Jacco Wallinga
Professor Mathematic modelling of infectious diseases
- Name
- Prof.dr. J. Wallinga
- Telephone
- +31 71 526 9111
- j.wallinga@lumc.nl
- ORCID iD
- null

Jacco Wallinga is professor of mathematical modelling of infectious diseases. He is also affiliated with the National Institute for Public Health and the Environment (RIVM) as head of the unit Modelling Infectious Diseases.
More information about Jacco Wallinga
Jacco Wallinga is professor of mathematical modelling of infectious diseases. He is also affiliated with the National Institute for Public Health and the Environment (RIVM) as head of the unit Modelling Infectious Diseases.
Infectious disease control
How can we predict the spread of an infectious disease among the human population? And if we take measures to control the spread, how effective should these interventions be? How many lives will be saved by the current vaccination programmes? These questions are central to research for infectious disease control. With mathematical, statistical and computational approaches we answer these questions.
Academic career
Jacco Wallinga obtained his MSc and PhD at the Wageningen University. The title of his PhD thesis (December 11th, 1998) is: ‘Dynamics of Weed Populations: spatial pattern formation and implications for control’. Wallinga specialised in the field of population biology of infectious diseases at the National Institute for Public Health and the Environment (RIVM). He was appointed professor mathematical modelling of infectious diseases at the Leiden University Medical Centre. The title of his inaugural lecture is ‘Beyond the epidemic curve: models for infectious disease control’ (October 21st 2016).
Wallinga has published over 100 scientific articles and book chapters (see also the website of Harvard - School of Public Health).
He has been member of the Health Council of the Netherlands. He was on the epidemic board of the journal Epidemiology. He advises several national and intergovernmental agencies such as the WHO.
Professor Mathematic modelling of infectious diseases
- Faculteit Geneeskunde
- Divisie 4
- Biomedical Data Sciences
Contact
- Miyazawa, S.; Wong, T.S.; Ito, G.; Iwamoto, R.; Watanabe, K.; , M. van boven; Wallinga, J. & Miura, F. (2024), Wastewater-based reproduction numbers and projections of COVID-19 cases in three areas in Japan, November 2021 to December 2022, EUROSURVEILLANCE 29(8).
- Konstantinovski, M.; Geest, C. van; Bruijning, M.; Keizer, L.K.D.; Wallinga, J.; Burgel, N. van & Veldkamp, K.E. (2024), Rate of nosocomial MRSA transmission evaluated via contact screening, Antimicrobial Resistance and Infection Control 13(1).
- Munday, J.D.; Atkins, K.E.; Klinkenberg, D.; Meurs, M.; Fleur, E.; Hahné, S.J.; Wallinga, J. & Hoek, A.J. van (2024), Estimating the risk and spatial spread of measles in populations with high MMR uptake: Using school-household networks to understand the 2013 to 2014 outbreak in the Netherlands, PLoS Medicine 21(10).
- Boer, P.T. de; Werkhoven, C.H. van; Hoek, A.J. van; Knol, M.J.; Sanders, E.A.M.; Wallinga, J.; Melker, H.E. de & Steens, A. (2024), Higher-valency pneumococcal conjugate vaccines in older adults, taking into account indirect effects from childhood vaccination: a cost-effectiveness study for the Netherlands, BMC Medicine 22(1).
- Reitsema, M.; Wallinga, J.; Sighem, A.I. van; Bezemer, D.; Valk, M. van der; Aar, F. van; Heijne, J.C.M.; Hoornenborg, E.; Rozhnova, G.; Benthem, B. van & Xiridou, M. (2024), Impact of Varying Pre-exposure Prophylaxis Programs on HIV and Neisseria gonorrhoeae Transmission Among MSM in the Netherlands: A Modeling Study.
- Jeong, Y.D.; Hart, W.S.; Thompson, R.N.; Ishikane, M.; Nishiyama, T.; Park, H.; Iwamoto, N.; Sakurai, A.; Suzuki, M.; Aihara, K.; Watashi, K.; Coul, E. op de; Ohmagari, N.; Wallinga, J.; Iwami, S. & Miura, F. (2024), Modelling the effectiveness of an isolation strategy for managing mpox outbreaks with variable infectiousness profiles, Nature Communications 15(1).
