): 1192-1198.
- Flores-Sanchez I.J. & Verpoorte R. (2008), Plant polyketide synthases: a fascinating group of enzymes, Plant Physiology and Biochemistry : .
- Angelova N.S., Kong H.W., Heijden R. van der, Yang S.Y., Choi Y.H., Kim H.K., Wang M., Hankemeier T., Greef J. van der, Xu X. & Verpoorte R. (2008), Recent methodology in the phytochemical analysis of ginseng, Phytochemical Analysis 19: 2-16.
- Fraccaroli M., Nicoletti S., Maltese F., Choi Y.H., Guzzo F., Levi M. & Verpoorte R. (2008), Preanalytical method for metabolic profiling of plant cell cultures of Passiflora garckei, Biotechnology Letters 30: 2031-2035.
- Simoh S., Linthorst H.J.M. & Verpoorte R. (2008), Host-bacterium interactions in Agrobacterium tumefaciens-mediated plant transformation: Mechanism of action and Agrobacterium/plant factors involved, Plant Biology 8: 1-20.
- Dao T.H.H., Puig R.C., Kim H.K., Erkelens C., Lefeber A.W.M., Linthorst H.J.M., Choi Y.H. & Verpoorte R. (2008), Effect of benzothiadiazole on the metabolome of Arabidopsis thaliana, Plant Physiology and Biochemistry 47(2): 146-152.
- Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2007), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, Journal of Biotechnology 128: 72-79.
- Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2007), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, Journal of Biotechnology 128: 72-79.
- Roytrakul S. & Verpoorte R. (2007), Role of vacuolar transporter proteins in plant secondary metabolism: Catharanthus roseus cell culture, 6: 383-396.
- Sanchez-Sampredo A., Kim H.K., Choi Y.H., Verpoorte R. & Corchete P. (2007), Metabolomic alterations in elicitor treated Silybum marianum suspension cultures monitored by nuclear magnetic resonance spectroscopy, Journal of Biotechnology 130(2): 133-142.
- Hazekamp A., Bastola K., Rashidi H., Bender J. & Verpoorte R. (2007), Cannabis tea revisited: A systematic evaluation of the cannabinoid composition of cannabis tea, 113: 85-90.
- Korthout H.A. & Verpoorte R. (2007), Vanilla. In: , Flavours and Fragrances. Chemistry, Bioprocessing and Sustainability. Berlin: Springer-Verlag. 203-217.
- Verpoorte R. (2007), Introduction. In: Verpoorte R., Alfermann A.W. & Johnson T.S. (Eds.), Applications of plant metabolic engineering. Dordrecht: Springer. XI-XXI.
- Khatib A., Wilson E.G., Kim H.K., Supardi M., Choi Y.H. & Verpoorte R. (2007), NMR assignment of iso--acids from isomerised extracts of Humulus lupulus L. cones, Phytochemical Analysis 18: 371-377.
- El-Sayed M. & Verpoorte R. (2007), Catharanthus terpenoid indole alkaloids: biosynthesis and regulation, 6: 277-305.
- Bastola K., Hazekamp A. & Verpoorte R. (2007), Synthesis and spectroscopic characterization of cannabinolic acid, Planta Medica 73: 273-275.
- El-Seedi H.R., El-Hamid N.S.A., Goransson U. & Verpoorte R. (2007), Cyclopeptide alkaloids, 6: 143-165.
- Mustafa N.R. & Verpoorte R. (2007), Phenolic compounds in Catharanthus roseus, 6: 243-258.
- Verpoorte R., Choi Y.H. & Kim H.K. (2007), NMR-based metabolomics at work in phytochemistry, 6: 3-14.
- Zarate R. & Verpoorte R. (2007), Strategies for the Genetic Modification of the Medicinal Plant Catharanthus roseus (L.) G. Don, 6: 475-491.
- Zhao J. & Verpoorte R. (2007), Manipulating indole alkaloid production by Catharanthus roseus cell cultures in bioreactors: From biochemical processing to metabolic engineering, 6: 435-457.
- Abdel-Farid I.B., Kim H.K., Choi Y.H. & Verpoorte R. (2007), Metabolic characterization of Brasica rapa leaves by NMR-spectroscopy, Journal of Agricultural and Food Chemistry 55(19): 7936-7943.
- Verberne M.C., Sansuk K., Bol J.F., Linthorst H.J.M. & Verpoorte R. (2006), Vitamin K1 accumulation in tobacco plants overexpressing bacterial genes involved in the biosynthesis of salicylic acid, 29: 293-302.
- Widarto H.T., Meijden E. van der, Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2006), Metabolomic differentiation of Brassica rapa following herbivory by different insect instars using two dimensional nuclear magnetic resonance spectroscopy, Journal of Chemical Ecology 32(11): 2417-2428.
- Sumthong P., Damveld R.A., Choi Y.H., Arentshorst M., Ram A.F.J., Hondel C.A.M.J.J. van den & Verpoorte R. (2006), Activity of quinones from teak (Tectona grandis) on fungal cell wall stress, Planta Medica 72(10): 943-944.
