Patient-oriented research is fascinating. The successful clinical implementation of new findings and approaches gives a lot of satisfaction. A source of inspiration is the international collaboration, which is essential to optimize the results of organ and hematopoietic stem cell transplantation. Leiden plays a pivotal role in the selection of the best donor via two foundations initiated by my predessor and teacher Jon van Rood: Eurotransplant and Europdonor. The final aim of our studies is to induce donor specific transplantation tolerance, which implies manipulation of the immune system of the recipient in such a way that the transplanted organ is accepted as part of the self whereas the immune response to infectious agents and cancer cells remains intact. The immune mechanisms involved immunological acceptance of the fetus by the mother during successful pregnancy may lead to novel approaches to induce transplantation tolerance.

More information about Franciscus Claas

Patient-oriented research is fascinating. The successful clinical implementation of new findings and approaches gives a lot of satisfaction. A source of inspiration is the international collaboration, which is essential to optimize the results of organ and hematopoietic stem cell transplantation. Leiden plays a pivotal role in the selection of the best donor via two foundations initiated by my predessor and teacher Jon van Rood: Eurotransplant and Europdonor. The final aim of our studies is to induce donor specific transplantation tolerance, which implies manipulation of the immune system of the recipient in such a way that the transplanted organ is accepted as part of the self whereas the immune response to infectious agents and cancer cells remains intact. The immune mechanisms involved immunological acceptance of the fetus by the mother during successful pregnancy may lead to novel approaches to induce transplantation tolerance.

The title of his inaugural lecture was 'Het subtiele verschil tussen mijn en dijn'.

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