- Klinkenberg, D.; Backer, J.; Keizer, N. de; Wallinga, J. & Jacco, W. (2024), Projecting COVID-19 intensive care admissions for policy advice, the Netherlands, February 2020 to January 2021, EUROSURVEILLANCE 29(10).
- Loedy, N.; Wallinga, J.; Hens, N. & Torneri, A. (2024), Repetition in social contacts: implications in modelling the transmission of respiratory infectious diseases in pre-pandemic and pandemic settings, Proceedings of the Royal Society B: Biological Sciences 291(2027).
- Jarvis, C.I.; Coletti, P.; Backer, J.A.; Munday, J.D.; Faes, C.; Beutels, P.; Althaus, C.L.; Low, N.; Wallinga, J.; Hens, N. & Edmunds, W.J. (2024), Social contact patterns following the COVID-19 pandemic: a snapshot of post-pandemic behaviour from the CoMix study, Epidemics: The Journal on Infectious Disease Dynamics 48.
- Jung, S.M.; Miura, F.; Murayama, H.; Funk, S.; Wallinga, J.; Lessler, J. & Endo, A. (2024), Dynamic Landscape of Mpox Importation Risks Driven by Heavy-Tailed Sexual Contact Networks Among Men Who Have Sex With Men in 2022, The Journal of Infectious Diseases.
- Backer, J.A.; Vos, E.R.A.; Hartog, G. den; Hagen, C.C.E. van; Melker, H.E. de; Klis, F.R.M. van der & Wallinga, J. (2024), Contact behaviour before, during and after the COVID-19 pandemic in the Netherlands: evidence from contact surveys, 2016 to 2017 and 2020 to 2023, EUROSURVEILLANCE 29(43).
- Leung, K.Y.; Metting, E.; Ebbers, W.; Veldhuijzen, I.; Andeweg, S.P.; Luijben, G.; Bruin, M. de; Wallinga, J. & Klinkenberg, D. (2024), Effectiveness of a COVID-19 contact tracing app in a simulation model with indirect and informal contact tracing, Epidemics: The Journal on Infectious Disease Dynamics 46.
- Xiridou, M.; Heijne, J.; Adam, P.; Coul, E.O. de; Matser, A.; Wit, J. de; Wallinga, J. & Benthem, B. van (2022), How the disruption in sexually transmitted infection care due to the COVID-19 Pandemic could lead to increased sexually transmitted infection transmission among men who have sex with men in The Netherlands , Sexually Transmitted Diseases 49(2): 145-153.
- Ainslie, K.E.C.; Backer, J.A.; Boer, P.T. de; Hoek, A.J. van; Klinkenberg, D.; Altes, H.K.; Leung, K.Y.; Melker, H. de; Miura, F. & Wallinga, J. (2022), A scenario modelling analysis to anticipate the impact of COVID-19 vaccination in adolescents and children on disease outcomes in the Netherlands, summer 2021, Eurosurveillance 27(44): 28-37.
- Klinkenberg, D.; Hoek, A.J. van; Veldhuijzen, I.; Hahne, S. & Wallinga, J. (2022), Social clustering of unvaccinated children in schools in the Netherlands, Epidemiology & Infection 150.
- Miura, F.; Ewijk, C.E. van; Backer, J.A.; Xiridou, M.; Franz, E.; Coul, E.O. de; Brandwagt, D.; Cleef, B. van; Rijckevorsel, G. van; Swaan, C.; Hof, S. van den & Wallinga, J. (2022), Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022, Eurosurveillance 27(24).
- McDonald, S.A.; Lagerweij, G.R.; Boer, P. de; Melker, H.E. de; Pijnacker, R.; Gras, L.M.; Kretzschmar, M.E.; Hartog, G. den; Gageldonk-Lafeber, A.B. van; Hof, S. van den; Wallinga, J. & RIVM COVID-19 Surveillance Epidemi (2022), The estimated disease burden of acute COVID-19 in the Netherlands in 2020, in disability-adjusted life-years, European Journal of Epidemiology 37(10): 1035-1047.
