Ewout Steyerberg
Professor Clinical Biostatistics and Medical Decision Making
- Name
- Prof.dr. E.W. Steyerberg
- Telephone
- +31 71 526 9700
- e.w.steyerberg@lumc.nl
- ORCID iD
- 0000-0002-7787-0122
Ewout Steyerberg is professor of Clinical Biostatistics and Medical Decision Making at Leiden University Medical Center and Erasmus MC (Rotterdam, the Netherlands). He has been chairing the department of Biomedical Data Sciences since 2017. He was a Fellow of the Royal Netherlands Society for Arts and Sciences (KNAW). He spent sabbaticals at Duke University (Durham, NC: 1996) en Harvard University (Boston, MA: 2003 and 2005).
More information about Ewout Steyerberg
Ewout Steyerberg is professor of Clinical Biostatistics and Medical Decision Making at Leiden University Medical Center and Erasmus MC (Rotterdam, the Netherlands). He has been chairing the department of Biomedical Data Sciences since 2017. He was a Fellow of the Royal Netherlands Society for Arts and Sciences (KNAW). He spent sabbaticals at Duke University (Durham, NC: 1996) en Harvard University (Boston, MA: 2003 and 2005).
Biomedical Data Sciences
The department of Biomedical Data Sciences consists of 4 research sections. Advanced Data Management (ADM) is focused on high quality data acquisition and data management; Molecular Epidemiology is focused on unravelling biological mechanisms, including rheumatology and ageing; Medical Statistics is focused on the development and application of biostatistical methods; and Medical Decision Making is focused on the description and evaluation of medical decisions. Professor Steyerberg is primarily involved with the latter 2 sections (Medical Statistics and Medical Decision Making). His research concentrates on prediction. He has applied advanced regression analysis and related techniques in many clinical domains. Areas of interest include biostatistics, cost-effectiveness, and decision analysis. Contemporary research themes have his attention, including comparative effectiveness, Big Data, Artificial Intelligence (AI) and Machine Learning, Value-based Health Care, and Precision Medicine.
Professor Steyerberg’s methodological research concentrates on the role of prediction models and randomized clinical trials for better decision making in individual patients.
Academic career
1985-86: Medicine, Leiden University
1986-91: MSc, Biomedical Sciences, Leiden University (cum laude)
1996: PhD Erasmus University Rotterdam, “Prognostic modelling for clinical decision making” https://repub.eur.nl/pub/22495/
1996: sabbatical at Duke University, Durham, NC
2003 and 2005: sabbaticals at Dana Farber / Harvard Cancer Center, Boston, MA
2006: professor of Medical Decision Making, Erasmus MC, Rotterdam; inaugural address: https://repub.eur.nl/pub/13237/
2017: professor of Clinical Biostatistics and Medical Decision Making, LUMC, Leiden
Read E.Steyerberg's book here:
Clinical Prediction Models: A Practical Approach to Development, Validation, and Updating
Prizes and honourable appointments
Feb 1991 cum laude MSc Biomedical Sciences at Leiden University, The Netherlands
1995 Society for Medical Decision Making: student prize
1996 ‘TALENT stipendium’ from the Netherlands Organization for Scientific Research (‘NWO’) for a research at Duke University, Durham, NC
1999-2003 Fellowship from the Royal Netherlands Academy for Arts and Sciences
2005 Marx Research fellowship from Dana-Farber/ Harvard Cancer Center, Boston, MA
2016 John M. Eisenberg Award for Practical Application of Medical Decision Making Research by the Society for Medical Decision Making
2019 Member of the Royal Netherlands Academy for Arts and Sciences
2021 Member of the European Academy of Sciences and Arts
Professor Clinical Biostatistics and Medical Decision Making
- Faculteit Geneeskunde
- Divisie 4
- Biomedical Data Sciences
- Zian, A.; Overdevest, G.M.; Schutte, P.J.; Klok, F.A.; Steyerberg, E.W.; Moojen, W.A. & Gaag, N.A. van der (2024), Aspin: neurosurgical aspirin intervention prognostic study, Trials 25(1).
- Susanne Pinto, Dominika Šajbenová, Elisa Benincà, Sam Nooij, Elisabeth M Terveer, Josbert J Keller, Andrea E van der Meulen–de Jong, Johannes A Bogaards & Ewout W Steyerberg (2024), Dynamics of Gut Microbiota After Fecal Microbiota Transplantation in Ulcerative Colitis: Success Linked to Control of Prevotellaceae , Journal of Crohn's and Colitis.
- Butcher, S.C.; Essayagh, B.; Steyerberg, E.W.; Benfari, G.; Antoine, C.; Grigioni, F.; Tourneau, T. le; Roussel, J.C.; Wijngaarden, A. van; Marsan, N.A.; Tribouilloy, C.; Rusinaru, D.; Hochstadt, A.; Topilsky, Y.; Michelena, H.I.; Delgado, V.; Bax, J.J. & Enriquez-Sarano, M. (2023), Factors influencing post-surgical survival in degenerative mitral regurgitation, European Heart Journal 44(10).
- Rekkas, A.; Rijnbeek, P.R.; Kent, D.M.; Steyerberg, E.W. & Klaveren, D. van (2023), Estimating individualized treatment effects from randomized controlled trials, BMC Medical Research Methodology 23(1).
- Dang, R.H.; Dekkers, N.; Steyerberg, E.W.; Baldaque-Silva, F.; Omae, M.; Haasnoot, K.J.C.; Tilburg, L. van; Nobbenhuis, K.; Kraan, J. van der; Langers, A.M.J.; Hooft, J.E. van; Graaf, W. de; Koch, A.D.; Didden, P.; Moons, L.M.G.; Hardwick, J.C.H. & Boonstra, J.J. (2023), Predicting procedure duration of colorectal endoscopic submucosal dissection at Western endoscopy centers, Endoscopy International Open 11(08): E724-E732.
