Research project
Efficient and flexible platform to isolate and study bacteriophages
We aim to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples.
- Duration
- 2020 - 2021
- Contact
- Ariane Briegel
- Funding
- NWO Open Competition Domain Science - XS
Description
Viruses that only infect specific bacteria (bacteriophages) are promising agents to combat antibiotic-resistant bacterial infections. Bacteriophages have been utilized successfully to save lives in the past. However, the isolation, identification and characterization of suitable bacteriophages is a time-consuming process and requires up to several months to compile the appropriate bacteriophage mixtures. In the scope of this project, we propose to develop a microfluidic platform that can parallelize testing the performance and characteristics of pure, mixed and environmental bacteriophage samples. The platform will be cost-efficient, using a minimal amount of sample and equipment to be broadly accessible to many laboratories.