- McDonald, S.A.; Wijhe, M. van; Gier, B. de; Altes, H.K.; Vlaminckx, B.J.M.; Hahne, S. & Wallinga, J. (2022), The dynamics of scarlet fever in The Netherlands, 1906-1920, Royal Society Open Science 9(11).
- Backer, J.A.; Eggink, D.; Andeweg, S.P.; Veldhuizen, I.K.; Maarseveen, N. van; Vermaas, K.; Vlaemynck, B.; Schepers, R.; Hof, S. van den; Reusken, C.B.E.M. & Wallinga, J. (2022), Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021, Eurosurveillance: Europe's journal on infectious disease surveillance, epidemiology, prevention and control 27(6).
- Kremer, C.; Ganyani, T.; Chen, D.X.; Torneri, A.; Faes, C.; Wallinga, J. & Hens, N. (2020), Authors' response: estimating the generation interval for COVID-19 based on symptom onset data.
- Boer, P.T. de; Backer, J.A.; Hoek, A.J. van & Wallinga, J. (2020), Vaccinating children against influenza, BMC Medicine 18(1).
- Gaalen, R.D. van; Altorf-van der Kuil, W.; Wegdam-Blans, M.C.A.; Diaz, J.M.A.; Beauchamp, M.E.; Pinedo, L.E.C.; Greeff, S.C. de & Wallinga, J. (2020), Determination of the time-dependent association between ciprofloxacin consumption and ciprofloxacin resistance using a weighted cumulative exposure model compared with standard models, Journal of Antimicrobial Chemotherapy 75(8): 2326-2333.
- Dam, A.S.G. van; Woudenberg, T.; Melker, H.E. de; Wallinga, J. & Hahne, S.J.M. (2020), Effect of vaccination on severity and infectiousness of measles during an outbreak in the Netherlands, 2013-2014, Epidemiology & Infection 148.
- Hoogink, J.; Verelst, F.; Kessels, R.; Hoek, A.J. van; Timen, A.; Willem, L.; Beutels, P.; Wallinga, J. & Wit, G.A. de (2020), Preferential differences in vaccination decision-making for oneself or one's child in The Netherlands, BMC Public Health 20(1).
- Ganyani, T.; Kremer, C.; Chen, D.X.; Torneri, A.; Faes, C.; Wallinga, J. & Hens, N. (2020), Estimating the generation interval for coronavirus disease (COVID-19) based on symptom onset data, march 2020, Eurosurveillance 25(17): 12-19.
- Tindale, L.C.; Stockdale, J.E.; Coombe, M.; Garlock, E.S.; Lau, W.Y.V.; Saraswat, M.; Zhang, L.X.; Chen, D.X.; Wallinga, J. & Colijn, C. (2020), Evidence for transmission of COVID-19 prior to symptom onset, eLife 9.
- Reitsema, M.; Heijne, J.; Visser, M.; Sighem, A. van; Loeff, M.S. van der; Coul, E.L.M. op de; Bezemer, D.; Wallinga, J.; Benthem, B.H.B. van & Xiridou, M. (2020), Impact of frequent testing on the transmission of HIV andN. gonorrhoeaeamong men who have sex with men, Sexually Transmitted Infections 96(5): 361-367.
- Backer, J.A.; Klinkenberg, D. & Wallinga, J. (2020), Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020, Eurosurveillance 25(5): 10-15.
- Gostic, K.M.; McGough, L.; Baskerville, E.B.; Abbott, S.; Joshi, K.; Tedijanto, C.; Kahn, R.; Niehus, R.; Hay, J.A.; Salazar, P.M. de; Hellewell, J.; Meakin, S.; Munday, J.D.; Bosse, N.I.; Sherrat, K.; Thompson, R.N.; White, L.F.; Huisman, J.S.; Scire, J.; Bonhoeffer, S.; Stadler, T.; Wallinga, J.; Funk, S.; Lipsitch, M. & Cobey, S. (2020), Practical considerations for measuring the effective reproductive number, R-t, PLoS Computational Biology 16(12).