- Erp, I.A.M. van; Essen, T.A. van; Lingsma, H.; Pisica, D.; Singh, R.D.; Dijck, J.T.J.M. van; Volovici, V.; Kolias, A.; Peppel, L.D.; Heijenbrok-Kal, M.; Ribbers, G.M.; Menon, D.K.; Hutchinson, P.; Depreitere, B.; Steyerberg, E.W.; Maas, A.I.R.; Ruiter, G.C.W. de; Peul, W.C. & CENTER-TBI Investigators (2023), Early surgery versus conservative treatment in patients with traumatic intracerebral hematoma, Acta Neurochirurgica 165.
- Pastena, M. de; Bodegraven, E.A. van; Mungroop, T.H.; Vissers, F.L.; Jones, L.R.; Marchegiani, G.; Balduzzi, A.; Klompmaker, S.; Paiella, S.; Rad, S.T.; Koerkamp, B.G.; Eijck, C. van; Busch, O.R.; Hingh, I. de; Luyer, M.; Barnhill, C.; Seykora, T.; Maxwell, T.T.; Rooij, T. de; Tuveri, M.; Malleo, G.; Esposito, A.; Landoni, L.; Casetti, L.; Alseidi, A.; Salvia, R.; Steyerberg, E.W.; Abu Hilal, M.; Vollmer, C.M.; Besselink, M.G. & Bassi, C. (2023), Distal Pancreatectomy Fistula Risk Score (D-FRS) development and international validation, Annals of Surgery 277(5): E1099-E1105.
- Vermij, L.; Putter, H.; Jobsen, J.; Powell, M.; Boer, S. de; Leary, A.; Fyles, A.; Khaw, P.; Lutgens, L.; Jürgenliemk-Schulz, I.; Jong, M. de; Haverkort, D.; Nout, R.; Smit, V.; Steyerberg, E.; Bosse, T.; Creutzberg, C. & Horeweg, N. (2023), Development of an evidence-based adjuvant treatment decision support tool for endometrial cancer, Radiotherapy & Oncology 182: S484-S486.
- Thomassen, D.; Steyerberg, E. & Cessie, S. le (2023), A Bayesian (meta-)regression model for treatment effects on the risk difference scale, Statistics in Medicine 42(11).
- Rekkas, A.; Klaveren, D. van; Ryan, P.B.; Steyerberg, E.W.; Kent, D.M. & Rijnbeek, P.R. (2023), A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases, npj Digital Medicine 6(1).
- Roumans, C.A.M.; Bogt, R.D. van der; Nieboer, D.; Steyerberg, E.W.; Rizopoulos, D.; Lansdorp-Vogelaar, I.; Biermann, K.; Bruno, M.J.; Spaander, M.C.W. & ProBar Study Grp (2023), Clinical consequences of nonadherence to Barrett's esophagus surveillance recommendations, Diseases of the Esophagus 36(8).
- Villar, J.; González-Martin, J.M.; Añón, J.M.; Ferrando, C.; Soler, J.A.; Mosteiro, F.; Mora-Ordoñez, J.M.; Ambrós, A.; Fernández, L.; Montiel, R.; Vidal, A.; Muñoz, T.; Pérez-Méndez, L.; Rodríguez-Suárez, P.; Fernández, C.; Fernández, R.L.; Szakmany, T.; Burns, K.E.A.; Steyerberg, E.W. & Slutsky, A.S. (2023), Clinical relevance of timing of assessment of ICU mortality in patients with moderate-to-severe Acute Respiratory Distress Syndrome, Scientific Reports 13(1).
- Chalos, V.; Venema, E.; Mulder, M.J.H.L.; Roozenbeek, B.; Steyerberg, E.W.; Wermer, M.J.H.; Nijeholt, G.J.L.A.; Worp, H.B. van der; Goyal, M.; Campbell, B.C.V.; Muir, K.W.; Guillemin, F.; Bracard, S.; White, P.; Dávalos, A.; Jovin, T.G.; Hill, M.D.; Mitchell, P.J.; Demchuk, A.M.; Saver, J.L.; Lugt, A. van der; Brown, S.; Dippel, D.W.J.; Lingsma, H.F.; HERMES Collaborators & MR CLEAN Registry Investigators (2023), Development and validation of a postprocedural model to predict outcome after endovascular treatment for ischemic stroke, JAMA Neurology 80(9): 940-948.
- Essen, T.A. van; Erp, I.A.M. van; Lingsma, H.F.; Pisica, D.; Yue, J.K.; Singh, R.D.; Dijck, J.T.J.M. van; Volovici, V.; Younsi, A.; Kolias, A.; Peppel, L.D.; Heijenbrok-Kal, M.; Ribbers, G.M.; Menon, D.K.; Hutchinson, P.J.A.; Manley, G.T.; Depreitere, B.; Steyerberg, E.W.; Maas, A.I.R.; Ruiter, G.C.W. de; Peul, W.C. & CENTER-TBI Investigators (2023), Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI), EClinicalMedicine 63.
- Candel, B.G.J.; Nissen, S.K.; Nickel, C.H.; Raven, W.; Thijssen, W.; Gaakeer, M.I.; Lassen, A.T.; Brabrand, M.; Steyerberg, E.W.; Jonge, E. de & Groot, B. de (2023), Development and external validation of the International Early Warning Score for improved age- and sex-adjusted in-hospital mortality prediction in the emergency department, Critical Care Medicine 51(7): 881-891.
- Hond, A.A.H. de; Shah, V.B.; Kant, I.M.J.; Calster, B. van; Steyerberg, E.W. & Hernandez-Boussard, T. (2023), Perspectives on validation of clinical predictive algorithms, npj Digital Medicine 6(1).
