Cas van der Horst
Research technician
- Name
- C. van der Horst MSc
- Telephone
- +31 71 527 4607
- c.van.der.horst@lacdr.leidenuniv.nl
- ORCID iD
- 0000-0002-5859-5348
![](/binaries/content/gallery/ul2/portraits/science/h/cas-van-der-horst---lacdr.jpg/cas-van-der-horst---lacdr.jpg/d200x250)
Research technician
- Science
- Leiden Academic Centre for Drug Research
- LACDR/Medicinal Chemistry
- Hollander L.S. den, Beerkens B.L.H., Dekkers S., Veldhoven J.P.D. van, Ortiz Zacarías N.V., Horst C. van der, Sieders E.G., Valk B. de, Wang J., IJzerman A.P., Es D. van der & Heitman L.H. (2024), Labeling of CC chemokine receptor 2 with a versatile intracellular allosteric probe, ACS Chemical Biology 19(9): 2070-2080.
- Bouma, J., Broekhuis J.D., Horst C. van der, Kumar P., Ligresti A., Stelt M. van der & Heitman L.H. (2023), Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor, Biochemical Pharmacology 218: 115924.
- Li X., Chang H., Bouma J., Paus L.V. de, Mukhopadhyay P., Paloczi J., Mustafa M., Horst C. van der, Kumar S.S., Wu L., Yu Y., Berg R.J.B.H.N. van den, Janssen A.P.A., Lichtman A., Liu Z.J., Pacher P., Stelt M. van der, Heitman L.H. & Hua T. (2023), Structural basis of selective cannabinoid CB2 receptor activation, Nature Communications 14(1): 1447.
- Ortiz Zacarías N.V., Chahal K.K., Šimková T., Horst C. van der, Zheng Y., Inoue A., Theunissen E., Mallee L., Es D. van der, Louvel J., IJzerman A.P., Handel T.M., Kufareva I. & Heitman L.H. (2021), Design and characterization of an intracellular covalent ligand for CC chemokine receptor 2, Journal of Medicinal Chemistry 64(5): 2608-2621.
- Patberg M., Isaak A., Füsser F., Ortiz Zacarías N.V., Vinnenberg L., Schulte J., Michetti L., Grey L., Horst C. van der, Hundehege P., Koch O., Heitman L.H., Budde T. & Junker A. (2021), Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists, European Journal of Medicinal Chemistry 226: 113838.
- Ruano‑Ordás D., Burggraaff L., Liu R., Horst C. van der, Heitman L.H., Emmerich M.T.M., Mendez J.R., Yevseyeva I. & Westen G.J.P. van (2019), A multiple classifier system identifies novel cannabinoid CB2 receptor ligands, Journal of Cheminformatics 11: 66.