- Trevisan M.T.S., Barbosa Bezerra M.Z., Pinheiro Santiago G.M., Mendes Feitosa C., Verpoorte R. & Braz Filho R. (2006), Atividades larvacida e anticolinesterasica de plantas do genero Kalanchoe Quim, NOVA 29: 415-418.
- Hazekamp A., Ruhaak R., Zuurman L., Gerven J.M.A. van & Verpoorte R. (2006), Evaluation of a vaporizing device (Volcano) for the pulmonary administration of tetrahydrocannabinol, JOURNAL OF PHARMACEUTICAL SCIENCES 95: 1308-1317.
- Choi Y.H., Kim H.K., Verpoorte R., Linthorst H.J.M., Hollander J., Lefeber A.W.M., Erkelens C. & Nuzillard J.-M. (2006), NMR metabolomics to revisit the tobacco mosaic virus infection in Nicotiana tabacum leaves, 69: 742-742.
- Thongphasuk P., Suttisri R., Bavovada R. & Verpoorte R. (2006), Two new pimarane diterpenoids from Strychnos vanprukii Craib, Journal of Asian Natural Products Research 20: 966-968.
- Choi Y.H., Kim H.K. & Verpoorte R. (2006), Metabolomics. In: Kayser O. & Quax W. (Eds.), Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Weinheim: Wiley-VCH. 9-28.
- Verpoorte R. & Hoopen H.J.G. ten (2006), Plant Cell Biotechnology. In: Ratledge C. & Kristiansen B. (Eds.), Basic Biotechnology. Cambridge: Cambridge University Press. 549-577.
- Kim H.K., Choi Y.H. & Verpoorte R. (2006), Metabolomic analysis of Catharanthus roseus using NMR and principal component analysis. Biotechnology. In: Saito K., Dixon R. & Willmitzer L. (Eds.), Plant Metabolomics. Biotechnology in Agriculture and Forestry. Biotechnology in Agriculture and Forestry no. 57. Heidelberg: Springer. 261-276.
- El-Seedi H.R., El-Hamid N.S.A., Goransson U. & Verpoorte R. (2006), Cyclopeptide alkaloids, : .
- Abdel-Farid I.B., Choi Y.H., Kim H.K., Hondel C.A.M.J.J. van den, Meijden E. van der & Verpoorte R. (2006), The role of secondary metabolites in Arabidopsis and Brassica in the interaction with fungi, Current Topics in Microbiology and Immunology 7: 47-73.
- Verpoorte R. (2006), Application of Two Dimensional Nuclear Magnetic Resonance Spectroscopy to Quality Control of Ginseng Commercial Products, Planta Medica 72: 364-369.
- Yang S.Y., Kim H.K., Lefeber A.W.M., Erkelens C., Angelova N.S., Choi Y.H. & Verpoorte R. (2006), Application of two-dimensional nuclear magnetic resonance spectroscopy to quality control of ginseng commercial products, Planta Medica 72(4): 364-369.
- Hazekamp A. & Verpoorte R. (2006), Structure elucidation of the tretrahydrocannabinol complex with randomly methylated Beta-cyclodextrin, European Journal of Pharmaceutical Sciences 29: 340-347.
- Liang Y.-S., Choi Y.H., Kim H.K., Linthorst H.J.M. & Verpoorte R. (2006), Metabolomic analysis of methyl jasmonate treated Brassica rapa leaves by 2-dimensional NMR spectroscopy, Phytochemistry 67(22): 2503-2511.
- Khatib A., Kim H.K., Wilson E.G., Choi Y.H. & Verpoorte R. (2006), High performance liquid chromatographic method for Iso‐α‐Acids, Journal of Liquid Chromatography and Related Technologies 29(2): 293-302.
- Khatib A., Wilson E.G., Kim H.K., Lefeber A.W.M., Erkelens C., Choi Y.H. & Verpoorte R. (2006), Application of two dimensional J-resolved nuclear magnetic resonance spectrum to differentiation of beer, Analytica Chimica Acta 559(2): 264-270.
- Liang Y.-S., Lefeber A.W.M., Erkelens C., Kim H.K., Choi Y.H. & Verpoorte R. (2006), Identification of phenylpropanoids in Brassica rapa leaves treated with methyl jasmonate using two-dimensional nuclear magnetic resonance spectroscopy, Journal of Chromatography A 1112: 148-155.
- Hendrawati O., Yao Q., Choi Y.H., Kim H.K., Linthorst H.J.M., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2006), Metabolic differentiation of Arabidopsis treated with methyl jasmonate using nuclear magnetic resonance spectroscopy, Plant Science 170(6): 1118-1124.
- Dignum M.J.W. & Verpoorte R. (2005), Enzymes in curing vanilla. Frenkel D. (Ed.), Vanilla. .
- Verpoorte R., Kim H.K. & Choi Y.H. (2005), New perspectives of medicinal plants in a globalized world. Mukherjee P.K. (Ed.), Proceedings International Conference on Botanicals. . Kolkata, India: Allied Book Agency. 11-18.
- El-Sayed M. & Verpoorte R. (2005), Methyljasmonate accelerates catabolism of monoterpenoid indole alkaloids in Catharanthus roseus during leaf processing, Fitoterapia 76: 83-90.
