Nicolas Drouin
Assistant professor
- Name
- Dr. N.F.P. Drouin
- Telephone
- +31 71 527 2727
- n.f.p.drouin@lacdr.leidenuniv.nl
Assistant professor
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Analytical Biosciences
- Drouin N., Elfrink H.L., Boers S.A., Hugten S. van, Wessels E., Vries J.J.C. de, Groeneveld G.H., Miggiels P., Puyvelde B. van, Dhaenens M., Budding A.E., Ran L., Masius R., Takats Z., Boogaerds A., Bulters M., Muurlink W., Oostvogel P., Harms A.C., Lubben M. van der & Hankemeier T. (2024), A targeted LC-MRM3 proteomic approach for the diagnosis of SARS-CoV-2 infection in nasopharyngeal swabs, Molecular and Cellular Proteomics 23(7): 100805.
- Huang L., Drouin N.F.P., Causon J., Wegrzyn A.B., Castro-Perez J., Fleming R.M., Harms A.C. & Hankemeier T. (2023), Reconstruction of glutathione metabolism in the neuronal model of rotenone-induced neurodegeneration using mass isotopologue analysis with hydrophilic interaction liquid chromatography-Zeno high-resolution multiple reaction monitoring, Analytical Chemistry 95(6): 3255-3266.
- Puyvelde B. van, Uytfanghe K., Oudenhove L. van Gabriels R., Royen T. van, Matthys A., Razavi M., Yip R., Pearson T., Drouin N.F.P., Claereboudt J., Foley D., Wardle R., Wyndham K., Hankemeier T., Jones D., Saelens X., Martens G., Stove C.P., Deforce D., Martens L., Vissers J.P.C., Anderson N.L. & Dhaenens M. (2022), Cov2MS: an automated and quantitative matrix-independent assay for mass spectrometric measurement of SARS-CoV-2 nucleocapsid protein, Analytical Chemistry 94(50): 17379-17387.
- He Y., Drouin N.F.P., Wouters B., Miggiels A.L.W., Hankemeier T. & Lindenburg P.W. (2022), Development of a fast, online three-phase electroextraction hyphenated to fast liquid chromatography-mass spectrometry for analysis of trace-level acid pharmaceuticals in plasma, Analytica Chimica Acta 1192: 339364.
- He Y., Miggiels A.L.W., Drouin N.F.P., Lindenburg P.W., Wouters B. & Hankemeier T. (2022), An automated online three-phase electro-extraction setup with machine-vision process monitoring hyphenated to LC-MS analysis, Analytica Chimica Acta 1235: 340521.
- He Y.P., Miggiels A.L.W., Wouters B., Drouin N.F.P., Guled F., Hankemeier T. & Lindenburg P.W. (2021), A high-throughput, ultrafast, and online three-phase electro-extraction method for analysis of trace level pharmaceuticals, Analytica Chimica Acta 1149: 338204.
- Puyvelde B. van, Uytfanghe K. van, Tytgat O., Oudenhove L., Gabriels R., Bouwmeester R., Daled S., Bossche T. van den, Ramasamy P., Verhelst S., Clerck L. de, Corveleyn L., Willems S., Debunne N., Wynendaele E., Spiegeleer B. de, Judak P, Roels K., Wilde L. de, Eenoo P. van, Reyns T., Cherlet M., Dumont E., Debyser G.,'Kindt R. 't, Sandra K., Gupta S., Drouin N., Harms A., Hankemeier T., Jones D.J.L., Gupta P., Lane D., Lane C.S., El Ouadi S., Vincendet J.B., Morrice N., Oehrle S., Tanna N., Silvester S., Hannam S., Sigloch F.C., Bhangu-Uhlmann A., Claereboudt J., Anderson N.L., Razavi M., Degroeve S., Cuypers L., Stove C., Lagrou K., Martens G.A., Deforce D., Martens L., Vissers J.P.C. & Dhaenens M. (2021), Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients: a community-based template assay for mass-spectrometry-based protein detection in SARS-CoV-2 patients, JACS Au 1(6): 750-765.
- Mever M. van, Willacey C.C.W., Zhang W., Drouin N.F.P., Christina A.E., Lindenburg P.W., Veldhoven J.P. D. van, Es D. van der, Harms A.C., Hankemeier T. & Ramautar R. (2021), Profiling acidic metabolites by capillary electrophoresis‐mass spectrometry in low numbers of mammalian cells using a novel chemical derivatization approach, Analytical Science Advances 3(1-2): 3-13.
- Mever M. van, Segers K.R.H., Drouin N.F.P., Guled F., Vander Heyden Y., Van Eeckhaut A., Hankemeier T. & Ramautar R. (2020), Direct profiling of endogenous metabolites in rat brain microdialysis samples by capillary electrophoresis-mass spectrometry with on-line preconcentration, 156: 104949.
- Drouin N.F.P., Mever M. van, Zhang W., Tobolkina E., Ferre S., Servais A.C., Gou M.J., Nyssen L., Fillet M., Lageveen-Kammeijer G.S.M., Nouta J., Chetwynd A.J., Lynch I., Thorn J.A., Meixner J., Lossner C., Taverna M., Liu S., Tran N.T., Francois Y., Lechner A., Nehm R., Banni G.A.D., Nasreddine R., Colas C., Lindner H.H., Faserl K., Neususs C., Nelke M., Lammerer S., Perrin C., Bich-Muracciole C., Barbas C., Lopez Gonzalvez A., Guttman A., Szigeti M., Britz-McKibbin P., Kroezen Z., Shanmuganathan M., Nemes P., Portero E.P., Hankemeier T., Codesido S., Gonzalez-Ruiz V., Rudaz S. & Ramautar R. (2020), Capillary electrophoresis-mass spectrometry at trial by Metabo-Ring: Effective electrophoretic mobility for reproducible and robust compound annotation, Analytical Chemistry 92(20): 14103-14112.
- Drouin N.F.P., Kloots T.N., Schappler J., Rudaz S., Kohler I., Harms A.C., Lindenburg P.W. & Hankemeier T. (2019), Electromembrane Extraction of Highly Polar Compounds: Analysis of Cardiovascular Biomarkers in Plasma, Metabolites 10(1): 4.