- Dang, H.; Dekkers, N.; Steyerberg, E.W.; Baldaque-Silva, F.; Omae, M.; Haasnoot, K.J.C.; Tilburg, L. van; Nobbenhuis, K.; Kraan, J. van der; Langers, A.M.J.; Hooft, J.E. van; Graaf, W. de; Koch, A.D.; Didden, P.; Moons, L.M.G.; Hardwick, J.C.H. & Boonstra, J.J. (2023), Predicting procedure duration of colorectal endoscopic submucosal dissection at Western endoscopy centers (vol 11, pg E724, 2023), Endoscopy International Open 11(8): C5-C5.
- Yue, J.; Lee, Y.; Jain, S.; Sun, X.Y.; Essen, T. van; Pisica, D.; Belton, P.; Deng, H.; Satris, G.; Wong, J.; Kanter, J.; Tarapore, P.; Huang, M.; DiGiorgio, A.; Mukherjee, P.; Yuh, E.; Markowitz, A.; Steyerberg, E.; Lingsma, H.; Menon, D.; Maas, A. & Manley, G. (2023), PERFORMANCE OF THE IMPACT AND CRASH PROGNOSTIC MODELS FOR TRAUMATIC BRAIN INJURY IN A CONTEMPORARY MULTICENTER COHORT: A TRACKTBI STUDY, Journal of Neurotrauma 40(15-16): A33-A33.
- Azizpour, K.; Schutte, P.J.; Arts, M.P.; Pondaag, W.; Bouma, G.J.; Coppes, M.; Steyerberg, E.W.; Peul, W.C. & Vleggeert-Lankamp, C.L.A. (2023), Clinical outcome in decompression alone versus decompression and instrumented fusion in patients with isthmic spondylolisthesis, Journal of Neurosurgery: Spine 38(5): 573-584.
- Hond, A.A.H. de; Kant, I.M.J.; Fornasa, M.; Cina, G.; Elbers, P.W.G.; Thoral, P.J.; Arbous, M.S. & Steyerberg, E.W. (2023), Predicting readmission or death after discharge from the ICU, Critical Care Medicine 51(2): 291-300.
- Mikolic, A.; Steyerberg, E.W.; Polinder, S.; Wilson, L.; Zeldovich, M.; Steinbuechel, N. von; Newcombe, V.F.J.; Menon, D.K.; Naalt, J. van der; Lingsma, H.F.; Maas, A.I.R.; Klaveren, D. van & CENTER-TBI Participants (2023), Prognostic models for global functional outcome and post-concussion symptoms following mild traumatic brain injury, Journal of Neurotrauma 40(15-16): 1651-1670.
- Steinbuechel, N. von; Rauen, K.; Covic, A.; Krenz, U.; Bockhop, F.; Mueller, I.; Cunitz, K.; Polinder, S.; Steyerberg, E.W.; Vester, J.; Zeldovich, M. & CTR TBI participants investigator (2023), Sensitivity of outcome instruments in a priori selected patient groups after traumatic brain injury, PLoS ONE 18(4).
- Langenhuijsen, L.F.S.; Janse, R.J.; Venema, E.; Kent, D.M.; Diepen, M. van; Dekker, F.W.; Steyerberg, E.W. & Jong, Y. de (2023), Systematic metareview of prediction studies demonstrates stable trends in bias and low PROBAST inter-rater agreement, Journal of Clinical Epidemiology 159: 159-173.
- Calster, B. van; Steyerberg, E.W.; Wynants, L. & Smeden, M. van (2023), There is no such thing as a validated prediction model, BMC Medicine 21(1).
- Kaal, A.G.; Hoek, L. op de; Hochheimer, D.T.; Brouwers, C.; Wiersinga, W.J.; Snijders, D.; Rensing, K.L.; Dijk, C.E. van; Steyerberg, E.W. & Nieuwkoop, C. van (2023), Outcomes of community-acquired pneumonia using the Pneumonia Severity Index versus the CURB-65 in routine practice of emergency departments, ERJ Open Research 9(3).
- Wu, X.; Sun, Y.Y.; Xu, X.; Steyerberg, E.W.; Helmrich, I.R.A.R.; Lecky, F.; Guo, J.Y.; Li, X.; Feng, J.F.; Mao, Q.; Xie, G.T.; Maas, A.I.R.; Gao, G.Y.; Jiang, J.Y. & CTR-TBI Participants Investigator (2023), Mortality prediction in severe traumatic brain injury using traditional and machine learning algorithms, Journal of Neurotrauma 40(13-14): 1366-1375.
- Bhattacharyay, S.; Caruso, P.F.; Åkerlund, C.; Wilson, L.; Stevens, R.D.; Menon, D.K.; Steyerberg, E.W.; Nelson, D.W.; Ercole, A. & CENTER TBI Investigators Participants (2023), Mining the contribution of intensive care clinical course to outcome after traumatic brain injury, npj Digital Medicine 6(1).
- Hudda, M.T.; Archer, L.; Smeden, M. van; Moons, K.G.M.; Collins, G.S.; Steyerberg, E.W.; Wahlich, C.; Reitsma, J.B.; Riley, R.D.; Calster, B. van & Wynants, L. (2023), Minimal reporting improvement after peer review in reports of COVID-19 prediction models: systematic review, Journal of Clinical Epidemiology 154: 75-84.
- Kaplan, Z.L.R.; Vlegel, M. van der; Dijck, J.T.J.M. van; Pisica, D.; Leeuwen, N. van; Lingsma, H.F.; Steyerberg, E.W.; Haagsma, J.A.; Majdan, M.; Polinder, S. & CENTER TBI Participants Invest (2023), Intramural healthcare consumption and costs after traumatic brain injury, Journal of Neurotrauma 40(19-20).
