Mariana Avalos Garcia
Postdoc
- Name
- Dr. M. Avalos Garcia
- Telephone
- +31 71 527 4294
- m.avalos.garcia@biology.leidenuniv.nl
- ORCID iD
- 0000-0001-9891-924X
I obtained my Bachelor (Pharmaceutical-Biological Chemistry) and Master’s degree (Biochemistry) in Mexico city from the National Autonomous University of Mexico (UNAM). My Master’s project involved isolating and identifying novel antibiotic compounds from Streptomyces strains. My PhD project focused on studying and identifying volatile compounds released by Streptomyces with antibiotic activity, as well as its mode of action and the mechanism of resistance of target Bacteria.
Postdoc
- Science
- Instituut Biologie Leiden
- IBL Microbial Sciences
Project Leader
- Science
- Instituut Biologie Leiden
- IBL Microbial Sciences
- Bakker A.T., Kotsogianni I., Avalos Garcia M., Punt J.M., Liu B., Piermarini D., Gagestein B., Slingerland C.J., Zhang L., Willemse J.J., Ghimire L.B., Berg Richard J.H.B.N. van den, Janssen A.P.A., Ottenhoff T.H.M., Boeckel C.A.A. van, Wezel G.P. van, Ghilarov D., Martin N.I. & Stelt M. van der (2024), Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria, Nature Chemistry 16: 1462-1472.
- Garbeva P., Avalos M., Ulanova D., Wezel G.P. van & Dickschat J.S. (2023), Volatile sensation: the chemical ecology of the earthy odorant geosmin, Environmental Microbiology 25(9): 1565-1574.
- Bakker A.T., Kotsogianni A.I., Mirenda L., Straub V.M., Avalos Garcia M., Berg R.J.B.H.N. van den, Florea B.I., Wezel G.P. van, Janssen A.P.A., Martin N.I. & Stelt M. van der (2023), Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA, Journal of the American Chemical Society 145(2): 1136-1143.
- Avalos Garcia M., Garbeva P., Vader L., Wezel G.P. van, Dickschat J. & Ulanova D. (2022), Biosynthesis, evolution and ecology of microbial terpenoids, Natural Product Reports 39(2): 249-272.
- Bakker A.T., Kotsogianni A.I., Mirenda L., Straub V.M., Avalos Garcia M., Berg R.J.B.H.N. van den, Florea B.I., Wezel G.P. van, Janssen A.P.A., Martin N.I. & Stelt M. van der (2022), Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA, Journal of the American Chemical Society 145(2): 1136-1143.
- Avalos M., Garbeva P., Raaijmakers J.M. & Wezel G.P. van (2020), Production of ammonia as a low-cost and long-distance antibiotic strategy by Streptomyces species, The ISME Journal 14(2): 569-583.
- Avalos Garcia M. (24 September 2019), Volatile compounds from Actinobacteria as mediators of microbial interactions (Dissertatie. Institute of Biology Leiden (IBL), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Wezel G.P. van, Garbeva P.
- Martín-Sánchez L., Singh K.S., Avalos M., Wezel G.P. van, Dickschat J.S. & Garbeva P. (2019), Phylogenomic analyses and distribution of terpene synthases among Streptomyces, Beilstein Journal of Organic Chemistry 15: 1181-1193.
- Avalos Garcia M., Wezel G.P. van, Raaijmakers J.M. & Garbeva P. (2018), Healthy scents: microbial volatiles as new frontier in antibiotic research?, Current Opinion in Microbiology 45: 84-91.
- Avalos M., Boetzer M., Pirovano W., Arenas N.E., Douthwaite S. & Wezel G.P. van (2018), Complete genome sequence of escherichia coli AS19, an antibiotic-sensitive variant of E. coli strain B REL606, Genome Announcements 6(18): e00385-18.