Lecture
LED3 Lecture: Computational Drug Discovery
- Date
- Thursday 24 October 2024
- Time
- Location
-
Gorlaeus Building
Einsteinweg 55
2333 CC Leiden - Room
- CM1.26
We are very excited to welcome Andrew Leach from EMBL-EBI and the charity LifeArc for the next LED3 Lecture on October 24th at 4 p.m. in Gorlaeus room CM1.26. He will talk about “Democratizing Drug Discovery with Open Data”.
We hope to see many of you there. There will be a borrel after the lecture.
Abstract
Data is the lifeblood of drug discovery. It is generated in our experiments to be subsequently processed, analysed, visualized and integrated. It is the basis on which decisions are made. It underpins our intellectual property. It is at the heart of regulatory submissions. It helps us understand whether our medicines work and what side effects they may have. Increasingly, it enables us to develop and validate computational models. Much of the data generated within the drug discovery community is proprietary, yet for more than 50 years there have existed public data resources relevant to drug discovery, accessible to all. Many of these are developed and hosted by the European Bioinformatics Institute. In my talk I will focus on two of the EBI’s leading drug discovery data resources, ChEMBL and Open Targets, providing insights into their origins and how they are developed, resourced and funded today. I will also describe some applications of these and other data resources, to tackle a range of drug discovery research questions.