- Meijden, S.L. van der; Hond, A.A.H. de; Thoral, P.J.; Steyerberg, E.W.; Kant, I.M.J.; Cinà, G. & Arbous, M.S. (2023), Intensive care unit physicians' perspectives on artificial intelligence-based clinical decision support tools, JMIR Human Factors 10.
- Steinbuechel, N. von; Hahm, S.; Muehlan, H.; Arango-Lasprilla, J.C.; Bockhop, F.; Covic, A.; Schmidt, S.; Steyerberg, E.W.; Maas, A.I.R.; Menon, D.; Andelic, N.; Zeldovich, M. & CTR TBI Participants Investigators (2023), Impact of sociodemographic, premorbid, and injury-related factors on patient-reported outcome trajectories after traumatic brain injury (TBI), Journal of Clinical Medicine 12(6).
- Binuya, M.A.E.; Engelhardt, E.G.; Schats, W.; Schmidt, M.K. & Steyerberg, E.W. (2022), Methodological guidance for the evaluation and updating of clinical prediction models: a systematic review, BMC Medical Research Methodology 22(1).
- Gravesteijn, B.Y.; Steyerberg, E.W. & Lingsma, H.F. (2022), Modern learning from big data in critical care, Neurocritical Care 37: 174-184.
- McLernon, D.J.; Giardiello, D.; Calster, B. van; Wynants, L.; Geloven, N. van; Smeden, M. van; Therneau, T.; Steyerberg, E.W. & STRATOS Initiative (2022), Assessing performance and clinical usefulness in prediction models with survival outcomes, Annals of Internal Medicine.
- Meulenbroek, A.L.; Faes, M.C.; Mil, S.R. van; Buimer, M.G.; Groot, H.G.W. de; Veen, E.J.; Ho, G.H.; Boonman-de Winter, L.J.; Vries, J. de; Gorkom, R. van; Toonders, F.; Alphen, R. van; Overveld, K. van; Verbogt, N.; Steyerberg, E.W. & Laan, L. van der (2022), Multicomponent prehabilitation as a novel strategy for preventing delirium in older chronic limb threatening ischemia patients, Clinical Interventions in Aging 17: 767-776.
- Maas, A.I.R.; Ercole, A.; Keyser, V. de; Menon, D.K. & Steyerberg, E.W. (2022), Opportunities and challenges in high-quality contemporary data collection in traumatic brain injury, Neurocritical Care 37(SUPPL 2): 192-201.
- Dregmans, E.; Kaal, A.G.; Meziyerh, S.; Kolfschoten, N.E.; Aken, M.O. van; Schippers, E.F.; Steyerberg, E.W. & Nieuwkoop, C. van (2022), Analysis of variation between diagnosis at admission vs discharge and clinical outcomes among adults with possible bacteremia, Jama Network Open 5(6).
- Huijben, J.A.; Pisica, D.; Ceyisakar, I.; Stocchetti, N.; Citerio, G.; Maas, A.I.R.; Steyerberg, E.W.; Menon, D.K.; Jagt, M. van der; Lingsma, H.F. & ICU Stratum (2022), Pharmaceutical venous thrombosis prophylaxis in critically ill traumatic brain injury patients, Neurotrauma Reports 3(1): 4-14.
- Giardiello, D.; Hooning, M.J.; Hauptmann, M.; Keeman, R.; Heemskerk-Gerritsen, B.A.M.; Becher, H.; Blomqvist, C.; Bojesen, S.E.; Bolla, M.K.; Camp, N.J.; Czene, K.; Devilee, P.; Eccles, D.M.; Fasching, P.A.; Figueroa, J.D.; Flyger, H.; Garcia-Closas, M.; Haiman, C.A.; Hamann, U.; Hopper, J.L.; Jakubowska, A.; Leeuwen, F.E.; Lindblom, A.; Lubinski, J.; Margolin, S.; Martinez, M.E.; Nevanlinna, H.; Nevelsteen, I.; Pelders, S.; Pharoah, P.D.P.; Siesling, S.; Southey, M.C.; Hout, A.H. van der; Hest, L.P. van; Chang-Claude, J.; Hall, P.; Easton, D.F.; Steyerberg, E.W. & Schmidt, M.K. (2022), PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in similar to 200,000 patients, Breast Cancer Research 24(1).
- Buisman, F.E.; Giardiello, D.; Kemeny, N.E.; Steyerberg, E.W.; Hoppener, D.J.; Galjart, B.; Nierop, P.M.H.; Balachandran, V.P.; Cercek, A.; Drebin, J.A.; Gonen, M.; Jarnagin, W.R.; Kingham, T.P.; Vermeulen, P.B.; Wei, A.C.; Grunhagen, D.J.; Verhoef, C.; D'Angelica, M.I. & Koerkamp, B.G. (2022), Predicting 10-year survival after resection of colorectal liver metastases, European Journal of Cancer 168: 25-33.
- Heinze, G.; Smeden, M. van; Wynants, L.; Steyerberg, E. & Calster, B. van (2022), Prediction models: stepwise development and simultaneous validation is a step back.
- Saffari, S.E.; Volovici, V.; Ong, M.E.H.; Goldstein, B.A.; Vaughan, R.; Dammers, R.; Steyerberg, E.W. & Liu, N. (2022), Proper use of multiple imputation and dealing with missing covariate data, World Neurosurgery 161: 284-290.
- Geloven, N. van; Giardiello, D.; Bonneville, E.F.; Teece, L.; Ramspek, C.L.; Smeden, M. van; Snell, K.I.E.; Calster, B. van; Pohar-Perme, M.; Riley, R.D.; Putter, H. & Steyerberg, E. (2022), Validation of prediction models in the presence of competing risks, BRITISH MEDICAL JOURNAL.
