Universiteit Leiden

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Dissertation

Microvasculature in Microfluidics: matching complexity with compatibility

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug development, either due to a lack of efficacy or unforeseen off -target eff ects1-3.

Author
Duinen, V. van
Date
23 October 2019
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