- Verpoorte R. (2005), Ethnopharmacology and systems biology: a perfect holistic match, 100: 1-2.
- Jacobs D.I., Gaspari M., Greef J. van der, Heijden R. van der & Verpoorte R. (2005), Proteome analysis of Catharanthus roseus cultured cells for the identification of proteins involved in alkaloid biosynthesis and finding of novel sequences, Planta 221: 690-704.
- Choi Y.H., Sertic S., Kim H.K., Wilson E.G., Michopoulosa F., Lefeber A.W.M., Erkelens C., Kricun S.D.P. & Verpoorte R. (2005), Classification of Ilex species based on metabolomic fingerprinting using nuclear magnetic resonance and multivariate data analysis, Journal of Agricultural and Food Chemistry 53(4): 1237-1245.
- Canto-Canche B.B., Meijer A.H., Collu G., Verpoorte R. & Loyola-Vargas V.M. (2005), Characterization of a polyclonal antiserum against the monoterpene monooxygenase, geraniol 10-hydroxylase from Catharanthus roseus, Journal of Plant Physiology 162: 393-402.
- Kirk H.E., Choi Y.H., Kim H.K., Verpoorte R. & Meijden E. van der (2005), Comparing metabolomes: the chemical consequences of hybridization in plants, New Phytologist 167(2): 613-622.
- Hazekamp A., Peltenburg A., Verpoorte R. & Giroud C. (2005), Chromatographic and spectroscopic data of cannabinoids from Cannabis sativa L, Journal of Liquid Chromatography and Related Technologies 28: 2361-2382.
- Iren F. van, Winter W. de, Roytrakul S., Choi Y.H., Verpoorte R. & Suhartono L. (2005), Metabolic comparison of cryopreserved and normal cells from Tabernaemontana divaricata suspension cultures, Plant Cell, Tissue and Organ Culture 83: 59-66.
- Rauter A.P., Martins A., Borges C., Ferreira J., Justino J., Bronze M.R., Coelho A.V., Choi Y.H. & Verpoorte R. (2005), Liquid Chromatography-diode array detection-electronspray ionisation mass spectrometry/nuclear magentic resonance analyses of the anti-hyperglemic flavonoid extract of Genista tenera: structure elucidation of a flavonoid-C-glycoside, Journal of Chromatography A 1089(1-2): 59-64.
- Hazekamp A., Serier P., Verpoorte R., Bender J. & Bakel N. van (2005), Cannabis uit de apotheek is beter, Pharmaceutisch Weekblad 140: 402-404.
- Jacobs D.I., Gaspari M., Greef J. van der, Heijden R. van der & Verpoorte R. (2005), Proteome analysis of the medicinal plant Catharanthus roseus, Planta 221: 690-704.
- Kim H.K., Choi Y.H., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2005), Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principle component analysis, Chemical and pharmaceutical bulletin 53(1): 105-109.
- Zhao J., Davis L.C., Tang X. & Verpoorte R. (2005), Elicitor Signal Transduction Leading to Production of Plant Secondary Metabolites, Biotechnology Advances 23: 283-333.
- Wang M., Lamers R.J., Korthout H.A., Nesselrooij J.H. van, Witkamp R.F., Heijden R. van der, Voshol P.J., Havekes L.M., Verpoorte R. & Greef J. van der (2005), Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology, Phytotherapy Research 19(3): 173-182.
- Wang M., Lamers R.J., Korthout H.A., Nesselrooij J.H. van, Witkamp R.F., Heijden R. van der, Voshol P.J., Havekes L.M., Verpoorte R. & Greef J. van der (2005), Metabolomics in the context of systems biology: bridging traditional Chinese medicine and molecular pharmacology, Phytotherapy Research 19(3): 173-182.
- Rhee I.K., Appels N., Hofte B., Karabatak B., Erkelens C., Stark L.M., Flippin L.A. & Verpoorte R. (2004), Isolation of the Acetylcholinesterase inhibitor ungeremine from Nerine bowdenii isolated by preparative HPLC coupled online to a flow assay system, Biological Pharmaceutical Bulletin 27: 1804-1809.
- Choi Y.H., Choi H.-K., Peltenburg-Looman A.M.G., Lefeber A.W.M. & Verpoorte R. (2004), Quantitative analysis of ginkgolic acids from Ginkgo leaves and products using 1HNMR, Phytochemical Analysis 15: 325-330.
- Heijden R. van der, Jacobs D.I., Snoeijer W., Hallard D. & Verpoorte R. (2004), Catharanthus roseus alkaloids: Pharmacognosy and biotechnology, Current Medicinal Chemistry 11: 1241-1253.
- Dignum M., Heijden R. van der, Kerler J., Winkel C. & Verpoorte R. (2004), Identification of glucosides in green beans of Vanilla planifolia Andrews and kinetics of vanilla beta-glucosidase, Food Chemistry 85: 199-205.
- Choi H.-K., Choi Y.H., Verberne M., Lefeber A.W.M., Erkelens C. & Verpoorte R. (2004), Metabolic fingerprinting of wild type and transgenic tobacco plants by 1H NMR and multivariate analysis technique, Phytochemistry 65(7): 857-864.