- Singh, R.D.; Dijck, J.T.J.M. van; Essen, T.A. van; Lingsma, H.F.; Polinder, S.S.; Kompanje, E.J.O.; Zwet, E.W. van; Steyerberg, E.W.; Ruiter, G.C.W. de; Depreitere, B. & Peul, W.C. (2022), Randomized evaluation of surgery in elderly with traumatic acute SubDural hematoma (RESET-ASDH trial), Trials 23(1).
- Whitehouse, D.P.; Monteiro, M.; Czeiter, E.; Vande Vyvere, T.; Valerio, F.; Ye, Z.; Amrein, K.; Kamnitsas, K.; Xu, H.Y.; Yang, Z.H.; Verheyden, J.; , T. das; Kornaropoulos, E.N.; Steyerberg, E.; Maas, A.I.R.; Wang, K.K.W.; Buki, A.; Glocker, B.; Menon, D.K.; Newcombe, V.F.J. & CENTER-TBI Participants Investigat (2022), Relationship of admission blood proteomic biomarkers levels to lesion type and lesion burden in traumatic brain injury, EBioMedicine 75.
- Villar, J.; Fernandez, C.; Gonzalez-Martin, J.M.; Ferrando, C.; Anon, J.M.; Saz-Ortiz, A.M. del; Diaz-Lamas, A.; Bueno-Gonzalez, A.; Fernandez, L.; Dominguez-Berrot, A.M.; Peinado, E.; Andaluz-Ojeda, D.; Gonzalez-Higueras, E.; Vidal, A.; Fernandez, M.M.; Mora-Ordonez, J.M.; Murcia, I.; Tarancon, C.; Merayo, E.; Perez, A.; Romera, M.A.; Alba, F.; Pestana, D.; Rodriguez-Suarez, P.; Fernandez, R.L.; Steyerberg, E.W.; Berra, L.; Slutsky, A.S. & Spanish Initiative Epidemiology St (2022), Respiratory Subsets in Patients with Moderate to Severe Acute Respiratory Distress Syndrome for Early Prediction of Death, Journal of Clinical Medicine 11(19).
- Marincowitz, C.; Gravesteijn, B.; Sheldon, T.; Steyerberg, E. & Lecky, F. (2022), Response to performance of the Hull Salford Cambridge Decision Rule: the start of the traumatic brain injury (TBI) assessment and recovery journey.
- Caudri, D.; Turkovic, L.; Klerk, N.H. de; Rosenow, T.; Murray, C.P.; Steyerberg, E.W.; Ranganathan, S.C.; Sly, P.; Stick, S.M.; Breuer, O. & AREST CF Study Grp (2022), A screening tool to identify risk for bronchiectasis progression in children with cystic fibrosis, Pediatric Pulmonology 57(1): 122-131.
- Wallisch, C.; Bach, P.; Hafermann, L.; Klein, N.; Sauerbrei, W.; Steyerberg, E.W.; Heinze, G.; Rauch, G. & Topic Grp 2 STRATOS Initiative (2022), Review of guidance papers on regression modeling in statistical series of medical journals, PLoS ONE 17(1).
- Akdeniz, D.; Kramer, I.; Deurzen, C.H.M. van; Heemskerk-Gerritsen, B.A.M.; Schaapveld, M.; Westenend, P.J.; Voogd, A.C.; Jager, A.; Steyerberg, E.W.; Sleijfer, S.; Schmidt, M.K. & Hooning, M.J. (2022), Risk of metachronous contralateral breast cancer in patients with primary invasive lobular breast cancer, Cancer Medicine 12(3).
- Williams, R.D.; Markus, A.F.; Yang, C.; Duarte-Salles, T.; DuVall, S.L.; Falconer, T.; Jonnagaddala, J.; Kim, C.; Rho, Y.; Williams, A.E.; Machado, A.A.; An, M.H.; Aragon, M.; Areia, C.; Burn, E.; Choi, Y.H.; Drakos, I.; Abrahao, M.T.F.; Fernandez-Bertolin, S.; Hripcsak, G.; Kaas-Hansen, B.S.; Kandukuri, P.L.; Kors, J.A.; Kostka, K.; Liaw, S.T.; Lynch, K.E.; Machnicki, G.; Matheny, M.E.; Morales, D.; Nyberg, F.; Park, R.W.; Prats-Uribe, A.; Pratt, N.; Rao, G.; Reich, C.G.; Rivera, M.; Seinen, T.; Shoaibi, A.; Spotnitz, M.E.; Steyerberg, E.W.; Suchard, M.A.; You, S.C.; Zhang, L.; Zhou, L.L.; Ryan, P.B.; Prieto-Alhambra, D.; Reps, J.M. & Rijnbeek, P.R. (2022), Seek COVER, BMC Medical Research Methodology 22(1).
- Richter, S.; Winzeck, S.; Czeiter, E.; Amrein, K.; Kornaropoulos, E.N.; Verheyden, J.; Sugar, G.; Yang, Z.H.; Wang, K.V.; Maas, A.I.R.; Steyerberg, E.; Buki, A.; Newcombe, V.F.J.; Menon, D.K. & Collaborative European NeuroTrauma (2022), Serum biomarkers identify critically ill traumatic brain injury patients for MRI, Critical Care 26(1).
- Thomas, I.; Dickens, A.M.; Posti, J.P.; Czeiter, E.; Duberg, D.; Sinioja, T.; Krakstrom, M.; Helmrich, I.R.A.R.; Wang, K.K.W.; Maas, A.I.R.; Steyerberg, E.W.; Menon, D.K.; Tenovuo, O.; Hyotylainen, T.; Buki, A.; Oresic, M. & CENTER-TBI Participants Investigat (2022), Serum metabolome associated with severity of acute traumatic brain injury, Nature Communications 13(1).
