Laura Zwep
Assistant professor
- Name
- Dr. L.B. Zwep
- Telephone
- +31 71 527 2727
- l.b.zwep@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0002-6817-2859
-
Assistant professor
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Pharmacology
- Zwep L.B., Guo T., Nagler T.W., Knibbe C.A.J., Meulman J.J. & Hasselt J.G.C. van (2024), Virtual patient simulation using copula modeling, Clinical Pharmacology & Therapeutics 115(4): 795-804.
- Guo Y., Guo T., Knibbe C.A.J., Zwep L.B. & Hasselt J.G.C. van (2024), Generation of realistic virtual adult populations using a model-based copula approach, Journal of Pharmacokinetics and Pharmacodynamics 51: 735-746.
- Hartog I. den, Zwep L.B., Meulman J.J., Hankemeier T., Garde E.M.W. van de & Hasselt J.G.C. van (2024), Longitudinal metabolite profiling of Streptococcus pneumoniae-associated community-acquired pneumonia, Metabolomics 20(2): 35.
- Hartog I. den, Karu N., Zwep L.B., Voorn P.G., Garde E.M.W. van de, Hankemeier T. & Hasselt C.J.G. van (2023), Differential metabolic host response to pathogens associated with community-acquired pneumonia, Metabolism open 18: 100239.
- Zwep L.B. (12 April 2023), Statistical learning for complex data to enable precision medicine strategies (Dissertatie. Leiden Academic Centre for Drug Research (LADCR), Faculty of Science, Leiden University). Supervisor(s) and Co-supervisor(s): Meulman J.J., Hasselt J.G.C. van.
- Zwep L.B., Duisters K.L.W., Jansen M., Guo T., Meulman J.J., Upadhyay P. & Hasselt J.G.C. (2021), Identification of high‐dimensional omics‐derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling, CPT: Pharmacometrics and Systems Pharmacology 10(4): 350-361.
- Hartog I. den, Zwep L.B., Vestjens S.M.T., Harms A.C., Voorn G.P., Lange D.W. de, Bos W.J.W., Hankemeier T., Garde E.M.W. & Hasselt J.G.C. van (2021), Metabolomic profiling of microbial disease etiology in community-acquired pneumonia, PLoS ONE 16(6): e0252378.
- Zwep L.B., Haakman Y., Duisters K.L.W., Meulman J.J., Liakopoulos A. & Hasselt J.G.C. van (2021), Identification of antibiotic collateral sensitivity and resistance interactions in population surveillance data, JAC-Antimicrobial Resistance 3(4): dlab175.
- Goulooze S.C., Zwep L.B., Vogt J.E., Krekels E.H.J., Hankemeier T., Anker J.N. van den & Knibbe C.A.J. (2020), Beyond the randomized clinical trial: innovative data science to close the pediatric evidence gap, Clinical Pharmacology & Therapeutics 107(4): 786-795.
- Guo T.J., Hest R.M. van, Zwep L.B., Roggeveen L.F., Fleuren L.M., Bosman R.J., Voort P.H.J. van der, Girbes A.R.J., Mathot R.A.A., Elbers P.W.G. & Hasselt J.G.C. van (2020), Optimizing predictive performance of bayesian forecasting for vancomycin concentration in intensive care patients, Pharmaceutical Research 37: 171.