- Choi Y.H., Kim H.K., Wilson E., Erkelens C., Trijzelaar B. & Verpoorte R. (2004), Quantitative analysis of retinol and retinol palmitate in vitamin tablets using 1H-nuclear magnetic resonance spectroscopy, Analytica Chima Acta 512: 141-147.
- Choi Y.H., Hazekamp A., Peltenburg-Looman A.M.G., Frederich M., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2004), NMR Assignment of major cannabinoids and cannbiflavonoids isolated from Cannabis sativa flowers, Phytochemical Analysis 15: 345-354.
- Choi Y.H., Kim H.K., Hazekamp A., Erkelens C., Lefeber A.W.M. & Verpoorte R. (2004), Metabolomic differentiation of Cannabis sativa cultivars using 1H-NMR and principal component analysis, Journal of Natural Products 67(6): 953-957.
- El-Sayed M., Choi Y.H., Frédérich M., Roytrakul S. & Verpoorte R. (2004), Alkaloid accumulation in Catharanthus roseus cell suspension cultures fed with stemmadenine, Biotechnology Letters 26(10): 793-798.
- Kim H.K., Choi Y.H., Luijendijk T.J.C., Rocha R.A.V. & Verpoorte R. (2004), Comparison of extraction methods for secologanin and the quantitative analysis of secologanin from symphoricarpos albus using 1H‐NMR, Phytochemical Analysis 15(4): 257-261.
- Frederich M., Cristino A., Choi Y.H., Verpoorte R., Tits M., Angenot L. & Zeches-Hanrot M. (2004), Chrysopentamine, an antiplasmodial anhydronium base from Strychnos usambarensis leaves, Planta Medica 70(1): 72-76.
- Hazekamp A., Simons R., Peltenburg-Looman A.M.G., Sengers M., Zweden R. van & Verpoorte R. (2004), Preparative isolation of cannabinoids from Cannabis sativa by centrifugal partitioning chromatography, J. Liq. Chrom. & Rel. Technol. 27: 2421-2440.
- Choi Y.H., Casas Tapias E., Kim H.K., Lefeber A.W.M., Erkelens C., Verhoeven J.TH.J., Brzin J., Zel J. & Verpoorte R. (2004), Metabolic discrimination of Catharanthus roseus leaves infected by phytoplasma using 1HNMR spectroscopy and multivariate data analysis, Plant Physiology 135(4): 2398-2410.
- Frederich M., Choi Y.H., Angenot L., Harnischfeger G., Lefeber A.W.M., Erkelens C. & Verpoorte R. (2004), Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by 1 H nuclear magnetic resonance spectrometry and multivariate analysis techniques, Phytochemistry 65(13): 1993-2001.
- Raharjo T.J. & Verpoorte R. (2004), Methods for cannabinoids analysis in biological materials, Phytochemical Analysis 15: 79-94.
- Raharjo T.J., Chang W.T., Choi Y.H., Peltenburg-Looman A.M.G. & Verpoorte R. (2004), Olivetol as product of a polyketide synthase (PKS) in Cannabis sativa, Plant Science 166: 381-385.
- Raharjo T.J., Chang W.T., Verberne M.C., Peltenburg-Looman A.M.G. & Verpoorte R. (2004), Cloning and overexpression of a cDNA encoding a polyketide sythase (PKS) from Cannabis sativa L, Plant Physiology and Biochemistry 42: 291-297.
- Chatzimichalakis P.F., Samanidou V.F., Verpoorte R. & Papadoyannis I.N. (2004), Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceutical formulations and biological fluids after solid phase extraction, J. Sep. Sci 27: 1181-1188.
- Whitmer S., Canel C., Heijden R. van der & Verpoorte R. (2003), Long-term instability of alkaloid production by stably transformed cell lines of Catharanthus roseus, Plant Cell, Tissue and Organ Culture 74: 73-80.
- Rhee I.K., Appels N., Luijendijk T., Irth H. & Verpoorte R. (2003), Determining Acetylcholinesterase Inhibitory activity in Plant Extracts using a Fluorometric Flow Assay, Phytochemical Analysis 14: 145-149.
- Trevisan M.T.S., Viana Macedo F., Meent M. van de, Rhee I.K. & Verpoorte R. (2003), Selecão de plantas com atividade anticolinasterase para tratamento da doenca de Alzheimer, Quimica Nova 26: 301-304.
- Rhee I.K., Rijn R.M. van & Verpoorte R. (2003), Qualitative determination of false-positive effects in the acetylcholinesterase assays using thin layer chromatography, Phytochemical Analysis 14: 127-131.
- Thongphasuk P., Suttisri R., Bavovada R. & Verpoorte R. (2003), Alkaloids and a pimarane diterpenoid from Strychnos vanprukii, Phytochemistry 64: 897-901.
- Twyman R.M., Verpoorte R., Memlink J. & Christou P. (2003), Genetic modification of secondary metablism: Alkaloids. In: Murphy Thomas B. & Marray B. (Eds.), Encyclopedia of Applied Plant Sciences. New York: Academic Press. 493-500.