- Roumans, C.A.M.; Zellenrath, P.A.; Steyerberg, E.W.; Lansdorp-Vogelaar, I.; Doukas, M.; Biermann, K.; Alderliesten, J.; Ingen, G. van; Nagengast, W.B.; Karrenbeld, A.; Borg, F. ter; Hage, M.; Borg, P.C.J. ter; Bakker, M.A. den; Alkhalaf, A.; Moll, F.C.P.; Brouwer-Hol, L.; Baarlen, J. van; Quispel, R.; Tilburg, A. van; Burger, J.P.W.; Tilburg, A.J.P. van; Ooms, A.H.A.G.; Tang, T.J.; Romberg-Camps, M.J.L.; Goudkade, D.; Bruno, M.J.; Rizopoulos, D. & Spaander, M.C.W. (2022), Sex differences in neoplastic progression in Barrett's esophagus, Cancers 14(13).
- Tomer, A.; Nieboer, D.; Roobol, M.J.; Steyerberg, E.W. & Rizopoulos, D. (2022), Shared decision making of burdensome surveillance tests using personalized schedules and their burden and benefit, Statistics in Medicine 41(12): 2115-2131.
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- Akdeniz D., Kramer I., Van Deurzen C. H. M., Schaapveld M., Westenend P. J., Voogd A. C., Jager A., Steyerberg E. W., Sleijfer S., Schmidt M. K. & Hooning M. J. (2018), Higher risk of metachronous contralateral breast cancer in patients with invasive lobular breast cancer, European Journal of Cancer 92: S46-S46.
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- Widschwendter, M.; Jones, A.; Evans, I.; Reiser, D.; Dillner, J.; Sundstrom, K.; Steyerberg, E.W.; Vergouwe, Y.; Wegwarth, O.; Rebitschek, F.G.; Siebert, U.; Sroczynski, G.; Beaufort, I.D. de; Bolt, I.; Cibula, D.; Zikan, M.; Bjorge, L.; Colombo, N.; Harbeck, N.; Dudbridge, F.; Tasse, A.M.; Knoppers, B.M.; Joly, Y.; Teschendorff, A.E.; Pashayan, N. & FORECEE 4C Consortium (2018), Epigenome-based cancer risk prediction: rationale, opportunities and challenges, Nature Reviews Clinical Oncology 15(5): 292-309.
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- Gravesteijn Benjamin Y., Sewalt Charlie A., Steyerberg Ewout W., Maas Andrew, Lingsma Hester F. & Klimek Markus (2018), PRACTICE VARIATION OF INTUBATION IN TRAUMATIC BRAIN INJURY IN EUROPE, Journal of Neurotrauma 35(16): A108-A109.
- Tran, A.; Matar, M.; Lampron, J.; Steyerberg, E.; Taljaard, M. & Vaillancourt, C. (2018), Early identification of patients requiring massive transfusion, embolization or hemostatic surgery for traumatic hemorrhage: A systematic review and meta-analysis, Journal of Trauma and Acute Care Surgery 84(3): 505-516.
- Volovici, V.; Huijben, J.A.; Ercole, A.; Stocchetti, N.; Dirven, C.M.F.; Jagt, M. van der; Steyerberg, E.W.; Lingsma, H.F.; Menon, D.K.; Maas, A.I.R. & Haitsma, I.K. (2018), Ventricular Drainage Catheters versus Intracranial Parenchymal Catheters for Intracranial Pressure Monitoring-Based Management of Traumatic Brain Injury: A Systematic Review and Meta-Analysis, Journal of Neurotrauma.
- Van Essen Thomas A., Den Boogert Hugo F., Cnossen Maryse C., De Ruiter Godard C. W., Haitsma Iain, Polinder Suzanne, Steyerberg Ewout W., Menon David K., Maas Andrew I. R., Lingsma Hester F. & Peul Wilco C. (2018), VARIATION IN NEUROSURGICAL MANAGEMENT OF TRAUMATIC BRAIN INJURY: A SURVEY IN 68 CENTERS PARTICIPATING IN THE CENTER-TBI STUDY, Journal of Neurotrauma 35(16): A184-A185.
- Essen, T.A. van; Dijkman, M.D.; Cnossen, M.C.; Moudrous, W.; Ardon, H.; Schoonman, G.G.; Steyerberg, E.W.; Peul, W.C.; Lingsma, H.F. & Ruiter, G.C.W. de (2018), Comparative Effectiveness of Surgery for Traumatic Acute Subdural Hematoma in an Aging Population, Journal of Neurotrauma.
- Steyerberg, E.W. (2018), Validation in prediction research: the waste by data splitting COMMENTARY, Journal of Clinical Epidemiology 103: 131-133.
- Fusar-Poli, P.; Hijazi, Z.; Stahl, D. & Steyerberg, E.W. (2018), The Science of Prognosis in Psychiatry A Review, JAMA Psychiatry 75(12): 1289-1297.
- Ridder, I.R. de; Dijkland, S.A.; Scheele, M.; Hertog, H.M. den; Dirks, M.; Westendorp, W.F.; Nederkoorn, P.J.; Beek, D. van de; Ribbers, G.M.; Steyerberg, E.W.; Lingsma, H.F. & Dippel, D.W.J. (2018), Development and validation of the Dutch Stroke Score for predicting disability and functional outcome after ischemic stroke: A tool to support efficient discharge planning, European Stroke Journal 3(2): 165-173.
- Van Essen Thomas A., Peppel Lianne, Van Dijck Jeroen, Dijkman Mark, Lingsma Hester F., Heijenbrok-Kal Majanka, De Ruiter Godard, Steyerberg Ewout W., Ribbers Gerard & Peul Wilco C. (2018), THE NET-QURE STUDY: AN OBSERVATIONAL COHORT STUDY ON NEUROSURGICAL AND REHABILITATION STRATEGIES FOR TRAUMATIC BRAIN INJURY, Journal of Neurotrauma 35(16): A213-A213.