- Reitsema, M.; Hoek, A.J. van; Loeff, M.S. van der; Hoornenborg, E.; Sighem, A. van; Wallinga, J.; Benthem, B. van & Xiridou, M. (2020), Preexposure prophylaxis for men who have sex with men in the Netherlands, AIDS 34(4): 621-630.
- Asmuth, E.G.J. von; Brockhoff, H.J.; Wallinga, J. & Visser, L.G. (2019), S. typhi Vi capsular polysaccharide vaccine-induced humoral immunity in travellers with immunosuppressive therapy for rheumatoid disease, Journal of Travel Medicine 26(1).
- Uzorka, J.W.; Wallinga, J.; Kroft, L.J.M.; Ottenhoff, T.H.M. & Arend, S.M. (2019), Radiological Signs of Latent Tuberculosis on Chest Radiography: A Systematic Review and Meta-Analysis, Open Forum Infectious Diseases 6(7).
- Soetens, L.; Backer, J.A.; Hahne, S.; Binnendijk, R. van; Gouma, S. & Wallinga, J. (2019), Visual tools to assess the plausibility of algorithm-identified infectious disease clusters: an application to mumps data from the Netherlands dating from January 2009 to June 2016, Eurosurveillance 24(12): 26-36.
- Backer, J.A.; , M. van boven; Hoek, W. van der & Wallinga, J. (2019), Vaccinating children against influenza increases variability in epidemic size, Epidemics 26: 95-103.
- Wijhe, M. van; Boer, P.T. de; Jong, H.J. de; Vliet, H. van; Wallinga, J. & Postma, M.J. (2019), Trends in governmental expenditure on vaccination programmes in the Netherlands, a historical analysis, Vaccine 37(38): 5698-5707.
- Backer, J.A.; Wallinga, J.; Meijer, A.; Donker, G.A.; Hoek, W. van der & , M. van boven (2019), The impact of influenza vaccination on infection, hospitalisation and mortality in the Netherlands between 2003 and 2015, Epidemics 26: 77-85.
- Asmuth, E.G.J. von; Brockhoff, H.J.; Wallinga, J. & Visser, L.G. (2019), S. typhi Vi capsular polysaccharide vaccine-induced humoral immunity in travellers with immunosuppressive therapy for rheumatoid disease, Journal of Travel Medicine 26(1).
- Kassteele, J. van de; Eilers, P.H.C. & Wallinga, J. (2019), Nowcasting the Number of New Symptomatic Cases During Infectious Disease Outbreaks Using Constrained P-spline Smoothing, Epidemiology 30(5): 737-745.
- Peppel, R.J. van de; Beek, M.T. van der; Visser, L.G.; Boer, M.G.J. de & Wallinga, J. (2019), Managing invasive aspergillosis in haematological patients in the era of resistance polymerase chain reaction and increasing triazole resistance: A modelling study of different strategies, International Journal of Antimicrobial Agents 53(3): 284-293.
- Man, I.; Auranen, K.; Wallinga, J. & Bogaards, J.A. (2019), Capturing multiple-type interactions into practical predictors of type replacement following human papillomavirus vaccination, Philosophical Transactions B: Biological Sciences 374(1773).
- Hoang, T.; Coletti, P.; Melegaro, A.; Wallinga, J.; Grijalva, C.G.; Edmunds, J.W.; Beutels, P. & Hens, N. (2019), A Systematic Review of Social Contact Surveys to Inform Transmission Models of Close-contact Infections, Epidemiology 30(5): 723-736.
- Winter, A.K.; Martinez, M.E.; Cutts, F.T.; Moss, W.J.; Ferrari, M.J.; McKee, A.; Lessler, J.; Hayford, K.; Wallinga, J. & Metcalf, C.J.E. (2018), Benefits and Challenges in Using Seroprevalence Data to Inform Models for Measles and Rubella Elimination, Journal of Infectious Diseases 218(3): 355-364.