- Mustafa N.K., Rhee I.K. & Verpoorte R. (2003), Rapid method for determination of galanthaminie in Amaryllidaceae plants using high performance liquid chromatography, J. Liq. Chrom. & Rel. Technol. 26: 3217-3224.
- Trevisan M.T.S., Scheffer J.J.C. & Verpoorte R. (2003), Peroxidase activity in hop plants after infestation by red spider mites, Crop protection 22: 423-424.
- Han Y.-S., Hofte B., Heijden R. van der & Verpoorte R. (2003), Analysis of Anthraquinones in Cell Cultures of Cinchona ‘Robusta” by HPLC with Photodiode Array and Mass Spectrometry Detection, Phytochemical Analysis 14: 298-305.
- El Hassan A., El-Sayed M., Hamed A.I., Rhee I.K., Ahmed A.A., Zeller K.P. & Verpoorte R. (2003), Bioactive constituents of Leptadenia arborea, Fitoterapia 74: 184-187.
- Han Y.-S., Hofte B., Heijden R. van der & Verpoorte R. (2003), Analysis of anthraquinones in cell cultures of Cinchona "robusta" by HPLC with diode array and mass spectrometry detection, Phytochemical Analysis 14: 298-305.
- Rhee I.K., Appels N., Luijendijk T., Irth H. & Verpoorte R. (2003), Determining acetylcholinesterase inhibitory activity in plant extracts using a fluorimetric flow assay, Phytochemical Analysis 14: 145-149.
- Unver N., Kaya G.I., Werner C., Verpoorte R. & Gözler B. (2003), Galanthindole: a new indole alkaloid from Galanthus plicatus ssp. byzantinus, Planta Medica 69: 869-871.
- Han Y.-S., Roytrakul S., Verberne M.C., Heijden R. van der, Linthorst H.J.M. & Verpoorte R. (2003), Cloning of a cDNA encoding 1-deoxy-D-xylulose 5-phosphate synthase from Morinda citrifolia and analysis of its expression in relation to anthraquinone accumulation, Plant Science 164: 911-917.
- Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (2003), Anti-inflammatory, antipyretic and antinociceptive activities of Tabernaemontana pandacaqui, 84: 31-35.
- Choi Y.H., Choi H.-K., Hazekamp A., Bermejo P., Schilder Y.D.C., Erkelens C. & Verpoorte R. (2003), Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using H-1-NMR, Chemical and pharmaceutical bulletin 51: 158-161.
- Han Y.-S., Sabbioni C., Heijden R. van der & Verpoorte R. (2003), High-performance liquid chromatography assay for 1-deoxy-D-xylulose 5-phosphate synthase activity using fluorescence detection, Journal of Chromatography A 986: 291-296.
- Halim V.A., Verberne M.C. & Verpoorte R. (2003), Differential metabolic profiling by HPLC-PDA-MS of wild type and transgenic tobacco plants constitutively producing salicylic acid, J. Liq. Chrom. & Rel. Technol. 26: 369-383.
- Frederich M., Choi Y.H. & Verpoorte R. (2003), Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR, Planta Medica 69: 1169-1171.
- Budi Muljuno R.A., Scheffer J.J.C. & Verpoorte R. (2003), Effect of feeding salicyclic acid on 2,3-dihydroxybenzoic acid formation in cultured cells of Catharanthus roseus, Pharm. Biol. 41: 284-291.
- Kim H.K., Choi Y.H., Wen-Te Chang R. & Verpoorte R. (2003), Quantitative analysis of ephedrine analogues from Ephedra species using H-1-NMR, Chemical and pharmaceutical bulletin 51: 1382-1385.
- Kraemer K.H., Stival A.L., Ferreira A.G., Schenkel E.P. & Verpoorte R. (2002), Ilex paraguariensis cell suspension culture characterization and response against ethanol, Plant Cell, Tissue and Organ Culture 68: 57-63.
- Verpoorte R. & Memelink J. (2002), Engineering secondary metabolite production in plants, Current Opinion in Biotechnology 13: 181-187.
- Luckiewicz M., Zarate R., Dembinska-Migas W., Migas P. & Verpoorte R. (2002), Production of pulchelin E in hairy roots, callus and suspension cultures of Rudbeckia hirta L, Plant Science 163: 91-100.
- Araujo P.S., Maraschin M., Passos Maraschin R. dos, Caro M.G.S. & Verpoorte R. (2002), Kinetics of the carbohydrate metabolism in Mandevilla velutina cell cultures by 1HNMR, Applied Magnetic Resonance 1: 102-109.
- Ingkaninan K., Irth H. & Verpoorte R. (2002), Screening of Amaryllidaceae for biological activities: Acetylcholineesterase inhibitors in Narcissus. In: Hanks G.R. (Ed.), The genus Narcissus. London: Harwood Pulishers. 369-379.
- Whitmer S., Heijden R. van der & Verpoorte R. (2002), Genetic engineering of the plant cell factory for secondary metabolite production. Indole Alkaloid production in Catharanthus roseus as a model. In: Oksman-Caldentey K.M. & Barz W.H. (Eds.), Plant biotechnology and transgenic plants. New York: Marcel Dekker. 373-404.