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- Walgaard, C.; Jacobs, B.C.; Lingsma, H.F.; Steyerberg, E.W.; Cornblath, D.R.; Doorn, P.A. van & Dutch GBS Study Grp (2018), Second IVIg course in Guillain-Barre syndrome patients with poor prognosis (SID-GBS trial): Protocol for a double-blind randomized, placebo-controlled clinical trial, Journal of the Peripheral Nervous System 23(4): 210-215.
- Gelder, J. de; Lucke, J.A.; Blomaard, L.C.; Booijen, A.M.; Fogteloo, A.J.; Anten, S.; Steyerberg, E.W.; Alsma, J.; Schuit, S.C.E.K.N.; Brink, A.; Groot, B. de; Blauw, G.J. & Mooijaart, S.P. (2018), Optimization of the APOP screener to predict functional decline or mortality in older emergency department patients: Cross-validation in four prospective cohorts, Experimental Gerontology 110: 253-259.
- Calster, B. van; Steyerberg, E.W.; Collins, G.S. & Smits, T. (2018), Consequences of relying on statistical significance: Some illustrations, European Journal of Clinical Investigation 48(5).
- Zachariasse, J.M.; Nieboer, D.; Oostenbrink, R.; Moll, H.A. & Steyerberg, E.W. (2018), Multiple performance measures are needed to evaluate triage systems in the emergency department, Journal of Clinical Epidemiology 94: 27-34.
- Engelhardt, E.G.; Revesz, D.; Tamminga, H.J.; Punt, C.J.A.; Koopman, M.; Onwuteaka-Philipsen, B.D.; Steyerberg, E.W.; Vet, H.C.W. de & Coupe, V.M.H. (2018), Inventory of oncologists' unmet needs for tools to support decision-making about palliative treatment for metastatic colorectal cancer, BMC Medical Informatics and Decision Making 18.
- Hofstede, S.N.; Bodegom-Vos, L. van; Kringos, D.S.; Steyerberg, E. & Marang-van de Mheen, P.J. (2018), Mortality, readmission and length of stay have different relationships using hospital-level versus patient-level data: an example of the ecological fallacy affecting hospital performance indicators, BMJ Quality and Safety 27(6): 474-483.
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- Nieboer, D.; Tomer, A.; Rizopoulos, D.; Roobol, M.J. & Steyerberg, E.W. (2018), Active surveillance: a review of risk-based, dynamic monitoring, Translational Andrology and Urology 7(1): 106-115.
- Huijben, J.A.; Jagt, M. van der; Cnossen, M.C.; Kruip, M.J.H.A.; Haitsma, I.K.; Stocchetti, N.; Maas, A.I.R.; Menon, D.K.; Ercole, A.; Maegele, M.; Stanworth, S.J.; Citerio, G.; Polinder, S.; Steyerberg, E.W.; Lingsma, H.F. & CTR-TBI Investigators & Particip (2018), Variation in Blood Transfusion and Coagulation Management in Traumatic Brain Injury at the Intensive Care Unit: A Survey in 66 Neurotrauma Centers Participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study, Journal of Neurotrauma 35(2): 323-332.
- Jaja, B.N.R.; Saposnik, G.; Lingsma, H.F.; Macdonald, E.; Thorpe, K.E.; Mamdani, M.; Steyerberg, E.W.; Molyneux, A.; Manoel, A.L.D.; Schatlo, B.; Hanggi, D.; Hasan, D.; Wong, G.K.C.; Etminan, N.; Fukuda, H.; Torner, J.; Schaller, K.L.; Suarez, J.I.; Stienen, M.N.; Vergouwen, M.D.I.; Rinkel, G.J.E.; Spears, J.; Cusimano, M.D.; Todd, M.; Roux, P. le; Kirkpatrick, P.; Pickard, J.; Bergh, W.M. van den; Murray, G.; Johnston, S.C.; Yamagata, S.; Mayer, S.; Schweizer, T.A.; Macdonald, R.L. & SAHIT Collaboration (2018), Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study, British Medical Journal 360.
- Venema, E.; Mulder, M.J.H.L.; Roozenbeek, B.; Broderick, J.P.; Yeatts, S.D.; Khatri, P.; Berkhemer, O.A.; Emmer, B.J.; Roos, Y.B.W.E.M.; Majoie, C.B.L.M.; Oostenbrugge, R.J. van; Zwam, W.H. van; Lugt, A. van der; Steyerberg, E.W.; Dippel, D.W.J. & Lingsma, H.F. (2017), Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials, BMJ 357.
- Shapiro, J.; Biermann, K.; Klaveren, D. van; Offerhaus, G.J.A.; Kate, F.J.W. ten; Meijer, S.L.; Henegouwen, M.I.V.; Steyerberg, E.W.; Wijnhoven, B.P.L. & Lanschot, J.J.B. van (2017), Prognostic Value of Pretreatment Pathological Tumor Extent in Patients Treated With Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal or Junctional Cancer, Annals of Surgery 265(2): 356-362.
- Bosch, T.P.P. van den; Hilbrands, L.B.; Kraaijeveld, R.; Litjens, N.H.R.; Rezaee, F.; Nieboer, D.; Steyerberg, E.W.; Gestel, J.A. van; Roelen, D.L.; Clahsen-van Groningen, M.C.; Baan, C.C. & Rowshani, A.T. (2017), Pretransplant Numbers of CD16(+) Monocytes as a Novel Biomarker to Predict Acute Rejection After Kidney Transplantation: A Pilot Study, American Journal of Transplantation 17(10): 2659-2667.
