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Conference

LED3 PhD-Postdoc Symposium 2024

  • Laura Heitman, Nathaniel Martin, Marta Artola
Date
Thursday 20 June 2024
Time
Location
Gorlaeus Building
Einsteinweg 55
2333 CC Leiden
Room
CM.1.26

We are pleased to announce the first edition of the LED3 PhD/Postdoc symposium, a conference dedicated to diverse drug discovery research happening within the LED3 community with a strong focus on the work of PhDs and Postdocs.

Register now for this exciting event, where the latest insights & discoveries from early drug research will be shared & discussed.

We are proud to shine a spotlight on our PhDs and Postdocs, who will be presenting their research in both flash-talks (5 min) and longer talks (15 min). In addition, the symposium will feature keynote presentations from PIs within LED3. We are excited to announce plenary lectures from Prof. Nathaniel Martin (IBL), Prof. Laura Heitman (LACDR), and Dr. Marta Artola (LIC), who will showcase the work happening within their groups. 

 

Morning programme - CM.1.26

09:30 - 10:00 Walk-in and registration

10:00 - 10:10 Welcome by Bart de Smit, Vice-Dean of the Faculty of Science

10:10 - 10:40 Keynote Session 1 by Marta Artola (LIC)

10:40 - 11:40 Plenary Session 1 by LED3 PhDs & Postdocs

Jan Pascal Kahler (LACDR)
ReCHEMbinant protein engineering - synthetically enhanced protein therapeutics for Myc targeting

Daan van der Vliet (LIC)
Integrated molecular profiling of Multiple Sclerosis white matter lesions links inflammatory lipids to foamy microglia

Elma Mons (IBL)
Preclinical Evaluation of Guanidino Lipoglycopeptide Antibiotics with Best-in-Class Potential

11:40 - 12:00 From Lab to Start-up: Gijs Ruijgrok (LIC)
Unlocking the power of heparanase inhibition

Lunch programme - Atrium

12:30 - 13:00 Lunch

12:00 - 13:40 Poster session

Afternoon programme - CM.1.26

13:40 - 14:10 Keynote session 2 by Laura Heitman (LACDR)

14:10 - 15:10 Flash talks by LED3 PhDs & Postdocs

Julia Pols (LIC)
Target Identification of Covalent Inhibitors Binding to Cysteines in Pathogenic Bacteria

Sebastiaan Hamers (LUMC)
Selection and characterization of a peptide-based immune activator

Bert Beerkens (LACDR)
N-acyl-N-alkyl sulfonamide probes for the ligand-directed covalent labelling of GPCRs: the adenosine A2B receptor as a case study

Luis Rodrigo Becerra (IBL)
Evolutionary study of the ancient-like (βα)8-barrel PriA enzyme family in the biosynthesis of the nucleoside antibiotic Adechlorin

Merel Janssen (LIC)
Engineering Viscoelasticity in 3D Cell Culture Hydrogels through Dynamic Exchange

Halana Vlaming (LUMC)
Towards new antibiotics: targetingLegionella ADPribosyl transferases

David Meijer (IBL/WUR)
Advancing natural product engineering through machine-learning-powered biosynthetic gene cluster analysis

Eva George Matlalcuatzi (LIC)
Proteomic portrait on Staphylococcus aureus persisters using a bioorthogonal approach

15:10 - 15:30 Coffee break

15:30 - 16:30 Plenary session 2 by LED3 PhDs & Postdocs

Nataliia Machushynets (IBL)
Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity

Majlen Dilweg (LACDR)
Stereochemical optimization of N,2-substituted cycloalkylamines as norepinephrine reuptake inhibitors

Sophie Wintermans (LIC)
New high-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ1 riboswitch ligands

16:30 - 17:00 Keynote session 3 by Nathaniel Martin (IBL)

17:00 - 17:10 Closing remarks by Sebastian Pomplun (LACDR) and Stephan Hacker (LIC)

Evening programme - Atrium

17:10 - 20:00 Borrel and social event

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