Berend Gagestein
Research staff member
- Name
- Dr. B. Gagestein
- Telephone
- +31 71 527 2727
- b.gagestein@lic.leidenuniv.nl
- ORCID iD
- 0000-0002-0993-6812
Research staff member
- Science
- Leiden Institute of Chemistry
- LIC/Chemical Biology
- LIC/CB/Molecular Physiology
- Bakker A.T., Kotsogianni I., Avalos Garcia M., Punt J.M., Liu B., Piermarini D., Gagestein B., Slingerland C.J., Zhang L., Willemse J.J., Ghimire L.B., Berg Richard J.H.B.N. van den, Janssen A.P.A., Ottenhoff T.H.M., Boeckel C.A.A. van, Wezel G.P. van, Ghilarov D., Martin N.I. & Stelt M. van der (2024), Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria, Nature Chemistry 16: 1462-1472.
- Mock E.D., Gagestein B. & Stelt M. van der (2023), Anandamide and other N-acylethanolamines: a class of signaling lipids with therapeutic opportunities, Progress in Lipid Research 89: 101194.
- Gagestein B., Stevens A.F., Fazio D., Florea B.I., Wel T. van der, Bakker A.T., Fezza F., Dulk J. den, Overkleeft H.S., Maccarrone M. & Stelt M. van der (2022), Chemical proteomics reveals off-targets of the anandamide reuptake inhibitor WOBE437, ACS Chemical Biology 17(5): 1174-1183.
- Bertheussen K., Plassche M.A.T. van de, Bakkum T., Gagestein B., Ttofi I., Sarris A.J.C., Overkleeft H.S., Stelt M. van der & Kasteren S.I. van (2022), Live-cell imaging of sterculic acid - a naturally occurring 1,2-cyclopropene fatty acid - by bioorthogonal reaction with turn-on tetrazine-fluorophore conjugates, Angewandte Chemie (International Edition) 61(38): e202207640.
- Gagestein B., von Hegedus J.H., Kwekkeboom J.C., Heijink M., Blomberg N., Wel T. van der, Florea B.I., Elst H. van der, Wals K., Overkleeft H.S., Giera M., Toes R.E.M., Ioan-Facsinay A. & Stelt M. van der (2022), Comparative photoaffinity profiling of omega-3 signaling lipid probes reveals prostaglandin reductase 1 as a metabolic hub in human macrophages, Journal of the American Chemical Society 144(41): 18938–18947.
- Voorneveld J., Florea B.I., Bakkum T., Mendowicz R.J., Veer M.S. van der, Gagestein B., Kasteren S.I. van, Stelt M. van der, Overkleeft H.S. & Filippov D.V. (2020), Olaparib-Based Photoaffinity Probes for PARP-1 Detection in Living Cells, ChemBioChem 21: 1-5.
- Gagestein B. (16 December 2020), Chemical tools to study lipid signaling (Dissertatie. Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University). Supervisor(s): Stelt M. van der & Overkleeft H.S.
- Koenders S.T.A., Gagestein B. & Stelt M. van der (2019), Opportunities for Lipid-Based Probes in the Field of Immunology. In: Cravatt B., Hsu K.L. & Weerapana E. (Eds.), Activity-Based Protein Profiling. Current Topics in Microbiology and Immunology no. 420. Berlin, Heidelberg: Springer,. 283-319.
- Grimm S.H., Gagestein B., Keijzer J.F., Liu N., Wijdeven R.H., Lenselink E.B., Tuin A.W., Nieuwendijk A.M.C.H. van den, Westen G.J.P. van, Boeckel C.A.A. van, Overkleeft H.S., Neefjes J. & Stelt M. van der (2019), Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors, Bioorganic & Medicinal Chemistry 27(5): 692-699.