PhD defence
Exploring liposome-targeted chemotherapy combined with immunotherapy in cancer
- Z. Gu
- Date
- Wednesday 4 December 2024
- Time
- Location
-
Academy Building
Rapenburg 73
2311 GJ Leiden
Supervisor(s)
- Prof.dr. P. ten Dijke
Summary
In current cancer therapy, nanomedicine especially liposomes, appears as an innovative strategy to improve therapeutical effects and overcome adverse effects. In this thesis, we aim at two aspects of leveraging liposomal formulations to enhance the efficacy of cancer chemotherapy and immunotherapy. Firstly, we employed liposomes to deliver multiple regiments simultaneously or subsequently to the target site, which successfully achieved a precise tumor control with a synergistic or addictive effects between chemotherapy and immunotherapy. Secondly, the liposomal formulation can reduce the severe side effects induced by either chemotherapy or/and immunotherapy while remaining pronounced immunomodulation on both the local and systemic immune system.
PhD dissertations
Approximately one week after the defence, PhD dissertations by Leiden PhD students are available digitally through the Leiden Repository, that offers free access to these PhD dissertations. Please note that in some cases a dissertation may be under embargo temporarily and access to its full-text version will only be granted later.
Press enquiries (journalists only)
General information
Beadle's Office
pedel@bb.leidenuniv.nl
+31 71 527 7211