- Verpoorte R., Ingkaninan K., Memelink J. & Heijden R. van der (2002), New perspectives for plant secondary metabolite production. Rauter A.P., Palma F.B., Justino J., Araujo M.E.A. & Santos S.P. dos (Eds.), Proceedings Phytochemical Society of Europe. . Dordrecht: Kluwer Academic Publishers. 345-366.
- Nugroho L.H. & Verpoorte R. (2002), Secondary metabolism in tobacco, Plant Cell, Tissue and Organ Culture 68: 105-125.
- Dignum M.J.W. & Verpoorte R. (2002), Glucosylation of exogenous vanillin by plant cell cultures, Plant Cell, Tissue and Organ Culture 69: 177-182.
- Whitmer S., Heijden R. van der & Verpoorte R. (2002), Effect of precursor feeding on alkaloid accumulation by a strictosidine synthase over-expessing transgenic cell line S1 of Catharanthus roseus, Plant Cell, Tissue and Organ Culture 69: 85-93.
- Maraschin M., Sugui J.A., Wood K.V., Bonham C., Buchi D.F., Cantao M.P., Carobrez S.G., Araujo P.S., Peixoto M.L., Verpoorte R. & Fontana J.D. (2002), Somaclonal variation: a morphogenetic and biochemical approach in Mandevilla velutina cultured cells, Braz. J. Med. Biol. Res. 35: 633-643.
- Alam G., Wahyuono S., Ganjar I.G., Hakim L., Timmerman H. & Verpoorte R. (2002), Tracheospasmolytic activity of viteosin-A and vitexicarpin isolated from Vitex trifolia, Planta Medica 68: 1047-1049.
- Pelser P.B., Kruijer H.J.D. & Verpoorte R. (2002), What is the function of oil-containing rudimentery branches in the moss Canalohypopterygium tamariscinum (Hedw.) Kruijer (Hypopterygiaceae), New Zealand J. Bot. 40: 149-153.
- Dignum M., Kerler J. & Verpoorte R. (2002), Vanilla curing under laboratory conditions, Food Chemistry 79: 165-171.
- Han Y.S., Heijden R. van der, Lefeber A.W.M., Erkelens C. & Verpoorte R. (2002), Biosynthesis of antrhraquinones in Cell Cultures of Cinchona Robusta proceeds via the Methylerythritol 4-Phosphate Pathway, Phytochemistry 59: 45-55.
- Verpoorte R., Contin A. & Memelink J. (2002), Biotechnology for the production of plant secondary metabolites, 1: 13-25.
- Han Y.-S., Heijden R. van der & Verpoorte R. (2002), Improved anthraquinone accumulation in cell cultures of Cinchona "robusta" by feeding of biosynthetic precursors and inhibitors, Biotechnology Letters 24: 705-710.
- Nugroho L.H., Peltenburg-Looman A.M.G., Vos H. de, Verberne M.C. & Verpoorte R. (2002), Nicotine and related alkaloids accumulation in constitutive salicylic acid producing tobacco plants, Plant Science 162: 575-581.
- Whitmer S., Heijden R. van der & Verpoorte R. (2002), Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase overexpressing transgenic cell line T22 of Catharanthus roseus, Journal of Biotechnology 96: 193-203.
- Nugroho L.H., Peltenburg-Looman A.M.G., Verberne M.C. & Verpoorte R. (2002), Is accumulation of sesquiterpenoid phytoalexins induced in tobacco plants constitutively producing salicylic acid?, Plant Science 162: 989-993.
- Nugroho L.H., Verberne M.C. & Verpoorte R. (2002), Activities of enzymes involved in the phenylpropanoid pathway in constitutive salicylic acid producing transgenic tobacco plants, Plant Physiology and Biochemistry 40: 755-760.
- Heijden R. van der & Verpoorte R. (2002), Effects of alkaloid precursor feeding on a Camptotheca acuminata cell line, Plant Physiology and Biochemistry 40: 749-753.
- Hoopen H.J.G. ten, Vinke J.L., Moreno P.R.H., Verpoorte R. & Heijnen J.J. (2002), Influence of temperature on growth and ajmalicine production by Catharanthus roseus suspension cultures, Enzyme and Microbial Technology 30: 56-65.
- Budi Muljono R.A., Scheffer J.J.C., Talou J.R. & Verpoorte R. (2002), Biosynthesis of 2,3-dihydroxybenzoic acid in transgenic Catharanthus roseus cell cultures overpressing isochorismate synthase, Heterocycles 56: 341-352.
- El-Sayed M. & Verpoorte R. (2002), Effect of phytohormones on growth and alkaloid accumulation by a Catharanthus roseus cell suspension culture fed with precursors of the alkaloid biosynthesis, Plant Cell, Tissue and Organ Culture 68: 265-270.
- Lucumi E., Vera A., Hallard D., Heijden R. van der & Verpoorte R. (2002), Alkaloid Formation in Cell Suspension Cultures of Tabernaemontana elegans after Feeding of Tryptamine and Loganin or Secologanin, Plant Cell, Tissue and Organ Culture 68: 293-299.