- Monge, S.; Benschop, K.; Soetens, L.; Pijnacker, R.; Hahne, S.; Wallinga, J. & Duizer, E. (2018), Echovirus type 6 transmission clusters and the role of environmental surveillance in early warning, the Netherlands, 2007 to 2016, Eurosurveillance 23(45): 11-20.
- Wijhe, M. van; McDonald, S.A.; Melker, H.E. de; Postma, M.J. & Wallinga, J. (2018), Estimating the Population-Level Effectiveness of Vaccination Programs in the Netherlands, Epidemiology 29(2): 215-223.
- Man, I.; Wallinga, J. & Bogaards, J.A. (2018), Inferring Pathogen Type Interactions Using Cross-sectional Prevalence Data: Opportunities and Pitfalls for Predicting Type Replacement, Epidemiology 29(5): 666-674.
- Wijn, D.H.; Groeneveld, G.H.; Vollaard, A.M.; Muller, M.; Wallinga, J.; Gelderblom, H. & Smit, E.F. (2018), Influenza vaccination in patients with lung cancer receiving anti-programmed death receptor 1 immunotherapy does not induce immune-related adverse events, European Journal of Cancer 104: 182-187.
- Wallinga, J. (2018), Metropolitan versus small-town influenza, Science 362(6410): 29-30.
- Wijhe, M. van; Tulen, A.D.; Altes, H.K.; McDonald, S.A.; Melker, H.E. de; Postma, M.J. & Wallinga, J. (2018), Quantifying the impact of mass vaccination programmes on notified cases in the Netherlands, Epidemiology and Infection 146(6): 716-722.
- Soetens, L.; Klinkenberg, D.; Swaan, C.; Hahne, S. & Wallinga, J. (2018), Real-time Estimation of Epidemiologic Parameters from Contact Tracing Data During an Emerging Infectious Disease Outbreak, Epidemiology 29(2): 230-236.
- Klinkenberg, D.; Hahne, S.J.M.; Woudenberg, T. & Wallinga, J. (2018), The Reduction of Measles Transmission During School Vacations, Epidemiology 29(4): 562-570.
- Woudenberg, T.; Binnendijk, R.S. van; Sanders, E.A.M.; Wallinga, J.; Melker, H.E. de; Ruijs, W.L.M. & Hahne, S.J.M. (2017), Large measles epidemic in the Netherlands, May 2013 to March 2014: changing epidemiology, Eurosurveillance 22(3): 11-19.
- Worby, C.J.; Wallinga, J.; Lipsitch, M. & Goldstein, E. (2017), Population effect of influenza vaccination under co-circulation of non-vaccine variants and the case for a bivalent A/H3N2 vaccine component, Epidemics 19: 74-82.
- Klinkenberg, D.; Backer, J.A.; Didelot, X.; Colijn, C. & Wallinga, J. (2017), Simultaneous inference of phylogenetic and transmission trees in infectious disease outbreaks, PLoS Computational Biology 13(5).
- Soetens, L.; Hahne, S. & Wallinga, J. (2017), Dot map cartograms for detection of infectious disease outbreaks: an application to Q fever, the Netherlands and pertussis, Germany, Eurosurveillance 22(26): 23-29.
- Gaalen, R.D. van; Kassteele, J.V. van de; Hahne, S.J.M.; Bruijning-Verhagen, P. & Wallinga, J. (2017), Determinants of Rotavirus Transmission A Lag Nonlinear Time Series Analysis, Epidemiology 28(4): 503-513.
- Xiridou, M.; Lugner, A.; Vries, H.J.C. de; Bergen, J.E.A.M. van; Gotz, H.M.; Benthem, B.H.B. van; Wallinga, J. & Sande, M.A.B. van der (2016), Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands, Sexually Transmitted Diseases 43(9): 542-548.
- Afdelingshoofd Modellering van Infectieziekten