Edo de Kloet
Professor / guest
- Name
- Prof.dr. E.R. de Kloet
- Telephone
- +31 71 527 2727
- e.kloet@lacdr.leidenuniv.nl
Hormones are crucial for health and disease. In our research we focus on the action of hormones released after stress. These stress hormones program in early life brain circuits that underly emotion and cognition, they protect the brain and regulate the ageing process. Stress hormones determine vulnerability and resilience to depression and schizophrenia depending on genetic predisposition, and are of importance for the onset and progression of neurodegenerative processes. To understand how this enormous diversity in action of stress hormones occurs a unique integrated experimental approach from gene to behaviour is used.
The title of his inaugural lecture was 'Evenwicht in een veranderende wereld'.
De Kloet ER, Joëls M, Holsboer F (2005) Stress and the brain: from adaptation to disease. Nature Rev Neurosci. 6: 463-475.
Contact
Contact
Contact
Professor / guest
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Algemeen
- Kloet E.R. de (5 March 2010), Tussenbalans. Rede uitgesproken Ter gelegenheid van zijn afscheid als hoogleraar in de Medische Farmacologie aan de Universiteit Leiden. Leiden. [lecture].
- Kloet E.R. de (5 March 2010), Tussenbalans. Address given On the occasion of his retirement as head of department and professor of Medical Pharmacology at Leiden University. Leiden. [lecture].
- Kloet E.R. de (2000), Neuropendocriene aspecten van stress: een preklinische visie. Symposium: De invloed van stress op het brein. Groningen. [lecture].
- Kloet E.R. de (2000), Stress, apolipoprotein E and Alzheimer's Disease. Voordracht. Buenos Aires. [lecture].
- Kloet E.R. de (2000), Stress and serotonin: implications for development of novel anti-depressants. Lezing Yamanouchi. Leiderdorp. [lecture].
- Kloet E.R. de (2000), Fron Glucose to Glucocorticoids. 30th Anniversary of the Society for Experimental and Clinical Neurochemistry. Beerse. [lecture].
- Kloet E.R. de (2000), Stress in the Brain. Zentral Institut fuer Moleculaire Neurobiologie. Hamburg. [lecture].
- Kloet E.R. de (1998), Glucocorticoids, stress and aging: effect of early life eperience. Colloquium Stress en veroudering, Nederlandse Vereniging voor Gerontologie. Utrecht, NL. [lecture].
- Kloet E.R. de (1998), Neuroendocrinology of stress: focus on feedback. 1998 European medal lecture, 189th meeting of the British Society for Endocrinology.. London, UK. [lecture].
- Kloet E.R. de (1998), Brain corticosteroid receptor balance and homeostatic control: implications for disease. Festvortrag des Emil Kraepelin professors 1998, Max Planck Institute for Psychiatrie.. Munich, Germany. [lecture].
- Kloet E.R. de (1998), Functional implications of brain cortocosteroid receptor diversity. Department of Neurology. Univ. of Umea, Sweden. [lecture].
- Kloet E.R. de (1998), Neuroendocrinology of stress: implications for neuropharmaceutical intervention. Baker Institute. Melbourne, Australia. [lecture].
- Kloet E.R. de (1998), Corticosteroid receptor imbalance and stress-related disorders: cause or effect?. Institute of Biology and Experimental Medicine. Buenos Aires, Argentina. [lecture].
- Kloet E.R. de (1998), Steroiden bij stress en veroudering. AIO-cursus Endocrinologie, Onderzoekschool Denovem. Utrecht, NL. [lecture].
- Kloet E.R. de (1998), Adrenal steroids and cognitive functions and mental well being in the elderly. Satellite Symposium Forum European Neuroscience Steroid action in the aging brain.. Berlin, Germany. [lecture].
- Kloet E.R. de (1998), Corticosteroid modulation of cognitive function. Symposium Molecular basis of behaviour. Volkswagen Stiftung, Berlin, Germany. [lecture].
- Kloet E.R. de (1998), Corticosteroid dysregulation and depression: cause or effect?. XXIXth Congress International Society of Psychoneuroendocrinology.. Trier, Germany. [lecture].
- Kloet E.R. de (1998), Brain corticosteroid receptor balance and homeostatic control: implications for disease. Festvortrag des Emil Kraepelin professors 1998, Max Planck Institute for Psychiatrie.. Munich, Germany. [lecture].
- Kloet E.R. de (1998), Brain corticosteroid receptors and depression. Symposium Steroids, Stress and Depression XXI C1NP Congress.. Glasgow, UK. [lecture].
- Kloet E.R. de (1998), Adrenal steroids and cognitive functions and mental well being in the elderly. Satellite Symposium Forum European Neuroscience Steroid action in the aging brain.. Berlin, Germany. [lecture].
- Kloet E.R. de (1998), Modulation of brain corticosteroid receptor function. Symposium Steroids in the Brain, 4th European Congress of Endocrinology.. Sevilla, Spain. [lecture].
- Kloet E.R. de (1998), Brain corticosteroid receptors and neural stress circuitry. Symposium Glucocorticoid feedback in brain stress circuitry: novel methods, novel insights, Second World Congress on Stress. Melbourne, Australia. [lecture].