- Budi Muljono R.A., Scheffer J.J.C. & Verpoorte R. (2002), Isochorismate is an intermediate in 2,3-dihydroxybenzoic acid biosynthesis in Cathranthus roseus cell cultures, Plant Physiology and Biochemistry 40: 231-234.
- Verberne M.C., Brouwer N., Delbianco F., Linthorst H.J.M., Bol J.F. & Verpoorte R. (2002), Method for the extraction of the volatile compound salicyclic acid from tobacco leaf material, Phytochemical Analysis 13: 45-50.
- Zárate R., Memelink J., Heijden R. van der & Verpoorte R. (1999), Genetic transformation via particle bombardment of Catharanthus roseus plants through adventitious organogenesis of buds, Biotechnology Letters 21: 997-1002.
- Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1999), Novel approaches to improve plant secondary metabolite production. In: Fu T.-J., Singh G. & Curtis W.R. (Eds.), Plant Cell and Tissue Culture for the Production of Food Ingredients. New York: Kluwer Academic/Plenum Publishers. 85-100.
- Verpoorte R., Heijden R. van der, Memelink J. & Hoopen G. ten (1999), Metabolic engeering: A strategy to improve plant secondary metabolite production. In: Hostettmann K., Gupta M.P. & Marston A. (Eds.), Chemistry, biological and pharmacological properties of medicinal plants from the Americas. Amsterdam: Harwood Academic Publishers. 207-219.
- Geerlings A., Redondo F.J., Memelink J., Contin A., Heijden R. van der & Verpoorte R. (1999), Screening method for cDNAs encoding putative enzymes converting loganin into secologanin by a transgenic yeast culture, Biotechnology Letters 13: 605-608.
- Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1999), Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals, Biotechnology Letters 21: 467-479.
- Ouwerkerk P.B.F., Hallard D., Verpoorte R. & Memelink J. (1999), Identification of UV-B light-responsive regions in the promoter of the tryptophan decarboxylase gene from Catharanthus roseus, 41: 491-503.
- Verpoorte R. (1998), Metabolic engineering as a strategy to improve the production of secondary metabolite production in plants or plant cell cultures, Acta Horticulture : .
- Verpoorte R., Heijden R. van der & Memelink J. (1998), Plant biotechnology and the production of alkaloids: prospects of metabolic engineering. In: Cordell G.A. (Ed.), The Alkaloids. San Diego, USA: Academic Press. 453-508.
- Verpoorte R. (1998), Chemodiversity and the biological role of secondary metabolites, some thoughts for selecting plant material or drug develpment. In: Bohlin L. & Bruhn J.G. (Eds.), Bioassay Methods in Natural Product Research and Drug Development. Dordrecht, NL: Kluwer Academic Publishers. 11-24.
- Heijden R. van der & Verpoorte R. (1998), Metabolic engineering of plant secondary metabolism. In: , In vitro plant cell engineering: Le Biopole Vegetal/IAPTC. 19-23.
- Verpoorte R. (1998), Antimicrobial activity of alkaloids. In: Roberts M.F. & Wink M. (Eds.), Alkaloids: biochemistry, ecology and medicinal applications.. New York: Plenum Publishing Corporation. 397-433.
- Heijden R. van der, Schulte A.E., Ramos-Valdivia A.C. & Verpoorte R. (1998), Characterization of some isoprenoid-biosynthesic enzymes from plant cell cultures. In: Kieslich K., Bont J.A.M. de, Beek C.P. van der & Tweel W.J.J. van den (Eds.), Studies in Organic Chemistry, Vol 53, New Frontiers in screening for microbial biocatalysts. Amsterdam, NL: Elsevier. 177-185.
- Romeo J.T., Downum K.R. & Verpoorte R. (1998), Phytochemical signals and plant-microbe interactions. In: Romeo J.T., Downum K.R. & Verpoorte R. (Eds.), Recent Advances in Phytochemistry: Plenum Press.
- Verpoorte R. (1998), Metabolic engineering, improving production of plant secondary metabolism. Universidad Tecnologica de Pereira. Pereira, Columbia. [lecture].
- Heijden R. van der, Schulte A.E., Contin A. & Verpoorte R. (1998), Alternatieve biosynthese terpenoiden ontdekt. Chemisch Weekblad: 90-92.
- Höft M., Verpoorte R. & Beck E. (1998), Leaf alkaloid contents of Tabernaemontana pachysiphon as influenced by endogenous and environmental factors in the natural habitat, Planta Medica 64: 148-152.
- Ramos-Valdivia A.C., Heijden R. van der & Verpoorte R. (1998), Isopentenyl diphosphate isomerase and prenyltransferase activities in rubiaceous and apocynaceous cultures, Phytochemistry 48: 961-969.
- Kraemer K.H., Schenkel E.P. & Verpoorte R. (1998), Biotransformation of alcohol in Ilex paraguariensis cell suspension cultures: triterpenes and carbohydrates, Plant Cell Reports : .
- Theodoridis G., Jong C.F. de, Laskaris G. & Verpoorte R. (1998), Application of SPE for the HPLC analysis of taxanes from Taxus cell cultures, Chromatographia 47: 25-34.
