Gerwin Spijksma
Analyst
- Name
- Ing. G.K. Spijksma
- Telephone
- +31 71 527 4321
- spijksma@chem.leidenuniv.nl
Analyst
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Analytical Biosciences
- Aart L.T. van der, Spijksma G.K., Harms A.C., Vollmer W., Hankemeier T. & Wezel G.P. van (2018), High-Resolution analysis of the Peptidoglycan composition in Streptomyces coelicolor, Journal of Bacteriology 200(20): e00290.
- Massink A., Holzheimer M., Hölscher A., Louvel J., Guo D., Spijksma G., Hankemeier T. & IJzerman A.P. (2015), Mass spectrometry-based ligand binding assays on adenosine A1 and A2A receptors, Purinergic Signalling 11(4): 581-594.
- Kloet F.M. van der, Tempels F.W.A., Ismail N., Heijden R. van der, Kasper P.T., Rojas-Cherto M., Doorn R. van, Spijksma G., Koek M., Greef J. van der, Mäkinen V.P., Forsblom C., Holthöfer H., Groop P.H., Reijmers T.H. & Hankemeier T. (2012), Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study), Metabolomics 2012(8): 109-119.
- Zhu C., Dane A., Spijksma G.K., Wang M., Greef J. van der, Luo G.A., Hankemeier T. & Vreeken R.J. (2012), An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column, Journal of Chromatography A 1220: 26-34.
- Hu C., Wei H., Hoek A.M. van den, Wang M., Heijden R. van der, Spijksma G.K., Reijmers T.H., Bouwman J., Wopereis S., Havekes L.M., Verheij E., Hankemeier T., Xu G. & Greef J. van der (2011), Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice, PLoS ONE 6(5): e19423.
- Mustafa N.R., Kim H.K., Choi Y.H., Erkelens C., Lafeber A.W.M., Spijksma G.K., Heijden R. van der & Verpoorte R. (2009), Biosynthesis of salicylic acid in fungus elicited Catharanthus roseus cells, Phytochemistry 70(4): 532-539.
- Wang J., Heijden R. van der, Spijksma G.K., Reijmers T., Wang M., Xu G., Hankemeier T. & Greef J. van der (2009), Alkaloid profiling of the Chinese herbal medicine Fuzi by combination of matrix-assisted laser desorption ionization mass spectrometry with liquid chromatography-mass spectrometry, Journal of Chromatography A 1216(11): 2169-2178.
- Hu C., Dommelen J., Heijden R. van der, Spijksma G., Reijmers T.H., Wang M., Slee E., Lu X., Xu G., Greef J. van der & Hankemeier T. (2008), RPLC-ion-trap-FTMS method for lipid profiling of plasma: method validation and application to p53 mutant mouse model, Journal of Proteome Research 7(11): 4982-4991.
- Hart B.A. 't, Vogels J.T.W.E., Spijksma G., Brok H.P.M., Polman C. & Greef J. van der (2003), 1H-NMR spectroscopy combined with pattern recognition analysis reveals characteristic chemical patterns in urines of MS patients and non-human primates with MS-like disease, Journal of the Neurological Sciences 212(1-2): 21-30.
- Lamers R.J.A.N., Groot J. de, Spies-Faber E.J., Jellema R.H., Kraus V.B., Verzijl N., TeKoppele J.M., Spijksma G.K., Vogels J.T.W.E., Greef J. van der & Nesselrooij J.H.J. van (2003), Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic guinea pigs, Journal of Nutrition 133(6): 1776-1780.