Olga Snip
PhD candidate/guest
- Name
- O.S.C. Snip MSc
- Telephone
- +31 71 527 6582
- o.s.c.snip@lacdr.leidenuniv.nl
Olga Snip (M.Sc.) is a PhD student at the Division of Biopharmaceutics.
Olga Snip is a PhD student in Biopharmaceutical Sciences interested in atherosclerotic cardiovascular disease. Particularly, the targeting of macrophages to induce atherosclerosis regression. Her present studies aim to validate the importance of macrophage ABCA1-mediated cholesterol efflux as a possible strategy for the induction of atherosclerosis regression. In addition, Olga is a member of the LACDR Institute Council, which offers the LACDR Management Team solicited and unsolicited advice on various matters of policy. Before commencing her PhD program at the Leiden University, Olga studied Biomedical Sciences at the University of Amsterdam, specializing in cardiovascular diseases and experimental immunology.
PhD candidate/guest
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Pharmacology
- Hoekstra M., Snip O.S.C., Janusz P., Bernabé Kleijn M.N.A., Truitt E.R., Sullivan B.D., Schmidt T.A., Jay G.D. & Eck M. van (2024), Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low-density lipoprotein receptor knockout mice, Journal of Physiology London 602(9): 1939-1951.
- Snip O.S.C., Hoekstra M., Zhang Y., Geerling J.J. & Eck M. van (2022), 2-Hydroxypropyl-beta-cyclodextrin treatment does not induce atherosclerotic lesion regression in Western-type diet-fed apolipoprotein E knockout mice, Biomolecules 12(9): 1205.
- Ouweneel A.B., Reiche M.E., Snip O.S.C., Wever R., Wel E.J. van der, Schaftenaar F.H., Kauerova S., Lutgens E., Eck M. van & Hoekstra M. (2022), Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis, Journal of Cell Science 135(5): jcs.258901.
- Ouweneel A.B., Reiche M.E., Snip O.S.C., Wever R., Wel E.J. van der, Schaftenaar F.H. & Kauerova S.: Lutgens E.: Eck M. van Hoekstra M. (2021), Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis, Journal of Cell Science 135(5): jcs258901.
- Hoekstra M., Snip O.S.C. & Eck M. van (2019), Letter by Hoekstra et al Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages", Circulation 139(16): 1981-1982.
- Snip O.S.C., Ouweneel A.B., Wever R., Schaftenaar F.H., Cejkova S., Eck M. van & Hoekstra M. (2019), Apolipoprotein A1 modulates the ability of bone marrow to facilitate lymphocyte production after transplantation into Ldl receptor knockout mice, Atherosclerosis 287: E107-E107.
- Ouweneel A.B., Hoekstra M., Wel E.J. van der, Schaftenaar F.H., Snip O.S.C., Hassan J., Korporaal S.J.A. & Eck M. van (2018), Hypercholesterolemia impairs megakaryopoiesis and platelet production in scavenger receptor BI knockout mice, Atherosclerosis 282: 176-182.
- Snip O.S.C., Hoekstra M., Zhao Y., Calpe-Berdiel L., Vulve J., Carles Escola-Gil J., Foks A., Sluis R.J. van der, Blanco-Vaca F., Berkel T.J.C. van, Kuivenhoven J. & Eck M. van (2018), Reduced systemic inflammation and increased reverse cholesterol transport together drive leukocyte ABCA1-mediated protection against atherosclerosis, Atherosclerosis 275: e43-e44.
- Snip O.S.C., Geerling J.J. & Eck M. van (2017), Leukocyte ABCA1 impedes progression of established atherosclerotic lesions after dietary cholesterol lowering in LDLr-/- mice, Atherosclerosis 263: E1.