- Luijendijk T.J.C., Stevens L.H. & Verpoorte R. (1998), Purification and characterisation of strictosidine ß-D-glucosidase from Catharanthus roseus cell suspension cultures, Plant Physiology and Biochemistry 36: 419-425.
- Verpoorte R. (1998), Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development, Drug Discovery Today 3: 232-238.
- Gournelis D.C., Laskaris G. & Verpoorte R. (1998), Cyclopeptide alkaloids. In: , Progress in the Chemistry of Organic Natural Products.. Wien, Austria: Springer-Verlag. 1-179.
- Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (1998), Cardiovascular activity of the crude alkaloidal fraction from Tabernaemontana pandacaqui in the rat, 59: 131-137.
- Verberne M.C., Budi Muljono R.A. & Verpoorte R. (1998), Salicylic acid biosynthesis. In: , Biochemistry and Molecular Biology of Plant Hormones. New Comprehensive Biochemistry. Amsterdam, NL: Elsevier.
- Contin A., Heijden R. van der, Hoopen G. ten & Verpoorte R. (1998), The inoculum size triggers tryptamine or secologanin biosynthesis in a Catharanthus roseus cell culture, Plant Science 139: 205-211.
- Contin A., Heijden R. van der & Verpoorte R. (1998), Localization of secologanin in Catharanthus roseus cells, Acta Botanica Gallica : .
- Hallard D., Heijden R. van der, Contin A., Tomas Jiménéz E.M., Snoeijer W., Verpoorte R., Jensen S.R., Lopes Cardoso M.I., Pasquali G., Memelink J. & Hoge J.H.C. (1998), An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine, Phytochemical Analysis 9: 162-167.
- Contin A., Heijden R. van der, Lefeber A.W.M. & Verpoorte R. (1998), The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture, FEBS Letters 434: 413-416.
- Leech M.J., May K., Hallard D.A.C., Verpoorte R., Luca V. de & Christou P. (1998), Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: molecular diversity influences levels of expression and product accumulation, 38: 765-774.
- Ingkaninan K., Hermans-Lokkerbol A.C.J. & Verpoorte R. (1998), Comparison of some centrifugal partition chromatography systems for a general separation of plant extracts, Journal of Liquid Chromatography and Related Technologies : .
- Contin A., Heijden R. van der & Verpoorte R. (1998), The effects of phenobarbital and ketoconazole on alkaloid biosynthesis in Catharanthus roseus cell suspension cultures, Plant Physiology and Biochemistry : .
- Zuurbier K.W.M., Leser J., Berger T., Hofte A.J.P., Schröder G., Verpoorte R. & Schröder J. (1998), 4-Hydoxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates, Phytochemistry 49(7): 1945-1951.
- Carrier D.J., Beek T.A. van, Heijden R. van der & Verpoorte R. (1998), Distribution of ginkgolides and terpenoid biosynthetic activity in Ginkgo biloba, Phytochemistry 48: 89-92.
- Rech S.B., Batista C.V.F., Schripsema J., Verpoorte R. & Henriques A.T. (1998), Cell cultures of Rauvolfia sellowii: growth and alkaloid production, Plant Cell, Tissue and Organ Culture 54: 61-63.
- Zuurbier K.W.M., Fung S.Y., Scheffer J.J.C. & Verpoorte R. (1998), In-vitro prenylation of aromatic intermediates in the biosynthesis of bitter acids in Humulus lupulus, Phytochemistry 49: 2315-2322.
- Theodoridis G., Laskaris G., Jong C.F. de, Hofte A.J.P. & Verpoorte R. (1998), Determination of paclitaxel and related diterpenoids in plant extracts by high-performance liquid chromatography with UV detection in high-performance liquid chromatography-mass spectrometry, Journal of Chromatography A 802: 297-305.
- Canel C., Lopes Cardoso M.I., Whitmer S., Fits L. van der, Pasquali G., Heijden R. van der, Hoge J.H.C. & Verpoorte R. (1998), Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus, Planta 205: 414-419.
- Budi Muljono R.A., Looman A.M.G., Verpoorte R. & Scheffer J.J.C. (1998), Assay of salicylic acid and related compounds in plant cell cultures by capillary GC, Phytochemical Analysis 9: 35-38.
- Verpoorte R., Heijden R. van der, Hoopen G. ten & Memelink J. (1998), Metabolic engineering to improve plant secondary metabolite production, Plant Tissue Culture and Biotechnology 4: 3-20.
- Hofte A.J.P., Hoeven R.A.M. van der, Fung S.Y., Verpoorte R., Tjaden U.R. & Greef J. van der (1998), Characterization of hop acids by liquid chromatography with negative electrospray ionization mass spectrometry, Journal American Society Brewing Chemists 56(3): 118-122.
- Taesotikul T., Panthong A., Kanjanapothi D., Verpoorte R. & Scheffer J.J.C. (1998), Neuropharmacological activities of the crude alkaloidal fraction from stems of Tabernaemontana pandacaqui Poir, Ethnopharmacology 62: 229-234.
- Editor
- Voorzitter Raad van Toezicht
- Executive Editor
- Editor