Matthijs Vlasveld
PhD candidate / Guest
- Name
- M.P. Vlasveld MSc
- Telephone
- +31 71 527 2727
- m.p.vlasveld@lacdr.leidenuniv.nl
Matthijs Vlasveld studied Bio-Pharmaceutical Sciences at Leiden University. During his MSc program, he specialized in toxicology, with a focus on cellular mechanisms of hepatotoxicity. The first internship of Matthijs focused on the synergistic adverse reaction between the inflammatory response and carbamazepine as hepatotoxic drug and genes that regulate this response. To obtain a broader experience in the field of cell biology, he went to Konstanz to learn more about mechanistic research and different cell types. In May 2018, Matthijs started his PhD at the division of drug discovery and safety. His project focusses on the mechanisms behind adverse outcome by drug-like chemicals and the development of a tool that better predicts biomarkers that indicate these adverse reactions.
PhD candidate / Guest
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Toxicology
- Vlasveld M.P., Callegaro G., Fisher C., Eakins J., Walker P., Lok S., Oost S. van, Jong B. de, Pellegrino Coppola D., Burger G.A., Wink S. & Water B. van de (2024), The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability, Liver International 44(3): 760-775.
- Hosseini R., Vlasveld M.P., Willemse J.J., Water B. van de, Le Dévédec S.E. & Wolstencroft K.J. (2023), FAIR high content screening in bioimaging, Scientific Data 10(1): 462.
- Wijaya L.S., Rau C., Braun T.S., Marangoz S., Spegg V., Vlasveld M., Albrecht W., Brecklinghaus T., Kamp H., Beltman J.B., Hengstler J.G., Water B. van de, Leist M. & Schildknecht S. (2021), Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes, Cell Biology and Toxicology : .
- Hiemstra S., Niemeijer M., Koedoot E., Wink S., Pip J.E., Vlasveld M., Zeeuw E. de , Os B. van, White A. & Water B. van de (2017), Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage, Chemical Research in Toxicology 30(4): 923-933.