- Stalenhoef, J.E.; Starre, W.E. van der; Vollaard, A.M.; Steyerberg, E.W.; Delfos, N.M.; Leyten, E.M.S.; Koster, T.; Ablij, H.C.; van't Wout, J.W.; Dissel, J.T. van & Nieuwkoop, C. van (2017), Hospitalization for community-acquired febrile urinary tract infection: validation and impact assessment of a clinical prediction rule, BMC Infectious Diseases 17.
- Eekelen, R. van; Geloven, N. van; Wely, M. van; McLernon, D.J.; Eijkemans, M.J.; Repping, S.; Steyerberg, E.W.; Mol, B.W.; Bhattacharya, S. & Veen, F. van der (2017), Constructing the crystal ball: how to get reliable prognostic information for the management of subfertile couples, Human Reproduction 32(11): 2153-2158.
- McLernon, D.; Velde, E. te; Steyerberg, E.; Lee, A.; Mol, B. & Bhattacharya, S. (2017), A dynamic approach to estimating the chances of a live birth in couples with unexplained subfertility with and without treatment: a population-based record-linkage study, Human Reproduction 32: 324-324.
- Sotomi, Y.; Onuma, Y.; Cavalcante, R.; Ahn, J.M.; Lee, C.W.; Klaveren, D. van; Winter, R.J. de; Wykrzykowska, J.J.; Farooq, V.; Morice, M.C.; Steyerberg, E.W.; Park, S.J. & Serruys, P.W. (2017), Geographical Difference of the Interaction of Sex With Treatment Strategy in Patients With Multivessel Disease and Left Main Disease: A Meta-Analysis From SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery), PRECOMBAT (Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease), and BEST (Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease) Randomized Controlled Trials, Circulation: Cardiovascular Interventions 10(5).
- Jairam, A.P.; Timmermans, L.; Eker, H.H.; Pierik, R.E.G.J.M.; Klaveren, D. van; Steyerberg, E.W.; Timman, R.; Ham, A.C. van der; Dawson, I.; Charbon, J.A.; Schuhmacher, C.; Mihaljevic, A.; Izbicki, J.R.; Fikatas, P.; Knebel, P.; Fortelny, R.H.; Kleinrensink, G.J.; Lange, J.F.; Jeekel, H.J. & PRIMA Trialist Grp (2017), Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial, Lancet 390(10094): 567-576.
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- Maas, A.I.R.; Menon, D.K.; Adelson, P.D.; Andelic, N.; Bell, M.J.; Belli, A.; Bragge, P.; Brazinova, A.; Burki, A.; Chesnut, R.M.; Citerio, G.; Coburn, M.; Cooper, D.J.; Crowder, A.T.; Czeiter, E.; Czosnyka, M.; Diaz-Arrastia, R.; Dreier, J.P.; Duhaime, A.C.; Ercole, A.; Essen, T.A. van; Feigin, V.L.; Gao, G.Y.; Giacino, J.; Gonzalez-Lara, L.E.; Gruen, R.L.; Gupta, D.; Hartings, J.A.; Hill, S.; Jiang, J.Y.; Ketharanathan, N.; Kompanje, E.J.O.; Lanyon, L.; Laureys, S.; Lecky, F.; Levin, H.; Lingsma, H.F.; Maegele, M.; Majdan, M.; Manley, G.; Marsteller, J.; Mascia, L.; McFadyen, C.; Mondello, S.; Newcombe, V.; Palotie, A.; Parizel, P.M.; Peul, W.; Piercy, J.; Polinder, S.; Puybasset, L.; Rasmussen, T.E.; Rossaint, R.; Smielewski, P.; Soderberg, J.; Stanworth, S.J.; Stein, M.B.; Steinbuchel, N. von; Stewart, W.; Steyerberg, E.W.; Stocchetti, N.; Synnot, A.; Ao, B.T.; Tenovuo, O.; Theadom, A.; Tibboel, D.; Videtta, W.; Wang, K.K.W.; Williams, W.H.; Wilson, L.; Yaffe, K. & InTBIR Participants Investigators (2017), Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research, Lancet Neurology 16(12): 987-1048.
- Smedinga, H.; Steyerberg, E.W.; Beukers, W.; Klaveren, D. van; Zwarthoff, E.C. & Vergouwe, Y. (2017), Prediction of Multiple Recurrent Events: A Comparison of Extended Cox Models in Bladder Cancer, American Journal of Epidemiology 186(5): 612-623.
- Cnossen, M.C.; Huijben, J.A.; Jagt, M. van der; Volovici, V.; Essen, T. van; Polinder, S.; Nelson, D.; Ercole, A.; Stocchetti, N.; Citerio, G.; Peul, W.C.; Maas, A.I.R.; Menon, D.; Steyerberg, E.W.; Lingsma, H.F. & CENTER-TBI Investigators (2017), Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study, Critical Care 21.
- Mulder, M.J.H.L.; Venema, E.; Roozenbeek, B.; Broderick, J.P.; Yeatts, S.D.; Khatri, P.; Berkhemer, O.A.; Roos, Y.B.W.E.M.; Majoie, C.B.L.M.; Oostenbrugge, R.J. van; Zwam, W.H. van; Lugt, A. van der; Steyerberg, E.W.; Dippel, D.W.J. & Lingsma, H.F. (2017), Towards personalised intra- arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid, BMJ Open 7(3).
- Klaveren, D. van; Wong, J.B.; Kent, D.M. & Steyerberg, E.W. (2017), Biases in Individualized Cost-effectiveness Analysis: Influence of Choices in Modeling Short-Term, Trial-Based, Mortality Risk Reduction and Post-Trial Life Expectancy, Medical Decision Making 37(7): 770-778.
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